Happening @ Michigan https://events.umich.edu/list/rss RSS Feed for Happening @ Michigan Events at the University of Michigan. PhD Defense: Josiah Simeth (August 5, 2020 2:00pm) https://events.umich.edu/event/75278 75278-19402991@events.umich.edu Event Begins: Wednesday, August 5, 2020 2:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Notice: This event will be held via BlueJeans. The link will be placed below.

BlueJeans: https://bluejeans.com/715371816

Measures of regional and global liver function are critical in guiding treatments for intrahepatic cancers, and liver function is a dominant factor in the survival of patients with hepatocellular carcinoma (HCC). Global and regional liver function assessments are important for defining the magnitude and spatial distribution of radiation dose to preserve functional liver parenchyma and reduce incidence of hepatotoxicity from radiation therapy (RT) for intrahepatic cancer treatment. This individualized liver function-guided RT strategy is critical for patients with heterogeneous and poor liver function, often observed in cirrhotic patients treated for HCC. Dynamic gadoxetic-acid enhanced (DGAE) magnetic resonance imaging (MRI) allows investigation of liver function through observation of the uptake of contrast agent into the hepatocytes.

This work seeks to determine if gadoxetic uptake rate can be used as a reliable measure of liver function, and to develop robust methods for uptake estimation with an interest in the therapeutic application of this knowledge in the case of intrahepatic cancers. Since voxel-by voxel fitting of the preexisting nonlinear dual-input two-compartment model is highly susceptible to over fitting, and highly dependent on data that is both temporally very well characterized and low in noise, this work proposes and validates a new model for quantifying the voxel-wise uptake rate of gadoxetic acid as a measure of regional liver function. This linearized single-input two-compartment (LSITC) model is a linearization of the pre-existing dual-input model but is designed to perform uptake quantification in a more robust, computationally simpler, and much faster manner. The method is validated against the preexisting dual-input model for both real and simulated data. Simulations are used to investigate the effects of noise as well as issues related to the sampling of the arterial peak in the characteristic input functions of DGAE MRI.

Further validation explores the relationship between gadoxetic acid uptake rate and two well established global measures of liver function, namely: Indocyanine Green retention (ICGR) and Albumin-Bilirubin (ALBI) score. This work also establishes the relationships between these scores and imaging derived measures of whole liver function using uptake rate. Additionally, the same comparisons are performed for portal venous perfusion, a pharmacokinetic parameter that has been observed to correlate with function, and has been used as a guide for individualized liver function-guided RT. For the patients assessed, gadoxetic acid uptake rate performs significantly better as a predictor of whole liver function than portal venous perfusion.
This work also investigates the possible gains that could be introduced through use of gadoxetic uptake rate maps in the creation of function-guided RT plans. To this end, plans were created using both perfusion and uptake, and both were compared to plans that did not use functional guidance. While the plans were generally broadly similar, significant differences were observed in patients with severely compromised uptake that did not correspond with compromised perfusion.

This dissertation also deals with the problem of quantifying uptake rate in suboptimal very temporally sparse or short DGAE MRI acquisitions. In addition to testing the limits of the LSITC model for these limited datasets (both realistic and extreme), a neural network-based approach to quantification of uptake rate is developed, allowing for increased robustness over current models.

Chair: Dr. Yue Cao

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Lecture / Discussion Thu, 23 Jul 2020 17:51:41 -0400 2020-08-05T14:00:00-04:00 2020-08-05T15:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
A Simulation Based Comparison of Point-of-Care Testing and Central Laboratory Testing (August 31, 2020 4:30pm) https://events.umich.edu/event/76322 76322-19687515@events.umich.edu Event Begins: Monday, August 31, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

In response to demand for fast and efficient clinical testing, the use of point-of-care testing (POCT) has become increasingly common in the United States. However, studies of POCT implementation have found that adopting POCT may not always be advantageous relative to centralized laboratory testing. We construct a simulation model of patient flow in an outpatient care setting to evaluate tradeoffs involved in POCT implementation across multiple dimensions, comparing measures of patient outcomes in varying clinical scenarios, testing regimes, and patient conditions. We find that POCT can significantly reduce clinical time for patients, as compared to traditional testing regimes, in settings where clinic and central testing areas are far apart. However, as distance from clinic to central testing area decreased, POCT advantage over central laboratory testing also decreased, in terms of time in the clinical system and estimated subsequent productivity loss. For example, testing for pneumonia resulted in an estimated average of 27.80 (central lab) versus 15.50 (POCT) total lost productive hours in a rural scenario, and an average of 14.92 (central lab) versus 15.50 (POCT) hours in a hospital-based scenario. Our results show that POCT can effectively reduce the average time a patient spends in the system for varying condition profiles and clinical scenarios. However, the number of total lost productive hours, a more holistic measure, is greatly affected by testing quality, where POCT often is at a disadvantage. Thus, it is important to consider factors such as clinical setting, target condition, testing costs, and test quality when selecting appropriate testing regime.

Vikrant Vaze is the Stata Family Career Development Associate Professor at Thayer School of Engineering at Dartmouth College. He is interested in developing optimization, game theory, and analytics approaches for improving large-scale complex systems, such as transportation and healthcare. In June 2020, Vikrant was selected as one of 85 engineers who will participate in the National Academy of Engineering’s 2020 US Frontiers of Engineering (NAE) Symposium. He holds two master’s degrees and a Ph.D. from the Massachusetts Institute of Technology in transportation and operations research, and a bachelor’s degree in civil engineering from the Indian Institute of Technology in Mumbai. Before joining academia, he worked as a Research Scientist in Philips Research and as an algorithmic trader on the Wall Street. Joint research work by Vikrant, his students and collaborators has been honored with best paper awards from AGIFORS in 2010, 2017, and 2019, from FAA/Eurocontrol in 2011 and 2017, and most recently with the INFORMS TSL Outstanding Paper Award in Air Transportation. He is the recipient of a number of academic and research honors including the Faculty Early Career Development Program (CAREER) Award from the U.S. National Science Foundation, as well as awards from the U.S. Department of Defense, Federal Aviation Administration, National Institutes of Health, World Wildlife Fund, and several other industry-sponsored awards.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Fri, 28 Aug 2020 14:21:43 -0400 2020-08-31T16:30:00-04:00 2020-08-31T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Vikrant Vaze, Ph.D.
DCMB / CCMB Weekly Seminar Series (September 9, 2020 4:00pm) https://events.umich.edu/event/76946 76946-19780535@events.umich.edu Event Begins: Wednesday, September 9, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Birth defects that interfere with craniofacial development can result in cognitive, neurosensory, and neuroendocrine defects that create life-long burdens for care. The forebrain, midbrain, hindbrain, five facial prominences, and pituitary gland develop between the first and second month of gestation in humans. Genetic defects that disrupt these processes cause a spectrum of disorders that range from holoprosencephaly (HPE) and septo-optic dysplasia (SOD) to pituitary hormone deficiencies. We screened a large cohort of Argentinean patients with congenital hypopituitarism and related disorders for mutations in known genes and identified novel pathogenic variants and examples of digenic disease. However, the majority of patients did not receive a molecular diagnosis, indicating the high degree of genetic complexity underlying these disorders and the need for additional gene discovery. The majority of known hypopituitarism genes were discovered through basic research in pituitary cell lines and mutant mice. To identify novel regulatory genes for pituitary organogenesis we analyzed differential binding of a key pituitary-specific transcription factor, POU1F1, in cell lines that represent pituitary progenitors and differentiated cells. We discovered that POU1F1 binding is associated with bZIP transcription factors in progenitors and with bHLH factors in differentiated cells. We also applied single cell RNA sequencing technology to analyze gene expression during pituitary organogenesis and discovered novel transcription factors that are candidates for driving cell specification as well as unique, rare cell types that are likely differentiation intermediates. Bioinformatic analyses have played key roles in advancing our knowledge of neuroendocrine birth defects and normal pituitary organogenesis.

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Lecture / Discussion Wed, 09 Sep 2020 08:26:42 -0400 2020-09-09T16:00:00-04:00 2020-09-09T17:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Sally Camper, Ph.D., Margery Shaw Distinguished University Professor of Human Genetics, Professor of Internal Medicine, University of Michigan
RNA Collaborative Seminar featuring: Sue Hammoud, Human Genetics & Justin Colacino, Environmental Health Sciences (September 9, 2020 4:00pm) https://events.umich.edu/event/75865 75865-19615931@events.umich.edu Event Begins: Wednesday, September 9, 2020 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

ZOOM REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_GjVNcoWtRG6OkzxSDmfb8A

"Same Same Different: Single cell RNAseq identifies conserved and divergent features of mammalian spermatogenesis"
Sue Hammoud, Ph.D.
Assistant Professor of Human Genetics
Website: https://hammoud.lab.medicine.umich.edu/

~and~

"Single cell transcriptomic profiling to understand breast stem cell heterogeneity in development and cancer disparities"
Justin Colacino. Ph.D.
Assistant Professor of Environmental Health Sciences
Website: https://www.colacinolab.com/

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Lecture / Discussion Wed, 26 Aug 2020 11:44:32 -0400 2020-09-09T16:00:00-04:00 2020-09-09T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion RNA Collaborative
Identifying Emergency Funds and How to Advocate for Making Room in Your Financial Aid Package (September 11, 2020 2:00pm) https://events.umich.edu/event/75507 75507-19513173@events.umich.edu Event Begins: Friday, September 11, 2020 2:00pm
Location: Off Campus Location
Organized By: CEW+

Advance registration is required; look for the Zoom link at the bottom of your confirmation email after registering.

This session will provide information about how you can seek emergency funds should you experience an emergency situation or one-time, unusual, unforeseen expense while in school. Information about the types of situations that qualify for emergency funds and where to seek funding will be covered during this presentation.

RSVP HERE: http://www.cew.umich.edu/events/identifying-emergency-funds-and-how-to-advocate-for-making-room-in-your-financial-aid-package

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Livestream / Virtual Tue, 18 Aug 2020 14:02:34 -0400 2020-09-11T14:00:00-04:00 2020-09-11T15:00:00-04:00 Off Campus Location CEW+ Livestream / Virtual A jar of spilled change
LHS Collaboratory Seminar Series Virtual Kick-Off: Academic Medical Centers as Learning Health Systems (September 17, 2020 9:00am) https://events.umich.edu/event/75856 75856-19615923@events.umich.edu Event Begins: Thursday, September 17, 2020 9:00am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Learning Health Systems (LHS) methods are now being implemented in interesting and varying ways by academic health centers and their clinical and translational science institutes across the country.
According to the Agency for Healthcare Research and Quality (AHRQ), the following are key attributes of Learning Health
Systems:

• Having leaders who are committed to a culture of continuous learning and improvement
• Systematically gathering and applying evidence in real-time to guide care
• Employing IT methods to share new evidence with clinicians to improve decision-making
• Promoting the inclusion of patients as vital members of the learning team
• Capturing and analyzing data and care experiences to improve care
• Continually assessing outcomes, refining processes and training to create a feedback cycle for learning and improvement

The LHS Collaboratory's fall seminar series virtual kick-off event will showcase the LHS experiences of three research-intensive academic centers that have been promoting LHS methods. We will be joined by distinguished senior colleagues from Duke,Vanderbilt, and Washington University, who will describe and discuss their institutions' work in this area. They will discuss strategies employed, investments made, challenges encountered, and successes achieved.

Panelists:
Kevin B. Johnson, MD, MS, FAAP, FACMI, Vanderbilt University
Christopher J. Lindsell, PhD, Vanderbilt University
Philip Payne, PhD, FACMI, Washington University
Michael Pencina, PhD, Duke University
Eric G. Poon, MD, MPH, Duke University

Discussant:
Carol R. Bradford, MD, MS, Executive Vice Dean for Academic Affairs, University of Michigan Medical School, Chief Academic Officer, Michigan Medicine, Professor of Otolaryngology-Head and Neck Surgery

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Lecture / Discussion Thu, 20 Aug 2020 09:45:31 -0400 2020-09-17T09:00:00-04:00 2020-09-17T11:00:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory Logo-blocks
DCMB / CCMB Weekly Virtual Seminar featuring Gioele La Manno, Ph.D. (EPFL Life Sciences Early Independent Research Scholar (ELISIR) (September 18, 2020 12:00pm) https://events.umich.edu/event/77057 77057-19836073@events.umich.edu Event Begins: Friday, September 18, 2020 12:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

I will present our comprehensive single-cell transcriptome atlas of mouse brain development spanning from gastrulation to birth. In this atlasing effort, we identified almost a thousand distinct cellular states, including the initial emergence of the neuroepithelium, different glioblasts, and a rich set of region-specific secondary organizers that we localize spatially. In this context, I will provide an example of how the spatially-resolved transcriptomic data can be particularly useful to interpret the complexity of such complex atlases.

Continuing in this direction, I will show the approach that we recently proposed as a general way to spatially resolve different types of next-generation sequencing data. We designed an imaging-free framework to localize high throughput readouts within a tissue by combining compressive sampling and image reconstruction. Our first implementation of this framework transformed a low-input RNA sequencing protocol into an imaging-free spatial transcriptomics technique (STRP-seq).

Finally, I will showcase the technique with the profiling of the brain of the Australian bearded dragon Pogona vitticeps. With this analysis, we revealed the molecular anatomy of the telencephalon of this lizard and provided evidence for a marked regionalization of the reptilian pallium and subpallium.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Wed, 16 Sep 2020 11:27:53 -0400 2020-09-18T12:00:00-04:00 2020-09-18T13:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Gioele La Manno, Ph.D. (EPFL Life Sciences Early Independent Research Scholar (ELISIR) École polytechnique fédérale de Lausanne ‐ EPFL Swiss Federal Institute of Technology Lausanne)
CHEPS Alums and their Experience Fighting COVID-19 (September 21, 2020 4:30pm) https://events.umich.edu/event/77491 77491-19875789@events.umich.edu Event Begins: Monday, September 21, 2020 4:30pm
Location:
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

As the COVID-19 pandemic became widespread, health systems had to adjust and problem-solve rapidly. On this panel, alumni of the Center for Healthcare Engineering and Patient Safety will discuss how they and their institutions responded to COVID-19 and worked to address new operational challenges while keeping patients and healthcare workers safe.

Joe East is Director of Patient Flow at Maine Medical Center where he is using systems engineering to improve patient care. He holds an MHSA in Health Care Administration/Management and an MSE in Industrial and Operations Engineering with a concentration in Healthcare Engineering and Patient Safety from the University of Michigan. In his time at Maine Medical he has improved discharge and patient placement processes, worked on nurse staffing models, and created actionable dashboards and reports.

Pamela Martinez is a Process Engineer and Project Manager for the UCHealth CARE Innovation Center. She holds an MSE in Industrial and Operations Engineering from the University of Michigan with a concentration in Healthcare Engineering and Patient Safety. Pam’s focus is to improve the efficiency, safety, and quality of healthcare delivery through Industrial and Systems Engineering principles.

Bill Zhang is Director of Hospital and Procedural Services at Kaiser Permanente. He holds an MPH in Health Care Administration/Management and an MSE in Industrial and Operations Engineering with a concentration in Healthcare Engineering and Patient Safety from the University of Michigan. He works to utilize technology & engineering tools to transform healthcare and make positive impact on people’s lives by developing outcome-oriented, cost-effective and efficient healthcare solutions.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Workshop / Seminar Mon, 21 Sep 2020 11:37:18 -0400 2020-09-21T16:30:00-04:00 2020-09-21T17:30:00-04:00 Center for Healthcare Engineering & Patient Safety (CHEPS) Workshop / Seminar photos of speakers & seminar information
Older Adults, Tech Use, and Social Well-Being during COVID-19 and Beyond (September 21, 2020 4:30pm) https://events.umich.edu/event/77493 77493-19875791@events.umich.edu Event Begins: Monday, September 21, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Nearly one in three older adults in the U.S. experienced some form of loneliness in 2019. The COVID-19 pandemic significantly restricted older adults’ (ages 65+) in-person social interactions, likely increasing loneliness among this demographic. Due to these restrictions, older adults have started to change their relationships with technology to communicate with family and friends at a distance using smartphones and computers. However, these technologies may not be accessible for all older adults. Voice-based technologies such as Amazon Alexa and Google Assistant can be more accessible to those with motor challenges or vision loss/blindness, yet have not been studied in-depth for how they can support older adult’s well-being. In this talk, I will discuss (1) a recent interview study with older adults COVID-19 technology use and (2) a recent analysis of more than 50,000 queries older adults made to the Amazon Alexa for social well-being. Early findings point to positive and negative aspects of using technology for well-being and aging.

Robin Brewer is an Assistant Professor in the School of Information at the University of Michigan. She also holds a courtesy appointment in Computer Science and Engineering. Dr. Brewer’s research in Human-Computer Interaction (HCI) asks (1) how experiences with technology can be more accessible to digitally constrained communities and (2) how these communities use technology for social well-being. Much of her work focuses on older adults and people with vision impairments. Dr. Brewer holds a Ph.D. in Technology and Social Behavior from Northwestern University, M.S. in Human-Centered Computing from University of Maryland - Baltimore County, and B.S. in Computer Science from the University of Maryland - College Park.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Mon, 21 Sep 2020 11:54:41 -0400 2020-09-21T16:30:00-04:00 2020-09-21T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion photo of speaker with event information
2020 Precision Health Virtual Symposium (September 23, 2020 8:45am) https://events.umich.edu/event/75090 75090-19216540@events.umich.edu Event Begins: Wednesday, September 23, 2020 8:45am
Location: Off Campus Location
Organized By: Precision Health

Join us for a full-day virtual event celebrating and exploring the latest research in the fast-moving, multidisciplinary field of precision health.

This year's event focuses on the engagement of community participants to do research and the positive impact research can have on communities. Featuring national and local experts from engineering, medicine, nursing, pharmacy, public health, and many other areas, this event will provide thought-provoking sessions from multiple perspectives.

The morning session is geared toward researchers, with speakers sharing best practices and the importance of engaging a community. The afternoon session will be appropriate for both research participants and researchers, as we focus on the impact of research on community. You may attend either or both sessions. All are welcome.

A virtual poster session will feature work by funded Precision Health Investigators and other invited research groups.

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Livestream / Virtual Mon, 24 Aug 2020 14:37:59 -0400 2020-09-23T08:45:00-04:00 2020-09-23T15:15:00-04:00 Off Campus Location Precision Health Livestream / Virtual 2020 Precision Health Virtual Symposium
DCMB / CCMB Weekly Virtual Seminar (September 23, 2020 4:00pm) https://events.umich.edu/event/77143 77143-19798542@events.umich.edu Event Begins: Wednesday, September 23, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Talk title: Decision Support System Applications in Dentistry

Dr. Lucia Cevidanes is the Thomas and Doris Graber Professor of Dentistry and Associate Professor at the Department of Orthodontics at the University of Michigan, and a Diplomate of the American Board of Orthodontics. She is a practicing clinician who has published over 150 manuscripts on 3D imaging for which she has received research grants from the American Association of Orthodontics Foundation and the National Institute of Dental and Craniofacial Research. Her work has been recognized by the American Association of Orthodontists Thomas M. Graber Award, the B F Dewel Award, Milo Hellman Award, and the Wuehrmann award from the American Academy of Oral and Maxillofacial Radiology. Her interests include Artificial Intelligence and 3D Imaging to solve difficult clinical problems in dentistry, studying current and new treatment approaches and technical procedures, and understanding treatment outcomes for craniofacial anomalies and dentofacial deformities.

Zoom Link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Fri, 11 Sep 2020 15:27:53 -0400 2020-09-23T16:00:00-04:00 2020-09-23T17:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Dr. Lucia Cevidanes is the Thomas and Doris Graber Professor of Dentistry and Associate Professor at the Department of Orthodontics at the University of Michigan
Joint Institute 10-year Celebration (September 24, 2020 7:00am) https://events.umich.edu/event/77360 77360-19844062@events.umich.edu Event Begins: Thursday, September 24, 2020 7:00am
Location: Off Campus Location
Organized By: UMMS Global REACH

Join representatives from Michigan Medicine and Peking University Health Science Center, along with renowned leaders in national and international academic medicine, for a virtual celebration of the Joint Institute.

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Livestream / Virtual Thu, 17 Sep 2020 10:31:16 -0400 2020-09-24T07:00:00-04:00 2020-09-24T09:00:00-04:00 Off Campus Location UMMS Global REACH Livestream / Virtual Joint Institute 10-year Celebration
CLINICAL SIMULATION CENTER BROWN BAG SERIES (September 29, 2020 12:00pm) https://events.umich.edu/event/77752 77752-19909894@events.umich.edu Event Begins: Tuesday, September 29, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

All Michigan Medicine faculty and staff are invited to attend the next installment of the Clinical Simulation Center Brown Bag series.

The series is designed to promote collaboration and best practices in simulation-based education and research and will allow faculty, staff and learners the opportunity to learn and share best practices in simulation-based education and assessment.

The next event, which will be held at noon on Tuesday, September 29th. James Cooke, MD, will discuss "Overarching Themes from ACS-AEI Accreditation Survey Best Practices 2011-2019.”

Click here for more information: https://medicine.umich.edu/dept/clinical-simulation-center/events/202009/csc-brown-bag-series-september-2020-part-ii

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Lecture / Discussion Fri, 25 Sep 2020 16:43:35 -0400 2020-09-29T12:00:00-04:00 2020-09-29T13:00:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Adult resuscitation training at CSC
CSC Brown Bag Seminar (September 29, 2020 12:00pm) https://events.umich.edu/event/77778 77778-19923732@events.umich.edu Event Begins: Tuesday, September 29, 2020 12:00pm
Location: Off Campus Location
Organized By: Clinical Simulation Center

Dr. James Cooke, Associate Professor Departments of Family Medicine & Learning Health Sciences and Executive Director of the Michigan Medicine Clinical Simulation Center will present compiled themes from 9 years of simulation center accreditation data which distills best practices from 247 accreditation reviews into eight overarching themes on everything from curriculum development to governance. Findings were also electronically published in ahead of print and available at https://www.sciencedirect.com/science/article/pii/S0039606020303858

Please share this with any simulation colleagues or health system/medical school administrators who might be interested.

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Workshop / Seminar Sun, 27 Sep 2020 11:22:20 -0400 2020-09-29T12:00:00-04:00 2020-09-29T13:00:00-04:00 Off Campus Location Clinical Simulation Center Workshop / Seminar CSC-Med Sci 2 PICU
Center for Global Health Equity Introductory Seminar (September 29, 2020 5:00pm) https://events.umich.edu/event/77700 77700-19901736@events.umich.edu Event Begins: Tuesday, September 29, 2020 5:00pm
Location: Off Campus Location
Organized By: Center for Global Health Equity

Please join us for the Introductory Seminar for the Center for Global Health Equity, where we will discuss:
What is the purpose of the Center?
What has been our journey to date?
Where are we going?

Speakers Include:
Bhramar Mukherjee, PhD
Nancy Love, PhD
Joseph Kolars, MD
John Ayanian, MD, MPP
Laura Rozek, PhD
Andries Coetzee, PhD

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Workshop / Seminar Thu, 24 Sep 2020 16:32:00 -0400 2020-09-29T17:00:00-04:00 2020-09-29T18:30:00-04:00 Off Campus Location Center for Global Health Equity Workshop / Seminar Event Speakers
DCMB / CCMB Weekly Virtual Seminar - Xiaotian Zhang, Ph.D. (September 30, 2020 4:00pm) https://events.umich.edu/event/77549 77549-19883820@events.umich.edu Event Begins: Wednesday, September 30, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The human genome is organized into small compartments to allow for the proper gene expression regulation in the physiological process. With the advance of next-generation sequencing and imaging technologies, we can now investigate how the genome is folded into 3D space and how the 3D genomic organization regulates gene expression in development and disease. Currently, most of the studies are focusing on CTCF and cohesion complex which partner together to facilitate the formation of topological associated domains (TAD). The presenter will mainly discuss his recently published work on the DNA methylation -3D genomics cross-talk. Unpublished work on the 3D genomics in AML will be discussed as well.

Short bio: Xiaotian Zhang obtained his Ph.D. at Baylor College of Medicine with Dr. Margaret Goodell on the role of DNA methylation synergy in leukemia development. He was previously the Van Andel special postdoc fellow in Gerd Pfeifer lab working on the 3D genomics in normal hematopoietic stem cell and leukemia. He is now a Research track faculty (Research Investigator) in Pathology Department under Tomek Cierpicki working on the HOXA regulation in leukemia development. Xiaotian's research focuses on the epigenetic regulation of key pathogenic genes in leukemia, particularly on high order chromatin structure in disease. He published on Nature Genetics, Molecular Cell and Blood as the first author and corresponding authors.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Tue, 22 Sep 2020 09:31:31 -0400 2020-09-30T16:00:00-04:00 2020-09-30T17:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Xiaotian Zhang, Ph.D., Research Investigator in the Department of Pathology at the University of Michigan
RNA Seminar featuring: Chase Weidmann, Washington University School of Medicine in St. Louis (October 5, 2020 4:00pm) https://events.umich.edu/event/76147 76147-19665691@events.umich.edu Event Begins: Monday, October 5, 2020 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

ZOOM REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_y9HTFl5RSOSJTJ5qtlhVcw

Keywords: mRNA regulation, noncoding RNA, RNA Structure, RNP granules

Abstract:
Chase Weidmann, Ph.D. has contributed broadly to the field of RNA Biology during his career, studying mechanisms of codon bias during translation, post-transcriptional regulation of mRNAs by RNA-binding proteins, the folding of long non-coding RNAs, and how RNA-protein interaction networks contribute to the function and assembly of functional RNP particles. Chase developed a chemical probing strategy and next-gen sequencing technology, called RNP-MaP, that maps the location of and cooperation between multi-protein networks on RNAs in live cells. Going forward, Chase is interested in understanding how alterations in RNA-binding protein profiles, a cell’s “RBPome”, confer deleterious activities onto noncoding RNAs in human disease, especially in cancer. To further empower this work and his future research program, Chase is now generating and integrating protein mass spectrometry data into his RBPome projects.

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Lecture / Discussion Wed, 16 Sep 2020 09:01:52 -0400 2020-10-05T16:00:00-04:00 2020-10-05T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion photo
A Virtual Event: Per- and polyfluoroalkyl substances (PFAS): Exposure, Toxicity, and Policy (October 7, 2020 1:00pm) https://events.umich.edu/event/77430 77430-19854020@events.umich.edu Event Begins: Wednesday, October 7, 2020 1:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

This M-LEEaD Virtual Symposium will focus on issues related to exposure, toxicity, and policy in the unfolding PFAS contamination across Michigan and globally. Speakers will each focus on one of these topics related to their expertise.

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Livestream / Virtual Fri, 18 Sep 2020 12:36:19 -0400 2020-10-07T13:00:00-04:00 2020-10-07T15:00:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Livestream / Virtual 10.7.20 Poster
DCMB / CCMB Weekly Seminar (October 7, 2020 4:00pm) https://events.umich.edu/event/78232 78232-19996937@events.umich.edu Event Begins: Wednesday, October 7, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The chromosomes of the human genome are organized in three-dimensions by compartmentalizing the cell nucleus and different genomic loci also interact with each other. However, the principles underlying such nuclear genome organization and its functional impact remain poorly understood. In this talk, I will introduce some of our recent work in developing machine learning methods by utilizing whole-genome mapping data to study the higher-order genome organization. Our methods reveal the spatial localization of chromosome regions and exploit chromatin interactome patterns within the cell nucleus in different cellular conditions, across mammalian species, and also in single-cell resolution. We hope that these algorithms will provide new insights into the principles of nuclear spatial organization.

Bio: Jian Ma is an Associate Professor in the Computational Biology Department within the School of Computer Science at Carnegie Mellon University. He was previously on the faculty of the University of Illinois at Urbana-Champaign. His lab develops algorithms to study the structure and function of the human genome with a focus on nuclear organization, gene regulation, comparative genomics, and single cell biology. He received several awards, including an NSF CAREER award and a Guggenheim Fellowship. He is the Contact PI of a UM1 Center project in the NIH 4D Nucleome Program (Phase 2; 2020-2025). https://www.cs.cmu.edu/~jianma/

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 06 Oct 2020 12:47:39 -0400 2020-10-07T16:00:00-04:00 2020-10-07T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Virtual Physician Job Shadow: Watch Live Shoulder Surgery (October 8, 2020 8:45am) https://events.umich.edu/event/77717 77717-19907692@events.umich.edu Event Begins: Thursday, October 8, 2020 8:45am
Location: Off Campus Location
Organized By: LSA Opportunity Hub

Elective surgeries are a cornerstone of our healthcare system that’s focused on increasing a patient’s well-being and quality of life. At a time when elective surgeries have been impacted significantly by the pandemic with longer waiting periods, reschedules, or even cancellations, the ability to schedule those potentially life-changing operations in advance has been compromised. Join us for a live look into an arthroscopic rotator cuff surgery as Dr. Nikhil Verma uses advanced surgical techniques to fix a tear in a torn rotator cuff.


About Dr. Verma:

Dr. Verma is a Sports Medicine and Shoulder physician who performs over 500 procedures per year. He specializes in the treatment of the shoulder, elbow, and knee with an emphasis on advanced arthroscopic reconstructive techniques. He is the Director of the Division of Sports Medicine and Director of the Sports Medicine Fellowship Program at Rush University Medical Center. In addition, Dr. Verma serves as a team physician for the Chicago White Sox and Chicago Bulls.


You should attend this session if you are:

- A liberal arts and/or science undergraduate student
- Searching for opportunities to shadow a physician at their clinical practice
- Exploring careers and specialities in medicine and healthcare
- Looking to explore different medical fields from the perspective of a physician

What you’ll gain from attending:

- The opportunity to watch a live surgery performed by a physician and his team using leading technology in the field
- The chance to ask the physician questions about the surgery and his work more broadly
- Gain insight into how the physicians are handling elective surgeries during COVID-19

RSVP today to reserve your spot to view this live surgery. Seats will be capped at 95. Once your RSVP is complete, you will receive a confirmation email with the event details and a link to access the live viewing before the event takes place.

Elective surgeries are a cornerstone of our healthcare system that’s focused on increasing a patient’s well-being and quality of life. At a time when elective surgeries have been impacted significantly by the pandemic with longer waiting periods, reschedules, or even cancellations, the ability to schedule those potentially life-changing operations in advance has been compromised. Join us for a live look into an arthroscopic rotator cuff surgery as Dr. Nikhil Verma uses advanced surgical techniques to fix a tear in a torn rotator cuff.


About Dr. Verma:


Dr. Verma is a Sports Medicine and Shoulder physician who performs over 500 procedures per year. He specializes in the treatment of the shoulder, elbow, and knee with an emphasis on advanced arthroscopic reconstructive techniques. He is the Director of the Division of Sports Medicine and Director of the Sports Medicine Fellowship Program at Rush University Medical Center. In addition, Dr. Verma serves as a team physician for the Chicago White Sox and Chicago Bulls.


You should attend this session if you are:

A liberal arts and/or science undergraduate student
Searching for opportunities to shadow a physician at their clinical practice
Exploring careers and specialities in medicine and healthcare
Looking to explore different medical fields from the perspective of a physician
What you’ll gain from attending:

The opportunity to watch a live surgery performed by a physician and his team using leading technology in the field
The chance to ask the physician questions about the surgery and his work more broadly
Gain insight into how the physicians are handling elective surgeries during COVID-19
RSVP today to reserve your spot to view this live surgery. Seats will be capped at 75. Once your RSVP is complete, you will receive a confirmation email with the event details and a link to access the live viewing before the event takes place.

The LSA Opportunity Hub aims to deliver inclusive and accessible experiences and welcomes all LSA students to participate. This event will be hosted on Zoom (learn more about Zoom accessibility) and can be accessed by phone or computer. Presentation materials will be shared in advance and live captioning will be provided. To request other accommodations please contact Paige Baker at paigebak@umich.edu or 734.763.4674. so we can make arrangements.

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Livestream / Virtual Tue, 06 Oct 2020 09:31:37 -0400 2020-10-08T08:45:00-04:00 2020-10-08T09:45:00-04:00 Off Campus Location LSA Opportunity Hub Livestream / Virtual two surgeons in operating room
Engineering an immunological niche for early detection of immune dysfunction (October 8, 2020 12:00pm) https://events.umich.edu/event/77515 77515-19877791@events.umich.edu Event Begins: Thursday, October 8, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Lonnie Shea, PhD
William and Valerie Hall Chair
Steven A. Goldstein Collegiate Professor
Biomedical Engineering
University of Michigan

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Presentation Mon, 21 Sep 2020 13:40:07 -0400 2020-10-08T12:00:00-04:00 2020-10-08T13:00:00-04:00 Off Campus Location Office of Research School of Dentistry Presentation flyer
How Lean Culture is Fighting Against the Coronavirus (October 12, 2020 4:30pm) https://events.umich.edu/event/78063 78063-19957560@events.umich.edu Event Begins: Monday, October 12, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

We’ve all been impacted by the COVID-19 pandemic in different ways. For me, one of the ways was receiving a call to “deploy” to our ventilator manufacturing facility to help make an unprecedented volume of ventilators as fast as possible. The world needed ventilators to fight COVID-19 and we needed to ramp production using our best manufacturing methodologies.Using Lean techniques was once described by one of its founding leaders, Taiichi Ohno, as “looking at the timeline, from the moment the customer gives us an order to the point when we collect the cash. And we are reducing the timeline by reducing the non-value adding wastes.” GE Healthcare has incorporated Lean into its operational fabric just as described in the quote to delivery reliable daily output as well as to take on new manufacturing challenges. In this presentation, I will describe the challenge that COVID-19 presented to our company, to the production process & to the cross-functional group of people involved in supporting production. To tell this story, I will be sharing some basics about Lean Methodologies and how it influenced our approach, communications & the execution of an unprecedented ventilator output. Finally, I will discuss how these same methodologies and approach can be used to positively impact your business, career, or challenge you’re facing.

Passion: My passion is serving the Healthcare community by educating eager learners, utilizing Lean-6 Sigma methodologies & incorporating Advanced Technologies to challenge the status quo & bring about meaningful improvement.

