Happening @ Michigan https://events.umich.edu/list/rss RSS Feed for Happening @ Michigan Events at the University of Michigan. HET Brown Bag Seminar | Neutrino Oscillations: Where we are, where we’re going (January 20, 2021 12:00pm) https://events.umich.edu/event/80667 80667-20769661@events.umich.edu Event Begins: Wednesday, January 20, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

In the last several decades, neutrino oscillations have gone from an experimental anomaly to robust evidence for beyond-the-Standard-Model physics. While much has been learned since the first experiments, several aspects of oscillations remain unknown, including the degree to which CP is violated in the lepton sector. In this talk, I will explore our current knowledge of neutrino oscillations, and discuss how the next generation of experiments can further enlighten us. These upcoming experiments have the ability to test “standard” and BSM neutrino oscillation hypotheses, as well as a multitude of non-neutrino BSM physics scenarios.

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Lecture / Discussion Tue, 12 Jan 2021 16:04:36 -0500 2021-01-20T12:00:00-05:00 2021-01-20T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Department Colloquium | Moiré Superlattices: A New Hubbard Model simulator? (January 20, 2021 4:00pm) https://events.umich.edu/event/80613 80613-20763720@events.umich.edu Event Begins: Wednesday, January 20, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Link: http://myumi.ch/GkgBm

The Hubbard model, first formulated by physicist John Hubbard in the 1960s, is a simple theoretical model of interacting quantum particles in a lattice. The model is thought to capture the essential physics of high-temperature superconductors, magnetic insulators, and other complex emergent quantum many-body ground states. Although the Hubbard model is greatly simplified as a representation of most real materials, it has nevertheless proved difficult to solve accurately except in the one-dimensional case. Physical realization of the Hubbard model in two or three dimensions, which can act as quantum simulators, therefore have a vital role to play in solving the strong-correlation puzzle. In this talk, I will discuss a potential experimental realization of the two-dimensional triangular lattice Hubbard model in angle-aligned heterobilayers of semiconducting transition metal dichalcogenides, which form moiré superlattices because of the difference in lattice constant between the two semiconductors.

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Workshop / Seminar Wed, 20 Jan 2021 18:15:27 -0500 2021-01-20T16:00:00-05:00 2021-01-20T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Physics potential of high energy muon collider (January 22, 2021 3:00pm) https://events.umich.edu/event/80527 80527-20736170@events.umich.edu Event Begins: Friday, January 22, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link : http://myumi.ch/O4P7E

Momentum has been accumulating to consider high energy muon collider as a future high energy collider possibility, especially on the US soil. Muon collider has unique physics cases, both as a Higgs factory as well as a high energy lepton collider. In this talk, I will review the overall physics pictures for muon colliders and discuss these unique physics cases. In particular, I will show a recent study where we rethink about WIMP DM and their testability at colliders. We show that through the new signature and channels proposed by us, we can draw some conclusive statements about WIMP DM, which can serve as a physics driver case for high energy muon colliders.

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Lecture / Discussion Fri, 15 Jan 2021 17:12:48 -0500 2021-01-22T15:00:00-05:00 2021-01-22T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | New Perspectives on Segmented Crystal Calorimeters for Future e+e- Higgs Factories (January 25, 2021 4:00pm) https://events.umich.edu/event/80560 80560-20740173@events.umich.edu Event Begins: Monday, January 25, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Crystal calorimeters have a long history of pushing the frontier on high-resolution electromagnetic (EM) calorimetry for photons and electrons and exploiting the technological advancements in the field can represent an excellent tool to tackle the challenge of precision physics at future e+e- Higgs factories.

I will discuss in this seminar major innovations in collider detector performance that can be achieved with crystal calorimetry when longitudinal segmentation and dual-readout capabilities are combined with a new high EM resolution approach to Particle Flow in multi-jet events, such as e+e+→HZ events in all-hadronic final-states at Higgs factories. In particular, I will discuss a new technique for pre-processing π0 momenta through combinatoric di-photon pairing in advance of applying jet algorithms which significantly reduces π0 photon splitting across jets in multi-jet events and lead to an improvement of the correct photon-to-jet assignment efficiency by a factor of about 3 when the EM resolution is improved from 15 to 3%/√E.

I will then present the design and optimization of a highly segmented crystal detector concept that achieves the required energy resolution of 3%/√E, and a time resolution better than 30 ps providing exceptional particle identification capabilities and discuss how the implementation of dual-readout on crystals permits to achieve a resolution better than 30%/√E for neutral hadrons. The cost-effective design presented demonstrates how the integration of crystal calorimetry into future Higgs factory collider detectors can open new perspectives by yielding the highest level of combined EM and neutral hadron resolution in the PFA paradigm.

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Workshop / Seminar Mon, 25 Jan 2021 18:15:31 -0500 2021-01-25T16:00:00-05:00 2021-01-25T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Department of Computational Medicine & Bioinformatics Seminar (January 27, 2021 4:00pm) https://events.umich.edu/event/80722 80722-20777538@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Massively parallel single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened the way to systematic tissue atlases in health and disease, but as the scale of data generation is growing, so is the need for computational pipelines for scaled analysis. We developed Cumulus, the first comprehensive cloud-based framework, to address the big data challenge arising from sc/snRNA-seq analysis. Cumulus combines the power of cloud computing with improvements in algorithm and implementation to achieve high scalability, low cost, user-friendliness and integrated support for a comprehensive set of features. We benchmark Cumulus on the Human Cell Atlas Census of Immune Cells dataset of bone marrow cells and show that it substantially improves efficiency over conventional frameworks, while maintaining or improving the quality of results, enabling large-scale studies.

In recent years, biologists have found that sc/snRNA-seq alone is not enough to reveal the full picture of how cells function and coordinate with each other in a complex tissue. They begin to couple sc/snRNA-seq with other common data modalities, such as single-cell ATAC-seq (scATAC-seq), single-cell Immune Repertoire sequencing (scIR-seq), spatial transcriptomics and mass cytometry. This data coupling is called single-cell multimodal omics. As it is becoming a new common practice, new analysis needs emerge along with two major computational challenges: big data challenge and integration challenge. The big data challenge requires us to develop scalable computational infrastructure and algorithms to deal with the ever-growing large datasets produced from the community. The integration challenge requires us to design new algorithms to enable holistic integration of heterogeneous data from different modalities. In the last part of my talk, I will discuss my team’s efforts and plans to develop Cumulus as an integrated data analysis framework for scaled single-cell multimodal omics.

Single-cell multimodal omics has the potential to provide a more comprehensive characterization of complex multicellular systems than the sum of its parts. As the datasets produced from the community keep growing substantially, the enhanced Cumulus will continue playing an important role in the effort to build atlases of complex tissues and organs at higher cellular resolution, and in leveraging them to understand the human body in health and disease.

Short bio: Dr. Bo Li is an assistant professor of medicine at Harvard Medical School, the director of Bioinformatics and Computational Biology at Center for Immunology Inflammatory Diseases, Massachusetts General Hospital, and an associate member of the Broad Institute of MIT and Harvard. His research focuses on large-scale single-cell and single-nucleus genomics data analysis. He received his Ph.D. in computer science from UW-Madison and completed two postdoctoral trainings with Dr. Lior Pachter at UC Berkeley and Dr. Aviv Regev at Broad Institute. He is best known for developing RSEM, an impactful RNA-seq transcript quantification software. RSEM is cited 9,384 times (Google Scholar) and adopted by several big consortia such as TCGA, ENCODE, GTEx and TOPMed.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 13 Jan 2021 14:32:34 -0500 2021-01-27T16:00:00-05:00 2021-01-27T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Bo Li, PhD (Assistant Professor at Harvard Medical School in Boston, MA)
Science Success Series | Growth and Grit: Developing a Mindset for Success (January 27, 2021 4:00pm) https://events.umich.edu/event/80591 80591-20759748@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: Science Learning Center

What if your ability to succeed in your classes was determined in part before you even stepped into the classroom? What is the one quality you need to overcome adversity academically and in life? This workshop will detail the research of Dr. Carol Dweck and her groundbreaking work on the concept of mindset. Students will learn how to abandon a debilitating fixed mindset in favor of a growth mindset, leading to success in areas they once considered too difficult. The workshop will also introduce students to the research of Dr. Angela Duckworth, and how a growth mindset can lead to the development of grit, an essential characteristic to overcoming our fear of failure.

Register at: myumi.ch/DEDPD

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Workshop / Seminar Mon, 11 Jan 2021 11:23:23 -0500 2021-01-27T16:00:00-05:00 2021-01-27T17:30:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar growth and grit
Special Physics Department MLK Colloquium | Equity in Science: Representation, Culture, and the Dynamics of Change in Graduate Education (January 27, 2021 4:00pm) https://events.umich.edu/event/79793 79793-20499783@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: Department Colloquia

STEM disciplines are believed to be founded on the idea of meritocracy; recognition earned by the value of the data, which is objective. Such disciplinary cultures resist concerns about implicit or structural biases, and yet, year after year, scientists observe persistent gender and racial inequalities in their labs, departments, and programs. In this colloquium, Julie Posselt makes the case that understanding field-specific cultures is a crucial step for bringing about real change and that we can learn as much from quantum as classical dynamics about the dynamics of scientific organizations. She will share research that compares equity, diversity, and inclusion efforts in astronomy and physics, and the subtle ways that exclusion and power operate in scientific organizations and, sometimes, within change efforts themselves.

Julie Posselt's bio:
Dr. Julie Posselt received her Ph.D. from the University of Michigan School of Education and is currently an Associate Professor of higher education in the USC Rossier School of Education. Specializing in graduate education and STEM fields, and elite undergraduate institutions, her research examines institutionalized inequities in higher education and organizational efforts aimed at reducing inequalities and encouraging diversity. She has also written a book, Inside Graduate Admissions: Merit, Diversity, and Faculty Gatekeeping (2016, Harvard University Press), based on an award-winning study of faculty judgment in ten highly ranked doctoral programs in three universities. This work has led to a partnership with USC, APS, and the Council of Graduate Schools that focuses on re-examining how we evaluate students and scholars for key academic opportunities.

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Workshop / Seminar Fri, 27 May 2022 16:14:55 -0400 2021-01-27T16:00:00-05:00 2021-01-27T17:00:00-05:00 Off Campus Location Department Colloquia Workshop / Seminar Photo of Julie Posselt
HET Brown Bag Seminar | Adventures in Non-Supersymmetric String Theory (January 28, 2021 12:00pm) https://events.umich.edu/event/81150 81150-20858312@events.umich.edu Event Begins: Thursday, January 28, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

It has long been known that there exist strings with supersymmetry on the world sheet, but not in spacetime. These include the well-known Type 0 strings, as well as a series of seven heterotic strings, all of which are obtained by imposing unconventional GSO projections. Besides these classic examples, relatively little is known about the full space of non-SUSY theories. One of the reasons why non-SUSY strings have remained understudied is the fact that nearly all of them have closed string tachyons, and hence do not admit ten-dimensional flat space as a stable vacuum. The goal of this talk is two-fold. First, using recent advances in condensed matter theory, we will reinterpret GSO projections in terms of topological phases of matter, thereby providing a framework for the classification of non-SUSY strings. Having done so, we will show that for all non-SUSY theories in which a tachyon exists, it can be condensed to give a (meta)stable lower-dimensional vacuum. In many cases, these stable vacua will be two-dimensional string theories already known in the literature.

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Lecture / Discussion Fri, 05 Feb 2021 10:22:43 -0500 2021-01-28T12:00:00-05:00 2021-01-28T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Rackham/Sweetland Workshops on Writing (January 29, 2021 8:00am) https://events.umich.edu/event/78494 78494-20452221@events.umich.edu Event Begins: Friday, January 29, 2021 8:00am
Location:
Organized By: Sweetland Center for Writing

This workshop will focus on the personal statement for fellowships applications and will provide participants an opportunity to bring examples of their statements and get feedback from their peers. Registration is required and will be limited to 20 participants. Register at https://lsa.umich.edu/sweetland/graduates/sweetland-rackham-workshops.html after December 4th.

Presented by Larissa Sano, Sweetland Center for Writing

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Workshop / Seminar Thu, 03 Dec 2020 08:52:10 -0500 2021-01-29T08:00:00-05:00 2021-01-29T09:00:00-05:00 Sweetland Center for Writing Workshop / Seminar
HEP-Astro Seminar | LHC Opportunities in Long-Lived Signatures From Hidden Sectors (February 1, 2021 4:00pm) https://events.umich.edu/event/80906 80906-20818982@events.umich.edu Event Begins: Monday, February 1, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

The LHC bears great potential in seeking hidden sector particles in the GeV to TeV scales, such as a high-quality QCD axion, glueballs, and heavy neutrinos. In this talk, I will present my recent studies on how to probe these hidden sector particles through novel features of long-lived particles.

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Workshop / Seminar Mon, 01 Feb 2021 18:15:40 -0500 2021-02-01T16:00:00-05:00 2021-02-01T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
CCMB / DCMB Weekly Seminar Series (February 3, 2021 4:00pm) https://events.umich.edu/event/81571 81571-20927558@events.umich.edu Event Begins: Wednesday, February 3, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
Understanding intra-tumour heterogeneity (ITH), in particular identifying the presence of subclonal populations of cancer cells that may respond differently to treatments, is key to support precision medicine approaches. Capturing ITH from genomic measures raises however a number of computational challenges. In this talk I will present CloneSig, a method to infer ITH from "bulk" genomic data, in particular whole-exome sequencing data, and capture changes in mutational processes active in different subclones. I will then discuss the promises of single-cell genomics and some challenges it raises, in particular to transform raw count data into useful representations, integrate heterogeneous modalities, and learn gene regulation.

Short bio: Jean-Philippe Vert has been a research scientist at Google Brain in Paris and adjunct researcher at PSL University Mines ParisTech since 2018. He graduated from Ecole Polytechnique and holds a PhD in mathematics from Paris University. He was research professor and the founding director of the Centre for Computational Biology at Mines ParisTech from 2006 to 2018, team leader at the Curie Institute on computational biology of cancer (2008-2018), visiting scholar at UC Berkeley (2015-2016), and professor at the department of mathematics of Ecole normale supérieure in Paris (2016-2018).
His research interest concerns the development of statistical and machine learning methods, particularly to model complex, high-dimensional and structured data, with an application focus on computational biology, genomics and precision medicine. His recent contributions include new methods to embed structured data such as strings, graphs or permutations to vector spaces, regularization techniques to learn from limited amounts of data, and computationally efficient techniques for pattern detection and feature selection.
He is also working on several medical applications in cancer research, including quantifying and modeling cancer heterogeneity, predicting response to therapy, and modeling the genome and epigenome of cancer cells at the single-cell level.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 01 Feb 2021 14:12:04 -0500 2021-02-03T16:00:00-05:00 2021-02-03T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Jean-Philippe Vert, PhD (Research Scientist at Google Brain in Paris, Adjunct Researcher at PSL University Mines ParisTech)
Science Success Series | Make It Stick: Research-Based Learning Strategies You Need to Know (February 3, 2021 4:00pm) https://events.umich.edu/event/80585 80585-20759746@events.umich.edu Event Begins: Wednesday, February 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Science Learning Center

The study and learning strategies students often bring to college are often insufficient to help them succeed at the university level. Particularly in challenging STEM courses, students can't simply memorize or cram their way to a good grade. This workshop will focus on the popular learning strategies to avoid, as well as the top three strategies you don't know but are shown by research to be the most effective for long-term learning.

Register at: myumi.ch/885DK

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Workshop / Seminar Mon, 11 Jan 2021 11:24:23 -0500 2021-02-03T16:00:00-05:00 2021-02-03T17:30:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar make it stick
HET Brown Bag | The black hole spectrum in (super)gravity (February 4, 2021 12:00pm) https://events.umich.edu/event/81152 81152-20858314@events.umich.edu Event Begins: Thursday, February 4, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The talk will focus on the spectrum of near-extremal black holes in gravity and near-BPS black holes in supergravity. For concreteness, we will study cases in asymptotically four-dimensional flat space and three-dimensional Anti-de Sitter. This will be done by analyzing quantum effects near the horizon captured by an emergent Jackiw-Teitelboim mode at low temperatures. This will allow us to systematically study questions such as the extremal degeneracy and the size of the gap in the black hole spectrum, which can be compared to some string theory constructions.

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Lecture / Discussion Tue, 09 Feb 2021 14:49:08 -0500 2021-02-04T12:00:00-05:00 2021-02-04T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
AIAA Winter Mass Meeting (February 4, 2021 7:00pm) https://events.umich.edu/event/81559 81559-20927549@events.umich.edu Event Begins: Thursday, February 4, 2021 7:00pm
Location: Off Campus Location
Organized By: American Institute of Aeronautics and Astronautics

Join us for our Mass Meeting this Thursday, February 4 at 7 PM as we present an overview of our org and bring everyone up to speed as to what to expect this semester as a member of AIAA! We'll briefly go over our plan, have a bite together (all attendees will be reimbursed $5 on Venmo), and then, we'll finish off the night with a game of Aerospace Kahoot! The winner gets a $15 Amazon gift card, so come PREPARED!!!

Please fill out this Google form if you are interested in becoming a member of our branch:
https://forms.gle/3a4f4qHd1E4Ta67t7

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Rally / Mass Meeting Mon, 01 Feb 2021 19:09:28 -0500 2021-02-04T19:00:00-05:00 2021-02-04T20:00:00-05:00 Off Campus Location American Institute of Aeronautics and Astronautics Rally / Mass Meeting meeting flyer
Life in Graduate School | "Understanding Taxes" (February 5, 2021 1:00pm) https://events.umich.edu/event/81539 81539-20911626@events.umich.edu Event Begins: Friday, February 5, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Physics

Virtual Seminar Link: https://umich.zoom.us/j/93968565401 passcode: "physics"


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Workshop / Seminar Fri, 05 Feb 2021 18:15:44 -0500 2021-02-05T13:00:00-05:00 2021-02-05T14:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Information Transfer with a Gravitating Bath (February 5, 2021 3:00pm) https://events.umich.edu/event/81406 81406-20893764@events.umich.edu Event Begins: Friday, February 5, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link: http://myumi.ch/O4P7E

Recent progress in our understanding of black hole evaporation
has mostly occurred in the context of black holes coupled to an
external, non-gravitating bath. In order to compare and contrast to what
happens to black holes in asymptotically flat space it is imperative to
understand whether the non-gravitating bath is just some external
spectator or actively changes the physics in this system. Equivalently,
one can wonder to what extent the results generalize to the case of a
gravitating bath. We use Randall-Sundrum braneworlds, and their
holographic interpretation, to answer this important question.

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Lecture / Discussion Thu, 28 Jan 2021 11:01:56 -0500 2021-02-05T15:00:00-05:00 2021-02-05T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | The Pursuit of Neutrino CP Violation With the T2K Experiment: Challenges and Prospects (February 8, 2021 4:00pm) https://events.umich.edu/event/81590 81590-20929542@events.umich.edu Event Begins: Monday, February 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

After a decade of operation, the T2K Collaboration published in 2020 in Nature very exciting results showing the strongest constraint yet on the parameter that governs the breaking of the symmetry between matter and antimatter using neutrino oscillations. T2K has studied how beams of muon neutrinos and antineutrinos transition into electron neutrinos and electron antineutrinos, respectively. The parameter governing the matter/antimatter symmetry breaking in neutrino oscillation, called δcp phase, can take a value from -180º to 180º. For the first time, T2K has disfavoured almost half of the possible values at the 99.7% confidence level. This outstanding result is starting to reveal a basic property of neutrinos that have not been measured until now. This is an important step on the way to knowing whether or not neutrinos and antineutrinos behave differently. In the quest of CP violation there are many challenges that compromise the performance of the T2K experiment. I will discuss the challenges and describe the possible solutions selected by the experiment to overcome these limitations.

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Workshop / Seminar Mon, 08 Feb 2021 18:15:46 -0500 2021-02-08T16:00:00-05:00 2021-02-08T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
CSCS Seminar: Universal Biology in Adaptation and Evolution: Multilevel Consistency, Dimensional Reduction, and Fluctuation-Response Relationship (February 9, 2021 7:00pm) https://events.umich.edu/event/80714 80714-20777539@events.umich.edu Event Begins: Tuesday, February 9, 2021 7:00pm
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

A special Happy Hour seminar - live from Tokyo Japan. Join us on Tuesday evening at 7:00 pm EST to hear from pre-eminent Complex Systems scientist Kunihiko Kaneko.

LOCAL U.S.A. MEETING LINK: myumi.ch/v2ZYv
FULL MEETING INVITE WITH INTERNATIONAL LINKS:
https://lsa.umich.edu/cscs/news-events/all-news/search-news/complete-seminar-join-invitation-for-complex-systems-seminar.html

Abstract:
A macroscopic theory for cellular states with steady-growth is presented, based on consistency between cellular growth and molecular replication, as well as robustness of phenotypes against perturbations. Adaptive changes in high-dimensional phenotypes are shown to be restricted within a low-dimensional slow manifold, from which a macroscopic law for cellular states is derived, as is confirmed by adaptation experiments of bacteria under stress. Next, the theory is extended to phenotypic evolution, leading to proportionality between phenotypic responses against genetic evolution and by environmental adaptation. Evolutionary relevance of slow modes in controlling high-dimensional phenotypes is discussed. Last, I will touch upon the origin of central dogma in molecular biology as symmetry breaking between function and information.

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Livestream / Virtual Tue, 09 Feb 2021 15:03:58 -0500 2021-02-09T19:00:00-05:00 2021-02-09T20:30:00-05:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Headshot of Kunihiko Kaneko
CCMB / DCMB Weekly Seminar (February 10, 2021 4:00pm) https://events.umich.edu/event/81413 81413-20893777@events.umich.edu Event Begins: Wednesday, February 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The increasing omics data and advanced AI technology present a great opportunity for novel biomarker-driven cancer therapies. My talk will cover two parts. First, I will introduce DrBioRight, a natural language-oriented and AI-driven analytic platform for omic data analysis. This platform allows users to perform analysis directly through human languages and it improves the performance through adaptive learning. Armed with NLP and AI technologies, this analytic will maximize the utility of omics data and lead to a new paradigm for biomedical research. Second, I will discuss our recent work on enhancer RNAs. We show that the eRNAs provide explanatory power for cancer phenotypes beyond that provided by mRNA expression through resolving intratumoral heterogeneity with enhancer cell-type specificity. Our study provides a high-resolution map of eRNA loci through which enhancer activities can be quantified by RNA-seq, enabling a broad range of biomedical investigations.

Bio: Dr. Liang is a Barnhart Family Distinguished Professor in Targeted Therapies and the Deputy Chair of Department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center. He is also a professor in the Department of Systems Biology. He received his B.S. in chemistry from Peking University (China) in 2001 and Ph.D. in quantitative and computational biology from Princeton University (NJ, USA) in 2006. Dr. Liang then finished his postdoctoral training in evolutionary and computational genomics at the University of Chicago. He joined MD Anderson Cancer Center as Assistant Professor and started his own group in 2009.
At MD Anderson, Dr. Liang’s group focuses on bioinformatics tool development, integrated cancer genomic analysis, regulatory RNA regulation/modification, and cancer systems biology. His systematic studies on enhancer regulation, RNA editing, functional proteomics, sex effects, and driver mutations in cancer have generated profound impacts on the biomedical research community and attracted wide attention such as The Wall Street Journal and Newsweek. The bioinformatics tools his group developed (such as TCPA, TANRIC, FASMIC, DrBioRight) collectively have >110,000 active users worldwide. Since 2010, he has published >140 papers total citation >25,000 times), including 41 corresponding-author papers in top journals such as Cell, Cancer Cell, Nature Genetics, Nature Biotechnology, and Nature Methods.
Dr. Liang has taken leadership roles in large cancer consortium projects, including chair of The Cancer Genome Atlas (TCGA) PanCanAtlas working groups, one co-leader of International Cancer Genome Consortium (ICGC) Pan-Cancer Whole Genome Analysis Project, and one co-chair of NCI Genomic Data Commons (GDC) QC working group. He won several awards including MD Anderson R. Lee Clark Fellow Award (2014), the University of Texas System STARS Award (2015), MD Anderson Faculty Scholar Award (2018), and AACR Team Science Award (2020). He is an elected Fellow of American Association for the Advancement of Science (AAAS).

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 28 Jan 2021 11:33:05 -0500 2021-02-10T16:00:00-05:00 2021-02-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Han Liang, PhD Professor and Deputy Chair, Department of Bioinformatics and Computational Biology Professor, Department of Systems Biology Barnhart Family Distinguished Professor in Targeted Therapies The University of Texas MD Anderson Cancer Center
HET Brown Bag Seminar | Supersymmetry and Computation (February 11, 2021 12:00pm) https://events.umich.edu/event/81151 81151-20949383@events.umich.edu Event Begins: Thursday, February 11, 2021 12:00pm
Location:
Organized By: Leinweber Center for Theoretical Physics

I will discuss various aspects of the interplay between supersymmetry and the theory of classical and quantum computation. I will first introduce basic elements of computational complexity theory and show that the Witten index problem is #P-complete and thus intractable. I will then discuss the role of supersymmetry in defining a special subclass of quantum algorithms and describe the "quantum Witten machine," a quantum algorithm for the generalized Witten index.

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Lecture / Discussion Thu, 04 Feb 2021 09:21:29 -0500 2021-02-11T12:00:00-05:00 2021-02-11T13:00:00-05:00 Leinweber Center for Theoretical Physics Lecture / Discussion
HET Seminar | Looking for new physics in the neutrino sector (February 12, 2021 3:00pm) https://events.umich.edu/event/81548 81548-20925390@events.umich.edu Event Begins: Friday, February 12, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link: http://myumi.ch/O4P7E

I will briefly review the motivation for the existence of new physics
in the neutrino sector and I will describe a few different ways of
looking for such new physics.

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Lecture / Discussion Tue, 02 Feb 2021 14:34:11 -0500 2021-02-12T15:00:00-05:00 2021-02-12T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro | Latest Developments in Higgs Physics (February 15, 2021 4:00pm) https://events.umich.edu/event/81620 81620-20935491@events.umich.edu Event Begins: Monday, February 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Eight years after the discovery of the Higgs boson at the LHC, we are still trying to unwrap all its secrets. It has become a valuable tool in the search for physics beyond the Standard Model. I will discuss current "hot topics" in Higgs physics, with a focus on experimental aspects. Examples are the search for rare decays, the analysis of the CP structure of the Higgs boson, and the Higgs boson as part of an effective field theory. Search highlights include invisible decays of the Higgs boson, as well as Dihiggs production. I will try to touch upon some theoretical aspects as well.

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Workshop / Seminar Mon, 15 Feb 2021 18:15:57 -0500 2021-02-15T16:00:00-05:00 2021-02-15T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Department Colloquium | The Proton Remains Puzzling (February 17, 2021 4:00pm) https://events.umich.edu/event/81714 81714-20945432@events.umich.edu Event Begins: Wednesday, February 17, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Link: http://myumi.ch/GkgBm

Nucleons (protons and neutrons) are the building blocks of atomic nuclei and are responsible for more than 99% of the visible matter in the universe. Despite decades of efforts in studying its internal structure, there are still a number of puzzles surrounding the proton such as its spin and the charge radius. The proton charge radius puzzle developed more than 10 ten years ago refers to a discrepancy of 5-7 standard deviations between the ultrahigh precise values of the proton charge radius determined from muonic hydrogen Lamb shift measurements and the CODATA values compiled from electron-proton scattering experiments and ordinary hydrogen spectroscopy measurements. In this talk following a short introduction, I will focus on the proton charge radius puzzle, the latest experimental results, especially those from the PRad experiment at Jefferson Lab, and the future outlook with the PRad-II experiment.

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Workshop / Seminar Wed, 17 Feb 2021 18:15:58 -0500 2021-02-17T16:00:00-05:00 2021-02-17T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Special Joint Seminar between our Department and the Genome Science Training Program (February 17, 2021 4:00pm) https://events.umich.edu/event/80415 80415-20719669@events.umich.edu Event Begins: Wednesday, February 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The human genome sequence folds in three dimensions (3D) into a rich variety of locus-specific contact patterns. Despite growing appreciation for the importance of 3D genome folding in evolution and disease, we lack models for relating mutations in genome sequences to changes in genome structure and function. Towards that goal, we discovered that the organization of gene regulatory domains within chromosomes and the specific sequences that sit at boundaries between domains are under strong negative selection in the human population and over primate evolution. Motivated by this signature of functional importance, we developed a deep convolutional neural network, called Akita, that accurately predicts genome folding from DNA sequence alone. Representations learned by Akita underscore the importance of the structural protein CTCF but also reveal a complex grammar beyond CTCF binding sites that underlies genome folding. Akita enabled rapid in silico predictions for effects of sequence mutagenesis on the 3D genome, including differences in genome folding across species and in disease cohorts, which we are validating with CRISPR-edited genomes. This prediction-first strategy exemplifies my vision for a more proactive, rather than reactive, role for data science in biomedical research.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

Short bio: Dr. Katherine S. Pollard is Director of the Gladstone Institute of Data Science & Biotechnology, Investigator at the Chan Zuckerberg Biohub, Professor in the Department of Epidemiology & Biostatistics and Bioinformatics Graduate Program at UCSF. Her lab develops statistical models and open source bioinformatics software for the analysis of massive genomic datasets. Previously, Dr. Pollard was an assistant professor in the University of California, Davis Genome Center and Department of Statistics. She earned her PhD in Biostatistics from the University of California, Berkeley and was a comparative genomics postdoctoral fellow at the University of California, Santa Cruz. She was awarded the Thomas J. Watson Fellowship, the Sloan Research Fellowship, and the Alumna of the Year from UC Berkeley. She is a Fellow of the International Society for Computational Biology and of the California Academy of Sciences.

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Livestream / Virtual Wed, 06 Jan 2021 09:24:05 -0500 2021-02-17T16:00:00-05:00 2021-02-17T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Katherine S. Pollard, PhD (Director, Gladstone Institute of Data Science & Biotechnology; Professor, UCSF; Investigator, Chan Zuckerberg Biohub)
Science Success Series | Medical School Student Panel Discussion (February 18, 2021 6:30pm) https://events.umich.edu/event/80634 80634-20769609@events.umich.edu Event Begins: Thursday, February 18, 2021 6:30pm
Location: Off Campus Location
Organized By: Science Learning Center

Here is your chance to hear about what life is like for several medical school students and residents. Learn about each of their paths to medicine, experiences in various medical schools, and things they wished they had known in college.

Panelists:

Jasmine D.Johnson, M.D., FACOG/Clinical Instructor & Fellow UNC Department of Obstetrics & Gynecology/ Division of Maternal-Fetal Medicine

Eric Poole. Rising M3, Michigan State University College of Human Medicine

Register at: myumi.ch/Wwm09

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Workshop / Seminar Tue, 12 Jan 2021 12:14:31 -0500 2021-02-18T18:30:00-05:00 2021-02-18T19:30:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar book and stethoscope
HET Seminar | Generalized symmetries and holography in supersymmetric Chern-Simons theories (February 19, 2021 3:00pm) https://events.umich.edu/event/81407 81407-20893766@events.umich.edu Event Begins: Friday, February 19, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link: http://myumi.ch/O4P7E

In this talk I will revisit holographic duality for maximally supersymmetric 3d Chern-Simons gauge theories.
By revealing the generalized global symmetries of the field theories I will provide a unified picture of holography that
incorporates all known theories.

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Lecture / Discussion Tue, 09 Feb 2021 08:43:59 -0500 2021-02-19T15:00:00-05:00 2021-02-19T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Saturday Morning Physics VIRTUAL Event | Weighing and Counting Giants in the Sky (February 20, 2021 10:30am) https://events.umich.edu/event/80680 80680-20775536@events.umich.edu Event Begins: Saturday, February 20, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

Maria Elidaiana da Silva Pereira will give a "live" lecture with a "live" Q&A after the talk.
Virtual Presentation Link: https://www.youtube.com/watch?v=9h8l_Pl9xLQ (Link will be active at 10:30 am on 02/20/21.)

