Happening @ Michigan https://events.umich.edu/list/rss RSS Feed for Happening @ Michigan Events at the University of Michigan. Causal Inference in Education Research Seminar (CIERS): Attrition from administrative data: Problems and solutions with an application to higher education (September 18, 2019 8:30am) https://events.umich.edu/event/67158 67158-16805233@events.umich.edu Event Begins: Wednesday, September 18, 2019 8:30am
Location: Weill Hall (Ford School)
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 13 Sep 2019 13:58:16 -0400 2019-09-18T08:30:00-04:00 2019-09-18T10:00:00-04:00 Weill Hall (Ford School) Department of Economics Workshop / Seminar economics
MIPSE Seminar | Simulation-Guided Design of a MegaJoule Dense Plasma Focus (September 18, 2019 3:30pm) https://events.umich.edu/event/65588 65588-16619786@events.umich.edu Event Begins: Wednesday, September 18, 2019 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
A dense plasma focus (DPF) is a relatively compact coaxial plasma gun which completes its discharge as a Z-pinch. These devices have been designed to operate at a variety of scales in to produce short (<100 ns) pulses of ions, X-rays, or neutrons. LLNL has recently constructed and brought into operation a new device, the MJOLNIR (MegaJouLe Neutron Imaging Radiography) DPF which is designed for radiography and high yield operations. This device has been commissioned over the last year and has achieved neutron yields up to 9x10^11 neutrons/pulse at 2.2 MA pinch current while operating at up to 1 MJ of stored energy. MJOLNIR is equipped with a wide range of diagnostics, including activation foils, neutron time of flight detectors, a fast framing camera, optical light gates, and a time-gated neutron and x-ray imager. LLNL also runs unique particle-in-cell (PIC) simulations of DPF in the Chicago code, and has been able to gain significant insight into the physical factors that influence neutron yield. To that end, MJOLNIR is one of the first DPFs whose design and continual upgrades are heavily influenced by predictive modeling. In this presentation, we will describe insights from modeling, device operation, and recent results. Preliminary x-ray and neutron images will also be presented.

About the Speaker:
Dr. Andrea Schmidt is group leader of the Plasma Engineering Group and Associate Program Lead for Pulsed Power Fusion Plasmas at Lawrence Livermore National Laboratory (LLNL). She received her Ph.D. in Physics from MIT and her BS in Physics from the U. of California/Berkeley. She joined LLNL as a postdoctoral researcher in 2011 and joined the staff in 2013. As a postdoc, Schmidt was involved in electrical grid research, and modeling the dense plasma focus (DPF) device. She performed the first kinetic modeling of a DPF, demonstrating that a particle approach was needed to capture beam formation and neutron yield. She is now leading several projects in DPF research including the development of a large MJ-class DPF experiment built for flash neutron radiography. Schmidt also led modeling and experimental efforts for magnetron sputtering and was part of a team investigating a shear-flow-stabilized z-pinch configuration for controlled fusion.

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Lecture / Discussion Thu, 22 Aug 2019 11:04:06 -0400 2019-09-18T15:30:00-04:00 2019-09-18T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Andrea Schmidt
Labor Economics (September 19, 2019 11:30am) https://events.umich.edu/event/66525 66525-16744970@events.umich.edu Event Begins: Thursday, September 19, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 06 Sep 2019 14:13:59 -0400 2019-09-19T11:30:00-04:00 2019-09-19T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Applied Microeconomics/IO Seminar: Quantifying the Benefits to Consumers of Subscription-based Streaming Video Service (September 20, 2019 10:00am) https://events.umich.edu/event/67157 67157-16805232@events.umich.edu Event Begins: Friday, September 20, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

This paper builds a structural model of the demand for television subscription services in the United States in order to quantify the benefits from the new product---streaming video services. A new dataset on the television services prices and characteristics is used to estimate the model. The paper then calculates the compensating variation for the counterfactual simulation which removes streaming services from the consumer's choice set.

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Workshop / Seminar Fri, 20 Sep 2019 08:20:02 -0400 2019-09-20T10:00:00-04:00 2019-09-20T11:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
MCDB Seminar: Developmental Origins of Neural Circuits in Drosophila (September 20, 2019 12:00pm) https://events.umich.edu/event/64082 64082-16115266@events.umich.edu Event Begins: Friday, September 20, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Josie Clowney

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Workshop / Seminar Tue, 27 Aug 2019 17:12:34 -0400 2019-09-20T12:00:00-04:00 2019-09-20T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Confocal image of multicolor stained intact Drosophila larva
2019 FinTech Conference (September 20, 2019 1:00pm) https://events.umich.edu/event/66259 66259-16721680@events.umich.edu Event Begins: Friday, September 20, 2019 1:00pm
Location: Ross School of Business
Organized By: Michigan FinTech

Connecting the brightest students, luminaries, and industry leaders
in the field of financial technology

The 2019 FinTech Conference will feature a FinTech career panel; keynote address from David McClelland, CEO of Ford Credit; technical presentation from U of M alum Elaine Wah; and career fair.

Connect with representatives from JP Morgan, IEX, Clinc, among others eager to share their experiences and recruit U-M talent.

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Conference / Symposium Tue, 03 Sep 2019 19:43:58 -0400 2019-09-20T13:00:00-04:00 2019-09-20T17:00:00-04:00 Ross School of Business Michigan FinTech Conference / Symposium 2019 FinTech Conference
Economics at Work (September 20, 2019 1:00pm) https://events.umich.edu/event/65823 65823-16660086@events.umich.edu Event Begins: Friday, September 20, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Vikram is the Senior Director of Marketing at the Clorox Company. In this role, he leads an organization focused on brand building, insights & innovation across a $2B portfolio. Vikram started at the Clorox Company as the Director of Shopper & Retail Insight, leading the development of Retail Insight & Analytic capability.

Vikram has extensive experience in marketing and market research. In his 10 years at Procter & Gamble, he managed corporate, brand and retail parts of a Consumer Packaged Goods firm, including global brands and a top retail team. Vikram is a proven innovator: He has led identification and successful launches of Bounty Basic, Target’s Baby Registry, Virtual Beauty Advisory Capability, Sam’s Member Tailgate Awards, Kroger Home Care (Redesign) and Clorox Scentiva.

In addition, while out of the office, Vikram is an avid golfer and Michigan sports fanatic.



Economics@Work (Econ 208) is an invited alumni speaker series that allows students to discover the wide array of career paths available to economics majors and the role economics could play in their careers. In Economics@Work, undergraduates are offered a regular opportunity to network and interact with alumni from the Department of Economics. You’ll discover that economists are engaged in a wide array of professions from investment banking, finance and government, to legislation, advocacy, and online sales and marketing, among many others. This one-credit (credit/no credit) course meets eight (possibly nine) times during the semester. Sessions include a presentation and time for questions. They are followed by a reception in the Foster Library, allowing time to network with speakers.

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Tue, 17 Sep 2019 12:45:04 -0400 2019-09-20T13:00:00-04:00 2019-09-20T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory (September 20, 2019 2:30pm) https://events.umich.edu/event/65828 65828-16660091@events.umich.edu Event Begins: Friday, September 20, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 27 Aug 2019 08:22:45 -0400 2019-09-20T14:30:00-04:00 2019-09-20T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Persistent Overconfidence and Biased Memory: Evidence from Managers (September 23, 2019 11:45am) https://events.umich.edu/event/65829 65829-16660093@events.umich.edu Event Begins: Monday, September 23, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract:

A long-standing puzzle is whether and how overconfidence can persist in field settings characterized by repeated feedback. This paper studies managers who participate repeatedly in a high-powered tournament incentive system, learning relative performance each time. Using both reduced form and structural methods we find that: (i) managers make overconfident predictions about future performance; (ii) managers have overly-positive memories of past performance; (iii) the two phenomenon are linked at an individual level in a way consistent with models of motivated beliefs.

with David Huffman and Julia Shvet

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Workshop / Seminar Tue, 27 Aug 2019 08:29:16 -0400 2019-09-23T11:45:00-04:00 2019-09-23T12:45:00-04:00 North Quad Department of Economics Workshop / Seminar economics
Public Finance: Tax Reform and the Valuation of Super-star Firms (September 23, 2019 4:00pm) https://events.umich.edu/event/66600 66600-16767939@events.umich.edu Event Begins: Monday, September 23, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

Upon a reduction in corporate tax rates, theory tells us that the absolute increase in the value of a firm's equity is increasing in its productivity, while the excess return is related ambiguously to productivity. Using data on the U.S. stock market, I show that the excess returns due news on the latest U.S. tax reform are strongly related to traditional measures of firm profitability and market power. Compared to a firm in perfect competition, my model predicts that a monopolist would see its excess return increased by between 5 and 105 percentage points more upon news of the tax cut. I use this fact to construct a new measure of firm profitability based on its stock market reaction to the Tax Cuts and Jobs Act. My results show that profitability across U.S. firms is distributed with a long right tail, confirming results from a growing literature documenting an increase in mark-ups and a concentration of market power in the U.S. economy.