Experience: I’ve been with GE Healthcare for 15 years in a variety of roles from a manufacturing engineer, to a site & national Lean Leader to a multi-state field service director. These roles have including manufacturing, service & commercial elements to them and always included a primary focus on healthcare. Additionally, I have worked within the aviation, energy & financial industries through cross-business projects. With my experience, I was recently called on by GE to help during the COVID-19 response to drive increased output, improved quality & to build a supportive culture in our ventilator manufacturing business. Additionally, I have used this knowledge to start an education & consulting group focused on Lean methodologies called ripple Solutions LLC. My small business has allowed me to expand outside of healthcare & connect with the printing, distribution, university & non-healthcare manufacturing industries.

Education: I have a degree in Industrial Engineering with additional courses in Medical Sciences from University of Michigan, class of 2007. I am a GE Healthcare Operations Management Leadership Program graduate, I’m a certified Black Belt in DMAIC Lean Six Sigma and I’m Green Belt certified in DFSS Six Sigma. I have also received extensive GE Healthcare & Shingijtsu Lean training.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 01 Oct 2020 14:52:38 -0400 2020-10-12T16:30:00-04:00 2020-10-12T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion photo of speaker with event information
DCMB / CCMB Weekly Seminar (October 14, 2020 4:00pm) https://events.umich.edu/event/78234 78234-19996940@events.umich.edu Event Begins: Wednesday, October 14, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Gaussian processes provide flexible non-parametric models of data and we are using them to model temporal and spatial patterns in gene expression. Single-cell omics measurements are destructive and one cannot follow the high-dimensional dynamics of genes across time in one cell. Similarly, the spatial context of cells is often lost or only known with reduced resolution. Computational methods are widely used to infer pseudo-temporal orderings of cells or to infer spatial locations. We show how Gaussian processes (GPs) can be used to model temporal and spatial relationships between genes and cells in these datasets. As examples I will show how we use Bayesian GPLVMs with informative priors to infer pseudo-temporal orderings for single-cell time course data [1] and branching GPs to identify gene-specific bifurcation points across pseudotime [2]. Gene expression data are often summarized as counts and there may be many zero values in the data due to limited sequencing depth. We therefore recently extended these methods to use negative binomial or zero-inflated negative binomial likelihoods and we show that this can lead to much improved performance over standard Gaussian noise models when identifying spatially varying genes from spatial transcriptomics data [3].

[1] Ahmed, S., Rattray, M., & Boukouvalas, A. (2019). GrandPrix: scaling up the Bayesian GPLVM for single-cell data. Bioinformatics, 35(1), 47-54.

[2] Boukouvalas, A., Hensman, J., & Rattray, M. (2018). BGP: identifying gene-specific branching dynamics from single-cell data with a branching Gaussian process. Genome biology, 19(1), 65.

[3] BinTayyash, N., Georgaka, S., John, S. T., Ahmed, S., Boukouvalas, A., Hensman, J., & Rattray, M. (2020). Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments. Bioarxiv https://doi.org/10.1101/2020.07.29.227207

Short bio: Magnus Rattray is Professor of Computational and Systems Biology at the University of Manchester and Director of the Institute for Data Science & AI. He works on the development of methods for machine learning and Bayesian inference with applications to large-scale biological and medical datasets. He has a long-standing interest in longitudinal data analysis and a more recent interest in modelling single-cell, spatial omics and live cell imaging microscopy data. He is a Fellow of the ELLIS Health Programme and the Alan Turing Institute and his research is funded by a Wellcome Trust Investigator Award.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 06 Oct 2020 13:35:21 -0400 2020-10-14T16:00:00-04:00 2020-10-14T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Magnus Rattray, PhD (Professor of Computational and Systems Biology, University of Manchester)
Honors Grand Rounds with Mohammed Moursi, MD (October 14, 2020 7:00pm) https://events.umich.edu/event/76326 76326-19687519@events.umich.edu Event Begins: Wednesday, October 14, 2020 7:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

Join Stephanie Chervin, Honors premed advisor, for a virtual live discussion with Honors alum Mohammed Moursi, MD; Chief of Vascular Surgery University of Arkansas. This program is for current LSA Honors Program students only. A link to the virtual event will be sent to all registrants before the event.

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Presentation Fri, 28 Aug 2020 15:29:24 -0400 2020-10-14T19:00:00-04:00 2020-10-14T20:00:00-04:00 Off Campus Location LSA Honors Program Presentation Dr. Moursi
3D organization of human genome in development and disease – A perspective from 3D genome engineering (October 15, 2020 12:00pm) https://events.umich.edu/event/78431 78431-20044394@events.umich.edu Event Begins: Thursday, October 15, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Xiaotian Zhang, PhD
Research Investigator
Department of Pathology
Tomasz Cierpicki/Jolanta Grembecka lab
University of Michigan

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Lecture / Discussion Mon, 12 Oct 2020 12:04:51 -0400 2020-10-15T12:00:00-04:00 2020-10-15T13:00:00-04:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Zhang
The Massey Family Foundation Virtual TBI Conference (October 15, 2020 1:00pm) https://events.umich.edu/event/77046 77046-19790555@events.umich.edu Event Begins: Thursday, October 15, 2020 1:00pm
Location: Off Campus Location
Organized By: Michigan Center for Integrative Research in Critical Care (MCIRCC)

The Michigan Center for Integrative Research in Critical Care (MCIRCC) invites you to the 2020 Massey Family Foundation Virtual TBI Conference.

Supported by the Joyce & Don Massey Family Foundation, the conference aims to improve the outcomes of those who suffer severe traumatic brain injuries by sharing the latest insights and innovations in the field, and by supporting technology development and translational and clinical research that impacts the “golden hours” of care.

The 2020 conference will kick off with a presentation by keynote speaker Daniel Spaite, MD, FACEP, Virginia Piper Distinguished Chair of Emergency Medicine and Director of the EMS Research Collaboration at the University of Arizona College of Medicine. The afternoon’s events will also include a roundtable discussion and live Q&A with a panel of field and industry leaders.

For more information and to register: https://mcircc.umich.edu/tbi2020

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Conference / Symposium Thu, 10 Sep 2020 13:19:23 -0400 2020-10-15T13:00:00-04:00 2020-10-15T15:30:00-04:00 Off Campus Location Michigan Center for Integrative Research in Critical Care (MCIRCC) Conference / Symposium Massey Family Foundation Virtual TBI Conference
The Psychology of Pathogen Avoidance: How Does It Work and How Relevant Is It for Understanding Pandemic Behavior? (October 15, 2020 5:00pm) https://events.umich.edu/event/78467 78467-20050321@events.umich.edu Event Begins: Thursday, October 15, 2020 5:00pm
Location: Off Campus Location
Organized By: Weinberg Institute for Cognitive Science

Infectious diseases have been some of humanity's biggest killers. Fortunately, we possess an evolved psychology of pathogen avoidance - a system of mental mechanisms that help us identify, track, and respond to such dangers, thereby reducing risks of infection. Unfortunately, this system is imperfect - we mistake which information is diagnostic, leading to faulty assumptions, pernicious attitudes, and bad decisions. I will review recent work in our lab focusing on how we conceptualize pathogen threats and consequences of this process. Additionally, I will discuss when our understanding of pathogen avoidance psychology can inform explanations of pandemic behavior, and more importantly, why it might not.

Zoom link: https://umich.zoom.us/j/96257205534
Meeting ID: 962 5720 5534
Password: cogsci

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Lecture / Discussion Tue, 13 Oct 2020 09:22:13 -0400 2020-10-15T17:00:00-04:00 2020-10-15T18:00:00-04:00 Off Campus Location Weinberg Institute for Cognitive Science Lecture / Discussion csc logo
Tracking A Pandemic: An Analytical View of the COVID-19 Progression and Implications for Business Plans to Re-Engage in the Economy (October 19, 2020 4:30pm) https://events.umich.edu/event/78333 78333-20010773@events.umich.edu Event Begins: Monday, October 19, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

The SARS-CoV-2 virus caused widespread disruption across the globe, affecting literally every aspect of human life. The business environment was not spared in this disruption, as customers, the workforce, workplace environments and supply chains were each turned upside-down, almost overnight. Operating practices needed to be challenged, re-engineered and re-adopted – at the speed of business. That is akin to replacing the aircraft engine while the plane is mid-flight.

The challenge faced by business leaders from the outset of the pandemic, and remains true today, is that objective, analytical information on the state of the virus was and remains woefully inadequate. Further, every organization operating in multiple geographical and political jurisdictions has to navigate different and every-changing rules governing the ability to conduct operations.

In mid-March, I launched an effort to build a repository of critical virus-related information (tests, positives, infections, recoveries, fatalities) at various levels of granularity – world, country, state or province, and metropolitan area. From this, I established a daily reporting mechanism and underlying analyses, designed to equip business leaders, economic and investment advisors and clinicians with insight about the state of the virus spread and underlying trends. My intent was to inform these leaders with actionable intelligence, free of both the fearmongering and denial perspectives that were dominating the general and social media.

These efforts have resulted in my direct engagement with four organizations’ operational planning efforts around the pandemic: two for-profit organizations involved in the manufacture and distribution of critical medical/life sciences products to consumers around the globe, a not-for-profit agency supporting families of critically-ill children and a governmental agency charged with administering a state-wide pandemic response effort. Additionally, I provide daily reports on the state of the virus to an estimated 2,000 clinicians, health organization managers, economists and investment managers.

These lessons provide strong insight for the analytical practitioner. Through this effort, I have discovered the challenges of making actionable sense of data from a novel virus . . . in real-time. Data sources and definitions are in constant flux, external reporting lacks analytical rigor, and, new knowledge frequently trumps previously held scientific beliefs. More profoundly, models reported on and used extensively by government officials are often accepted as dogma but, may be nothing more than assumptions built upon several more layers of assumptions.

Mark currently serves as the Board Chair of Crown Healthcare Laundry Inc., a Quilvest Private Equity-portfolio company and as Strategic Advisor to Terso Solutions Inc., a subsidiary of Promega that provides Real Time Location Services (RTLS) for field-based inventory of leading medical implant and biotech companies.

He previously served as chief strategist and business intelligence officer for Owens & Minor, Inc.; as a Partner in the healthcare consulting practice at Ernst & Young, where he launched the firm’s health care supply chain practice; and as a Management Engineer at the Detroit Medical Center.

Mark also serves on the National Advisory Board of the Congenital Heart Center at C.S. Mott Children’s Hospital at the University of Michigan, and on the Advisory Board of the Medical Device Supply Chain Council. He recently completed two terms on the Board of the Bellwether League Inc.

In the midst of the COVID-19 situation, Mark is producing an objective and analytical daily report on the virus progression in the US and worldwide. This report has become a go-to source for nearly 2,000 physicians, scientists, health system and supplier executives, economists, investment bankers and, one former head of the Centers for Medicare and Medicaid Services.

Mark holds an MBA from the Ross School of Business at the University of Michigan and a Bachelor of Science in Industrial & Operations Engineering, also from the University of Michigan.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 08 Oct 2020 11:38:55 -0400 2020-10-19T16:30:00-04:00 2020-10-19T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion photo of speaker with event information
CSCS/MIDAS/MICDE Seminar | Predicting the second wave of COVID-19 in Washtenaw County, MI (October 20, 2020 11:30am) https://events.umich.edu/event/76629 76629-19733025@events.umich.edu Event Begins: Tuesday, October 20, 2020 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

This seminar is co-sponsored by the Michigan Institute for Computational Discovery & Engineering (MICDE) and the Michigan Institute for Data Science (MIDAS)

VIRTUAL SEMINAR LINK: myumi.ch/v2ZYv

In this work, we study and predict the spread of COVID-19 in Washtenaw County, MI through applying a discrete and stochastic network-based modeling framework. In this framework, we construct contact networks based on synthetic population datasets specific for Washtenaw County that are derived from US Census datasets. We assign individuals to households, workplaces, schools, and group quarters (such as prisons or long term care facilities). In addition, we assign casual contacts to each individual at random. Using this framework, we explicitly simulate Michigan-specific government-mandated workplace and school closures as well as social distancing measures. We perform sensitivity analyses to identify key model parameters and mechanisms contributing to the observed disease burden in the three months following the first observed cases of COVID-19 in Michigan. We then consider several scenarios for relaxing restrictions and reopening workplaces to predict what actions would be most prudent. In particular, we consider the effects of 1) different timings for reopening, and 2) different levels of workplace vs. casual contact re-engagement. Through simulations and sensitivity analyses, we explore mechanisms driving the magnitude and timing of a second wave of infections upon re-opening.

This work is based on Dr. Renardy's *paper in press* in the *Journal of Theoretical Biology* with coauthors:
Marisa Eisenberg, UM Complex Systems & Math (LSA) and Epidemiology (Public Health)
Denise Kirschner, UM Department of Microbiology & Immunology (Medical School)

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Livestream / Virtual Mon, 28 Sep 2020 14:00:42 -0400 2020-10-20T11:30:00-04:00 2020-10-20T13:00:00-04:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Photo of Marissa Renardy
LHS Collaboratory-LHS as a Driver of Diversity, Equity, and Inclusion (October 20, 2020 11:30am) https://events.umich.edu/event/77545 77545-19879862@events.umich.edu Event Begins: Tuesday, October 20, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Healthcare and health remain unconscionably inequitable. This year, the disproportionate toll the COVID-19 pandemic has taken on those historically least well-served by our health system, has highlighted the pressing societal challenge of health disparities.

Beyond simply striving to do no harm, Learning Health Systems (LHSs) have the potential to serve as forces for justice in healthcare and health; indeed, they can be powerful drivers of diversity, equity, and inclusion. LHSs are anchored in multi-stakeholder consensus Core Values that explicitly incorporate principles such as inclusiveness, transparency, and accessibility. Their proximal goal is "to efficiently and equitably serve the learning needs of all participants, as well as the overall public good."

The October 2020 LHS Collaboratory will share lessons from health advocates working on the front lines to make healthcare and health more equitable. These thought leaders and do-ers will illuminate the transformative power of LHSs - and the diverse and inclusive communities of interest that are collaborating to realize them.

Moderator:
Joshua C. Rubin, JD, MBA, MPP, MPH
Program Officer, Learning Health System Initiatives, Department of Learning Health Sciences, University of Michigan

Panelists:
Luis Belén
Chief Executive Officer of the National Health IT Collaborative for the Underserved (NHIT Collaborative)

Danielle Brooks, JD
Director of Health Equity, Amerihealth Caritas

Melissa S. Creary, PhD, MPH, Assistant Professor
Department of Health Management and Policy
School of Public Health, University of Michigan

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Lecture / Discussion Sun, 27 Sep 2020 21:18:37 -0400 2020-10-20T11:30:00-04:00 2020-10-20T13:00:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory Logo puzzle pieces
CHM 19th Annual Horace W. Davenport Lecture in the Medical Humanities (October 21, 2020 10:00am) https://events.umich.edu/event/78729 78729-20113300@events.umich.edu Event Begins: Wednesday, October 21, 2020 10:00am
Location: Off Campus Location
Organized By: Center for the History of Medicine

The Center for the History of Medicine is pleased to announce its 19th Annual Horace W. Davenport Lecture in the Medical Humanities.

This year’s lecture will feature Dr. Powel Kazanjian, Professor and Chief of Infectious Diseases at the University of Michigan Medical School. Dr. Kazanjian is also Professor of History at the University of Michigan, where he teaches on the history of epidemics and the history of sexually transmitted diseases. He has written extensively about the history of AIDS, syphilis, commercial botulism, plague, and the development of bacteriology in America.

Dr. Kazanjian will deliver his lecture, “The Persistence of Contagious Diseases.” By the later 20th century, it had become common for public health officials and lay writers to envision a future in which epidemic diseases had been eliminated. The appearance of the new deadly disease that would eventually be known as AIDS in 1981, however, challenged their confident vision. The potent antiretroviral therapies (ART) introduced in 1996 enabled individuals receiving treatment to survive a full lifespan. By 2014, a global UNAIDS campaign sought to “end AIDS as a global health threat” by 2030” by maximizing the distribution of ART to infected people. The UNAIDS campaign is conceptually similar to earlier 20th century programs that sought to end syphilis by expanding specific therapy. The failure of these syphilis campaigns, together with the realization that today’s efforts to end AIDS is falling short of their 2020 milestones, however, raise uncertainties about whether the ongoing UNAIDs campaign will succeed. Socioeconomic and behavioral factors have hindered the biomedical campaigns to eliminate syphilis and AIDS. To be effective, scientific public health campaigns must also address how to rectify the socioeconomic conditions and human behaviors that vex elimination efforts and lead to emerging epidemics like AIDS and Covid-19. Epidemic diseases, along with efforts launched to contain them, have been and continue to be an inescapable part of our existence.

Please join us for this engaging and timely online lecture from one of the nation’s premiere infectious disease experts.

Thursday, November 12, 2020

3:00 pm – 4:30 pm

Zoom link: https://umich-health.zoom.us/j/93152555886

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Lecture / Discussion Wed, 21 Oct 2020 10:06:52 -0400 2020-10-21T10:00:00-04:00 2020-10-21T11:00:00-04:00 Off Campus Location Center for the History of Medicine Lecture / Discussion CHM 19th Annual Davenport Lecture
DCMB / CCMB Weekly Seminar (October 21, 2020 4:00pm) https://events.umich.edu/event/78531 78531-20058232@events.umich.edu Event Begins: Wednesday, October 21, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract
Although machine learning applications are now pervasive to every industry, adoption into healthcare remains a challenging and arduous process. Barriers to implementation include clinician trust, algorithm credibility and actionability, promoting clinician literacy in machine learning methods, and mitigating unintended consequences.

In the high-risk operating room setting, anesthesiologists are recognized leaders in patient safety, and manage uncertainty through careful considerations of risk and benefit based upon a thorough understanding of disease processes and treatment mechanisms. In this talk, the speaker highlights how obstacles to implementation of machine-learning based healthcare applications can be mitigated, and how an understanding of such applications can be promoted among clinically-minded anesthesiologists who may not necessarily be expert data scientists.

Short Bio:
Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Associate Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 14 Oct 2020 11:43:15 -0400 2020-10-21T16:00:00-04:00 2020-10-21T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Image which promotes the content of Dr. Mathis' talk (https://jamanetwork.com/collections/5584/critical-care-medicine)
Special Joint Seminar - Hosted by DCMB, Department of Mathematics, and the Smale Institute (October 26, 2020 12:00pm) https://events.umich.edu/event/78673 78673-20099541@events.umich.edu Event Begins: Monday, October 26, 2020 12:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Dr. Leland Hartwell won the Nobel Prize in Physiology or Medicine in 2001 for the discoveries of key regulators of the cell cycle.

“We want our students to have an authentic experience of science. Nearly all science activities designed for schools require the students to demonstrate an established scientific principle by getting the right answer. Getting the “right” answer is not authentic science. Science is the exploration of the unknown – the answer cannot be known.“
- Leland Hartwell

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Livestream / Virtual Mon, 19 Oct 2020 13:04:27 -0400 2020-10-26T12:00:00-04:00 2020-10-26T13:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Dr. Leland Hartwell, Nobel Laureate
STS Speaker. Permeability as Pathology: Leaky Gut and Other-Threatened Borders (October 26, 2020 4:00pm) https://events.umich.edu/event/77485 77485-19875781@events.umich.edu Event Begins: Monday, October 26, 2020 4:00pm
Location: Off Campus Location
Organized By: Science, Technology & Society

The Science, Technology, Medicine and Society (STeMS) Speaker Series features scholars doing research across the range of STS subject matter. This term:

Are we humans cooperative or warlike, rational or delusional, fixed or flexible? These questions have philosophical bite and political stakes. Indeed, they always have. But recent work in a range of disciplines asks us to go deeper. What if “we humans” are more fiction than fact? If we can’t assume the stability of the human across time and place, what happens to debates about human nature? Humanistic approaches, including actor-network theory, posthuman criticism, and multispecies ethnographies, challenge the idea of an autonomous human nature, while scientific studies of organ development, neuroendocrinology, and the microbiome are revealing how much nature there is inside of us. We explore these questions through a braided history of the human and environmental sciences.

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Lecture / Discussion Wed, 14 Oct 2020 09:44:33 -0400 2020-10-26T16:00:00-04:00 2020-10-26T17:30:00-04:00 Off Campus Location Science, Technology & Society Lecture / Discussion Dr. Nitin Ahuja
Analyzing the Value of Flexibility in Design & Operations of Outpatient Health Centers (October 26, 2020 4:30pm) https://events.umich.edu/event/78742 78742-20115266@events.umich.edu Event Begins: Monday, October 26, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Although it is understood that healthcare systems are complex and dynamic systems, many times the operations of these systems, particularly around the allocation of fixed resources and physical space, is treated as fixed or static. As such policies regarding (i) the flow of patients, (ii) allocation of exam rooms, or (iii) the assignment of medical assistants to physicians are set at the beginning of the day, week or month, and remain unchanged across that duration. While the static nature of these schemes are meant to support stability and reduced complexity in the operations, this fixed mindset can hinder the ability to drive quality improvement. This presentation will review applications of simulation modeling in support of assessing the value that can be obtained from integrating flexibility into operational policies. We will review dynamic room allocation policies and staffing policies as applied to a crowded cardiovascular clinic. Additionally, we will explore similar concepts in multiple orthopedic clinics. Finally, we will present how these concepts can be similarly examined with a continuous-time Markov model.

Jackie Griffin is an Associate Professor in the Mechanical and Industrial Engineering Department at Northeastern University. Her research focuses on applications of Operations Research, Optimization, and Simulation methodologies in designing, managing and operating resilient healthcare delivery systems, ranging from outpatient clinics to regional emergency response networks to global pharmaceutical supply chains. Currently she leads a National Science Foundation funded project focused on tackling the ongoing challenge of drug shortages in the United States through the analysis of analytical models of pharmaceutical supply chains. Additionally, she has partnered with many prominent healthcare organizations to examine new strategies for improving the design and operation of health care systems while accounting for the need to balance multiple system objectives in ensuring delivery of high quality health care services. Her recent collaborations include organizations such as Massachusetts General Hospital, Tufts Medical Center, Boston Children’s Hospital, Beth Israel Hospital, Brigham and Women’s Hospital, and the IQVIA Institute for Human Data Science. Other past collaborators include the Centers for Disease Control and Prevention (CDC), Children’s Healthcare of Atlanta, DeKalb Medical Women’s Center, Emory University Hospital, Grady Memorial Hospital, and World Vision International. She received her PhD from the H. Milton Stewart School of Industrial and Systems Engineering at Georgia Institute of Technology. Additionally, she completed her MS and BS degrees in the Industrial and Systems Engineering department at Lehigh University.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 21 Oct 2020 17:19:55 -0400 2020-10-26T16:30:00-04:00 2020-10-26T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Jackie Griffin, Ph.D.
DCMB / CCMB Seminar (October 28, 2020 4:00pm) https://events.umich.edu/event/78528 78528-20058229@events.umich.edu Event Begins: Wednesday, October 28, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Single-cell RNA sequencing (scRNA-seq) allows researchers to examine the transcriptome at the single-cell resolution and has been increasingly employed as technologies continue to advance. Due to technical and biological reasons unique to scRNA-seq data, clustering and batch effect correction are almost indispensable to ensure valid and powerful data analysis. Multiple methods have been proposed for these two important tasks. For clustering, we have found that different methods, including state-of-the-art methods such as Seurat, SC3, CIDR, SIMLR, t-SNE + k-means, yield varying results in terms of both the number of clusters and actual cluster assignments. We have developed ensemble methods, SAFE-clustering and SAME-clustering, that leverages hyper-graph partitioning algorithms and a mixture model-based approach respectively to produce more robust and accurate ensemble solution on top of clustering results from individual methods. For batch effect correction, we have developed methods based on supervised mutual nearest neighbor detection to harness the power of known cell type labels for certain single cells. We benchmarked all methods in various scRNA-seq datasets to demonstrate their utilities.

Short bio: Yun Li, PhD is an Associate professor of Genetics and Biostatistics at the University of North Carolina, Chapel Hill. Dr. Li is a statistical geneticist with extensive experiences with method development and application on genotype imputation (developer of MaCH and MaCH-admix), genetic studies of recently admixed population, design and analysis of sequencing-based studies, analyses of multi-omics data including mRNA expression, DNA methylation and chromatin three dimensional organization. Dr. Li has been playing an active role in genetic studies of complex human traits resulting many GWAS and meta-analysis publications, including >30 in Nature, Science, Cell, and Nature Genetics. Dr. Li has been leading multiple R01 projects on statistical method development for complex trait genetics. Dr. Li has also been the Director for the Data Science Core of IDDRC (Intellectual and Developmental Disabilities Research Center). Dr. Li has received many awards and became the Thomson Reuters Highly Cited Researcher due to her high impact scientific work. Specifically, her work has been cited >60,000 times with h-index of 64 and i10-index of 113.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 14 Oct 2020 10:41:20 -0400 2020-10-28T16:00:00-04:00 2020-10-28T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Yun Li, PhD (Associate Professor of Genetics & Biostatistics; Adjunct Associate Professor, Applied Physical Sciences at School of Medicine, Genetics at University of North Carolina)
Data Science and Global Health Equity Seminar (October 29, 2020 5:00pm) https://events.umich.edu/event/78430 78430-20042434@events.umich.edu Event Begins: Thursday, October 29, 2020 5:00pm
Location: Off Campus Location
Organized By: Center for Global Health Equity

Please join us for the Center for Global Health Equity's seminar on Data Science. Panelists include:
Akbar Waljee (Medicine)
Bhramar Mukherjee (SPH)
Andries Coetzee (LSA)
Massy Mutumba (Nursing)
Gifty Kwakye (Medicine)
Moderated by John Ayanian

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Workshop / Seminar Mon, 12 Oct 2020 11:49:29 -0400 2020-10-29T17:00:00-04:00 2020-10-29T18:30:00-04:00 Off Campus Location Center for Global Health Equity Workshop / Seminar Seminar Panelists
"African-American Health Disparities and Moving Towards a Beloved Community in Health Care" (October 30, 2020 12:00pm) https://events.umich.edu/event/78526 78526-20058227@events.umich.edu Event Begins: Friday, October 30, 2020 12:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

The Woll Family Speaker Series on Health, Spirituality and Religion presents Patrick T. Smith, BS, MDiv, MA, PhD, Duke University

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Workshop / Seminar Wed, 14 Oct 2020 10:08:53 -0400 2020-10-30T12:00:00-04:00 2020-10-30T13:00:00-04:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar
Be a Hero at the Big House (November 1, 2020 8:00am) https://events.umich.edu/event/78304 78304-20004863@events.umich.edu Event Begins: Sunday, November 1, 2020 8:00am
Location:
Organized By: Wolverines for Life

Join us for our largest event of the year. In consideration of the pandemic, we'll be converting this event to a hybrid virtual/in-person experience. Keep an eye on our website for more information about the day's online entertainment. Due to last-minute changes to the football schedule, we’ve moved the blood drive to two locations in Ann Arbor: the Kensington Hotel near Briarwood Mall and the Graduate Ann Arbor downtown.

Blood donors are encouraged to donate blood at the biggest blood drive in Southeast Michigan. Blood donations will count towards the Blood Battle competition against OSU. Attendees also have the opportunity to join the organ donor registry or be screened as a bone marrow donor. There will be virtual entertainment, activities, giveaways, special guests, and more throughout the day. More information coming soon.



Make an appointment to donate blood at redcrossblood.org using sponsor code "goblue". For information about the Red Cross’ safety protocols during the pandemic, click here(link is external).

Can't make it to Be a Hero? Schedule a blood drive appointment between 10/28/2020 and 11/25/2020 to help us beat OSU in the annual Blood Battle competition! Visit www.redcrossblood.org(link is external) and enter promo code "goblue."



Interested in volunteering at Be a Hero? Click here to sign up!(link is external)

Interested in sharing your donation/transplant story at the event? Contact Megan Podschlne at mpodschl@med.umich(link sends e-mail).edu(link sends e-mail) with a brief synopsis.

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Other Wed, 07 Oct 2020 16:56:24 -0400 2020-11-01T08:00:00-05:00 2020-11-01T17:00:00-05:00 Wolverines for Life Other Be a Hero 2020 flyer
Rightsizing Prenatal Care: Tailoring Prenatal Services to Match Patients’ Needs (November 2, 2020 5:30pm) https://events.umich.edu/event/78743 78743-20115267@events.umich.edu Event Begins: Monday, November 2, 2020 5:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Please note the seminar starts at 5:30 PM EST, an hour later than our usual seminar time.

Each year, nearly 4 million women who give birth in the United States receive prenatal care—a crucial preventive service that improves pregnancy outcomes for mothers and their children. National guidelines currently recommend 12 to 14 in-person prenatal visits for all patients regardless of medical or social needs. This schedule recommends more care for low-risk women than peer countries with better outcomes that the U.S., and has remained unchanged since 1930, failing to adapt to the needs of modern patients. Current prenatal care has also failed to address significant inequities in maternity care: low-income and black patients less likely to receive recommended services before delivery, and are more likely to suffer from severe maternal morbidity and mortality in pregnancy.

Although we know that prenatal care services (e.g. laboratory tests and vaccinations) are evidence based, these evidence-based services can be delivered in fewer than 14 visits. There is also evidence that patients do not need to visit clinics in person to receive all maternity services. This schedule results in overutilization of care for low-risk pregnant patients, and potential access issues for patients with more intense needs in pregnancy. In this talk, we will review the evidence supporting prenatal care and new delivery models. We will then introduce a new conceptual model for redesigning prenatal care to meet patients’ diverse medical and social needs, and demonstrate how this model can be used to test new models of prenatal care to drive appropriate resource allocation. We will conclude with early findings from new models that were launched during the COVID-19 pandemic with a focus on ensuring new prenatal care delivery is effective, efficient and equitable.

Dr. Alex Peahl is an Obstetrician Gynecologist and physician-investigator in the Department of Obstetrics and Gynecology at the University of Michigan. Her research focuses on how to improve the effectiveness, efficiency and equity of reproductive health care through developing, studying and disseminating high-quality maternity care interventions. She is a nationally recognized expert on prenatal care redesign and innovation and has completed seminal studies and thought pieces on how to best incorporate patients’ preferences and needs into rightsized prenatal care plans: plans that match patients’ needs to services delivered. She is the research lead for prenatal care redesign at the University of Michigan, and new guidelines driven by her team were recognized by the American College of Obstetricians and Gynecologists as the example for nationwide practice during the COVID-19 pandemic. She is currently leading the Michigan Plan for Appropriate, Tailored Healthcare in Pregnancy, a national consensus process to develop new prenatal care guidelines in pregnancy.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 21 Oct 2020 17:28:03 -0400 2020-11-02T17:30:00-05:00 2020-11-02T18:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Alex Peahl, MD, MSc
DCMB / CCMB Weekly Seminar (November 4, 2020 4:00pm) https://events.umich.edu/event/78770 78770-20121164@events.umich.edu Event Begins: Wednesday, November 4, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Metabolomics is a powerful approach to characterize small molecules produced in cells, tissues, and other biological systems. Metabolites are direct products of enzymatic reactions and provide a snapshot of cellular activities. Metabolomics-based research has already had a profound impact on biomarker discovery, nutritional analysis, and other biomedical and biological discoveries. The most pressing problem in metabolomics however is identifying compounds in the sample-under-study from the metabolomics measurements. Current analysis tools are capable of annotating only a small portion of sample measurements.

In this talk, we present machine learning solutions to three challenges related to the interpretation of metabolomics data. To mimic the function of a mass spectrometer in generating a mass spectrum, we use graph neural networks to translate a molecular structure into its respective spectral signature. To interpret the biological measurements in the context of the biological sample, we use Bayesan learning to deduce the likelihood of pathway activities. To suggest putative candidate molecules that are biologically relevant matches to the measured spectra, we explore several methods for predicting possible enzymatic products. We discuss several results, highlighting the value of using machine learning for advancing metabolomics analysis.

Short bio: Soha Hassoun is Professor and Past Chair of the Department of Computer Science at Tufts University. Soha received her undergraduate degree in Electrical Engineering from South Dakota State University, the Master's degree from MIT, and the Ph.D. degree from the Department of Computer Science and Engineering, University of Washington in Seattle. Soha’s lab uses Machine Learning to develop analysis and discovery tools for synthetic and systems biology, with a focus on enzyme promiscuity prediction and metabolomics analysis. Soha was a recipient of the NSF CAREER Award, and several technical and service awards from various professional societies. She provided technical leadership for several conferences including ICCAD and DAC. She co-founded the International Workshop on Bio-Design Automation in 2009. Soha serves on the board of the Computing Research Association's Committee on Widening Participation in Computing Research.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 22 Oct 2020 11:33:23 -0400 2020-11-04T16:00:00-05:00 2020-11-04T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Clinical Simulation Center Brown Bag Series (November 5, 2020 11:00am) https://events.umich.edu/event/79224 79224-20231467@events.umich.edu Event Begins: Thursday, November 5, 2020 11:00am
Location:
Organized By: Clinical Simulation Center

Dr. Munzer is a Clinical Lecturer, in the Department of Emergency Medicine at Michigan Medicine. He joined the University’s Medical Education Fellowship after completing his training in Emergency Medicine with the University of Michigan/St. Joseph Mercy Hospital Residency Program.

He will give an update on the Extracorporeal Membrane Oxygenation (ECMO) training and simulation program, including the new simulator in the Clinical Simulation Center, as well the goals of the program.

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Lecture / Discussion Thu, 05 Nov 2020 11:34:01 -0500 2020-11-05T11:00:00-05:00 2020-11-05T12:00:00-05:00 Clinical Simulation Center Lecture / Discussion Extracorporeal Membrane Oxygenation (ECMO)
Veterans Week: Lessons learned from military service and how it can help in the era of COVID 19 (November 9, 2020 12:00pm) https://events.umich.edu/event/79010 79010-20170607@events.umich.edu Event Begins: Monday, November 9, 2020 12:00pm
Location: Off Campus Location
Organized By: Veteran and Military Services

Military Healthcare has had a strong relationship with civilian health care for many years. They say that “Necessity is the mother of invention.” Overtime military research and innovations have been adopted into civilian medicine. For the last 8 months our national health system has been dealing with the challenges of COVID-19. Unlike a “normal” mass casualty event, the COVID-19 pandemic poses unique challenges to the health system and to the execution of health care. As a military veteran I was able to use and apply many lessons learned and leadership concepts from my military background to my experience at Swedish Edmonds Hospital.