Galaxy Clusters are the largest astronomical objects in the Universe. These cosmic giants are bound together by gravity and are formed by galaxies, hot gas, and mysterious dark matter. By counting them and measuring their masses, we can understand the content and evolution of the Universe. In this talk, I will present how we can use light for weighing galaxy clusters. I will also show how the Dark Energy Survey uses them to measure the quantity of dark matter and properties of the even more mysterious component, the dark energy.

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Lecture / Discussion Thu, 18 Feb 2021 13:48:00 -0500 2021-02-20T10:30:00-05:00 2021-02-20T11:30:00-05:00 Off Campus Location Saturday Morning Physics Lecture / Discussion Photo of Maria Elidaiana da Silva Pereira
Special Quantitative Biology Seminar | Interaction of Weakly Active Particles With Boundaries in Different Geometries (February 22, 2021 12:00pm) https://events.umich.edu/event/82272 82272-21062641@events.umich.edu Event Begins: Monday, February 22, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link: https://umich.zoom.us/j/91439466230?pwd=S3FSUW5FcEMvT0puaXhSekRIK2R4QT09

Active particles consume fuel to propel around and interact with their environments. This behavior gives rise to a myriad of fascinating out-of-equilibrium phenomena such as phase separation in the absence of attractive interactions and directional transport through funnel-shaped obstacles or around gear-like objects. I will start by giving a brief overview of my research studying how the physics of passive/equilibrium systems changes as one gradually increases the level of activity. I will then focus on how weakly active particles behave near different types or shapes of boundaries in various geometries. A weakly active particle is one where regular diffusion cannot be neglected and activity can be treated perturbatively. This limit of weak activity allows us to develop a relatively simple method for analytically calculating properties such as the density, orientations, and flows of these particles near boundaries. I will show that this method is quite versatile by applying it to weakly active particles in several geometries: (1) confinement in 1D, (2) confinement in a wedge-shaped region, (3) absorption around a sphere, and finally (4) flows near a rough boundary. These results in the limit of weak activity provides some insight into how active particles behave near boundaries.


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Workshop / Seminar Mon, 22 Feb 2021 18:15:58 -0500 2021-02-22T12:00:00-05:00 2021-02-22T13:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HEP-Astro Seminar | The case for FCC-ee (February 22, 2021 4:00pm) https://events.umich.edu/event/82056 82056-21014660@events.umich.edu Event Begins: Monday, February 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

A new circular e+e- collider hosted in a 100 km tunnel, FCC-ee, produces high luminosity for top-quark, Higgs boson, W and Z boson studies, accommodates multiple detectors and can reach energies up to the top-pair threshold and beyond. It will enable measurements of unequaled precision, offering the exploration of physics beyond the Standard Model in the multi-TeV range. Moreover, being the natural precursor of FCC-hh, a 100 TeV hadron collider in the same tunnel, it builds up a long-term vision for particle physics. With this talk, I will make the case for FCC-ee by discussing the physics landscape and show the opportunities of the project.

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Workshop / Seminar Mon, 22 Feb 2021 18:15:58 -0500 2021-02-22T16:00:00-05:00 2021-02-22T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Science Success Series | Ace Your Courses: Metacognition is Key! (February 22, 2021 4:00pm) https://events.umich.edu/event/80592 80592-20759749@events.umich.edu Event Begins: Monday, February 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Science Learning Center

Have you ever found yourself putting forth a great deal of effort into your courses, but not feeling like you are actually learning or are left unsatisfied with your grade? This workshop, based on the work of Dr. Saundra Yancy McGuire, will enable you to analyze your current learning strategies, understand exactly what changes you need to implement to earn an A in your courses, identify concrete strategies to use during the remainder of your semester, and become a more efficient learner.

Register at: myumi.ch/9o7zb

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Workshop / Seminar Mon, 11 Jan 2021 11:32:51 -0500 2021-02-22T16:00:00-05:00 2021-02-22T17:30:00-05:00 Off Campus Location Science Learning Center Workshop / Seminar Teach Yourself How to Learn
Complex Systems Seminar: 'Low rattling: A predictive principle for self-organization in active collectives' (February 23, 2021 11:30am) https://events.umich.edu/event/80724 80724-20777541@events.umich.edu Event Begins: Tuesday, February 23, 2021 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

VIRTUAL SEMINAR LINK: https://umich.zoom.us/j/96616169868

ABSTRACT: In this work we suggest a mechanism for self-organization of active matter, which we believe may be quite general. This mechanism is similar in spirit to thermophoretic drift in colloidal suspensions, where particles gravitate to low-temperature regions. The difference is that here instead of suspended particles in a bath, we think of the dynamics of a complex system's state in its full high-dimensional configuration space. The temperature landscape is then replaced by what we call "Rattling landscape," which reflects how different system states respond to the driving forces. This way the system gravitates towards configurations that have special response properties to the external forces, giving the impression that it "adapts to its environment." As a proof of principle, we use our theory to predict and control the behavior of a simple robotic swarm.

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Livestream / Virtual Thu, 18 Feb 2021 11:46:19 -0500 2021-02-23T11:30:00-05:00 2021-02-23T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Pavel Chvykov
HET Brown Bag | Consistency of the Standard Model Effective Field Theory (February 24, 2021 12:00pm) https://events.umich.edu/event/82009 82009-21004775@events.umich.edu Event Begins: Wednesday, February 24, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

In this talk I will describe how the analytic structure of scattering amplitudes impose non-trivial constraints on the standard model effective field theory (SMEFT). For example, in the bosonic sector, I will explain how the bounds imply restrictions on the size of certain CP-odd operators by associated CP-even couplings. This result can be exploited to reveal a connection between constraints derived at colliders and limits on the neutron electric dipole moment. Further, I will demonstrate that in the fermionic sector, IR consistency requires that flavour violating operators are bounded by the flavour conserving variants. While most results will be presented for the SMEFT at dimension 8, I will also describe recent progress allowing a subset of the results to be lifted to dimension 6.

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Lecture / Discussion Wed, 10 Mar 2021 15:19:30 -0500 2021-02-24T12:00:00-05:00 2021-02-24T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
CCMB / DCMB Weekly Seminar (February 24, 2021 4:00pm) https://events.umich.edu/event/82197 82197-21052530@events.umich.edu Event Begins: Wednesday, February 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: COVID Moonshot is an international consortium aiming to discover patent-free oral antiviral against SARS-CoV-2, targeting the main protease. Operating under an open science ethos, we make all data and structures publicly available, and crowdsource molecule designs from the community. In less than a year, we went from fragment hits to nanomolar leads in biochemical and antiviral assays. In my talk, I will discuss Moonshot’s journey towards orally bioavailable, non-covalent, and non-peptidomimetic Mpro inhibitors. I will discuss how machine learning technologies have accelerated our design-make-test cycle, and the learnings we gleaned from this large-scale prospective use of algorithms.

Bio: Dr. Alpha Lee is a Group Leader in the Department of Physics, University of Cambridge. His research focuses on developing machine learning technologies that close the design-make-test cycle for small molecule drug discovery and materials discovery. He is interested in how physical and chemical insights can be integrated into the design of interpretable algorithms. Before joining Cambridge, Dr. Lee was a Fulbright Scholar at Harvard and obtained his PhD from the University of Oxford.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 17 Feb 2021 13:18:31 -0500 2021-02-24T16:00:00-05:00 2021-02-24T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
HET Brown Bag Seminar | Worldsheet g-function and AdS/CFT (February 25, 2021 12:00pm) https://events.umich.edu/event/81216 81216-20872040@events.umich.edu Event Begins: Thursday, February 25, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Recently there has been new progress in computing a class of observables in N=4 supersymmetric Yang-Mills theory in four dimensions at finite 't Hooft coupling, ranging from correlation functions of "baryonic" operators to leading instanton effects at large N. All those examples share two common features: 1. At weak coupling, they can be computed by an overlap between a matrix product state and an eigenstate of the Hamiltonian of an integrable 1+1d spin chain. 2. Using AdS/CFT, they can be mapped to so-called g-functions on the string worldsheet and can be computed exactly as a function of 't Hooft coupling. After explaining the basic ideas, I will showcase several applications.

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Lecture / Discussion Fri, 26 Feb 2021 12:23:17 -0500 2021-02-25T12:00:00-05:00 2021-02-25T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
LAGS Seminar | How I used my physics background in the real world. (February 26, 2021 1:00pm) https://events.umich.edu/event/82441 82441-21100189@events.umich.edu Event Begins: Friday, February 26, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Dave got his Ph.D. in Physics, during which time he decided that there was a whole world of things to do outside of academia when he graduated. He and his wife, who received a Ph.D. in Biochemistry, loaded up the car and moved to Seattle, where he found a job as a Project Manager at a small internet retailer called Amazon.com. How does this relate to a Physics degree? In Physics, we are taught to think from first principles and break down problems to their fundamentals. This can be applied to just about anything -- logistics, software development, people leadership. Dave will talk about how he used his background in Physics to do all of these things. This will be a casual discussion where he will answer students’ questions.

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Workshop / Seminar Fri, 26 Feb 2021 18:15:42 -0500 2021-02-26T13:00:00-05:00 2021-02-26T14:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HEP-Astro Seminar | Extracting the Most From Collider Data With Deep Learning (March 1, 2021 4:00pm) https://events.umich.edu/event/82057 82057-21014661@events.umich.edu Event Begins: Monday, March 1, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Precise scientific analysis in collider-based particle physics is possible because of complex simulations that connect fundamental theories to observable quantities. These simulations have been paired with multivariate methods for many years in search of the smallest distance scales in nature. Deep learning tools hold great promise to qualitatively change this paradigm by allowing for holistic analysis of data in its natural hyperdimensionality with thousands or millions of features instead of up to tens of features. These tools are not yet broadly used for all areas of data analysis because of the traditional dependence on simulations. In this talk, I will discuss how we can change this paradigm in order to exploit the new features of deep learning to explore nature at sub-nuclear distance scales. In particular, I will show how neural networks can be used to (1) overcome the challenge of intractable hypvervariate probability density modeling and (2) learn directly from (unlabeled) data to perform hypothesis tests that go beyond any existing analysis methods. The example for (1) will be full phase space unfolding and the example for (2) will be anomaly detection. The talk will include a discussion of uncertainties associated with deep learning-based analyses.

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Workshop / Seminar Mon, 01 Mar 2021 18:15:37 -0500 2021-03-01T16:00:00-05:00 2021-03-01T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Department Colloquium | Population Properties of Compact Objects From the Second LIGO-Virgo Gravitational-Wave Transient Catalog (March 3, 2021 4:00pm) https://events.umich.edu/event/82525 82525-21116076@events.umich.edu Event Begins: Wednesday, March 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Link: http://myumi.ch/GkgBm

When two black holes merge, the resulting gravitational waveform encodes information about the black hole masses and spins. By studying how binary black holes are distributed in mass, spin, and distance, it is possible to probe the fate of massive stars while gaining insights into how compact binaries are assembled. In this talk, I report on the population properties of 47 compact binaries included in the recently published LIGO-Virgo gravitational-wave transient catalog two (GWTC-2). I highlight two key results. First, we find evidence for a feature (a bump or a kink) in the primary black hole mass spectrum at around 35 solar masses. This feature may be related to pair instability supernovae. Second, we find that 12-44% of binary black hole mergers contain black holes with spin vectors tilted by more than 90° away from the orbital angular momentum. This may indicate that at least some binary black holes are assembled dynamically in dense stellar environments. I discuss the implications of these results and highlight emerging questions in gravitational-wave astronomy.

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Workshop / Seminar Wed, 03 Mar 2021 18:15:49 -0500 2021-03-03T16:00:00-05:00 2021-03-03T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Quantum Complexity, Integrability, and Chaos (March 4, 2021 12:00pm) https://events.umich.edu/event/81845 81845-20982931@events.umich.edu Event Begins: Thursday, March 4, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link: http://myumi.ch/O4P7E

The states of quantum systems grow in complexity over time as entanglement spreads between degrees of freedom. Following ideas in computer science, we formulate the complexity of time evolution as the length of the shortest geodesic on the unitary group manifold between the identity and the time evolution operator, and use the SYK family of models with N fermions to study this quantity in free, integrable, and chaotic systems. In all cases, the complexity initially grows linearly in time, and the shortest path lies along the physical time evolution. This linear growth is eventually truncated by "shortcuts" on the unitary manifold that are shorter than the physical time evolution. We explicitly locate such shortcuts and hence show that in the free theory, shortcuts occur at a time of O(N^1/2), truncating complexity growth at this scale. We also find an explicit operator which "fast-forwards" time evolution with this complexity. In a class of integrable theories, we show that shortcuts appear in a time upper bounded by O(poly(N)), again truncating complexity growth. Finally, in chaotic theories we argue that shortcuts do not occur until exponential times, after which it becomes possible to find infinitesimally nearby fixed-complexity approximations to the time evolution operator. We relate these results to the Eigenstate Complexity Hypothesis, a new criterion on the spectrum of energy eigenstates that guarantees an exponential increase of complexity over time that is consistent with maximal chaos.

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Lecture / Discussion Wed, 10 Mar 2021 15:21:51 -0500 2021-03-04T12:00:00-05:00 2021-03-04T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Professor Steven Cundiff, the Harrison M. Randall Collegiate Professorship in Physics, Inaugural Lecture (March 4, 2021 4:00pm) https://events.umich.edu/event/81662 81662-20941444@events.umich.edu Event Begins: Thursday, March 4, 2021 4:00pm
Location: Off Campus Location
Organized By: Institute of Electrical and Electronics Engineers

Just over 20 years ago, the demonstration of self-referenced optical frequency combs solved a long-standing problem of linking radio- and light-frequencies. This breakthrough allowed direct measurement of the frequency of light and enabled optical atomic clocks with exquisite precision. The development of dual-comb techniques led to a second wave of activity over the last ten years. Dual comb techniques enable rapid, high-resolution spectroscopy that can be used for applications such as atmospheric monitoring or breath analysis. I will explain what an optical frequency comb is, how they are generated and used, and present some of our recent work on them.

Please click the link below to join the webinar:
https://umich.zoom.us/j/96244808495
Or iPhone one-tap :
US: +13126266799,,96244808495# or +16468769923,,96244808495#
Or Telephone:
Dial(for higher quality, dial a number based on your current location):
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Webinar ID: 962 4480 8495
International numbers available: https://umich.zoom.us/u/adlbPeZ0l3

Or an H.323/SIP room system:
H.323:
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Meeting ID: 962 4480 8495
SIP: 96244808495@zoomcrc.com

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Lecture / Discussion Tue, 02 Mar 2021 09:15:13 -0500 2021-03-04T16:00:00-05:00 2021-03-04T17:00:00-05:00 Off Campus Location Institute of Electrical and Electronics Engineers Lecture / Discussion Image
Biophysics Seminar Series (March 5, 2021 12:00pm) https://events.umich.edu/event/79991 79991-20539092@events.umich.edu Event Begins: Friday, March 5, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Samuel Butcher - Steenbock Professor of Biomolecular Structure, Department of Biochemistry, University of Wisconsin-Madison

*“The epitranscriptome has been shaped by the co-evolution of RNA writer and reader proteins.”*

ABSTRACT: The epitranscriptome is characterized by dozens of post-transcriptional chemical modifications to RNA.  These chemical modifications are catalyzed by enzymes, or “writers” that chemically mark both coding and non-coding RNAs.  The post-transcriptional marks are then read by protein “readers” that bind to the RNA modifications and help direct their cognate RNAs towards different pathways in the cell. I will present our work showing how RNA writers
and readers have co-evolved to shape the epitranscriptome input and output. A series of comparative molecular structures will be described that illustrate how very subtle changes in enzyme active sites of RNA modifying enzymes result in different chemical marks that have co-
evolved with RNA reader proteins, which can adopt modular quaternary structures that are specifically tuned to read different modifications. This co-evolution of RNA writers and readers impacts nearly every step of eukaryotic gene expression.

*Join us on Zoom: https://umich.zoom.us/j/92759610297*

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Livestream / Virtual Tue, 02 Mar 2021 16:25:38 -0500 2021-03-05T12:00:00-05:00 2021-03-05T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Samuel Butcher
HEP-Astro Seminar | The Asymmetry of Antimatter in the Proton (March 8, 2021 4:00pm) https://events.umich.edu/event/82639 82639-21149734@events.umich.edu Event Begins: Monday, March 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Even after more than 100 years of studies, the proton is puzzling. Questions such as what is the exact size of the proton, how does the spin and the mass of the proton arise, and what is the exact composition of the proton still captivate our field. In the simplest picture, the proton is made of two up and one down quark, in a more comprehensive picture, however, the proton is a strongly-coupled, relativistic, infinite-body system, where quarks and antiquarks come in and out of existence for very short times. Their fleeting existence makes the antiquarks within protons difficult to study, but it is discernible in reactions in which a matter–antimatter quark pair annihilates. In this presentation, I will discuss a recent result published by the SpinQuest collaboration that shows that nature prefers anti-down quarks to anti-up quarks in the proton. This is in contrast to predictions from perturbative QCD where no such antiquark imbalance is expected in the proton.

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Workshop / Seminar Mon, 08 Mar 2021 18:15:53 -0500 2021-03-08T16:00:00-05:00 2021-03-08T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
HET Brown Bag Seminar | Loops and Trees in Generic 4d EFT up to operator dimension 8 (March 10, 2021 12:00pm) https://events.umich.edu/event/82342 82342-21068624@events.umich.edu Event Begins: Wednesday, March 10, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

I will talk about the tree and one-loop behavior in a generic 4d EFT of massless scalars, fermions, and vectors, with a particular eye to the high-energy limit of the Standard Model EFT at operator dimensions 6 and 8. First, I will show how to classify the possible Lorentz structures of operators and the subset of these that can arise at tree-level in a weakly coupled UV completion. Then I will show how operators contribute to tree and one-loop helicity amplitudes, exploring the impact of non-renormalization theorems through dimension 8 and helicity selection rules through the full one loop amplitude.

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Lecture / Discussion Thu, 11 Mar 2021 08:22:56 -0500 2021-03-10T12:00:00-05:00 2021-03-10T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
CCMB / DCMB Weekly Seminar Series (March 10, 2021 4:00pm) https://events.umich.edu/event/82479 82479-21108092@events.umich.edu Event Begins: Wednesday, March 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Single-cell technologies have transformed biomedical research in the last few years. With single-cell sequencing, we can now simultaneously measure thousands of genomics features in a large number of cells, which provides an ultrahigh resolution phenotypic map for each individual. However, single-cell protocols are complex. Even with the most sensitive platforms, the data are often sparse and noisy. Recent development of single-cell multi-omics and spatial transcriptomics technologies further imposed additional challenges on data integration. In this talk, I will present several machine learning methods that my group recently developed for single-cell and spatial transcriptomics data analysis. I will discuss methods for simultaneous denoising, clustering and batch effect correction, single-cell multi-omics data integration, identification of spatially variable genes, generation of super-resolution gene expression, and inference of cell type distribution in spatial transcriptomics. I will illustrate our methods by showing results from ongoing collaborations on cardiometabolic disease and applications to brain and cancer data.
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Biography: Dr. Li’s research interests include statistical genetics and genomics, bioinformatics, and computational biology. The central theme of her current research is to use statistical and computational approaches to understand cellular heterogeneity in human-disease-relevant tissues, to characterize gene expression diversity across cell types, to study the patterns of cell state transition and crosstalk of various cells using data generated from single-cell and spatial transcriptomics studies, and to translate these findings to the clinics. In addition to methods development, Dr. Li is also interested in collaborating with researchers seeking to identify complex disease susceptibility genes and acting cell types. She is Director of Biostatistics for the Gene Therapy Program at Penn, where she advises biostatistics and bioinformatics analysis for various gene therapy studies. She is also Chair of the Graduate Program in Biostatistics. Dr. Li actively serves in the scientific community. She served as a regular member for the NIH Genomics, Computational Biology and Technology (GCAT) study section for 6 years, and the NHGRI Center for Inherited Disease Research (CIDR) for 3 years. She is an Associate Editor of Annals of Applied Statistics, Statistics in Biosciences, PLOS Computational Biology, and Human Genetics and Genomics Advances. She is an elected member of the International Statistical Institute and a Fellow of the American Statistical Association.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 24 Feb 2021 12:57:46 -0500 2021-03-10T16:00:00-05:00 2021-03-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
MCAIM Colloquium | Slowly Chaotic Behavior (March 10, 2021 4:00pm) https://events.umich.edu/event/82673 82673-21155687@events.umich.edu Event Begins: Wednesday, March 10, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

How can we understand chaotic behavior mathematically? A well popularized feature of chaotic systems is the butterfly effect: a small variation of initial conditions may lead to a drastically different future evolution, a mechanism at the base of the so-called 'deterministic chaos'. We will introduce and focus on 'slowly chaotic' dynamical systems', for which the butterfly effect happens "slowly" (e.g. at polynomial speed). These include many fundamental examples coming from physics, such as the Ehrenfest billiard and the Novikov model of electrons in a metal. In the talk we will survey some of the recent advances in our understanding of their typical chaotic features as well as common mechanisms for chaos.

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Lecture / Discussion Tue, 02 Mar 2021 13:06:16 -0500 2021-03-10T16:00:00-05:00 2021-03-10T17:00:00-05:00 Off Campus Location Michigan Center for Applied and Interdisciplinary Mathematics Lecture / Discussion Corinna Ulcigrai, University of Zurich, Institute for Mathematics
HET Brown Bag Seminar | Kaluza-Klein Spectrometry for String Theory Compactifications (March 11, 2021 12:00pm) https://events.umich.edu/event/81153 81153-20858315@events.umich.edu Event Begins: Thursday, March 11, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

In this talk, I will present a powerful new method for computing the Kaluza-Klein spectrum of string theory compactifications. This includes geometries with little to no remaining symmetries, hardly accessible to standard methods. I will discuss various applications of this method, including to non-supersymmetric AdS_4 vacua. As I will show, some of these AdS vacua are unstable due to tachyonic Kaluza-Klein modes, while others can be proven to be perturbatively stable. Finally, I will also discuss applications to supersymmetric AdS vacua and the AdS/CFT correspondence

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Lecture / Discussion Wed, 24 Mar 2021 08:10:26 -0400 2021-03-11T12:00:00-05:00 2021-03-11T13:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HET Seminar | How to constrain your favo(u)rite theory (March 12, 2021 3:00pm) https://events.umich.edu/event/82343 82343-21068625@events.umich.edu Event Begins: Friday, March 12, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar Link: http://myumi.ch/O4P7E

LHC searches typically publish limits on not only specific models, but specific scenarios within a model. For a theorist to confront a different model or scenario to the latest limits therefore requires a whole chain of tools and calculations to map from Lagrangian parameters to data. With the immense range of possible models now under consideration this begs for automation and genericity. Along with an overview of the state of the art of this toolchain, I will review my recent work, in particular on generic unitarity calculations in the context of the SARAH package; and on recasting both prompt and long-lived LHC searches for electroweakinos so that they can be applied to any model.

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Lecture / Discussion Wed, 10 Mar 2021 15:20:59 -0500 2021-03-12T15:00:00-05:00 2021-03-12T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | The milliQan Experiment: Search for Millicharged Particles at the LHC (March 15, 2021 4:00pm) https://events.umich.edu/event/82793 82793-21179561@events.umich.edu Event Begins: Monday, March 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Arising in hidden sector models of dark matter, millicharged particles may be produced copiously at the LHC. However, due to their very small energy depositions, general purpose detectors are blind to such particles. In order to provide sensitivity, the milliQan experiment consists of several layers of long scintillator bars pointing towards the CMS interaction point, paired with high-gain, low-noise photomultiplier tubes capable of measuring a single scintillation photon. In 2017, a 1% scale "demonstrator" was installed at the planned site in order to study the feasibility and develop understanding of the experiment. The demonstrator ran very successfully, allowing a search to be undertaken that set competitive constraints and providing critical insights for future detectors. In this talk I will discuss the general concept of the experiment, the results from the demonstrator, and the plan for future detectors at the LHC and beyond.

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Workshop / Seminar Mon, 15 Mar 2021 18:15:36 -0400 2021-03-15T16:00:00-04:00 2021-03-15T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Science Success Series | Overcoming the Fear of Failure in Personal and Academic Pursuits (March 16, 2021 4:00pm) https://events.umich.edu/event/80594 80594-20759752@events.umich.edu Event Begins: Tuesday, March 16, 2021 4:00pm
Location: Off Campus Location
Organized By: Science Learning Center

In this workshop, we'll build on the lessons of growth mindset and put failure into practice, with activities that allow us to focus on the learning that goes along with mistakes. This way, we can create environments that allow for innovation, personal, and professional growth.

Register at: myumi.ch/1pBpO

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Workshop / Seminar Mon, 11 Jan 2021 11:37:45 -0500 2021-03-16T16:00:00-04:00 2021-03-16T17:30:00-04:00 Off Campus Location Science Learning Center Workshop / Seminar you can('t) do it
CCMB / DCMB Weekly Seminar Series featuring Sriram Chandrasekaran (Assistant Professor, Biomedical Engineering) (March 17, 2021 4:00pm) https://events.umich.edu/event/82825 82825-21179592@events.umich.edu Event Begins: Wednesday, March 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Drug combinations have the potential to greatly expand our pharmacopeia while reducing both cost and drug resistance. Yet the current drug-discovery approach is unable to screen the astronomical number of possible combinations in different cell types and does not account for the complex environment inside the body. We have developed AI tools - INDIGO and MAGENTA - that predict the efficacy of drug combinations based on the properties of the drugs, the pathogen, and the infection environment. We are also using modeling to identify drugs that work in synergy with the host immune system. Using INDIGO and MAGENTA, we have identified highly synergistic combinations of repurposed drugs to treat drug resistant infections including Tuberculosis, the deadliest bacterial infection. INDIGO also accurately predicts the outcome of past clinical trials of drug combinations. Our ultimate goal is to create a personalized approach to treat infections using AI.
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Biography: Chandrasekaran received his bachelor’s degree in Biotechnology from Anna University in 2008, and a PhD in Biophysics from the University of Illinois at Urbana-Champaign in 2013. He worked at Harvard University and MIT as a Harvard Junior Fellow between 2013 and 2016 and became an Assistant Professor at UM in 2017. His lab develops systems biology algorithms for drug discovery. Computer models from his lab like INDIGO and MAGENTA are being used to design effective therapies against drug resistant pathogens. His lab also develops systems biology algorithms to understand metabolic regulation. The approaches that they have created (PROM, ASTRIX, DFA, EGEM and GEMINI) perform complementary functions in modeling of metabolic and regulatory networks. Chandrasekaran’s research has been published in Cell, Genome Biology, mBio, and PNAS. For his work, Chandrasekaran previously received the 2013 Harvard Junior Fellowship, the 2011 Howard Hughes Medical Institute (HHMI) International Predoctoral Fellowship, the 2014 William Milton Fund award, 2018 UM Precision Health Investigator Award, and the 2018 Distinguished Young Investigator Award from the AICHE COBRA society.


https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 05 Mar 2021 14:44:14 -0500 2021-03-17T16:00:00-04:00 2021-03-17T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Sriram Chandrasekaran, PhD (Assistant Professor, Biomedical Engineering)
Department Colloquium | Dark Matter Meets Condensed Matter (March 17, 2021 4:00pm) https://events.umich.edu/event/82569 82569-21124010@events.umich.edu Event Begins: Wednesday, March 17, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Link: http://myumi.ch/GkgBm

As the gravitational evidence accumulates inexorably that dark matter comprises the vast majority of the mass of the universe, the particle nature of dark matter remains a mystery. New laboratory experiments are being commissioned to probe dark matter lighter than the proton mass, but the signatures in these detectors rely crucially on the condensed matter properties of the detector material. I will survey the progress made in understanding existing detectors and designing future ones which operate in this unusual low-energy regime, driven by an incredibly fruitful and rich collaboration between condensed matter physicists and particle physicists, both theorists and experimentalists. I will describe a new approach which helps to identify novel condensed matter systems with optimal material properties for dark matter detection, bridging high- and low-energy physics and ensuring that no stone is left unturned in the hunt for dark matter in the laboratory.

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Workshop / Seminar Wed, 17 Mar 2021 18:15:31 -0400 2021-03-17T16:00:00-04:00 2021-03-17T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Lifetimes of (near-)eternal false vacua (March 19, 2021 12:00pm) https://events.umich.edu/event/82928 82928-21225224@events.umich.edu Event Begins: Friday, March 19, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar link : http://myumi.ch/O4P7E
We're used to the idea that false vacua in quantum field theory can always decay with some finite rate. I'll explain why the title of the talk makes sense anyway by discussing some simple QFTs which have false vacua which can live an arbitrarily long time. Their lifetime is set by the short-distance details of the theory, rather than the familiar long-distance ingridients discussed in textbook presentations of false-vacuum decay. The talk will focus on examples in 2d and 4d, with the 4d example having the same propagating degrees of freedom as conventional QCD, and the (near) eternal false vacua will turn out to be consequences of (nearly exact) (d-3)-form global symmetries.

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Lecture / Discussion Thu, 11 Mar 2021 08:32:26 -0500 2021-03-19T12:00:00-04:00 2021-03-19T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Applied Interdisciplinary Mathematics (AIM) Seminar | Probing the Cores of Massive Stars through their Surface (March 19, 2021 3:00pm) https://events.umich.edu/event/82849 82849-21201322@events.umich.edu Event Begins: Friday, March 19, 2021 3:00pm
Location: Off Campus Location
Organized By: Department of Physics

Stars are opaque, which makes it difficult to study their interiors. Recent space-based telescopes have led to the new field of asteroseismology: by measuring global oscillation modes of a star, you can infer its interior properties. Massive stars have convection in their cores which can generate waves, which might be detectable at the surface. In the first part of this talk, I will describe a heuristic way of estimating wave generation by convection, and compare it to high-resolution numerical simulations in Cartesian geometry. To make quantitative predictions to compare with observations, one must run simulations in spherical geometry. In the second part of my talk, I will present a new spectral algorithm for solving nearly arbitrary, tensorial PDEs in spherical coordinates. The challenge is to devise bases which respect regularity conditions at r=0, which depend on the rank of the tensor. The algorithm can be easily applied to the problem of wave generation by convection in stars, as well as a wide range of other problems in stellar astrophysics, core geophysics, and planetary sciences.

Please contact Charlie Doering (doering@umich.edu) with any questions.

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Workshop / Seminar Mon, 08 Mar 2021 11:52:03 -0500 2021-03-19T15:00:00-04:00 2021-03-19T16:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Saturday Morning Physics VIRTUAL Event | From Milkmaids to mRNA (March 20, 2021 10:30am) https://events.umich.edu/event/82125 82125-21036720@events.umich.edu Event Begins: Saturday, March 20, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

Dr. Fuller will give a pre-recorded Lecture and a Live Q&A.
Virtual Presentation Link: https://www.youtube.com/watch?v=5mN-qJmWRkI (Link will be active at 10:30 am on 03/20/21.)

The discovery that host immune defenses could be primed, a process called immunization or vaccination, helped to eradicate smallpox. Immunization has changed the global impacts of infectious diseases. Messenger RNA (mRNA) vaccines that have Emergency Use Authorization are one part of the toolkit for managing COVID-19. What is mRNA anyway? We will explore connections among mRNA, milkmaids and microbial pathogens.

We celebrate the James Robert Walker Lecture on this occasion.