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Workshop / Seminar Mon, 23 Sep 2019 09:54:19 -0400 2019-09-23T16:00:00-04:00 2019-09-23T17:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Kevin Taaffe, PhD (September 23, 2019 4:30pm) https://events.umich.edu/event/66810 66810-16779022@events.umich.edu Event Begins: Monday, September 23, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Hospitals have introduced information technology to improve the ability of staff to react in a timely fashion, but with mixed success. Hospitals have also continued to build new operating rooms, but advances in patient care and safety are not always evident. In this seminar, we address these two areas of concern regarding day-of-surgery patient flow and safety. Part 1: We describe the development and testing of a mobile application to explore if the use of technology could reduce barriers to communication and coordination on the day of surgery. While staff members in a hospital’s perioperative services department perform their work individually, their choices of upcoming tasks depend on data they can either observe or gather verbally in order to maintain patient flow. Without constant communication with members of other departments, staff may inadvertently select lower priority tasks, which is counter-productive to perioperative services as a whole. The developed mobile application, Periop-MLS, provided each department and its members greater visibility of the workflow. To carry out user testing, the researchers integrated a day-of-surgery discrete event simulation model to communicate with the mobile app to provide realistic scenarios. Through trial-runs of Periop-MLS with staff members, the POS department was able to make proactive coordination and communication decisions. Part 2: It is important to design an operating room layout that can not only improve staff and patient safety but also increase efficiency. In this research, we identify those design factors that influence safety and efficiency through reduced clutter, congestion, and staff walking during surgery. A sample of video-taped surgeries from a large academic hospital were studied to understand the movement of surgical staff during surgery. All activities were coded based on location, activity type, and purpose, and then simulation methodology was used to study the different activity types and movement patterns inside the room. Based on OR size, OR shape, operating table orientation, workstation locations, number of staff, number of doors, and surgery type, we provided critical insight to OR managers and researchers as they determine recommendations for OR design elements and inform the design of future operating rooms.

Kevin M. Taaffe, Ph.D., the Harriet and Jerry Dempsey Professor in Industrial Engineering at Clemson University, has 25 years of industry and academic experience. After receiving B.S. and M.S. degrees in Industrial Engineering from the University of Illinois, Dr. Taaffe worked in the transportation logistics industry (American Airlines, Sabre) for eight years, before returning to academia to obtain his Ph.D. from the University of Florida. Dr. Taaffe’s research interests include the application of simulation and optimization in healthcare, production, and transportation logistics. In particular, Dr. Taaffe focuses on healthcare logistics problems that range from patient flow to operating room management to clinical space capacity management. Dr. Taaffe has worked with clinicians, administrators, managers, and support staff to identify and solve problems related to the patient and staff experience on the day of surgery. Dr. Taaffe began his career working as a transportation planning consultant, and there is a logical research thrust that has resulted from this experience. He has always enjoyed working on industry-sponsored projects that bridge the gap between theoretical research and application. This academic/industry collaboration is a theme of Dr. Taaffe’s interest, as can be seen by his named professorship. Harriet and Jerry Dempsey provided this professorship in an effort to strengthen the research ties between Clemson University and Prisma Health – Upstate.  In addition to his academic and research interests, Dr. Taaffe plays an important role in the Institute of Industrial and Systems Engineers (IISE) where he serves as the Senior VP of North American Operations. In this role, he is helping students and professionals get the most out of their professional organization.

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Lecture / Discussion Tue, 10 Sep 2019 15:17:53 -0400 2019-09-23T16:30:00-04:00 2019-09-23T18:00:00-04:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Kevin Taaffe, PhD
Complex Systems Seminar | Statistical Mechanics of Microbiomes (September 24, 2019 11:30am) https://events.umich.edu/event/63981 63981-16051364@events.umich.edu Event Begins: Tuesday, September 24, 2019 11:30am
Location: Weiser Hall
Organized By: The Center for the Study of Complex Systems

Abstract: Next-generation sequencing, high-throughput metabolomics and other measurement technologies have opened vast new horizons for collecting data on the structure and function of microbial communities. But it remains unclear how to leverage this data for effective intervention in medical and agricultural applications. We do not know which quantities can be reliably predicted, which are hopelessly contingent, and what the predictors are for the former. In this talk, I will draw on conceptual tools from Statistical Physics, which were designed to answer precisely these sorts of questions. In particular, I will argue that the key features of community structure are encoded in a susceptibility matrix, which contain the response of species population sizes to small changes in growth rates. I will show how to estimate this matrix in different scenarios from existing data sets, and then explain how it can be used to cluster species into functionally redundant groups for enhanced predictability of community composition.

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Workshop / Seminar Wed, 18 Sep 2019 15:55:41 -0400 2019-09-24T11:30:00-04:00 2019-09-24T13:00:00-04:00 Weiser Hall The Center for the Study of Complex Systems Workshop / Seminar Robert Marsland Photo
Rowena Matthews Lectureship in Biological Chemistry (September 24, 2019 12:00pm) https://events.umich.edu/event/65273 65273-16563500@events.umich.edu Event Begins: Tuesday, September 24, 2019 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Wilfred van der Donk will present the 2nd annual Rowena Matthews Lectureship in Biological Chemistry on Tuesday September 24th, 2019. The title of this talk is "Natural Product Biosynthesis by Post Translational Modification." The lecture will be held in Medical Science Unit II from 12:00pm to 1:00pm.

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Lecture / Discussion Wed, 18 Sep 2019 06:17:48 -0400 2019-09-24T12:00:00-04:00 2019-09-24T13:00:00-04:00 Medical Science Unit II Biological Chemistry Lecture / Discussion Wilfred van der Donk, Ph.D.
ChE Seminar Series: Brian Aguado (September 24, 2019 1:30pm) https://events.umich.edu/event/65446 65446-16597590@events.umich.edu Event Begins: Tuesday, September 24, 2019 1:30pm
Location:
Organized By: Chemical Engineering

>This Seminar will be held in the North Campus Research Complex, Building 32, Auditorium

"Precision biomaterial platforms to probe valvular fibroblast activation"

ABSTRACT

Aortic valve stenosis (AVS) is a progressive disease characterized by aberrant stiffening of the aortic valve, leading to inadequate blood flow from the left ventricle and eventual heart failure. AVS is currently treated exclusively with valve replacement surgeries, which may be avoided if effective small molecule therapeutics could be identified to slow or reverse AVS progression. During AVS progression, a large fraction of valvular interstitial cells (VICs) differentiate into pathogenically activated myofibroblasts, which contribute to excessive matrix deposition and eventual valve leaflet stiffening. Effective small molecule therapeutics intended to reverse myofibroblast activation remain elusive, owing to the inherent heterogeneity of the cellular microenvironment from patient to patient. For example, male patients show increased calcification and female patients show increased tissue fibrosis in the aortic valve microenvironment, leading to differential drug responses. Considering these clinical observations, we seek to engineer precision biomaterial microenvironments to recapitulate sex- and patient-specific AVS progression in vitro and identify molecular mechanisms that mediate reversal of myofibroblast activation. Precision biomaterials are defined here as engineered environments that enable the evaluation of how sex- and/or patient-specific variables may influence disease progression. As a strategy to evaluate molecular mechanisms guiding AVS progression, we utilize poly(ethylene glycol) (PEG) hydrogels as precision in vitro platforms to probe various biochemical and mechanical cues that activate male and female VICs to a myofibroblast state, as well as cues that reverse activation (Fig. 1A). My talk will focus on two vignettes where PEG hydrogels were used to evaluate how male and female VICs activate to and reverse from a myofibroblast state in response to different cues, including (1) serum factors from AVS patients before and after a valve replacement procedure and (2) small molecule inhibitors of myofibroblast activation. Collectively, our work demonstrates how engineered hydrogel matrices enable an increased understanding of the molecular mechanisms guiding myofibroblast activation and reversal, which may provide a critical bridge toward sex- and patient-specific small molecule AVS therapies.

SHORT BIO

Dr. Brian Aguado is currently an NIH K99 and Burroughs Wellcome Fund postdoctoral fellow at the University of Colorado. His current research is focused on developing precision biomaterials for applications in personalized medicine. Dr. Aguado completed his MS and PhD in biomedical engineering from Northwestern University and his BS degree in biomechanical engineering from Stanford University. He also obtained his certificate in Management for Scientists and Engineers from the Kellogg School of Management at Northwestern. Dr. Aguado is also a dedicated science communicator outside of the lab and seeks to engage underrepresented populations in the sciences. He is the former president of the Postdoctoral Association of Colorado, organized seminars featuring underrepresented thought leaders in STEM for CU Café, and served on the executive board for Project Bridge Colorado. Most recently, he co-founded LatinXinBME, a new social media initiative dedicated to building a diverse and inclusive community of Latinx biomedical engineers and scientists to support each other personally and professionally through their careers.

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Lecture / Discussion Wed, 21 Aug 2019 16:13:30 -0400 2019-09-24T13:30:00-04:00 2019-09-24T14:30:00-04:00 Chemical Engineering Lecture / Discussion
Mechanical Engineering Seminar Series (September 24, 2019 4:00pm) https://events.umich.edu/event/67552 67552-16892242@events.umich.edu Event Begins: Tuesday, September 24, 2019 4:00pm
Location: GG Brown Laboratory
Organized By: Mechanical Engineering

Speaker: Amy Marconnet - Associate Professor at Purdue University

Abstract
Nanostructuring material s allows independent control of multiple material s properties. High conductivity material s such as carbon nanotube forests are useful as thermal interface materials (TIMs) for dissipating power in electronic devices, while low conductivity material s like nanoporous silicon for thermal barrier coatings and enhanced thermoelectric performance. Beyond thermal transport, storage of thermal energy is critical for effective heat removal for applications involving
highly-transient heat fluxes, and during material processing. Often to achieve the desired functionality, multiples material s are combined together to form heterogeneous composites. For example, in lithium-ion batteries, the particulate active material s (with micro- and nano-scale features) are sandwiched between metal electrodes and polymer-based separators with microscale thicknesses to form macroscale battery cells. This seminar will discuss methods to understand and
control thermal transport and development of accurate and reliable experimental and analytical techniques for thermal characterization across multiple length scales. Further, I will highlight the integration of material synthesis with thermal property measurements and physics-based analysis to provide new avenues for improved material s and device performance.

Bio
Amy Marconnet i s an Associate Professor of Mechanical Engineering at Purdue University. She received a B.S. in Mechanical Engineering from the University of Wi Wisconsin – Madison in 2007, and an M.S. and a PhD in Mechanical Engineering at Stanford University in 2009 and 2012, respectively. She then worked briefly as a postdoctoral associate at the Massachusetts Institute of Technology before joining the faculty at Purdue University in 2013. Research in the Marconnet Thermal and
Energy Conversion (MTEC) Lab integrates metrology and analysis of underlying transport mechanisms with design and development of nanostructured material s for heat transfer and energy conversion applications.