This presentation will cover topics such as: Planning, Training, Human Factors, Concept of Mission Command, Logistics and Personnel.
Additional topics will be discussed as time allows.

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Lecture / Discussion Wed, 28 Oct 2020 16:12:50 -0400 2020-11-09T12:00:00-05:00 2020-11-09T13:00:00-05:00 Off Campus Location Veteran and Military Services Lecture / Discussion Destist student. #dorinabeqiraj
Veterans Week: Stories from the front lines of a disaster; a military healthcare perspective (November 9, 2020 6:30pm) https://events.umich.edu/event/78739 78739-20115261@events.umich.edu Event Begins: Monday, November 9, 2020 6:30pm
Location: Off Campus Location
Organized By: Veteran and Military Services

As COVID-19 continues to challenge our school, our nation, and our world, it is important to consider the strength and support that can come from our community members sharing their diverse personal and professional experiences. Join us as University of Michigan School of Nursing military alumni discuss ways in which we can continue to move forward and overcome the pandemic. Representatives from the Navy, Air Force, and Army bring forward a broad range of stories, from Clinical Nurse Specialists currently on the front lines, to tales from a Baghdad deployment faced with tremendous adversity. Now more than ever, we are in this together, and few understand this concept of unity better than the members of our Armed Forces.

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Lecture / Discussion Wed, 28 Oct 2020 17:38:42 -0400 2020-11-09T18:30:00-05:00 2020-11-09T19:30:00-05:00 Off Campus Location Veteran and Military Services Lecture / Discussion Biomedical engineer develops blood filtering treatment
Of Moms and Microbes: Pregnancy and the Microbiome (November 10, 2020 12:00pm) https://events.umich.edu/event/79039 79039-20178452@events.umich.edu Event Begins: Tuesday, November 10, 2020 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Kimberly McKee, PhD, Assistant Professor of Family Medicine at the UM Medical School will present a seminar, with Q&A, on "Of Moms and Microbes: Pregnancy and the Microbiome".

ZOOM link:
https://umich.zoom.us/j/97328685723

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Lecture / Discussion Thu, 29 Oct 2020 13:13:13 -0400 2020-11-10T12:00:00-05:00 2020-11-10T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Environmental Research Seminar
Bioethics Discussion: Democracy (November 10, 2020 5:00pm) https://events.umich.edu/event/58831 58831-14563723@events.umich.edu Event Begins: Tuesday, November 10, 2020 5:00pm
Location: Lurie Biomedical Engineering
Organized By: The Bioethics Discussion Group

A discussion we will choose to have.

A few readings to consider on the matter:
––Bioethics and Democracy
––Bioethics and Populism: How Should Our Field Respond?
––Crowdsourcing in medical research: concepts and applications
––How Democracy Can Inform Consent: Cases of the Internet and Bioethics

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/050-democracy/.

––

While people are still allowed on campus, discussions will be held on the front lawn of Lurie Biomedical Engineering building. Participants will be asked to enter the area via a “welcome desk” where there will be hand sanitizer, wipes, etc. Participants will be masked, at least 12 feet from one another, and speaking through megaphones with one another. In accordance with public health mandates and guidance, participation will be limited to 20 individuals who sign up to participate ahead of time.

Sign up here: https://belmont.bme.umich.edu/ask-your-questions-to-ponder/

––
Together, we can read the blog (and probably do much more than that): https://belmont.bme.umich.edu/incidental-art/

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Lecture / Discussion Tue, 10 Nov 2020 16:24:01 -0500 2020-11-10T17:00:00-05:00 2020-11-10T18:30:00-05:00 Lurie Biomedical Engineering The Bioethics Discussion Group Lecture / Discussion Image 050. Democracy
Veterans Week: Michigan Medicine Veteran Panel (November 10, 2020 6:30pm) https://events.umich.edu/event/78623 78623-20075979@events.umich.edu Event Begins: Tuesday, November 10, 2020 6:30pm
Location: Off Campus Location
Organized By: Veteran and Military Services

The military can prepare many people for a career in medicine and in the healthcare field. Michigan Medicine employees over 400 veterans. Hear the experiences of these professionals as they discuss their experiences both in service and as veterans.

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Lecture / Discussion Fri, 16 Oct 2020 16:54:20 -0400 2020-11-10T18:30:00-05:00 2020-11-10T19:30:00-05:00 Off Campus Location Veteran and Military Services Lecture / Discussion Doctor with a stethoscope
Honors Grand Rounds with Xiao Wang, MD (November 10, 2020 7:00pm) https://events.umich.edu/event/76327 76327-19687520@events.umich.edu Event Begins: Tuesday, November 10, 2020 7:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

Join Stephanie Chervin, Honors premed advisor, for a virtual live discussion with Honors alum Xiao Wang, MD; internal medicine University of Pennsylvania Health System. This program is for current LSA Honors Program students only. A link to the virtual event will be sent to all registrants before the event.

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Presentation Fri, 28 Aug 2020 15:47:52 -0400 2020-11-10T19:00:00-05:00 2020-11-10T20:00:00-05:00 Off Campus Location LSA Honors Program Presentation Dr. Wang at Hopkins graduation
DCMB / CCMB Weekly Seminar (November 11, 2020 4:00pm) https://events.umich.edu/event/79286 79286-20264787@events.umich.edu Event Begins: Wednesday, November 11, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: There is a growing understanding that stress and depression during the process of training to become physicians is high. In this talk, we will discuss how we have used mobile and wearable data as well as genomics to understand the prevalence in the US and China, drivers and possible solutions about training physician depression and how the COVID-19 pandemic has affected them in the two countries.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 09 Nov 2020 14:13:58 -0500 2020-11-11T16:00:00-05:00 2020-11-11T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Drs. Margit Burmeister and Srijan Sen
"Weight of Honor" Film Discussion and Panel (November 12, 2020 12:00pm) https://events.umich.edu/event/78642 78642-20077958@events.umich.edu Event Begins: Thursday, November 12, 2020 12:00pm
Location: Off Campus Location
Organized By: Veteran and Military Services

“The Weight of Honor” is the first comprehensive documentary to chronicle the lives of families caring for their
catastrophically wounded returning from wars in Iraq and Afghanistan. Over the course of five years, the film follows the arc of what
happens when some of America's best and strongest volunteer to protect our nation, but return home physically and emotionally
broken and disillusioned. What happens when they return is not only a personal journey but also that of their family caregivers who
have no training other than the love for their wounded. Our military does not prepare families for the return of a wounded warrior.
“The Weight of Honor” tells their stories of strength, exhaustion, conflict, and even humor as they chart a course through the
unknown

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Lecture / Discussion Sun, 08 Nov 2020 17:27:11 -0500 2020-11-12T12:00:00-05:00 2020-11-12T13:00:00-05:00 Off Campus Location Veteran and Military Services Lecture / Discussion Weight of Honor Movie Poster
A New Perspective on Amelogenesis and Dental Diagnoses (November 12, 2020 12:00pm) https://events.umich.edu/event/79191 79191-20225570@events.umich.edu Event Begins: Thursday, November 12, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

James P. Simmer, DDS, PhD Professor of Dentistry
Biologic and Materials Sciences & Prosthodontics
University of Michigan School of Dentistry

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Lecture / Discussion Wed, 04 Nov 2020 15:24:08 -0500 2020-11-12T12:00:00-05:00 2020-11-12T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Simmer
Reflections on Learning to Improve: Foundational Ideas, Observations from Practice, and Building a Field (November 12, 2020 12:00pm) https://events.umich.edu/event/78908 78908-20152763@events.umich.edu Event Begins: Thursday, November 12, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

While the LHS Collaboratory is typically focused on learning health, learning systems actually have very broad applicability. Moreover, there has been a strong interest in the Collaboratory from the education community which is also focused on learning systems.

A thought leader in this area, Anthony S. Bryk, President of the Carnegie Foundation for the Advancement of Teaching, will be speaking about a set of critical observations acquired in the course of his own efforts to improve how large complex educational systems work.

Discussants:

Elizabeth Birr Moje, Dean,
George Herbert Mead Collegiate Professor of Education,
and Arthur F. Thurnau Professor School of Education
Faculty Associate in the Institute for Social Research; Latino/a
Studies; and the Joint Program in English & Education
University of Michigan

Caren M. Stalburg, MD, MA
Collaborative Lead for Education
Associate Professor of Learning Health Sciences
Associate Professor of Obstetrics and Gynecology
Director of HILS Online Masters
University of Michigan

Moderator:

Donald J. Peurach, PhD
Professor
University of Michigan School of Education
Senior Fellow, Carnegie Foundation for the Advancement of
Teaching

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Lecture / Discussion Mon, 26 Oct 2020 12:41:04 -0400 2020-11-12T12:00:00-05:00 2020-11-12T13:30:00-05:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Collaboratory logo
The Persistence of Contagious Diseases: The Davenport Lecture in Medical Humanities (November 12, 2020 3:00pm) https://events.umich.edu/event/79267 79267-20262816@events.umich.edu Event Begins: Thursday, November 12, 2020 3:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

Epidemic diseases, and efforts to contain them, have been and continue to be an inescapable part of human existence. Dr. Powel Kazanjian, chief of infectious diseases at Michigan Medicine and a professor of history and public health, will trace these efforts, including similarities between efforts to contain syphilis in the early 20th Century and HIV/AIDS in the latter part of the century, as well as COVID-19 in 2020.

He'll also explore why scientific public health campaigns must also address how to rectify the socioeconomic conditions and human behaviors that vex elimination efforts and lead to emerging epidemics.

The lecture is the 19th annual Horace W. Davenport Lecture in the Medical Humanities, presented by the U-M Medical School's Center for the History of Medicine.

Full details and a Zoom link to watch the lecture are at https://chm.med.umich.edu/chms-19th-annual-davenport-lecture-nov-12-2020/

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Lecture / Discussion Mon, 09 Nov 2020 10:54:33 -0500 2020-11-12T15:00:00-05:00 2020-11-12T16:00:00-05:00 Off Campus Location Michigan Medicine Lecture / Discussion Persistence of Contagious Diseases
Clinical Simulation Center Brown Bag Series (November 16, 2020 12:00pm) https://events.umich.edu/event/79218 79218-20231461@events.umich.edu Event Begins: Monday, November 16, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

This talk will cover the basic elements of using simulation for non-technical skills. We will review some validated frameworks for assessing these “soft” skills, including NOTSS (Nontechnical Skills for Surgeons) and ANTS (Anaesthetistis’ Non-technical Skills), discuss unique concerns regarding writing learning objectives for these skills, and review some recently completed non-technical simulations from the Department of Surgery.

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Meeting Thu, 05 Nov 2020 11:14:45 -0500 2020-11-16T12:00:00-05:00 2020-11-16T13:00:00-05:00 Off Campus Location Department of Learning Health Sciences Meeting Laura Mazer, MD MHPE
RNA Seminar featuring: Michelle Hastings, Professor, Rosalind Franklin University of Medicine and Science (November 16, 2020 4:00pm) https://events.umich.edu/event/75868 75868-19615934@events.umich.edu Event Begins: Monday, November 16, 2020 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

https://umich.zoom.us/webinar/register/WN_VWX5SY6lSiaNyh5Weh8cHw

Michelle L. Hastings, PhD
Professor, Cell Biology and Anatomy
Director, Center for Genetic Diseases
Rosalind Franklin University of Medicine and Science

ABSTRACT: Antisense oligonucleotides (ASOs) have proven to be an effective therapeutic platform for the treatment of disease. These short, single-stranded, modified nucleotides function by base-pairing with the complementary sequence of an RNA and modulating gene expression in a manner that is dependent on the ASO design and targeting site. We have used ASOs to normalize aberrant gene expression associated with a number of diseases of the nervous system including Alzheimer’s and Parkinson’s disease and Usher syndrome. One of our approaches is under development for the treatment of CLN3 Batten disease, a fatal, pediatric lysosomal storage disease caused by mutations in a gene encoding the lysosomal membrane protein CLN3. The most common mutation associated with CLN3 Batten is a deletion of exons 7 and 8 (CLN3Δex78), which disrupts the mRNA open reading frame by creating a premature termination codon that results in the production of a truncated protein. We devised a therapeutic strategy for treating CLN3 Batten Disease using an ASO that basepairs to CLN3 pre-mRNA and alters splicing to correct the open reading frame of the mutated transcript. Treatment of CLN3Δex78 neonatal mice by intracerebroventricular injection of the ASO resulted in the desired splicing effect throughout the central nervous system, improved motor deficits associated with the disease in mice, reduced histopathological features of the disease in the brain and extended life in a severe mouse model of the disease. Our results demonstrate that ASO-mediated reading frame correction is a promising therapeutic approach for CLN3 Batten disease.

KEYWORDS: pre-mRNA splicing, Antisense oligonucleotides, Usher syndrome, Batten Disease, lysosomal storage diseases

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Lecture / Discussion Wed, 07 Oct 2020 09:31:00 -0400 2020-11-16T16:00:00-05:00 2020-11-16T17:00:00-05:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion photo
Optimal Influenza Vaccine Distribution With Equity (November 16, 2020 4:30pm) https://events.umich.edu/event/79331 79331-20272794@events.umich.edu Event Begins: Monday, November 16, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Influenza is a serious public health concern. Each year 5-15% of the world’s population is infected with influenza resulting in 3-5 million severe cases and 250,000-500,000 deaths. This presentation is concerned with the optimal influenza vaccine distribution in a heterogeneous population consisting of multiple subgroups. In our experiments, each subgroup corresponds to a set of people within an age group living in a certain geographic area, however the definition of subgroup is flexible. For example, healthcare workers or nursing home residents can be considered as subgroups in real life policy decisions. To characterize the spread of influenza through interacting subgroups, we employ an epidemic model that incorporates transmission dynamics and social distancing. The epidemic model is then coupled with a nonlinear mathematical program to find the critical vaccine allocation that minimizes vaccine usage. We also include an equity constraint to help public health authorities find a balanced vaccine allocation policy with respect to equity and effectiveness. Several detailed epidemic simulation models are developed in the literature to evaluate vaccination policies before their implementation so as to efficiently allocate resources. This study goes beyond evaluating a given vaccine allocation policy. The proposed approach can be utilized as a decision support tool to prescribe an equitable vaccine allocation policy to extinguish an emerging outbreak in its early stages. Furthermore, the optimal objective function value of our model can inform public health authorities about the amount of vaccine stockpiles needed to stop future outbreaks. Our results indicate that consideration of group-specific transmission dynamics is paramount to the optimal distribution of influenza vaccines.

Shakiba Enayati is an Assistant Professor in Supply Chain and Analytics Department in the College of Business Administration at the University of Missouri- Saint Louis. She earned her Ph.D. in Operations Research Program from North Carolina State University in May 2017. She also holds a Master of Science and a Bachelor in Industrial Engineering from Tarbiat Modares University and Iran University of Science and Technology in Tehran, Iran. She was previously employed as Assistant Professor of Analytics in Management, Information Systems, and Analytics Department at State University of New York, Plattsburgh. Shakiba’s primary research interests are in analytical modeling and optimization of stochastic/dynamic complex systems as applied to healthcare and service systems. Her goal is to address computational and operational aspects of problems arising in public health policy making, health systems management, and medical decision making via incorporating individual patient data. She is also interested in predictive analytics to evaluate, anticipate, and recommend actions for health outcomes at both individual and system levels. Her Ph.D. dissertation focused on service quality improvement and optimally allocating resources in the dynamic and stochastic environment of Emergency Medical Service systems under realistic operational restrictions.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Tue, 10 Nov 2020 16:00:42 -0500 2020-11-16T16:30:00-05:00 2020-11-16T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Shakiba Enayati, Ph.D.
The Lasting Impact of Covid-19 -- Pandemic Update: Vaccines, Testing and Treatments (November 17, 2020 10:00am) https://events.umich.edu/event/75656 75656-19552876@events.umich.edu Event Begins: Tuesday, November 17, 2020 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

This event is free and available to the public. OLLI membership is not required.

In her follow-up to her talk to OLLI in May, Dr. Martin will explore what we’ve learned during the first nine months of the COVID-19 epidemic and how recent scientific advances have impacted the vaccine and antiviral landscape.

Dr. Emily Toth Martin is on the faculty of Epidemiology at the University of Michigan School of Public Health. Her research focuses on building a greater understanding of the epidemiology of viral respiratory diseases (including RSV, bocavirus, and influenza) through the use of molecular epidemiology. In particular, her work aims to identify strategies to reduce infections, particularly in individuals with chronic comorbidities and in hospital infectious environments (including MRSA / VRE coinfection).

Zoom Link to join this programming:
https:// umich.zoom.us/j/95090096277
Webinar ID: 95090096277

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Class / Instruction Tue, 11 Aug 2020 17:22:52 -0400 2020-11-17T10:00:00-05:00 2020-11-17T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Urgent and Critical Lectures
DCMB / CCMB Weekly Seminar (November 18, 2020 4:00pm) https://events.umich.edu/event/79290 79290-20264791@events.umich.edu Event Begins: Wednesday, November 18, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Genetic variation affecting gene expression is wide-spread within and among species. This variation reflects the combined actions of mutation introducing new genetic variants and selection eliminating deleterious ones. Comparative studies of gene expression in fruit flies, yeast, plants, and mice have shown that the relative contributions of cis- and trans-acting variants to expression differences change over evolutionary time, indicating that selection has different effects on cis- and trans-regulatory variants. To better understand the reasons for this now widely observed pattern, we have been systematically studying the effects of mutation and selection on expression of the TDH3 gene of the baker’s yeast Saccharomyces cerevisiae. This work has revealed differences between cis- and trans-regulatory mutations in their frequency, effects, and dominance. Differences in pleiotropy are also generally assumed to exist between cis- and trans-regulatory that affect their evolutionary fate, but have been difficult to measure. In this talk, I will discuss how newly arising cis- and trans-regulatory mutations affecting expression of this focal gene are structured within the regulatory network, their pleiotropic effects on expression of all other genes in the genome, and how these pleiotropic effects influence fitness. A computational model of regulatory evolution integrating empirically observed differences in properties of cis- and trans-regulatory mutations will also be presented and discussed.

Patricia Wittkopp received a BS from the University of Michigan, a PhD from the University of Wisconsin, and did postdoctoral work at Cornell University. In 2005, she began a faculty position at the University of Michigan, where she is now the Sally L. Allen Collegiate Professor and Arthur F Thurnau Professor in the Department of Ecology and Evolutionary Biology and the Department of Molecular, Cellular, and Developmental Biology, and is a member of the Center for Computational Medicine and Bioinformatics. Her research investigates the genetic basis of phenotypic evolution, with an emphasis on the evolution of gene expression. She was a Damon Runyon Cancer Research Fellow, an Alfred P Sloan Research Fellow, Guggenheim Fellow, and a recipient of a March of Dimes Starter Scholar Award, the Margaret Dayhoff Mid-Career Award from the Society of Molecular Biology and Evolution, and the Friedrich Wilhelm Bessel Research Award from the Alexander von Humboldt Foundation.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 09 Nov 2020 15:12:34 -0500 2020-11-18T16:00:00-05:00 2020-11-18T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Chemosensory pathways involved in periodontitis and odontogenic pain (November 19, 2020 12:00pm) https://events.umich.edu/event/79190 79190-20225569@events.umich.edu Event Begins: Thursday, November 19, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Marco Tizzano, PhD
Assistant Member, Monell Chemical Senses Center
Adjunct Assistant Professor, Basic & Translational Sciences - Penn Dental Medicine

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Lecture / Discussion Wed, 04 Nov 2020 15:19:42 -0500 2020-11-19T12:00:00-05:00 2020-11-19T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Tizzano
Where Do We Go From Here: Body Politics & Movement Towards Racial Empowerment (November 19, 2020 12:00pm) https://events.umich.edu/event/79333 79333-20272796@events.umich.edu Event Begins: Thursday, November 19, 2020 12:00pm
Location: Off Campus Location
Organized By: School of Kinesiology

A virtual panel discussion sponsored by the University of Michigan Health Sciences units, hosted by the School of Kinesiology, and featuring:

Vanessa Barrow, DPM
Podiatrist & Owner, Sole Aesthetic, LLC
Specialization: Aesthetic and regenerative medicine of the foot and ankle

Neha Gothe, PhD
Assistant Professor of Kinesiology & Community Health, University of Illinois at Urbana-Champaign
Research: Bio-psycho-social health benefits of physical activity across the lifespan; yoga as a means to improve health and quality of life

Samuel R. Hodge, PhD
Professor of Kinesiology, Ohio State University
Research: Intersection of diversity, disability, and social justice in education and sport

NiCole R. Keith, PhD, FACSM
Professor of Kinesiology & Associate Dean, Indiana University School of Health & Human Sciences
President, American College of Sports Medicine
Research: Community-based participatory research, physical activity, and health equity

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Lecture / Discussion Tue, 10 Nov 2020 17:05:27 -0500 2020-11-19T12:00:00-05:00 2020-11-19T13:00:00-05:00 Off Campus Location School of Kinesiology Lecture / Discussion University of Michigan Health Sciences present Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment
Empowering Women and Communities and Global Health Equity (November 19, 2020 5:00pm) https://events.umich.edu/event/79254 79254-20241308@events.umich.edu Event Begins: Thursday, November 19, 2020 5:00pm
Location: Off Campus Location
Organized By: Center for Global Health Equity

Please join us for the next seminar in the Center for Global Health's series: Empowering Women and Communities and Global Health Equity.
Panelists include:
Cheryl Moyer, Medicine
Laura Rozek, School of Public Health
Jodi Lori, Nursing
Elizabeth King, School of Public Health
Bridgette Carr, Law

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Workshop / Seminar Fri, 06 Nov 2020 13:09:26 -0500 2020-11-19T17:00:00-05:00 2020-11-19T18:30:00-05:00 Off Campus Location Center for Global Health Equity Workshop / Seminar Event Flyer
Empowering Women in Global Health (November 19, 2020 5:00pm) https://events.umich.edu/event/79418 79418-20317947@events.umich.edu Event Begins: Thursday, November 19, 2020 5:00pm
Location: Off Campus Location
Organized By: UMMS Global REACH

Women comprise about 70% of the total health workforce worldwide, but make up only 25% of health leadership positions. Empowering women and communities is one of four thematic areas leaders have identified as a focus of the new Center for Global Health Equity. Presenters Laura Rosek, from the School of Public Health, and Cheryl Moyer, from the Medical School, will lead a discussion on how U-M colleagues could partner to make an impact in this space.

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Livestream / Virtual Mon, 16 Nov 2020 11:58:32 -0500 2020-11-19T17:00:00-05:00 2020-11-19T18:30:00-05:00 Off Campus Location UMMS Global REACH Livestream / Virtual Empowering women in global health
Marie Hartwig Research Presentation (November 20, 2020 12:00pm) https://events.umich.edu/event/79391 79391-20294469@events.umich.edu Event Begins: Friday, November 20, 2020 12:00pm
Location: Off Campus Location
Organized By: School of Kinesiology

Join us for the 2020 Marie Hartwig Research Presentation:

EXERCISE AND CANCER—IS THERE A TELOMERE CONNECTION?

Presented by:
Andrew Ludlow, PhD
Assistant Professor, Movement Science
Director, Integrative Molecular Genetics Laboratory
University of Michigan School of Kinesiology

Friday, November 20
Noon–1:00PM
via Zoom at umich.zoom.us/j/99592033267 (No RSVP needed)

Abstract: In this presentation, I will focus on how exercise impacts two cellular biomarkers of aging, telomere length and telomerase enzyme activity. Telomere length and telomerase enzyme activity also have critical roles in cancer. We will explore data showing that exercise can activate telomerase in both rodents and humans, resulting in telomere length maintenance, and therefore potentially providing a mechanism of how exercise slows the aging process and reduces the risk of certain cancers. How telomerase is regulated in human stem cells, dysregulated in human lung cancers, and our future research directions will also be discussed.

Event flyer: myumi.ch/gjVB8

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Lecture / Discussion Fri, 13 Nov 2020 09:41:06 -0500 2020-11-20T12:00:00-05:00 2020-11-20T13:00:00-05:00 Off Campus Location School of Kinesiology Lecture / Discussion Hartwig Presentation 11/20/20
Impact of COVID-19 on Service Workers: Work Experiences & Concerns of food retail, food services, and hospitality workers (November 24, 2020 12:00pm) https://events.umich.edu/event/79384 79384-20288598@events.umich.edu Event Begins: Tuesday, November 24, 2020 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Marie-Anne Rosemberg is an assistant professor in UM's School of Nursing.
ABSTRACT
Objectives: COVID-19 presents a unique burden specifically for workers in service industries not only because they are disproportionately at risk for contracting the virus but also because of their work-related burdens. We aimed to understand the impact of COVID-19 on these workers.
Methods: This was a mixed-method study with a congruent triangulation design. Participants were recruited through social media. Each interview lasted up to 20 minutes. The survey data included demographic questions along with items from the CAGE and PC-PTSD questionnaires.
Results: Twenty-seven individuals completed audio-recorded phone interviews and 28 completed the survey. Participants were mostly women with an age range between 19 and 65. Participants worked in food retail (n=23), restaurant (n=25), and hospitality (n=7) industries. Length of time on the job ranged from two months to 25 years and 60% of the participants worked full time. Participants reported experiencing symptoms of depression and maladaptive coping. Job insecurity, change of job tasks, and work hours were the most common ways that COVID-19 affected the workers. Themes that emerged about participant’s concerns included being infected and/or unknowingly infecting others, the unknown, isolation, and work and customer demands. Constant changes relating to communication and protection measures were a major source of stress. There was discordance in the perceived level of threat of COVID-19. Most participants reported that their workplace complied with their state’s mandates for protection measures. While others reported lacking basic supplies such as soap, hand sanitizer, and masks.
Conclusions: In addition to their work experiences, COVID-19 has affected service workers at the financial, physical and mental levels. This study has implications of employers, occupational health and safety professionals and policy stakeholders.

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Lecture / Discussion Thu, 12 Nov 2020 16:33:42 -0500 2020-11-24T12:00:00-05:00 2020-11-24T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Impact of COVID-19 on Service Workers
Bioethics Discussion: The Coming Administration (November 24, 2020 7:00pm) https://events.umich.edu/event/58832 58832-14563724@events.umich.edu Event Begins: Tuesday, November 24, 2020 7:00pm
Location: Lurie Biomedical Engineering
Organized By: The Bioethics Discussion Group

A discussion on our (new?) government.

A few readings to consider:
––Three Ways to Politicize Bioethics
––Affording Obamacare
––Confronting Deep Moral Disagreement: The President’s Council on Bioethics, Moral Status, and Human Embryos
––The role of party politics in medical malpractice tort reforms

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/051-the-coming-administration/.

Please also swing by the blog: https://belmont.bme.umich.edu/incidental-art/

––
[OUR FIRST PLANNED REMOTE DISCUSSION]
While people are still allowed on campus, discussions will be held on the front lawn of Lurie Biomedical Engineering building. Participants will be asked to enter the area via a “welcome desk” where there will be hand sanitizer, wipes, etc. Participants will be masked, at least 12 feet from one another, and speaking through megaphones with one another. In accordance with public health mandates and guidance, participation will be limited to 20 individuals who sign up to participate ahead of time.

Sign up here: https://belmont.bme.umich.edu/ask-your-questions-to-ponder/

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Lecture / Discussion Tue, 25 Aug 2020 11:13:08 -0400 2020-11-24T19:00:00-05:00 2020-11-24T20:30:00-05:00 Lurie Biomedical Engineering The Bioethics Discussion Group Lecture / Discussion The Coming Administration
Bioethics Discussion: The Coming Administration (November 24, 2020 7:00pm) https://events.umich.edu/event/58832 58832-20382972@events.umich.edu Event Begins: Tuesday, November 24, 2020 7:00pm
Location: Off Campus Location
Organized By: The Bioethics Discussion Group

A discussion on our (new?) government.

A few readings to consider:
––Three Ways to Politicize Bioethics
––Affording Obamacare
––Confronting Deep Moral Disagreement: The President’s Council on Bioethics, Moral Status, and Human Embryos
––The role of party politics in medical malpractice tort reforms

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/051-the-coming-administration/.

Please also swing by the blog: https://belmont.bme.umich.edu/incidental-art/

––
[OUR FIRST PLANNED REMOTE DISCUSSION]
While people are still allowed on campus, discussions will be held on the front lawn of Lurie Biomedical Engineering building. Participants will be asked to enter the area via a “welcome desk” where there will be hand sanitizer, wipes, etc. Participants will be masked, at least 12 feet from one another, and speaking through megaphones with one another. In accordance with public health mandates and guidance, participation will be limited to 20 individuals who sign up to participate ahead of time.

Sign up here: https://belmont.bme.umich.edu/ask-your-questions-to-ponder/

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Lecture / Discussion Tue, 25 Aug 2020 11:13:08 -0400 2020-11-24T19:00:00-05:00 2020-11-24T20:30:00-05:00 Off Campus Location The Bioethics Discussion Group Lecture / Discussion The Coming Administration
An Industrial Engineering-Based Approach to Designing and Evaluating Healthcare Systems to Improve Veteran Access to Care (November 30, 2020 4:30pm) https://events.umich.edu/event/79527 79527-20351367@events.umich.edu Event Begins: Monday, November 30, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Access to healthcare is a critical public health issue in the United States, especially for veterans. Veterans are older on average than the general U.S. population and are thus at higher risk for chronic disease. Further, veterans report more delays when seeking healthcare. The Veterans Affairs (VA) Healthcare System continuously works to develop policies and technologies that aim to improve veteran access to care. Industrial engineering methods can be effective in analyzing the impact of such policies, as well as designing or modifying systems to better align veteran patients’ needs with providers and resources.

In the talk, I will focus on veteran access to chronic eye disease screening. Ophthalmologists in the VA have developed a platform in which ophthalmic technicians screen patients for major chronic eye diseases during primary care visits. We use mixed-integer programming-based facility location models to understand how the VA can determine which clinics should offer eye screenings, which provider type(s) should staff those clinics, and how to distribute patients among clinics. The results of this work show how the VA can achieve various objectives including minimizing the cost of treating a given population or maximizing the number of patients receiving care given a fixed budget.

Adam VanDeusen is a PhD candidate in Industrial and Operations Engineering at the University of Michigan working under Dr. Amy Cohn. His work applies operations research and systems engineering methods to public health policy and access to healthcare. As part of his graduate training, Adam works with the University of Michigan Center for Healthcare Engineering & Patient Safety (CHEPS). Adam completed his undergraduate degree in Industrial and Operations Engineering at the University of Michigan and his Master of Public Health in Chronic Disease Epidemiology from Yale School of Public Health. Prior to beginning his PhD, Adam worked as the Senior Director of Clinical Programs at the Health Management Academy and as a Health Systems Engineer at Mayo Clinic.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Fri, 20 Nov 2020 15:23:50 -0500 2020-11-30T16:30:00-05:00 2020-11-30T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Adam VanDeusen
Science Success Series | Medical School Inside Story (November 30, 2020 5:00pm) https://events.umich.edu/event/76332 76332-19687524@events.umich.edu Event Begins: Monday, November 30, 2020 5:00pm
Location: Off Campus Location
Organized By: Science Learning Center

Do you have questions about medical school admissions? Get your answers straight from the inside! U-M Medical School Admissions Director Carol Teener will demystify medical school applications, expectations, and reviews in her presentation.

Register on Sessions: https://sessions.studentlife.umich.edu/track/event/session/29208

Email ScienceSuccessSeries@umich.edu with any questions.

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Workshop / Seminar Fri, 28 Aug 2020 17:14:02 -0400 2020-11-30T17:00:00-05:00 2020-11-30T18:00:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar
CSCS Seminar | Developing a systematic approach to modulate the emergence of consciousness from pharmacologically-and pathologically induced unconsciousness (December 1, 2020 11:30am) https://events.umich.edu/event/76220 76220-19677552@events.umich.edu Event Begins: Tuesday, December 1, 2020 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

ZOOM MEETING LINK: myumi.ch/v2ZYv

Re-scheduled from earlier this fall.

ABSTRACT:
Why is it so difficult to develop a systematic approach to modulate the recovery of consciousness from pharmacologically and pathologically induced unconsciousness? Three things are required to develop a systematic approach; a reliable neural activity that corresponds to consciousness, a reliable brain stimulation to induce the target neural activity, and a mechanism to guarantee the induced neural activity results in consciousness. However, no single neural activity or a mechanism has been identified yet as a neural correlate of consciousness, suggesting that consciousness might emerge through complex interactions of spatially and temporally distributed brain functions. Accumulating evidence from computational model and empirical studies suggest that brain criticality – a balanced state between order and disorder, stability and instability, incoherent and synchronized connectivity at a global network level, is a necessary condition for the emergence of consciousness. Thus, in our research project, we hypothesized that with modulating brain network criticality, we may be able to control the state transition during the loss and recovery of consciousness in general anesthesia and coma. In this talk, I will introduce our current project that aims to develop a systematic method to precisely evaluate a brain state in altered states of consciousness and to control the emergence from unconsciousness, which is based on highly advanced methods in physics, network science, and neurobiology of consciousness.