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Lecture / Discussion Mon, 15 Mar 2021 08:46:12 -0400 2021-03-20T10:30:00-04:00 2021-03-20T11:30:00-04:00 Off Campus Location Saturday Morning Physics Lecture / Discussion Image of Dr. Oveta Fuller
HEP-Astro Seminar | Understanding the Limitations and Evolution of Black Hole Feedback in Massive Galaxies (March 22, 2021 4:00pm) https://events.umich.edu/event/82494 82494-21110100@events.umich.edu Event Begins: Monday, March 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Energetic feedback from supermassive black holes is thought to be responsible for preventing star formation in massive galaxies, including our own Milky Way. The most massive galaxies in the Universe, which live at the centers of galaxy clusters, provide a unique, "high-contrast" opportunity to study the details of this feedback. I will present a summary of work from our group studying the limitations and details of black hole feedback in massive galaxies, the evolution of the cooling/feedback balance over ~10 Gyr, and what we have learned about lower-mass galaxies by studying these most-massive systems. I will finish with a summary of other cluster research, and a look ahead to the future of research in this field.

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Workshop / Seminar Mon, 22 Mar 2021 18:15:29 -0400 2021-03-22T16:00:00-04:00 2021-03-22T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Todd Barber on the Curiosity Rover (March 23, 2021 8:00pm) https://events.umich.edu/event/83025 83025-21253076@events.umich.edu Event Begins: Tuesday, March 23, 2021 8:00pm
Location: Off Campus Location
Organized By: American Institute of Aeronautics and Astronautics

Curiosity's mission to the red planet will be covered in detail by Todd Barber, a graduate of MIT and recipient of NASA's exceptional achievement award. Topics to be discussed include the history of Mars rovers at JPL, the scientific motivation for Curiosity, and the preparations for launch two days after Thanksgiving in 2011.

The science suite on board this one-ton mega rover will be presented, as well as the engineering challenges involved in getting Curiosity to the launch pad, traveling 352 million miles to Mars over 8.5 months, and ‘sticking the landing’ following the so-called ‘seven minutes of terror’ on August 5th, 2012.

Please join AIAA virtually for this event with an amazing speaker!

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Lecture / Discussion Sun, 14 Mar 2021 21:43:32 -0400 2021-03-23T20:00:00-04:00 2021-03-23T21:15:00-04:00 Off Campus Location American Institute of Aeronautics and Astronautics Lecture / Discussion Flyer
HET Brown Bag Seminar | Freeze-in versus Glaciation: freezing into a thermalized hidden sector (March 24, 2021 12:00pm) https://events.umich.edu/event/82238 82238-21060438@events.umich.edu Event Begins: Wednesday, March 24, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The standard freeze-in paradigm has a hidden UV sensitivity in that the initial DM population is assumed to be exactly zero. We explore how a pre-existing population of DM, either alone or as part of a thermalized dark sector, affects the dynamics of freeze-in. The UV sensitivity of this more general scenario, which we dub “glaciation”, is manifested in the dependence of the late-time relic abundance on the size of the initial population. We dispense rather quickly with the case of a stand-alone initial DM abundance, which simply leads to an offset in the relic abundance compared to the standard scenario, but we find rich and interesting dynamics in the case of a pre-existing thermalized dark sector. Our results have important consequences for direct detection experiments searching for freeze-in dark matter.

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Lecture / Discussion Tue, 30 Mar 2021 12:15:28 -0400 2021-03-24T12:00:00-04:00 2021-03-24T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Department Colloquium CRLT Workshop: Teaching for Equity & Inclusion (March 24, 2021 3:30pm) https://events.umich.edu/event/82671 82671-21155685@events.umich.edu Event Begins: Wednesday, March 24, 2021 3:30pm
Location: Off Campus Location
Organized By: Department Colloquia

This workshop will be interactive and will focus on teaching for equity and inclusion.

How can instructors deliberately cultivate learning environments where all students feel valued, respected, and supported in their learning? This interactive synchronous session will provide structured opportunities for instructors to reflect on their goals and practices related to inclusion and equity, consider how to apply key research-based inclusive teaching principles to their f2f and remote teaching, and exchange ideas with colleagues to support the deliberate cultivation of inclusive learning environments.

We highly encourage anyone who is in or plans to be in a teaching role to participate in the workshop. Alongside faculty members, this includes postdocs and graduate students.

A Zoom link for the workshop will be added closer to the event date.

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Workshop / Seminar Tue, 02 Mar 2021 12:43:48 -0500 2021-03-24T15:30:00-04:00 2021-03-24T17:00:00-04:00 Off Campus Location Department Colloquia Workshop / Seminar
CCMB / DCMB Weekly Seminar Series Featuring Duncan K. Ralph (Fred Hutchinson Cancer Research Center) (March 24, 2021 4:00pm) https://events.umich.edu/event/82733 82733-21169592@events.umich.edu Event Begins: Wednesday, March 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Antibodies are an integral part of the adaptive immune response, and are a critical component of both vaccine-induced and naturally-acquired immunity. The development of deep sequencing approaches in recent years has allowed us to sample a significant fraction of the diverse repertoire of B cell receptor sequences from which antibodies are made. These sequences encode a wealth of information on the somatic rearrangement and evolutionary processes that determine the contours of our antibody repertoires, and thus our ability to respond appropriately to pathogens and vaccines. Extracting this information, however, requires a careful inference approach across several different analysis steps. I will describe the computational approaches that we have taken to solving these problems, which constitute the partis software package, and describe their application in several projects, including HIV and Dengue data.

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Biography: Duncan attended the University of California at Santa Cruz for his undergraduate studies in physics, completing his thesis on energy transport in condensed matter theory in 2005. He completed his PhD at the Massachusetts Institute of Technology in 2014, working on the Large Hadron Collider at the European particle physics laboratory (CERN). His thesis described the observation of Higgs boson decays to four leptons. Since 2014, he has worked in Frederick Matsen’s lab at the Fred Hutchinson Cancer Research Center, first as a postdoctoral researcher and more recently as a staff scientist, writing new computational methods for the analysis of B cell receptor deep sequencing data.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 04 Mar 2021 11:20:24 -0500 2021-03-24T16:00:00-04:00 2021-03-24T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
5th Annual RNA Symposium, "Processing RNA" (March 25, 2021 11:00am) https://events.umich.edu/event/80161 80161-20572609@events.umich.edu Event Begins: Thursday, March 25, 2021 11:00am
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

FOR MORE DETAILS & ABSTRACTS VISIT: https://rna.umich.edu/2021-symposium/

Thursday, March 25, 2021
11:00 / Welcome
11:05 / KEYNOTE 1: Tracy Johnson, UCLA, “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression”
12:00 / Short break
12:10 / KEYNOTE 2: Kevin Weeks, UNC, “Structure-Based Discovery of New Functions in Large RNAs”
1:05 / Data Blitz: Cathy Smith, Daniel Peltier, Yan Zhang
1:35 / KEYNOTE 3: Feng Zhang, MIT, “Exploration of Biological Diversity to Discover Novel Molecular Technologies”
2:30 / Close Day 1

Friday, March 26, 2021
11:00 / Welcome
11:05 / KEYNOTE 4: Brenda Bass, University of Utah, “Distinguishing self and non-self dsRNA in vertebrates and invertebrates”
12:00 / Short break
12:10 / KEYNOTE 5: Christopher Lima, Sloan-Kettering Institute, “Mechanisms that target RNA for destruction”
1:05 / Data Blitz: Meredith Purchal, Adrien Chauvier, Shannon Wright
1:35 / Panel discussion with keynote speakers
2:30 / Close Day 2

Liveblogging by MiSciWriters! https://misciwriters.com/

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Lecture / Discussion Tue, 23 Mar 2021 15:03:26 -0400 2021-03-25T11:00:00-04:00 2021-03-25T14:30:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion 5th Annual RNA Symposium
5th Annual RNA Symposium, "Processing RNA" (March 26, 2021 11:00am) https://events.umich.edu/event/80161 80161-20572610@events.umich.edu Event Begins: Friday, March 26, 2021 11:00am
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

FOR MORE DETAILS & ABSTRACTS VISIT: https://rna.umich.edu/2021-symposium/

Thursday, March 25, 2021
11:00 / Welcome
11:05 / KEYNOTE 1: Tracy Johnson, UCLA, “RNA Splicing, Chromatin Modification, and the Coordinated Control of Gene expression”
12:00 / Short break
12:10 / KEYNOTE 2: Kevin Weeks, UNC, “Structure-Based Discovery of New Functions in Large RNAs”
1:05 / Data Blitz: Cathy Smith, Daniel Peltier, Yan Zhang
1:35 / KEYNOTE 3: Feng Zhang, MIT, “Exploration of Biological Diversity to Discover Novel Molecular Technologies”
2:30 / Close Day 1

Friday, March 26, 2021
11:00 / Welcome
11:05 / KEYNOTE 4: Brenda Bass, University of Utah, “Distinguishing self and non-self dsRNA in vertebrates and invertebrates”
12:00 / Short break
12:10 / KEYNOTE 5: Christopher Lima, Sloan-Kettering Institute, “Mechanisms that target RNA for destruction”
1:05 / Data Blitz: Meredith Purchal, Adrien Chauvier, Shannon Wright
1:35 / Panel discussion with keynote speakers
2:30 / Close Day 2

Liveblogging by MiSciWriters! https://misciwriters.com/

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Lecture / Discussion Tue, 23 Mar 2021 15:03:26 -0400 2021-03-26T11:00:00-04:00 2021-03-26T14:30:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion 5th Annual RNA Symposium
"RNA boogie: Structural Dynamics by NMR" (March 26, 2021 12:00pm) https://events.umich.edu/event/83217 83217-21314485@events.umich.edu Event Begins: Friday, March 26, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

ABSTRACT: Many functions of RNA depend on rearrangements in secondary structure that are triggered by external factors, such as protein or small molecule binding. These transitions can feature on one hand localized structural changes in base-pairs or can be presented by a change in chemical identity of e.g. a nucleo-base tautomer. We use and develop R1ρ-relaxation-dispersion NMR methods for characterizing transient structures of RNA that exist in low abundance (populations <10%) and that are sampled on timescales spanning three orders of magnitude (µs to s).
The characterization of three different types of transient structures is going to be presented. 1) The HIV-1 dimerization initiation site (DIS) undergoes large secondary structure rearrangements that provide the basis for a molecular zipper, which can be crucial for genome packaging (Nature 2012). 2) The GU wobble base-pair undergoes a change from standard wobble GU geometry to appear like a Watson-Crick base-pair stabilized by Keto-Enol tautomerization (Nature 2015). 3) a microRNA – mRNA complex changes conformation to activate the RISC complex (Nature 2020). I will furthermore give an outlook on recent efforts to measure in-cell NMR of nucleic acids in functional complexes. www.petzoldlab.com

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Livestream / Virtual Mon, 22 Mar 2021 23:09:51 -0400 2021-03-26T12:00:00-04:00 2021-03-26T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual Katja Petzold
HEP-Astro Seminar | Modeling Binary Black Holes With Numerical Relativity in the Era of Gravitational-Wave Observations (March 29, 2021 4:00pm) https://events.umich.edu/event/82106 82106-21036679@events.umich.edu Event Begins: Monday, March 29, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

The era of gravitational-wave astronomy began in 2015 with LIGO's discovery of gravitational waves from merging black holes in 2015. Since then, LIGO and Virgo have observed dozens of gravitational waves merging black holes and neutron stars; accurate models of these waves are crucial for learning as much as possible about the waves’ astronomical sources. Models of binary black holes require numerical relativity, because all analytic approximations fail near the time of merger. While these models are sufficiently accurate for today’s observatories, avoiding bias in interpreting the waves observed by next-generation observatories on Earth and in space will require next-generation numerical relativity models. In this talk, I will present some recent results in modeling observations of binary black holes withnumerical relativity, and I will discuss progress toward simulating merging black holes with SpECTRE, a next-generation numerical relativity code under development by the Simulating eXtreme Spacetimes collaboration.

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Workshop / Seminar Mon, 29 Mar 2021 18:15:25 -0400 2021-03-29T16:00:00-04:00 2021-03-29T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
CM-AMO Seminar | Non-Equilibrium Control of Quantum Materials: Engineering Crystal Structures With Light (March 30, 2021 4:00pm) https://events.umich.edu/event/83078 83078-21266960@events.umich.edu Event Begins: Tuesday, March 30, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

Quantum materials exhibit unique macroscopic phenomena with enormous technological potential, ranging from high-temperature superconductivity to topologically protected transport. Hence, at the forefront of condensed matter research is the goal of understanding and controlling their emergent behavior at the smallest length and time scales possible. Due to the strongly intertwined nature of electrons and the crystal lattice in these materials, manipulating the atomic structure allows one to tune interactions and create novel electronic and magnetic phases.

In this talk, I will describe how light can be used to engineer structural distortions in quantum materials on ultrafast time scales, providing a powerful pathway to realize non-equilibrium states of matter, often with functionalities not accessible statically. First, I will illustrate the application of this approach, based on the resonant excitation of optical phonons and terahertz frequencies, to the antiferromagnet CoF2. By exploiting lattice anharmonicities, a transition to a ferrimagnetic phase could be driven with light, whose magnetization is 100-fold larger than the equilibrium limit. Second, I will demonstrate that the coupling of optically driven phonons to long-wavelength strain leads to a metastable ferroelectricity in the quantum paraelectric SrTiO3, with the symmetry-broken state remaining for up to hours after excitation. These experiments provide a basis for the rational design of non-equilibrium functionalities; integrated with targeted materials synthesis, such control promises to unlock new physical phenomena and enable next-generation quantum and ultrafast technologies.


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Workshop / Seminar Tue, 30 Mar 2021 18:15:29 -0400 2021-03-30T16:00:00-04:00 2021-03-30T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
CCMB / DCMB Weekly Seminar (March 31, 2021 4:00pm) https://events.umich.edu/event/83395 83395-21369780@events.umich.edu Event Begins: Wednesday, March 31, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Large, deeply phenotyped cohorts are reshaping the world of environmental epidemiology. Two such “big data” resources that are reshaping how we understand environmental health are electronic health records and human cohorts with genome-wide molecular phenotyping. Each provides a unique perspective that is moving the field closer towards “personalized” insights into environmental health risks. Here I will talk about a series of studies which utilize electronic health records and molecularly phenotyped cohorts to investigate vulnerable populations, gene-environment interactions, and epigenetic biomarkers of environmental sensitivity. Together these studies are helping us to understand environmental health risks in a new light.

Short bio:

Dr. Cavin Ward-Caviness is a Principal Investigator in the Public Health and Integrated Toxicology Division of the US Environmental Protection Agency. With a background in computational biology and environmental epidemiology, Dr. Ward-Caviness seeks to understand the environmental factors which influence health in vulnerable populations and the molecular mechanisms that influence environmental health risks. The Ward-Caviness lab uses a variety of “big data” approaches, and Dr. Ward-Caviness is the PI of the EPA CARES research resource, which allows researchers to study environmental health effects in vulnerable patient populations, e.g. individuals with heart failure, using large electronic health record databases. Dr. Ward-Caviness is also interested in how epigenetics and metabolomics can serve as an early indicator of adverse health effects from chemical and social environmental exposures and in particular how molecular biomarkers can give us insight into how the environment may accelerate the aging process and thus contribute to chronic disease. By integrating molecular and clinical data, Dr. Ward-Caviness seeks to understand environmental health as a way to advance personalized medicine and reduce health disparities.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 29 Mar 2021 15:15:11 -0400 2021-03-31T16:00:00-04:00 2021-03-31T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
MCAIM Colloquium - Inference for Circadian Pacemaking (March 31, 2021 4:00pm) https://events.umich.edu/event/83216 83216-21320455@events.umich.edu Event Begins: Wednesday, March 31, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Mathematics

Organisms have evolved an internal biological clock which allows them to temporally regulate and organize their physiological and behavioral responses to cope in an optimal way with the fundamentally periodic nature of the environment. It is now well established that the molecular genetics of such rhythms within the cell consist of interwoven transcriptional-translational feedback loops involving about 15 clock genes, which generate circa 24-h oscillations in many cellular functions at cell population or whole organism levels. We will present statistical methods and modelling approaches that address newly emerging large circadian data sets, namely spatio-temporal gene expression in SCN neurons and rest-activity actigraph data obtained from non-invasive e-monitoring, both of which provide unique opportunities for furthering progress in understanding the synchronicity of circadian pacemaking and address implications for monitoring patients in chronotherapeutic healthcare.

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Livestream / Virtual Tue, 23 Mar 2021 12:36:41 -0400 2021-03-31T16:00:00-04:00 2021-03-31T17:00:00-04:00 Off Campus Location Department of Mathematics Livestream / Virtual Bärbel Finkenstädt Rand, University of Warwick, Department of Statistics
HET Brown Bag Seminar | Twisting with a flip (April 1, 2021 12:00pm) https://events.umich.edu/event/81280 81280-20879918@events.umich.edu Event Begins: Thursday, April 1, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

I will consider N=2 supersymmetric gauge theories on 4D compact manifolds with a Killing vector field with isolated fixed points. Studying the realization of supersymmetry in these theories leads to consider a generalization of the notion of self-duality on manifolds with a vector field. This allows to construct a framework unifying equivariant Donaldson-Witten theory and Pestun's theory on S4 and its generalizations. I will also discuss the action of S-duality in these theories.

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Lecture / Discussion Fri, 26 Mar 2021 14:39:06 -0400 2021-04-01T12:00:00-04:00 2021-04-01T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
The Van Loo Family Saturday Morning Physics VIRTUAL Event | Graduate Student Presentations (April 3, 2021 10:30am) https://events.umich.edu/event/82127 82127-21036722@events.umich.edu Event Begins: Saturday, April 3, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

Pre-recorded lecture followed by “live” Q&A
Virtual Presentation Link: https://www.youtube.com/watch?v=tc340N56GvY

Instruments to Study Rocket Plume Surface Interactions (PSI) on the Lunar Surface
Ariana Bueno (U-M Climate and Space Sciences and Engineering & Applied Physics)
In space exploration, the rocket plume-surface interaction (PSI) can lead to the ejection of large amounts of energetic particles, potentially damaging the spacecraft, its instruments, and associated hardware. Thus, understanding PSI processes is paramount to the safety of the lunar exploration program and beyond. In this presentation, Ariana will highlight how her research has led to a better understanding of PSI by developing in-flight instrumentation and conducting ground tests to simulate PSI.

Histotripsy: Crushing Cancer Cells with Acoustic Cavitation
Ryan Hubbard (U-M Biomedical Engineering & U-M Applied Physics)
Histotripsy is a non-invasive cancer-treatment approach using focused beams of ultrasound. In this presentation, Ryan will highlight the results of his research, illustrating histotripsy's ability to destroy tumor cells and elicit anti-tumor immune responses. He will describe the basics behind ultrasonic pulse generation, acoustic cavitation, and how the mechanism of histotripsy compares to other external beam treatments such as X-ray irradiation.

We celebrate the Van Loo Family Lecture on this occasion.

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Lecture / Discussion Tue, 23 Mar 2021 11:04:35 -0400 2021-04-03T10:30:00-04:00 2021-04-03T11:30:00-04:00 Off Campus Location Saturday Morning Physics Lecture / Discussion
HEP-Astro Seminar | AION: Atom Interferometer Observatory and Network (April 5, 2021 4:00pm) https://events.umich.edu/event/83426 83426-21377656@events.umich.edu Event Begins: Monday, April 5, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

In this seminar I will outline the experimental concept and key scientific capabilities of AION (Atom Interferometer Observatory and Network), a proposed experimental programme using cold strontium atoms to search for ultra-light dark matter, to explore gravitational waves in the mid-frequency range between the peak sensitivities of the LISA and LIGO/Virgo/ KAGRA/INDIGO/Einstein Telescope/Cosmic Explorer experiments, and to probe other frontiers in fundamental physics.

The first stage of the project was recently funded with about £10M and involves leading UK institutions: University of Birmingham, University of Cambridge, Imperial College London (lead institution), Kings College London, University of Liverpool, University of Oxford, and STFC Rutherford Appleton Laboratory The project is also in partnership with UK National Quantum Technology Hub in Sensors and Timing, Birmingham, UK, the MAGIS Collaboration, US and the Fermi National Accelerator Laboratory, US.

AION would complement other planned searches for dark matter, as well as probe mergers involving intermediate-mass black holes and explore early-universe cosmology. AION would share many technical features with the MAGIS experimental programme, and synergies would flow from operating AION in a network with this experiment, as well as with other atom interferometer experiments such as MIGA, ZAIGA and ELGAR. Operating AION in a network with other gravitational wave detectors such as LIGO, Virgo and LISA would also offer many synergies.

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Workshop / Seminar Mon, 05 Apr 2021 18:15:22 -0400 2021-04-05T16:00:00-04:00 2021-04-05T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Physics Grad Council and SPS Special Workshop | International Student Advocacy Workshop (April 7, 2021 3:30pm) https://events.umich.edu/event/83486 83486-21391450@events.umich.edu Event Begins: Wednesday, April 7, 2021 3:30pm
Location: Off Campus Location
Organized By: Department of Physics

Physics Grad Council and the Society of Women in Physics would like to invite you all to a workshop on International Student Advocacy. We will have graduate students joining us to share their experiences, and have also invited David Cole from the International Center to tell us more about various aspects of navigating the US as an international student.

This workshop is aimed at both international students who want to share their experiences or gain advice from other grad students, as well as the rest of our community, to come and learn more about the issues that international students face and the ways they navigate being a student and a community member. We hope to encourage communication and uncover ways we can be better allies to each other.

Please RSVP to the following link if you're interested in attending our workshop: https://myumi.ch/ovld9.

By registering here, you can sign up to receive reminders before the workshop and can receive copies of the slides and other resources we use. This link also contains our zoom information.

Also: If you are an international student, please consider filling out our survey, so that we can better tailor our material to everyone's needs: https://forms.gle/6QX33aFtFYc7vKYm6

We look forward to seeing you online!

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Workshop / Seminar Thu, 01 Apr 2021 10:15:31 -0400 2021-04-07T15:30:00-04:00 2021-04-07T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
CCMB / DCMB Weekly Seminar Series (April 7, 2021 4:00pm) https://events.umich.edu/event/83241 83241-21320453@events.umich.edu Event Begins: Wednesday, April 7, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: More than 3,000 new Marine recruits were studied prospectively during their initial Marine-mandated two-week quarantine and their subsequent basic training at Parris Island. The COVID Health Action Response for Marines (CHARM) studied completed 20,000 study visits and obtained more than 70,000 biosamples including pre- to post- SARS-CoV-2 infections in more than 1000 recruits. Serological, transcriptomic, and epigenetic analyses identify the response signature to SARS-CoV-2 infection in these largely asymptomatic young adults. Phylogenetic analysis and modeling provide insight into epidemiology and guidance for public health measures.

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Specialty: Neurology

Research Topics: Addiction, Apoptosis/Cell Death, Basal Ganglia, Bioinformatics, Brain, Cellular Immunity, Cerebral Cortex, Mathematical and Computational Biology, Multiple Sclerosis, Neuro-degeneration/protection, Receptors, Reproductive Biology, Signal Transduction, Theoretical Biology, Vaccine Development, Viruses and Virology

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 23 Mar 2021 11:23:58 -0400 2021-04-07T16:00:00-04:00 2021-04-07T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
MCAIM Colloquium - Deep Neural Networks for High-dimensional Uncertain Decision Problems (April 7, 2021 4:00pm) https://events.umich.edu/event/83243 83243-21322430@events.umich.edu Event Begins: Wednesday, April 7, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Mathematics

Stochastic optimal control has been an effective tool for many decision problems. Although, they provide the much needed quantitative modeling for such problems, until recently they have been numerically intractable in high-dimensional settings. However, several recent studies that use deep neural networks report impressive numerical results in high dimensions when the structure of the uncertainty is assumed to be known. The main tool is a Monte-Carlo type algorithm combined with deep neural networks proposed by Han, E and Jentzen. In this talk, I will outline this approach and discuss its properties; in particular, the difficulties that data-driven problems face as opposed to model-driven ones. Numerical results, while validating the power of the method in high dimensions, they also show the dependence on the dimension and the size of the training data. This is joint work with Max Reppen of Boston University.

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Livestream / Virtual Tue, 23 Mar 2021 12:31:39 -0400 2021-04-07T16:00:00-04:00 2021-04-07T17:00:00-04:00 Off Campus Location Department of Mathematics Livestream / Virtual Mete Soner Institution, Princeton University, Department of Operations Research and Financial Engineering
HET Brown Bag Seminar | Geometric constraints on the space of 4d theories (April 8, 2021 12:00pm) https://events.umich.edu/event/83263 83263-21328373@events.umich.edu Event Begins: Thursday, April 8, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The geometry of the moduli space of four dimensional superconformal theories is uniquely constrained by complex geometry and it thus represents an ideal set up for a bottom up classification program. I will describe these peculiar features, provide an update on a series of new exciting results and outline a variety of open questions.

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Lecture / Discussion Thu, 01 Apr 2021 19:21:46 -0400 2021-04-08T12:00:00-04:00 2021-04-08T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HET Seminar | A Model of Couplings (April 9, 2021 3:00pm) https://events.umich.edu/event/83001 83001-21330359@events.umich.edu Event Begins: Friday, April 9, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Seminar link:http://myumi.ch/O4P7E

String theory predicts that the couplings of Nature descend from dynamical fields. All known string-motivated particle physics models also come with a wide range of possible extra sectors. It is common to posit that such moduli are frozen to a background value, and that extra sectors can be nearly completely decoupled. In this talk we show that performing a partial trace over all sectors other than the visible sector generically puts the visible sector in a mixed state, with coupling constants drawn from a quantum statistical ensemble. An observable consequence of this entanglement between visible and extra sectors is that the reported values of couplings will appear to have an irreducible variance. There is a consequent interplay between energy range and precision of an experiment that allows an extended reach for new physics.

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Lecture / Discussion Wed, 31 Mar 2021 20:41:44 -0400 2021-04-09T15:00:00-04:00 2021-04-09T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | Top Quark Production With Heavy Bosons (April 12, 2021 4:00pm) https://events.umich.edu/event/83468 83468-21385560@events.umich.edu Event Begins: Monday, April 12, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Please contact Beth Demkowski, demkowsk@umich.edu for Zoom link.

The Large Hadron Collider (LHC) is the worlds highest energy particle accelerator. With intense proton beams colliding at very high energies and high rates, the LHC is effectively a “top quark factory” that allows for the precise measurement of properties of the top quark. With the large LHC data, now it is also possible to measure rare processes involving top-quarks. Processes like top anti-top pair production along with other particles, for example Higgs boson or the electroweak force carriers W/Z has been observed at the LHC. Precise measurement of these processes have implications on the Standard Model of particle physics and even in cosmology. Recent results from the measurement of these rare top quark processes will be discussed in this talk.

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Workshop / Seminar Mon, 12 Apr 2021 18:15:18 -0400 2021-04-12T16:00:00-04:00 2021-04-12T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HET Brown Bag Seminar | Dark photons and the cosmic radiation background (April 14, 2021 12:00pm) https://events.umich.edu/event/82059 82059-21014663@events.umich.edu Event Begins: Wednesday, April 14, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The dark photon is a well-motivated extension of the Standard Model which can mix with the regular photon. This mixing is enhanced whenever the dark photon mass matches the primordial plasma frequency, leading to resonant conversions between photons and dark photons. These conversions can produce observable cosmological signatures, including distortions to the cosmic radiation background. In this talk, I will discuss a new analytic formalism for these conversions that can account for the inhomogeneous distribution of matter in our universe, leading to new and revised limits on the mixing parameter of light dark photons derived from the COBE/FIRAS measurement of the cosmic microwave background spectrum. I will then describe some ongoing work on a dark sector model that can explain the longstanding ARCADE radio background excess through resonant conversions of dark photons.

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Lecture / Discussion Thu, 22 Jul 2021 10:32:35 -0400 2021-04-14T12:00:00-04:00 2021-04-14T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
CCMB / DCMB Weekly Seminar (April 14, 2021 4:00pm) https://events.umich.edu/event/83595 83595-21436485@events.umich.edu Event Begins: Wednesday, April 14, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
My lab's research involves the development and application of systems biology approaches—combining computation, machine learning, quantitative modeling, and experiments—to study the immune system in health and disease. Recent technological and computational advances allow comprehensive interrogation of multiple modalities (e.g., proteins, mRNAs, immune receptor sequences) in single cell resolution in the human population. Here I will highlight our work in the analysis human and single cell variations along the axes of early immune development, vaccination, and COVID-19. If time permits, I will also discuss the integration of tissue imaging, machine learning, and multiscale dynamical modeling of immune cell interactions to investigate the homeostatic regulation of autoreactive T cells.

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Biography: Dr. Tsang is a senior investigator in the NIH Intramural Research Program and leads a laboratory focusing on systems and quantitative immunology at the National Institute of Allergy and Infectious Diseases (NIAID). He also co-directs the Trans-NIH Center for Human Immunology (CHI) and leads its research program in systems human immunology. Dr. Tsang trained in computer engineering and computer science at the University of Waterloo and received his Ph.D. in biophysics from Harvard University. Dr. Tsang has worked as a software engineer and pursued systems biology research in both academia and industry including Rosetta Inpharmatics, Caprion Proteomics, MIT, and Merck Research Laboratories. Dr. Tsang has won several awards for his research, including NIAID Merit Awards for the development of a data reuse and crowdsourcing platform OMiCC and for leading a system biology study of human immune variability and influenza vaccination, which was selected as a top NIAID Research Advances of 2014. He currently serves as the founding chief editor of systems immunology for Frontiers in Immunology. He has served as a scientific advisor for a number of programs and organizations including ImmPort (the clinical and molecular data repository for NIAID), the Committee on Precision Medicine for the World Allergy Organization, the NIAID Modeling Immunity for Biodefense Program, the Allen Institute, the Immuno-Epidemiology Program at the National Cancer Institute, and the Human Vaccines Project.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 07 Apr 2021 08:59:05 -0400 2021-04-14T16:00:00-04:00 2021-04-14T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Department Colloquium | The First Measurement of the Muon Anomalous Magnetic Moment from the Fermilab Muon g-2 Collaboration (April 14, 2021 4:00pm) https://events.umich.edu/event/83247 83247-21322432@events.umich.edu Event Begins: Wednesday, April 14, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Link: http://myumi.ch/GkgBm

This colloquium will cover the physics and methods behind Fermilab's Muon g-2 experiment, along with the long-awaited results from Run-1. The experiment was undertaken to resolve the tension between the Standard Model and the previous measurement taken at Brookhaven National Labs. The measured value of the muon anomalous magnetic moment is $a_\mu(FNAL) = 116592040(54)×10^{−11}$. This result is in good agreement with Brookhaven's previous measurement. The new world average, $a_\mu(Exp) = 116592061(41)×10^{−11}$, shows a difference from the theoretical value, $a_\mu(Exp) = 116591810(43)×10^{−11}$, of 4.2 standard deviations, strongly hinting at physics beyond the Standard Model. The experiment requires the simultaneous measurement of the muon precession frequency, the magnetic field, and the muons' distribution in the field. All three of these measurements will be discussed in context, along with the main systematic corrections and uncertainties.

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Workshop / Seminar Wed, 14 Apr 2021 18:15:20 -0400 2021-04-14T16:00:00-04:00 2021-04-14T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
MCAIM Colloquium - Black Hole Imaging: First Results and Future Vision (April 14, 2021 4:00pm) https://events.umich.edu/event/83245 83245-21322433@events.umich.edu Event Begins: Wednesday, April 14, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

In April 2017, the Event Horizon Telescope (EHT) carried out a global Very Long Baseline Interferometry (VLBI) observing campaign at a wavelength of 1mm that led to the first resolved image of a supermassive black hole. For the 6.5 billion solar mass black hole in the giant elliptical galaxy M87, the EHT estimated the spin orientation and constrained models of accretion on Schwarzschild radius scales. This work relied on two decades of technical advances in ultra-high resolution interferometry and theoretical General Relativistic Magnetohydrodynamic (GRMHD) simulations. This talk will review these advances and recent new EHT results. We will also look to the next decade when a next-generation EHT (ngEHT) that doubles the number of participating radio dishes in the VLBI network will enable time-lapse movies of M87 that link the black hole to the relativistic jet it powers. For SgrA*, the Galactic Center black hole that evolves on time scales 1000 times faster, ngEHT will produce real-time video.