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Lecture / Discussion Mon, 23 Sep 2019 14:27:34 -0400 2019-09-24T16:00:00-04:00 2019-09-24T17:00:00-04:00 GG Brown Laboratory Mechanical Engineering Lecture / Discussion Amy Marconnet
Causal Inference in Education Research Seminar (CIERS): Scheduling conflict: Effects of overlap in the school and farming calendars on education (September 25, 2019 8:30am) https://events.umich.edu/event/67159 67159-16805234@events.umich.edu Event Begins: Wednesday, September 25, 2019 8:30am
Location: Weill Hall (Ford School)
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 13 Sep 2019 13:57:49 -0400 2019-09-25T08:30:00-04:00 2019-09-25T10:00:00-04:00 Weill Hall (Ford School) Department of Economics Workshop / Seminar economics
DCMB Seminar, "Bioinformatics in Drug Discovery" (September 25, 2019 2:30pm) https://events.umich.edu/event/66407 66407-16734206@events.umich.edu Event Begins: Wednesday, September 25, 2019 2:30pm
Location: Taubman Biomedical Science Research Building
Organized By: DCMB Seminar Series

Abstract:
She’ll be describing the technologies and datasets her team uses to study human disease and develop new and improved treatments for their clients. She’ll cover the applications of traditional transcriptional profiling and sequence analysis as well as datasets and tools developed specifically for therapeutics development including CMap, Project Achilles, PRISM, functional CRISPR screening and others. She’ll also touch on topics like biomarker development, patient selection/stratification and gene therapy development. Along the way, she’ll describe what it’s like to work as a consultant, and how it differs from academic work or direct employment in the pharmaceutical industry.

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Lecture / Discussion Thu, 05 Sep 2019 11:01:32 -0400 2019-09-25T14:30:00-04:00 2019-09-25T15:30:00-04:00 Taubman Biomedical Science Research Building DCMB Seminar Series Lecture / Discussion
Labor Economics: Less is More: Family Size, Early Childhood Environment, and Life-time Human Capital (September 26, 2019 11:30am) https://events.umich.edu/event/67498 67498-16866602@events.umich.edu Event Begins: Thursday, September 26, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 20 Sep 2019 14:40:53 -0400 2019-09-26T11:30:00-04:00 2019-09-26T12:50:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Genes, mechanisms and the possibility of interventional therapies in common craniofacial malformations (September 26, 2019 12:00pm) https://events.umich.edu/event/67496 67496-16866599@events.umich.edu Event Begins: Thursday, September 26, 2019 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

Oral Health Sciences Seminar Series

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Presentation Fri, 20 Sep 2019 14:10:04 -0400 2019-09-26T12:00:00-04:00 2019-09-26T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Presentation Timothy Cox
Deep Learning for Construction Management (September 26, 2019 1:00pm) https://events.umich.edu/event/67469 67469-16857945@events.umich.edu Event Begins: Thursday, September 26, 2019 1:00pm
Location: GG Brown Laboratory
Organized By: Civil and Environmental Engineering

Deep Learning for Construction Management: Earthmoving Productivity Analysis, Bridge Damage Prediction, and Construction Specifications Review

This presentation introduces three representative deep learning research studies that have been conducted by the Construction Innovation Laboratory at Seoul National University for the past five years: site video analysis for automated earthmoving productivity estimation, bridge damage prediction for preventive bridge maintenance, and text mining for automated construction specifications review.

Dr. Seokho Chi is an associate professor in Civil and Environmental Engineering at Seoul National University, Korea. After obtaining B.S. in Civil and Environmental Engineering from Korea University, he received his M.S. and Ph.D. degrees in Civil Engineering from University of Texas at Austin (UT Austin). Before joining Seoul National University in 2013, Dr. Chi worked at Center for Transportation Research in UT Austin, and Queensland University of Technology, Australia.

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Workshop / Seminar Thu, 19 Sep 2019 16:30:44 -0400 2019-09-26T13:00:00-04:00 2019-09-26T14:00:00-04:00 GG Brown Laboratory Civil and Environmental Engineering Workshop / Seminar Bridge
Applied Microeconomics/IO Seminar: Quantifying sources of persistent prescription behavior: Evidence from Belgium (September 27, 2019 10:00am) https://events.umich.edu/event/66706 66706-16770293@events.umich.edu Event Begins: Friday, September 27, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract

Health care policymakers often find it challenging to change physician behavior, as it is highly persistent. Drivers of this persistence are not well understood, but physicians and patients both play a role. I study the importance of both in the prescribing behavior of primary care physicians (PCPs) in Belgium. I exploit a mandate introduced in 2006 that required PCPs to prescribe a minimum percentage of cheap or generic drugs, and analyze the change in PCP prescription habits using administrative data linking 26 million dispensed prescription drugs to 150,000 patients and 45,000 physicians. I find that PCPs exhibit a bias towards prescribing a brand name drug when an equally effective generic is available, and adjust this behavior in response to the mandate without compromising the quality of drugs they prescribe. I show that the type of patient to whom a drug is prescribed matters as well. Compared to patients prescribed medication for the first time, PCPs switch long-time users from branded to generic versions of the same drug at much lower rates, especially when these patients are older or use multiple prescription drugs. This suggests that there is a cost to switching between drugs and that it varies by patient characteristics. Using an instrumental variables framework, I estimate that switching a patient from a brand name to generic version of the same drug indeed comes at a cost, measured with decreased medication adherence. I develop a structural model of prescription behavior to quantify the relative importance of physician bias and patient considerations in PCP prescribing behavior, and find they are about equally important. Using this model, I show that the introduction of a Mandatory Generic Substitution policy may decrease overall welfare as a result of patient considerations. This suggests that policy efforts aimed at changing physician behavior should also consider potentially negative health impacts on patients.

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Workshop / Seminar Mon, 23 Sep 2019 14:59:35 -0400 2019-09-27T10:00:00-04:00 2019-09-27T11:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Michael Woodroofe Lecture Series: Cun-Hui Zhang, Distinguished Professor, Department of Statistics and Biostatistics, Rutgers University (September 27, 2019 10:00am) https://events.umich.edu/event/63882 63882-15977784@events.umich.edu Event Begins: Friday, September 27, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

We consider several problems in areas where Michael Woodroofe has made seminal contributions to. In higher criticism, we develop a one-sided sequential probability ratio test based on the ordered p-values to achieve optimal detection of rare and weak signals. This makes an interesting connection to the test of power one and nonlinear renewal theorem. In multiple isotonic regression, a block estimator is developed to attain minimax rate for a wide range of signal-to-noise ratio, to achieve adaptation to the parametric root-n rate up to a logarithmic factor in the case where the unknown mean is piecewise constant, and to achieve adaptation in variable selection. In uncertainty quantification, we develop second order Stein formulas for statistical inference in nonparametric and high-dimensional problems. Applications of the second order Stein method include exact formulas and upper bounds for the variance of risk estimators and risk bounds for regularized or shape constrained estimators and related degrees of freedom adjustments and confidence regions.

*Hors d'oeuvres immediately following in 337 West Hall (Don Meyer Commons)

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Workshop / Seminar Tue, 24 Sep 2019 09:54:20 -0400 2019-09-27T10:00:00-04:00 2019-09-27T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Zhang,Cun-Hui
MFG Research Seminar: Cloud-Driven Manufacturing: Opportunities and Challenges (September 27, 2019 11:00am) https://events.umich.edu/event/67605 67605-16900794@events.umich.edu Event Begins: Friday, September 27, 2019 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Abstract
For many years now, my students and I have developed several solutions to enable cost-effective deployments in the cloud of low-latency highly-available services. Based on this work, in this talk, my goals are two-fold.

First, I will give an overview of how some of my group's work, as well as other related research from computer science researchers, can be leveraged to enable cloud-driven control of manufacturing devices, i.e., how CS research can be used for improved manufacturing.

Second, in the context of smart manufacturing, I will describe the challenges in applying the approaches traditionally used by computer science researchers. In particular, I will argue that many of the principles that underlie use of the cloud will need to be rethought, and the domain of smart manufacturing presents an exciting new frontier for distributed systems research. I will then show some preliminary work done in collaboration with Prof. Okwudire on the application of cloud computing to the control of manufacturing machines.

Bio
Harsha V. Madhyastha is an Associate Professor in Computer Science and Engineering at the University of Michigan. His research interests span all facets of scalable, fault-tolerant, performant, and privacy-preserving networked systems. His work has resulted in award papers at several top-tier conferences and also received the IRTF's Applied Networking Research Prize on multiple occasions. He is the recipient of Google Faculty Research awards, a NetApp Faculty Fellowship, a Facebook Faculty Award, and an NSF CAREER award.

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Presentation Tue, 24 Sep 2019 15:15:03 -0400 2019-09-27T11:00:00-04:00 2019-09-27T12:00:00-04:00 Chrysler Center Integrative Systems + Design Presentation Harsha Madhyastha
Economics at Work (September 27, 2019 1:00pm) https://events.umich.edu/event/65833 65833-16660095@events.umich.edu Event Begins: Friday, September 27, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Jodi Schenck manages Citi’s North American Corporate Foreign Exchange Sales and Solutions business. In this role, she is responsible for all aspects of Citi’s Corporate FX business in North America, including Sales, Risk Management Solutions, Electronic Solutions, and the supervision over these activities. Jodi’s teams are responsible for advising multinational corporations on foreign exchange risk management and solutioning.

For 5 years prior to this role, Jodi ran the Global Corporate FX eSolutions business which embeds Citi’s electronic solutions into client FX processes. Prior to that, Jodi was responsible for all M&A and episodic currency risk advisory for Citi’s Corporate and Private Equity clients.

Jodi represents Citi and the FXLM business on the board of the Federal Reserve’s Foreign Exchange Committee (FXC). In addition, she is heavily involved in recruiting and diversity efforts at Citi.