Please join us 15 minutes before and after the seminar for a social coffee hangout. Put your speakers and video on and say hi to old friends or go to the 'lounge' and chat with an acquaintance

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Livestream / Virtual Mon, 23 Nov 2020 16:33:23 -0500 2020-12-01T11:30:00-05:00 2020-12-01T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Photo of UnCheol Lee
BME Master's Defense: George Malinee (December 2, 2020 6:30am) https://events.umich.edu/event/79643 79643-20438361@events.umich.edu Event Begins: Wednesday, December 2, 2020 6:30am
Location: Off Campus Location
Organized By: Biomedical Engineering

Traumatic bone injuries are very common orthopedic conditions that often require advanced treatment. The Masquelet technique is an existing two-stage surgical method used to heal traumatic injuries and non-unions. Last year in the United States alone there were 500,000 bone graft procedures performed to heal and treat these traumatic bone injuries or defects. The majority of these grafting procedures are necessary due to the size of these defects. These defects are called critical size defects and are defined by defects that are too large to heal naturally or defects that are more than 2.5 times the radius of the bone. The crux of the Masqulet technique is the induction of a biological membrane that provides the proper environment for osteogenesis. There is a desire to use a tissue engineering approach to fabricate and culture these membranes in vitro to later be used as part of the Masquelet technique. A tissue engineering approach was taken to engineer these membranes using a fibrin hydrogel platform seeded with normal human lung fibroblasts or a co-culture of fibroblasts or human umbilical vein endothelial cells. Constructs were analyzed for axial and radial compaction, cell viability, and cell morphology at differing time points and under different culture media conditions. Viable, vascularized constructs were able to be reliably manufactured and cultured allowing for characterization of the system. Although this work is not exhaustive, it sheds some light on a possible tissue engineering approach to work in conjunction with the Masquelet technique. Future work will focus on exploring other properties of the fibrin constructs as well as characterizing constructs made of collagen, and a combination of collagen and fibrin.

Date: Wednesday, December 2, 2020
Time: 6:30 AM
Zoom: https://umich.zoom.us/j/92706362206
Chair: Dr. Jan Stegemann

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Lecture / Discussion Tue, 01 Dec 2020 13:54:12 -0500 2020-12-02T06:30:00-05:00 2020-12-02T07:30:00-05:00 Off Campus Location Biomedical Engineering Lecture / Discussion U-M BME Event
DCMB / CCMB Weekly Seminar (December 2, 2020 4:00pm) https://events.umich.edu/event/79631 79631-20436379@events.umich.edu Event Begins: Wednesday, December 2, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

ABSTRACT: The brain is made of networks of neurons that send information to each other via spikes. Sleep and wake are the most clearly definable brain states and each exerts unique effects upon neural network spiking activity. We used large-scale recordings in the frontal cortex of mice and rats to examine the activity of neurons during wake/sleep cycles and found that a novel form of homeostatic action is taken by sleep: homogenization of firing rates. Whereas it was previously believed that sleep simple decreased firing rates, we found that this was much more true of the most active neurons only, thereby reducing the variance of the population.

To extend this observation of homeostatic forced during sleep we also examine how sleep and wake states interact with learning and performance, which is also facilitated by sleep. We have therefore begun to record before, during and after learning sessions to determine how learning interacts with the usual homeostatic effects of sleep. Further we can also record how waking changes in brain states such as motivation and attention modulate firing and information processing by neurons during behavior itself.

Finally, our end-goal to translate these kinds of basic neurobiologic observations in healthy rodents to states of stress or treatments of stress. Unfortunately the chronic stress states of relevance to psychiatric disease do not last seconds but days and weeks. We have therefore begun to build new long-term recording environments to enable future experiments over these time-spans.

BIOGRAPHY:
Dr. Watson is an assistant professor in psychiatry at the University of Michigan. He grew up in Ann Arbor and then obtained his BA from Cornell University and his M.D. and Ph.D. degrees from Columbia University. During his Ph.D. he used two-photon microscopy to study the behavior of neurons in local cortical microcircuits. During his doctoral work he also participated in technical development of multi-beam two photon imaging techniques. Upon graduation from medical school, Dr. Watson pursued a residency in Psychiatry at Weill Cornell Medical College as well postdoctoral work at New York University. He received the National Institute for Mental Health’s Outstanding Resident Award, the American Psychiatric Association’s Lilly Research Fellowship and the Leon Levy Neuroscience Fellowship. He did a fellowship with Dr. Gyorgy Buzsaki at NYU to record ongoing activity in naturally behaving and sleeping animals wherein he showed that sleep reorganizes neuronal firing architecture in the neocortex in previously unknown ways. He is now combining his electrical recordings with behavioral tools to deepen his understanding of both use and regulation of cortical brain circuits.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 01 Dec 2020 09:45:44 -0500 2020-12-02T16:00:00-05:00 2020-12-02T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Honors Grand Rounds with Leana May, DO MPH (December 2, 2020 7:00pm) https://events.umich.edu/event/76328 76328-19687521@events.umich.edu Event Begins: Wednesday, December 2, 2020 7:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

Join Stephanie Chervin, Honors premed advisor, for a virtual live discussion with Honors alum Leana May DO, MPH; Assistant Professor of Pediatrics, University of Colorado. This program is for current LSA Honors Program students only. A link to the virtual event will be sent to all registrants before the event.

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Presentation Fri, 28 Aug 2020 15:57:49 -0400 2020-12-02T19:00:00-05:00 2020-12-02T20:00:00-05:00 Off Campus Location LSA Honors Program Presentation Dr. May
“Mesenchymal Regulation of Tooth Root Formation and Eruption” (December 3, 2020 12:00pm) https://events.umich.edu/event/79611 79611-20430435@events.umich.edu Event Begins: Thursday, December 3, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Wanida Ono, PhD
Assistant Professor, Orthodontics and Pediatric Dentistry
University of Michigan School of Dentistry

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Workshop / Seminar Mon, 30 Nov 2020 14:32:33 -0500 2020-12-03T12:00:00-05:00 2020-12-03T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Workshop / Seminar Ono
Forecasting and Stochastic Programming Models to Address Uncertainty in the Trauma System Configuration Problem (December 7, 2020 4:30pm) https://events.umich.edu/event/79689 79689-20454252@events.umich.edu Event Begins: Monday, December 7, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Trauma care services are a vital part of all healthcare-based network as timely accessibility is important for citizens. Trauma care access is even more relevant when unexpected events such as the COVID-19 pandemic overload the capacity of the hospitals. Research literature has highlighted that access to trauma care is not even for all populations, especially when comparing rural and urban groups. Historically, the configuration of a trauma system was often not considered as a whole but instead hinged on the designation and verification of individual hospitals as trauma care centers. Recognition of the benefits of an inclusive trauma system has precipitated a more holistic approach. The optimal geographic configuration of trauma care centers is key to maximizing accessibility while promoting the efficient use of resources. This talk focuses on analyzing and forecasting physical trauma sustained from accidents, in environments both personal and work related, pertaining to individual injuries and to formulate a stochastic programming model that utilizes recorded injuries as demands to place trauma centers in the most optimal location. The first part of the talk discusses the limitations faced by the existing trauma healthcare infrastructure by forecasting the expected number of people requiring the services of trauma facilities for both rural and urban locations in Texas. Five types of forecasting methods were analyzed to determine the best option to utilize for forecasting for individual data sets. The aim is to identify which forecasting model performs the best for given data sets that can be used to forecast patient demand for a given location and determine the optimal locations for trauma network expansion. The second part of the talk reports on the development of a two-stage stochastic optimization model for geospatial expansion of a trauma network in the state of Texas. The stochastic optimization model recommends the siting of new trauma care centers according to the geographic distribution of the injured population. The model has the potential to benefit both patients and institutions, by facilitating prompt access and promoting the efficient use of resources.

Eduardo Pérez is an Associate Professor in the Ingram School of Engineering at Texas State University. He was a Postdoctoral Research Associate in the Department of Industrial and Systems Engineering at Texas A&M University from 2010 to 2012. He received his PhD in Industrial and Systems Engineering from Texas A&M University in 2010 and his B.S. in Industrial Engineering from the University of Puerto Rico at Mayagüez, Puerto Rico in 2004. Dr. Pérez’s research interests are in the use of methodologies and theories in operations research, systems engineering, discrete-event simulation, algorithms and software design, and decision theory analysis to solve problems in service systems. Some of his research project sponsors include the National Science Foundation (NSF), the Department of Homeland Security (DHS), the Robert Wood Johnson Foundation, Baylor Scott & White Health System, Adventist Health System, and the NEC Corporation. Dr. Eduardo Pérez is a member of the Institute of Industrial Engineers (IIE), the Institute for Operations Research and Management Sciences (INFORMS), and the Society for Computer Simulation International (SCS). He received his Engineering-In-Training (EIT) certification in 2004. He is the director of the Integrated Modeling and Optimization for Service Systems (iMOSS) research laboratory.

For a full listing of our Fall 2020 seminars, see https://cheps.engin.umich.edu/seminar-series/2020-seminar/

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.
For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP.
For additional questions, contact CHEPSseminar@umich.edu.
Photographs, screen captures, and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 03 Dec 2020 15:50:46 -0500 2020-12-07T16:30:00-05:00 2020-12-07T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Eduardo Pérez, Ph.D.
Department of Computational Medicine & Bioinformatics Weekly Wednesday Seminar (December 9, 2020 4:00pm) https://events.umich.edu/event/79756 79756-20484062@events.umich.edu Event Begins: Wednesday, December 9, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Learning objectives:

1. Discuss the conceptual distinction and clinical utility of self-reported race/ethnicity and genetic ancestry in childhood asthma.
2. Discuss the role of genetic ancestry and socio-environmental exposures in childhood asthma.
3. Discuss ancestry-specific polygenic risk scores, precision medicine and childhood asthma disparities.

Short bio: Dr. Mersha is currently an Associate Professor in the Division of Asthma Research and leads the Population Genetics, Ancestry, and Bioinformatics (pGAB) Laboratory (https://research.cchmc.org/mershalab/Home.php).
Dr. Mersha’s research combines quantitative, ancestry and statistical genomics to unravel genetic and non-genetic contributions to complex diseases and racial disparities in human populations, particularly asthma and asthma-related allergic disorders. Much of his research is at the interface of genetic ancestry, statistics, bioinformatics, and functional genomics, and he is interested in cross-line disciplines to unravel the interplay between genome and envirome underlying asthma risk. His long-term research goal is to understand and dissect how biologic predisposition and environmental exposures interact to shape racial disparities in complex disorders.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 07 Dec 2020 11:27:42 -0500 2020-12-09T16:00:00-05:00 2020-12-09T17:15:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Tesfaye ("Tes") Mersha, PhD (Associate Professor, Division of Asthma Research at Cincinnati Children's Hospital Medical Center)
Ethics and Equity in the State and Michigan Medicine during the COVID Pandemic (December 9, 2020 4:00pm) https://events.umich.edu/event/79400 79400-20296433@events.umich.edu Event Begins: Wednesday, December 9, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

This discussion will include managing COVID-19 at Michigan Medicine and at the State policy level. Participants will develop a greater understanding of, and will be able to routinely consider, ethical and policy issues to maximize positive outcomes for patients with COVID-19 or at risk of getting COVID-19.

featuring:

Joneigh S. Khaldun, M.D., MPH, FACEP, Chief Medical Executive and Chief Deputy Director for Health and Human Services; Michigan Department of Health and Human Services

Susan Dorr Goold, M.D., MHSA, MA, FACP, Professor of Internal Medicine and Health Management Policy, University of Michigan

Andrew Shuman, M.D., FACS, Co-Chief, Clinical Ethics Service Center for Bioethics and Social Sciences in Medicine, University of Michigan

panel moderator:

Sandro Cinti, M.D., Professor of Infectious Diseases, Internal Medicine, University of Michigan & Ann Arbor VA

The University of Michigan Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Michigan Medical School designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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Lecture / Discussion Wed, 02 Dec 2020 10:50:26 -0500 2020-12-09T16:00:00-05:00 2020-12-09T17:30:00-05:00 Off Campus Location Michigan Medicine Lecture / Discussion Waggoner Lecture speakers
Clinical Simulation Center Brown Bag Series (December 11, 2020 12:00pm) https://events.umich.edu/event/79224 79224-20231466@events.umich.edu Event Begins: Friday, December 11, 2020 12:00pm
Location: Off Campus Location
Organized By: Clinical Simulation Center

Dr. Munzer is a Clinical Lecturer, in the Department of Emergency Medicine at Michigan Medicine. He joined the University’s Medical Education Fellowship after completing his training in Emergency Medicine with the University of Michigan/St. Joseph Mercy Hospital Residency Program.

He will give an update on the Extracorporeal Membrane Oxygenation (ECMO) training and simulation program, including the new simulator in the Clinical Simulation Center, as well the goals of the program.

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Lecture / Discussion Thu, 05 Nov 2020 11:34:01 -0500 2020-12-11T12:00:00-05:00 2020-12-11T13:00:00-05:00 Off Campus Location Clinical Simulation Center Lecture / Discussion Extracorporeal Membrane Oxygenation (ECMO)
COVID-19 Vaccines: What We Know So Far (December 11, 2020 3:00pm) https://events.umich.edu/event/79853 79853-20509611@events.umich.edu Event Begins: Friday, December 11, 2020 3:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

News about COVID-19 vaccines is breaking daily. With the FDA meeting this week to discuss the Pfizer-BioNTech vaccine and more news sure to come quickly on its heels, emerging and infectious diseases specialist Dr. Sandro Cinti joins us for a livestream this Friday at 3pm to answer your questions about efficacy, safety and what we know so far about COVID-19 vaccines on the horizon.

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Livestream / Virtual Thu, 10 Dec 2020 12:09:13 -0500 2020-12-11T15:00:00-05:00 2020-12-11T16:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual COVID-19 Vaccine Livestream with Dr. Sandro Cinti
Season of Giving: Food Drive for Food Gatherers (December 14, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509614@events.umich.edu Event Begins: Monday, December 14, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-14T08:00:00-05:00 2020-12-14T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 15, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509615@events.umich.edu Event Begins: Tuesday, December 15, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-15T08:00:00-05:00 2020-12-15T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 16, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509616@events.umich.edu Event Begins: Wednesday, December 16, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-16T08:00:00-05:00 2020-12-16T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 17, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509617@events.umich.edu Event Begins: Thursday, December 17, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-17T08:00:00-05:00 2020-12-17T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 18, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509618@events.umich.edu Event Begins: Friday, December 18, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-18T08:00:00-05:00 2020-12-18T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 19, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509619@events.umich.edu Event Begins: Saturday, December 19, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-19T08:00:00-05:00 2020-12-19T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 20, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509620@events.umich.edu Event Begins: Sunday, December 20, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-20T08:00:00-05:00 2020-12-20T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 21, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509621@events.umich.edu Event Begins: Monday, December 21, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-21T08:00:00-05:00 2020-12-21T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Season of Giving: Food Drive for Food Gatherers (December 22, 2020 8:00am) https://events.umich.edu/event/79856 79856-20509622@events.umich.edu Event Begins: Tuesday, December 22, 2020 8:00am
Location: North Campus Research Complex Building 18
Organized By: Michigan Medicine

The season of giving has once again arrived in Michigan. But this one comes amid a surging pandemic, an economic downturn, and a looming deadline for continuation of federal financial relief.

All of these have created intense need in communities surrounding Michigan Medicine. In response, the University of Michigan’s academic medical center will launch a third effort to encourage its own team, and the local community, to give food and funds to support Food Gatherers.

Starting December 14, and continuing through the 22nd, this will include a convenient drive-up drop-off location for food and toiletries, open to U-M faculty, staff and students, and members of the community in a position to give. It's located at Dock 90 of the North Campus Research Complex, just off Huron Parkway.

Donors may give online via credit card, or get information about giving by mail or phone, at http://www.foodgatherers.org/UM.

Already this year, donors to Michigan Medicine’s previous two drives have contributed the equivalent of 128,000 meals for Food Gatherers to distribute to more than 170 agencies that serve people throughout Washtenaw County and beyond. Generous individuals have also given thousands of pounds of personal care items, from diapers to toothbrushes.

The donation drive started in March, as part of Michigan Medicine’s effort to gather much-needed personal protective equipment during the early days of the pandemic when normal supply chains were disrupted.

Since that time, Food Gatherers’ partners have experienced a consistent surge in demand from people affected by the economic effects of the pandemic. Uncertainty over the future of federal and state relief efforts is making planning difficult.

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Community Service Thu, 10 Dec 2020 12:17:50 -0500 2020-12-22T08:00:00-05:00 2020-12-22T17:00:00-05:00 North Campus Research Complex Building 18 Michigan Medicine Community Service Season of Giving Food Drive
Bioethics Discussion: The Madness of Crowds (January 12, 2021 7:00pm) https://events.umich.edu/event/58834 58834-14563726@events.umich.edu Event Begins: Tuesday, January 12, 2021 7:00pm
Location: Off Campus Location
Organized By: The Bioethics Discussion Group

A discussion on popular delusions.

Join us at: https://umich.zoom.us/j/99926126455.

A few readings from the madding crowd:
––The Liverpool Cholera Epidemic of 1 and Anatomical Dissection—Medical Mistrust and Civil Unrest
––The Wisdom of Crowds, the Madness of Crowds: Rethinking Peer Review in the Web Era
––The Hippocratic Thorn in Bioethics’ Hide: Cults, Sects, and Strangeness
––The Importance of Complying with Vaccination Protocols in Developed Countries: “Anti-Vax” Hysteria and the Spread of Severe Preventable Diseases

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/053-the-madness-of-crowds/.

––
It would be shear madness if you did not crowd the blog: https://belmont.bme.umich.edu/incidental-art/

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Lecture / Discussion Fri, 08 Jan 2021 09:42:27 -0500 2021-01-12T19:00:00-05:00 2021-01-12T20:30:00-05:00 Off Campus Location The Bioethics Discussion Group Lecture / Discussion The Madness of Crowds
MIDAS & Owkin Federated Learning in Biomedical Research Workshop (January 14, 2021 10:00am) https://events.umich.edu/event/80139 80139-20566722@events.umich.edu Event Begins: Thursday, January 14, 2021 10:00am
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Objective: Cultivating research collaboration, joint grants and connecting the UM researchers to the right organisations. Supports Owkin expansion of our presence in North America and facilitates collaborations with PIs at UM. A great introduction to what Owkin does to UM.

Introduction Owkin & Scientific Overview of the Sessions — Patrick Sin-Chan, Partnerships Manager – Owkin
Session 1: Methodology and Data Science
Learning From Others Without Sacrificing Privacy: Application of Federated Machine Learning to Mobile Health Data
Presenter: Ambuj Tewari, Associate Professor, Statistics
Privacy Preserving Federated Learning Platform: from Design to Deployment in Real World Use Cases
Presenter: Camille Marini
Accelerating Machine Learning with Multi-Armed Bandit
Barzan Mozafari, Associate Professor, Computer Science and Engineering
Siloed Federated Learning for Multi-Centric Histopathology Datasets
Presenter: Mathieu Andreux
20 mins Panel Discussion (MIDAS Moderator- Kayvan Najarian, Professor, Computational Medicine and Bioinformatics)
Session 2: Biotech/medical
Covid-19 Severity Analysis with CT Scans and Machine Learning
Presenter: Simon Jégou
Linking Single-cell Molecular States with Phenotypes Using Machine Learning
Presenter: Josh Welch, Assistant Professor, Computational Medicine and Bioinformatics
HE2RNA: a Deep Learning Model to Predict RNA-Seq Expression of Tumors from Whole Slide Images
Presenter: Alberto Romagnoni
Using Large-scale Pharmacogenomic Databases to Predict Drug Effectiveness
Presenter: Johann Gagnon-Bartsch, Assistant Professor, Statistics
20 mins Panel discussion (Owkin Moderator: Patrick Sin-Chan)

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Workshop / Seminar Thu, 17 Dec 2020 19:36:31 -0500 2021-01-14T10:00:00-05:00 2021-01-14T14:30:00-05:00 Off Campus Location Michigan Institute for Data Science Workshop / Seminar Okwin
2021 MaryFran Sowers Memorial Lecture "Discriminatory Stressors and Cardiovascular Risk in Midlife Women: Implications for African-American Women's Health" (January 14, 2021 12:00pm) https://events.umich.edu/event/80500 80500-20730280@events.umich.edu Event Begins: Thursday, January 14, 2021 12:00pm
Location: Off Campus Location
Organized By: Center for Midlife Science

This special lecture honors Dr. Sower’s extraordinary scientific contributions to the field of women’s health and to inspire young scholars to transcend the boundaries between varying fields of research to advance women’s health. Dr. Sower’s unique insights into the breadth and depth of underlying physiological processes common to multiple diseases as well as her efforts to understand the linkages between ovarian and chronological aging has contributed substantially to the advancement of science. As a result of her contributions, women’s health grew from a peripheral field of study to a major discipline and we honor her legacy by inviting a groundbreaking researcher to present a lecture in her name.

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Lecture / Discussion Thu, 07 Jan 2021 15:42:51 -0500 2021-01-14T12:00:00-05:00 2021-01-14T13:00:00-05:00 Off Campus Location Center for Midlife Science Lecture / Discussion Tene Lewis presents 2021 MaryFran Sowers Memorial Lecture
Artificial Intelligence & Machine Learning In Health Sciences Education (January 14, 2021 12:00pm) https://events.umich.edu/event/80071 80071-20554878@events.umich.edu Event Begins: Thursday, January 14, 2021 12:00pm
Location: Off Campus Location
Organized By: RISE (Research. Innovation. Scholarship. Education.)

Please join us on Thursday, January 14, 2021, 12:00 - 1:00 PM for a discussion on Artificial Intelligence & Machine Learning in Health Sciences Education. We are interested in learning more about how these new technologies can cultivate new approaches in teaching and learning that can improve health and science outcomes.

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Livestream / Virtual Wed, 16 Dec 2020 07:13:27 -0500 2021-01-14T12:00:00-05:00 2021-01-14T13:00:00-05:00 Off Campus Location RISE (Research. Innovation. Scholarship. Education.) Livestream / Virtual RISE Virtual Talking Circle
COVID-19 Vaccines: An Inside Look at the Development and Rollout (January 14, 2021 1:00pm) https://events.umich.edu/event/80393 80393-20713710@events.umich.edu Event Begins: Thursday, January 14, 2021 1:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

Our experts will discuss how the new COVID-19 vaccines were developed, how they are being rolled out, and the differences among the various vaccines.

Participants are invited to send questions for the Q&A ahead of time or during the webinar. Questions received prior to January 8 will be considered for the panel. Registered attendees will receive details about accessing the discussion the morning of the event.

Register to get the link, and submit questions in advance, via https://umich.formstack.com/forms/january_well_aware_rsvp?fbclid=IwAR0Y5yG9niS2Oy70mZZro0kAICOw-2tAhr6dqJoE9XXGnbcBBQVE-1FbQws

Speakers:
Sandro Cinti, M.D.
Professor of Internal Medicine

Stanley Kent, R.Ph.
Chief Pharmacy Officer, Michigan Medicine
Associate Dean for Clinical Affairs, College of Pharmacy

Anna Suk-Fong Lok, M.D.
Alice Lohrman Andrews Research Professor of Hepatology
Dame Sheila Sherlock Distinguished University Professor of Hepatology and Internal Medicine
Assistant Dean for Clinical Research

Njira Lucia Lugogo, M.D.
Associate Professor of Internal Medicine

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Livestream / Virtual Thu, 07 Jan 2021 17:40:59 -0500 2021-01-14T13:00:00-05:00 2021-01-14T14:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual Person getting vaccinated against COVID-19
Dehumanization During Covid-19: Resurrection of the Family as Part of the Patient’s Healing Plan (January 15, 2021 12:00pm) https://events.umich.edu/event/80119 80119-20564737@events.umich.edu Event Begins: Friday, January 15, 2021 12:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

E. Wesley Ely, MD, MPH, Professor of Medicine at Vanderbilt University School of Medicine

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Workshop / Seminar Thu, 17 Dec 2020 14:35:31 -0500 2021-01-15T12:00:00-05:00 2021-01-15T13:00:00-05:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar
COVID-19 and the African American Community (January 16, 2021 1:00pm) https://events.umich.edu/event/80498 80498-20730283@events.umich.edu Event Begins: Saturday, January 16, 2021 1:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

This virtual discussion about COVID-19, the vaccine, and health disparities will feature several local experts. Panelists will provide science-based facts to help you make an informed choice about your health.

The panel includes:
Keila Samuels, PharmD, a clinical pharmacist in the Division of Allergy and Immunology at Michigan Medicine
Jessie Kimbrough Marshall, M.D., MPH, an adjunct assistant professor in the Division of Hospital Medicine at Michigan Medicine
Bishop Harry S. Grayson, pastor of Messias Temple Church

The moderator is Othelia Pryor, Ph.D., senior project manager at the Office for Health Equity & Inclusion at Michigan Medicine

The panelists will share facts based on science, acknowledge the lack of trust of healthcare by African Americans, discuss steps toward equitable and ethical healthcare, and share their personal stories about COVID-19, vaccines and health disparities.
To receive the link to watch the event, and to submit a question for consideration, visit https://michmed.org/6dzbK
A phone option is also available.

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Livestream / Virtual Thu, 07 Jan 2021 15:48:52 -0500 2021-01-16T13:00:00-05:00 2021-01-16T14:30:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual Panelists for COVID-19 and the African-American Community
U-M Health Sciences 2021 MLK Keynote (January 18, 2021 12:00pm) https://events.umich.edu/event/79757 79757-20484063@events.umich.edu Event Begins: Monday, January 18, 2021 12:00pm
Location: Off Campus Location
Organized By: School of Kinesiology

Bodies represent the sites of socially constructed differences and power relations. As such, the personal is political, and bodies are subject to political interpretations. Body politics based on racial (and/or ethnic) ascriptions (along with other intersecting elements such as sex, gender, sexuality, age, social class, ability, etc.) have adversely affected the overall health and wellness of bodies of Color in general, and Black bodies in particular - impacting their abilities, opportunities, access (inclusion/exclusion), care/treatment, and the overall nature of their lived experiences. Consequently, racialed body politics have contributed to an array of health disparities being more pronounced in communities of Color. However, movement offers a variety of health benefits and is therefore, a source of empowerment for racially politicized bodies.

This event will feature a keynote presentation by Dr. Monique Butler, U-M Kinesiology alumna and Chief Medical Officer for HCA Healthcare North Florida Division. She will address the theme "Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment."

This event is sponsored by the U-M Health Sciences units and hosted by the School of Kinesiology.

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Lecture / Discussion Tue, 05 Jan 2021 16:27:06 -0500 2021-01-18T12:00:00-05:00 2021-01-18T13:30:00-05:00 Off Campus Location School of Kinesiology Lecture / Discussion U-M Health Sciences 2021 MLK Keynote - Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment - with Dr. Monique Butler, MD
Modeling basal cell carcinoma: stem cell origin, drug response and tumor dormancy (January 18, 2021 1:00pm) https://events.umich.edu/event/80883 80883-20816992@events.umich.edu Event Begins: Monday, January 18, 2021 1:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Associate Professor of Dermatology and Associate Professor of Cell and Development Biology, University of Michigan Medical School

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Workshop / Seminar Mon, 18 Jan 2021 13:44:33 -0500 2021-01-18T13:00:00-05:00 2021-01-18T14:00:00-05:00 Off Campus Location Office of Research School of Dentistry Workshop / Seminar Sunny Wong
KNOWLEDGE EXTRACTION TO ACCELERATE SCIENTIFIC DISCOVERY (January 18, 2021 4:00pm) https://events.umich.edu/event/79534 79534-20373071@events.umich.edu Event Begins: Monday, January 18, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

To combat COVID-19, clinicians and scientists all need to digest the vast amount of relevant biomedical knowledge in literature to understand the disease mechanism and the related biological functions. The first challenge is quantity. For example, nearly 2.7K new papers are published at PubMed per day. This knowledge bottleneck causes significant delay in the development of vaccines and drugs for COVID-19. The second challenge is quality due to the rise and rapid, extensive publications of preprint manuscripts without pre-publication peer review. Many research results about coronavirus from different research labs and sources are redundant, complementary or event conflicting with each other.

Let’s consider drug repurposing as a case study. Besides the long process of clinical trial and biomedical experiments, another major cause for the long process is the complexity of the problem involved and the difficulty in drug discovery in general. The current clinical trials for drug re-purposing mainly rely on symptoms by considering drugs that can treat diseases with similar symptoms. However, there are too many drug candidates and too much misinformation published from multiple sources. In addition to a ranked list of drugs, clinicians and scientists also aim to gain new insights into the underlying molecular cellular mechanisms on Covid-19, and which pre-existing conditions may affect the mortality and severity of this disease.

To tackle these two challenges, we have developed a novel and comprehensive knowledge discovery framework, COVID-KG, to accelerate scientific discovery and build a bridge between clinicians and biology scientists. COVID-KG starts by reading existing papers to build multimedia knowledge graphs (KGs), in which nodes are entities/concepts and edges represent relations involving these entities, extracted from both text and images. Given the KGs enriched with path ranking and evidence mining, COVID-KG answers natural language questions effectively. Using drug repurposing as a case study, for 11 typical questions that human experts aim to explore, we integrate our techniques to generate a comprehensive report for each candidate drug. Preliminary assessment by expert clinicians and medical school students show our generated reports are informative and sound. I will also talk about our ongoing work to extend this framework to other domains including molecular synthesis and agriculture.

Bio:

Heng Ji is a professor at Computer Science Department, and an affiliated faculty member at Electrical and Computer Engineering Department of University of Illinois at Urbana-Champaign. She is also an Amazon Scholar. She received her B.A. and M. A. in Computational Linguistics from Tsinghua University, and her M.S. and Ph.D. in Computer Science from New York University. Her research interests focus on Natural Language Processing, especially on Multimedia Multilingual Information Extraction, Knowledge Base Population and Knowledge-driven Generation. She was selected as “Young Scientist” and a member of the Global Future Council on the Future of Computing by the World Economic Forum in 2016 and 2017. The awards she received include “AI’s 10 to Watch” Award by IEEE Intelligent Systems in 2013, NSF CAREER award in 2009, Google Research Award in 2009 and 2014, IBM Watson Faculty Award in 2012 and 2014 and Bosch Research Award in 2014-2018, and ACL2020 Best Demo Paper Award. She was invited by the Secretary of the U.S. Air Force and AFRL to join Air Force Data Analytics Expert Panel to inform the Air Force Strategy 2030. She is the lead of many multi-institution projects and tasks, including the U.S. ARL projects on information fusion and knowledge networks construction, DARPA DEFT Tinker Bell team and DARPA KAIROS RESIN team. She has coordinated the NIST TAC Knowledge Base Population task since 2010. She has served as the Program Committee Co-Chair of many conferences including NAACL-HLT2018. She is elected as the North American Chapter of the Association for Computational Linguistics (NAACL) secretary 2020-2021. Her research has been widely supported by the U.S. government agencies (DARPA, ARL, IARPA, NSF, AFRL, DHS) and industry (Amazon, Google, Bosch, IBM, Disney).

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Performance Mon, 23 Nov 2020 09:48:55 -0500 2021-01-18T16:00:00-05:00 2021-01-18T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Performance Heng Li
Covid-19 Health Update: Trends, Treatment and Vaccines (January 19, 2021 10:00am) https://events.umich.edu/event/79997 79997-20541124@events.umich.edu Event Begins: Tuesday, January 19, 2021 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

UM Epidemiologist Emily Toth Martin and UM Infectious Disease Physician Lona Mody will explore the latest updates in Covid-19 on campus, in Ann Arbor and across the state; treatment successes and challenges; and vaccine outlook.

Dr. Emily Toth Martin, PhD, MPH, is on the faculty of Epidemiology at the UM School of Public Health. Her research focuses on building a greater understanding of the epidemiology of viral respiratory diseases (including RSV, bocavirus and influenza) through the use of molecular epidemiology. In particular, her work aims to identify strategies to reduce infections, particularly in individuals with chronic comorbidities and in hospital infectious environments (including MRSA/VRE coinfection).

Lona Mody, MD, is one of very few internists in this country with an expertise in aging populations, epidemiology, an active research laboratory in microbiology and a translational research agenda focused on vulnerable aging population. Her NIH and AHRQ funded work has created a thriving consortium of post-acute and long-term care facilities in SE Michigan interested in developing interventions to enhance infection prevention in a traditionally resource poor setting.

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Class / Instruction Fri, 15 Jan 2021 18:10:49 -0500 2021-01-19T10:00:00-05:00 2021-01-19T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Urgent and Critical Issues
LHS Collaboratory (January 21, 2021 11:30am) https://events.umich.edu/event/80293 80293-20688136@events.umich.edu Event Begins: Thursday, January 21, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

The LHS Collaboratory presents Rachel Richesson, PhD, MPH, MS, FACMI, Professor of Learning Health Sciences, Department of Learning Health Sciences at the University of Michigan in a virtual event on 1/21/2021 from 11:30 am to 1:00 pm ET.

Professor Richesson's talk, "Data Standards and Learning Health Systems –Challenges and Opportunities," will be followed by an audience Q&A. Questions are also encouraged prior to the event.

Please send questions to LHSCollaboratory-info@umich.edu.

Registration in advance at: https://umich-health.zoom.us/webinar/register/WN_HytRsYwITc6oOGRj0F_MOA

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Livestream / Virtual Sat, 02 Jan 2021 10:24:08 -0500 2021-01-21T11:30:00-05:00 2021-01-21T13:00:00-05:00 Off Campus Location Department of Learning Health Sciences Livestream / Virtual LHS Collaboratory logo
DCM&B Tools and Technology Seminar (January 21, 2021 12:00pm) https://events.umich.edu/event/79833 79833-20507641@events.umich.edu Event Begins: Thursday, January 21, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 07:58:47 -0500 2021-01-21T12:00:00-05:00 2021-01-21T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
COVID-19 vaccine administration in the US and China: Policy, practice and perceptions (January 22, 2021 7:00am) https://events.umich.edu/event/80479 80479-20728299@events.umich.edu Event Begins: Friday, January 22, 2021 7:00am
Location: Off Campus Location
Organized By: UMMS Global REACH

The public health response to the COVID-19 pandemic in the U.S. has differed considerably from the approaches taken in China. Now that vaccines are becoming available. The approaches each country is taking to vaccination policies also seem to differ. Please join us for a conversation among trusted partners at UM and in China on the approaches that are being planned in the respective countries.