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Livestream / Virtual Tue, 23 Mar 2021 12:21:52 -0400 2021-04-14T16:00:00-04:00 2021-04-14T17:00:00-04:00 Off Campus Location Michigan Center for Applied and Interdisciplinary Mathematics Livestream / Virtual Sheperd S. Doeleman, Founding Director of the Event Horizon Telescope, Harvard University, Center for Astrophysics, Harvard and Smithsonian, Black Hole Initiative
Life After Graduate School Seminar | I Did Not See That Coming: My Career as a Random Walk (April 16, 2021 12:00pm) https://events.umich.edu/event/83212 83212-21314481@events.umich.edu Event Begins: Friday, April 16, 2021 12:00pm
Location: Off Campus Location
Organized By: Life After Grad School Seminars

Your graduate degree may seem your greatest achievement. Congratulations. But now may be the time for something totally different. That basically describes my 46-year succession of careers: physics professor, management consultant, statistical taxation consultant, bank operations consultant, engineering information systems manager, security systems developer, public health official, entrepreneur, and corporate executive. Each transition got easier, less threatening, and more rewarding. That seemingly divergent list of positions grew directly out of my physics graduate school experience. Physics is everywhere and a Michigan Ph.D. in physics will open many doors you did not know were there. But you may have a lot of post-doctoral learning to do. Much of that learning will be about yourself. Perhaps I can be of assistance.

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Workshop / Seminar Wed, 31 Mar 2021 11:07:04 -0400 2021-04-16T12:00:00-04:00 2021-04-16T13:00:00-04:00 Off Campus Location Life After Grad School Seminars Workshop / Seminar
RNA Seminar featuring: Jailson (Jay) Brito Querido, Ph.D. MRC Laboratory of Molecular Biology, Cambridge, UK (April 19, 2021 4:00pm) https://events.umich.edu/event/81408 81408-20893767@events.umich.edu Event Begins: Monday, April 19, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

REGISTRATION REQUIRED: https://umich.zoom.us/webinar/register/WN_78YYOhIhTbOBy2_JSdM7Wg

ABSTRACT: A key step in translational initiation is the recruitment of the 43S pre-initiation complex (43S PIC) by the cap-binding complex (eIF4F) at the 5´ end of mRNA. Eukaryotic initiation factors eIF1, eIF1A, eIF3, eIF5, and the ternary complex (TC) of eIF2–GTP–tRNAiMet bind to the 40S ribosomal subunit to form the 43S PIC. Once assembled, the 43S PIC is recruited to the cap-binding complex eIF4F at the 5´end of mRNA to form a 48S initiation complex (48S). The 48S then scans along the mRNA to locate a start codon. To understand the mechanisms involved, we determined the structure of a reconstituted human 48S using cryo-electron microscopy. The structure reveals insights into early events of translation initiation complex assembly. It reveals how eIF4F interacts with subunits of the eIF3 structural core near the mRNA exit channel in the 43S. The location of eIF4F is consistent with a slotting model of mRNA recruitment and suggests a “blind-region” that would preclude recognition of start sites upstream of the location of the P site at the point of recruitment.

KEYWORDS: mRNA, ribosome, eIF4F, eIF4A, translation

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Lecture / Discussion Tue, 13 Apr 2021 12:58:40 -0400 2021-04-19T16:00:00-04:00 2021-04-19T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Jailson (Jay) Brito Querido, Ph.D.
HET Brown Bag Seminar | On 1D, N = 4 Supersymmetric SYK-Type Models (April 22, 2021 12:00pm) https://events.umich.edu/event/83423 83423-21375696@events.umich.edu Event Begins: Thursday, April 22, 2021 12:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

Proposals are made to describe 1D, N = 4 supersymmetrical systems that extend SYK models by compactifying from 4D, N = 1 supersymmetric Lagrangians involving chiral, vector, and tensor supermultiplets. Quartic fermionic vertices are generated via intergrals over the whole superspace, while 2(q-1)-point fermionic vertices are generated via superpotentials. The coupling constants in the superfield Lagrangians are arbitrary, and can be chosen to be Gaussian random. In that case, these 1D, N = 4 supersymmetric SYK models would exhibit Wishart-Laguerre randomness, which share the same feature among other 1D supersymmetric SYK models in literature. One difference with 1D, N = 1 and N = 2 models though, is our models contain dynamical bosons, but this is consistent with other 1D, N = 4 and 2D, N = 2 models in literature.

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Lecture / Discussion Fri, 16 Apr 2021 12:24:45 -0400 2021-04-22T12:00:00-04:00 2021-04-22T13:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Special Joint Seminar between DCMB, Mathematics, MIDAS, and Smale Institute (April 22, 2021 1:00pm) https://events.umich.edu/event/83615 83615-21491327@events.umich.edu Event Begins: Thursday, April 22, 2021 1:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

The quest to understand consciousness, once the purview of philosophers and theologians, is now actively pursued by scientists of many stripes. This talk looks at consciousness from the perspective of theoretical computer science. It formalizes the Global Workspace Theory (GWT) originated by cognitive neuroscientist Bernard Baars and further developed by him, Stanislas Dehaene, and others. Our major contribution lies in the precise formal definition of a Conscious Turing Machine (CTM), also called a Conscious AI. We define the CTM in the spirit of Alan Turing’s simple yet powerful definition of a computer, the Turing Machine (TM). We are not looking for a complex model of the brain nor of cognition but for a simple model of (the admittedly complex concept of) consciousness. After formally defining CTM, we give a formal definition of consciousness in CTM. We then suggest why the CTM has the feeling of consciousness. The reasonableness of the definitions and explanations can be judged by how well they agree with commonly accepted intuitive concepts of human consciousness, the range of related concepts that the model explains easily and naturally, and the extent of its agreement with scientific evidence.

https://umich.zoom.us/j/95135773568

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Livestream / Virtual Wed, 14 Apr 2021 10:17:45 -0400 2021-04-22T13:00:00-04:00 2021-04-22T14:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
CGIS Winter Advising (May 19, 2021 12:00pm) https://events.umich.edu/event/83938 83938-21619171@events.umich.edu Event Begins: Wednesday, May 19, 2021 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

As studying abroad becomes more of a possibility for U-M students, particularly for Winter 2022, CGIS will be offering a 2-day Winter Advising event where students can learn more about major-specific programs such as programs in the environment, pre-health, and public health and interest-specific program sessions such as studying abroad in the UK and English-Taught programs in Asia to name few. The LSA Scholarship Office and the Office of Financial Aid will join us on May 20th to help answer questions you may have on funding your semester program abroad as well as walking you through the application process! First Step sessions will be offered each day of the event as well. Each info session will be interactive. Each session will offer an opportunity to interact with advisors and address questions or concerns you may have regarding study abroad. To get a general idea of participation, please RSVP below and select info sessions that you'd be interested in. We'll send you a Zoom link as we get closer to the event!

DISCLAIMER: With each passing term, a small yet increasing number of our programs seem to offer the possibility of receiving students, so CGIS proceeded with very cautious optimism that students will be able to study abroad in the coming academic year. CGIS and the University of Michigan continue to closely monitor the COVID-19 (Coronavirus) situation as it develops worldwide. Parents and other concerned parties who would like to receive this information should ask their students to share the updates with them. Students planning to participate in CGIS programs worldwide are advised to continue to closely monitor the latest developments and to adhere to any national and international public health directives issued by their host country or institution. CGIS will contact students who have opened or submitted an application to a CGIS program if and when updates are available.

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Presentation Fri, 30 Apr 2021 16:02:10 -0400 2021-05-19T12:00:00-04:00 2021-05-19T14:30:00-04:00 Off Campus Location Center for Global and Intercultural Study Presentation Flyer
CGIS Winter Advising (May 20, 2021 12:00pm) https://events.umich.edu/event/83938 83938-21619172@events.umich.edu Event Begins: Thursday, May 20, 2021 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

As studying abroad becomes more of a possibility for U-M students, particularly for Winter 2022, CGIS will be offering a 2-day Winter Advising event where students can learn more about major-specific programs such as programs in the environment, pre-health, and public health and interest-specific program sessions such as studying abroad in the UK and English-Taught programs in Asia to name few. The LSA Scholarship Office and the Office of Financial Aid will join us on May 20th to help answer questions you may have on funding your semester program abroad as well as walking you through the application process! First Step sessions will be offered each day of the event as well. Each info session will be interactive. Each session will offer an opportunity to interact with advisors and address questions or concerns you may have regarding study abroad. To get a general idea of participation, please RSVP below and select info sessions that you'd be interested in. We'll send you a Zoom link as we get closer to the event!

DISCLAIMER: With each passing term, a small yet increasing number of our programs seem to offer the possibility of receiving students, so CGIS proceeded with very cautious optimism that students will be able to study abroad in the coming academic year. CGIS and the University of Michigan continue to closely monitor the COVID-19 (Coronavirus) situation as it develops worldwide. Parents and other concerned parties who would like to receive this information should ask their students to share the updates with them. Students planning to participate in CGIS programs worldwide are advised to continue to closely monitor the latest developments and to adhere to any national and international public health directives issued by their host country or institution. CGIS will contact students who have opened or submitted an application to a CGIS program if and when updates are available.

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Presentation Fri, 30 Apr 2021 16:02:10 -0400 2021-05-20T12:00:00-04:00 2021-05-20T14:30:00-04:00 Off Campus Location Center for Global and Intercultural Study Presentation Flyer
Time-Resolved Vibrational Spectroscopy Meeting (June 13, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620694@events.umich.edu Event Begins: Sunday, June 13, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-13T09:00:00-04:00 2021-06-13T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
Time-Resolved Vibrational Spectroscopy Meeting (June 14, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620695@events.umich.edu Event Begins: Monday, June 14, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-14T09:00:00-04:00 2021-06-14T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
Time-Resolved Vibrational Spectroscopy Meeting (June 15, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620696@events.umich.edu Event Begins: Tuesday, June 15, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-15T09:00:00-04:00 2021-06-15T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
Time-Resolved Vibrational Spectroscopy Meeting (June 16, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620697@events.umich.edu Event Begins: Wednesday, June 16, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-16T09:00:00-04:00 2021-06-16T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
Time-Resolved Vibrational Spectroscopy Meeting (June 17, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620698@events.umich.edu Event Begins: Thursday, June 17, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-17T09:00:00-04:00 2021-06-17T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
Time-Resolved Vibrational Spectroscopy Meeting (June 18, 2021 9:00am) https://events.umich.edu/event/84177 84177-21620699@events.umich.edu Event Begins: Friday, June 18, 2021 9:00am
Location: Off Campus Location
Organized By: Physics Workshops & Conferences

For more than 30 years, the International Conference on Time-Resolved Vibrational Spectroscopy (TRVS) has played a central role in highlighting state-of-the-art progress in understanding, manipulating, and driving vibrations in molecular and material dynamics.

TRVS 2021 (June 13-18) will bring researchers from around the world together to discuss the following topics:

• Dynamics of liquids, solids, interfaces, and nanostructured materials

• Role of vibrational dynamics in electronically excited molecules and materials

• Chemical, vibrational, and hydrogen bonding dynamics

• Time-resolved vibrational spectroscopy in molecular biophysics and photobiology

• Proton and electron transfer studies for energy conversion and storage

• Advances in multi-dimensional vibrational spectroscopy: Infrared, Raman, and THz

• New laser sources and spectrometers

• Single molecule vibrational spectroscopy

• Theoretical and computational spectroscopy

Please see https://www.trvs2021.org/ for more information and to register.

Hosts: U-M Physicist Jennifer Ogilvie and research team along with U-M Chemist Kevin Kubyarch.

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Workshop / Seminar Wed, 02 Jun 2021 11:01:41 -0400 2021-06-18T09:00:00-04:00 2021-06-18T17:00:00-04:00 Off Campus Location Physics Workshops & Conferences Workshop / Seminar
CM-AMO Seminar | A Series of Three Lectures on: Floquet states, Rabi oscillations, Fermi's golden rule and all that (Lecture 1 of 3) (August 31, 2021 4:00pm) https://events.umich.edu/event/85767 85767-21628808@events.umich.edu Event Begins: Tuesday, August 31, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Rabi oscillations arise when a few-level quantum system is subjected to a periodically time-varying field while Floquet states are stationary solutions of a quantum system in the presence of a periodic time-dependent perturbation. Past the simplest derivations, students interested in these topics may miss to grasp the connection between Rabi oscillations and Floquet states beyond the obvious fact that they both involve a time-varying field. Equally important, they may struggle to find pedagogical accounts in the literature discussing the effect of dissipation, which is central to the interpretation of many physical phenomena. They may also ponder about the question as to how Rabi oscillations and Floquet states relate to results of time-dependent perturbation theory, particularly concerning Fermi golden rule and linear response theory. In these series of lectures, aimed at students, we introduce an exactly solvable model of a two-level system coupled to a continuum, which interacts with a sinusoidally time-varying classical field. Results show that the behavior of the two-level system can be mapped onto the problem of a static field, if one shifts the energy separation between the two levels by an amount equal to the frequency of the field. This correspondence allows one to view Rabi oscillations and Floquet states from the different perspective of their time-independent-problem equivalents. The comparison between the rigorous results and those from perturbation theory helps clarify some of the difficulties underlying textbook proofs of Fermi golden rule, and the discussions on quantum decay and linear response theory.

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Workshop / Seminar Tue, 31 Aug 2021 18:16:00 -0400 2021-08-31T16:00:00-04:00 2021-08-31T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Interdisciplinary QC/CM Seminar | Dynamics and Thermodynamics of Single Molecule Junctions: A Green's Function Perspective (September 2, 2021 4:00pm) https://events.umich.edu/event/85036 85036-21625494@events.umich.edu Event Begins: Thursday, September 2, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Nonlinear optical spectroscopy has been developed and widely utilized as control and characterization tool in studies of optical response of molecules. Similarly, nonadiabatic molecular dynamics is a fundamental problem related to breakdown of timescale separation between electron and nuclear dynamics. It plays an important role in many processes from chemistry and photochemistry to spectroscopy and non-radiative electronic relaxation and from electron and proton transfer to coherent control and photo induced energy transfer. Theoretical studies of energy storage and conversion usually rely on macroscopic thermodynamic formulation.

The progress of experimental techniques at the nanoscale made measurements of responses of single molecule junctions a reality. Proper description of such open nonequilibrium systems is a challenging theoretical problem. For example, optical spectroscopy of open nonequilibrium systems is a natural meeting point for at least two research areas: nonlinear optical spectroscopy and quantum transport; while proper description of performance of nanoscale devices for energy conversion requires development of nonequilibrium quantum thermodynamics. I’ll review our attempts in theoretical formulation of optical spectroscopy, non adiabatic molecular dynamics and quantum thermodynamics using nonequilibrium Green’s function techniques.

References
[1] N. Seshadri and M. Galperin, Phys. Rev. B 103, 085415 (2021).
[2] N. Bergmann and M. Galperin, Eur. Phys. J. Spec. Top. 230, 859-866 (2021).
[3] G. Cohen and M. Galperin, J. Chem. Phys. 152, 090901 (2020).
[4] F. Chen, K. Miwa, and M. Galperin, J. Phys. Chem. A 123, 693-701 (2019).
[5] S. Mukamel and M. Galperin, J. Phys. Chem. C 123, 29015-29023 (2019).
[6] F. Chen, M. A. Ochoa, and M. Galperin, J. Chem. Phys. 146, 092301 (2017).
[7] K. Miwa, F. Chen, and M. Galperin, Sci. Rep. 7, 9735 (2017)
[8] M. Galperin, Chem. Soc. Rev. 46, 4000-4019 (2017).
[9] K. Miwa, A. M. Najarian, R. L. McCreery, and M. Galperin, J. Phys. Chem. Lett. 10, 1550-1557 (2019).
[10] K. Miwa, H. Imada, M. Imai-Imada, K. Kimura, M. Galperin, and Y. Kim, Nano Lett. 19, 2803-2811 (2019).

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Workshop / Seminar Thu, 02 Sep 2021 18:15:47 -0400 2021-09-02T16:00:00-04:00 2021-09-02T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
LAGS Seminar | Never a Dull Moment With a Career in Physics (September 3, 2021 12:00pm) https://events.umich.edu/event/85949 85949-21630599@events.umich.edu Event Begins: Friday, September 3, 2021 12:00pm
Location: West Hall
Organized By: Department of Physics

When I graduated in 1988 from the University of Michigan with a bachelor in physics, I would never have imagined where this degree would take me. I went to Harvard for a PhD in physics and then moved to Europe. I lived in both Austria and Germany, learned German, and did basic research at two universities up to the assistant professor level. Then I transitioned to industry where I gained extensive experience in technical product development, in management as the Managing Director (Geschäftsführerin) of two high tech companies as well as in sales as a Key Account Manager. Today, I design surgical microscopes for ophthalmology. My career is also strongly influenced by the work I do as the president of a non-profit association dedicated to founding an Albert Einstein museum in Ulm, Germany – his birthplace (see https://einstein.center).

Throughout my career, my motto has been: LEARNING BY DOING and it has served me well since I left Ann Arbor. In this seminar, I will share some insights for transitioning from academia to industry and why I found a career in industry and in a non-profit so multifaceted. I will also share my passion for the Einstein museum with anyone attending the seminar.

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Workshop / Seminar Fri, 03 Sep 2021 18:16:03 -0400 2021-09-03T12:00:00-04:00 2021-09-03T13:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
CM-AMO Seminar | A Series of Three Lectures on: Floquet states, Rabi oscillations, Fermi's golden rule and all that (Lecture 2 of 3) (September 7, 2021 4:00pm) https://events.umich.edu/event/85768 85768-21628809@events.umich.edu Event Begins: Tuesday, September 7, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Rabi oscillations arise when a few-level quantum system is subjected to a periodically time-varying field while Floquet states are stationary solutions of a quantum system in the presence of a periodic time-dependent perturbation. Past the simplest derivations, students interested in these topics may miss to grasp the connection between Rabi oscillations and Floquet states beyond the obvious fact that they both involve a time-varying field. Equally important, they may struggle to find pedagogical accounts in the literature discussing the effect of dissipation, which is central to the interpretation of many physical phenomena. They may also ponder about the question as to how Rabi oscillations and Floquet states relate to results of time-dependent perturbation theory, particularly concerning Fermi golden rule and linear response theory. In these series of lectures, aimed at students, we introduce an exactly solvable model of a two-level system coupled to a continuum, which interacts with a sinusoidally time-varying classical field. Results show that the behavior of the two-level system can be mapped onto the problem of a static field, if one shifts the energy separation between the two levels by an amount equal to the frequency of the field. This correspondence allows one to view Rabi oscillations and Floquet states from the different perspective of their time-independent-problem equivalents. The comparison between the rigorous results and those from perturbation theory helps clarify some of the difficulties underlying textbook proofs of Fermi golden rule, and the discussions on quantum decay and linear response theory.

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Workshop / Seminar Tue, 07 Sep 2021 18:15:53 -0400 2021-09-07T16:00:00-04:00 2021-09-07T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department Colloquium | Megaconstellations of Satellites Are About to Ruin the Night Sky for Everyone (September 8, 2021 4:00pm) https://events.umich.edu/event/85798 85798-21629093@events.umich.edu Event Begins: Wednesday, September 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Department Colloquium Zoom link: https://umich.zoom.us/j/94692610056

Several companies are planning to launch megaconstellations of thousands of communication satellites (satcons), which would increase the number of active satellites in Low Earth Orbit at least twenty-fold in the next few years. SpaceX's Starlink satcon is currently largest (almost 2,000 satellites) and is adding 60 new satellites every couple of weeks. While these satcons do allow internet access in many underserved rural and remote locations, the costs are prohibitively high for all but the most well-off customers. These thousands of satellites each reflect sunlight, causing serious problems for research astronomy, and making anthropogenic light pollution a fully global phenomenon that cannot be escaped anywhere on Earth. Because of geometry and the chosen satellite orbits, latitudes near 50 degrees N and S will see the worst light pollution from these satcons. These satellites also contribute to atmospheric pollution, both on launch and re-entry, contribute to diffuse sky emission, and drastically increase the very real threat of Kessler Syndrome. I will talk about how these satellites will affect stargazers and astronomers worldwide, and what you can do to help mitigation efforts.

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Workshop / Seminar Wed, 08 Sep 2021 18:15:50 -0400 2021-09-08T16:00:00-04:00 2021-09-08T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Department of Computational Medicine & Bioinformatics || Weekly Seminar Series (September 8, 2021 4:00pm) https://events.umich.edu/event/86237 86237-21632210@events.umich.edu Event Begins: Wednesday, September 8, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Structural variants (SVs) are a source of pathogenic variants in a clinical referral population, however, they are often under-reported due to technical limitations of detection and difficulty with clinical interpretation. For example, mobile element insertions (MEIs) are estimated to lead to a positive finding in 1 out of 1000 rare genetic disease cases, yet the numbers are far lower in clinical diagnostic laboratories. Targeted NGS with short insert size libraries, unlike genome sequencing, will have very few discordant read pairs to indicate the presence of an SV. We, therefore, developed an SV detection tool called SCRAMble (Soft Clipped Read Alignment Mapper) to identify SV breakpoints in targeted NGS.

We applied SCRAMble to a prospective clinical referral cohort for exome sequencing to identify deletions and MEIs. We also applied SCRAMble to a hereditary cancer panel assay for the identification of a large inversion involving the MSH2 gene that causes Lynch syndrome. Adding breakpoint detection to clinical targeted sequencing identifies positive findings which were missed by prior testing and by other variant callers. Detecting breakpoints allows for more precise interpretation and for more targeted confirmation assays. By applying SV breakpoint detection, we are able to diagnose ~0.3% more cases. While this is a modest gain in diagnostic yield, for the patients and families involved, a positive diagnosis, even after prior testing, can have a meaningful impact on their lives.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 02 Sep 2021 14:28:18 -0400 2021-09-08T16:00:00-04:00 2021-09-08T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Rebecca Torene, Associate Director of Genomics Research | Data Science at GeneDx
Interdisciplinary QC/CM Seminar | Incipient Intertwined Order in the Hubbard Model (September 9, 2021 4:00pm) https://events.umich.edu/event/84819 84819-21625069@events.umich.edu Event Begins: Thursday, September 9, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

The Hubbard model is the paradigmatic model of strongly correlated electron systems. Over the past several years, advanced numerical techniques have led to considerable progress in determining the ground state phases of the model, revealing spin stripe order, charge stripe order, and d-wave superconductivity as the dominant players at low energies. In this talk, I will discuss numerically exact determinantal quantum Monte Carlo calculations demonstrating how the interplay of these orders persists well above the onset of the pseudogap [1]. In particular, I will focus on the nature of fluctuating spin [2,3] and charge [4,5] stripes in the model, and show that they remain mutually commensurate at temperatures where the model exhibits bad metallic transport [6]. I will also discuss connections between these results to recent X-ray scattering experiments on cuprates [7] and possible avenues to explore intertwined orders in cold atom simulations of the Hubbard model.

References:
[1] EWH et al, arXiv:2106.09704.
[2] EWH et al, Science 358, 1161 (2017).
[3] EWH et al, npj Quantum Materials 3, 22 (2018).
[4] P. Mai, S. Karakuzu, G. Balduzzi, S. Johnston, T. A. Maier, arXiv:2106.01944.
[5] EWH, in preparation.
[6] EWH et al, Science 366, 987 (2019).
[7] S. Lee, EWH et al, in preparation.

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Workshop / Seminar Thu, 09 Sep 2021 18:15:49 -0400 2021-09-09T16:00:00-04:00 2021-09-09T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
HET Seminar | A paradigm for open quantum systems with memory from holography (September 10, 2021 3:00pm) https://events.umich.edu/event/86338 86338-21632749@events.umich.edu Event Begins: Friday, September 10, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The late-time, long-distance behaviour of gravitational perturbations of planar AdS black holes is controlled by hydrodynamic quasinormal modes. In the dual CFT these are modes of the conserved currents which control the infra-red dynamics. While the on-shell structure of these modes has been understood for a long-time, we have recently begun to understand how to construct an off-shell low energy effective action, an effective hydrodynamic field theory, from holography. I will describe the general lessons learnt from the gravitational analysis, sketching out a paradigm that provides a template for the analysis of general quantum systems with dissipation and long-time memory.

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Lecture / Discussion Fri, 03 Sep 2021 16:25:22 -0400 2021-09-10T15:00:00-04:00 2021-09-10T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
RNA Innovation Seminar (September 13, 2021 4:00pm) https://events.umich.edu/event/86155 86155-21631746@events.umich.edu Event Begins: Monday, September 13, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

"Recent improvements in modeling and design of RNA-only structures"

ABSTRACT: The discovery and design of biologically important RNA molecules is outpacing three-structural characterization. I'll describe results from my and Wah Chiu's groups that demonstrate that cryo-electron microscopy can resolve maps of several kinds of RNA-only systems. These maps enable subnanometer-resolution 3D coordinate estimation when complemented with multidimensional chemical mapping and Rosetta DRRAFTER computational modeling. If time allows, I'll describe work from the Eterna project to stabilize mRNA molecules to help accelerate worldwide COVID immunization.

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Lecture / Discussion Thu, 02 Sep 2021 12:54:16 -0400 2021-09-13T16:00:00-04:00 2021-09-13T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Rhiju Das, Stanford University
CM-AMO Seminar | A Series of Three Lectures on: Floquet states, Rabi oscillations, Fermi's golden rule and all that (Lecture 3 of 3) (September 14, 2021 4:00pm) https://events.umich.edu/event/85769 85769-21628810@events.umich.edu Event Begins: Tuesday, September 14, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Rabi oscillations arise when a few-level quantum system is subjected to a periodically time-varying field while Floquet states are stationary solutions of a quantum system in the presence of a periodic time-dependent perturbation. Past the simplest derivations, students interested in these topics may miss to grasp the connection between Rabi oscillations and Floquet states beyond the obvious fact that they both involve a time-varying field. Equally important, they may struggle to find pedagogical accounts in the literature discussing the effect of dissipation, which is central to the interpretation of many physical phenomena. They may also ponder about the question as to how Rabi oscillations and Floquet states relate to results of time-dependent perturbation theory, particularly concerning Fermi golden rule and linear response theory. In these series of lectures, aimed at students, we introduce an exactly solvable model of a two-level system coupled to a continuum, which interacts with a sinusoidally time-varying classical field. Results show that the behavior of the two-level system can be mapped onto the problem of a static field, if one shifts the energy separation between the two levels by an amount equal to the frequency of the field. This correspondence allows one to view Rabi oscillations and Floquet states from the different perspective of their time-independent-problem equivalents. The comparison between the rigorous results and those from perturbation theory helps clarify some of the difficulties underlying textbook proofs of Fermi golden rule, and the discussions on quantum decay and linear response theory.

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Workshop / Seminar Tue, 14 Sep 2021 18:16:04 -0400 2021-09-14T16:00:00-04:00 2021-09-14T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department Colloquium | Understanding Human Development Using Pluripotent Stem Cells (September 15, 2021 4:00pm) https://events.umich.edu/event/85799 85799-21629094@events.umich.edu Event Begins: Wednesday, September 15, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

How a complete human body develops from a single fertilized egg cell is among the deepest scientific questions. A crucial stage in this process is called gastrulation, during which the basic body plan is laid out and cells differentiate to the main lineages that will form the different organs. This stage cannot be ethically studied in human embryos and is also difficult to study in other mammals. However, it can be experimentally mimicked in a dish by confining human stem cells into disc shaped colonies. These will then undergo self-organized embryo-like pattern formation while allowing systematic quantitative study. This approach has been used by a small community of mostly physicists-turned-biologists to discover new principles of human development that challenge the existing theories of pattern formation. In my talk I will give an overview of this field, discuss how I ended up there after my PhD in theoretical high energy physics, and show some recent results from my group.

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Workshop / Seminar Wed, 15 Sep 2021 18:16:03 -0400 2021-09-15T16:00:00-04:00 2021-09-15T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar Series (September 15, 2021 4:00pm) https://events.umich.edu/event/86598 86598-21635116@events.umich.edu Event Begins: Wednesday, September 15, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Chromosomal instability (CIN) results in the accumulation of large-scale losses, gains, and rearrangements of DNA. The broad genomic complexity caused by CIN is a hallmark of cancer, however, there is no systematic framework to measure different types of CIN and their impact on clinical phenotypes. Here, we evaluate the extent, diversity and origin of chromosomal instability across 7,880 tumors representing 33 cancer types from the TCGA collection. We present a compendium of 17 copy number signatures characterizing specific types of CIN, with putative aetiologies supported by multiple independent data sources. The signatures predict drug response and identify new drug targets. Our framework refines the understanding of impaired homologous recombination, one of the most therapeutically targetable types of CIN. Our results illuminate a fundamental structure underlying genomic complexity and provide a resource to guide future CIN
research in human cancers.

Bio:

Florian Markowetz is a Senior Group Leader at the Cancer Research UK Cambridge Institute. He is a Royal Society Wolfson Research Merit Award holder and received a CRUK Future Leader in Cancer Research prize. He holds degrees in Mathematics (Dipl. math.) and Philosophy (M.A.) from the University of Heidelberg and a Dr. rer. nat. (PhD equivalent) in Computational Biology from Free University Berlin, for which he was awarded an Otto-Hahn Medal by the Max Planck Society. His group at the CRUK Cambridge Institute combines computational work on cancer evolution and image analysis of the tumor tissue with experimental work on understanding key cancer mechanisms like the estrogen receptor.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 09 Sep 2021 11:24:05 -0400 2021-09-15T16:00:00-04:00 2021-09-15T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Florian Markowetz (Senior Group Leader at the Cancer Research UK Cambridge Institute)
MCAIM Colloquium - Topological Complexity and Optimization of High Dimensional Random Functions (September 15, 2021 4:00pm) https://events.umich.edu/event/86534 86534-21634773@events.umich.edu Event Begins: Wednesday, September 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

Smooth random functions of very many variables can be topologically very complex, and thus it can be terribly hard to find their minimum.One does not need to look very far for such an example: pick at random a homogeneous polynomial of degree p (with p larger than 3) of a large number of variables and restrict it to the (high-dimensional) unit sphere. Important examples of such functions include many Hamiltonians of statistical mechanics in disordered media (as Spin Glasses or Random Interfaces in high disorder). They can also include the loss functions of high dimensional inference problems, and naturally the landscapes defined by Machine Learning.

We will cover some of the recent progress in our understanding of both questions: the statics or geometric question about the topological complexity and the transition to simple landscapes (the so-called topological trivialization), as well as the dynamics and optimization questions.