Economics@Work (Econ 208) is an invited alumni speaker series that allows students to discover the wide array of career paths available to economics majors and the role economics could play in their careers. In Economics@Work, undergraduates are offered a regular opportunity to network and interact with alumni from the Department of Economics. You’ll discover that economists are engaged in a wide array of professions from investment banking, finance and government, to legislation, advocacy, and online sales and marketing, among many others. This one-credit (credit/no credit) course meets eight (possibly nine) times during the semester. Sessions include a presentation and time for questions. They are followed by a reception in the Foster Library, allowing time to network with speakers.

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Mon, 23 Sep 2019 09:15:10 -0400 2019-09-27T13:00:00-04:00 2019-09-27T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory (September 27, 2019 2:30pm) https://events.umich.edu/event/65832 65832-16660094@events.umich.edu Event Begins: Friday, September 27, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 27 Aug 2019 08:43:50 -0400 2019-09-27T14:30:00-04:00 2019-09-27T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Motivated Errors (September 30, 2019 11:45am) https://events.umich.edu/event/65834 65834-16660106@events.umich.edu Event Begins: Monday, September 30, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract:

In three sets of experiments involving over 3300 individuals, we show that agents motivated to be selfish or to hold egoistic beliefs make systematic errors that appear to be driven by cognitive limitations. We further show that that these errors are eliminated (or dramatically reduced) when self-serving motives are removed. Put differently, we find that individuals make “motivated errors” — they act as if they are cognitively limited, but only when it is self-serving to do so.

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Workshop / Seminar Tue, 27 Aug 2019 10:50:23 -0400 2019-09-30T11:45:00-04:00 2019-09-30T12:45:00-04:00 North Quad Department of Economics Workshop / Seminar economics
Public Finance: The Economic Consequences of Being Denied an Abortion (September 30, 2019 4:00pm) https://events.umich.edu/event/67502 67502-16866608@events.umich.edu Event Begins: Monday, September 30, 2019 4:00pm
Location:
Organized By: Department of Economics

Abstract:

Restrictions on abortion are pervasive, yet relatively little is known about the effect of being denied an abortion on women who seek one while pregnant. This paper evaluates the economic consequences of being denied an abortion on the basis of gestational age of the pregnancy. Our analysis relies on new linkages to administrative data on ten years of credit reports for participants in the Turnaway Study, the first study to collect high-quality, longitudinal data on women receiving or being denied a wanted abortion. The study recruited women seeking an abortion at 30 health providers located in 21 states who fell in to one of two groups: the first group included women with pregnancies close to the facility's gestational age limit who received a wanted abortion (Near Limit Abortion Group), while the second group was women with pregnancies just over the facility's gestational age limit who were turned away without receiving an abortion (Turnaway Group). Our analysis compares differences in credit report outcomes for these two groups for 3 years prior and up to 5 years following the intended abortion using an event study design. We find that the trajectories for these outcomes are similar for the two groups of women during the pre-period. However, following their visit to the abortion provider, we find evidence of a large and persistent increase in financial distress for the women who were denied an abortion that is sustained for the 6 years following the intended abortion.

With Diana G. Foster (UCSF) and Laura R. Wherry (UCLA)

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Workshop / Seminar Mon, 23 Sep 2019 10:10:19 -0400 2019-09-30T16:00:00-04:00 2019-09-30T17:30:00-04:00 Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Jim Bagian, MD, PE (September 30, 2019 4:30pm) https://events.umich.edu/event/67675 67675-16915705@events.umich.edu Event Begins: Monday, September 30, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

It has been twenty years since patient safety was thrust into the public and professional consciousness of healthcare. Despite the attention that has been given this complex topic in both the professional and lay press the progress towards making patient safety a real priority in healthcare has been limited. Transforming healthcare so that patient safety becomes an inherent property embedded in the very fabric of the organization requires the adoption of a variety of values, techniques, and processes that are continually  reinforced by the words and deeds of leadership at all levels. Critical elements and methods for achieving this goal will be discussed.

Dr. James P. Bagian is the Director of the Center for Healthcare Engineering and Patient Safety and is a Professor in the  Department of Anesthesiology in the Medical School and the College of Engineering at the University of Michigan. Previously, he served as the first Director of the VA National Center for Patient Safety (NCPS) and the first Chief Patient Safety Officer for the Department of Veterans Affairs from 1999 to 2010 where he developed numerous patient safety related tools and programs that have been adopted nationally and internationally. Dr. Bagian served as a NASA astronaut and is a veteran of two Space Shuttle missions and was an investigator of both the Challenger and Columbia Space Shuttle mishaps. Presently, he is applying systems engineering approaches to the analysis of medical adverse events and the development and implementation of systems-based corrective actions that will enhance patient safety primarily through preventive means. He received his B.S. in mechanical engineering from Drexel University and his M.D. from Jefferson Medical College at Thomas Jefferson University. He is a Fellow of the Aerospace Medical Association, a member of the National Academy of Engineering, the Institute of Medicine, and has received numerous awards for his work in the field of patient safety and aerospace medicine.

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: http://www.bme.umich.edu/about/directions.php.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 26 Sep 2019 09:37:33 -0400 2019-09-30T16:30:00-04:00 2019-09-30T18:00:00-04:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Jim Bagian
Cellular Lipid Homeostasis: From Lipid Droplets to Lipotoxicity- Department of Biological Chemistry Seminar (October 1, 2019 12:00pm) https://events.umich.edu/event/67253 67253-16829027@events.umich.edu Event Begins: Tuesday, October 1, 2019 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

The Department of Biological Chemistry is hosting a seminar given by Dr. James Olzmann, Associate Professor in the Department of Nutritional Sciences and Toxicology, UC Berkeley on Tuesday October 1, 2019. The seminar will take place at 12:00 noon in North Lecture Hall, MS II

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Workshop / Seminar Mon, 16 Sep 2019 11:24:45 -0400 2019-10-01T12:00:00-04:00 2019-10-01T13:00:00-04:00 Medical Science Unit II Biological Chemistry Workshop / Seminar James Olzmann
Mechanical Engineering Seminar Series (October 1, 2019 4:00pm) https://events.umich.edu/event/67537 67537-16892234@events.umich.edu Event Begins: Tuesday, October 1, 2019 4:00pm
Location: GG Brown Laboratory
Organized By: Mechanical Engineering

Impacting Healthcare Costs with a University of Michigan innovation – FlexDex

Dr. Kent Bowden, General Surgery, Cadillac Hospital, Munson Healthcare System

Abstract
Driven by minimally invasive procedures that require intensive suturing, the adoption of robotics in general surgery has accelerated dramatically in spite of high costs and steep learning curve. While big hospitals are able to absorb the cost of owning and maintaining multi-million dollar DaVinci surgical robots and associated infrastructure, small community hospitals face a difficult decision.

In this talk, I will present this dilemma faced by Cadillac Hospital, which serves the rural community of about 80,000 residents in seven counties in northern Michigan. A few years ago, we had to decide to either invest significant time, money, and personnel in creating and running a robotics program, or lose our patients and surgeons to bigger hospitals and medical centers. This would be a loss for the
local community, economy, and quality of living. Instead, we looked for alternate options. There weren’t many but the most promising one seemed to be a technology from our own state – FlexDex – created at the University of Michigan.

I will describe how I ended up adopting FlexDex and pioneering complex surgical procedures with it just as they would be performed on the DaVinci surgical robot but at much lower costs to the hospital. I have now performed over four hundred FlexDex procedures including hernia repair, colon resection, fundoplication, and hysterectomy. The savings from this decision and the “notoriety” that this brought us has expanded our surgical efficiency as well as capabilities.

FlexDex is now spreading all over the world and is being adopted in urology, gynecology, cardiothoracic, bariatric, and whipple procedures among others. I will discuss the future potential of this technology in providing greater access to minimally invasive surgery world-wide at an affordable cost. I will also discuss ongoing technology needs and challenges that remain in surgery that might
inspire new research and innovation at universities.

Bio
Dr. Kent Bowden, D.O. is a General Surgeon at Cadillac Hospital, Munson Healthcare. He trained at the College of Osteopathic Medicine, Michigan State University and graduated in 2005. He completed his Residency at Ingham Regional Medical Center in Lansing, MI in 2010, and joined private practice in a rural hospital where he could have a broad-spectrum practice. His objective as a surgeon is to
provide cost-effective, personalized and world-class care to patients in his local community. In addition to pioneering cases with FlexDex, he enjoys coaching basketball at his children's school and spending time outdoors with his family. Dr. Bowden is a Fellow of the American College of Osteopathic Surgeons (FACOS).

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Lecture / Discussion Mon, 23 Sep 2019 13:10:54 -0400 2019-10-01T16:00:00-04:00 2019-10-01T17:00:00-04:00 GG Brown Laboratory Mechanical Engineering Lecture / Discussion Dr. Kent Bowden
Health, Nature & Our Built Environment: Change through Radical Collaborations (October 2, 2019 12:00pm) https://events.umich.edu/event/67640 67640-16909312@events.umich.edu Event Begins: Wednesday, October 2, 2019 12:00pm
Location: Public Health I (Vaughan Building)
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

The Integrated Health Sciences Core of the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) presents an Environmental Research Seminar featuring John Spengler, Akira Yamaguchi Professor of Environmental Health and Human Habitation, and Director of the JPB Environmental Health Fellowship Program at the Harvard T.H. Chan School of Public Health.

Dr. Spengler has conducted research on personal monitoring, air pollution health effects, indoor air pollution, and a variety of environmental sustainability issues. Several of his investigations have focused on housing design and its effects on ventilation rates, building materials’ selection, energy consumption, and total environmental quality in homes.