UMMS Senior Associate Dean for Education and Global Initiatives Joseph C. Kolars will moderate the discussion, featuring Hai Fang, from Peking University Health Science Center, and Michigan Medicine' Sandro Cinti.

A Professor at the China Center for Health Development Studies, Dr. Fang, PhD, is a renowned health economist. His research areas include health economic evaluation, vaccine economics, and health policy.

A leading expert on HIV clinical research as well as emerging infectious diseases, Dr. Cinti, MD, is a co-chair of the a multidisciplinary task force responsible for devising and overseeing Michigan Medicine’s vaccination strategy.

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Livestream / Virtual Fri, 08 Jan 2021 08:50:33 -0500 2021-01-22T07:00:00-05:00 2021-01-22T08:00:00-05:00 Off Campus Location UMMS Global REACH Livestream / Virtual COVID-19 vaccine administration in the US and China
RNA Seminar featuring: Elena Conti, Max Planck Institute of Biochemistry (January 25, 2021 9:00am) https://events.umich.edu/event/75826 75826-19613920@events.umich.edu Event Begins: Monday, January 25, 2021 9:00am
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

KEYWORDS: molecular mechanisms, RNA, ribosome, biochemistry, cryo-EM, X-ray crystallography

ABSTRACT: All RNAs in eukaryotic cells are eventually degraded. The RNA exosome is a conserved macromolecular machine that degrades a vast number and variety of RNAs. Exosome-mediated RNA degradation leads to the complete elimination of nuclear and cytoplasmic transcripts in turnover and quality control pathways, and to the partial trimming of RNA precursors in nuclear processing pathways. How the exosome combines specificity and versatility to either eliminate or process RNAs has been a long-standing question.

ZOOM REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_IjnWw1UcRkW8zcDeuAM2tQ

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Lecture / Discussion Mon, 04 Jan 2021 10:08:44 -0500 2021-01-25T09:00:00-05:00 2021-01-25T10:00:00-05:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Elena Conti, Max Planck Institute of Biochemistry
Michigan Communities, Conversations and COVID (January 25, 2021 6:00pm) https://events.umich.edu/event/80764 80764-20785450@events.umich.edu Event Begins: Monday, January 25, 2021 6:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

This event, presented by the Michigan Institute for Clinical & Health Research and the Community Health Services division of Michigan Medicine, gives the community an opportunity to reflect on the pandemic and vaccines, and to get questions answered by experts.

It features:
E. Yvonne Lewis, B.S., B.B.A., the co-director of the Healthy Flint Research Coordinating Center, the director of outreach for the Genesee Health Plan, and the co-community principal investigator for the Flint Center for Health Equity Solutions

Sandro Cinti, M.D., infectious disease specialist, professor of internal medicine and co-chair of the COVID Vaccine and Therapeutics Task Force at Michigan Medicine


Register to receive the link to watch via Zoom: https://umich.zoom.us/webi
nar/register/WN_6QfjU6xySTyfV45N65Q53Q

Call in to listen:
(646) 876-9923, enter ID 965 3793 8149

Or tune in via a Facebook live feed: https://www.facebook.com/UMMICHR

Submit questions in advance: https://umich.qualtrics.com/jfe/form/SV_20uAmRUXffoSX7D
or email kwikwi@umich.edu

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Livestream / Virtual Thu, 14 Jan 2021 13:59:59 -0500 2021-01-25T18:00:00-05:00 2021-01-25T19:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual
COVID-19: Treatments and Long-Term Effects (January 26, 2021 12:00pm) https://events.umich.edu/event/80628 80628-20767647@events.umich.edu Event Begins: Tuesday, January 26, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

This Department of Internal Medicine webinar for the general public will feature U-M experts sharing their research on novel treatments and therapeutics for COVID-19, as well as information on the vaccines and the long-term health effects of COVID-19.

The event will be held on Zoom; participants should register in advance to receive the link to join, and to ask questions in advance. Questions should be received by Jan. 21 to be considered by the panelists.

Moderator:

John M. Carethers, M.D.
C. Richard Boland Distinguished University Professor of Internal Medicine and Human Genetics
John G. Searle Professor of Internal Medicine
Chair, Department of Internal Medicine

Panelists:

Robert Dickson, M.D.
Associate Professor of Internal Medicine
Associate Professor of Microbiology and Immunology

Adam Lauring, M.D., Ph.D.
Associate Professor of Internal Medicine
Associate Professor of Microbiology and Immunology

David Markovitz, M.D.
Professor of Internal Medicine

Lindsay Petty, M.D.
Assistant Professor of Internal Medicine

Hallie Prescott, M.D.
Associate Professor of Internal Medicine

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Livestream / Virtual Tue, 12 Jan 2021 16:20:50 -0500 2021-01-26T12:00:00-05:00 2021-01-26T13:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual Tipping the scale on COVID-19
COVID-19 Vaccine Update and Q&A (January 26, 2021 1:00pm) https://events.umich.edu/event/80879 80879-20816987@events.umich.edu Event Begins: Tuesday, January 26, 2021 1:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

This event, presented by the Ann Arbor-Ypsilanti Chamber of Commerce, features a panel of experts from Saint Joseph Mercy Health System, IHA, Michigan Medicine and Washtenaw County Health Department. They will provide information based on science and answer audience questions.

The panel include Dr. Anu Malani, MD, Medical Director for Infection Prevention and Control, St. Joe's, Dr. Sandro Cinti, MD, Professor of Infectious Disease, Michigan Medicine, and Dr. Juan Marquez, Medical Director, Washtenaw County Health Department.

Register at https://zoom.us/webinar/register/WN_Y8qjkJARTZiP-s9-Tge2kQ

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Livestream / Virtual Mon, 18 Jan 2021 12:44:44 -0500 2021-01-26T13:00:00-05:00 2021-01-26T14:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual COVID vaccine and computer
Bioethics Discussion: Population Control (January 26, 2021 7:00pm) https://events.umich.edu/event/58835 58835-14563727@events.umich.edu Event Begins: Tuesday, January 26, 2021 7:00pm
Location: Lurie Biomedical Engineering
Organized By: The Bioethics Discussion Group

A discussion on limiting ourselves.

Join us at: https://umich.zoom.us/j/99926126455.

A few readings to consider:
––Population Control Policies and Fertility Convergence
––Contraception and its ethical considerations
––Must Growth Doom the Planet?
––The Population Control Holocaust

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/054-population-control/.

––
The masses will not be controlled at the blog: https://belmont.bme.umich.edu/incidental-art/

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Lecture / Discussion Fri, 08 Jan 2021 09:42:14 -0500 2021-01-26T19:00:00-05:00 2021-01-26T20:30:00-05:00 Lurie Biomedical Engineering The Bioethics Discussion Group Lecture / Discussion Population Control
Community Engaged Research: Reflections on MLK’s Legacy (January 27, 2021 2:00pm) https://events.umich.edu/event/79928 79928-20515560@events.umich.edu Event Begins: Wednesday, January 27, 2021 2:00pm
Location: Off Campus Location
Organized By: Institute for Social Research

ISR Presents:

Community Engaged Research: Reflections on MLK’s Legacy
January 27, 2021
2-3pm EST
https://umich.zoom.us/j/91449183213

Breanca Merritt is a Diversity Scholar at the University of Michigan and founding director of the Center for Research on Inclusion and Social Policy (CRISP) and clinical assistant professor in the O’Neill School of Public and Environmental Affairs at Indiana University-Purdue University Indianapolis. In this role, she and her team produce and disseminate research to lay audiences about complex social issues and inequitable outcomes through policy briefs and multidisciplinary research experiences for students with community organizations. Dr. Merritt’s work aims to inform both local stakeholders and academic audiences. Her applied, community-engaged research analyzes local trends and evaluates programs related to social service provision, equitable access and experiences, and systemic sources of poverty. Her academic work assesses how legislation and organizational practices contribute to disparate outcomes, especially for racial/ethnic minorities. Topics addressed by these projects include housing and homelessness, family financial stability, and criminal justice, among others. https://www.in.gov/fssa/thehub/4602.htm

Event Contact Info
Anna Massey
7347639989
abeattie@umich.edu
http://isr.umich.edu

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Livestream / Virtual Fri, 15 Jan 2021 13:56:17 -0500 2021-01-27T14:00:00-05:00 2021-01-27T15:00:00-05:00 Off Campus Location Institute for Social Research Livestream / Virtual event flyer
Department of Computational Medicine & Bioinformatics Seminar (January 27, 2021 4:00pm) https://events.umich.edu/event/80722 80722-20777538@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Massively parallel single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened the way to systematic tissue atlases in health and disease, but as the scale of data generation is growing, so is the need for computational pipelines for scaled analysis. We developed Cumulus, the first comprehensive cloud-based framework, to address the big data challenge arising from sc/snRNA-seq analysis. Cumulus combines the power of cloud computing with improvements in algorithm and implementation to achieve high scalability, low cost, user-friendliness and integrated support for a comprehensive set of features. We benchmark Cumulus on the Human Cell Atlas Census of Immune Cells dataset of bone marrow cells and show that it substantially improves efficiency over conventional frameworks, while maintaining or improving the quality of results, enabling large-scale studies.

In recent years, biologists have found that sc/snRNA-seq alone is not enough to reveal the full picture of how cells function and coordinate with each other in a complex tissue. They begin to couple sc/snRNA-seq with other common data modalities, such as single-cell ATAC-seq (scATAC-seq), single-cell Immune Repertoire sequencing (scIR-seq), spatial transcriptomics and mass cytometry. This data coupling is called single-cell multimodal omics. As it is becoming a new common practice, new analysis needs emerge along with two major computational challenges: big data challenge and integration challenge. The big data challenge requires us to develop scalable computational infrastructure and algorithms to deal with the ever-growing large datasets produced from the community. The integration challenge requires us to design new algorithms to enable holistic integration of heterogeneous data from different modalities. In the last part of my talk, I will discuss my team’s efforts and plans to develop Cumulus as an integrated data analysis framework for scaled single-cell multimodal omics.

Single-cell multimodal omics has the potential to provide a more comprehensive characterization of complex multicellular systems than the sum of its parts. As the datasets produced from the community keep growing substantially, the enhanced Cumulus will continue playing an important role in the effort to build atlases of complex tissues and organs at higher cellular resolution, and in leveraging them to understand the human body in health and disease.

Short bio: Dr. Bo Li is an assistant professor of medicine at Harvard Medical School, the director of Bioinformatics and Computational Biology at Center for Immunology Inflammatory Diseases, Massachusetts General Hospital, and an associate member of the Broad Institute of MIT and Harvard. His research focuses on large-scale single-cell and single-nucleus genomics data analysis. He received his Ph.D. in computer science from UW-Madison and completed two postdoctoral trainings with Dr. Lior Pachter at UC Berkeley and Dr. Aviv Regev at Broad Institute. He is best known for developing RSEM, an impactful RNA-seq transcript quantification software. RSEM is cited 9,384 times (Google Scholar) and adopted by several big consortia such as TCGA, ENCODE, GTEx and TOPMed.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 13 Jan 2021 14:32:34 -0500 2021-01-27T16:00:00-05:00 2021-01-27T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Bo Li, PhD (Assistant Professor at Harvard Medical School in Boston, MA)
Back to In-Person School During COVID-19: Live Q & A (January 28, 2021 12:00pm) https://events.umich.edu/event/81169 81169-20870026@events.umich.edu Event Begins: Thursday, January 28, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Medicine

Some students are beginning to return to face-to-face school after months of remote learning during the pandemic.

For many parents, there are still big questions about safety, including protecting their families from exposure to the virus and how children and schools may contribute to COVID-19 transmission in communities.

Families may also face behavioral, social and emotional challenges as children and teens readjust (again) to a new normal in their learning environments.

Experts from U-M's C.S. Mott Children's Hospital will answer some of families’ top questions about returning to in-person learning.

Topics to be addressed include:
• What research says about transmission and COVID-19 health risks in kids
• Contact with at-risk family members like grandparents
• How to know if your child should stay home from school
• Making decisions about continuing remote learning
• Helping kids adjust to the new school normal
• Supporting kids’ emotional, social and mental health
• Managing behavioral challenges during the transition
• Advice for families of children with special learning needs
• Re-engaging children who may have been disengaged during remote learning
• How to respond (and how not to respond) to disappointed teens who continue to miss milestones
And more

Viewers may ask questions live at the time of the event or add them to the event discussion area here to be considered.

The discussion will be moderated by developmental behavioral pediatrician Jenny Radesky, M.D., and the panel will also include pediatric infectious disease specialist Alison Tribble, M.D., and Terry Bravender, M.D., chief of adolescent medicine at Mott.

Broadcast live on @mottchildren Facebook and Twitter channels as well as Michigan Medicine's YouTube channel

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Livestream / Virtual Mon, 25 Jan 2021 10:25:01 -0500 2021-01-28T12:00:00-05:00 2021-01-28T13:00:00-05:00 Off Campus Location Michigan Medicine Livestream / Virtual Mott livestream about return to in-person learning
DCM&B Tools and Technology Seminar (January 28, 2021 12:00pm) https://events.umich.edu/event/79924 79924-20515557@events.umich.edu Event Begins: Thursday, January 28, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Contact-map of a protein sequence dictates the global topology of structural fold. Accurate prediction of the contact-map is thus essential to protein 3D structure prediction, which is particularly useful for the protein sequences that do not have close homology templates in the Protein Data Bank.

In this talk, we present a new method, ResPRE, to predict residue-level protein contacts using inverse covariance matrix (or precision matrix) of multiple sequence alignments (MSAs) through deep residual convolutional neural network training. Detailed data analyses show that the major advantage of ResPRE lies at the utilization of precision matrix that helps rule out transitional noises of contact-maps compared with the previously used covariance matrix. Meanwhile, the residual network with parallel shortcut layer connections increases the learning ability of deep neural network training. It was also found that appropriate collection of MSAs can further improve the accuracy of final contact-map predictions.

Tool Link: https://zhanglab.ccmb.med.umich.edu/ResPRE

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:30:40 -0500 2021-01-28T12:00:00-05:00 2021-01-28T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
Abstracts Due for 2021 Health Professions Education Day (February 2, 2021 1:00am) https://events.umich.edu/event/80496 80496-20730277@events.umich.edu Event Begins: Tuesday, February 2, 2021 1:00am
Location: Off Campus Location
Organized By: Center for Interprofessional Education

Join in the annual #UMHPEDAY, a virtual event to inspire future & current health professionals across @UMich to research, network & collaborate. Faculty, students, researchers and practitioners can submit poster abstracts by Feb. 2.

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Conference / Symposium Thu, 07 Jan 2021 15:09:19 -0500 2021-02-02T01:00:00-05:00 2021-02-02T23:00:00-05:00 Off Campus Location Center for Interprofessional Education Conference / Symposium Submit HPE Day abstracts by Feb. 2
History of Clinical Ethics and Ethics / Epidemics; and Clinical Ethics in the Time of Crisis (February 3, 2021 10:00am) https://events.umich.edu/event/79830 79830-20507637@events.umich.edu Event Begins: Wednesday, February 3, 2021 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

This event is part one of the three part "Medical Ethics 101" lecture series.

Our speaker is Christian Vercler, M.D., a practicing physician and faculty member of the University of Michigan Medical School.

Preregistration is required via the OLLI website or phone. A link to access the presentation will be e-mailed to you approximately one week prior to the event.

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Class / Instruction Thu, 10 Dec 2020 08:31:52 -0500 2021-02-03T10:00:00-05:00 2021-02-03T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Special Event
CCMB / DCMB Weekly Seminar Series (February 3, 2021 4:00pm) https://events.umich.edu/event/81571 81571-20927558@events.umich.edu Event Begins: Wednesday, February 3, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
Understanding intra-tumour heterogeneity (ITH), in particular identifying the presence of subclonal populations of cancer cells that may respond differently to treatments, is key to support precision medicine approaches. Capturing ITH from genomic measures raises however a number of computational challenges. In this talk I will present CloneSig, a method to infer ITH from "bulk" genomic data, in particular whole-exome sequencing data, and capture changes in mutational processes active in different subclones. I will then discuss the promises of single-cell genomics and some challenges it raises, in particular to transform raw count data into useful representations, integrate heterogeneous modalities, and learn gene regulation.

Short bio: Jean-Philippe Vert has been a research scientist at Google Brain in Paris and adjunct researcher at PSL University Mines ParisTech since 2018. He graduated from Ecole Polytechnique and holds a PhD in mathematics from Paris University. He was research professor and the founding director of the Centre for Computational Biology at Mines ParisTech from 2006 to 2018, team leader at the Curie Institute on computational biology of cancer (2008-2018), visiting scholar at UC Berkeley (2015-2016), and professor at the department of mathematics of Ecole normale supérieure in Paris (2016-2018).
His research interest concerns the development of statistical and machine learning methods, particularly to model complex, high-dimensional and structured data, with an application focus on computational biology, genomics and precision medicine. His recent contributions include new methods to embed structured data such as strings, graphs or permutations to vector spaces, regularization techniques to learn from limited amounts of data, and computationally efficient techniques for pattern detection and feature selection.
He is also working on several medical applications in cancer research, including quantifying and modeling cancer heterogeneity, predicting response to therapy, and modeling the genome and epigenome of cancer cells at the single-cell level.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 01 Feb 2021 14:12:04 -0500 2021-02-03T16:00:00-05:00 2021-02-03T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Jean-Philippe Vert, PhD (Research Scientist at Google Brain in Paris, Adjunct Researcher at PSL University Mines ParisTech)
Strengthening Systems for Health Seminar (February 3, 2021 5:00pm) https://events.umich.edu/event/81005 81005-20832764@events.umich.edu Event Begins: Wednesday, February 3, 2021 5:00pm
Location: Off Campus Location
Organized By: Center for Global Health Equity

Please join us for the next seminar by U-M's Center for Global Health Equity, including the following panelists:

Kirstin Scott, Medicine
John Scott, Medicine
Jody Lori, Nursing
Christabel Sefa, Center for Global Health Equity
Joseph Kolars, Medicine

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Workshop / Seminar Wed, 20 Jan 2021 13:49:30 -0500 2021-02-03T17:00:00-05:00 2021-02-03T18:30:00-05:00 Off Campus Location Center for Global Health Equity Workshop / Seminar Event Flyer
DCM&B Tools and Technology Seminar (February 4, 2021 12:00pm) https://events.umich.edu/event/79914 79914-20515545@events.umich.edu Event Begins: Thursday, February 4, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:00:22 -0500 2021-02-04T12:00:00-05:00 2021-02-04T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
Oral Health Sciences Semianr (February 4, 2021 12:00pm) https://events.umich.edu/event/81685 81685-20943434@events.umich.edu Event Begins: Thursday, February 4, 2021 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

YUYING XIE, PhD
Assistant Professor,
Department of Computational Mathematics, Science and Engineering; Department of Statistics and Probability
Michigan State University

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Presentation Wed, 03 Feb 2021 12:08:29 -0500 2021-02-04T12:00:00-05:00 2021-02-04T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Presentation Yuying Xie
BME 500 Seminar: Maria Coronel (February 4, 2021 4:00pm) https://events.umich.edu/event/81382 81382-20889813@events.umich.edu Event Begins: Thursday, February 4, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

BME Faculty Candidate
Maria Coronel, Ph.D.
Georgia Institute of Technology

Seminar Abstract:
Two major challenges to the translation of cellular-based tissue-engineered therapies are the lack of adequate oxygen support post-implantation and the need for systemic immunosuppression to halt the strong inflammatory and immunological response of the host. As such, strategies that aim at addressing oxygen demand, and local immunological responses can be highly beneficial in the translation of these therapies. In this seminar, I will focus on two biomaterial strategies to create a more favorable transplant niche for pancreatic islet transplantation. The first half will describe an in-situ oxygen-releasing biomaterial fabricated through the incorporation of solid peroxides in a silicone polymer. The implementation of this localized, controlled and sustained oxygen-generator mitigates the activation of detrimental hypoxia-induced pathways in islets and enhances the potency of extrahepatic 3D islet- loaded devices in a diabetic animal model. In the second part, I will focus on engineering synthetic biomaterials for the delivery of immunomodulatory signals for transplant acceptance. Biomaterial carriers fabricated with polyethylene glycol microgels are used to deliver immunomodulatory signals to regulate the local microenvironment and prevent allograft rejection in a clinically relevant pre-clinical transplant model. The use of synthetic materials as an off-the-shelf platform, without the need for manipulating the biological cell product, improves the clinical translatability of this engineered approach. Designing safer, responsive biomaterials to boost the delivery of targeted therapeutics will significantly reinvigorate interventional cell-based tissue-engineered therapies.

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Lecture / Discussion Fri, 29 Jan 2021 17:14:27 -0500 2021-02-04T16:00:00-05:00 2021-02-04T17:00:00-05:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
The Role of Narrative in the Development of a Jewish End of Life Ethic (February 8, 2021 12:00pm) https://events.umich.edu/event/80912 80912-20822887@events.umich.edu Event Begins: Monday, February 8, 2021 12:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

The Woll Family Speaker Series on Health, Spirituality and Religion presents Alan Jotkowitz, MD, MHA

Dr. Jotkowitz is a Professor of Medicine and Director, Medical School for International Health at the Ben-Gurion University of the Negev. His main academic interest is in the field of medical ethics and has published more than a 100 peer reviewed papers in such prestigious journals as the American Journal of Medicine, The European Journal of Medicine, The Journal of Medical Ethics, The American Journal of Bioethics and others. He is a member of the World Mizrachi's Speakers' Bureau and serves as the Associate Editor of The European Journal of Internal Medicine.

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Workshop / Seminar Tue, 19 Jan 2021 06:08:44 -0500 2021-02-08T12:00:00-05:00 2021-02-08T13:00:00-05:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar
Ethics at the End of Life: Principles and Case Discussions / The Interplay between Medical Ethics and Evolving Medical Science (February 10, 2021 10:00am) https://events.umich.edu/event/79831 79831-20507638@events.umich.edu Event Begins: Wednesday, February 10, 2021 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

This event is part two of the three part "Medical Ethics 101" lecture series.

Our speaker is Adam Marks, M.D., a practicing physician and faculty member of the University of Michigan Medical School.

Preregistration is required via the OLLI website or phone. A link to access the presentation will be e-mailed to you approximately one week prior to the event.

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Class / Instruction Thu, 10 Dec 2020 08:25:00 -0500 2021-02-10T10:00:00-05:00 2021-02-10T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Special Event
CCMB / DCMB Weekly Seminar (February 10, 2021 4:00pm) https://events.umich.edu/event/81413 81413-20893777@events.umich.edu Event Begins: Wednesday, February 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The increasing omics data and advanced AI technology present a great opportunity for novel biomarker-driven cancer therapies. My talk will cover two parts. First, I will introduce DrBioRight, a natural language-oriented and AI-driven analytic platform for omic data analysis. This platform allows users to perform analysis directly through human languages and it improves the performance through adaptive learning. Armed with NLP and AI technologies, this analytic will maximize the utility of omics data and lead to a new paradigm for biomedical research. Second, I will discuss our recent work on enhancer RNAs. We show that the eRNAs provide explanatory power for cancer phenotypes beyond that provided by mRNA expression through resolving intratumoral heterogeneity with enhancer cell-type specificity. Our study provides a high-resolution map of eRNA loci through which enhancer activities can be quantified by RNA-seq, enabling a broad range of biomedical investigations.

Bio: Dr. Liang is a Barnhart Family Distinguished Professor in Targeted Therapies and the Deputy Chair of Department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center. He is also a professor in the Department of Systems Biology. He received his B.S. in chemistry from Peking University (China) in 2001 and Ph.D. in quantitative and computational biology from Princeton University (NJ, USA) in 2006. Dr. Liang then finished his postdoctoral training in evolutionary and computational genomics at the University of Chicago. He joined MD Anderson Cancer Center as Assistant Professor and started his own group in 2009.
At MD Anderson, Dr. Liang’s group focuses on bioinformatics tool development, integrated cancer genomic analysis, regulatory RNA regulation/modification, and cancer systems biology. His systematic studies on enhancer regulation, RNA editing, functional proteomics, sex effects, and driver mutations in cancer have generated profound impacts on the biomedical research community and attracted wide attention such as The Wall Street Journal and Newsweek. The bioinformatics tools his group developed (such as TCPA, TANRIC, FASMIC, DrBioRight) collectively have >110,000 active users worldwide. Since 2010, he has published >140 papers total citation >25,000 times), including 41 corresponding-author papers in top journals such as Cell, Cancer Cell, Nature Genetics, Nature Biotechnology, and Nature Methods.
Dr. Liang has taken leadership roles in large cancer consortium projects, including chair of The Cancer Genome Atlas (TCGA) PanCanAtlas working groups, one co-leader of International Cancer Genome Consortium (ICGC) Pan-Cancer Whole Genome Analysis Project, and one co-chair of NCI Genomic Data Commons (GDC) QC working group. He won several awards including MD Anderson R. Lee Clark Fellow Award (2014), the University of Texas System STARS Award (2015), MD Anderson Faculty Scholar Award (2018), and AACR Team Science Award (2020). He is an elected Fellow of American Association for the Advancement of Science (AAAS).

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 28 Jan 2021 11:33:05 -0500 2021-02-10T16:00:00-05:00 2021-02-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Han Liang, PhD Professor and Deputy Chair, Department of Bioinformatics and Computational Biology Professor, Department of Systems Biology Barnhart Family Distinguished Professor in Targeted Therapies The University of Texas MD Anderson Cancer Center
DCM&B Tools and Technology Seminar (February 11, 2021 12:00pm) https://events.umich.edu/event/79915 79915-20515548@events.umich.edu Event Begins: Thursday, February 11, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Tool Link: https://micv.works

URL for Remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

(Disclosure: Nigel Michki is the founder and CEO of MiOmics Inc. (MI, USA))

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Livestream / Virtual Fri, 11 Dec 2020 08:01:07 -0500 2021-02-11T12:00:00-05:00 2021-02-11T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
Oral Health Sciences Seminar Series (February 11, 2021 12:00pm) https://events.umich.edu/event/81688 81688-20943436@events.umich.edu Event Begins: Thursday, February 11, 2021 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Lola Eniola-Adefeso, Ph.D.
University Diversity and Social Transformation Professor of Chemical Engineering
Vice-Chair for Graduate Studies in Chemical Engineering
Professor of Biomedical Engineering
Professor of Macromolecular Science and Engineering
Miller Faculty Scholar
Director, Cell Adhesion and Drug Delivery Lab
Associate Director, NIH Cellular Biotechnology Training Grant
University of Michigan

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Presentation Mon, 31 Jan 2022 10:25:38 -0500 2021-02-11T12:00:00-05:00 2021-02-11T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Presentation Lola Eniola-Adefeso, Ph.D.
UM Clinical Simulation Center Brown Bag Discussion (February 11, 2021 12:00pm) https://events.umich.edu/event/81701 81701-20943455@events.umich.edu Event Begins: Thursday, February 11, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Dr. Putnam will present a talk on "Novel use for Scenario Simulation: Real Life Resiliency."

Stressful and realistic simulation scenarios are common, and considered beneficial for learners.

We used an Operating Room case-gone-wrong to examine the impact of stress and the emotional impact of clinical practice. Our project used physicians, clinical psychologist and an educational specialist to deliver a semi-structured debrief to residents. We evaluated their experience.

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Lecture / Discussion Wed, 03 Feb 2021 14:51:03 -0500 2021-02-11T12:00:00-05:00 2021-02-11T13:00:00-05:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion
BME 500 Seminar: Gloria Kim (February 11, 2021 4:00pm) https://events.umich.edu/event/81383 81383-20889814@events.umich.edu Event Begins: Thursday, February 11, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Seminar Abstract:

The major problems in the current therapy for oncologic diseases include its inability to selectively target specific tumor cells in the surrounding tissues that make it hard for the drugs and treatment to reach the tumor cells. Despite the significant progress in the discovery of surface markers, targeting ligands, and biomaterial carriers, very few nanoparticle drugs are truly tumor-specific after intravenous injection and their targeting is still not fully reliable, which results in a wide distribution of nanoparticles throughout the body and increases the chance of adverse side effects. To overcome such limitations, my graduate research implemented immune cells as living targeting and delivery vehicles that deliver therapeutic biodegradable photoluminescent polymer (BPLP)-based nanoparticles to two tumor models, melanoma and glioblastoma. This system takes advantage of the inherent targeting and penetrating capabilities of immune cells into the tumor target and the fluorescent properties of BPLP nanoparticles for in vivo imaging. Our platform technology allows assembling various types of nanoparticles, drugs, imaging agents, and immune cells as a treatment for different diseases in the future. The second part of the seminar introduces how the immune cells can also be genetically engineered for cancer immunotherapy in vivo. Even with huge success in the development of CD19-targeting chimeric antigen receptor (CAR) T cells for B-cell hematological malignancies, we still face major challenges in expanding adoptive cell transfer for solid tumors. To expand this adoptive cell therapy, finding the right targets for solid tumors that are tumor- and tumor microenvironment-specific is the foremost important step. During my postdoctoral work, we have found an epitope within the collagen alpha-3(VI) (COL6A3) gene, which can be used as a biomarker to target stromal cells associated with multiple solid tumors. COL6A3-specific TCRs were isolated and one of these TCRs was affinity enhanced so that the T cells expressing TCR variants that preserved COL6A3 specificity and endowed both CD4 and CD8 T cells with augmented effector functions were able to specifically eliminate tumors in vivo that expressed similar amount of peptide-human leukocyte antigen (pHLA) as primary tumor specimens with favorable safety profile with no detectable off-target reactivity. These preclinical findings serve as the basis and rationale to initiate clinical trials using COL6A3-specific TCRs to target an array of solid tumors. As a principal investigator, my lab will first focus on merging immunology, synthetic biology, genetic engineering, material science, and biomedical engineering to develop and evaluate the next generation T cell-based therapies that target and kill solid tumors with enhanced specificity, reduced toxicity, and the ability to overcome tumor-associated immunosuppression.

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Lecture / Discussion Fri, 05 Feb 2021 16:15:40 -0500 2021-02-11T16:00:00-05:00 2021-02-11T17:00:00-05:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Innovations in Relating Real Life Exposures to Chemicals and Chemical Mixtures to Health Outcomes (February 12, 2021 1:00pm) https://events.umich.edu/event/79684 79684-20454248@events.umich.edu Event Begins: Friday, February 12, 2021 1:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Tentative Symposium Schedule

1:00-1:05 - Introduction
1:05-1:30 - Dr. Andreas Kortenkamp, Brunel University: “Male reproductive health – a bad cocktail of endocrine disruptors”
1:30-1:55 - Dr. Jodi Flaws, University of Illinois at Urbana-Champaign: “Applying real life phthalate mixtures from an Illinois pregnancy cohort to toxicological models”
1:55-2:20 - Dr. Laura Vandenberg, University of Massachusetts Amherst: “The mammary gland is a sensitive organ: lessons learned from fracking chemical mixtures”
2:00-2:55 - Dr. Paul Fowler, University of Aberdeen: “Exposure to the complex mixture of environmental chemicals found in human biosolids”
2:55-3:20 - Dr. Jyotsna Jagai, University of Illinois at Chicago: “Cumulative environmental quality and diabetes rates and control”
3:20-3.35 - Questions
3:35-4:00 - Panel Discussion, featuring: Dr. Jennifer McPartland, Environmental Defense Fund, Dr. Natalie Sampson, University of Michigan, Dr. Zorimar Rivera-Núñez, Rutgers University

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Workshop / Seminar Mon, 11 Jan 2021 09:15:50 -0500 2021-02-12T13:00:00-05:00 2021-02-12T16:00:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Workshop / Seminar FLYER_20210212_Symposium
RNA Seminar featuring: Karla Neugebauer, Yale University School of Medicine (February 15, 2021 4:00pm) https://events.umich.edu/event/78295 78295-20004839@events.umich.edu Event Begins: Monday, February 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

ZOOM REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_aZggyZ0yQcSPcJrsHloXjQ

ABSTRACT: My lab is interested in the coordination between transcription, RNA processing and nuclear organization that governs gene expression. We have established experimental systems in budding yeast, zebrafish embryos, and mammalian tissue culture cells to explore transcription and splicing regulation in a variety of biological contexts and with a diversity of tools, from imaging to genome-wide approaches. Our observations have provided novel insights into transcription and splicing mechanisms as well as principles of cellular organization that facilitate efficient gene expression. In this talk, I will be discussing rapid co-transcriptional splicing during erythropoiesis and how Cajal bodies assemble to ensure a steady supply of spliceosomal components.

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Lecture / Discussion Tue, 02 Feb 2021 16:32:41 -0500 2021-02-15T16:00:00-05:00 2021-02-15T17:00:00-05:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Prof. Karla Neugebauer, Ph.D.
Mental Health Perspectives During the COVID-19 Pandemic (February 16, 2021 10:00am) https://events.umich.edu/event/80038 80038-20548982@events.umich.edu Event Begins: Tuesday, February 16, 2021 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

As the pandemic continues without a specific end in sight, many of us here and around the world continue to struggle emotionally. Two experts will shed light on how those struggles are manifesting themselves today and what we can anticipate in the mental health realm going forward. Dr. Sheria Robinson-Lane will focus on pandemic impacts in older adults. Dr. Sheila Marcus will speak to mental health implications of the pandemic on adults and children as well as strategies for managing associated ongoing stress.

Speaker Sheria Robinson-Lane, PhD, RN, is a gerontologist with expertise in palliative care, long-term care, and nursing administration. She has focused her career on the care and support of older adults with cognitive and/ or functional disabilities. Dr. Robinson-Lane is interested in the ways that older adults adapt to changes in health, and particularly how adaptive coping strategies effect health outcomes. Her research is focused on reducing health disparities or minority older adults with cognitive impairments and their informal caregivers. Prior to coming to coming to the University of Michigan School of Nursing, Dr. Robinson-Lane completed an NIH- funded advanced research rehabilitation training program in community living and participation with the University of Michigan Medical School.

Speaker Sheila M. Marcus, MD, is a Clinical Professor in the UM Department of Psychiatry and Division head of Child and Adolescent Psychiatry. She leads a statewide program MC3 which assists primary care providers throughout the state in caring for individuals with mental health concerns. During COVID pandemic, she has assisted primary care providers and first-line providers with psychological first aid and balancing the stress of the pandemic with work and home obligations.