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Workshop / Seminar Wed, 08 Sep 2021 13:29:44 -0400 2021-09-15T16:00:00-04:00 2021-09-15T17:00:00-04:00 Off Campus Location Michigan Center for Applied and Interdisciplinary Mathematics Workshop / Seminar Gérard Ben Arous, The Courant Institute
HET Seminar | The Impact of a Midband Gravitational Wave Experiment On Detectability of Cosmological Stochastic Gravitational Wave Backgrounds (September 17, 2021 3:00pm) https://events.umich.edu/event/86118 86118-21632221@events.umich.edu Event Begins: Friday, September 17, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

I will discuss the impact of a future midband gravitational wave experiment on improving detectability of a cosmologically sourced stochastic GW background. Specific proposed midband experiments considered are TianGo, B-DECIGO and AEDGE. We propose a combined power-law integrated sensitivity (CPLS) curve combining GW experiments over different frequency bands, which shows significant improvement in sensitivity to SGWBs with the aid of a midband experiment. We consider GW emission from cosmic strings and phase transitions as benchmark examples of cosmological SGWBs. We explicitly model various astrophysical SGWB sources, most importantly from unresolved black hole mergers. Based on analysis using Markov Chain Monte Carlo, we demonstrated that midband experiments can, when combined with LIGO A+ and LISA, can significantly improve sensitivities to cosmological SGWBs and better separate them from astrophysical SGWBs

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Lecture / Discussion Wed, 01 Sep 2021 11:58:12 -0400 2021-09-17T15:00:00-04:00 2021-09-17T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | Quest for KL —> pi0 nu nu-bar (September 20, 2021 4:00pm) https://events.umich.edu/event/86612 86612-21635219@events.umich.edu Event Begins: Monday, September 20, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

The KL —> pi0 nu nu-bar decay is one of the sensitive probes to search for new physics beyond the Standard Model. Because the branching ratio predicted by the Standard Model (3 x 10^{-11}) and its theoretical uncertainty are small, a small deviation from the prediction would signify an existence of new physics. Although the decay mode is theoretically clean, it is difficult to observe experimentally. Not only because the observable particles are limited to two photons from the pi0, backgrounds should be controlled and understood to the level of O(10^-{11}). In this talk, I will briefly review several experimental ideas in the past, explain how the current J-PARC KOTO experiment started and progressed, and show some future plans.

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Workshop / Seminar Mon, 20 Sep 2021 18:16:13 -0400 2021-09-20T16:00:00-04:00 2021-09-20T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
CM-AMO Seminar | How to Create and Leverage Many-Body Entanglement For Near-Term Quantum Networks and Simulation (September 21, 2021 4:00pm) https://events.umich.edu/event/85875 85875-21629503@events.umich.edu Event Begins: Tuesday, September 21, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Quantum information science and related technologies include quantum computers, which will be able to solve important problems beyond the reach of classical computers, as well as the ‘quantum internet’, an inherently secure network for communication and for accessing remote quantum computers. I will discuss these technologies, focusing on the question of how to enable them by creating and leveraging multipartite entangled states using near-term quantum systems. In the case of quantum networks, I will describe our protocols for the generation of logically encoded photonic graph states from quantum emitters. For quantum simulation, I will present our recent work on efficient variational quantum algorithms.

Bio: Sophia Economou is a Professor of Physics and the Hassinger Senior Fellow of Physics at Virginia Tech. She focuses on theoretical research in quantum information science, including quantum computing with solid-state and photonic qubits, quantum communications, and quantum simulation algorithms.

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Workshop / Seminar Tue, 21 Sep 2021 18:16:14 -0400 2021-09-21T16:00:00-04:00 2021-09-21T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department Colloquium | Light up Quantum Matter (September 22, 2021 4:00pm) https://events.umich.edu/event/86207 86207-21632179@events.umich.edu Event Begins: Wednesday, September 22, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Quantum materials are a broad class of materials where collective behaviors of 1023 electrons emerge upon strong interactions and/or reduced dimensionality. Examples include high-Tc superconductivity from strong electron correlations, topological insulators from strong spin orbit coupling, and massless Dirac fermions in two-dimensional (2D) monolayer graphene. Our group works to develop and utilize laser-based spectroscopy and microscopy techniques to reveal, understand, and control quantum states of matter in 3D and 2D quantum materials. In this talk, I will focus on one specific family of phases of matter, multipolar orders, that are widely present in numerous 3D and 2D quantum materials, but at the same time, are extremely hard to study for their little coupling to our familiar vector fields (e.g., electric and magnetic fields). Using the ferro-rotational order, the lowest rank multipolar order, as an example, I will show that we developed static rotation anisotropy (RA) electric quadrupole (EQ) second harmonic generation (SHG) spectroscopy to measure its symmetry properties, built spatially-resolved RA-EQ-SHG microscopy to map its real-space distribution, and designed and constructed time-resolved RA-EQ SHG spectroscopy to resolve its collective excitations and drive it into a new transient state. Our success in developing and using EQ-SHG to study the ferro-rotational order opens new venues for coupling and manipulating these otherwise inaccessible multipolar orders with nonlinear and ultrafast optics.

References

W. Jin*, E. Drueke*, et al Nature Physics 16, 42 (2020)
X. Luo et al Phys. Rev. Letters in press (2021)
X. Guo*, R. Owen*, et al manuscript in preparation (2021)

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Workshop / Seminar Wed, 22 Sep 2021 18:16:19 -0400 2021-09-22T16:00:00-04:00 2021-09-22T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar (September 22, 2021 4:00pm) https://events.umich.edu/event/87282 87282-21640718@events.umich.edu Event Begins: Wednesday, September 22, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Histones are small proteins that package DNA into chromosomes, and a large number of studies have showed that several post-translational modification (PTM) sites on the histones are associated with both gene activation and silencing. Along with DNA and small non-coding RNA, histone PTMs make up epigenetic mechanisms that control gene expression patterns outside of DNA sequence mutations. Dysregulation of these chromatin networks underlie several human diseases such as cancer. Here I will give an update on technology advancements that have allowed for high-throughput quantitative analyses of histone PTMs and chromatin structure, and how we are applying these methods to understand epigenetic reprogramming found in malignant peripheral nerve sheath tumors (MPNSTs). MPNST is an aggressive sarcoma with recurrent loss of function alterations in polycomb-repressive complex 2 (PRC2), a histone-modifying complex involved in transcriptional silencing.

Zoom Link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 20 Sep 2021 15:27:41 -0400 2021-09-22T16:00:00-04:00 2021-09-22T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Interdisciplinary QC/CM Seminar | Learning Without Neurons (September 23, 2021 4:00pm) https://events.umich.edu/event/86558 86558-21634895@events.umich.edu Event Begins: Thursday, September 23, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Learning is usually associated with neural networks. But non-neural systems can also accumulate incremental changes over time and thus respond better to future environments. We show how seemingly 'dumb' physical systems like DNA crystals and elastic materials can learn to recognize complex patterns in chemical or mechanical stimuli, much like a neural network. We outline the potential and limits of such 'mechanical intelligence' due to physically realizable learning dynamics.

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Workshop / Seminar Thu, 23 Sep 2021 18:16:20 -0400 2021-09-23T16:00:00-04:00 2021-09-23T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
HET Seminar | de Sitter decays to infinity (September 24, 2021 3:00pm) https://events.umich.edu/event/87074 87074-21638691@events.umich.edu Event Begins: Friday, September 24, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The bubble of nothing is a gravitational instanton that can be thought of as describing tunneling through a vanishing scalar potential barrier to a vacuum at infinity. I will discuss generalizations of this process to nonzero scalar potentials with metastable de Sitter vacua. In simple cases, approximate bubble-of-nothing solutions can be constructed analytically. More generally, the problem can be formulated as a set of CdL equations with singular boundary conditions and solved numerically.

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Lecture / Discussion Thu, 16 Sep 2021 12:33:58 -0400 2021-09-24T15:00:00-04:00 2021-09-24T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | Galaxy-Galaxy Lensing and Lensing Ratios for Cosmological Analyses in the Dark Energy Survey (September 27, 2021 4:00pm) https://events.umich.edu/event/86495 86495-21634734@events.umich.edu Event Begins: Monday, September 27, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Galaxy cosmic surveys such as the Dark Energy Survey are a powerful tool to extract cosmological information. In particular, the combination of weak lensing and galaxy clustering measurements, usually known as 3x2pt, provides a potent and robust way to constrain the parameters controlling the structure formation in the late Universe. In this talk I will give an overview of the results and methods of Dark Energy Survey Y3 3x2pt cosmological analysis, focusing specially on the galaxy-galaxy lensing probe, which is the cross-correlation of the shapes of source background galaxies with lens foreground galaxy positions. I will also describe how we can construct suitable ratios of these galaxy-galaxy lensing measurements to exploit the otherwise usually disregarded small-scale information and naturally integrate it as part of the 3x2pt analysis. Finally, I will highlight some other galaxy-galaxy lensing applications, including learning about the galaxy-halo connection and low-surface brightness galaxies.

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Workshop / Seminar Mon, 27 Sep 2021 18:16:45 -0400 2021-09-27T16:00:00-04:00 2021-09-27T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department Colloquium | Flat Bands, Topology, and Fractionalization - A New Pathway Towards Fractional Topological States (September 29, 2021 4:00pm) https://events.umich.edu/event/86208 86208-21632180@events.umich.edu Event Begins: Wednesday, September 29, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

In this talk, I will first provide a review about various flat band systems and the nontrivial physics that emerges from these flat bands and heavy electrons, with main focus on fractional topological states and fractional excitations. In contrast to the conventional approach, such as the fractional quantum Hall effect, which requires a strong external magnetic field, here we explore a new pathway towards the same type of exotic fractional particles through spontaneous symmetry breaking with zero external magnetic fields. We show that utilizing realistic material parameters and the method of exact diagonalization, these fractional states can be stabilized in Moiré superlattices of transition metal dichalcogenides (TMD).

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Workshop / Seminar Wed, 29 Sep 2021 18:16:37 -0400 2021-09-29T16:00:00-04:00 2021-09-29T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar (September 29, 2021 4:00pm) https://events.umich.edu/event/87515 87515-21642906@events.umich.edu Event Begins: Wednesday, September 29, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Human complex traits result from genetic and environmental factors, and from their interactions. Many of these effects are mediated by changes in gene regulation. Indeed, most genetic variants associated with complex trait variation in humans are in regulatory regions. I will present some of our recent studies on gene-environment interactions in gene regulation, with a specific focus on cardiovascular health. I will present evidence that gene-environment interactions in molecular phenotypes are frequent, account for a substantial portion of complex trait variation and modify genetic risk for disease.

Research Focus:

My lab is interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes. We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, protein secretion, etc.) and how they are affected by gene-environment interactions. Our research is funded by the NIH.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 24 Sep 2021 14:01:53 -0400 2021-09-29T16:00:00-04:00 2021-09-29T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Francesca Luca, PhD (Wayne State University)
Interdisciplinary QC/CM Seminar | Perfect Andreev Reflection Due to the Klein Paradox in a Topological Superconducting State (September 30, 2021 4:00pm) https://events.umich.edu/event/86559 86559-21634896@events.umich.edu Event Begins: Thursday, September 30, 2021 4:00pm
Location: Mason Hall
Organized By: Department of Physics

One focus of our research is exploration of new quantum materials and their device applications. In this talk, I will describe our observation of perfect Andreev reflection in point contact spectroscopy – a signature of the Klein paradox in a topological superconducting state [1]. Klein tunneling is a manifestation of relativistic physics: shortly after Dirac proposed a new wave equation to describe relativistic electrons in 1928, Klein solved a simple potential step problem for the Dirac equation and stumbled upon an apparent paradox, where the potential becomes transparent when the height is larger than the electron energy. For massless particles, backscattering is completely forbidden in Klein tunneling, leading to perfect transmission through any potential barrier. Recent advent of condensed matter systems with Dirac-like excitations, such as graphene and topological insulators, has opened the possibility of directly observing the Klein tunneling experimentally. In the surface states of topological insulators, electrons are bound by spin-momentum locking, and are thus immune to backscattering due to time-reversal symmetry. We establish a proximity-induced topological superconducting state using a topological Kondo insulator SmB6 coupled to YB6. Klein tunneling through point contact Andreev reflection results in exact doubling of conductance within the superconducting gap, a very rarely observed phenomenon. I will discuss potential device applications of superconducting Klein tunneling. I will also discuss our methodology for high-throughput exploration of new superconductors. This work is funded by ONR and AFOSR.

[1] Lee et al., Nature 570, 344 (2019).

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Workshop / Seminar Thu, 30 Sep 2021 18:16:19 -0400 2021-09-30T16:00:00-04:00 2021-09-30T17:00:00-04:00 Mason Hall Department of Physics Workshop / Seminar Mason Hall
Super-Chern-Simons spectra from Exceptional Field Theory (October 1, 2021 3:00pm) https://events.umich.edu/event/87333 87333-21641172@events.umich.edu Event Begins: Friday, October 1, 2021 3:00pm
Location: West Hall
Organized By: Leinweber Center for Theoretical Physics

The spectrum of single-trace operators of holographic CFTs at strong
coupling and large N can be mapped to the spectrum of Kaluza-Klein (KK)
excitations over the dual AdS supergravity solutions. Unfortunately,
computing these KK spectra is usually a prohibitively difficult task
even for the simplest AdS solutions. In this talk, I will introduce new
spectral methods based on Exceptional Field Theory that, for certain
AdS/CFT dual pairs, bypass all difficulties and reduce the KK spectral
problem to a simple diagonalisation of suitable mass matrices. I will
illustrate these methods for a class of super-Chern-Simons CFT3s with
AdS4 duals in M-theory and type IIA string theory.

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Lecture / Discussion Wed, 29 Sep 2021 14:45:46 -0400 2021-10-01T15:00:00-04:00 2021-10-01T16:00:00-04:00 West Hall Leinweber Center for Theoretical Physics Lecture / Discussion West Hall
HEP-Astro Seminar | Mu2e: The Muon-to-Electron Conversion Experiment at Fermilab (October 4, 2021 4:00pm) https://events.umich.edu/event/86656 86656-21635380@events.umich.edu Event Begins: Monday, October 4, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

The Mu2e Experiment, based at Fermilab, will search for the coherent, neutrino-less conversion of a negative muon into an electron in the field of an aluminum nucleus. Such a process would exhibit Charged Lepton Flavor Violation (CLFV). Observation of CLFV would be an unambiguous signal of physics beyond the Standard Model (BSM). Mu2e aims to improve the previous upper limit by four orders of magnitude, and reach an unprecedented single-event-sensitivity of 3 × 10^{−17} on the conversion rate, a 90% CL of 8 ×10^{−17}, and a 5σ discovery reach at 2 ×10^{−16}. Mu2e is sensitive to a wide range of BSM models and will indirectly probe mass scales up to 10^4 TeV/c^2. To achieve its design goal, Mu2e will utilize an integrated system of solenoids to create the most intense muon beam in the world. The background will be well-understood and kept at a sub-event level. Mu2e will be an indispensable piece of the global search for BSM over the next decade. The experiment is approaching a very important and exciting stage in its life-cycle. Construction is well underway. Many components have already been procured, delivered and fully tested. Operations are scheduled to begin in the upcoming years. This talk will explore the physics motivations, design, and current status of the Mu2e Experiment.

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Workshop / Seminar Mon, 04 Oct 2021 18:16:20 -0400 2021-10-04T16:00:00-04:00 2021-10-04T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
RNA Innovation Seminar (October 4, 2021 4:00pm) https://events.umich.edu/event/86162 86162-21631753@events.umich.edu Event Begins: Monday, October 4, 2021 4:00pm
Location: 1027 E. Huron Building
Organized By: Center for RNA Biomedicine

"Fluorescent nucleoside analogues with new properties"

HYBRID EVENT
in-person: Forum Hall, Palmer Commons
Zoom: https://umich.zoom.us/webinar/register/WN__vvE2dtHQi-R3h05JUHBzQ

ABSTRACT
Fluorescent nucleoside analogues (FNAs) are powerful probes for studying the structure and dynamics of nucleic acids, which are vital to understanding RNA function, DNA damage repair, nucleic acid–protein interactions, regulatory mechanisms for gene expression, and other aspects of nucleic acid function. Existing FNAs are prone to quenching by base pairing and stacking, are clustered at the blue–green end of the visible spectrum, and have limited brightness as compared with conventional fluorophores. Studies of nucleic acid function would benefit greatly from overcoming these limitations. We have designed, synthesized, and studied a series of fluorescent pyrimidine analogues, aiming to address these limitations and develop a detailed understanding of the relationships between chemical structure and fluorescent responses to local environment in nucleic acids. Included in this series is a tricyclic cytidine analogue DEAtC that is nearly non-fluorescent as a nucleoside, but responds to matched base pairing and stacking with a fluorescence turn-on. A chlorinated tricyclic cytidine 8-Cl-tCO reports on local environment by changes in the vibrational fine structure of its emission spectra. To address the problem of limited brightness, we have design and synthesized a new NFA that we call ABN, which has a conjugated push–pull system similar to those found in bright fluorophores such as rhodamines. ABN is the brightest known FNA when present in duplex nucleic acids, and it is readily detected in single-molecule fluorescence measurements using both 1-photon and 2-photon excitation. Collectively, these FNAs offer new capabilities for biophysical studies on nucleic acids. Comparisons of their structure and properties help to reveal mechanisms for fluorescence changes in response to local environment in nucleic acids.

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Lecture / Discussion Fri, 10 Sep 2021 11:29:04 -0400 2021-10-04T16:00:00-04:00 2021-10-04T17:00:00-04:00 1027 E. Huron Building Center for RNA Biomedicine Lecture / Discussion Byron Purse, San Diego State University
CM-AMO Seminar | Sub-kHz Excitation Lasers For Quantum Information Processing With Rydberg Atoms (October 5, 2021 4:00pm) https://events.umich.edu/event/86423 86423-21634282@events.umich.edu Event Begins: Tuesday, October 5, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Georg A Raithel is inviting you to a scheduled Zoom meeting.
Topic: Remy Legaie seminar
Time: Oct 5, 2021 03:45 PM Eastern Time (US and Canada) Join Zoom Meeting
https://umich.zoom.us/j/93856929175 Meeting ID: 938 5692 9175
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Neutral atoms provide an excellent resource for quantum information processing, combining the long atomic coherence times of the hyperfine ground-state with strong dipole-dipole interactions of highly excited Rydberg states for generating deterministic entanglement between qubits separated by < 10 µm [1].

For robust Rydberg excitation of atomic qubits for gate operations, the two-photon excitation must be detuned from the intermediate excited state to avoid losses due to spontaneous emission. High fidelity gates also require narrow linewidth excitation lasers with excellent long term frequency stability. These requirements can be met using lasers stabilized to a high-finesse optical cavity, exploiting techniques developed for lasers on state-of-the-art optical lattice clocks. Recently, details of cavity stabilized lasers systems for Rydberg excitation of K, Rb, and Sr atoms have been presented, achieving typical linewidths around 1-10 kHz.

In this talk, I will present the construction and characterization of three continuous wave (CW) sub-kHz linewidth lasers stabilized simultaneously to an ultra-high finesse Fabry-Perot cavity made of ultra-low expansion (ULE) glass, with tunable offset-lock frequency [2]. Furthermore, high-resolution electromagnetically induced transparency (EIT) spectroscopy of cold Cs Rydberg states is used to calibrate the cavity mode frequencies with respect to Rydberg transitions and determine the cavity long term drift of ∼ 1 Hz/s. These measurement are competitive against doubly-stabilized optical clocks and offer an order of magnitude improvement compared to similar cavity stabilized Rydberg laser systems.

[1] M. Saffman, T. Walker, and K. Mølmer, Rev. Mod. Phys. 82, 2313 (2010).
[2] R. Legaie et al., J. Opt. Soc. Am. B 35, 892 (2018).

Remy Legaie obtained his PhD in Physics from the University of Strathclyde (Glasgow, Scotland) in 2019, focusing on quantum information processing with ultra-cold Rydberg atoms. He then held a first postdoctoral position at CNRS (Marseille, France) in optical frequency metrology using laser cooled trapped ions. At the beginning of 2021, he was recruited at ENS Paris-Saclay (Paris, France) for a second postdoctoral position, in charge of developing a new experiment using Rydberg atoms in vapor cell as radio frequency field sensor.

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Workshop / Seminar Tue, 05 Oct 2021 18:16:12 -0400 2021-10-05T16:00:00-04:00 2021-10-05T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Self-Organised Localisation (October 6, 2021 1:00pm) https://events.umich.edu/event/87669 87669-21644963@events.umich.edu Event Begins: Wednesday, October 6, 2021 1:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

I will describe a new phenomenon in quantum cosmology: self-organised localisation. When the fundamental parameters of a theory are functions of a scalar field subject to large fluctuations during inflation, quantum phase transitions can act as dynamical attractors. As a result, the theory parameters are probabilistically localised around the critical value and the Universe finds itself at the edge of a phase transition. We illustrate how self-organised localisation could account for the observed near-criticality of the Higgs self-coupling, the naturalness of the Higgs mass, or the smallness of the cosmological constant.

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Lecture / Discussion Wed, 29 Sep 2021 09:33:40 -0400 2021-10-06T13:00:00-04:00 2021-10-06T14:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Department Colloquium | Bringing together Quantum Chemistry and Physics with Ultracold Molecules (October 6, 2021 4:00pm) https://events.umich.edu/event/87073 87073-21638673@events.umich.edu Event Begins: Wednesday, October 6, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link: https://umich.zoom.us/j/94692610056

Advances in quantum manipulation of molecules bring unique opportunities, including the use of molecules to search for new physics, harnessing molecular resources for quantum engineering, and exploring chemical reactions in the ultra-low temperature regime. In this talk, I will focus on the latter two topics. First, I will introduce our effort on building single ultracold molecules with full internal and motional state control in optical tweezers for future quantum simulators and computers. This work allows us to go beyond the usual paradigm of chemical reactions that proceed via stochastic encounters between reactants, to a single, controlled reaction of exactly two atoms. Second, I will summarize our work giving a detailed microscopic picture of molecules transforming from one species to another. We develop full quantum state mapping of chemical reaction product-pairs from single events, which we use to precisely benchmark statistical theory.

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Workshop / Seminar Wed, 06 Oct 2021 18:16:31 -0400 2021-10-06T16:00:00-04:00 2021-10-06T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
LAGS Seminar | Finished Graduate School-Now What? (October 8, 2021 12:00pm) https://events.umich.edu/event/87000 87000-21638112@events.umich.edu Event Begins: Friday, October 8, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Physics

Join Zoom Meeting
https://umich.zoom.us/j/96489263490
Meeting ID: 964 8926 3490
Passcode: 313712

Traditionally, doctoral graduates pursue faculty positions. However, with changing times, demographics, and little to no faculty positions readily available, graduates are forced to explore other employment options. This talk will discuss my experiences in academic post-doctoral research, the AAAS government science and technology fellowship and employment in government research and development.

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Workshop / Seminar Fri, 08 Oct 2021 18:16:05 -0400 2021-10-08T12:00:00-04:00 2021-10-08T13:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HEP-Astro Seminar | The DES Year-3 Cosmic Shear Results (October 11, 2021 4:00pm) https://events.umich.edu/event/86496 86496-21634735@events.umich.edu Event Begins: Monday, October 11, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

The Dark Energy Survey (DES) has recently completed the blinded analysis of its first 3 years of data. We have obtained cosmological constraints from a powerful weak lensing data set of more than 100 million galaxies spanning an effective area of over 4000 square degrees. In this talk, I will present the constraints on the lensing amplitude parameter S8 that come from cosmic shear correlations in DES Y3. I will describe what the DES Y3 results add to our understanding of the apparent tension in S8 between low-redshift weak lensing constraints and those inferred via the Cosmic Microwave Background (CMB). I will also describe our approach to mitigating the main modeling/astrophysical systematics of cosmic shear, namely baryons and intrinsic alignments (IA), and what our data says about the IA signal under a Bayesian model selection method. I will finally comment on a novel detection of 3-point shear correlations and what to expect from DES Y6.

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Workshop / Seminar Mon, 11 Oct 2021 18:16:28 -0400 2021-10-11T16:00:00-04:00 2021-10-11T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
CM-AMO Seminar | Searching for New Fundamental Physics with Polyatomic Molecules (October 12, 2021 4:00pm) https://events.umich.edu/event/87372 87372-21641629@events.umich.edu Event Begins: Tuesday, October 12, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Join Zoom Meeting
https://umich.zoom.us/j/99745863111
Meeting ID: 997 4586 3111
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+13462487799,,99745863111# US (Houston)
+16468769923,,99745863111# US (New York)

The fact that the universe is made entirely out of matter, and contains no free anti-matter, has no physical explanation. The unknown process that created matter in the universe must violate a number of fundamental symmetries, including those that forbid the existence of certain electromagnetic moments of fundamental particles whose signatures are amplified by the large internal fields in polar molecules. We discuss spectroscopic and theoretical investigations into polyatomic molecules that uniquely combine multiple desirable features for precision measurement, such as high polarizability through symmetry-lowering mechanical motions, novel electronic and bonding structures, laser cooling, and exotic nuclei.

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Workshop / Seminar Tue, 12 Oct 2021 18:16:02 -0400 2021-10-12T16:00:00-04:00 2021-10-12T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
MIPSE Seminar | Scaling Intense Laser-Atom Interactions from Low to High Frequency (October 13, 2021 3:30pm) https://events.umich.edu/event/86289 86289-21632590@events.umich.edu Event Begins: Wednesday, October 13, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Over the past three decades, the tailoring of a light field for manipulating the dynamics of a system at the quantum level has taken a prevalent role in modern atomic, molecular and optical physics. As first described by L. V. Keldysh, the ionization of an atom by an intense laser field will evolve depending upon the light characteristics and atomic binding energy. Numerous experiments have systematically investigated the dependence of the intensity and pulse duration on the ionization dynamics. However, exploration of the wavelength dependence has been mainly confined to wavelengths near 1 μm, or in the language of Keldysh to the multiphoton or mixed ionization regime. It is technically possible to perform more thorough test the strong-field limit (tunneling), and exploit the scaling laws at wavelengths greater than 1 μm. In addition, the emergence of XFELs has broadened the scope into the x-ray regime. This new perspective on strong-field interactions is driving a renewed interest in the fundamental physics and a renaissance in applications. This talk will examine the implication of the strong-field scaling as it pertains to the production of energetic particles, the generation of attosecond pulses and molecular imaging.

About the Speaker:
Louis F. DiMauro is Professor of Physics and Hagenlocker Chair at the Ohio State University (OSU). He received his BA (1975) from Hunter College, CUNY and his Ph.D. from University of Connecticut in 1980 and was a postdoctoral fellow at SUNY Stony Brook before arriving at AT&T Bell Laboratories in 1981. He joined the staff at Brookhaven National Laboratory in 1988 rising to the rank of senior scientist. In 2004 he joined the faculty at OSU. He was awarded 2004 BNL/BSA Science & Technology Prize, 2012 OSU Distinguish Scholar Award, the 2013 OSA Meggers Prize and the 2017 APS Schawlow Prize in Laser Science. He is a Fellow of the American Physical Society, the Optical Society of American and the American Association for the Advancement of Science. He has served on numerous national and international committees, government panels, as the 2010 APS DAMOP chair, vice-chair of the NAS CAMOS committee and currently serves on the NAS Board of Physics and Astronomy. His research interests are in experimental ultra-fast and strong-field physics. In 1993, he and his collaborators introduced the widely accepted semi-classical model in strong-field physics. His current work is focused on the generation, measurement and application of attosecond x-ray pulses and the study of fundamental scaling of strong field physics.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 10:57:53 -0400 2021-10-13T15:30:00-04:00 2021-10-13T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Louis DiMauro
2021 Ta You Wu Lecture in Physics | A Nocturnal Discovery that Triggered a Revolution in International Metrology (October 13, 2021 4:00pm) https://events.umich.edu/event/84775 84775-21624933@events.umich.edu Event Begins: Wednesday, October 13, 2021 4:00pm
Location: Rackham Graduate School (Horace H.)
Organized By: Department Colloquia

The quantum Hall effect, an unexpected discovery at 2 a.m. on the 5th of February 1980 led to my Nobel Prize in 1985 and to a realization of a resistance standard based on fundamental constants. Since fundamental constants are the most stable quantities in our universe, a new international system of units based on constants of nature was introduced in 2019. The talk presents an overview of the quantum Hall effect and this importance for our new definition of the mass unit kilogram.

Doors to the fourth floor Rackham Amphitheatre will open at 3:00 pm for seating. Please come early! Per University policy, each guest will need to wear a face-covering and respond to the ResponsiBLUE COVID Screening Check via their smartphone: https://responsiblue.umich.edu/sign-in

This will be an in-person event and will also be live-streamed. Livestreamed on YouTube, https://myumi.ch/r8Dlz.

More information on the Ta-You Wu event webpage: https://myumi.ch/xmvm8

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Presentation Wed, 06 Oct 2021 10:31:49 -0400 2021-10-13T16:00:00-04:00 2021-10-13T17:00:00-04:00 Rackham Graduate School (Horace H.) Department Colloquia Presentation Klaus von Klitzing, Nobel Laureate in the cryostat lab
Department of Computational Medicine & Bioinformatics Weekly Seminar (October 13, 2021 4:00pm) https://events.umich.edu/event/86441 86441-21634316@events.umich.edu Event Begins: Wednesday, October 13, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Understanding the genetic and molecular architecture of human disease is accelerated by robust model development and large-scale molecular profiling. I will present two studies leveraging big data analytics or automated machine learning to dissect human disease complexities: 1) Molecular and clinical signatures of SARS-CoV-2 infection in the US marines. This analysis revealed strong antiviral innate immunity set point in females contributing to sex differences in both molecular and clinical response to SARS-CoV-2 infection. A set of accurate biomarkers capable of detecting PCR false negative infections was implemented on small footprint devices. 2) Automated machine learning to interpret the effects of genetic variants. An automated framework, AMBER, was developed for efficiently searching neural network architectures to model genomic sequences. AMBER is useful in various biological applications, including fine mapping variants, partitioning genetic heritability, and in personalized medicine enabled by CRISPR/Cas9 genome editing. Together, these efforts demonstrate quantitative methods coupled with large-scale biomedical data as an effective avenue to decode human regulatory and disease biology.

Short Bio:

Frank Zhang is a Flatiron research fellow with Olga Troyanskaya at the Simons Foundation and Princeton University since 2019. Prior to that, he obtained his PhD at UCLA with Yi Xing. His research focuses on machine learning and statistical method developments for the prediction and interpretation of human molecular and genetic variations using biological big data. Recently, he works on adopting and developing cutting-edge neural architecture search methods to automate the design of deep neural networks in genomics. He is also interested in making deep learning in biomedicine more interpretable and equitable.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 07 Sep 2021 14:45:38 -0400 2021-10-13T16:00:00-04:00 2021-10-13T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
RNA Innovation Seminar: Tim Stasevich, Ph.D., Colorado State University (October 18, 2021 4:00pm) https://events.umich.edu/event/86166 86166-21631758@events.umich.edu Event Begins: Monday, October 18, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

KEYWORDS: translational regulation, gene expression, fluorescence microscopy, intrabodies, single-molecule imaging

ABSTRACT: My lab is creating technology to image mRNA translation in real time and with single-molecule precision in living cells. In this talk, I will introduce our technology and describe how it can be used to amplify fluorescence from newly synthesized proteins as they are being translated from single mRNAs. I will show how we quantify these signals to determine the size, shape, subcellular localization, and mobilities of mRNA translation sites, as well as their protein synthesis dynamics. I will then highlight a few recent applications of our technology, focusing mainly on a new biosensor we have developed to quantify how individual regulatory factors impact single mRNA translation dynamics. Using this biosensor, we provide evidence that human Argonaute2 (Ago2) shuts down translation by down regulating translation initiation on the minutes timescale and helping usher translationally silent mRNAs into P-bodies on the hours timescale. I will conclude by discussing new fluorescent intrabodies my lab is engineering to light up nascent and mature proteins in multiple colors. As these intrabodies can be encoded on plasmids, they can easily be adapted by other labs to image gene activity in diverse living systems.
Timothy J. Stasevich is an Associate Professor in the Department of Biochemistry and Molecular Biology at Colorado State University (CSU). His lab uses a combination of advanced fluorescence microscopy, genetic engineering, and computational modeling to study the dynamics of gene regulation in living mammalian cells. His lab helped pioneer the imaging of real-time single-mRNA translation dynamics in living cells1. Dr. Stasevich received his B.S. in Physics and Mathematics from the University of Michigan, Dearborn, and his Ph. D. in Physics from the University of Maryland, College Park. He transitioned into experimental biophysics as a post-doctoral research fellow in the laboratory of Dr. James G. McNally at the National Cancer Institute. During this time, he developed technology based on fluorescence microscopy to help establish gold-standard measurements of live-cell protein dynamics. Dr. Stasevich next moved to Osaka University, where he worked with Dr. Hiroshi Kimura as a Japan Society for the Promotion of Science Foreign Postdoctoral Research Fellow. While there, he helped create technology to image endogenous proteins and their post-translation modifications in vivo. This allowed him to image the live-cell dynamics of epigenetic histone modifications during gene activation for the first time2. Before joining the faculty at CSU, Dr. Stasevich spent a year as a Visiting Fellow at the HHMI Janelia Research Campus, where he applied superresolution fluorescence microscopy to improve the spatiotemporal resolution of endogenous protein imaging in live cells.
1. Morisaki, T. et al. Real-time quantification of single RNA translation dynamics in living cells. Science 352, 1425–1429 (2016).
2. Stasevich, T. J. et al. Regulation of RNA polymerase II activation by histone acetylation in single living cells. Nature 516, 272–275 (2014).