Spengler chaired the committee on Harvard Sustainability Principles; and served on Harvard’s Greenhouse Gases Taskforce to develop the University’s carbon reduction goals and strategies, as well as Harvard’s Greenhouse Gases Executive Committee. He serves on the National Academies’ Health and Medicine Division “Roundtable on Environmental Health Sciences, Research and Medicine”. Previously he chaired the National Academies’ NRC “Green Schools: Attributes for Health and Learning” committee and the IOM “Effect of Climate Change on Indoor Air Quality and Public Health” committee; and he has served as an advisor to the World Health Organization on indoor air pollution, personal exposure and air pollution epidemiology. He now serves on the Alfred P. Sloan Foundation’s Chemistry of Indoor Environments advisory committee.

In 2003, Spengler received a Heinz Award for the Environment; in 2007, the Air & Waste Management Association Lyman Ripperton Environmental Educator Award; in 2008, the Max von Pettenkofer Award for distinguished contributions in indoor air science from the International Society of Indoor Air Quality & Climate’s Academy of Fellows; and in 2015, the ASHRAE Environmental Health Award.

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Lecture / Discussion Wed, 25 Sep 2019 13:47:35 -0400 2019-10-02T12:00:00-04:00 2019-10-02T12:50:00-04:00 Public Health I (Vaughan Building) Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Jack Spengler
MIPSE Seminar | Plasma Diagnostics Package for Studying High-Power Hall Thrusters in Flight (October 2, 2019 3:30pm) https://events.umich.edu/event/65965 65965-16676357@events.umich.edu Event Begins: Wednesday, October 2, 2019 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
NASA is preparing to demonstrate high-power electric propulsion on the Power and Propulsion Element (PPE), the first element of a human-operated Gateway station that will orbit the Moon. The Hall thrusters (HTs) being flown on the PPE will operate at three times the power of current state-of-the-art HTs and utilize magnetic shielding, which greatly increase the wear life of the thrusters. Associated with these advances in technical capability are uncertainties regarding the plasma properties of the exhaust plume, particularly the low density plume exiting sideways from the thrusters. To better predict the erosive power of the plasma plume and how the plume might interact with the PPE and future spacecraft, NASA is flying the Plasma Diagnostics Package (PDP). The PDP data will refine plasma models for predicting the behavior of high-power HT systems on future missions. This presentation will describe a brief history of the PDP project, basic Hall thruster plume physics, the plasma physics behind the PDP sensor design, and current status of the PDP project.

About the Speaker:
Wensheng Huang received a PhD in Aerospace Engineering from the University of Michigan in 2011 and BS degrees in Mechanical and Nuclear Engineering from the University of California, Berkeley in 2006. His dissertation was on the use of optical diagnostics to study Hall thruster erosion under the tutelage of Prof. Alec D. Gallimore. Wensheng is currently a researcher in the Electric Propulsion Systems branch at the NASA Glenn Research Center. He is the Principle Investigator for the Plasma Diagnostics Package (PDP) that will be flying on the Power and Propulsion Element (PPE), the first element of NASA's Moon-orbiting Gateway. He is also the diagnostics lead for the Solar Electric Propulsion Hall thruster project, which will also be flying on the PPE.

The seminar will be web-simulcast. To view the simulcast, please follow this link:
https://mipse.my.webex.com/mipse.my/j.php?MTID=mb945413a4f95eb01ac7ca576b226e306
Meeting number: 295 354 766
Password: MIPSE19

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Lecture / Discussion Mon, 30 Sep 2019 11:47:37 -0400 2019-10-02T15:30:00-04:00 2019-10-02T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Wensheng Huang
Special Joint Lecture (MICHR and DCMB) (October 2, 2019 4:00pm) https://events.umich.edu/event/67257 67257-16829032@events.umich.edu Event Begins: Wednesday, October 2, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract: Dr. Haendel’s vision is to weave together healthcare systems, basic science research, and patient generated data through development of data integration technologies and innovative data capture strategies. The Monarch Initiative is an international consortium dedicated to integrating human and organismal genotype-phenotype data and the development of deep phenotyping techniques. This talk will focus on the use of ontologies to support knowledge and data integration across disciplinary boundaries. Strategies for how to reconcile different terminologies and examples of harmonized semantic structures for anatomy, phenotype, and disease will be discussed. Finally, we will discuss the use of these ontological resources to populate graph structures and their use to aid mechanism discovery and rare disease diagnosis.

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Lecture / Discussion Mon, 16 Sep 2019 11:53:44 -0400 2019-10-02T16:00:00-04:00 2019-10-02T17:00:00-04:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
BME 500: Jon Rowley, Ph.D. (October 3, 2019 9:00am) https://events.umich.edu/event/67721 67721-16924403@events.umich.edu Event Begins: Thursday, October 3, 2019 9:00am
Location: Chrysler Center
Organized By: Biomedical Engineering

BME 500 Seminar Series



Thursday, October 3rd, 2019

9:00 – 10:00 a.m.

133 Chrysler



Jon Rowley, Ph.D.

Founder of RoosterBio Inc.

University of Michigan Alumnus


“Radically Simplifying hMSC Manufacturing Scale-up and Regenerative Medicine Product Development (and Building a Business around Regenerative Medicine Manufacturing Technology)”



Abstract:

Human Mesenchymal Stem/Stromal Cells (hMSCs) and extracellular vesicles (hMSC-EVs) are leading platforms for development of regenerative medicine therapies. Multiple bottlenecks exist during discovery, product development, manufacturing process development, and cGMP manufacturing leading to timelines from discovery through first in man testing often averaging 7-11 years. RoosterBio has developed and commercialized novel hMSC bioprocess systems that are designed for rapid process development and cGMP tech transfer to radically reduce development timelines to as little as 2-4 years. Requirements for implementation of scalable bioreactor production systems will also be addressed, and data will be presented from 50L scale microcarrier-based processes with CQAs for both hMSCs and EVs.

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Lecture / Discussion Fri, 27 Sep 2019 10:00:06 -0400 2019-10-03T09:00:00-04:00 2019-10-03T10:00:00-04:00 Chrysler Center Biomedical Engineering Lecture / Discussion BME Event
Statistics Department Seminar Series: Long Nguyen, Associate Professor, Department of Statistics, University of Michigan (October 4, 2019 10:00am) https://events.umich.edu/event/63883 63883-15977785@events.umich.edu Event Begins: Friday, October 4, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

We study posterior contraction behaviors for parameters of interest in the context of Bayesian mixture modeling, where the number of mixing components is unknown while the model itself may or may not be correctly specified. Posterior contraction rates are given under optimal transport distances for two popular types of prior specification: one requires explicitly a prior distribution on the number of mixture components, and a nonparametric Bayesian approach which places a prior on the space of mixing distributions. Paraphrasing George Box, all mixture models are misspecified, but some may be more interpretable than others — it will be shown that the modeling choice of kernel density functions plays perhaps the most impactful roles in determining the posterior contraction rates in the misspecified situations. Drawing on concrete parameter estimation rates I will highlight some aspects about the interesting tradeoffs between model expressiveness and interpretability that a statistical modeler must negotiate in the rich world of mixture modeling.
This work is joint with Aritra Guha and Nhat Ho.

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Workshop / Seminar Thu, 26 Sep 2019 14:21:24 -0400 2019-10-04T10:00:00-04:00 2019-10-04T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Nguyen,Long
MCDB Seminar: RNA Binding Proteins, Cancer-Induced Cachexia--Potential Therapy (October 4, 2019 12:00pm) https://events.umich.edu/event/67346 67346-16839903@events.umich.edu Event Begins: Friday, October 4, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Mohammed Akaaboune

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Workshop / Seminar Tue, 17 Sep 2019 15:29:02 -0400 2019-10-04T12:00:00-04:00 2019-10-04T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar collage of micrographs with MCDB letters
Social, Behavioral & Experimental Economics (SBEE): Lying and Deception in Games (October 7, 2019 11:45am) https://events.umich.edu/event/66212 66212-16719592@events.umich.edu Event Begins: Monday, October 7, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

This article proposes definitions of lying, deception, and damage in strategic settings. Lying depends on the existence of accepted meanings for messages, but does not require a model of how the audience responds to messages. Deception does require a model of how the audience interprets messages, but does not directly refer to consequences. Damage requires consideration of the consequences of messages. Lies need not be deceptive. Deception does not require lying. Lying and deception are compatible with equilibrium. I give conditions under which deception must be damaging.

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Workshop / Seminar Tue, 03 Sep 2019 14:59:27 -0400 2019-10-07T11:45:00-04:00 2019-10-07T12:45:00-04:00 North Quad Department of Economics Workshop / Seminar economics
Public Finance: Why Do Borrowers Default on Mortgages? A New Method For Causal Attribution (October 7, 2019 4:00pm) https://events.umich.edu/event/65844 65844-16660107@events.umich.edu Event Begins: Monday, October 7, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come

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Workshop / Seminar Thu, 26 Sep 2019 14:38:55 -0400 2019-10-07T16:00:00-04:00 2019-10-07T17:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Emily Mower Provost, PhD (October 7, 2019 4:30pm) https://events.umich.edu/event/67940 67940-16969030@events.umich.edu Event Begins: Monday, October 7, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Engineering approaches to human behavior analysis are complicated by the lack of a one-to-one mapping between the behavioral cues that an individual generates and how an external observer interprets those cues. This many-to-many mapping injects noise into both the data and ground truth. As a result, many of the models and assumptions used in traditional machine learning and signal processing must be used with caveats or adapted to meet the needs of this domain. I will discuss our work on algorithmic approaches to characterize and predict how humans perceive signals that modulate spoken communication, focusing on emotion and mood. I will highlight our efforts in tracking mood for individuals with bipolar disorder. These technologies have the potential to forward diagnosis and treatment by providing constrained, repeatable, and easily modifiable assessment protocols, objective measures, and interaction scenarios.