NO REGISTRATION REQUIRED

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Class / Instruction Tue, 15 Dec 2020 16:47:29 -0500 2021-02-16T10:00:00-05:00 2021-02-16T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Urgent and Critical Lectures
Key Legal Cases in Medical Ethics / Ethics of Human Research (February 17, 2021 10:00am) https://events.umich.edu/event/79832 79832-20507639@events.umich.edu Event Begins: Wednesday, February 17, 2021 10:00am
Location: Off Campus Location
Organized By: Osher Lifelong Learning Institute (50+)

This event is part three of the three part "Medical Ethics 101" lecture series.

Our speaker is Edward Goldman, J.D.., a practicing attorney and faculty member of the University of Michigan Medical School.

Preregistration is required via the OLLI website or phone. A link to access the presentation will be e-mailed to you approximately one week prior to the event.

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Class / Instruction Thu, 10 Dec 2020 08:30:23 -0500 2021-02-17T10:00:00-05:00 2021-02-17T11:30:00-05:00 Off Campus Location Osher Lifelong Learning Institute (50+) Class / Instruction Special Event
Improving the Evidence to Practice Gap through Innovation in Health Science Education (February 17, 2021 3:00pm) https://events.umich.edu/event/81403 81403-20893762@events.umich.edu Event Begins: Wednesday, February 17, 2021 3:00pm
Location: Off Campus Location
Organized By: RISE (Research. Innovation. Scholarship. Education.)

Please join us on Wednesday, February 17, 2021, 3:00 - 4:00 PM for a discussion on Improving the Evidence to Practice Gap through Innovation in Health Science Education.

Register for the event via Eventbrite: https://www.eventbrite.com/e/rise-virtual-talking-circle-tickets-130006826919

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Workshop / Seminar Thu, 28 Jan 2021 06:37:46 -0500 2021-02-17T15:00:00-05:00 2021-02-17T16:00:00-05:00 Off Campus Location RISE (Research. Innovation. Scholarship. Education.) Workshop / Seminar RISE Virtual Talking Circle
Special Joint Seminar between our Department and the Genome Science Training Program (February 17, 2021 4:00pm) https://events.umich.edu/event/80415 80415-20719669@events.umich.edu Event Begins: Wednesday, February 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The human genome sequence folds in three dimensions (3D) into a rich variety of locus-specific contact patterns. Despite growing appreciation for the importance of 3D genome folding in evolution and disease, we lack models for relating mutations in genome sequences to changes in genome structure and function. Towards that goal, we discovered that the organization of gene regulatory domains within chromosomes and the specific sequences that sit at boundaries between domains are under strong negative selection in the human population and over primate evolution. Motivated by this signature of functional importance, we developed a deep convolutional neural network, called Akita, that accurately predicts genome folding from DNA sequence alone. Representations learned by Akita underscore the importance of the structural protein CTCF but also reveal a complex grammar beyond CTCF binding sites that underlies genome folding. Akita enabled rapid in silico predictions for effects of sequence mutagenesis on the 3D genome, including differences in genome folding across species and in disease cohorts, which we are validating with CRISPR-edited genomes. This prediction-first strategy exemplifies my vision for a more proactive, rather than reactive, role for data science in biomedical research.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

Short bio: Dr. Katherine S. Pollard is Director of the Gladstone Institute of Data Science & Biotechnology, Investigator at the Chan Zuckerberg Biohub, Professor in the Department of Epidemiology & Biostatistics and Bioinformatics Graduate Program at UCSF. Her lab develops statistical models and open source bioinformatics software for the analysis of massive genomic datasets. Previously, Dr. Pollard was an assistant professor in the University of California, Davis Genome Center and Department of Statistics. She earned her PhD in Biostatistics from the University of California, Berkeley and was a comparative genomics postdoctoral fellow at the University of California, Santa Cruz. She was awarded the Thomas J. Watson Fellowship, the Sloan Research Fellowship, and the Alumna of the Year from UC Berkeley. She is a Fellow of the International Society for Computational Biology and of the California Academy of Sciences.

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Livestream / Virtual Wed, 06 Jan 2021 09:24:05 -0500 2021-02-17T16:00:00-05:00 2021-02-17T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Katherine S. Pollard, PhD (Director, Gladstone Institute of Data Science & Biotechnology; Professor, UCSF; Investigator, Chan Zuckerberg Biohub)
DCM&B Tools and Technology Seminar (February 18, 2021 12:00pm) https://events.umich.edu/event/79916 79916-20515549@events.umich.edu Event Begins: Thursday, February 18, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Tool Link: https://github.com/hhabra/metabCombiner

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Wed, 20 Jan 2021 11:08:42 -0500 2021-02-18T12:00:00-05:00 2021-02-18T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
Looking Ahead at Healthcare: What to Expect From The New Administration (February 18, 2021 12:00pm) https://events.umich.edu/event/82045 82045-21012683@events.umich.edu Event Begins: Thursday, February 18, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Ross

We are excited to be hosting our third event in The Business of Healthcare webinar series on Thursday, February 18. Join Tom Buchmueller, Ross School of Business, as he moderates a conversation with panelists Katie Keith and Joanne Kenen on Looking Ahead at Healthcare: What to Expect From The New Administration.

February 18, 2021
12:00pm - 1:15pm EST

Tom Buchmueller, PhD
Waldo O. Hildebrand Professor of Risk Management and Insurance; Professor of Business Economics and Public Policy, Michigan Ross

Katie Keith, J.D., M.P.H.
Principal, Keith Policy Solutions LLC; Adjunct Professor of Law, Georgetown University Law Center

Joanne Kenen
Editor At Large, Health Care at POLITICO

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Lecture / Discussion Fri, 12 Feb 2021 11:46:11 -0500 2021-02-18T12:00:00-05:00 2021-02-18T13:15:00-05:00 Off Campus Location Michigan Ross Lecture / Discussion
Reproductive Health and Justice: Context and Care of Incarcerated Women (February 18, 2021 12:00pm) https://events.umich.edu/event/81939 81939-20990923@events.umich.edu Event Begins: Thursday, February 18, 2021 12:00pm
Location:
Organized By: MI MED Scholars

You are invited to the first talk of the Incarceration and Health Lecture Series with Dr. Deb Landis Lewis, Associate Program Director for the OB/Gyn residency at Saint Joseph Mercy Hospital.

Reproductive Health and Justice: Context and Care of Incarcerated Women
Thursday, February 18, 12-1 pm

RSVP required: https://docs.google.com/forms/d/e/1FAIpQLSdT7MeIJpYqXQB6_pdq9MNUiD1uqOdg7Jp3tziCsU_hVZ2XAA/viewform

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Lecture / Discussion Tue, 09 Feb 2021 17:10:37 -0500 2021-02-18T12:00:00-05:00 2021-02-18T13:00:00-05:00 MI MED Scholars Lecture / Discussion Lecture flyer
Powering through Uncertainty (February 18, 2021 1:00pm) https://events.umich.edu/event/80885 80885-20816994@events.umich.edu Event Begins: Thursday, February 18, 2021 1:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Platform Architect, Intel & Founder, Timouns

Dr. Simon is a biomedical engineer, author and inventor who graduated from the University of Michigan Biomedical Engineering PhD program and was a School of Dentistry T32-TEAM Training Grant trainee. Her keynote seminar titled "Powering through Uncertainty" will encourage and inspire our students, faculty and staff as we strive to meet our mission of advancing health through education, service, research and discovery.

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Livestream / Virtual Mon, 18 Jan 2021 14:05:48 -0500 2021-02-18T13:00:00-05:00 2021-02-18T14:00:00-05:00 Off Campus Location Office of Research School of Dentistry Livestream / Virtual Keynote Speaker, Arlyne Simon
EIHS Lecture: Risk, Bodies, and Disease: Transatlantic Slavery and the History of Science and Medicine (February 18, 2021 4:00pm) https://events.umich.edu/event/79650 79650-20438368@events.umich.edu Event Begins: Thursday, February 18, 2021 4:00pm
Location: Off Campus Location
Organized By: Eisenberg Institute for Historical Studies

This talk will examine the history of the slave trade in the Iberian Atlantic and its relationship to the emergence of novel practices related to the study and quantification of bodies and nature. Specifically, it will discuss the development of ideas about the human body, population, and disease that appeared in Iberian-Atlantic slave markets during the sixteenth and seventeenth centuries. The practices undergirding the development of the slave trade as a technological, bureaucratic, economic, legal, and intellectual enterprise went hand in hand with the appearance of new notions about risk, disease, nosology, and population health that would become normative in subsequent decades. In analyzing the invisibility of both this history and the archives of the slave trade in traditional HSMT narratives, this lecture will also examine the role that ideas about knowledge (and what constitutes knowledge) have had in shaping fundamental and exclusionary tenets in the histories of science and Medicine in Euro America.

Pablo F. Gómez is associate professor in the Department of Medical History and Bioethics, and the Department of History at the University of Wisconsin-Madison. He works on histories of knowledge-making, race, and health and corporeality with a particular focus on Latin America, the Caribbean, and more largely the African Diaspora. His book The Experiential Caribbean Creating Knowledge and Healing in the Early Modern Atlantic, won the William H. Welch medal in medical history, the Albert J. Raboteau Book Prize in Africana religion, and Honorable Mention for the Bolton-Johnson Book Prize in Latin American history.

Free and open to the public. This is a remote event and will take place online via Zoom.

This event is part of the Thursday Series of the Eisenberg Institute for Historical Studies. It is made possible by a generous contribution from Kenneth and Frances Aftel Eisenberg.

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Lecture / Discussion Wed, 13 Jan 2021 10:07:50 -0500 2021-02-18T16:00:00-05:00 2021-02-18T17:00:00-05:00 Off Campus Location Eisenberg Institute for Historical Studies Lecture / Discussion Pablo F. Gómez
Science Success Series | Medical School Student Panel Discussion (February 18, 2021 6:30pm) https://events.umich.edu/event/80634 80634-20769609@events.umich.edu Event Begins: Thursday, February 18, 2021 6:30pm
Location: Off Campus Location
Organized By: Science Learning Center

Here is your chance to hear about what life is like for several medical school students and residents. Learn about each of their paths to medicine, experiences in various medical schools, and things they wished they had known in college.

Panelists:

Jasmine D.Johnson, M.D., FACOG/Clinical Instructor & Fellow UNC Department of Obstetrics & Gynecology/ Division of Maternal-Fetal Medicine

Eric Poole. Rising M3, Michigan State University College of Human Medicine

Register at: myumi.ch/Wwm09

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Workshop / Seminar Tue, 12 Jan 2021 12:14:31 -0500 2021-02-18T18:30:00-05:00 2021-02-18T19:30:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar book and stethoscope
LHS Collaboratory- February session (February 23, 2021 12:00pm) https://events.umich.edu/event/81035 81035-20838675@events.umich.edu Event Begins: Tuesday, February 23, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

The keynote presentation (12:00 pm-1:15 pm ET) will be followed by breakout sessions (1:15 pm-2:15 pm ET) on topics presented by the UM faculty and guests.
Zoom links to the individual breakout sessions are listed below.

Keynote speaker: Dr. Bernardo Mariano, Jr.
Topic: Digital Transformation in Healthcare for a Diverse World
Director of Digital Health & Innovation
Chief Information Officer (CIO)
World Health Organization (WHO)

Remarks:
Laurie McCauley, DDS, MS, PhD
Dean, William K and Mary Anne Najjar Professor of Periodontics
University of Michigan School of Dentistry


Breakout sessions from 1:15 pm-2:15 pm (ET)

Breakout Session #1 LHS and Pain
Zoom link: https://umich.zoom.us/j/99190944947

Topic: Integrating Diverse Health Ecosystems for
Optimal Pain Treatment, Education and Research
Alex F. DaSilva, DDS, DMedSc
University of Michigan School of Dentistry

Perspective: Data De‐Identification and Clinical Decision Support
Ivo Dinov, Ph.D.
Department of Health Behavior and Biological Sciences
University of Michigan


Breakout Session #2 LHS and Caries Risk
Zoom link: https://umich.zoom.us/j/97070468943

Topic: Caries Risk Prediction Models
Margherita Fontana, DDS, PhD
University of Michigan School of Dentistry

Perspective: LHS and Evidence-based Clinical Practice
Alonso Carrasco-Labra, DDS, MSc, PhD
Department of Evidence Synthesis and Translation Research
American Dental Association

Breakout Session #3 LHS and Opioids
Zoom link: https://umich.zoom.us/j/96029888703


Topic: Iteratively Learning about Dental Opioid Prescribing
Romesh Nalliah, BDS, MHCM
University of Michigan School of Dentistry

Perspective: Precision Health in Opioid Management
Chad Brummett, M.D.
University of Michigan Department of Anesthesiology

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Lecture / Discussion Thu, 21 Jan 2021 09:43:32 -0500 2021-02-23T12:00:00-05:00 2021-02-23T14:15:00-05:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory Logo
LRCCS Noon Lecture Series | Myth-Busting the History of Chinese Medicine: Going Beyond the "Function, Not Structure" Stereotype (February 23, 2021 12:00pm) https://events.umich.edu/event/80369 80369-20711696@events.umich.edu Event Begins: Tuesday, February 23, 2021 12:00pm
Location: Off Campus Location
Organized By: Lieberthal-Rogel Center for Chinese Studies

This talk will challenge the widely-held stereotype that Chinese doctors were historically interested in the body's dynamic functions, but indifferent to its anatomical structures. Using examples drawn from the history of Chinese traumatology during the 7th to 18th centuries, Dr. Wu will discuss the place of the physical and material body in Chinese medical thought and show how awareness of body structure was in fact intertwined with understandings of function.

Yi-Li Wu is an Associate Professor in the Department of Women’s and Gender Studies and the Department of History at the University of Michigan, Ann Arbor. Her research investigates the intersections of society, culture, and the body in the history of Chinese medicine, with special emphasis on the late imperial period (16th to 19th centuries). Her publications include “Reproducing Women: Medicine, Metaphor, and Childbirth in Late Imperial China” (University of California Press, 2010), as well as articles on medical illustration, forensic medicine, bone setting, breast cancer, and Chinese views of Western anatomical science. She is currently completing a book manuscript on the history of traumatology in China.

If there is anything we can do to make this event accessible to you, please contact us. Please be aware that advance notice is necessary as some accommodations may require more time for the university to arrange.

Zoom webinar; attendance requires registration: https://umich.zoom.us/webinar/register/WN_0ZIEkctzSKenwbE2FHcxEA

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Livestream / Virtual Wed, 13 Jan 2021 11:18:46 -0500 2021-02-23T12:00:00-05:00 2021-02-23T13:00:00-05:00 Off Campus Location Lieberthal-Rogel Center for Chinese Studies Livestream / Virtual LRCCS Noon Lecture Series | Myth-Busting the History of Chinese Medicine: Going Beyond the "Function, Not Structure" Stereotype
Toxic Equilibrium: Structural Racism and Population Health Inequities (February 24, 2021 10:00am) https://events.umich.edu/event/81748 81748-20949404@events.umich.edu Event Begins: Wednesday, February 24, 2021 10:00am
Location: Off Campus Location
Organized By: Institute for Social Research

February 24, 2021
10:00am – 6:30pm
Eastern Time

The American social structure is composed of a resilient, symbiotic network of the formal and informal institutions that operate to maintain an equilibrium toward White privilege. Across time and place, changes in one institution can reverberate through other institutions, and importantly, when we attempt to intervene toward equity in one institution, other institutions can move to restore this toxic equilibrium. Cultural racism, which encompasses the socially accepted ideologies, values, and behavioral norms determined by the dominant power group, sets this equilibrium. Particularly insidious as it operates on the level of our shared social subconscious, the processes that comprise cultural racism are invisible to many because they are our “givens”, our assumptions, our defaults – but the result shapes our answers to the question: Whose life counts?

For our 6th annual University of Michigan RacismLab Symposium on the Study of Racism, we pay tribute to the legacy of Dr. James Jackson, whose mentorship guided our 1st annual symposium in 2015 and resulted in our guest edited Social Science and Medicine special issue on cultural and structural racism. In the introduction to this special issue, we called for all scholarship on race and health to be grounded in interdisciplinary frameworks of cultural and structural racism and critical race theory.

Our annual symposium continues to be sponsored by the University of Michigan Survey Research Center at the Institute for Social Research. For our virtual meeting in 2021, we partner with the Interdisciplinary Association for Population Health Science (IAPHS) to move our discussions to a national stage. As we move to a national, interdisciplinary discussion, we are honored that a pioneer in the study of structural racism, Dr. Eduardo Bonilla Silva will serve as the keynote speaker this year.

Please register for this event: https://iaphs.org/tools-for-success/online-events/racismlab/racismlab-registration/

Event link will be provided upon registration.

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Conference / Symposium Wed, 17 Feb 2021 15:24:54 -0500 2021-02-24T10:00:00-05:00 2021-02-24T18:30:00-05:00 Off Campus Location Institute for Social Research Conference / Symposium poster
Crucial Conversations: Health Disparities and Social Inequities (February 24, 2021 12:00pm) https://events.umich.edu/event/82221 82221-21058452@events.umich.edu Event Begins: Wednesday, February 24, 2021 12:00pm
Location: Off Campus Location
Organized By: Public Engagement & Impact

For nearly a year, the COVID-19 pandemic has ravaged the United States. Black communities have found themselves disproportionately impacted by the virus and the unintended consequences of mitigation strategies.

This live discussion will bring together U-M experts and community members to engage in transparent and authentic dialogue on the realities of COVID-19, health disparities, and social inequities that Black communities face, and what can be done at U-M, and more broadly on a national scale, to address these issues.

Join via Zoom: myumi.ch/pdWgm
Watch Live: YouTube.com/UM

Moderator:
Dr. Oluwaferanmi O. Okanlami, MD, MS
Assistant Professor, Family Medicine, Physical Medicine & Rehabilitation, and Urology
Interim Director, Services for Students with Disabilities
Director, Adaptive Sports & Fitness

Panelists:
Dr. Matthew Wixson, MD
Clinical Assistant Professor, Anesthesiology
Associate Chair of Diversity, Department of Anesthesiology
Michigan Medicine

Dr. Jade Burns, PhD, RN, CPNP-PC
Assistant Professor, Health Behavior and Biological Sciences
School of Nursing

Kennedy Dubose
Community & Global Health Student, U-M School of Public Health ‘21

Arrice Bryant
MD/MPH Student, U-M Medical School ‘21
Michigan Medicine

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Livestream / Virtual Thu, 18 Feb 2021 08:55:46 -0500 2021-02-24T12:00:00-05:00 2021-02-24T13:00:00-05:00 Off Campus Location Public Engagement & Impact Livestream / Virtual Crucial Conversations: Health Disparities & Social Inequities Live Panel Discussion on Feb. 24 at 12pm. Panelists: Oluwaferanmi O. Okanlami, MD; Matthew Wixson, MD; Jade Burns, PhD; Kennedy Dubose; Arrice Bryant
CCMB / DCMB Weekly Seminar (February 24, 2021 4:00pm) https://events.umich.edu/event/82197 82197-21052530@events.umich.edu Event Begins: Wednesday, February 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: COVID Moonshot is an international consortium aiming to discover patent-free oral antiviral against SARS-CoV-2, targeting the main protease. Operating under an open science ethos, we make all data and structures publicly available, and crowdsource molecule designs from the community. In less than a year, we went from fragment hits to nanomolar leads in biochemical and antiviral assays. In my talk, I will discuss Moonshot’s journey towards orally bioavailable, non-covalent, and non-peptidomimetic Mpro inhibitors. I will discuss how machine learning technologies have accelerated our design-make-test cycle, and the learnings we gleaned from this large-scale prospective use of algorithms.

Bio: Dr. Alpha Lee is a Group Leader in the Department of Physics, University of Cambridge. His research focuses on developing machine learning technologies that close the design-make-test cycle for small molecule drug discovery and materials discovery. He is interested in how physical and chemical insights can be integrated into the design of interpretable algorithms. Before joining Cambridge, Dr. Lee was a Fulbright Scholar at Harvard and obtained his PhD from the University of Oxford.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 17 Feb 2021 13:18:31 -0500 2021-02-24T16:00:00-05:00 2021-02-24T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
DCM&B Tools and Technology Seminar (February 25, 2021 12:00pm) https://events.umich.edu/event/79917 79917-20515550@events.umich.edu Event Begins: Thursday, February 25, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 22 Jan 2021 12:31:37 -0500 2021-02-25T12:00:00-05:00 2021-02-25T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
Project Highlights from the 3D Innovations Lab - Deborah M. Rooney, PhD (March 3, 2021 9:00am) https://events.umich.edu/event/82680 82680-21161628@events.umich.edu Event Begins: Wednesday, March 3, 2021 9:00am
Location: Off Campus Location
Organized By: Clinical Simulation Center

All Michigan Medicine faculty and staff are invited to attend the next installment of the Clinical Simulation Center Brown Bag series.

The series is designed to promote collaboration and best practices in simulation-based education and research and will allow faculty, staff and learners the opportunity to learn and share best practices in simulation-based education and assessment.

The next event, which will be held virtually at noon on March 23rd in the CSC will discuss current projects in the 3D and Innovation Lab.

Attendees can meet the faculty and BME students who are solving simulation problems at Michigan Medicine.

Projects that will be discussed include:
- Development of a task trainer used to support cardiac surgery skills
- Development of a traumatic leg amputation model
- 3D Innovations Lab and Social Media

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Lecture / Discussion Wed, 03 Mar 2021 09:10:33 -0500 2021-03-03T09:00:00-05:00 2021-03-03T10:00:00-05:00 Off Campus Location Clinical Simulation Center Lecture / Discussion 2019-2020-3DI Lab TEAMclean
RNA Seminar featuring: Melissa Moore, Moderna Therapeutics (March 3, 2021 4:00pm) https://events.umich.edu/event/81265 81265-20879904@events.umich.edu Event Begins: Wednesday, March 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

**Please register here for March 3rd seminar: https://umich.zoom.us/webinar/register/WN_l0kt_NjpRh-f33LJj7KGpA

Dr. Moore will address scientists and non-scientists, and will take live questions.

In her role as Chief Scientific Officer, Platform Research, Dr. Melissa Moore is responsible for leading mRNA biology, delivery and computation science research at Moderna. She joined Moderna in 2016 from the University of Massachusetts Medical School, where she served as Professor of Biochemistry & Molecular Pharmacology, Eleanor Eustis Farrington Chair in Cancer Research and a long-time Investigator at the Howard Hughes Medical Institute (HHMI). Dr. Moore was also a founding Co-Director of the RNA Therapeutics Institute (RTI) at UMassMed, and was instrumental in creating the Massachusetts Therapeutic and Entrepreneurship Realization initiative (MassTERi), a faculty-led program intended to facilitate the translation of UMMS discoveries into drugs, products, technologies and companies. Dr. Moore is an elected member of the National Academy of Sciences (2017) and a Fellow of the American Academy of Arts and Sciences (2019).

Dr. Moore holds a B.S. in Chemistry and Biology from the College of William and Mary, and a Ph.D. in Biological Chemistry from MIT, where she specialized in enzymology under Prof. Christopher T. Walsh. She began working on RNA metabolism during her postdoctoral training with Phillip A. Sharp at MIT. During her 23 years as a faculty member, first at Brandeis and then at UMassMed, her research encompassed a broad array of topics related to the roles of RNA and RNA-protein (RNP) complexes in gene expression, and touched on many human diseases including cancer, neurodegeneration, and preeclampsia.

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Lecture / Discussion Wed, 10 Feb 2021 19:47:49 -0500 2021-03-03T16:00:00-05:00 2021-03-03T17:00:00-05:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Melissa Moore, Ph.D., Moderna Therapeutics
DCM&B Tools and Technology Seminar (March 4, 2021 12:00pm) https://events.umich.edu/event/79918 79918-20515551@events.umich.edu Event Begins: Thursday, March 4, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Tool link: https://github.com/rdcrawford/cognac

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 19 Feb 2021 14:34:43 -0500 2021-03-04T12:00:00-05:00 2021-03-04T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
BME 500 Seminar: Danielle Bassett (March 4, 2021 4:00pm) https://events.umich.edu/event/81388 81388-20889818@events.umich.edu Event Begins: Thursday, March 4, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

TBD

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Lecture / Discussion Wed, 27 Jan 2021 21:05:02 -0500 2021-03-04T16:00:00-05:00 2021-03-04T17:00:00-05:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Michigan India Conference (March 5, 2021 9:00am) https://events.umich.edu/event/82608 82608-21137865@events.umich.edu Event Begins: Friday, March 5, 2021 9:00am
Location: Off Campus Location
Organized By: Michigan India Conference

Have you heard the good news? The annual Michigan India Conference is back, and we’re going virtual for 2021.

We hope to see you there. We have a series of influential speakers you won’t want to miss! The theme for this year's conference is Stability & Change, so we have brought you the best decision-makers and thinkers surrounding India's government, India's economy and the Indian consumer. Get a chance to learn about the latest trends, opportunities, and maybe even a chance to network with some of India’s prestigious figures.

The Michigan India Conference gives business leaders, students, alumni, policymakers, and anyone interested, a chance to learn more about what drives this dynamic economy. Whether you are interested in doing business in India or want to learn more about policy and government, the Michigan India Conference is open to all. We hope you will join us.

Take advantage of our first fully-digital conference!
Register today: https://forms.gle/ug5R9KMKs1dXu28bA

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Conference / Symposium Tue, 09 Mar 2021 13:06:47 -0500 2021-03-05T09:00:00-05:00 2021-03-05T10:00:00-05:00 Off Campus Location Michigan India Conference Conference / Symposium Michigan India Conference
Bioethics Discussion: Infection (March 9, 2021 7:00pm) https://events.umich.edu/event/58838 58838-14563730@events.umich.edu Event Begins: Tuesday, March 9, 2021 7:00pm
Location: Off Campus Location
Organized By: The Bioethics Discussion Group

A discussion spreading to others.

Join us at: https://umich.zoom.us/j/99926126455.

A few readings to consider:
––Evidence and Effectiveness in Decision-Making for Quarantine
––The 1918 Influenza Pandemic: Insights for the 21st Century
––From SARS to Ebola: Legal and Ethical Considerations for Modern Quarantine
––Responding to the COVID-19 pandemic: Ethical considerations for conducting controlled human infection studies

For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/057-infection/.

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Feel free to stop by the website, not even the blog is viral: https://belmont.bme.umich.edu/incidental-art/

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Lecture / Discussion Fri, 08 Jan 2021 09:40:23 -0500 2021-03-09T19:00:00-05:00 2021-03-09T20:30:00-05:00 Off Campus Location The Bioethics Discussion Group Lecture / Discussion Infection
CCMB / DCMB Weekly Seminar Series (March 10, 2021 4:00pm) https://events.umich.edu/event/82479 82479-21108092@events.umich.edu Event Begins: Wednesday, March 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Single-cell technologies have transformed biomedical research in the last few years. With single-cell sequencing, we can now simultaneously measure thousands of genomics features in a large number of cells, which provides an ultrahigh resolution phenotypic map for each individual. However, single-cell protocols are complex. Even with the most sensitive platforms, the data are often sparse and noisy. Recent development of single-cell multi-omics and spatial transcriptomics technologies further imposed additional challenges on data integration. In this talk, I will present several machine learning methods that my group recently developed for single-cell and spatial transcriptomics data analysis. I will discuss methods for simultaneous denoising, clustering and batch effect correction, single-cell multi-omics data integration, identification of spatially variable genes, generation of super-resolution gene expression, and inference of cell type distribution in spatial transcriptomics. I will illustrate our methods by showing results from ongoing collaborations on cardiometabolic disease and applications to brain and cancer data.
* * *
Biography: Dr. Li’s research interests include statistical genetics and genomics, bioinformatics, and computational biology. The central theme of her current research is to use statistical and computational approaches to understand cellular heterogeneity in human-disease-relevant tissues, to characterize gene expression diversity across cell types, to study the patterns of cell state transition and crosstalk of various cells using data generated from single-cell and spatial transcriptomics studies, and to translate these findings to the clinics. In addition to methods development, Dr. Li is also interested in collaborating with researchers seeking to identify complex disease susceptibility genes and acting cell types. She is Director of Biostatistics for the Gene Therapy Program at Penn, where she advises biostatistics and bioinformatics analysis for various gene therapy studies. She is also Chair of the Graduate Program in Biostatistics. Dr. Li actively serves in the scientific community. She served as a regular member for the NIH Genomics, Computational Biology and Technology (GCAT) study section for 6 years, and the NHGRI Center for Inherited Disease Research (CIDR) for 3 years. She is an Associate Editor of Annals of Applied Statistics, Statistics in Biosciences, PLOS Computational Biology, and Human Genetics and Genomics Advances. She is an elected member of the International Statistical Institute and a Fellow of the American Statistical Association.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 24 Feb 2021 12:57:46 -0500 2021-03-10T16:00:00-05:00 2021-03-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
DCM&B Tools and Technology Seminar (March 11, 2021 12:00pm) https://events.umich.edu/event/79919 79919-20515552@events.umich.edu Event Begins: Thursday, March 11, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Genomic and epigenomic features are captured at a genome-wide level by using high-throughput sequencing technologies. Peak calling is one of the first essential steps in analyzing these features by delineating regions such as open chromatin regions and transcription factor binding sites. Our original peak calling software, F-Seq, has been widely used and shown to be the most sensitive and accurate peak caller for DNase I hypersensitive sites sequencing (DNase-seq) data. However, F-Seq lacks support for user-input control dataset nor reporting test statistics, limiting its ability to capture systematic and experimental biases and accurately estimate background distributions. Here we present an improved version, F-Seq2, which combined the power of kernel density estimation and a dynamic “continuous” Poisson distribution to robustly account for local biases and solve ties when ranking candidate peaks. In F-score and motif distance analysis, we demonstrated the superior performance of F-Seq2 than other competing peak callers used by the ENCODE Consortium on simulated and real ATAC-seq and ChIP-seq datasets. The output of F-Seq2 is suitable for irreproducible discovery rate (IDR) analysis as the test statistics calculated for individual candidate summit and ties are robustly solved.

Tool Link: https://github.com/Boyle-Lab/F-Seq2

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:08:59 -0500 2021-03-11T12:00:00-05:00 2021-03-11T13:00:00-05:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
BME 500 Seminar: George Christ (March 11, 2021 4:00pm) https://events.umich.edu/event/81389 81389-20889819@events.umich.edu Event Begins: Thursday, March 11, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Despite the well-documented capability of skeletal muscle to repair, regenerate, and remodel following injury, there remain a multitude of diseases, disorders, and traumatic injuries that result in irrecoverable loss of muscle structure and function. For example, volumetric muscle loss (VML) injuries are characterized by a degree of composite muscle tissue loss so severe, that it exceeds the native ability of the muscle to repair, thereby resulting in permanent cosmetic and functional deficits to the limbs, neck, or face. These injuries significantly impact both the civilian and military populations. Current treatment for VML injury involves surgical muscle transfer, although these procedures are often associated with both poor engraftment and donor site morbidity, as well as incomplete cosmesis and functional recovery. Not surprisingly, this unmet medical need has stimulated research efforts to develop new technologies for treatment of VML injuries. Recent attention has focused on development of tissue engineering (TE)/regenerative medicine (RM) technologies to provide more effective treatment options for large scale muscle injuries. A variety of preclinical approaches have been tried that include implantation of synthetic and/or natural extracellular matrices/scaffolds/constructs at the site of VML injury, both with and without a cellular component. Extant data indicate that the inclusion of a cellular component generally leads to a greater degree of functional improvement. Consistent with these preclinical results, recent clinical studies for treatment of VML injury, solely with implanted decellularized extracellular matrix scaffolds, have provided evidence for modest functional recovery but with little de novo muscle tissue regeneration at the injury site. More recently, bio-printed tissue engineered constructs and their potential applications to treatment of VML injury have been reported in the literature. While these initial clinical and preclinical observations are encouraging for the TE/RM paradigm, full structural and functional recovery has yet to be achieved, and thus, there remains significant room for therapeutic advancement. To this end, I will describe our highly collaborative efforts to boost development and evaluation of a range of implantable regenerative therapeutics (biomaterials and tissue engineered constructs) in biologically relevant animal models. The overall goal is to increase the efficiency of clinical translation of TE/RM technologies capable of more complete functional recovery following repair of VML injury.

ZOOM LINK: https://umich.zoom.us/j/94405051853

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Lecture / Discussion Mon, 08 Mar 2021 11:13:19 -0500 2021-03-11T16:00:00-05:00 2021-03-11T17:00:00-05:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Genes in Diseases and Symptoms Careers in Health Speaker Series (March 13, 2021 12:00pm) https://events.umich.edu/event/82457 82457-21102176@events.umich.edu Event Begins: Saturday, March 13, 2021 12:00pm
Location: Off Campus Location
Organized By: Genes in Diseases and Symptoms

Our GIDAS Careers in Health speaker series continues with Dr. Carl Koschmann from 12-1pm EST on Saturday, March 13th. If you’re interested, fill out this quick form and we will send the Zoom link.

Link: https://forms.gle/X7DdRsodaNsUtLoF8

Dr. Koschmann focuses on the care of children and young adults with brain tumors. He specializes in the research and treatment of children with high-risk brain tumors such as high-grade glioma and DIPG. His talk will be followed by a Q&A session.