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Lecture / Discussion Thu, 30 Sep 2021 10:17:54 -0400 2021-10-18T16:00:00-04:00 2021-10-18T17:00:00-04:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Tim Stasevich, Colorado State University
MIPSE Seminar | A New Regime of HED Physics: Coupling High-Rep-Rate Lasers with Cognitive Simulation (October 20, 2021 3:30pm) https://events.umich.edu/event/86293 86293-21632602@events.umich.edu Event Begins: Wednesday, October 20, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
As high-intensity short-pulse lasers that can operate at high-repetition-rate (HRR) (>10 Hz) come online around the world, the high-energy-density (HED) science they enable will experience a radical paradigm shift. The >103 increase in shot rate over today’s shot-per-hour drivers translates into dramatically faster data acquisition and more experiments, and thus the potential to significantly accelerate the advancement of HED science. However, to fully realize the potential benefits of HRR facilities requires a fundamental shift in how they are operated, and in fact, how the experiments performed on them are designed and executed. Current energetic driver facilities depend on the ability to manually tune the lasers, the targets, the diagnostics settings, and more, between single shots or sets of shots through a manual feedback loop of data collection, data analysis, and optimization largely driven by experience and intuition. At 10 Hz, this paradigm is no longer sustainable as more complex data is collected more quickly than is possible to analyze manually. Simultaneously, on-the-fly optimization of experiments will become ever more crucial as higher repetition rates will lead to more deliberate inter-shot variations and the improved operational range to allow exploration over larger regions of phase space. Consequently, it is likely that the next generation of laser facilities will be limited not by their hardware but by our ability to use that hardware effectively. We will present the vision and ongoing work to realize a HRR framework for rapidly delivered optimal experiments coupled to cognitive simulation to provide new insights in HED science.

About the Speaker: Dr. Tammy Ma is the Advanced Photon Technologies Program Element Leader for High-Intensity Laser High Energy Density (HED) Science within NIF & Photon Sciences at the Lawrence Livermore National Lab. Her group pioneers use of the highest intensity lasers in the world to investigate novel high energy density states of matter, generate energetic beams of particles, study laboratory astrophysics, and explore fusion physics. Dr. Ma graduated with a B.S. from the California Institute of Technology, and received her M.S. and Ph.D. from the U of California at San Diego. She has authored or co-authored over 185 refereed journal publications, and currently sits on the Fusion Energy Sciences Advisory Committee (FESAC), providing advice to the U.S. DOE’s Office of Science on issues related to fusion energy and plasma research. She is the recipient of the Presidential Early Career Award for Science and Engineering (PECASE), the APS Thomas H. Stix Award for her work in quantifying hydrodynamic in-stability mix in ICF implosions, and the DOE Early Career Research Award. She currently also serves as LLNL’s Deputy Director for Laboratory Directed Research & Development (LDRD) Program.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:30:42 -0400 2021-10-20T15:30:00-04:00 2021-10-20T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Dr. Tammy Ma
Department Colloquium | The Quark Gluon Plasma: A Look Inside the Hottest Matter in the Universe (October 20, 2021 4:00pm) https://events.umich.edu/event/87158 87158-21639218@events.umich.edu Event Begins: Wednesday, October 20, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Under normal conditions quarks and gluons are confined within protons and neutrons, which in turn are confined to the atomic nucleus. However, in the early universe, about a millionth of a second after the Big Bang,the temperature was hot enough that neither nuclei nor protons and neutrons had formed. This matter, consisting of deconfined quarks and gluons is called the Quark Gluon Plasma. This matter can be recreated in laboratory experiments at the Large Hadron Collider (LHC) at CERN and the Relativistic Heavy Ion Collider (RHIC) and Brookhaven National Laboratory by colliding pairs of nuclei at ultrarelativistic energies. Interestingly, a good description of the bulk properties of this matter can be made in terms of nearly ideal hydrodynamics. A major focus of the current effort in this field is to understand how this fluid behavior emerges from the interactions between the quarks and gluons. The main experimental tool in this study is high momentum quarks and gluons, jets, passing through the plasma which act as short length scale probes. Measurements using the first LHC data from collisions between two lead nuclei at top energies have recently become available and I will discuss what we have learned from these measurements as well as how upcoming data from the LHC and RHIC will together constrain the inner workings of the quark gluon plasma.

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Workshop / Seminar Wed, 20 Oct 2021 18:15:57 -0400 2021-10-20T16:00:00-04:00 2021-10-20T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar (October 20, 2021 4:00pm) https://events.umich.edu/event/88315 88315-21652404@events.umich.edu Event Begins: Wednesday, October 20, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

The Ye lab is focused on harnessing the power of single cell and computational genomics to understand how immune cells sense and respond to their environment. Utilizing new experimental methods we have developed to enable multiplexed single-cell sequencing, I will describe results from sequencing 1.2M cells from ~250 samples to understand the cellular and molecular bases of systemic lupus erythmatosus and COVID-19. I will also describe how population scale single cell sequencing can enable dissection of the genetic architecture of gene expression and annotation of disease associated variants. Finally, I’ll touch on novel experimental workflows to further increase the throughput of single-cell genomics and for encoding orthogonal information into single-cell sequencing assays.

Research Overview:

The Ye lab is interested in how the interaction between genetics and environment affect human variation at the level of molecular phenotypes. To study these interactions, the lab couples high-throughput sequencing approaches that measure cellular response under environmental challenges with population genetics where such measurements are collected and analyzed across large patient cohorts. The lab develops novel experimental approaches that enable the large-scale collection of functional genomic data *en masse* and computational approaches that translate the data into novel biological insights. This approach is used to initially study primary human immune cells in both healthy and diseased patients to understand host pathogen interactions and its role in autoimmunity.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 15 Oct 2021 14:50:45 -0400 2021-10-20T16:00:00-04:00 2021-10-20T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Interdisciplinary QC/CM Seminar | Can We Simulate the Quantum Dynamics of Many Electrons Both, Accurately and Fast? (October 21, 2021 2:00pm) https://events.umich.edu/event/86560 86560-21634897@events.umich.edu Event Begins: Thursday, October 21, 2021 2:00pm
Location: Off Campus Location
Organized By: Department of Physics

Join Zoom Meeting
https://umich.zoom.us/j/94099710193
Meeting ID: 940 9971 0193
Passcode: 761515

The accurate description of the ultrafast quantum dynamics of mutually interacting particles is of high interest in many areas of physics and chemistry. This includes the response of electrons in atoms, molecules, solids, and plasmas to short laser pulses. Similar phenomena occur in optical lattices where cold atoms are driven out of equilibium by ultrafast changes of the lattice parameters (quenches) [1]. A third example is the collective response of electrons in correlated 2D materials to the impact of charged particles [2]. Common to all these systems is that the interaction between the particles (i.e. correlations) significantly affects the time evolution. Common is also that for these systems a solution of the Schrödinger equation is impossible.

I will report how we approach the quantum dynamics of interacting particles. We apply the method of nonequilibrium Green functions (NEGF) which has proven to be a powerful tool to capture electron-electron correlations [3]. However, NEGF simulations are computationally expensive due to their cubic scaling with the simulation duration T. With the introduction of the generalized Kadanoff-Baym ansatz [4], quadratic scaling could be achieved for second order Born (SOA) selfenergies [5], which has substantially extended the scope of NEGF simulations. Recently [6], we could achieve linear scaling within SOA and even the GW and dynamically screened ladder approximations which is a break through for simulating the correlated electron dynamics.

[1] N. Schlünzen et al., Phys. Rev. B 93, 035107 (2016)
[2] K. Balzer et al., Phys. Rev. Lett. (2018)
[3] K. Balzer and M. Bonitz, Lect. Notes Phys. 867 (2013)
[4] P. Lipavský et al., Phys. Rev. B 34, 6933 (1986)
[5] S. Hermanns et al., Phys. Scripta T151, 014036 (2012)
[6] N. Schlünzen et al., Phys. Rev. Lett. 124, 076601 (2020); Joost
et al., Phys. Rev. B 101, 245101 (2020)

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Workshop / Seminar Thu, 21 Oct 2021 18:16:00 -0400 2021-10-21T14:00:00-04:00 2021-10-21T15:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Quantum effects, neutrino masses and new oscillation phenomena (October 22, 2021 3:00pm) https://events.umich.edu/event/87771 87771-21645838@events.umich.edu Event Begins: Friday, October 22, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

In this seminar I will discuss how quantum effects sourced by the neutrino mass mechanism can leave imprints on neutrino oscillations. More precisely, in the presence of relatively light new physics, the scale dependence of the mixing parameters can lead to observable effects in neutrino experiments. We discuss some of the experimental signatures of this scenario and present simple, UV complete models of neutrino masses which lead to observable running of the neutrino mixing matrix below the weak scale.

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Lecture / Discussion Fri, 01 Oct 2021 10:45:39 -0400 2021-10-22T15:00:00-04:00 2021-10-22T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | The Search for New Physics With Rare Kaon Decays at the CERN SPS (October 25, 2021 4:00pm) https://events.umich.edu/event/86657 86657-21635381@events.umich.edu Event Begins: Monday, October 25, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link:
https://umich.zoom.us/j/91409362110?pwd=UDlja2FuYlZWVFNEMWFrOTlkWFNEZz09

Precise measurements of the branching ratios (BRs) for the flavor-changing neutral current decays K → πνν ̄ can provide unique constraints on CKM unitarity and, potentially, evidence for the existence of new physics. The NA62 experiment at the CERN SPS was designed to measure BR(K + → π +νν) with a precision of about 10%. The key features of the experiment include ultrafast tracking for both beam and secondary particles, redundant particle identification, hermetic photon vetoes, and high-performance electromagnetic calorimetry. The experiment took data from 2016–2018 before LHC Long Shutdown 2, obtaining a measurement of BR(K + → π + νν) in agreement with the Standard Model prediction, establishing the existence of the decay at the 3.4σ level and providing new constraints on models for physics beyond the Standard Model. The data collected in 2016–2018 correspond to 20% of the expected total; the experiment restarted data taking in July 2021 and will be completed in 2024. Over the longer term, the continued availability of the primary proton beam from the CERN SPS through at least 2036 provides an opportunity for an integrated program for precise measurements of rare kaon decays, both charged and neutral, to give clear insight into the flavor structure of new physics. This program will make use of a significantly upgraded NA62-like setup with detectors that can be reconfigured and reused in various experimental stages, including a measurement of BR(K + → π + νν) to ∼5%, a measurement of BR(KL → π 0 νν) to ∼20% (KLEVER), and a program with a neutral beam and downstream detectors for tracking and particle identification to allow the study of decays such as KL → π^0 \ell^+ \ell^−. In this seminar, the recent results from NA62 will be reviewed, and future directions for the kaon program at CERN will be described.

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Workshop / Seminar Mon, 25 Oct 2021 18:15:57 -0400 2021-10-25T16:00:00-04:00 2021-10-25T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
HET Seminar | Perspectives and Questions (October 27, 2021 12:00pm) https://events.umich.edu/event/87768 87768-21645834@events.umich.edu Event Begins: Wednesday, October 27, 2021 12:00pm
Location: West Hall
Organized By: Leinweber Center for Theoretical Physics

Meditations on the future of particle physics.

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Lecture / Discussion Fri, 01 Oct 2021 09:50:51 -0400 2021-10-27T12:00:00-04:00 2021-10-27T13:00:00-04:00 West Hall Leinweber Center for Theoretical Physics Lecture / Discussion West Hall
Department Colloquium | A Century of Noether's Theorem (October 27, 2021 4:00pm) https://events.umich.edu/event/87159 87159-21639219@events.umich.edu Event Begins: Wednesday, October 27, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

In the summer of 1918, Emmy Noether published the theorem that now bears her name, establishing a profound two-way connection between symmetries and conservation laws. The influence of this insight is pervasive in physics; it underlies all of our theories of the fundamental interactions and gives meaning to conservation laws that elevates them beyond useful empirical rules. Noether’s papers, lectures, and personal interactions with students and colleagues drove the development of abstract algebra, establishing her in the pantheon of twentieth-century mathematicians. This essay traces her path from Erlangen through Göttingen to a brief but happy exile at Bryn Mawr College, illustrating the importance of "Noether's Theorem" for the way we think today.

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Workshop / Seminar Wed, 27 Oct 2021 18:15:57 -0400 2021-10-27T16:00:00-04:00 2021-10-27T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar (October 27, 2021 4:00pm) https://events.umich.edu/event/88276 88276-21652019@events.umich.edu Event Begins: Wednesday, October 27, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
Molecular classification has transformed the diagnosis and treatment of diffuse gliomas, creating targets for precision therapies. However, timely and efficient access to molecular diagnostic methods remains difficult, causing a significant barrier to deliver molecularly-targeted therapies. We aim to develop an innovative point-of-care diagnostic screening method that provides rapid and accurate molecular classification of diffuse gliomas through artificial intelligence and optical imaging in order to improve the comprehensive care of brain tumor patients.

Bio:
Dr. Todd Hollon is a neurosurgeon and research scientist who specializes in brain tumors. He is an Assistant Professor of Neurosurgery. He completed his postdoctoral training in the UM Translational Molecular Imaging Laboratory under the supervision of Drs. Daniel Orringer and Honglak Lee. His postdoctoral work focused on the application of deep neural networks to advanced imaging methods to improve the speed and accuracy of intraoperative brain tumor diagnosis. He hopes to be part of the next generation of young scientists that uses computation and machine learning to make scientific breakthroughs.

Host: Josh Welch, PhD

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

In-Person: Forum Hall, Palmer Commons

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Livestream / Virtual Thu, 14 Oct 2021 14:26:31 -0400 2021-10-27T16:00:00-04:00 2021-10-27T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
STEM Research Career Award (October 27, 2021 4:00pm) https://events.umich.edu/event/87133 87133-21639078@events.umich.edu Event Begins: Wednesday, October 27, 2021 4:00pm
Location: Off Campus Location
Organized By: Office of National Scholarships & Fellowships (ONSF)

Register here: https://myumi.ch/O4eKQ

The U-M STEM Research Career Award supports highly qualified students who plan to pursue a PhD and research career in a STEM field.

The scholarship provides $5000 for summer research or other academic expenses. The scholarship does not require US citizenship; it is open to students from all nationalities and backgrounds. The U-M STEM Research Career Award application and letters of recommendation will also be used to select U-M’s nominees for the Goldwater and Astronaut Scholarships from among eligible applicants.

Learn more: https://lsa.umich.edu/onsf/scholarships/stem-biomedical/u-m-stem-research-career-award.html

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Livestream / Virtual Tue, 19 Oct 2021 13:30:18 -0400 2021-10-27T16:00:00-04:00 2021-10-27T17:00:00-04:00 Off Campus Location Office of National Scholarships & Fellowships (ONSF) Livestream / Virtual Chemical engineers develop clean energy storage solutions
Interdisciplinary QC/CM Seminar | Discrete Descriptions of Mechanical Metamaterials: from Spin Glass to Spin Ice (October 28, 2021 10:00am) https://events.umich.edu/event/86562 86562-21634899@events.umich.edu Event Begins: Thursday, October 28, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Physics

Zoom link:
https://tau-ac-il.zoom.us/j/91341585214?pwd=ZUU4K2FaN0tQbE11N3ZOZEpzbHJLdz09

Metamaterials are artificial structures made of arrays of multiple building blocks of mesoscopic length scales. For many mechanical metamaterials, the possible geometric states of each building block may be linked to discrete spin states of a magnetic system. I will show how designing the building blocks and their mutual spatial arrangement in a metamaterial enables much flexibility in setting the interactions in the corresponding spin system. This control of the frustration and the topological features of the spin system leads to novel functionalities such as response to predefined mechanical textures, spatial steering of stress and deformation fields, and multiple coexisting steady states.

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Workshop / Seminar Thu, 28 Oct 2021 18:16:12 -0400 2021-10-28T10:00:00-04:00 2021-10-28T11:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Astronomy Colloquium Series Presents: (October 28, 2021 3:30pm) https://events.umich.edu/event/88714 88714-21656960@events.umich.edu Event Begins: Thursday, October 28, 2021 3:30pm
Location: Michigan League
Organized By: Department of Astronomy

Unveiling Planet Formation in the Youngest Disks

The recent high-resolution imaging of protoplanetary disks by ALMA has demonstrated that substructures, most frequently in the form of narrow rings and gaps, in disks appear to be ubiquitous by ages of 1-10 Myr. This surprising development suggests that planet formation may begin earlier than previously expected, at times <1 Myr, while star and disk are still in their infancy. In this talk, I will discuss my ongoing work to characterize the state of planet formation in these young disks. This includes, in particular, efforts to study the bulk demographics (such as mass and size) of embedded disks through radiative transfer modeling of a sample of ~100 young disks as a part of the VANDAM: Orion Survey to understand the initial conditions present in disks for planet formation. I will also discuss my work to characterize the substructures present in these young disks that may indicate planet formation could be quite advanced, even in the youngest disks.

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Lecture / Discussion Wed, 27 Oct 2021 14:49:06 -0400 2021-10-28T15:30:00-04:00 2021-10-28T17:00:00-04:00 Michigan League Department of Astronomy Lecture / Discussion
Chanda Prescod-Weinstein: A Journey into Dark Matter, Spacetime, and Dreams Deferred (October 29, 2021 12:00pm) https://events.umich.edu/event/85788 85788-21629001@events.umich.edu Event Begins: Friday, October 29, 2021 12:00pm
Location: Off Campus Location
Organized By: Poverty Solutions

Chanda Prescod-Weinstein is an assistant professor of physics and a core faculty member for women’s studies at the University of New Hampshire. She will discuss her book, “The Disordered Cosmos: A Journey into Dark Matter, Spacetime, and Dreams Deferred,” which urges recognition of how science is rife with racism, sexism, and other dehumanizing systems and lays out a bold new approach to science and society.

The virtual conversation is free and open to the public, and U-M students can participate as part of a one-credit course, SWK 503 Section 001. This event is part of the annual Real-World Perspectives on Poverty Solutions fall speaker series, which introduces key issues regarding the causes and consequences of poverty featuring experts in policy and practice from across the nation, with the goal of encouraging the formation of a broad community of learners to engage in these issues together.

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Livestream / Virtual Wed, 08 Sep 2021 06:42:54 -0400 2021-10-29T12:00:00-04:00 2021-10-29T13:00:00-04:00 Off Campus Location Poverty Solutions Livestream / Virtual Real-World Perspectives on Poverty Solutions 2021 speaker series
HEP-Astro Seminar | Results From T2K and the Current Landscape of Neutrino Oscillation (November 1, 2021 4:00pm) https://events.umich.edu/event/86658 86658-21635382@events.umich.edu Event Begins: Monday, November 1, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Neutrinos are a tiny subatomic particle with surprising properties under active study. In particular, neutrinos oscillate, that is, they convert from one type of neutrino to another, is a surprising phenomenon under active study. The origin of neutrino mass is important for astrophysics, cosmology and particle physics, and many open questions surrounding neutrino oscillation exist. The Tokai-to-Kamioka (T2K) neutrino oscillation experiment sends a beam of muon flavor neutrinos or antineutrinos 295km across Japan. This seminar will discuss the state of the field of neutrino oscillation physics, including recent results from T2K, and T2K's exciting future program.

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Workshop / Seminar Mon, 01 Nov 2021 18:15:51 -0400 2021-11-01T16:00:00-04:00 2021-11-01T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
CM-AMO Seminar | Optical Magnetometry: Quantum Sensing and Absolute Magnetometry Challenges the Standard Model (November 2, 2021 4:00pm) https://events.umich.edu/event/86563 86563-21634900@events.umich.edu Event Begins: Tuesday, November 2, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Join Zoom Meeting
https://umich.zoom.us/j/92296304951
Meeting ID: 922 9630 4951
Passcode: 665739

Sensitive and accurate detection of time dependent magnetic fields has myriad applications from fundamental physics to astronomy to medicine to geophysics and, of course, to defense. Motivated by two experiments that challenge the Standard Model of Elementary particle physics, we have developed new approaches to magnetometry using optically pumped 3He applied from Tesla to microTesla. For the recently announced new measurement of the muon magnetic moment anomaly at Fermilab, an absolute 3He NMR magnetometer accurate to 30 ppb was introduced into the calibration chain of the 1.45 T magnetic field of the storage ring. For experiments under development to extend sensitivity to the neutron electric dipole moment, 3He magnetometers provide "read out" by micro-fabricated rubidium optical magnetometers. I'll describe the motivations and our continuing efforts to develop and improve these sensors.

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Workshop / Seminar Tue, 02 Nov 2021 18:16:15 -0400 2021-11-02T16:00:00-04:00 2021-11-02T17:00:00-04:00 West Hall Department of Physics Workshop / Seminar West Hall
MIPSE Seminar | Physics Impacts to Plasma Wave Thruster Design (November 3, 2021 3:30pm) https://events.umich.edu/event/86296 86296-21632604@events.umich.edu Event Begins: Wednesday, November 3, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The allure of electrodeless, rf based thrusters is fairly obvious in the abstract: long life due to no electrode sputtering, multi-propellant operation (in some cases), higher plasma density. Examples include capacitive, inductive, and wave-based thrusters. Generally, the fundamental application of these concepts is an rf heated plasma, expanded through a divergent magnetic nozzle. When a wave is proposed as the plasma generation mechanism, certain physical parameters are proscribed by the dispersion relation, which serves to relate plasma parameters to the thruster design. Some considerations of these impacts on plasma sources can be examined in basic models of the wave dispersion, absorption, and coupling. The conservation laws in these sources provide additional constraints. The interaction of these phenomena will be discussed from a modeling and experimental perspective for a helicon source in terms of the scaling of density with power, geometry, and coupling, with implications for wave-based thrusters.

About the Speaker:
Dr. James Gilland is a Senior Scientist at the Ohio Aerospace Institute, specializing in advanced plasma propulsion (300 W to 300 MW), including Hall thrusters (HTs), magnetoplasmadynamic thrusters, and plasma wave thrusters. He currently supports NASA Solar Electric Propulsion HT development for the NASA Gateway. Dr. Gilland has performed system and mission analyses of a range of nuclear and solar electric propulsion systems; and served as the Lead Nuclear Electric Propulsion (NEP) Engineer in NASA’s Nuclear Propulsion Office, performing analysis of multimegawatt NEP power and propulsion systems for human space exploration. He is a past NASA Innovative and Advanced Concepts Fellow for his work on propellantless propulsion using Alfven plasma waves. He served on the NASEM panel for Space Nuclear Propulsion Technologies in 2020, and on several NASA advisory panels, including the High Energy Power & Propulsion Capabilities Roadmap Team. Dr. Gilland has an MS in Aerospace Engr. from Princeton U. and a PhD in Nuclear Engr. & Engr. Physics from U. of Wisconsin.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:36:48 -0400 2021-11-03T15:30:00-04:00 2021-11-03T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Dr. James Gilland
Department Colloquium | The Search for Physics Beyond the Standard Model (November 3, 2021 4:00pm) https://events.umich.edu/event/87160 87160-21639220@events.umich.edu Event Begins: Wednesday, November 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link: https://umich.zoom.us/j/94692610056

The LHC has been spectacularly successful at verifying the predictions of the Standard Model of particle physics. Nonetheless, particle physicists dream of uncovering explanations for the pattern of fermion masses, the nature of dark matter, the hierarchy between the Planck scale and the weak scale, along with many other unexplained mysteries. In this talk, I will discuss the theoretical motivations for Beyond the Standard Model physics and prospects for discovery. I will emphasize the use of precision measurements as a tool for learning about unknown high scale physics.

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Workshop / Seminar Wed, 03 Nov 2021 18:15:51 -0400 2021-11-03T16:00:00-04:00 2021-11-03T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Department of Computational Medicine & Bioinformatics Weekly Seminar (November 3, 2021 4:00pm) https://events.umich.edu/event/88449 88449-21654119@events.umich.edu Event Begins: Wednesday, November 3, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract
My research group works in the area of mathematical oncology, where we use mathematical models to decipher the complex networks of reactions inside of cancer cells and interactions between cells. Immune cells use hundreds of biochemical reactions to respond to their environment, become activated, and kill cancer cells. Understanding the complexity of these reaction networks requires computational tools and mathematical models. We combine detailed, mechanistic modeling with machine learning to study these networks, better understand cancer and immune cells, and predict ways to control tumor growth. In this talk, I will present our recent work aimed at predicting the dynamics of immune cell behaviors across three scales: intracellular signaling pathways in CAR T cells, the collective behavior of a heterogeneous population of immune cells, and tumor-immune interactions at the tissue scale. Our models generate novel mechanistic insight into immune cell activation and predict the effects of immunotherapeutic strategies.


Biography
Stacey D. Finley is the Gordon S. Marshall Early Career Chair and Associate Professor of Biomedical Engineering at the University of Southern California. Dr. Finley received her B.S. in Chemical Engineering from Florida A & M University and obtained her Ph.D. in Chemical Engineering from Northwestern University. She completed postdoctoral training at Johns Hopkins University in the Department of Biomedical Engineering. Dr. Finley joined the faculty at USC in 2013, and she leads the Computational Systems Biology Laboratory. Dr. Finley has joint appointments in the Departments of Chemical Engineering and Materials Science and Quantitative and Computational Biology, and she is a member of the USC Norris Comprehensive Cancer Center. Dr. Finley is also the Founding Director of the Center for Computational Modeling of Cancer at USC. Her research is supported by grants from NSF, NIH, and the American Cancer Society.

Selected honors. 2016 NSF Faculty Early CAREER Award; 2016 Young Innovator by the Cellular and Molecular Bioengineering journal; Leah Edelstein-Keshet Prize from the Society of Mathematical Biology; Junior Research Award from the USC Viterbi School of Engineering; the Hanna Reisler Mentorship Award; 2018 AACR NextGen Star; 2018 Orange County Engineering Council Outstanding Young Engineer; Elected Fellow of the American Institute for Medical and Biological Engineering (2021)

Hosted by: Alan Boyle, PhD

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 20 Oct 2021 09:54:50 -0400 2021-11-03T16:00:00-04:00 2021-11-03T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Stacey D. Finley, Ph.D. (USC)
MCAIM Colloquium - Uncovering the Rules of Crumpling with a Data-Driven Approach (November 3, 2021 4:00pm) https://events.umich.edu/event/88366 88366-21653515@events.umich.edu Event Begins: Wednesday, November 3, 2021 4:00pm
Location: East Hall
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

When a sheet of paper is crumpled, it spontaneously develops a network of creases. Despite the apparent disorder of this process, statistical properties of crumpled sheets exhibit striking reproducibility. Recent experiments have shown that when a sheet is repeatedly crumpled, the total crease length grows logarithmically [1]. This talk will offer insight into this surprising result by developing a correspondence between crumpling and fragmentation processes. We show how crumpling can be viewed as fragmenting the sheet into flat facets that are outlined by the creases, and we use this model to reproduce the characteristic logarithmic scaling of total crease length, thereby supplying a missing physical basis for the observed phenomenon [2].

This study was made possible by large-scale data analysis of crease networks from crumpling experiments. We will describe recent work to use the same data with machine learning methods to probe the physical rules governing crumpling. We will look at how augmenting experimental data with synthetically generated data can improve predictive power and provide physical insight [3].

[1] O. Gottesman et al., Commun. Phys. 1, 70 (2018).
[2] J. Andrejevic et al., Nat. Commun. 12, 1470 (2021).
[3] J. Hoffmann et al., Sci. Advances 5, eaau6792 (2019)

Join us in person or on Zoom:
https://umich.zoom.us/j/95889337803
Meeting ID: 958 8933 7803 Passcode: 811977

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Workshop / Seminar Mon, 18 Oct 2021 14:10:34 -0400 2021-11-03T16:00:00-04:00 2021-11-03T17:00:00-04:00 East Hall Michigan Center for Applied and Interdisciplinary Mathematics Workshop / Seminar Chris Rycroft, Harvard University
An electrical engineer’s guide to research and development at Corning Incorporated (November 4, 2021 3:00pm) https://events.umich.edu/event/88126 88126-21650406@events.umich.edu Event Begins: Thursday, November 4, 2021 3:00pm
Location: Electrical Engineering and Computer Science Building
Organized By: Electrical and Computer Engineering

Dr. Donnell Walton is the 2021 ECE Willie Hobbs Moore Alumni Lectureship recipient.

Abstract

I will discuss the past, present and future of electrical-engineering-related research at Corning Incorporated. I will overview Corning’s historical industry-defining contributions in areas comprising light bulbs, vacuum tubes and cathode ray tubes.I will provide an overview of our current work in wireless networks for autonomous vehicles, adaptive optics and electronics for active optical couplers, and novel materials for high-frequency printed circuit boards. I will conclude the talk with some ruminations and lessons on industrial research.

Bio

Dr. Donnell Walton is the director of the Corning Technology Center Silicon Valley. In this role, he leads research and business development efforts to match Corning’s existing and emerging capabilities and opportunities in the western United States, in particular, the Silicon Valley region of California.

Walton joined Corning in 1999 as a senior research scientist in Science & Technology, where he performed and led research in optical fiber amplifiers and lasers. In 2004, Walton led Corning’s research and development efforts to a world leadership position in high-power (kW) fiber lasers. Then in 2006, he managed the Silicon on Glass (SiOG) platform expansion project, which demonstrated non-display applications of SiOG including imagers and photovoltaics. In 2008, Walton joined the Corning® Gorilla® Glass team as a senior applications engineer, where he extended the Gorilla Glass value proposition to form factors larger than handheld devices. In 2010, Walton was appointed manager of worldwide applications engineering for Gorilla Glass.

Prior to joining Corning, Walton was a physics professor at Howard University in Washington, D.C., where he won the National Science Foundation’s Young Investigator (CAREER) Award.

Walton earned a Ph.D. in applied physics from the University of Michigan, Ann Arbor after graduating summa cum laude with bachelor’s degrees in physics and electrical engineering from North Carolina State University. He completed the Stanford Executive Program at the Graduate School of Business in 2019. He serves on the board of the National Society of Black Physicists, the research advisory board of the IBM-HBCU Quantum Center and the corporate affiliate boards at the Universities of California in Santa Barbara and San Diego. Walton has authored or co-authored 22 U.S. patents and more than 60 technical reports.

The ECE Dr. Willie Hobbs Moore Alumni Lecture is given by ECE alumni from traditionally underrepresented groups in Electrical and Computer Engineering who are leaders in their field and serve as role models for the ECE community through their leadership, impact on society, service to the community, or other contributions.