Emily Mower Provost is an Associate Professor in Computer Science and Engineering at the University of Michigan. She received her Ph.D. in Electrical Engineering from the University of Southern California (USC), Los Angeles, CA in 2010. She is a member of Tau-Beta-Pi, Eta-Kappa-Nu, and a member of IEEE and ISCA. She has been awarded a National Science Foundation CAREER Award (2017), a National Science Foundation Graduate Research Fellowship (2004-2007), the Herbert Kunzel Engineering Fellowship from USC (2007-2008, 2010-2011), the Intel Research Fellowship (2008-2010), the Achievement Rewards For College Scientists (ARCS) Award (2009 – 2010), and the Oscar Stern Award for Depression Research (2015). She is a co-author on the paper, "Say Cheese vs. Smile: Reducing Speech-Related Variability for Facial Emotion Recognition," winner of Best Student Paper at ACM Multimedia, 2014, and a co-author of the winner of the Classifier Sub-Challenge event at the Interspeech 2009 emotion challenge. Her research interests are in human-centered speech and video processing, multimodal interfaces design, and speech-based assistive technology. The goals of her research are motivated by the complexities of the perception and expression of human behavior. 

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: http://www.bme.umich.edu/about/directions.php.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 02 Oct 2019 14:59:11 -0400 2019-10-07T16:30:00-04:00 2019-10-07T18:00:00-04:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Emily Mower Provost, PhD
Great Lakes Seminar - Dr. Joannes Westerink - Tuesday, October 8, 10:30-11:30 am (October 8, 2019 10:30am) https://events.umich.edu/event/67919 67919-16966899@events.umich.edu Event Begins: Tuesday, October 8, 2019 10:30am
Location: Off Campus Location
Organized By: Cooperative Institute for Great Lakes Research (CIGLR)

Please join us for a Great Lakes Seminar!
Tuesday, October 8, 10:30-11:30 am

NOAA Great Lakes Environmental Research Laboratory
4840 S State Rd, Ann Arbor

Remote participation via webinar is available: https://register.gotowebinar.com/register/5551628124438203405

Presenter: Joannes Westerink, Department of Civil & Environmental Engineering & Earth Sciences, University of Notre Dame

Title: Towards Heterogeneous Process, Scale, and Model Coupling in Simulating the Hydrodynamics of the Coastal Ocean

About the speaker:
Joannes Westerink is the Joseph and Nona Ahearn Professor of Computational Science and Engineering and the Henry J. Massman Chair of the Department of Civil and Environmental Engineering and Earth Sciences at the University of Notre Dame. He obtained his B.S. (1979) and M.S. (1981) degrees in Civil Engineering at the State University of New York at Buffalo and Ph.D. (1984) degree in Civil Engineering from the Massachusetts Institute of Technology.

Westerink develops high resolution heterogeneous unstructured mesh, multi-physics, multi-scale hydrodynamic codes and models for the hydrodynamics of the coastal ocean and has successfully transitioned these to practitioners for a wide range of applications including the analysis and design of major flood control projects and coastal ocean water level forecasting systems. Westerink has pioneered the successful use of global to channel scale highly heterogeneous unstructured mesh coastal ocean models with mesh resolution varying by up to four orders of magnitude. This encompasses the optimization of algorithms; development of high performance codes in vector and parallel computing environments; the linkages of circulation models to weather and short wind wave models; model verification, validation, and uncertainty quantification; and the application of codes to oceans, continental shelf regions, estuaries, rivers, and coastal flood plains. Westerink is the co-developer, with Rick Luettich of the University of North Carolina at Chapel Hill and Clint Dawson of the University of Texas at Austin, of the widely used ADCIRC finite element based shallow water equation code. ADCIRC has evolved into a community based coastal hydrodynamics code with wide ranging applications within academia, government, and the private sector worldwide. The U.S. Army Corps of Engineers, the Federal Emergency Management Agency and the National Oceanic and Atmospheric Administration all use ADCIRC in support of coastal water level and flooding analyses and forecasts.

Westerink was a team co-lead in the U.S. Army’s Interagency Performance Evaluation Taskforce (IPET) investigation of the Hurricane Katrina (2005) flooding failures in Louisiana. He led ADCIRC storm surge model development for the USACE’s New Orleans and vicinity Hurricane and Storm Damage Risk Reduction System. He also led the ADCIRC model development for the FEMA Flood Insurance Studies in coastal Louisiana and Texas. He served as a commissioner on the Southeast Louisiana Flood Protection Authority and has served as an advisor for the UNESCO Joint WMO-IOC Technical Commission for Oceanography and Marine Meteorology on Enhancing Forecasting Capabilities for North Indian Ocean Storm Surges. He currently serves as an International Advisory Board Member of CIGIDEN, Chile’s National Research Center for Integrated Natural Disaster Management.

Westerink’s current research includes: the development of high order h-p adaptive Discontinuous Galerkin based coastal circulation codes; incorporating phase resolving wave processes including run-up directly into circulation codes; understanding resonant basin and shelf modes and shelf dissipation processes; incorporating local rainfall and small scale channel routing capabilities into shallow water based codes; sea ice interaction with wind waves and circulation; and downscaling global ocean models into global high resolution coastal models to account for baroclinicity and sea level fluctuations. Current applications regions include developing the next generation of ESTOFS water level forecast models for NOAA focusing on Puerto Rico and the U.S. Virgin Islands; the U.S. East and Gulf coasts, and Alaska.

About the presentation:
Hurricane wind wave, storm surge, and current environments in the coastal ocean and adjacent coastal floodplain are characterized by their high energy and by their spatial variability. These processes impact offshore energy assets, navigation, ports and harbors, deltas, wetlands, and coastal communities. The potential for an enormous catastrophic impact in terms of loss of life and economic losses is substantial.

Computational models for wind waves and storm driven currents and surge must provide a high level of grid resolution, fully couple the wind wave and long wave processes, and perform quickly for risk assessment, flood mitigation system design, and forecasting purposes. In order to accomplish this, high performance scalable codes are essential. To this end, we have developed an MPI based domain decomposed unstructured grid framework that minimizes global communications, efficiently handles localized sub-domain to sub-domain communication, applies a local inter-model paradigm with all model to model communications being kept on identical cores for sub-domains, and carefully manages output by assigning specialized cores for this purpose. Continuous Galerkin (CG) and Discontinuous Galerkin (DG) implementations are examined. Performance of explicit and implicit implementations of the wave-current coupled system on up to 32,000 cores for various platforms is evaluated.

The system has been extensively validated with an ever increasing amount of wave, water level and current data that has being collected for recent storms including Hurricanes Katrina (2005), Rita (2005), Gustav (2008), Ike (2008), and Sandy (2012). The modeling system helps understand the physics of hurricane storm surges including processes such as geostrophically driven forerunner, shelf waves that propagate far away from the storm, wind wave – surge interaction, surge capture and propagation by protruding deltaic river systems, the influence of storm size and forward speed, and frictionally controlled inland penetration.

These models are being applied by the US Army Corps of Engineers (USACE) in the development of the recently completed hurricane risk reduction system in Southern Louisiana as well as for the development of FEMA Digital Flood Insurance Rate Maps (DFIRMS) for Texas, Louisiana, Mississippi, and other Gulf and Atlantic coast states. NOAA applies the models in extra-tropical and tropical storm surge forecasting.

Current development is focused on incorporating a wider range of physics affecting coastal and inland water levels as well as forces on infrastructure including large scale baroclinically driven processes, rainfall runoff in upland areas and on the coastal floodplain, and wave run-up. This is accomplished with an interleafing framework in which heterogeneous models focused on a select range of processes are coupled over the same domain and/or specific targeted equations that are dynamically assigned to changing portions of the domain as appropriate to the prevailing flow conditions. This is all done in a dynamically load balanced framework. Algorithmic development is focused on DG solvers, ideally suited for the associated strongly advective flows, allow super-parametric elements for p=1 and p=2 and iso-parametric elements for p=3 in order to achieve improved convergence rates and overall runtime efficiency, and allow for the selection of localized physics on the elemental level.

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Workshop / Seminar Wed, 02 Oct 2019 10:43:17 -0400 2019-10-08T10:30:00-04:00 2019-10-08T11:30:00-04:00 Off Campus Location Cooperative Institute for Great Lakes Research (CIGLR) Workshop / Seminar Seminar flyer
“Every Sector is Public Health Sector": Building Capacity to Address Environmental Health Inequities (October 8, 2019 12:00pm) https://events.umich.edu/event/68017 68017-16983971@events.umich.edu Event Begins: Tuesday, October 8, 2019 12:00pm
Location: Public Health I (Vaughan Building)
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Dr. Sampson will discuss three examples of capacity-building to build and translate evidence, including:
1) a youth environmental health academy in Dearborn, MI;
2) a health impact assessment for the Gordie Howe International Bridge at the Detroit-Windsor border;
3) her work with APHA to convene environmental health and justice leaders—all to advance evidence-based policies that address environmental health inequities.

Natalie Sampson is an Assistant Professor of Public Health at UM-Dearborn, where she teaches courses in environmental health, health promotion, and community organizing. Grounded primarily in Southeast Michigan, she studies transportation and land use planning, green stormwater infrastructure, vacant land reuse, and climate change planning efforts, particularly their implications for health. She applies participatory research approaches with diverse partners using a broad methodological toolkit, including photovoice, concept mapping, and health impact assessment. In 2017, Sampson received the American Public Health Association (APHA)’s Rebecca Head Award, which recognizes “an outstanding emerging leader from the environmental field working at the nexus of science, policy, and environmental justice.”