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Lecture / Discussion Tue, 23 Feb 2021 18:46:12 -0500 2021-03-13T12:00:00-05:00 2021-03-13T13:00:00-05:00 Off Campus Location Genes in Diseases and Symptoms Lecture / Discussion Dr. Carl Koschmann Speaker Series Poster
RNA Seminar featuring: James Nuñez, HHMI Hanna Gray Fellow, University of California, San Francisco (March 15, 2021 4:00pm) https://events.umich.edu/event/81286 81286-20881887@events.umich.edu Event Begins: Monday, March 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_f8wC8rrJQzuhYzTEXoW69Q


ABSTRACT
General approaches for heritably altering gene expression would enable many discovery and therapeutic efforts. I will present CRISPRoff— a programmable epigenetic memory writer consisting of a single dead Cas9 fusion protein that establishes DNA methylation and repressive histone modifications to turn off transcription. Transient CRISPRoff expression initiates highly specific DNA methylation and gene repression that is maintained through cell division and differentiation of stem cells to neurons. Pairing CRISPRoff with genome-wide screens and analysis of chromatin marks enabled us to explore the rules for heritable silencing. We identify sgRNAs capable of silencing the large majority of genes including those lacking canonical CpG islands (CGIs) and reveal a wide targeting window extending beyond annotated CGIs. Our finding that targeted DNA methylation outside of CGIs leads to memorized gene silencing expands the canonical model of methylation-based silencing and broadly enables diverse applications including genome-wide screens, multiplexed cell engineering, enhancer silencing, and mechanistic exploration of epigenetic inheritance.

KEYWORDS: CRISPR, transcription, epigenetics
Flyer in PDF: https://rna.umich.edu/wp-content/uploads/2021/02/Seminar-Flyer-03152021-Nunez.pdf

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Lecture / Discussion Thu, 18 Feb 2021 09:21:31 -0500 2021-03-15T16:00:00-04:00 2021-03-15T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion James Nunez, Ph.D. UCSF
Innovations in Global Maternal Healthcare Delivery (March 15, 2021 5:00pm) https://events.umich.edu/event/82932 82932-21225228@events.umich.edu Event Begins: Monday, March 15, 2021 5:00pm
Location: Off Campus Location
Organized By: Center for the History of Medicine

Hi UMMS!

NextGen Med and the Society for the History and Philosophy of Medicine are excited to co-host an educational discussion on Monday, March 15th from 5-6PM via Zoom! Please join us for a talk and Q&A, "How Philanthropy Can Catalyze Innovation in Global Public Health: Maternal, Newborn, and Child Health Focuses in the Gates Foundation," with Program Officer Mrs. Anisha Gururaj.

Anisha Gururaj is a Program Officer at the Bill & Melinda Gates Foundation, in the Maternal Newborn Child Health, Discovery & Tools team, where she develops strategy and manages an investment portfolio focused on developing and delivering novel technologies, like digital health, AI, and connected diagnostics, to transform maternal and newborn health across sub-Saharan Africa and South Asia. Previously, she has worked for a wide variety of technology and public health-focused organizations, ranging from the Baltimore city health department to med device startups and large manufacturing companies. She has a B.S. in Chemical-Biological Engineering from MIT and a dual MSc in Global Governance & Diplomacy and Women's Health Sciences from the University of Oxford where she studied as a Rhodes Scholar.

Zoom link here: https://umich.zoom.us/j/93942689324
Meeting ID: 939 4268 9324

Hope to see you there!

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Livestream / Virtual Thu, 11 Mar 2021 12:50:14 -0500 2021-03-15T17:00:00-04:00 2021-03-15T18:15:00-04:00 Off Campus Location Center for the History of Medicine Livestream / Virtual
U-M Injury Prevention Center 2021 Suicide Prevention Summit (March 16, 2021 12:00pm) https://events.umich.edu/event/79634 79634-20436381@events.umich.edu Event Begins: Tuesday, March 16, 2021 12:00pm
Location: Off Campus Location
Organized By: U-M Injury Prevention Center

The University of Michigan Injury Prevention Center has organized a unique event to share the latest evidence-based suicide prevention research, facilitate new collaborations, and explore new ideas for suicide prevention.

Please visit this url for more information: https://www.eventbrite.com/e/the-science-of-suicide-prevention-tickets-128890714597

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Conference / Symposium Tue, 01 Dec 2020 11:14:38 -0500 2021-03-16T12:00:00-04:00 2021-03-16T17:00:00-04:00 Off Campus Location U-M Injury Prevention Center Conference / Symposium Suicide_Prevention_Summit
TSCA @ 5 Years: Opportunities to Act with Foresight (March 16, 2021 7:00pm) https://events.umich.edu/event/82485 82485-21108121@events.umich.edu Event Begins: Tuesday, March 16, 2021 7:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

The University of Michigan M-LEEaD Center is co-sponsoring an event to mark the 5-year anniversary of the bipartisan legislation called the Frank R. Lautenberg Chemical Safety for the 21st Century Act. This reform law was designed to modernize U.S. industrial chemical policy to promote health, but has it lived up to its promise?

Public understanding is limited regarding how exposures to toxic chemicals affect health and how they might be regulated. Unlike pharmaceuticals, industrial and commercial chemicals are rarely tested for safety before they reach the U.S. market. The 1976 TSCA has been widely acknowledged to be a weak and ineffective law, and widespread exposures and harms continue. In the U.S., everyone is exposed to industrial and toxic chemicals, dozens and probably hundreds – well before birth. The amount of chemicals manufactured and imported continues to grow – it is trillions of pounds – and these chemicals remain largely unregulated. At the same time, we have seen an increase in chronic diseases, such as diabetes, autism, and infertility. Not everyone is equally at risk, and a higher burden of disease falls on low wealth communities and communities of color. These health disparities in exposures and health effects are illustrated and exacerbated by COVID.

The amended TSCA gave the U.S. Environmental Protection Agency new requirements and authorities. The public health impact points to the need for the U.S. EPA to fully use its new powers to evaluate all risks from hazardous chemicals and set policies which protect health and are accountable to high-risk communities. Preventive actions are urgently needed.

Watch “THE FOREVER CHEMICALS” documentary (2019, 26 min) at Great Lakes Now then join the March 16 forum. https://www.greatlakesnow.org/fc
“The Forever Chemicals” is an Emmy-winning examination of the impact of PFAS contamination in west Michigan
communities.

LEARN MORE AT OUR LIVE VIRTUAL PANEL DISCUSSION (registration required) on March 16 with Sandra Svoboda, “The Forever Chemicals” co-producer and Great Lakes Now Program Director; Tracey Woodruff, PhD, MPH, Professor, Ob/Gyn, Reproductive Sciences, University of CA-San Francisco; and Justin Onwenu, Environmental Justice Organizer, Sierra Club. Moderated by Patricia Koman, MPP, PhD, Research Investigator, Environmental Health Sciences, University of Michigan with Welcoming remarks from Gilbert S. Omenn, MD, PhD, the Harold T Shapiro Distinguished University Professor of Medicine (also Professor of Computational Medicine & Bioinformatics; Internal Medicine; Human Genetics; and Public Health, Univ of Mich).

REGISTER HERE https://bit.ly/37I2JaU

SPONSORED BY the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) • U-M Environmental Health Sciences • Detroit Public Television • Wayne State CURES Center • U-M Sustainable Living Experience • UROP (U-M Undergraduate Research Opportunity Program) • UMIHSA (U-M Industrial Hygiene Students Association) • EHSA (Environmental Health Student Association) • American Chemical Society Outreach Organization • U-M Health Policy Student Association • Ecology Center • Michigan Environmental Justice Coalition • UCSF Program for Reproductive Health and the Environment • UCSF EaRTH Center

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Conference / Symposium Wed, 03 Mar 2021 12:57:09 -0500 2021-03-16T19:00:00-04:00 2021-03-16T20:30:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Conference / Symposium March 16 Panel Discussion: TSCA @ 5 Years
CCMB / DCMB Weekly Seminar Series featuring Sriram Chandrasekaran (Assistant Professor, Biomedical Engineering) (March 17, 2021 4:00pm) https://events.umich.edu/event/82825 82825-21179592@events.umich.edu Event Begins: Wednesday, March 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Drug combinations have the potential to greatly expand our pharmacopeia while reducing both cost and drug resistance. Yet the current drug-discovery approach is unable to screen the astronomical number of possible combinations in different cell types and does not account for the complex environment inside the body. We have developed AI tools - INDIGO and MAGENTA - that predict the efficacy of drug combinations based on the properties of the drugs, the pathogen, and the infection environment. We are also using modeling to identify drugs that work in synergy with the host immune system. Using INDIGO and MAGENTA, we have identified highly synergistic combinations of repurposed drugs to treat drug resistant infections including Tuberculosis, the deadliest bacterial infection. INDIGO also accurately predicts the outcome of past clinical trials of drug combinations. Our ultimate goal is to create a personalized approach to treat infections using AI.
* * *
Biography: Chandrasekaran received his bachelor’s degree in Biotechnology from Anna University in 2008, and a PhD in Biophysics from the University of Illinois at Urbana-Champaign in 2013. He worked at Harvard University and MIT as a Harvard Junior Fellow between 2013 and 2016 and became an Assistant Professor at UM in 2017. His lab develops systems biology algorithms for drug discovery. Computer models from his lab like INDIGO and MAGENTA are being used to design effective therapies against drug resistant pathogens. His lab also develops systems biology algorithms to understand metabolic regulation. The approaches that they have created (PROM, ASTRIX, DFA, EGEM and GEMINI) perform complementary functions in modeling of metabolic and regulatory networks. Chandrasekaran’s research has been published in Cell, Genome Biology, mBio, and PNAS. For his work, Chandrasekaran previously received the 2013 Harvard Junior Fellowship, the 2011 Howard Hughes Medical Institute (HHMI) International Predoctoral Fellowship, the 2014 William Milton Fund award, 2018 UM Precision Health Investigator Award, and the 2018 Distinguished Young Investigator Award from the AICHE COBRA society.


https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 05 Mar 2021 14:44:14 -0500 2021-03-17T16:00:00-04:00 2021-03-17T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Sriram Chandrasekaran, PhD (Assistant Professor, Biomedical Engineering)
DCM&B Tools and Technology Seminar (March 18, 2021 12:00pm) https://events.umich.edu/event/79920 79920-20515553@events.umich.edu Event Begins: Thursday, March 18, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Tool Link: WIZARD: https://github.com/ML4LHS/wizard
Tool Link: Clinspacy: https://github.com/ML4LHS/clinspacy
Tool Link: Runway: https://github.com/ML4LHS/runway

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:11:56 -0500 2021-03-18T12:00:00-04:00 2021-03-18T13:00:00-04:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
The Woll Family Speaker Series on Health, Spirituality and Religion presents (March 18, 2021 12:00pm) https://events.umich.edu/event/82727 82727-21169586@events.umich.edu Event Begins: Thursday, March 18, 2021 12:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

The Woll Family Speaker Series on Health, Spirituality and Religion presents

Christian Alch, MD, House Officer, Department of Internal Medicine, "Barriers to Addressing the Spiritual and Religious Needs of Patients and Families in the Intensive Care Unit: A Qualitative Study of Critical Care Physicians"

Abbass Berjaoui, Third Year Medical Student, Ruth Bishop, Third Year Medical Student, Elie Ellenberg, Fourth Year Medical Student, "Assessing the Spiritual Needs of Patients Awaiting Heart Transplantation" (Ruth Bishop to present)

Nabeel Salka, Fourth Year Medical Student, "Exploring Physician Identity from an Islamic and Contemporary Western Perspective"

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Workshop / Seminar Thu, 04 Mar 2021 09:14:06 -0500 2021-03-18T12:00:00-04:00 2021-03-18T13:00:00-04:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar
BME 500 Seminar: Daniel Rueckert (March 18, 2021 4:00pm) https://events.umich.edu/event/81390 81390-20889820@events.umich.edu Event Begins: Thursday, March 18, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Zoom Link: https://cwru.zoom.us/webinar/register/WN_tmHJ7ArQRyO01NN6SfYYtg

Hosted by Dr. Frederick Epstein

Seminar Abstract:
The talk will focus on the use of deep learning techniques for the discovery and quantification of clinically useful information from medical images. The talk will describe how deep learning can be used for the reconstruction of medical images from undersampled data, image super-resolution, image segmentation and image classification. It will also show the clinical utility of applications of deep learning for the interpretation of medical images in applications such as brain tumour segmentation, cardiac image analysis and applications in neonatal and fetal imaging. Finally, it will be discussed how deep learning may change the future of medical imaging. https://openbme.org/

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Lecture / Discussion Mon, 15 Mar 2021 14:07:10 -0400 2021-03-18T16:00:00-04:00 2021-03-18T17:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Michigan India Conference (March 19, 2021 9:00am) https://events.umich.edu/event/82608 82608-21137866@events.umich.edu Event Begins: Friday, March 19, 2021 9:00am
Location: Off Campus Location
Organized By: Michigan India Conference

Have you heard the good news? The annual Michigan India Conference is back, and we’re going virtual for 2021.

We hope to see you there. We have a series of influential speakers you won’t want to miss! The theme for this year's conference is Stability & Change, so we have brought you the best decision-makers and thinkers surrounding India's government, India's economy and the Indian consumer. Get a chance to learn about the latest trends, opportunities, and maybe even a chance to network with some of India’s prestigious figures.

The Michigan India Conference gives business leaders, students, alumni, policymakers, and anyone interested, a chance to learn more about what drives this dynamic economy. Whether you are interested in doing business in India or want to learn more about policy and government, the Michigan India Conference is open to all. We hope you will join us.

Take advantage of our first fully-digital conference!
Register today: https://forms.gle/ug5R9KMKs1dXu28bA

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Conference / Symposium Tue, 09 Mar 2021 13:06:47 -0500 2021-03-19T09:00:00-04:00 2021-03-19T10:00:00-04:00 Off Campus Location Michigan India Conference Conference / Symposium Michigan India Conference
Project Management Certification (March 21, 2021 12:00pm) https://events.umich.edu/event/80730 80730-20779512@events.umich.edu Event Begins: Sunday, March 21, 2021 12:00pm
Location: Off Campus Location
Organized By: Tauber Institute for Global Operations

Once again, the Tauber Institute, in conjunction with the International Project Management Association (IPMA), is sponsoring a Project Management certification class and exam for graduate business and engineering students and staff.

In order to participate, you will need to reflect upon a project management experience (for example: a work project, an engineering design experience/senior capstone, Ross' MAP project, Tauber team project, etc). If you cannot make it to the classes (due to project travel, MAP, or other another class), the sessions will be recorded. Homework (mastery verification) will be required after each session.

The cost to an individual to take the exam is normally $595, however, Tauber is offering the exam at a substantial discount to non-Tauber students:
$500 for U-M alumni or public
$400 for U-M students, U-M employees, or Tauber alumni
$200 for Tauber Institute students

Certification is valid for 5 years. Three certification classes will be taught by Professor Eric Svaan on the following dates:

Sunday, March 21 (noon - 4:30 pm)
Sunday, March 28 (noon - 4:30 pm)
Sunday, April 18 (noon - 4:30 pm)

The certification exam, administered by IPMA-USA is scheduled for May 12, 2021 (11:00 am) virtually. Successfully passing the exam will yield IPMA's Level D certification (Certified Project Management Associate).

Since 2013, all students who have taken the exam have passed!

Project Management is a powerful skill set to have in your toolbox as you look for full-time employment!

REGISTRATION: Please register through iMpact by clicking here:
https://www.bus.umich.edu/Conferences/Project-Management-Certification-2021/Default.aspx

NOTE: The non-refundable fees:
$500 for non-Tauber students, U-M alumni, or public
$400 for U-M students, U-M employees, or Tauber alumni
$200 for Tauber Institute students

HOSTED BY: Tauber Institute for Global Operations. For questions about this event, please contact tauberinstitute@umich.edu or visit tauber.umich.edu.

What is IPMA Level D® (Certified Project Management Associate)? The IPMA Level D is an internationally recognized entry-level qualification in the area of project management. This designation, which demonstrates the individual's ability to understand the basics of project management, is similar to the exam-oriented, knowledge-based certifications of other major Project Management associations. For many, Level D® is the first step towards a professional project or program manager role. It is the first step in a sequence (C, B and A) to be earned by demonstration of success in larger PM responsibility sets.

For more information,
Visit tauber.umich.edu or call 734-647-1333
Connect via email to Diana Crossley dianak@umich.edu

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Class / Instruction Tue, 19 Jan 2021 12:27:23 -0500 2021-03-21T12:00:00-04:00 2021-03-21T16:30:00-04:00 Off Campus Location Tauber Institute for Global Operations Class / Instruction Certificate photo
Concussion Prevention: A Multi-Disciplinary Approach (March 24, 2021 11:30am) https://events.umich.edu/event/83111 83111-21272914@events.umich.edu Event Begins: Wednesday, March 24, 2021 11:30am
Location: Off Campus Location
Organized By: U-M Office of Research

Please join the Michigan Exercise & Sport Science Initiative and the University of Michigan Concussion Center on Wednesday, March 24, 2021, at 11:30am for a panel discussion focusing on concussion prevention. You will learn concussion prevention methods from experts in athlete conditioning, equipment manufacturing, and sports policy at the state, national, and international levels.

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Lecture / Discussion Wed, 17 Mar 2021 10:43:41 -0400 2021-03-24T11:30:00-04:00 2021-03-24T12:30:00-04:00 Off Campus Location U-M Office of Research Lecture / Discussion Concussion
Where Do We Go From Here: Body Politics & Movement Towards Racial Empowerment (March 24, 2021 12:00pm) https://events.umich.edu/event/82828 82828-21179596@events.umich.edu Event Begins: Wednesday, March 24, 2021 12:00pm
Location: Off Campus Location
Organized By: School of Kinesiology

Please join us for the last event in our series addressing the theme: "Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment."

This event will consist of a panel featuring scholars and medical, mental health, and fitness experts discussing movement, and physical and mental wellness/well-being as ways of combatting the body politics of racism. The event will include panelists’ demonstrations and audience participation.

If you'd like to join along with the Afrobeats dance demonstration (and we hope you do), please wear comfortable clothes and use a space where you have room to move. All ages and abilities are welcome; no experience needed!

--Abigail Eiler, LMSW, MSW, QMHP: Clinical Assistant Professor, U-M School of Social Work; Director, Athletics Counseling, U-M Athletics; Chair, Mental Health & Wellness Cabinet, Big Ten Conference

--Chiamaka Ukachukwu, MS: PhD Candidate (Specializing in Cardiovascular Electrophysiology), U-M Department of Pharmacology; Afrobeats Dance Instructor, U-M Recreational Sports

--Dr. Kamaria Washington, DPT: Physical Therapist (Specializing in Pelvic Floor Concerns), Therapeutic Associates Bethany Physical Therapy (Portland, OR)

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Well-being Wed, 17 Mar 2021 17:58:46 -0400 2021-03-24T12:00:00-04:00 2021-03-24T13:30:00-04:00 Off Campus Location School of Kinesiology Well-being U-M Health Sciences - Where Do We Go From Here: Body Politics & Movement Towards Racial Empowerment
James S. Jackson’s Continuing Legacy and Contributions to Social and Behavioral Research on Black Americans (March 24, 2021 1:00pm) https://events.umich.edu/event/82484 82484-21108104@events.umich.edu Event Begins: Wednesday, March 24, 2021 1:00pm
Location: Off Campus Location
Organized By: Institute for Social Research

ISR Insights Speaker Series – James S. Jackson’s Continuing Legacy and Contributions to Social and Behavioral Research on Black Americans

Wednesday, March 24, 1pm EST. https://umich.zoom.us/j/99879554198

Panelists: Robert Taylor (Harold R Johnson Endowed Professor of Social Work, Sheila Feld Collegiate Professor of Social Work, School of Social Work, and Faculty Associate, RCGD); Belinda Tucker (Professor Emerita of Psychiatry & Biobehavioral Sciences, and the Special Liaison for Faculty Development, UCLA); and Phillip Bowman (Professor, Higher and Postsecondary Education at the U-M International Institute)

Join Robert Taylor, Belinda Tucker, and Phillip Bowman for a panel discussion on the continuing legacy and contributions of James S. Jackson.

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Lecture / Discussion Wed, 24 Feb 2021 16:45:04 -0500 2021-03-24T13:00:00-04:00 2021-03-24T14:00:00-04:00 Off Campus Location Institute for Social Research Lecture / Discussion event flyer
CCMB / DCMB Weekly Seminar Series Featuring Duncan K. Ralph (Fred Hutchinson Cancer Research Center) (March 24, 2021 4:00pm) https://events.umich.edu/event/82733 82733-21169592@events.umich.edu Event Begins: Wednesday, March 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Antibodies are an integral part of the adaptive immune response, and are a critical component of both vaccine-induced and naturally-acquired immunity. The development of deep sequencing approaches in recent years has allowed us to sample a significant fraction of the diverse repertoire of B cell receptor sequences from which antibodies are made. These sequences encode a wealth of information on the somatic rearrangement and evolutionary processes that determine the contours of our antibody repertoires, and thus our ability to respond appropriately to pathogens and vaccines. Extracting this information, however, requires a careful inference approach across several different analysis steps. I will describe the computational approaches that we have taken to solving these problems, which constitute the partis software package, and describe their application in several projects, including HIV and Dengue data.

* * *

Biography: Duncan attended the University of California at Santa Cruz for his undergraduate studies in physics, completing his thesis on energy transport in condensed matter theory in 2005. He completed his PhD at the Massachusetts Institute of Technology in 2014, working on the Large Hadron Collider at the European particle physics laboratory (CERN). His thesis described the observation of Higgs boson decays to four leptons. Since 2014, he has worked in Frederick Matsen’s lab at the Fred Hutchinson Cancer Research Center, first as a postdoctoral researcher and more recently as a staff scientist, writing new computational methods for the analysis of B cell receptor deep sequencing data.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 04 Mar 2021 11:20:24 -0500 2021-03-24T16:00:00-04:00 2021-03-24T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Designing for Impact in Global Health (March 24, 2021 5:00pm) https://events.umich.edu/event/82821 82821-21179589@events.umich.edu Event Begins: Wednesday, March 24, 2021 5:00pm
Location: Off Campus Location
Organized By: Center for Global Health Equity

Please join us for the next seminar for the UM Center for Global Health Equity: Designing for Impact in Global Health.

Panelists include:
Kathleen Sienko, College of Engineering
Paul Clyde, William Davidson Institute
Rocky Oteng, School of Medicine
Kentaro Toyama, School of Information
Grace Burleson, College of Engineering
David Green, Social Entrepreneur
Jesse Austin-Breneman, College of Engineering

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Workshop / Seminar Fri, 05 Mar 2021 14:12:00 -0500 2021-03-24T17:00:00-04:00 2021-03-24T18:30:00-04:00 Off Campus Location Center for Global Health Equity Workshop / Seminar Panelists
5th Annual RNA Symposium, "Processing RNA" (March 25, 2021 11:00am) https://events.umich.edu/event/80161 80161-20572609@events.umich.edu Event Begins: Thursday, March 25, 2021 11:00am
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

FOR MORE DETAILS & ABSTRACTS VISIT: https://rna.umich.edu/2021-symposium/

Thursday, March 25, 2021
11:00 / Welcome
11:05 / KEYNOTE 1: Tracy Johnson, UCLA, “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression”
12:00 / Short break
12:10 / KEYNOTE 2: Kevin Weeks, UNC, “Structure-Based Discovery of New Functions in Large RNAs”
1:05 / Data Blitz: Cathy Smith, Daniel Peltier, Yan Zhang
1:35 / KEYNOTE 3: Feng Zhang, MIT, “Exploration of Biological Diversity to Discover Novel Molecular Technologies”
2:30 / Close Day 1

Friday, March 26, 2021
11:00 / Welcome
11:05 / KEYNOTE 4: Brenda Bass, University of Utah, “Distinguishing self and non-self dsRNA in vertebrates and invertebrates”
12:00 / Short break
12:10 / KEYNOTE 5: Christopher Lima, Sloan-Kettering Institute, “Mechanisms that target RNA for destruction”
1:05 / Data Blitz: Meredith Purchal, Adrien Chauvier, Shannon Wright
1:35 / Panel discussion with keynote speakers
2:30 / Close Day 2

Liveblogging by MiSciWriters! https://misciwriters.com/

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Lecture / Discussion Tue, 23 Mar 2021 15:03:26 -0400 2021-03-25T11:00:00-04:00 2021-03-25T14:30:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion 5th Annual RNA Symposium
DCM&B Tools and Technology Seminar (March 25, 2021 12:00pm) https://events.umich.edu/event/82051 82051-21012687@events.umich.edu Event Begins: Thursday, March 25, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

(please note that this session will not be recorded)

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Workshop / Seminar Tue, 23 Mar 2021 17:42:45 -0400 2021-03-25T12:00:00-04:00 2021-03-25T13:00:00-04:00 Off Campus Location DCMB Tools and Technology Seminar Workshop / Seminar
LHS Collaboratory March Session (March 25, 2021 12:00pm) https://events.umich.edu/event/82008 82008-21006745@events.umich.edu Event Begins: Thursday, March 25, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Speakers Stefan Boes, PhD and Sarah Mantwill, PhD from the university of Lucerne will discuss the Swiss Learning Health System.

Promoting and supporting uptake of evidence and evidence-informed decision-making in health-systems related policy and practice is a challenge. In Switzerland, the need to address this matter has been increasingly emphasized by different actors in the health system. In particular, the lack of comprehensive coordination efforts in the field of health services research, and subsequent knowledge translation activities, has been stressed. In response, the Swiss Learning Health System (SLHS) was established as a nationwide project in 2017, currently involving 10 academic partner institutions. One of the overarching objectives of the SLHS is to bridge research, policy, and practice by providing an infrastructure that supports learning cycles by: continuously identifying issues relevant to the Swiss health system, systemizing relevant evidence, presenting potential courses of action, and revising and reshaping responses. Key features of learning cycles in the SLHS include the development of policy/evidence briefs that serve as a basis for stakeholder dialogues with actors from research, policy and practice. Issues that are identified to be further pursued are monitored for potential implementation and eventually evaluated to inform new learning cycles and to support continuous learning within the system.

Dr. Boes and Dr. Mantwill will provide an overview of the SLHS and its key features, as well as its capacity building efforts to train young researchers in the field of learning health systems, and the development of a centralized metadata repository in support of creating a sufficient large evidence basis to support learning cycles in the Swiss health system. Further, they will discuss lessons learned from the past and the newest developments of the SLHS in light of a second funding phase supported by the Swiss government.

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Livestream / Virtual Thu, 25 Feb 2021 23:57:27 -0500 2021-03-25T12:00:00-04:00 2021-03-25T13:30:00-04:00 Off Campus Location Department of Learning Health Sciences Livestream / Virtual LHS Collaboratory Logo
BME 500 Seminar: Warren L. Grayson (March 25, 2021 4:00pm) https://events.umich.edu/event/81391 81391-20889821@events.umich.edu Event Begins: Thursday, March 25, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Tissue engineering provides a viable means of regenerating bone and skeletal muscle tissues following injuries that lead to large volumetric defects. Our lab has developed advanced biomaterial and stem cell-based approaches to promote functional recovery following volumetric muscle loss and critical-sized craniofacial bone injuries. This presentation will focus on three areas of ongoing research: (1) I will present our lab’s efforts to regenerate vascularized and innervated skeletal muscle in mice including our recent studies using human pluripotent stem cells. (2) Recently, our group completed a study focused on designing biomaterials to guide bone regeneration in situ in minipigs using intraoperative protocols for combining autologous stem cells with 3D-printed scaffolds. (3) Understanding the interaction between vascular cells and osteoprogenitors is critical for developing effective treatment methods. I will describe recent studies in which we developed a quantitative imaging platform for characterizing the spatial relationships between cell populations in the native murine calvarium. https://openbme.org/

ZOOM LINK TO REGISTER: https://cwru.zoom.us/webinar/register/WN_Kgyl3yf4TcKvlk9xNKluhA

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Lecture / Discussion Sun, 21 Mar 2021 17:46:23 -0400 2021-03-25T16:00:00-04:00 2021-03-25T17:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Michigan India Conference (March 26, 2021 9:00am) https://events.umich.edu/event/82608 82608-21137867@events.umich.edu Event Begins: Friday, March 26, 2021 9:00am
Location: Off Campus Location
Organized By: Michigan India Conference

Have you heard the good news? The annual Michigan India Conference is back, and we’re going virtual for 2021.

We hope to see you there. We have a series of influential speakers you won’t want to miss! The theme for this year's conference is Stability & Change, so we have brought you the best decision-makers and thinkers surrounding India's government, India's economy and the Indian consumer. Get a chance to learn about the latest trends, opportunities, and maybe even a chance to network with some of India’s prestigious figures.

The Michigan India Conference gives business leaders, students, alumni, policymakers, and anyone interested, a chance to learn more about what drives this dynamic economy. Whether you are interested in doing business in India or want to learn more about policy and government, the Michigan India Conference is open to all. We hope you will join us.

Take advantage of our first fully-digital conference!
Register today: https://forms.gle/ug5R9KMKs1dXu28bA

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Conference / Symposium Tue, 09 Mar 2021 13:06:47 -0500 2021-03-26T09:00:00-04:00 2021-03-26T10:00:00-04:00 Off Campus Location Michigan India Conference Conference / Symposium Michigan India Conference
5th Annual RNA Symposium, "Processing RNA" (March 26, 2021 11:00am) https://events.umich.edu/event/80161 80161-20572610@events.umich.edu Event Begins: Friday, March 26, 2021 11:00am
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

FOR MORE DETAILS & ABSTRACTS VISIT: https://rna.umich.edu/2021-symposium/

Thursday, March 25, 2021
11:00 / Welcome
11:05 / KEYNOTE 1: Tracy Johnson, UCLA, “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression”
12:00 / Short break
12:10 / KEYNOTE 2: Kevin Weeks, UNC, “Structure-Based Discovery of New Functions in Large RNAs”
1:05 / Data Blitz: Cathy Smith, Daniel Peltier, Yan Zhang
1:35 / KEYNOTE 3: Feng Zhang, MIT, “Exploration of Biological Diversity to Discover Novel Molecular Technologies”
2:30 / Close Day 1

Friday, March 26, 2021
11:00 / Welcome
11:05 / KEYNOTE 4: Brenda Bass, University of Utah, “Distinguishing self and non-self dsRNA in vertebrates and invertebrates”
12:00 / Short break
12:10 / KEYNOTE 5: Christopher Lima, Sloan-Kettering Institute, “Mechanisms that target RNA for destruction”
1:05 / Data Blitz: Meredith Purchal, Adrien Chauvier, Shannon Wright
1:35 / Panel discussion with keynote speakers
2:30 / Close Day 2

Liveblogging by MiSciWriters! https://misciwriters.com/

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Lecture / Discussion Tue, 23 Mar 2021 15:03:26 -0400 2021-03-26T11:00:00-04:00 2021-03-26T14:30:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion 5th Annual RNA Symposium
CCMB / DCMB Weekly Seminar (March 31, 2021 4:00pm) https://events.umich.edu/event/83395 83395-21369780@events.umich.edu Event Begins: Wednesday, March 31, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Large, deeply phenotyped cohorts are reshaping the world of environmental epidemiology. Two such “big data” resources that are reshaping how we understand environmental health are electronic health records and human cohorts with genome-wide molecular phenotyping. Each provides a unique perspective that is moving the field closer towards “personalized” insights into environmental health risks. Here I will talk about a series of studies which utilize electronic health records and molecularly phenotyped cohorts to investigate vulnerable populations, gene-environment interactions, and epigenetic biomarkers of environmental sensitivity. Together these studies are helping us to understand environmental health risks in a new light.

Short bio:

Dr. Cavin Ward-Caviness is a Principal Investigator in the Public Health and Integrated Toxicology Division of the US Environmental Protection Agency. With a background in computational biology and environmental epidemiology, Dr. Ward-Caviness seeks to understand the environmental factors which influence health in vulnerable populations and the molecular mechanisms that influence environmental health risks. The Ward-Caviness lab uses a variety of “big data” approaches, and Dr. Ward-Caviness is the PI of the EPA CARES research resource, which allows researchers to study environmental health effects in vulnerable patient populations, e.g. individuals with heart failure, using large electronic health record databases. Dr. Ward-Caviness is also interested in how epigenetics and metabolomics can serve as an early indicator of adverse health effects from chemical and social environmental exposures and in particular how molecular biomarkers can give us insight into how the environment may accelerate the aging process and thus contribute to chronic disease. By integrating molecular and clinical data, Dr. Ward-Caviness seeks to understand environmental health as a way to advance personalized medicine and reduce health disparities.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 29 Mar 2021 15:15:11 -0400 2021-03-31T16:00:00-04:00 2021-03-31T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
COVID-19: Reflections and vision for the future (March 31, 2021 5:30pm) https://events.umich.edu/event/82941 82941-21227210@events.umich.edu Event Begins: Wednesday, March 31, 2021 5:30pm
Location: Off Campus Location
Organized By: Trotter Multicultural Center

This March marks the one year after the pandemic.

Join the Trotter Distinguished Leadership Series as we host social demographer, professor of Public Policy & Health Management and Policy, and Associate Dean for Academic Affairs, Dr. Paula Lantz for COVID-19: Reflections and vision for the future. Award-winning science journalist and author, Nicholas St. Fleur, will be moderating and guiding us through a discussion that reflects on the impacts of the pandemic on local community health and policy, and explores what comes next.

Trotter Multicultural Center looks forward to seeing you on March 31st from 5:30-7 PM. Register at: myumi.ch/9obEl

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Lecture / Discussion Tue, 23 Mar 2021 14:38:11 -0400 2021-03-31T17:30:00-04:00 2021-03-31T19:00:00-04:00 Off Campus Location Trotter Multicultural Center Lecture / Discussion Image of event flyer
DCM&B Tools and Technology Seminar (April 1, 2021 12:00pm) https://events.umich.edu/event/79922 79922-20515555@events.umich.edu Event Begins: Thursday, April 1, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

Many protein function databases are built on automated or semi-automated curations and can contain various annotation errors. The correction of such misannotations is critical to improving the accuracy and reliability of the databases. We proposed a new approach to detect potentially incorrect Gene Ontology (GO) annotations by comparing the ratio of annotation rates (RAR) for the same GO term across different taxonomic groups, where those with a relatively low RAR usually correspond to incorrect annotations. As an illustration, we applied the approach to 20 commonly studied species in two recent UniProt-GOA releases and identified 250 potential misannotations in the 2018-11-6 release, where only 25% of them were corrected in the 2019-6-3 release. Importantly, 56% of the misannotations are “Inferred from Biological aspect of Ancestor (IBA)”, i.e. reviewed computational annotations based on phylogenetic analysis. This is in contrast to previous observations that attributed misannotations mainly to “Inferred from Sequence or structural Similarity (ISS)”, probably reflecting an error source shift due to the new developments of function annotation databases. The results demonstrated a simple but efficient misannotation detection approach that is useful for developing taxonomic constraints in large-scale comparative protein function studies.