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Lecture / Discussion Mon, 11 Oct 2021 20:14:32 -0400 2021-11-04T15:00:00-04:00 2021-11-04T16:00:00-04:00 Electrical Engineering and Computer Science Building Electrical and Computer Engineering Lecture / Discussion speaker headshot
Astronomy Colloquium Series Presents: (November 4, 2021 3:30pm) https://events.umich.edu/event/88717 88717-21656966@events.umich.edu Event Begins: Thursday, November 4, 2021 3:30pm
Location: Michigan League
Organized By: Department of Astronomy

Title and abstract coming soon

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Lecture / Discussion Wed, 27 Oct 2021 14:51:49 -0400 2021-11-04T15:30:00-04:00 2021-11-04T17:00:00-04:00 Michigan League Department of Astronomy Lecture / Discussion
"Cell cycle regulation in microbes" (November 4, 2021 4:00pm) https://events.umich.edu/event/88883 88883-21658814@events.umich.edu Event Begins: Thursday, November 4, 2021 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

BME 500 Seminar Series
Ariel Amir, Ph.D.
Applied Mathematics and Physics
Harvard University

"Cell cycle regulation in microbes"

Abstract:
Microbial cells are remarkable in their abilities to adapt to different environments while maintaining cellular homeostasis. How cells coordinate the various events within the cell cycle, notably cell division and DNA replication, remains an outstanding problem for cells of all domains of life. I will discuss our current understanding of cell cycle regulation in microbes, including recent results demonstrating a tight coupling between DNA replication and cell division in E. coli.

DATE: Thursday, November 4, 2021
TIME: 4:00-5:00 pm
ZOOM LINK: https://umich.zoom.us/j/97723483179

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Presentation Tue, 02 Nov 2021 09:04:43 -0400 2021-11-04T16:00:00-04:00 2021-11-04T17:00:00-04:00 Off Campus Location Biomedical Engineering Presentation BME Logo
Interdisciplinary QC/CM Seminar | Electrically Charged Skyrmions: Theory and Practice (November 4, 2021 4:00pm) https://events.umich.edu/event/86564 86564-21634901@events.umich.edu Event Begins: Thursday, November 4, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Link for the seminar: https://umich.zoom.us/j/95097563417
Topic: QC/CM Seminar Virtual - Nov 4
Time: Nov 4, 2021 04:00 PM America/Detroit
Join Zoom Meeting
https://umich.zoom.us/j/95097563417
Meeting ID: 950 9756 3417

Skyrmions, first proposed in the context of nuclear physics, have since found many applications to the solid state in the form of topological textures in a material’s magnetic order. When skyrmions arise in systems with band topology, Berry-phase effects can endow them with an electric charge in addition to their magnetic moment, with important implications for electrical transport. I’ll start by highlighting recent experimental work using scanning tunneling microscopy to “image” charged valley skyrmions in the quantum Hall states of graphene. I’ll then discuss how skyrmions may arise in magic angle twisted bilayer graphene. In this system skyrmions are predicted to be charge-2 bosons which may Bose condense, potentially giving a new route to electron-mediated superconductivity.

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Workshop / Seminar Thu, 04 Nov 2021 18:15:51 -0400 2021-11-04T16:00:00-04:00 2021-11-04T17:00:00-04:00 Off Campus Location Department of Physics Workshop / Seminar
Professor Jianming Qian, The David M. Dennison Collegiate Professorship in Physics, Inaugural Lecture (November 4, 2021 4:00pm) https://events.umich.edu/event/84263 84263-21620829@events.umich.edu Event Begins: Thursday, November 4, 2021 4:00pm
Location: Weiser Hall
Organized By: The College of Literature, Science, and the Arts

The Standard Model of particle physics has been remarkably successful in describing phenomena at the smallest distances that are explorable with current technologies. Discoveries over the last half-century at the energy frontier, enabled by powerful accelerators, are imperative in the development of the Standard Model. In this presentation, I will discuss research and major discoveries which I have been fortunate to be part of.

If you are unable to join us in person, please click the link below to join the webinar:
https://umich.zoom.us/j/99033828701
Or One tap mobile :
US: +13126266799,,99033828701# or +16468769923,,99033828701#
Or Telephone:
Dial(for higher quality, dial a number based on your current location):
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Webinar ID: 990 3382 8701
International numbers available: https://umich.zoom.us/u/anBcTbOob

Or an H.323/SIP room system:
H.323:
162.255.37.11 (US West)
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Meeting ID: 990 3382 8701
SIP: 99033828701@zoomcrc.com

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Lecture / Discussion Thu, 21 Oct 2021 13:55:52 -0400 2021-11-04T16:00:00-04:00 2021-11-04T17:00:00-04:00 Weiser Hall The College of Literature, Science, and the Arts Lecture / Discussion Poster Image
HET Seminar | Continuum Dark Matter (November 5, 2021 3:00pm) https://events.umich.edu/event/88298 88298-21652128@events.umich.edu Event Begins: Friday, November 5, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The microscopic nature of dark matter remains a major outstanding question in particle physics and cosmology, and many simple models are now in tension with experimental constraints such as direct detection bounds. In this talk, I will introduce the notion of “gapped continuum” in quantum field theories, and explain how it can be realized explicitly by a field propagating on a 5D warped space background with a soft wall. I will then describe how to calculate cross sections and decay rates involving gapped continuum states, as well as study their equilibrium and non-equilibrium thermodynamics. With this theoretical framework in hand, I will present a fully realistic model of dark matter consisting of gapped continuum states, interacting with the Standard Model via the Z portal. Direct detection bounds, which normally rule out Z portal interactions for thermal-relic dark matter, are avoided due to a strong suppression of the relevant cross sections by a mechanism peculiar to gapped continuum. Some interesting and potentially testable predictions of this model, such as continuous decays of the dark matter states throughout the history of the universe, as well as striking collider signatures, will also be discussed.

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Lecture / Discussion Thu, 14 Oct 2021 19:20:42 -0400 2021-11-05T15:00:00-04:00 2021-11-05T16:00:00-04:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
Saturday Morning Physics | On Deciding the Next Big Science Experiments (November 6, 2021 10:30am) https://events.umich.edu/event/85694 85694-21628290@events.umich.edu Event Begins: Saturday, November 6, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

The advancement of science requires decommissioning old experiments and pursuing new experiments. But which new experiments? How should we decide? Professor Wells will show answering these questions necessarily goes well beyond scientific considerations and lays bare philosophical, economic, and political viewpoints. He will illustrate these principles in action for large-scale experiments such as particle colliders, nuclear research reactors, and missile defense tests.

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Livestream / Virtual Mon, 01 Nov 2021 09:33:01 -0400 2021-11-06T10:30:00-04:00 2021-11-06T11:30:00-04:00 Off Campus Location Saturday Morning Physics Livestream / Virtual
RNA Innovation Seminar (November 8, 2021 4:00pm) https://events.umich.edu/event/86167 86167-21631759@events.umich.edu Event Begins: Monday, November 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Center for RNA Biomedicine

"Harnessing diverse compact CRISPR-Cas3 for long-range genome engineering"
Zhonggang Hou, Ph.D.
Research Investigator
Biological Chemistry

and

"Microscopic Examination of Spatial Transcriptome through Seq-Scope"
Jun Hee Lee, PhD
Associate Professor
Molecular & Integrative Physiology

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Lecture / Discussion Mon, 25 Oct 2021 13:33:17 -0400 2021-11-08T16:00:00-05:00 2021-11-08T20:00:00-05:00 Off Campus Location Center for RNA Biomedicine Lecture / Discussion Zhonggang Hou, Biological Chemistry & Jun Hee Lee, Molecular & Integrative Physiology
Complex System Virtual Seminar | Using Information Geometry to Find Simple Models of Complex Processes" (November 9, 2021 11:30am) https://events.umich.edu/event/88702 88702-21656854@events.umich.edu Event Begins: Tuesday, November 9, 2021 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

ZOOM MEETING
https://umich.zoom.us/j/96616169868
Passcode: CSCS

ABSTRACT: Effective theories play a fundamental role in how we reason about the world. Although real physical processes are very complicated, useful models abstract away the irrelevant degrees of freedom to give parsimonious representations. I use information geometry to construct simplified models for many types of complex systems, such as biology, neuroscience, statistical physics, and complex engineered systems. I interpret a multi-parameter model as a manifold embedded in the space of all possible data, with a metric induced by statistical distance. These manifolds are often bounded and very thin, so they are well-approximated by a low-dimensional, simple model. For many types of models, there is a hierarchy of natural approximations that reside on the manifold's boundary. These approximations are not black-boxes. They remain expressed in terms of the relevant combinations of mechanistic parameters and reflect the physical principles on which the complicated model was built. They can also be constructed in a systematic way using computational differential geometry.

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Workshop / Seminar Tue, 02 Nov 2021 14:45:27 -0400 2021-11-09T11:30:00-05:00 2021-11-09T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Workshop / Seminar Mark Transtrum
HET Brown Bag Seminar | Modular forms and zeta-values in string amplitudes (November 9, 2021 11:30am) https://events.umich.edu/event/88953 88953-21659252@events.umich.edu Event Begins: Tuesday, November 9, 2021 11:30am
Location: Randall Laboratory
Organized By: Leinweber Center for Theoretical Physics

Several rich mathematical objects appear in superstring scattering amplitudes, such as modular graph forms and Riemann zeta-values. Modular graph forms are modular forms associated with vacuum Feynman graphs. Both modular graph forms and zeta-values admit a grading by their transcendental weight. I shall review the transcendental structure of superstring amplitudes, including the conjectured uniform transcendentality of genus-one amplitudes in Type II superstring theory. I shall also describe recent work with Eric D’Hoker (arXiv:2110.06237) in which we evaluated the integrals of several infinite families of modular graph functions over genus-one moduli space.

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Lecture / Discussion Thu, 04 Nov 2021 05:10:02 -0400 2021-11-09T11:30:00-05:00 2021-11-09T12:30:00-05:00 Randall Laboratory Leinweber Center for Theoretical Physics Lecture / Discussion Randall Laboratory
CM-AMO Seminar | Realizing the Kitaev Limit in New Generation Honeycomb Iridates (November 9, 2021 4:00pm) https://events.umich.edu/event/86565 86565-21634902@events.umich.edu Event Begins: Tuesday, November 9, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Materials composed of d5 magnetic atoms in a strong octahedral crystal field and large spin-orbit coupling host Heisenberg and pseudo-dipolar interactions, but also unconventional spatially anisotropic magnetic interactions. Of particular interest are Ir 4+ with a network of edge-sharing IrO_6 octahedra arranged in a honeycomb lattice, for example, α-Li_2IrO_3 and NaIrO_3, in which strong Kitaev interactions are present. Recently, aiming to modify the magnetic interactions in these compounds towards the Kitaev Quantum Spin Liquid limit, new honeycomb iridates Ag_3LiIr_2O_6 and H_3LiIr_2O_6, have been synthesized by introducing alternative atomic species between the IrO layers. I will present resonant x-ray spectroscopy measurements in these two new-generation honeycomb iridates. Motivated by recent proposals of using coherent light-matter interaction to nudge these materials towards the Kitaev QSL, I will also discuss time-resolved optical polarimetry and time-resolved resonant techniques as probes for competing magnetic phases far from equilibrium.

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Workshop / Seminar Tue, 09 Nov 2021 18:15:49 -0500 2021-11-09T16:00:00-05:00 2021-11-09T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
HEP-Astro Seminar | The Future Circular Collider (FCC) Feasibility Study and Its Physics Potential (November 9, 2021 4:00pm) https://events.umich.edu/event/86497 86497-21634736@events.umich.edu Event Begins: Tuesday, November 9, 2021 4:00pm
Location: Randall Laboratory
Organized By: Department of Physics

The European Strategy in Particle Physics, has put an e+e- factory as first priority and recommended that Europe, together with its international partners, should investigate the technical and financial feasibility of a future hadron collider at CERN with a centre-of-mass energy of at least 100 TeV, and with an electron-positron Higgs and electroweak factory as a possible first stage. Such a feasibility study of the colliders should be completed on the timescale of the next Strategy update. We present in this seminar the FCC feasibility study goals, and the FCC physics potential, in particular for the FCC-ee possible first step, which is seen by many as necessary to optimize the FCC physics case and to cover in the best way in the foreseeable future the Higgs, Electroweak and Top physics up to 365 GeV in the center of mass.

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Workshop / Seminar Tue, 09 Nov 2021 18:15:50 -0500 2021-11-09T16:00:00-05:00 2021-11-09T17:00:00-05:00 Randall Laboratory Department of Physics Workshop / Seminar Randall Laboratory
Department of Computational Medicine & Bioinformatics Weekly Seminar (November 10, 2021 4:00pm) https://events.umich.edu/event/88540 88540-21654960@events.umich.edu Event Begins: Wednesday, November 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Subspace classifiers have been around for a long time, beginning with feature selection, which in essence was a subspace selection technique. This talk will discuss the kind of subspace classifiers that Bledsoe and Browning presented in their 1959 paper and from which there have been a variety of extensions which we will discuss.

The Bledsoe and Browning subspace classifier quantizes measurement space. Each quantized observation tuple corresponds to a cell in measurement space. A collection of subspaces are selected at random. In the original form the subspaces were mutually exclusive. For each class, each cell of a subspace contained a number dependent on the number of observations of the training data that fell into that cell. For each class those numbers were combined in ways not dissimilar to random forests. For a given observation tuple, the class with the highest vote count was selected as the assigned class.

We will discuss a variety of principled extensions of the technique and make some comparisons with Neural Networks.

Research Interests:

High-dimensional space clustering, pattern recognition, knowledge discovery and artificial intelligence

Professor Haralick began his work as one of the principal investigators of the NASA ERTS satellite data doing remote sensing image analysis.

He has made a series of contributions in the field of computer vision. In the high-level vision area, he has worked on inferring 3D geometry from one or more perspective projection views.] He has also identified a variety of vision problems which are special cases of the consistent labeling problem. His papers on consistent labeling, arrangements, relation homomorphism, matching, and tree search translate some specific computer vision problems to the more general combinatorial consistent labeling problem and then discuss the theory of the look-ahead operators that speed up the tree search. The most basic of these is called Forward Checking. This gives a framework for the control structure required in high-level vision problems. He has also extended the forward-checking tree search technique to propositional logic.

Zoom: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 22 Oct 2021 09:28:27 -0400 2021-11-10T16:00:00-05:00 2021-11-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Robert M. Haralick, PhD (City University of New York)
MCAIM Colloquium - Hydrodynamic Stability at High Reynolds Number (November 10, 2021 4:00pm) https://events.umich.edu/event/88932 88932-21659127@events.umich.edu Event Begins: Wednesday, November 10, 2021 4:00pm
Location: East Hall
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

The stability of equilibria solutions of the incompressible Euler and Navier-Stokes equations at high Reynolds number has been studied since the 1800s with the work of Kelvin, Rayleigh, Reynolds and others. However, only in recent years have we started to get a firm mathematical understanding of this field, even for the deceptively simple case of shear flows and vortices. I will outline some of the many recent advances in the area, including inviscid damping, enhanced dissipation, subcritical transition, vortex axi-symmetrization, and the local well-posedness of vortex filaments.

Join us in person or on Zoom:
https://umich.zoom.us/j/95889337803
Meeting ID: 958 8933 7803 Passcode: 811977

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Lecture / Discussion Wed, 03 Nov 2021 14:12:41 -0400 2021-11-10T16:00:00-05:00 2021-11-10T17:00:00-05:00 East Hall Michigan Center for Applied and Interdisciplinary Mathematics Lecture / Discussion Jacob Bedrossian, University of Maryland
Astronomy Colloquium Series Presents: (November 11, 2021 3:30pm) https://events.umich.edu/event/88718 88718-21656967@events.umich.edu Event Begins: Thursday, November 11, 2021 3:30pm
Location: Michigan League
Organized By: Department of Astronomy

Title and abstract coming soon

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Lecture / Discussion Wed, 27 Oct 2021 14:53:59 -0400 2021-11-11T15:30:00-05:00 2021-11-11T17:00:00-05:00 Michigan League Department of Astronomy Lecture / Discussion
Interdisciplinary QC/CM Seminar | The Grasshopper Problem (November 11, 2021 4:00pm) https://events.umich.edu/event/86566 86566-21634903@events.umich.edu Event Begins: Thursday, November 11, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

A grasshopper lands at a random point on a planar lawn of area one. It then makes one jump of fixed distance d in a random direction. What shape should the lawn be to maximize the chance that the grasshopper remains on the lawn after jumping? This easily stated yet hard to solve mathematical problem has intriguing connections to quantum information and statistical physics. A generalized version on the sphere can provide insight into a new class of Bell inequalities. A discrete version can be modeled by a spin system, representing a new class of statistical models with fixed-range interactions, where the range d can be large. I will show that, perhaps surprisingly, there is no d > 0 for which a disc shaped lawn is optimal. If the jump distance is smaller than the radius of the unit disc, the optimal lawn resembles a cogwheel, with transitions to more complex, disconnected shapes at larger d. Using parallel tempering Monte Carlo for the discrete spin model, several classes of optimal lawn shapes with different symmetry properties can be identified.


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Workshop / Seminar Thu, 11 Nov 2021 18:15:45 -0500 2021-11-11T16:00:00-05:00 2021-11-11T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
HET Seminar | Confining or Not? (November 12, 2021 3:00pm) https://events.umich.edu/event/88513 88513-21654663@events.umich.edu Event Begins: Friday, November 12, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The problem of Color Confinement in Yang-Mills theory is one of the deepest problems in theoretical physics. There is convincing numerical evidence from Lattice Gauge Theory, yet the proof of Confinement in Asymptotically Free theories has not been found. I will briefly introduce the Confinement problem and review some results on large N theories using the gauge/gravity duality. I will then discuss two-dimensional SU(N) theory coupled to an adjoint Majorana fermion. I will show that, when the adjoint mass is sent to zero, the spectrum retains a mass gap but the confinement disappears. Using the Discretized Light-Cone Quantization, I will discuss the spectrum of color singlet states and exhibit certain threshold states. Similar threshold states are also present in a model with a massless adjoint and a massive fundamental fermion. They provide new evidence for the lack of confinement. When the adjoint mass is turned on, the theory becomes confining, and the spectrum of bound states becomes discrete.

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Lecture / Discussion Thu, 21 Oct 2021 13:10:30 -0400 2021-11-12T15:00:00-05:00 2021-11-12T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
HEP-Astro Seminar | MicroBooNE's First Results: Addressing a 5sigma Anomaly with a Precision Detector (November 15, 2021 4:00pm) https://events.umich.edu/event/86498 86498-21634737@events.umich.edu Event Begins: Monday, November 15, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

I will present the first oscillation-related results from the MicroBooNE neutrino experiment at Fermilab. These measurements, featuring extensive searches for anomalous rates of both electron neutrinos and neutrino-induced gammas from the Booster Neutrino Beamline with multiple final-state topologies, directly address the 4.8sigma excess of electron-like events seen by the MiniBooNE experiment.

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Workshop / Seminar Mon, 15 Nov 2021 18:15:49 -0500 2021-11-15T16:00:00-05:00 2021-11-15T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
CM-AMO Seminar | Precision Spectroscopy of Rb 5D_{3/2} Atoms in an Optical Lattice (November 16, 2021 4:00pm) https://events.umich.edu/event/89185 89185-21660985@events.umich.edu Event Begins: Tuesday, November 16, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Practical applications of the 5DJ levels of Rb include their role in portable, vapor-cell atomic clocks [1] and the definition of the meter [2]. I will outline a recent experiment where simultaneous measurements of the 5D_{3/2} state’s dynamic polarizability and photoionization (PI) cross section at 1.064 μm are made using laser spectroscopy. In this experiment, cold ^{85}Rb atoms are trapped in a deep, 1.064-μm optical lattice of ~10^5 photon recoils and probed with two lasers scanning over the D1 and 5P_{1/2}-to-5D_{3/2} lines. Detection of the 5D_{3/2} population as a function of the laser detunings is achieved by collecting and counting photo-ions. This procedure yields a dynamic scalar polarizability of -524(17) atomic units and PI cross section of 44(1) Mb.

[1] Kyle W. Martin, Gretchen Phelps, Nathan D. Lemke, Matthew S. Bigelow, Benjamin Stuhl, Michael Wojcik, Michael Holt, Ian Coddington, Michael W. Bishop, and John H. Burke, Phys. Rev. Applied 9, 014019 (2018).
[2] T. J. Quinn, Metrologia 40, 103 (2003).

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Workshop / Seminar Tue, 16 Nov 2021 18:16:04 -0500 2021-11-16T16:00:00-05:00 2021-11-16T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
12th MIPSE Graduate Student Symposium (November 17, 2021 2:00pm) https://events.umich.edu/event/89170 89170-21660817@events.umich.edu Event Begins: Wednesday, November 17, 2021 2:00pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The 12th Annual MIPSE Graduate Student Symposium will be held in person. The symposium is an opportunity for students involved in plasma research to present the results of their investigations, learn about the research of their fellow students, and network with MIPSE faculty and staff.

The Symposium will feature a special MIPSE seminar and three student poster sessions. All student posters will be considered for the Best Presentation Award.

Schedule and details: https://mipse.umich.edu/symposium_2021.php

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Conference / Symposium Thu, 11 Nov 2021 11:03:20 -0500 2021-11-17T14:00:00-05:00 2021-11-17T19:00:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Conference / Symposium Electrical Engineering and Computer Science Building
MIPSE Seminar | The Plasma-Water Interface: Modern Challenges and New Software Tools (November 17, 2021 3:30pm) https://events.umich.edu/event/86297 86297-21632605@events.umich.edu Event Begins: Wednesday, November 17, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The interaction of low-temperature plasmas with liquid water is a fundamental problem in many applications, from plasma medicine to chemical processing, and more generally where the generation of reactive oxygen and nitrogen species and/or of solvated electrons is of utmost importance. However, characterization of the plasma-liquid interface presents several challenges, both experimentally and computationally, due to the multiscale and multiphysics nature of the problem. In this seminar we provide an overview of recent modeling developments on plasma-liquid interfaces, presenting the new software package Zapdos-CRANE, based on the MOOSE finite-element framework. We provide a brief overview of the software, showing few case studies of interest. The model was used to study a humid argon DC plasma over a water surface, operated in both cathodic and anodic modes. In this system, one of the reactions of interest is the formation and dissolution of hydroxide (OH) radicals, which subsequently produce hydrogen peroxide. The model allows the investigation of the main plasma-chemistry reaction mechanisms for peroxide production with the plasma. The analysis reveals that hydrogen peroxide is increased during anodic plasma treatment due to elevated water vapor dissociation reactions near the interface. Finally, the role of solvated electrons generated during cathodic plasma operations is discussed, showing how they directly degrade hydrogen peroxide in the aqueous phase, inhibiting its accumulation.

About the Speaker:
Davide Curreli is Associate Professor in the Department of Nuclear, Plasma, and Radiological Engineering at the University of Illinois Urbana-Champaign, and at the National Center for Supercomputing Applications. Dr. Curreli leads the Laboratory for Computational Plasma Physics at Illinois. His research activities focus on computational modeling of plasma material interactions and plasma chemistry of low-temperature plasmas for fusion and nuclear applications. Among his current research activities, Dr. Curreli is coordinator of the Nuclear Fireball Plasma Chemistry activities within the University Research Alliance funded by DOD DTRA. His group actively works on multiple projects in Fusion Energy Sciences. Dr. Curreli is Donald Biggar Willett Faculty Scholar at the University of Illinois.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:44:13 -0400 2021-11-17T15:30:00-05:00 2021-11-17T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Davide Curreli
DCMB / CCMB Weekly Seminar Series (November 17, 2021 4:00pm) https://events.umich.edu/event/89137 89137-21660643@events.umich.edu Event Begins: Wednesday, November 17, 2021 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk title: Clinical Trajectory analysis to determine risk-factors of Copd: A COPDGene Study

Abstract:

Background

Chronic obstructive pulmonary disease (COPD) presents significant clinical heterogeneity and a wide variety of progression trajectories [1]. Clinical trajectory analysis (ClinTrajAn) is a powerful tool based on elastic principal graphs for the calculation of trajectories from large cross-sectional clinical data sets [2].

Aims and objectives

Our objective was to determine potential risk-factors by evaluate progression trajectories in COPD using ClinTrajAn on the COPDGene Phase I (baseline visit) dataset.

Methods

7883 participants, current and former smokers with GOLD 0 thru 4 COPD, from Phase I of the COPDGene study, were utilized for this work. 55 features were obtained for each subject, including demographics, spirometry, smoking history and computed tomography (CT), which included Parametric Response Mapping (PRM). Developed by our group, PRM is capable of simultaneously measuring small airways disease and emphysema which are the main contributors of airflow limitations in COPD. The resulting data matrix was analyzed with ClinTrajAn.

Results

A principal tree, with 13 branch segments and 8 termini, was generated (Figure 1). There was a clearly recognized trajectory from healthier subjects through decreasing lung function and increasing age (Figure 1 A), increasing in GOLD (Figure 1 B), to an emphysema high terminus (Figure 1 C). Notably this method illustrated numerous branching points along this trajectory.

Conclusions

In this study we used ClinTrajAn to obtain a map of disease progression trajectories in COPD including clinically recognized pathogenesis. Our next steps will be to further validate this approach using longitudinal data from the COPDGene follow-up visits.

References

1. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, MacNee W, Make BJ. Chronic obstructive pulmonary disease phenotypes: the future of COPD. American journal of respiratory and critical care medicine. 2010 Sep 1;182(5):598-604.

2. Golovenkin SE, Bac J, Chervov A, Mirkes EM, Orlova YV, Barillot E, Gorban AN, Zinovyev A. Trajectories, bifurcations, and pseudo-time in large clinical datasets: applications to myocardial infarction and diabetes data. GigaScience. 2020 Nov;9(11):giaa128.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Wed, 10 Nov 2021 09:47:40 -0500 2021-11-17T16:00:00-05:00 2021-11-17T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Department Colloquium | Nonlinear Terahertz Spectroscopy and Terahertz Control of Material Structure and Dynamics (November 17, 2021 4:00pm) https://events.umich.edu/event/88805 88805-21658382@events.umich.edu Event Begins: Wednesday, November 17, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

https://umich.zoom.us/j/94692610056

The development of methods for generation of strong terahertz-frequency electromagnetic fields has enabled the advance of nonlinear THz spectroscopy and 2-dimensional THz spectroscopy of collective and molecular degrees of freedom. These methods have revealed multiple-quantum coherences and correlations among modes ranging from gas-phase molecular rotations to lattice vibrations (optical phonons) in quantum paraelectric crystals to spin waves (magnons) in canted antiferromagnetic systems. Recent results will be reviewed and will segue from nonlinear THz spectroscopy to nonlinear THz control over material structure and behavior. Structural and electronic phase transitions have been induced by THz fields, yielding transient or long-lived phases whose formation dynamics have been monitored using THz, optical, and x-ray probes. Finally, the prospects for excitation of multiple modes including acoustic and optical phonons, magnons, and low-frequency electronic responses in order to reveal their interactions and to guide materials through complex multiphase landscapes will be discussed.


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Workshop / Seminar Wed, 17 Nov 2021 18:15:45 -0500 2021-11-17T16:00:00-05:00 2021-11-17T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
Astronomy Colloquium Series Presents: (November 18, 2021 3:30pm) https://events.umich.edu/event/88719 88719-21656968@events.umich.edu Event Begins: Thursday, November 18, 2021 3:30pm
Location: Michigan League
Organized By: Department of Astronomy

Title and abstract coming soon

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Lecture / Discussion Wed, 27 Oct 2021 14:55:29 -0400 2021-11-18T15:30:00-05:00 2021-11-18T17:00:00-05:00 Michigan League Department of Astronomy Lecture / Discussion
Interdisciplinary QC/CM Seminar | Pulsed-Field Techniques Applied to UTe_2: High-Field Magnetism and the "Lazarus*" Superconducting State (November 18, 2021 4:00pm) https://events.umich.edu/event/86567 86567-21634904@events.umich.edu Event Begins: Thursday, November 18, 2021 4:00pm
Location: Mason Hall
Organized By: Department of Physics

High magnetic fields usually destroy superconductivity. However, this talk will describe a variety of measurements carried out in pulsed magnetic fields of up to 73 T, including transport, magnetometry, the magnetocaloric effect and MHz penetration depth, that show that UTe2 exhibits multiple high-field bulk superconducting phases. These include the highest magnetic field range of any re-entrant superconducting phase, with zero resistance persisting beyond 70 T. Despite the huge range of magnetic field involved, all of the superconducting phases vanish at a similar temperature.

Superconductivity in such high magnetic fields presents a considerable challenge for current theoretical approaches. Whilst models such as the Jaccarino-Peter compensation effect can be eliminated as an explanation, the magnetic-fluctuation-mediated superconductivity mechanism thought to occur in heavy-fermion compounds such as URhGe could provide a qualitative understanding of UTe_2. Finally, I discuss the "homogenizing" role of high magnetic fields in both UTe_2 and systems such as CeOs_4Sb_{12}. In these materials, the zero-field properties are highly sensitive to details of the synthesis method and crystal quality, whereas the phase diagrams are unified in fields above 30 T.

*In UTe_2 the superconductivity initially appears to be "killed" by the magnetic field. But then, like Lazarus, it "rises from the dead" at a higher field. Thanks are due to the NHMFL publicity department for this (possibly useful) analogy which has now entered popular physics culture.

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Workshop / Seminar Thu, 18 Nov 2021 18:15:50 -0500 2021-11-18T16:00:00-05:00 2021-11-18T17:00:00-05:00 Mason Hall Department of Physics Workshop / Seminar Mason Hall
HET Seminar | Lessons and surprises from Kaluza-Klein spectra (November 19, 2021 3:00pm) https://events.umich.edu/event/88952 88952-21659251@events.umich.edu Event Begins: Friday, November 19, 2021 3:00pm
Location: West Hall
Organized By: Leinweber Center for Theoretical Physics

Infinite towers of massive modes arise for every compactification of higher dimensional theories. Understanding the properties of these Kaluza-Klein towers on non-trivial solutions with an AdS factor has been a longstanding issue with clear holographic interest, as they describe the spectrum of single-trace operators of the dual CFTs at strong coupling and large N. In this talk, I will focus on two classes of solutions of such kind. The first class consists of AdS4 S-fold solutions of Type IIB supergravity that can be obtained from maximal gauged supergravity in D=4. For the later part, I will describe new families of solutions in N=(1,1) supergravity in D=6 which uplift from half-maximal supergravity in D=3. In both cases, the spectra can be computed using recent techniques from Exceptional Field Theory, and the information thus obtained leads to several unexpected conclusions.

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Lecture / Discussion Thu, 04 Nov 2021 05:05:02 -0400 2021-11-19T15:00:00-05:00 2021-11-19T16:00:00-05:00 West Hall Leinweber Center for Theoretical Physics Lecture / Discussion West Hall
Saturday Morning Physics | Physics of “The Bends” – The Mechanics Behind Decompression Sickness (November 20, 2021 10:30am) https://events.umich.edu/event/85698 85698-21628294@events.umich.edu Event Begins: Saturday, November 20, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

Decompression sickness is a disease that affects scuba divers when they ascend too rapidly from depth. It is caused by gas bubbles that form in the blood and tissue when the pressure drops. Professor Meiners will discuss the physics of gas bubble formation, their effects on our body with a special emphasis on the spinal cord, and how we can treat them.