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Lecture / Discussion Fri, 04 Oct 2019 11:08:30 -0400 2019-10-08T12:00:00-04:00 2019-10-08T12:50:00-04:00 Public Health I (Vaughan Building) Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Oct 8 Natalie Sampson Seminar
ChE Seminar Series: Brendan Harley (October 8, 2019 1:30pm) https://events.umich.edu/event/65445 65445-16597589@events.umich.edu Event Begins: Tuesday, October 8, 2019 1:30pm
Location:
Organized By: Chemical Engineering

>This Seminar will be held in the North Campus Research Complex, Building 32, Auditorium


"Building tissues:engineering complexity through biomaterial design"

ABSTRACT

Advances in the fields of tissue engineering and regenerative medicine require biomaterials that instruct, rather than simply permit, a desired cellular response. A major challenge is the striking cellular and structural heterogeneity of the tissues and organs in our bodies, which can be hierarchical, graded, and heterogeneous over multiple length and time scales. Prof. Harley’s research program is developing approaches to pattern biomaterials at structural and biomolecular scales to replicate these complex environments. We provide new insight regarding the degree of biomaterial complexity required to investigate cellular processes related to development, disease, and regeneration. I will describe a collagen biomaterial being developed to regenerate craniomaxillofacial bones and musculoskeletal insertions. We are using bioinspired design motifs to create composite materials that instruct desired cell activities while retaining mechanical competence required for clinical translation. I will also describe a gelatin hydrogel platform and microfluidic forming techniques we have developed to create libraries of optically-translucent tissue microenvironments containing patterns of cell, matrix, biomolecular, and metabolic cues. We are using these engineered microenvironments to culture hematopoietic stem cells and patient-derived glioblastoma specimens, the most common and lethal form of brain cancer. I will highlight work that employs this platform to regulate processes such as stem cell self-renewal vs. quiescence; cell-cell signaling and remodeling of perivascular environments; as well as to identify microenvironmental signals driving cancer cell invasion and therapeutic resistance.

SHORT BIO

Brendan Harley is a Professor and Robert W. Schaefer Faculty Scholar in the Dept. of Chemical and Biomolecular Engineering at the University of Illinois at Urbana-Champaign. He received a B.S. in Engineering Sciences from Harvard University (2000), a Sc.D. in Mechanical Engineering from MIT (2006), and performed postdoctoral studies at the Joint Program for Transfusion Medicine at Children’s Hospital Boston (2006 – 2008). His research group develops biomaterial platforms to dynamically regulate cell behavior for applications in musculoskeletal regeneration, hematopoietic stem cell biomanufacturing, as well as to investigate endometrial pathologies and invasive brain cancer. He has received funding from the NSF, NIH, American Cancer Society, the U.S. Army, and the AO Foundation. Prof. Harley co-founded a regenerative medicine company, Orthomimetics Ltd., to commercialize a biomaterial for osteochondral regeneration (global patent protection; CE Mark approval; 150+ patient Phase I clinical trial).

Dr. Harley has received a number of awards and honors including an NSF CAREER award (2013), the Young Investigator Award from the Society for Biomaterials (2014), as well as college and campus-level research, teaching, and promotion awards (U. Illinois). He is an elected Fellow of the American Association for the Advancement of Science (2014) and the American Institute for Medical and Biological Engineering (2018).

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Lecture / Discussion Wed, 21 Aug 2019 18:05:27 -0400 2019-10-08T13:30:00-04:00 2019-10-08T14:30:00-04:00 Chemical Engineering Lecture / Discussion
Department of Computational Medicine & Bioinformatics Weekly Wednesday Seminar (October 9, 2019 4:00pm) https://events.umich.edu/event/68092 68092-17009821@events.umich.edu Event Begins: Wednesday, October 9, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk Title: "Controlling dynamic ensembles: From cells to societies"

Abstract: Natural and engineered systems that consist of populations of isolated or interacting dynamical components exhibit levels of complexity that are beyond human comprehension. These complex systems often require an appropriate excitation, an optimal hierarchical organization, or a periodic dynamical structure, such as synchrony, to function as desired or operate optimally. In many application domains, e.g., neurostimulation in brain medicine and nuclear magnetic resonance spectroscopy and imaging in quantum control, control and observation can only be implemented at the population level, through broadcasting a single input signal to all the systems in the population and through collecting aggregated system-level measurements of the population, respectively. These limitations give rise to challenging problems and new control paradigms involving underactuated manipulation of dynamic ensembles. This talk will address theoretical and computational challenges for targeted coordination of both isolated and networked ensemble systems arising in diverse areas at different scales. Both model-based and data-driven approaches for learning, decoding, control, and computation of dynamic structures and patterns in ensemble systems will be presented. Practical control designs, including synchronization waveforms for pattern formation in complex networks and optimal pulses in quantum control, will be illustrated along with their experimental realizations. Lastly, future directions and opportunities in Systems and Controls will be discussed.

3:45 p.m. - Light Refreshments Served
4:00 p.m. - Lecture

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Lecture / Discussion Mon, 07 Oct 2019 10:26:01 -0400 2019-10-09T16:00:00-04:00 2019-10-09T17:00:00-04:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
BME 500: Erin Purcell, Ph.D. (October 10, 2019 9:00am) https://events.umich.edu/event/67722 67722-16924404@events.umich.edu Event Begins: Thursday, October 10, 2019 9:00am
Location: Chrysler Center
Organized By: Biomedical Engineering

TBA

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Lecture / Discussion Fri, 27 Sep 2019 10:06:59 -0400 2019-10-10T09:00:00-04:00 2019-10-10T10:00:00-04:00 Chrysler Center Biomedical Engineering Lecture / Discussion BME Event
International Economics, Macroeconomics (October 10, 2019 11:30am) https://events.umich.edu/event/66214 66214-16719594@events.umich.edu Event Begins: Thursday, October 10, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come

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Workshop / Seminar Thu, 03 Oct 2019 11:24:59 -0400 2019-10-10T11:30:00-04:00 2019-10-10T12:50:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
CONFIDENT PLURALISM (October 10, 2019 8:00pm) https://events.umich.edu/event/68166 68166-17020449@events.umich.edu Event Begins: Thursday, October 10, 2019 8:00pm
Location: Power Center for the Performing Arts
Organized By: Asian InterVarsity Christian Fellowship

Join us for a conversation at the Power Center on Thursday, October 10 at 8 PM with John Inazu and Kelly Dunlop. They'll discuss the themes of John's recent book, Confident Pluralism: Survivng and Thriving through Deep Difference. Is there a way past our seemingly irresolvable differences of beliefs, values, and identities toward a healthier future of tolerance, patience, and empathy. John is associate professor of law and religion at Washington University in St. Louis. Kelly is the Associate Director of the Center for Campus Initiative at the University of Michigan. This dialogue is co-sponsored by the Veritas Forum and the Association of Religious Counselors.

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Lecture / Discussion Tue, 08 Oct 2019 14:49:28 -0400 2019-10-10T20:00:00-04:00 2019-10-10T22:00:00-04:00 Power Center for the Performing Arts Asian InterVarsity Christian Fellowship Lecture / Discussion Crop of the Event Poster
Applied Microeconomics/IO Seminar: The Role of Advertising in New Drug Diffusion and Negotiated Prices (October 11, 2019 10:00am) https://events.umich.edu/event/67332 67332-16839871@events.umich.edu Event Begins: Friday, October 11, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 17 Sep 2019 12:50:16 -0400 2019-10-11T10:00:00-04:00 2019-10-11T11:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Samory Kpotufe, Associate Professor, Department of Statistics, Columbia University (October 11, 2019 10:00am) https://events.umich.edu/event/63884 63884-15977786@events.umich.edu Event Begins: Friday, October 11, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract:
The problem of transfer and domain adaptation is ubiquitous in machine learning and concerns situations where predictive technologies, trained on a given source dataset, have to be transferred to a new target domain that is somewhat related. For example, transferring voice recognition trained on American English accents to apply to Scottish accents, with minimal retraining. A first challenge is to understand how to properly model the ‘distance’ between source and target domains, viewed as probability distributions over a feature space.

In this talk we will argue that various existing notions of distance between distributions turn out to be pessimistic, i.e., these distances might appear high in many situations where transfer is possible, even at fast rates. Instead we show that some new notions of distance tightly capture a continuum from easy to hard transfer, and furthermore can be adapted to, i.e., do not need to be estimated in order to perform near-optimal transfer. Finally we will discuss near-optimal approaches to minimizing sampling of target data (e.g. sampling Scottish speech), when one already has access to a given amount of source data (e.g. American speech).

This talk is based on some joint work with G. Martinet, and ongoing work with S. Hanneke.

Short-Bio:
Samory Kpotufe is Associate Professor in Statistics at Columbia University. He works in machine learning, with an emphasis on nonparametric methods and high dimensional statistics. Generally, his interests are in understanding basic learning scenarios under practical constraints from modern application domains. He has previously held positions at the Max Planck Institute in Germany, the Toyota Technological Institute at Chicago, and Princeton University.

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Workshop / Seminar Wed, 02 Oct 2019 14:33:27 -0400 2019-10-11T10:00:00-04:00 2019-10-11T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Kpotufe,Samory
MCDB Seminar: Temperature Sensing and Preference in Drosophila (October 11, 2019 12:00pm) https://events.umich.edu/event/67350 67350-16839923@events.umich.edu Event Begins: Friday, October 11, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Monica Dus

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Workshop / Seminar Tue, 17 Sep 2019 16:11:36 -0400 2019-10-11T12:00:00-04:00 2019-10-11T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar cartoon of large Drosophila fly and city in flames
UMMA Pop Up: Davis & Brown: Banjo + Cello Duo (October 13, 2019 3:00pm) https://events.umich.edu/event/68059 68059-16988233@events.umich.edu Event Begins: Sunday, October 13, 2019 3:00pm
Location: Museum of Art
Organized By: University of Michigan Museum of Art (UMMA)

Zachary Brown is a cellist, hailing from Brentwood, NY.  Zachary began the cello age the age of thirteen. He completed a double degree in cello performance and jazz studies from Ithaca College in 2016 as well as a masters in cello performance from SUNY Purchase in 2019. He has appeared as a guest artist and has given instructional workshops on “chopping” and improvisation at the New Directions Cello festival as well in at the Ithaca Winter Strings Festival.    Matthew Davis is an up and coming banjoist in the world of new acoustic music, and elsewhere. His influences include artists like Béla Fleck, Donald Fagen, the Punch Brothers, Julian Lage, and many others. Growing up playing piano, it wasn’t until Matthew was 12 years old when he decided to pick up the banjo for the first time. Since then, he has continued to improve himself as a musician with a strong desire to find ways to take the banjo into new musical areas. Matthew’s list of achievements include the 2016 National Banjo Champion, 2016 & 2017 Acoustic Music Seminar Alumni, and the 2017 Rockygrass Banjo Champion. He currently studies jazz at the University of Michigan School of Music, Theatre & Dance in Ann Arbor, MI.