Tool Link: https://zhanglab.ccmb.med.umich.edu/RAR

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:17:31 -0500 2021-04-01T12:00:00-04:00 2021-04-01T13:00:00-04:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
BME 500 Seminar: Tim Downing (April 1, 2021 4:00pm) https://events.umich.edu/event/81392 81392-20889822@events.umich.edu Event Begins: Thursday, April 1, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

https://openbme.org/

ZOOM LINK TO REGISTER: https://cwru.zoom.us/webinar/register/WN_iY_PMZevQwWRYkMyK7ifzA

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Lecture / Discussion Fri, 26 Mar 2021 14:01:59 -0400 2021-04-01T16:00:00-04:00 2021-04-01T17:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
BME Seminar: Synthetic Genome Engineering for Cell and Tissue Engineering (April 1, 2021 4:00pm) https://events.umich.edu/event/80692 80692-20783435@events.umich.edu Event Begins: Thursday, April 1, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Title: Synthetic Genome Regulation for Cell and Tissue Engineering

Abstract: Molecular heterogeneity is emerging as a critical feature of multicellular life. While single-cell analyses have revealed the existence of cell-to-cell variation in the levels and activities of the molecules responsible for gene regulation, the source of such variation is still poorly understood. The Downing Lab studies how genome replication contributes to epigenetic heterogeneity across stem cell populations. We recently developed a new sequencing method (Repli-Bisulfite Sequencing) that enables analysis of DNA methylation within newly replicated strands of DNA over time. Using this method, we discovered that much of the methylation heterogeneity observed within human embryonic stem cells (hESCs) is temporal in nature and associated with DNA replication. Here, we employ bioinformatic analyses to explore how properties of post-replication DNA methylation dynamics relate to well-established features of the genome and the broader chromatin landscape. Our findings reveal that unique patterns of methylome replication associate with distal regulatory regions throughout the genome, enrich for cytosine residues dynamically methylated across cell types, and coincide with the location of stem cell-specific transcription factor binding and chromatin architectures. We also find correlations between sub-cell cycle kinetics in DNA methylation and the divergence of bulk methylation patterns observed during multiple cell generations and natural aging. Taken together, our studies suggest that (epi)genome replication may act as an important source of (temporal) regulatory variation in hESCs while, simultaneously, conferring susceptibility to epigenetic drift throughout the human lifespan. Our lab is also interested in understanding how the chemical and biophysical microenvironment influences adult cell behavior and phenotype through epigenetic gene regulatory mechanisms. We hope to use this information in the design of next-generation biomaterials. The second part of this presentation will describe how focal adhesions and cell-mediated forces contribute to inefficiencies observed during the acquisition of stemness from somatic cell states.



Biography: Tim Downing has been on the faculty at UC Irvine since 2016 and holds a primary appointment in the Department of Biomedical Engineering. He also holds a courtesy appointment in the Department of Microbiology & Molecular Genetics. Tim received his B.S. in Chemical Engineering in 2008 from Northwestern University and Ph.D. in Bioengineering from UC Berkeley in 2013 under the mentorship of Dr. Song Li. As a Ford Foundation and UNCF/Merck Fellow, Tim completed his postdoctoral training in stem cell epigenomics with Dr. Alexander Meissner at Harvard University and the Broad Institute (Cambridge, Massachusetts). The Downing Lab focuses on understanding gene regulation during tissue development, regeneration, and disease progression. Building on this information, the lab also aims to develop molecular tools and biomaterials to synthetically regulate the epigenome for better control over cell fate and behavior. Tim is a 2019 NIH (DP2) New Innovator Award recipient and a 2020 recipient of the “Rising Star” Award from the Cellular and Molecular Bioengineering (CMBE) Special Interest Group within the Biomedical Engineering Society (BMES).

Zoom Registration Link: https://cwru.zoom.us/webinar/register/WN_iY_PMZevQwWRYkMyK7ifzA

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Workshop / Seminar Thu, 25 Mar 2021 13:09:17 -0400 2021-04-01T16:00:00-04:00 2021-04-01T17:00:00-04:00 Off Campus Location Biomedical Engineering Workshop / Seminar Dr. Timothy L. Downing, UC Irvine
Health Professions Education (HPE) Day 2021 Virtual Event (April 6, 2021 8:00am) https://events.umich.edu/event/79926 79926-20515558@events.umich.edu Event Begins: Tuesday, April 6, 2021 8:00am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Dr. Umland is Co-Director and Associate Provost of Interprofessional Practice and Education at Jefferson Center for Interprofessional Practice and Education (JCIPE).
There will be a poster session after the plenary/Q&A. Check the website for more information about abstract/poster submission.
HPE Day is an opportunity to share and disseminate scholarly efforts, completed or in progress, and to spark the dialogue required to synergize our work. This event will bring together educational scholars, practitioners, researchers and students to share best practices and explore opportunities for collaboration and innovation. The day’s highlights will include sharing of our initial efforts in interprofessional education and collaborative care and discussion of opportunities for the growth of collaboration across the health science schools and the broader campus community.

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Conference / Symposium Fri, 11 Dec 2020 10:06:56 -0500 2021-04-06T08:00:00-04:00 2021-04-06T13:00:00-04:00 Off Campus Location Department of Learning Health Sciences Conference / Symposium Health Professions Education Day 2021 Virtual Event
CCMB / DCMB Weekly Seminar Series (April 7, 2021 4:00pm) https://events.umich.edu/event/83241 83241-21320453@events.umich.edu Event Begins: Wednesday, April 7, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: More than 3,000 new Marine recruits were studied prospectively during their initial Marine-mandated two-week quarantine and their subsequent basic training at Parris Island. The COVID Health Action Response for Marines (CHARM) studied completed 20,000 study visits and obtained more than 70,000 biosamples including pre- to post- SARS-CoV-2 infections in more than 1000 recruits. Serological, transcriptomic, and epigenetic analyses identify the response signature to SARS-CoV-2 infection in these largely asymptomatic young adults. Phylogenetic analysis and modeling provide insight into epidemiology and guidance for public health measures.

* * *

Specialty: Neurology

Research Topics: Addiction, Apoptosis/Cell Death, Basal Ganglia, Bioinformatics, Brain, Cellular Immunity, Cerebral Cortex, Mathematical and Computational Biology, Multiple Sclerosis, Neuro-degeneration/protection, Receptors, Reproductive Biology, Signal Transduction, Theoretical Biology, Vaccine Development, Viruses and Virology

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 23 Mar 2021 11:23:58 -0400 2021-04-07T16:00:00-04:00 2021-04-07T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
What’s Next? How the COVID-19 Vaccines Can Change Our Lives (April 8, 2021 9:30am) https://events.umich.edu/event/83403 83403-21369801@events.umich.edu Event Begins: Thursday, April 8, 2021 9:30am
Location: Off Campus Location
Organized By: School of Public Health

Join infectious disease experts from the University of Michigan School of Public Health and Michigan Medicine for a panel discussion on the COVID-19 vaccines and what we can expect in the weeks and months ahead. The panel will include:

Dr. Arnold Monto, Professor of Epidemiology, University of Michigan School of Public Health
Dr. Sandro Cinti, Clinical Professor of Infectious Diseases, Michigan Medicine and Ann Arbor VA Health System
Dr. Laraine Washer, Clinical Associate Professor of Infectious Diseases, Michigan Medicine
Moderated by: Dr. Emily Martin, Associate Professor of Epidemiology, University of Michigan School of Public Health

* This event is free and open to the public but registration is required. https://sph.umich.edu/events/event.php?ID=8842

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Livestream / Virtual Mon, 29 Mar 2021 17:12:47 -0400 2021-04-08T09:30:00-04:00 2021-04-08T10:30:00-04:00 Off Campus Location School of Public Health Livestream / Virtual Event promotion graphic
What’s Next? How the COVID-19 Vaccines Can Change Our Lives (April 8, 2021 9:30am) https://events.umich.edu/event/83403 83403-21369802@events.umich.edu Event Begins: Thursday, April 8, 2021 9:30am
Location: Off Campus Location
Organized By: School of Public Health

Join infectious disease experts from the University of Michigan School of Public Health and Michigan Medicine for a panel discussion on the COVID-19 vaccines and what we can expect in the weeks and months ahead. The panel will include:

Dr. Arnold Monto, Professor of Epidemiology, University of Michigan School of Public Health
Dr. Sandro Cinti, Clinical Professor of Infectious Diseases, Michigan Medicine and Ann Arbor VA Health System
Dr. Laraine Washer, Clinical Associate Professor of Infectious Diseases, Michigan Medicine
Moderated by: Dr. Emily Martin, Associate Professor of Epidemiology, University of Michigan School of Public Health

* This event is free and open to the public but registration is required. https://sph.umich.edu/events/event.php?ID=8842

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Livestream / Virtual Mon, 29 Mar 2021 17:12:47 -0400 2021-04-08T09:30:00-04:00 2021-04-08T10:30:00-04:00 Off Campus Location School of Public Health Livestream / Virtual Event promotion graphic
DCM&B Tools and Technology Seminar (April 8, 2021 12:00pm) https://events.umich.edu/event/79923 79923-20515556@events.umich.edu Event Begins: Thursday, April 8, 2021 12:00pm
Location: Off Campus Location
Organized By: DCMB Tools and Technology Seminar

URL for remote viewing: https://umich-health.zoom.us/j/94886745590?pwd=LzhLU243K2ZhbXNzU1BJRHQ5V25BZz09

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Livestream / Virtual Fri, 11 Dec 2020 08:19:03 -0500 2021-04-08T12:00:00-04:00 2021-04-08T13:00:00-04:00 Off Campus Location DCMB Tools and Technology Seminar Livestream / Virtual
BME 500 Seminar: James Collins (April 8, 2021 4:00pm) https://events.umich.edu/event/81393 81393-20889823@events.umich.edu Event Begins: Thursday, April 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

James Collins, Ph.D.
Massachusetts Institute of Technology

https://openbme.org/

ZOOM LINK TO REGISTER: https://cwru.zoom.us/webinar/register/WN_MSUiecgNTLyXR5bM8HSnR

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Lecture / Discussion Fri, 02 Apr 2021 15:01:39 -0400 2021-04-08T16:00:00-04:00 2021-04-08T17:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
Alum Connections: Dr. Gina Fundaro (April 9, 2021 12:30pm) https://events.umich.edu/event/83335 83335-21344238@events.umich.edu Event Begins: Friday, April 9, 2021 12:30pm
Location: Off Campus Location
Organized By: LSA Opportunity Hub

Alum Connection: Women’s Health leader & Entrepreneur, Dr. Gina Fundaro

In January 2020, Dr. Gina Fundaro found herself at a crossroads. She was a successful breast imaging radiologist with Henry Ford Health System, while her children were also succeeding athletically in their early teenage years. After a twenty-year career impacting patients’ lives, Gina made the decision to stop practicing medicine and open three Goldfish Swim Schools in Virginia. Just over a year later, Gina is back working with patients part-time. A proud U-M Dearborn graduate, Gina attributes her liberal arts education for giving her both a desire to serve others through her medical vocation and the agility to pivot into entrepreneurial pursuits. Join Gina for a conversation about exploring a medical career in service to others--and having the courage to make life changes as an established adult and professional.

About Dr. Gina Fundaro:
A lifelong native of Michigan, Dr. Gina Fundaro spent the majority of her career at Henry Ford Health System. She was also the site director of the Henry Ford Fairlane Breast Center. Prior to this, she worked at the Alexander Walt Comprehensive Breast Center of the Karmanos Cancer Institute from 2005 to 2007. She specializes in breast imaging and breast interventional procedures. She joined a private group, Regional Medical Imaging in January 2021.

Her passion for women’s healthcare arose while in college following her grandmother’s death from preventable breast cancer. It highlighted the need to catch breast tumors early, spurring her to enter radiology and help women fight the disease.

Being a physician, it was important to Gina that her kids learned how to swim. This passion also drove Gina to learn how to swim at age 39, and in 2012, she completed an Ironman Triathlon. Two years later, Gina and her husband opened their first of three Goldfish Swim Schools in Northern, VA.

You should attend this session if you are:
A UM Literature, Science, and the Arts undergraduate student with interests in working in the field of healthcare
Interested in medical school and/or pursuing a career in medicine, specifically radiology
Hoping to learn from an alum about navigating life in medical school, as well as finding work-life balance as a practicing physician

What you’ll gain from attending this session:
Get insights from an experienced physician who currently sits on the Mott Hospital Council and Women's Health Leadership Council at Michigan Medicine
Learn about the career possibilities within medicine prior to applying to medical school.
Gain critical advice about pursuing both a lifelong career but also shorter professional pursuits

RSVP now to be part of the conversation. The link to join this Alum Connection will be emailed to you after you RSVP.

Posting Disclaimer:
RSVP now to reserve your spot. By signing up, you will receive an email with details on how to join this virtual workshop the morning of the session.

The LSA Opportunity Hub aims to deliver inclusive and accessible experiences and welcomes all LSA students to participate. If you require accommodations to participate in this event please contact the Hub at lsa-opphub@umich.edu so we can make arrangements. If you have any concerns or questions, please reach out to us at lsa-opphub@umich.edu.

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Livestream / Virtual Fri, 26 Mar 2021 10:25:45 -0400 2021-04-09T12:30:00-04:00 2021-04-09T13:30:00-04:00 Off Campus Location LSA Opportunity Hub Livestream / Virtual Dr. Gina Fundaro Photo
RC Intros: Interested in learning more about the Residential College? (April 12, 2021 5:00pm) https://events.umich.edu/event/81794 81794-20959285@events.umich.edu Event Begins: Monday, April 12, 2021 5:00pm
Location: Off Campus Location
Organized By: Residential College

RC Intros: Interested in learning more about the Residential College?

Wondering what happens after the RC? Meet RC alumni and learn about their post-grad experiences!

Monday, April 12, 5-6pm
Register at myumi.ch/E3WA5

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Reception / Open House Fri, 05 Feb 2021 14:43:56 -0500 2021-04-12T17:00:00-04:00 2021-04-12T18:00:00-04:00 Off Campus Location Residential College Reception / Open House RC Intros flier
Can Education Innovation at Michigan Medicine Benefit from Being More Cohesive? (April 14, 2021 12:00pm) https://events.umich.edu/event/83220 83220-21314487@events.umich.edu Event Begins: Wednesday, April 14, 2021 12:00pm
Location: Off Campus Location
Organized By: RISE (Research. Innovation. Scholarship. Education.)

RISE invites you attend the Virtual Talking Circle (VTC) to contribute your input in co-creating a cohesive pathway for education innovation across health science education at Michigan Medicine.  We invite you to attend and provide your input into this conversation.

Please invite your colleagues who may also be interested. See you then!

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Workshop / Seminar Wed, 24 Mar 2021 14:31:47 -0400 2021-04-14T12:00:00-04:00 2021-04-14T13:00:00-04:00 Off Campus Location RISE (Research. Innovation. Scholarship. Education.) Workshop / Seminar RISE Virtual Talking Circle
CCMB / DCMB Weekly Seminar (April 14, 2021 4:00pm) https://events.umich.edu/event/83595 83595-21436485@events.umich.edu Event Begins: Wednesday, April 14, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
My lab's research involves the development and application of systems biology approaches—combining computation, machine learning, quantitative modeling, and experiments—to study the immune system in health and disease. Recent technological and computational advances allow comprehensive interrogation of multiple modalities (e.g., proteins, mRNAs, immune receptor sequences) in single cell resolution in the human population. Here I will highlight our work in the analysis human and single cell variations along the axes of early immune development, vaccination, and COVID-19. If time permits, I will also discuss the integration of tissue imaging, machine learning, and multiscale dynamical modeling of immune cell interactions to investigate the homeostatic regulation of autoreactive T cells.

* * *

Biography: Dr. Tsang is a senior investigator in the NIH Intramural Research Program and leads a laboratory focusing on systems and quantitative immunology at the National Institute of Allergy and Infectious Diseases (NIAID). He also co-directs the Trans-NIH Center for Human Immunology (CHI) and leads its research program in systems human immunology. Dr. Tsang trained in computer engineering and computer science at the University of Waterloo and received his Ph.D. in biophysics from Harvard University. Dr. Tsang has worked as a software engineer and pursued systems biology research in both academia and industry including Rosetta Inpharmatics, Caprion Proteomics, MIT, and Merck Research Laboratories. Dr. Tsang has won several awards for his research, including NIAID Merit Awards for the development of a data reuse and crowdsourcing platform OMiCC and for leading a system biology study of human immune variability and influenza vaccination, which was selected as a top NIAID Research Advances of 2014. He currently serves as the founding chief editor of systems immunology for Frontiers in Immunology. He has served as a scientific advisor for a number of programs and organizations including ImmPort (the clinical and molecular data repository for NIAID), the Committee on Precision Medicine for the World Allergy Organization, the NIAID Modeling Immunity for Biodefense Program, the Allen Institute, the Immuno-Epidemiology Program at the National Cancer Institute, and the Human Vaccines Project.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 07 Apr 2021 08:59:05 -0400 2021-04-14T16:00:00-04:00 2021-04-14T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
BME 500 Seminar: Kelly J. Cross (April 15, 2021 4:00pm) https://events.umich.edu/event/81394 81394-20889824@events.umich.edu Event Begins: Thursday, April 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for a virtual seminar series on topics related to race and science, technology, engineering and math (STEM) education. https://happenings.wustl.edu/event/an_honest_conversation_about_inequity_in_engineering#.YG9vT-hKhPY

Details:
DATE: Thursday, April 15, 2021
TIME: 4:00-5:00 PM
ZOOM LINK TO REGISTER: https://wustl.zoom.us/webinar/register/WN_NvH4qVTSRx2uSXbdW-eXNA

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Lecture / Discussion Wed, 14 Apr 2021 14:13:34 -0400 2021-04-15T16:00:00-04:00 2021-04-15T17:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
The University of Michigan Medical School Program on Health, Spirituality and Religion presents "An Evening with Health, Spirituality and Religion: A Multi-disciplinary Conversation on a Challenging End-of-Life Clinical Scenario (April 15, 2021 7:00pm) https://events.umich.edu/event/83261 83261-21328371@events.umich.edu Event Begins: Thursday, April 15, 2021 7:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

Join us for a discussion with a panel of experts from a variety of disciplines as we unpack a recent challenging case at our own institution. Our panel will navigate the complexity of caring for an elderly patient presenting after suicide attempt who requested DNAR status.

Kunal Bailoor, MD, House Officer, Internal Medicine, Ethics

Lori-Jean Brazier, M.Div., CPE, Spiritual Care

Sara Didoszak, BSN, RN, Clinical Nursing Supervisor, CCMU

Thomas Valley, MD, MSc, Assistant Professor of Internal Medicine, Division of Pulmonary and Critical Care

Scott Winder, MD, Associate Professor of Psychiatry and Associate Professor of Surgery

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Workshop / Seminar Wed, 24 Mar 2021 07:13:57 -0400 2021-04-15T19:00:00-04:00 2021-04-15T20:00:00-04:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar Health, Spirituality & Religion Program
BME Master's Defense: Fatimah Alkaabi (April 16, 2021 12:00pm) https://events.umich.edu/event/83558 83558-21424731@events.umich.edu Event Begins: Friday, April 16, 2021 12:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

The central auditory system consists of the brain nuclei that transmit peripheral auditory nerve input to the auditory cortex for hearing perception. Damage to the auditory end organ, the cochlea, can result in hearing loss that drives the central auditory system to disarray causing disorders such as hyperacusis and tinnitus. These disorders can negatively affect patients’ quality of life. Tinnitus sufferers generally describe their tinnitus as a narrowband of sound that occurs in quiet, while hyperacusis sufferers express an exaggerated perception of sound level or intensity. These two disorders are often grouped together because tinnitus sufferers tend to report symptoms of hyperacusis and vice versa. However, hyperacusis and tinnitus do not always co-occur, suggesting that they have different neural origins. To study these conditions, researchers have induced cochlear damage in animal models, followed by behavioral and electrophysiological assessments. However, no study has adequately distinguished hyperacusis from tinnitus in individual animals. In this thesis, I detail the development of a novel hyperacusis and tinnitus assessment paradigm for individual animals using the pinna reflex combined with auditory brainstem responses (ABR). In the first chapter, I detail several enhancements to a computer system that ensures accurate sound presentation concurrently with capture of pinna reflex video data, as well as streamlines the subsequent data analysis. In the second chapter, the ABR, an evoked potential reflecting the summed electrical activity of cells in the auditory brainstem pathway, was assessed. Several studies suggest that ABR-wave characteristics might provide evidence of hyperacusis. ABRs were evoked using conventional and novel sound stimuli. They were then examined to look for possible indications of hyperacusis in noise overexposed guinea pigs. The present findings are discussed with several suggestions for future hyperacusis assessments.



Date: Friday, April 16, 2021

Time: 12:00 PM

Zoom: https://umich.zoom.us/j/91698183229

Chair: Dr. Susan Shore

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Lecture / Discussion Mon, 05 Apr 2021 23:04:39 -0400 2021-04-16T12:00:00-04:00 2021-04-16T13:00:00-04:00 Off Campus Location Biomedical Engineering Lecture / Discussion BME Logo
"A Relationship Based Model of Care: Combining a great compassion and a great commission ministry for better health outcomes" (April 19, 2021 12:00pm) https://events.umich.edu/event/83262 83262-21328372@events.umich.edu Event Begins: Monday, April 19, 2021 12:00pm
Location: Off Campus Location
Organized By: The University of Michigan Medical School Program on Health, Spirituality and Religion

The Woll Family Speaker Series on Health, Spirituality and Religion presents Sherie Garrison, RN and Brad Garrison, BS, RPH, M.Div.

The launch of the Luke Project 52 Clinic of Flint will combine a Great Compassion ministry to provide free prenatal care to the uninsured or under-insured in an effort to address the high infant mortality rate there with a Great Commission ministry to provide a mobile asset to local congregations to help them connect with and begin to serve again the communities that they are in. Connecting our Moms with the community support system of a church will enhance their ability to get the care they need.

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Workshop / Seminar Wed, 24 Mar 2021 07:22:00 -0400 2021-04-19T12:00:00-04:00 2021-04-19T13:00:00-04:00 Off Campus Location The University of Michigan Medical School Program on Health, Spirituality and Religion Workshop / Seminar Health, Spirituality & Religion Program
The 20th Annual Horace W. Davenport Lecture in Medical Humanities (April 19, 2021 3:00pm) https://events.umich.edu/event/83733 83733-21483492@events.umich.edu Event Begins: Monday, April 19, 2021 3:00pm
Location: Off Campus Location
Organized By: Center for the History of Medicine

The Center for the History of Medicine and the Department of English Language and Literature are pleased to announce the 20th Annual Horace W. Davenport Lecture in the Medical Humanities.

This year's lecture will feature Professor Deborah Blum, Director of the Knight Science Journalism Program at the Massachusetts Institute of Technology. Blum is a Pulitzer Prize winning science journalist, columnist and author of six books, most recently, The Poison Squad, a 2018 New York Times Notable Book, and the subject of a 2020 PBS documentary.

Blum will deliver her lecture, "Science Journalism Under the Microscope: From COVID to Climate Change," where she will explores the sometimes mysterious (to others) ways that journalists pick stories, balance evidence, find sources, and spin their tales, using examples from some of the most important stories of the last decade to illustrate good choices and bad, mistakes and successes, to make some essential and insightful points about the profession.

Blum won the Pulitzer in 1992 for a series on primate research that became her first book, The Monkey Wars. She has since focused on key moments in the history of science with books including Love at Goon Park (2002), Ghost Hunters (2006), the New York Times bestseller, The Poisoner’s Handbook (2010). A co-editor of A Field Guide for Science Writers (2006), she is now under contract with Oxford University Press as a co-editor of a forthcoming guide to science journalism. She has worked as a science columnist for The New York Times, a blogger for Wired, and has written for other publications ranging from The Wall Street Journal to Mother Jones. She was the Helen Firstbrook Franklin professor of journalism at the University of Wisconsin-Madison for 15 years before being selected as the fourth director of the Knight Science Journalism Program in 2015. Shortly later, she launched the online science magazine, Undark, which now numbers a readership in the millions and has won numerous national awards, including the George K. Polk Award.

Blum is a former president of the National Association of Science Writers, was a member of the governing board of the World Federation of Science Writers, and currently serves on the board of the Council for the Advancement of Science Writing, and on advisory boards of Chemical & Engineering News, The Scientist and the MIT Museum. She is a fellow of the American Association for the Advancement of Science (AAAS) and a lifetime associate of the National Academy of Sciences (NAS) in recognition of her work in science communication.

Please join us for this engaging presentation from one of the nation’s premiere science journalists!

Monday, April 19, 2021
3:00 - 4:00 pm

Zoom link: https://umich.zoom.us/s/95201112797

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Livestream / Virtual Tue, 13 Apr 2021 09:00:10 -0400 2021-04-19T15:00:00-04:00 2021-04-19T16:00:00-04:00 Off Campus Location Center for the History of Medicine Livestream / Virtual Science Journalism Under the Microscope: From Covid to Climate Control
RNA Seminar featuring: Jailson (Jay) Brito Querido, Ph.D. MRC Laboratory of Molecular Biology, Cambridge, UK (April 19, 2021 4:00pm) https://events.umich.edu/event/81408 81408-20893767@events.umich.edu Event Begins: Monday, April 19, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_78YYOhIhTbOBy2_JSdM7Wg

ABSTRACT: A key step in translational initiation is the recruitment of the 43S pre-initiation complex (43S PIC) by the cap-binding complex (eIF4F) at the 5´ end of mRNA. Eukaryotic initiation factors eIF1, eIF1A, eIF3, eIF5, and the ternary complex (TC) of eIF2–GTP–tRNAiMet bind to the 40S ribosomal subunit to form the 43S PIC. Once assembled, the 43S PIC is recruited to the cap-binding complex eIF4F at the 5´end of mRNA to form a 48S initiation complex (48S). The 48S then scans along the mRNA to locate a start codon. To understand the mechanisms involved, we determined the structure of a reconstituted human 48S using cryo-electron microscopy. The structure reveals insights into early events of translation initiation complex assembly. It reveals how eIF4F interacts with subunits of the eIF3 structural core near the mRNA exit channel in the 43S. The location of eIF4F is consistent with a slotting model of mRNA recruitment and suggests a “blind-region” that would preclude recognition of start sites upstream of the location of the P site at the point of recruitment.

KEYWORDS: mRNA, ribosome, eIF4F, eIF4A, translation

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Lecture / Discussion Tue, 13 Apr 2021 12:58:40 -0400 2021-04-19T16:00:00-04:00 2021-04-19T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Jailson (Jay) Brito Querido, Ph.D.
Links Between Culture and Sanitation (April 20, 2021 2:00pm) https://events.umich.edu/event/83816 83816-21540180@events.umich.edu Event Begins: Tuesday, April 20, 2021 2:00pm
Location:
Organized By: Project RISHI

Dr. Balmurli Natrajan, Professor of Anthropology at William Paterson University will speak on the social practices in communities where open defecation is prevalent, toilet use, and sanitation practices in India. The discussion will center around the link between culture and accepting modern adaptations in rural communities. RSVP Here: https://docs.google.com/forms/d/e/1FAIpQLSdaJwRFl1WH56j3j604SnuPiLF5vRvgiAHais0Hse4ISjAATA/viewform

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Conference / Symposium Tue, 20 Apr 2021 14:07:20 -0400 2021-04-20T14:00:00-04:00 2021-04-20T15:00:00-04:00 Project RISHI Conference / Symposium Dr. Balmurli Natrajan, Professor of Anthropology at William Paterson University
Bioethics Discussion: Abdication (April 20, 2021 7:00pm) https://events.umich.edu/event/58841 58841-14563735@events.umich.edu Event Begins: Tuesday, April 20, 2021 7:00pm
Location: Lurie Biomedical Engineering
Organized By: The Bioethics Discussion Group

A discussion on our renunciation.

Join us at: https://umich.zoom.us/j/99926126455

A few readings to consider:
––The Idea of Legitimate Authority in the Practice of Medicine
––Decentralization of health care systems and health outcomes: Evidence from a natural experiment
––Vox Populi or Abdication of Responsibility?: The Influence of the Irish Citizens’ Assembly on the Public Discourse Regarding Abortion, 2016-2019
––Lifeboat Ethics: The Case Against Helping the Poor
For more information and/or to receive a copy of the readings visit http://belmont.bme.umich.edu/bioethics-discussion-group/discussions/060-abdication/.

––
Before you give up, consider the blog: https://belmont.bme.umich.edu/incidental-art/

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Lecture / Discussion Fri, 08 Jan 2021 09:38:57 -0500 2021-04-20T19:00:00-04:00 2021-04-20T20:30:00-04:00 Lurie Biomedical Engineering The Bioethics Discussion Group Lecture / Discussion Abdication
Special Joint Seminar between DCMB, Mathematics, MIDAS, and Smale Institute (April 22, 2021 1:00pm) https://events.umich.edu/event/83615 83615-21491327@events.umich.edu Event Begins: Thursday, April 22, 2021 1:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

The quest to understand consciousness, once the purview of philosophers and theologians, is now actively pursued by scientists of many stripes. This talk looks at consciousness from the perspective of theoretical computer science. It formalizes the Global Workspace Theory (GWT) originated by cognitive neuroscientist Bernard Baars and further developed by him, Stanislas Dehaene, and others. Our major contribution lies in the precise formal definition of a Conscious Turing Machine (CTM), also called a Conscious AI. We define the CTM in the spirit of Alan Turing’s simple yet powerful definition of a computer, the Turing Machine (TM). We are not looking for a complex model of the brain nor of cognition but for a simple model of (the admittedly complex concept of) consciousness. After formally defining CTM, we give a formal definition of consciousness in CTM. We then suggest why the CTM has the feeling of consciousness. The reasonableness of the definitions and explanations can be judged by how well they agree with commonly accepted intuitive concepts of human consciousness, the range of related concepts that the model explains easily and naturally, and the extent of its agreement with scientific evidence.

https://umich.zoom.us/j/95135773568

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Livestream / Virtual Wed, 14 Apr 2021 10:17:45 -0400 2021-04-22T13:00:00-04:00 2021-04-22T14:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Re-orienting Ancient Medicine Courses (April 22, 2021 4:00pm) https://events.umich.edu/event/83375 83375-21367803@events.umich.edu Event Begins: Thursday, April 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Middle East Studies

This pedagogy workshop is aimed at (past, current, and would-be) instructors of ancient medicine, science, and technology courses who would be keen to integrate material from the pre-modern Middle East. Popular and more academic narratives often equate ancient medicine with Greco-Roman medicine and frame its study as an originist history of a monolithic western medical tradition. When these narratives introduce content from the pre-modern Middle East, such as from Assyria or the medieval Islamicate world, they define the contribution of Middle Eastern knowledge-makers in terms of their anticipation or preservation of a western science.

This workshop will discuss ways of foregrounding the theories and actors of pre-modern Middle Eastern science, technology, and medicine without rendering them subservient to a hegemonic "western tradition". Moreover, we will review a range of primary and secondary source materials that we utilize in our own teaching of these subjects. Questions or concerns can be addressed to cwebster@ucdavis.edu. Co-sponsored by the Society for Ancient Medicine and the UC Davis Early Science Workshop.

Please register here:
https://umich.zoom.us/webinar/register/WN_M-fHevFTRIuOA7fS2Z4epQ

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Livestream / Virtual Mon, 29 Mar 2021 11:10:22 -0400 2021-04-22T16:00:00-04:00 2021-04-22T17:00:00-04:00 Off Campus Location Department of Middle East Studies Livestream / Virtual poster
Links Between Culture and Sanitation (April 22, 2021 5:00pm) https://events.umich.edu/event/83816 83816-21540179@events.umich.edu Event Begins: Thursday, April 22, 2021 5:00pm
Location: Off Campus Location
Organized By: Project RISHI

Dr. Balmurli Natrajan, Professor of Anthropology at William Paterson University will speak on the social practices in communities where open defecation is prevalent, toilet use, and sanitation practices in India. The discussion will center around the link between culture and accepting modern adaptations in rural communities. RSVP Here: https://docs.google.com/forms/d/e/1FAIpQLSdaJwRFl1WH56j3j604SnuPiLF5vRvgiAHais0Hse4ISjAATA/viewform

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Conference / Symposium Tue, 20 Apr 2021 14:07:20 -0400 2021-04-22T17:00:00-04:00 2021-04-22T18:00:00-04:00 Off Campus Location Project RISHI Conference / Symposium Dr. Balmurli Natrajan, Professor of Anthropology at William Paterson University
The Implications of COVID-19 for the Care of Our Athletes, Panel Discussion (April 23, 2021 10:30am) https://events.umich.edu/event/83762 83762-21493284@events.umich.edu Event Begins: Friday, April 23, 2021 10:30am
Location: Off Campus Location
Organized By: U-M Office of Research

Join the Exercise & Sport Science Initiative (ESSI) and Michigan Center for Human Athletic Medicine & Performance (MCHAMP) for a seminar discussing the implications of COVID-19 for the care of our athletes. Experts will discuss caring for athletes on the sideline and virtually in clinic; monitoring athletes' mental health and well-being during the pandemic; assessing the impact of altered conditioning, training and gameplay on injury risk and performance; advancing COVID-19 benchtop to sideline research; and applying lessons learned from the challenges of the last year to advance the care for athletes of all ages and levels of performance.

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Lecture / Discussion Wed, 14 Apr 2021 14:57:16 -0400 2021-04-23T10:30:00-04:00 2021-04-23T11:30:00-04:00 Off Campus Location U-M Office of Research Lecture / Discussion Elite baseball player with COVID-19 mask