Virtual YouTube Link: https://www.youtube.com/watch?v=542hb9f8BDs

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Livestream / Virtual Thu, 18 Nov 2021 15:13:39 -0500 2021-11-20T10:30:00-05:00 2021-11-20T11:30:00-05:00 Off Campus Location Saturday Morning Physics Livestream / Virtual Photo of Professor Meiners Scuba Diving
HEP-Astro Seminar | Millimeter Cosmology: Simons Observatory and CMB-S4 (November 29, 2021 4:00pm) https://events.umich.edu/event/86613 86613-21635220@events.umich.edu Event Begins: Monday, November 29, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link:
https://umich.zoom.us/j/91409362110?pwd=UDlja2FuYlZWVFNEMWFrOTlkWFNEZz09

Measurements of the millimeter wave sky provide a wealth of cosmological and astrophysical information. These measurements constrain primordial gravitational waves and inflation, provide new constraints on the dark universe, map the distribution of matter through gravitational lensing and the Sunyaev–Zeldovich effects, and measure the time varying millimeter wave sky. Simons Observatory and CMB-S4 represent the next two generations of cosmic microwave background observatories. In this talk I will give an overview of the science these projects will enable, present the instrument designs, and discuss the status of these projects.

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Workshop / Seminar Mon, 29 Nov 2021 18:15:49 -0500 2021-11-29T16:00:00-05:00 2021-11-29T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
MCAIM / MICDE Joint Sponsored Talk - Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts (November 30, 2021 10:00am) https://events.umich.edu/event/89601 89601-21664515@events.umich.edu Event Begins: Tuesday, November 30, 2021 10:00am
Location:
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

Speaker: James Stokes, Flatiron Institute, Simons Foundation

Title: Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts

Abstract: Stokes will review a family of variational algorithms which have been proposed as candidates to make use of near- to intermediate-term quantum computers, placing particular emphasis on geometric and numeric features that are shared by classical variational stochastic approximation algorithms. Stokes will also discuss some applications of this hybrid quantum-classical approach to scientific and engineering problems beyond its traditional domain of application.

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Lecture / Discussion Tue, 30 Nov 2021 10:06:11 -0500 2021-11-30T10:00:00-05:00 2021-11-30T11:00:00-05:00 Michigan Center for Applied and Interdisciplinary Mathematics Lecture / Discussion James Stokes, Flatiron Institute, Simons Foundation
MCAIM / MICDE Joint Sponsored Talk - Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts (November 30, 2021 10:00am) https://events.umich.edu/event/89601 89601-21664516@events.umich.edu Event Begins: Tuesday, November 30, 2021 10:00am
Location:
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

Speaker: James Stokes, Flatiron Institute, Simons Foundation

Title: Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts

Abstract: Stokes will review a family of variational algorithms which have been proposed as candidates to make use of near- to intermediate-term quantum computers, placing particular emphasis on geometric and numeric features that are shared by classical variational stochastic approximation algorithms. Stokes will also discuss some applications of this hybrid quantum-classical approach to scientific and engineering problems beyond its traditional domain of application.

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Lecture / Discussion Tue, 30 Nov 2021 10:06:11 -0500 2021-11-30T10:00:00-05:00 2021-11-30T11:00:00-05:00 Michigan Center for Applied and Interdisciplinary Mathematics Lecture / Discussion James Stokes, Flatiron Institute, Simons Foundation
HET Seminar | Bounds on effective theories of gravity (November 30, 2021 12:00pm) https://events.umich.edu/event/89154 89154-21660700@events.umich.edu Event Begins: Tuesday, November 30, 2021 12:00pm
Location: Randall Laboratory
Organized By: Leinweber Center for Theoretical Physics

*Note Special Time Tuesday 12 noon - 1 PM*

Modifications of Einstein’s theory of gravity can be systematically analyzed using the framework of effective field theory (EFT). In this setup, new physics is captured in a set of higher-dimension operators whose coefficients must be measured experimentally, or matched from a UV completion. It has been known for some time that basic principles, such as unitarity and causality, impose constraints on the allowed values of such coefficients, but a framework to exhaustively explore said constraints has only emerged recently. In this talk I will explain how developments in scattering amplitudes and the conformal bootstrap allowed us to compute sharp numerical bounds on these EFT coefficients. Our results have direct implications for the possibility of testing modifications of General Relativity using gravitational waves and in other astrophysical settings. In addition they also connect with the swampland program. Finally, I will briefly comment on the possibility of obtaining similar results for the Standard Model Effective Theory (SMEFT).

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Lecture / Discussion Wed, 24 Nov 2021 12:46:41 -0500 2021-11-30T12:00:00-05:00 2021-11-30T13:00:00-05:00 Randall Laboratory Leinweber Center for Theoretical Physics Lecture / Discussion Randall Laboratory
CM-AMO Seminar | Examining Topology and Thermodynamics Using Quantum Computers (November 30, 2021 4:00pm) https://events.umich.edu/event/86561 86561-21634898@events.umich.edu Event Begins: Tuesday, November 30, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Quantum hardware has advanced to the point where it is now possible to perform simulations of physical systems and elucidate their topological and thermodynamic properties, which we will discuss in this talk. I will give a brief introduction to quantum computing and why they might be useful tools for solving problems in condensed matter physics and beyond. Following that, I will present a perspective on thermodynamics of quantum systems ideally suited to quantum computers, namely the zeros of the partition function, or Lee-Yang zeros. We developed quantum circuits to measure the Lee-Yang zeros, and used these to reconstruct the thermodynamic partition function of the XXZ model. The zeros qualitatively show the cross-over from an Ising-like regime to an XY-like regime, making this measurement ideally suitable in a NISQ environment. If time permits, I will discuss our demonstration of how topological properties of physical systems can be measured on quantum computers. We leverage the holonomy of the wavefunctions to obtain a noise-free measurement of the Chern number, which we apply to an interacting fermion model.

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Workshop / Seminar Tue, 30 Nov 2021 18:15:58 -0500 2021-11-30T16:00:00-05:00 2021-11-30T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
Department Colloquium | Galaxies Far, Far Away: Mapping the Cosmos with the Dark Energy Survey (December 1, 2021 4:00pm) https://events.umich.edu/event/89471 89471-21663196@events.umich.edu Event Begins: Wednesday, December 1, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Despite tremendous progress in precision cosmology, several core mysteries remain, including the nature of dark energy, dark matter, and gravity. Galaxy surveys, which observe the positions and shapes of galaxies across large areas of the sky, are able to map a significant fraction of our cosmic volume, providing one of the most powerful probes of the Universe. I will describe how we use millions (or billions) of galaxies to measure both galaxy clustering and weak gravitational lensing, and how we learn about the Universe by analyzing these statistics. A significant challenge is that most of the Universe is “dark,” and we must infer from the roughly 5% visible fraction what the remaining 95% is doing. I will focus on the current state of the art, the Year 3 cosmology results from the Dark Energy Survey. I will also preview the exciting future of the field, with the Rubin Observatory and the Dark Energy Spectroscopic Instrument.

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Workshop / Seminar Wed, 01 Dec 2021 18:15:50 -0500 2021-12-01T16:00:00-05:00 2021-12-01T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
Department of Computational Medicine & Bioinformatics Weekly Seminar (December 1, 2021 4:00pm) https://events.umich.edu/event/88514 88514-21654664@events.umich.edu Event Begins: Wednesday, December 1, 2021 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract:

Epigenetic control of gene expression is highly cell-type- and context-specific. Yet, despite its complexity, gene regulatory logic can be broken down into modular components consisting of a transcription factor (TF) activating or repressing the expression of a target gene through its binding to a cis-regulatory region. Recent advances in joint profiling of transcription and chromatin accessibility with single-cell resolution offer unprecedented opportunities to interrogate such regulatory logic. Here, we propose a nonparametric approach, TRIPOD, to detect and characterize three-way relationships between a TF, its target gene, and the accessibility of the TF’s binding site, using single-cell RNA and ATAC multiomic data. We apply TRIPOD to interrogate cell-type-specific regulatory logic in peripheral blood mononuclear cells and contrast our results to detections from enhancer databases, cis-eQTL studies, ChIP-seq experiments, and TF knockdown/knockout studies. We then apply TRIPOD to mouse embryonic brain data during neurogenesis and gliogenesis and identified known and novel putative regulatory relationships, validated by ChIP-seq and PLAC-seq. Finally, we demonstrate TRIPOD on SHARE-seq data of differentiating mouse hair follicle cells and identify lineage-specific regulation supported by histone marks for gene activation and super-enhancer annotations.

Hosted by: Joshua Welch, PhD

Speaker will be in-person and the seminar will be live-streamed via Zoom.

Zoom: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Thu, 21 Oct 2021 14:55:35 -0400 2021-12-01T16:00:00-05:00 2021-12-01T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion Yuchao Jiang (Assistant Professor in the Departments of Biostatistics and Genetics at UNC)
Astronomy Colloquium Series Presents: (December 2, 2021 3:30pm) https://events.umich.edu/event/88720 88720-21656969@events.umich.edu Event Begins: Thursday, December 2, 2021 3:30pm
Location: Off Campus Location
Organized By: Department of Astronomy

Title and abstract coming soon

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Lecture / Discussion Wed, 27 Oct 2021 14:58:45 -0400 2021-12-02T15:30:00-05:00 2021-12-02T17:00:00-05:00 Off Campus Location Department of Astronomy Lecture / Discussion
Life in Graduate School Seminar | Center for Entrepreneurship- Info Session (December 3, 2021 12:00pm) https://events.umich.edu/event/89186 89186-21660986@events.umich.edu Event Begins: Friday, December 3, 2021 12:00pm
Location: West Hall
Organized By: Department of Physics

No matter your passion, interests, previous entrepreneurial experiences or ambitions, the Center for Entrepreneurship (CFE) has specialized opportunities that will expose you to new ways of thinking and support your unique goals. Since its inception in 2008, The Center has developed a rich and diverse set of offerings that cater first to the needs of students. Please come join us in learning about these offerings.

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Workshop / Seminar Fri, 03 Dec 2021 18:15:47 -0500 2021-12-03T12:00:00-05:00 2021-12-03T13:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
Saturday Morning Physics | How Ultrasound May Be Ultra Useful for You! (December 4, 2021 10:30am) https://events.umich.edu/event/85701 85701-21628296@events.umich.edu Event Begins: Saturday, December 4, 2021 10:30am
Location: Off Campus Location
Organized By: Saturday Morning Physics

Ultrasound is a mechanical wave. In medical imaging sophisticated implementations of this physical phenomenon allow us to look inside the human body and obtain useful information. This lecture will highlight recent advances in clinical ultrasound.

Join us on YouTube for Professor Kripfgans talk: https://www.youtube.com/watch?v=WTeLRgcMP9k

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Livestream / Virtual Mon, 29 Nov 2021 11:10:41 -0500 2021-12-04T10:30:00-05:00 2021-12-04T11:30:00-05:00 Off Campus Location Saturday Morning Physics Livestream / Virtual Photo of Professor Kripfgans
HEP-Astro Seminar | Radioactivity and Radio Waves: Project 8 and the Hunt for the Neutrino Mass (December 6, 2021 4:00pm) https://events.umich.edu/event/86659 86659-21635383@events.umich.edu Event Begins: Monday, December 6, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Enrico Fermi's 1934 paper proposing the weak interaction suggested that we should try to measure the neutrino mass via the endpoints of nuclear beta decays. 87 years later, we are still trying to do it; the world's largest electrostatic spectrometer, KATRIN, recently showed that m < 0.8 eV---still far from the scale suggested by neutrino-oscillation mass splittings (0.05-0.008 eV). The Project 8 collaboration is using radio-frequency cyclotron radiation, rather than traditional spectrometers, to detect nuclear beta decay electrons (including, recently, a small-scale tritium endpoint measurement.) In this talk, I'll survey the current science of neutrino mass measurement and show how Project 8 is planning a campaign to study an atomic tritium source with 0.05 eV neutrino mass sensitivity.

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Workshop / Seminar Mon, 06 Dec 2021 18:15:47 -0500 2021-12-06T16:00:00-05:00 2021-12-06T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
CM-AMO Seminar | Optimal Control for Atom Interferometry and High-Precision Measurements (December 7, 2021 4:00pm) https://events.umich.edu/event/89550 89550-21664101@events.umich.edu Event Begins: Tuesday, December 7, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Atomic Fountain Interferometry (AFI) is a disruptive technology for the measurement of gravitational gradients and accelerations with remarkable precision. AFI is based on the manipulation of atom cloud in a free-fall-tower using laser pulses to create a superposition of two momentum space pathways. The interferometric signal contrast is limited by variations in the initial velocity of the atoms in the cloud and variations in the laser amplitude over the cross-section of the cloud. A robust pulse scheme must provide separation, mirroring, and recombination of the atoms to high precision over a realistic range of these variations. In our work we apply optimal control theory to design suitable pulse sequences to improve the efficiency of the AFI device. Our methodology relies on the simulation of the interferometer's full quantum dynamics. We test the efficacy of the proposed pulse schemes using adiabatic passage with frequency-chirped pulses and explore numerical optimal control theory to generate robust pulse schemes and formulate the most general control conditions for the implementation of an interferometer.

Applying optimal control theory for the efficient generation of N-atom non-classical states and their use for atom interferometry and quantum metrology are also discussed. As an example, we design a novel pulse sequence that drives an ensemble of cold trapped atoms into an optimal squeezed state. These states have a fundamental precision scaling proportional to the inverse of the number of atoms, known as the Heisenberg limit.

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Workshop / Seminar Tue, 07 Dec 2021 18:15:52 -0500 2021-12-07T16:00:00-05:00 2021-12-07T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
Special Interdisciplinary QC/CM Seminar | Emergent Phenomena and Broken Symmetries: One-dimensional Objects and their Dot/Cross Products (December 8, 2021 12:00pm) https://events.umich.edu/event/89490 89490-21663320@events.umich.edu Event Begins: Wednesday, December 8, 2021 12:00pm
Location: West Hall
Organized By: Department of Physics

Emergent physical phenomena and broken symmetries can be linked through one-dimensional objects and their dot or cross products. Eight kinds of one-dimensional (1D) objects (four; vector-like, the other four; director-like) and their dot/cross products are defined in terms of symmetry. The dot or products form certain mathematical groups. Those 1D objects are associated with characteristic physical phenomena, and when a 3D system has identical or lower (but not higher) symmetries than an 1D object with particular phenomena, the 3D system can exhibit the phenomena. Using this straightforward concept, we can understand and also predict numerous new emergent phenomena in known materials or new complex materials for desired phenomena.

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Workshop / Seminar Wed, 08 Dec 2021 18:15:54 -0500 2021-12-08T12:00:00-05:00 2021-12-08T13:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
MIPSE Seminar | Dynamics of Low Temperature Magnetized Plasmas: Self-Organization and Anomalous Electron Transport (December 8, 2021 3:30pm) https://events.umich.edu/event/86298 86298-21632606@events.umich.edu Event Begins: Wednesday, December 8, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Low-temperature magnetized plasmas are found in many systems, including plasma processing, space weather, and spacecraft propulsion. Two phenomena that are poorly understood in cross-electric and magnetic field plasma sources, such as magnetrons and Hall effect thrusters, are: (i) self-organized structures and (ii) anomalous electron transport across the magnetic field lines. In this talk, I will present the development of physics-based modeling, including fluid moment models and high-fidelity kinetic models, to address these processes. The fluid moment model coupled with improved boundary condition treatments is applied to low-temperature magnetized plasmas. The particle-based kinetic models are used to investigate multidimensional plasma turbulence initiated by a combination of kinetic instabilities in cross-field configurations. I will also introduce data-driven modeling using optimization and state estimation techniques applied to dynamical plasma systems.

About the Speaker:
Ken Hara is an Assistant Professor of Aeronautics and Astronautics at Stanford University. He received his Ph.D. in Aerospace Engineering and Graduate Certificate in Plasma Science and Engineering from the University of Michigan in 2015, and B.S. and M.S. in Aeronautics and Astronautics from the University of Tokyo in 2008 and 2010, respectively. He was a Visiting Research Physicist at Princeton Plasma Physics Laboratory as a Japan Society for the Promotion of Science Postdoctoral Fellow. He is a recipient of several awards, including the Air Force Young Investigator Program Award, the Department of Energy Early Career Award, and the Office of Naval Research Young Investigator Program Award.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:49:26 -0400 2021-12-08T15:30:00-05:00 2021-12-08T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Ken Hara
MCAIM / MICDE Joint Sponsored Talk - Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts (December 8, 2021 4:00pm) https://events.umich.edu/event/89601 89601-21664514@events.umich.edu Event Begins: Wednesday, December 8, 2021 4:00pm
Location: East Hall
Organized By: Michigan Center for Applied and Interdisciplinary Mathematics

Speaker: James Stokes, Flatiron Institute, Simons Foundation

Title: Geometry and Numerics of Variational Quantum Algorithms and Classical Counterparts

Abstract: Stokes will review a family of variational algorithms which have been proposed as candidates to make use of near- to intermediate-term quantum computers, placing particular emphasis on geometric and numeric features that are shared by classical variational stochastic approximation algorithms. Stokes will also discuss some applications of this hybrid quantum-classical approach to scientific and engineering problems beyond its traditional domain of application.

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Lecture / Discussion Tue, 30 Nov 2021 10:06:11 -0500 2021-12-08T16:00:00-05:00 2021-12-08T17:00:00-05:00 East Hall Michigan Center for Applied and Interdisciplinary Mathematics Lecture / Discussion James Stokes, Flatiron Institute, Simons Foundation
Astronomy Colloquium Series Presents: (December 9, 2021 3:30pm) https://events.umich.edu/event/88721 88721-21656970@events.umich.edu Event Begins: Thursday, December 9, 2021 3:30pm
Location: Off Campus Location
Organized By: Department of Astronomy

Title and abstract coming soon

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Lecture / Discussion Wed, 27 Oct 2021 15:00:35 -0400 2021-12-09T15:30:00-05:00 2021-12-09T17:00:00-05:00 Off Campus Location Department of Astronomy Lecture / Discussion
Interdisciplinary QC/CM Seminar | Outrunning Decoherence: Fast State Preparation for Accurate, Near-Ish-Term Variational Quantum Computing (December 9, 2021 4:00pm) https://events.umich.edu/event/86569 86569-21634906@events.umich.edu Event Begins: Thursday, December 9, 2021 4:00pm
Location: West Hall
Organized By: Department of Physics

Ab initio molecular simulation provides a sub-atomic understanding of chemical reactions and properties. However, due to the exponential scaling of many-body simulations, one can only obtain approximate solutions to the electronic Schrodinger equation. Although, in principle one can increase the sophistication of an approximation arbitrarily until a desired accuracy is reached, more sophisticated calculations rapidly become intractable for even the largest supercomputers. Quantum computers provide a promising route to bypass these limitations in molecular simulation. However, current and near term quantum devices suffer from environmental noise and gate errors, thus limiting the calculations able to be achieved. In this talk, I will discuss basic ideas concerning the simulation of molecules on quantum devices, and describe two different algorithmic directions our collaborative team has recently devised for trying to extract the most computational work out of noisy devices.

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Workshop / Seminar Thu, 09 Dec 2021 18:15:44 -0500 2021-12-09T16:00:00-05:00 2021-12-09T17:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
Complex Systems Presents the Annual Nobel Symposium (December 10, 2021 10:00am) https://events.umich.edu/event/89502 89502-21664099@events.umich.edu Event Begins: Friday, December 10, 2021 10:00am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

CLICK TO SEE RECORDINGS OF THE TALKS: https://lsa.umich.edu/cscs/news-events/all-events/event-recordings.html

Registration not required. Free and open to the public. This will be a virtual symposium. This popular annual event features UM faculty experts in each of the six prize fields. Each will present for approximately 25 minutes and then will take some questions. There is a scheduled lunch break. Come to one talk, come to them all.

SCHEDULE
10:00 AM Opening remarks, Marisa Eisenberg, Interim Director of Complex Systems
10:05 AM Physics, Mark Newman, LSA Complex Systems & Physics AND Richard Rood, Engineering & SEAS
10:55 AM Chemistry, Corey Stephenson, LSA Chemistry
11:30 AM Physiology or Medicine, Shawn Xu, Michigan Medicine Molecular and Integrative Physiology & Life Sciences Institute AND Rui Xiao, University of Florida, Center for Smell and Taste (special guest and Michigan Alumni)

12:05 PM Lunch break

1:00 PM Economics: Tanya Rosenblat, School of Information and LSA Economics
1:35 PM Literature: Gaurav Desai, LSA English Language and Literature
*This talk is co-sponsored by the African Studies Center (ii.umich.edu/asc)*
2:10 PM Peace: Lynette Clemetson, Wallace House (Knight-Wallace Fellowships) AND Ron Suny, LSA History & Political Science
3:00 PM Closing remarks

For information on prize winners, please click the Nobel Prize winners link below. Other information on the Nobel Prizes can be found on the website nobelprize.org

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Conference / Symposium Wed, 22 Dec 2021 21:25:28 -0500 2021-12-10T10:00:00-05:00 2021-12-10T15:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Conference / Symposium Symposium Poster
HET Seminar | Kerr Geodesics and Self-consistent match between Inspiral and Transition-to-merger (December 10, 2021 3:00pm) https://events.umich.edu/event/89655 89655-21664737@events.umich.edu Event Begins: Friday, December 10, 2021 3:00pm
Location: Off Campus Location
Organized By: Leinweber Center for Theoretical Physics

The two-body motion in General Relativity can be solved perturbatively in the small mass ratio expansion. Kerr geodesics describe the leading order motion.
After a short summary of the classification of polar and radial Kerr geodesic motion, I will consider the inspiral motion of a point particle around the Kerr black hole
subjected to the self-force. I will describe its quasi-circular inspiral motion in the radiation timescale expansion. I will describe in parallel the transition-to-merger motion around the last stable
circular orbit and prove that it is controlled by the Painlevé transcendental equation of the first kind. I will then prove that one can consistently match the two motions using
the method of asymptotically matched expansions.

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Lecture / Discussion Wed, 01 Dec 2021 09:22:06 -0500 2021-12-10T15:00:00-05:00 2021-12-10T16:00:00-05:00 Off Campus Location Leinweber Center for Theoretical Physics Lecture / Discussion
CM-AMO Seminar | Quantum Computing With Semiconductor Spins (December 13, 2021 11:00am) https://events.umich.edu/event/89611 89611-21664557@events.umich.edu Event Begins: Monday, December 13, 2021 11:00am
Location: West Hall
Organized By: Department of Physics

Recent years have witnessed enormous progress toward the development of quantum computers---novel devices that exploit quantum mechanics to perform tasks far beyond the reach of the world’s best supercomputers. Qubits based on semiconductor spins are particularly promising because of their long coherence times and prospects for scaling up to large processors by leveraging the existing semiconductor electronics infrastructure. However, many fundamental challenges related to decoherence, controllability, and device architecture remain. I will describe our efforts to address these challenges on multiple fronts using smart control schemes, bath-state engineering with Floquet physics, and entanglement generation between remote spins.

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Workshop / Seminar Mon, 13 Dec 2021 18:15:39 -0500 2021-12-13T11:00:00-05:00 2021-12-13T12:00:00-05:00 West Hall Department of Physics Workshop / Seminar West Hall
RNA Faculty Candidate Seminar (December 13, 2021 4:00pm) https://events.umich.edu/event/89524 89524-21663803@events.umich.edu Event Begins: Monday, December 13, 2021 4:00pm
Location: Taubman Biomedical Science Research Building
Organized By: Center for RNA Biomedicine

In-person/Hybrid seminar co-hosted by the Center for RNA Biomedicine and the Department of Molecular, Cellular, and Developmental Biology

Talk title: “Resolving the localisation and dynamics of mRNA and protein synthesis within neurons”

Keywords: mRNA dynamics, local protein synthesis, neurons, neuronal cell biology, synaptic plasticity, in vivo imaging

If you are having trouble registering, please contact Martina Jerant at mjerant@umich.edu

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Lecture / Discussion Tue, 30 Nov 2021 13:12:23 -0500 2021-12-13T16:00:00-05:00 2021-12-13T17:00:00-05:00 Taubman Biomedical Science Research Building Center for RNA Biomedicine Lecture / Discussion Paul Donlin-Asp, Ph.D.,
CGIS Virtual First Step Sessions (January 10, 2022 12:00pm) https://events.umich.edu/event/74423 74423-21668872@events.umich.edu Event Begins: Monday, January 10, 2022 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

Every Wednesday beginning June 1st through August 3rd @ noon
First Step Sessions will be taking place during the spring & summer! Beginning Wednesday, June 1st through Wednesday, August 3rd, CGIS will be holding weekly First Step Sessions. 

First Step sessions are a great opportunity to learn more about the application process prior to meeting with an advisor. You can learn about all of our programs around the world, scholarships and other financial aid resources, the CGIS application process, and more! 

Attending a First Step session will no longer be a required component of the CGIS application process.

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Livestream / Virtual Wed, 24 Aug 2022 12:33:20 -0400 2022-01-10T12:00:00-05:00 2022-01-10T12:30:00-05:00 Off Campus Location Center for Global and Intercultural Study Livestream / Virtual PHOTO
HEP-Astro Seminar | Probing Cosmic Structure Growth with Full-Scale Cross-Survey Modeling (January 10, 2022 4:00pm) https://events.umich.edu/event/90690 90690-21672377@events.umich.edu Event Begins: Monday, January 10, 2022 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link: https://umich.zoom.us/j/91409362110?pwd=UDlja2FuYlZWVFNEMWFrOTlkWFNEZz09

The canonical picture of cosmology, the Lambda Cold Dark Matter (LCDM) model, has been remarkably successful in explaining a large variety of different observations. However, in recent years, apparent tensions in this standard model have started to appear and spark interest in alternative cosmological models. Cosmic structure growth as probed by large-scale structure (LSS) galaxy surveys is one of the most sensitive probes of dark energy and physics beyond LCDM. First, I will summarize recent results from LSS surveys analyzing weak gravitational lensing, focusing on the possibility of a cosmological growth-of-structure tension. I will then present ongoing efforts to maximize the information content we can extract from LSS surveys through full-scale cross-survey modeling. First, I will discuss how the "lensing is low" problem can illuminate our understanding of cosmic structure growth, galaxy formation, and small-scale baryonic physics. Afterward, I will present a full-scale cosmology study of redshift-space galaxy clustering. I show that such an analysis yields some of the most stringent constraints on the cosmic growth rate of the Universe to date. Finally, I will give an outlook on what to expect from similar studies with the upcoming Dark Energy Spectroscopic Instrument (DESI).

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Workshop / Seminar Mon, 10 Jan 2022 18:15:54 -0500 2022-01-10T16:00:00-05:00 2022-01-10T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
CGIS Virtual First Step Sessions (January 11, 2022 12:00pm) https://events.umich.edu/event/74423 74423-21668887@events.umich.edu Event Begins: Tuesday, January 11, 2022 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

Every Wednesday beginning June 1st through August 3rd @ noon
First Step Sessions will be taking place during the spring & summer! Beginning Wednesday, June 1st through Wednesday, August 3rd, CGIS will be holding weekly First Step Sessions. 

First Step sessions are a great opportunity to learn more about the application process prior to meeting with an advisor. You can learn about all of our programs around the world, scholarships and other financial aid resources, the CGIS application process, and more! 

Attending a First Step session will no longer be a required component of the CGIS application process.

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Livestream / Virtual Wed, 24 Aug 2022 12:33:20 -0400 2022-01-11T12:00:00-05:00 2022-01-11T12:30:00-05:00 Off Campus Location Center for Global and Intercultural Study Livestream / Virtual PHOTO
CGIS Virtual First Step Sessions (January 12, 2022 12:00pm) https://events.umich.edu/event/74423 74423-21674674@events.umich.edu Event Begins: Wednesday, January 12, 2022 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

Every Wednesday beginning June 1st through August 3rd @ noon
First Step Sessions will be taking place during the spring & summer! Beginning Wednesday, June 1st through Wednesday, August 3rd, CGIS will be holding weekly First Step Sessions. 

First Step sessions are a great opportunity to learn more about the application process prior to meeting with an advisor. You can learn about all of our programs around the world, scholarships and other financial aid resources, the CGIS application process, and more! 

Attending a First Step session will no longer be a required component of the CGIS application process.

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Livestream / Virtual Wed, 24 Aug 2022 12:33:20 -0400 2022-01-12T12:00:00-05:00 2022-01-12T12:30:00-05:00 Off Campus Location Center for Global and Intercultural Study Livestream / Virtual PHOTO
Department Colloquium | Discovery and Design of Emergent Behavior in Soft Materials (January 12, 2022 4:00pm) https://events.umich.edu/event/90691 90691-21672378@events.umich.edu Event Begins: Wednesday, January 12, 2022 4:00pm
Location: Off Campus Location
Organized By: Department of Physics

Zoom link: https://umich.zoom.us/j/94692610056

Nature organizes itself with often startling complexity at every length scale accessible to human inquiry, resulting in a range of organic and inorganic materials with emergent and varied structural and dynamical properties. An outstanding current goal of materials science is to harness the often subtle self-organization displayed by Nature in order to design materials with tailor-made functionalities in the laboratory. This talk will focus on efforts, in support of that goal, to understand how local structure and local rules give rise to global behavior in soft materials on the nano- and micro-scales. I will first discuss amorphous and jammed colloidal systems, where local structure arises initially due to sample preparation, and subsequently influences rearrangement dynamics and material memory effects under oscillatory shear [1]. I will then discuss systems of colloidal particles with very short-range interactions, where local structure emerges entirely due to entropic considerations. In these systems, local structure can (i) determine whether materials crystallize or fail to do so entirely [2], (ii) tune relaxation behavior in the glass-forming regime [3], and (iii) give rise to crystallization pathways of varying complexity [4,5]. Finally, I will briefly discuss recent work characterizing local microstructure in the biological context of the human brain, and potential applications related to brain development, aging, and neurodegenerative disease [6]. This work collectively demonstrates the enormous impact of simple local rules on complex global behavior in material and biological systems, and points toward exciting future directions related to the design of those behaviors.

[1] E.G. Teich, K.L. Galloway, P.E. Arratia, and D.S. Bassett, Science Advances 7, eabe3392 (2021).
[2] E.G. Teich, G. van Anders, and S.C. Glotzer, Nature Communications 10, 64 (2019).
[3] E.G. Teich, G. van Anders, and S.C. Glotzer, Soft Matter 17, 600 (2021).
[4] E.G. Teich, G. van Anders, D. Klotsa, J. Dshemuchadse, and S.C. Glotzer, Proc. Natl. Acad. Sci. USA 113, E669 (2016).
[5] S. Lee, E.G. Teich, M. Engel, and S.C. Glotzer, Proc. Natl. Acad. Sci. USA 116, 14843 (2019).
[6] E.G. Teich, M. Cieslak, B. Giesbrecht, J.M. Vettel, S.T. Grafton, T.D. Satterthwaite, and D.S. Bassett, New Journal of Physics 23, 073047 (2021).

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Workshop / Seminar Wed, 12 Jan 2022 18:15:59 -0500 2022-01-12T16:00:00-05:00 2022-01-12T17:00:00-05:00 Off Campus Location Department of Physics Workshop / Seminar
CGIS Virtual First Step Sessions (January 13, 2022 12:00pm) https://events.umich.edu/event/74423 74423-21674673@events.umich.edu Event Begins: Thursday, January 13, 2022 12:00pm
Location: Off Campus Location
Organized By: Center for Global and Intercultural Study

Every Wednesday beginning June 1st through August 3rd @ noon
First Step Sessions will be taking place during the spring & summer! Beginning Wednesday, June 1st through Wednesday, August 3rd, CGIS will be holding weekly First Step Sessions. 

First Step sessions are a great opportunity to learn more about the application process prior to meeting with an advisor. You can learn about all of our programs around the world, scholarships and other financial aid resources, the CGIS application process, and more! 

Attending a First Step session will no longer be a required component of the CGIS application process.

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Livestream / Virtual Wed, 24 Aug 2022 12:33:20 -0400 2022-01-13T12:00:00-05:00 2022-01-13T12:30:00-05:00 Off Campus Location Center for Global and Intercultural Study Livestream / Virtual PHOTO