For more about this dynamic duo, visit www.westboundsituation.com

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Performance Tue, 08 Oct 2019 12:17:33 -0400 2019-10-13T15:00:00-04:00 2019-10-13T16:00:00-04:00 Museum of Art University of Michigan Museum of Art (UMMA) Performance Museum of Art
Cholesterol and Phospholipis Metabolism in Physiology and Disease- Annual William E.M. Lands Lectureship in Biological Chemistry (October 15, 2019 12:00pm) https://events.umich.edu/event/67920 67920-16966900@events.umich.edu Event Begins: Tuesday, October 15, 2019 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Peter Tontonoz will deliver the 15th annual William E.M. Lands Lecture on the Biochemical Basis for the Physiology of Essential Nutrients. Dr. Tontonoz is a Professor of Pathology and Laboratory Medicine at the University of California, Los Angeles.

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Lecture / Discussion Wed, 02 Oct 2019 10:37:58 -0400 2019-10-15T12:00:00-04:00 2019-10-15T13:00:00-04:00 Medical Science Unit II Biological Chemistry Lecture / Discussion Tontonoz
MIPSE Seminar | Hydroxyl Radicals in Gas-Liquid Water Plasma Reactors (October 16, 2019 3:30pm) https://events.umich.edu/event/65966 65966-16678369@events.umich.edu Event Begins: Wednesday, October 16, 2019 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Electrical discharge plasmas formed in and in contact with liquid water are of interest for applications in chemical, biomedical, agricultural, electrical, and materials engineering. Analysis of plasmas interacting with liquids is challenging due to the complex relations among the important chemical and physical processes. In addition to the various ways (e.g., AC, DC, pulsed, RF, MW) and geometries to generate a plasma contacting a liquid, the formation of plasma at a gas-liquid interface also depends on the gas composition, liquid properties (e.g., conductivity), and the nature of the molecular transport processes (e.g., hydrodynamics of two-phase flow, energy transport, and mass transfer) at the interface. To address these challenges and focus on the specific case of filamentary plasma channels propagating along a gas-liquid water interface, we have constructed a gas-liquid plasma reactor that enables control of many of these variables. The plasma-liquid interactions have been characterized for chemical reactions including hydrogen peroxide formation, oxidation of hydrocarbons, combined plasma degradation of organic contaminants, nitrogen oxide formation, and hydroxyl radical generation. In this presentation, we will discuss some of the key findings. Comparison will be made of OH generation by gas-water plasma reactors with competing methods such as UV, radiation chemistry, ultrasound, and chemical oxidation methods.

About the Speaker: Dr. Bruce R. Locke earned his B.E. in Chemical Engr. and Environmental & Water Resources from Vanderbilt U. in 1980, MS. from the U. of Houston in 1982, and PhD in Chemical Engr. from North Carolina State U. in 1989. During 1982-86 he was at the Research Triangle Institute working on analysis of submicron aerosol particles in microelectronics manufacturing. He has been a professor in the Dept. of Chemical and Biomedical Engr. at Florida State University (FSU) since 1989 where he was department chair during 2005-12. He was an Associate Provost at FSU during 2012-18 responsible for international programs, and was interim dean of the FAMU-FSU College of Engineering in 2015-16. He was named FSU Distinguished University Research Professor in 2010. Dr. Locke has published 137 journal papers, 8 book chapters and holds 6 patents. He has been visiting professor in Japan, France, and China, and was a Fulbright Research Scholar at the Czech Academy of Sciences in 2017-18. He is Fellow of the American Inst. of Chemical Engineers and is co-Editor-in-Chief of Plasma Chemistry and Plasma Processing. His research interests include plasma reaction engineering for chemical synthesis and environmental pollution control, emphasizing gas-liquid plasma reactor development.

The seminar will be web-simulcast. To view the simulcast, please follow this link:
https://mipse.my.webex.com/mipse.my/j.php?MTID=m85f0e1b661dbc2c8253eddda8b069848
Meeting number: 627 088 372
Password: MIPSE

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Lecture / Discussion Tue, 15 Oct 2019 10:32:37 -0400 2019-10-16T15:30:00-04:00 2019-10-16T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Bruce Locke
Department of Computational Medicine & Bioinformatics Weekly Seminar (October 16, 2019 4:00pm) https://events.umich.edu/event/68138 68138-17011980@events.umich.edu Event Begins: Wednesday, October 16, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk Title: "3D genome structure as a tool to understand the impact of somatic and germline sequence variants"

Abstract: The 3-dimensional organization of DNA inside of the nucleus impacts a variety of cellular processes, including gene regulation. Furthermore, it is apparent that somatic structural variants that affect how chromatin is organized in 3D can have a major impact on gene regulation and human disease. However, such structural variants in the context of cancer genomes are abundant, and predicting the consequence of any individual somatic mutation on 3D genome structure and gene expression is challenging. In addition, we are severely limited with regard to tools that can be used to study 3D folding of the genome in vivo in actual human tumor or tissue samples. Our lab has developed several approaches to address these challenges. We have taken a pan-cancer approach to identify loci in the genome that are affected by structural variants that alter 3D genome structure, and we have identified numerous loci with recurrent 3D genome altering mutations. We have also used genome engineering to create novel structural variants to better understand what types of mutations are actually capable of altering 3D genome structure and gene regulation. Finally, we have also developed novel tools to study 3D genome structure in vivo in complex tissue samples. We believe that these approaches will be critical for improving our understanding of how non-coding sequence variants can affect 3D genome structure and gene regulation, with the ultimate goal of understanding how these events affect human physiology.

3:45 pm - Light Refreshments Served
4:00 pm - Lecture

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Lecture / Discussion Mon, 07 Oct 2019 16:39:45 -0400 2019-10-16T16:00:00-04:00 2019-10-16T17:00:00-04:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
International Economics (October 17, 2019 11:30am) https://events.umich.edu/event/68300 68300-17043867@events.umich.edu Event Begins: Thursday, October 17, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 11:36:11 -0400 2019-10-17T11:30:00-04:00 2019-10-17T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Law and Economics: Bargaining in the Shadow of the Judge (October 17, 2019 4:30pm) https://events.umich.edu/event/68322 68322-17045999@events.umich.edu Event Begins: Thursday, October 17, 2019 4:30pm
Location: Jeffries Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 15:17:02 -0400 2019-10-17T16:30:00-04:00 2019-10-17T18:30:00-04:00 Jeffries Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Genevera Allen, Associate Professor of Electrical and Computer Engineering, Statistics and Computer Science, Rice University (October 18, 2019 10:00am) https://events.umich.edu/event/63885 63885-15977787@events.umich.edu Event Begins: Friday, October 18, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract:
Data integration, or the strategic analysis of multiple sources of data simultaneously, can often lead to discoveries that may be hidden in individual analyses of a single data source. In this talk, we present several new techniques for data integration of mixed, multi-view data where multiple sets of features, possibly each of a different domain, are measured for the same set of samples. This type of data is common in heathcare, biomedicine, national security, multi-senor recordings, multi-modal imaging, and online advertising, among others. In this talk, we specifically highlight how mixed graphical models and new feature selection techniques for mixed, mutli-view data allow us to explore relationships amongst features from different domains. Next, we present new frameworks for integrated principal components analysis and integrated generalized convex clustering that leverage diverse data sources to discover joint patterns amongst the samples. We apply these techniques to integrative genomic studies in cancer and neurodegenerative diseases to make scientific discoveries that would not be possible from analysis of a single data set.

Short-Bio:
Genevera Allen is an Associate Professor of Electrical and Computer Engineering, Statistics and Computer Science at Rice University and an investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and Baylor College of Medicine. She is also the Founder and Faculty Director of the Rice Center for Transforming Data to Knowledge, informally called the Rice D2K Lab. Dr. Allen's research focuses on developing statistical machine learning tools to help scientists make reproducible data-driven discoveries. Her work lies in the areas of interpretable machine learning, optimization, data integration, modern multivariate analysis, and graphical models with applications in neuroscience and bioinformatics. Dr. Allen is the recipient of several honors including a National Science Foundation Career award, the George R. Brown School of Engineering's Research and Teaching Excellence Award at Rice University, and in 2014, she was named to the "Forbes '30 under 30': Science and Healthcare" list. Dr. Allen received her PhD in statistics from Stanford University (2010), under the mentorship of Prof. Robert Tibshirani, and her bachelors, also in statistics, from Rice University (2006).

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Workshop / Seminar Thu, 10 Oct 2019 13:56:18 -0400 2019-10-18T10:00:00-04:00 2019-10-18T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Allen
MCDB Seminar: Monoterpene Volatile Biosynthesis in Rose Scented Geranium (October 18, 2019 12:00pm) https://events.umich.edu/event/67356 67356-16839924@events.umich.edu Event Begins: Friday, October 18, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Eran Pichersky

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Workshop / Seminar Tue, 17 Sep 2019 16:19:55 -0400 2019-10-18T12:00:00-04:00 2019-10-18T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Glandular trichomes Pelargonium graveolens
Economics at Work (October 18, 2019 1:00pm) https://events.umich.edu/event/66215 66215-16719597@events.umich.edu Event Begins: Friday, October 18, 2019 1:00pm
Location:
Organized By: Department of Economics

Ridhi Patel is a principal at a boutique management consulting firm who specializes in optimization, strategy development, and implementation/execution. In this role, she is responsible for driving each of her projects to delivery and providing her client with the best solution to their concerns. At Trexin, she has worked on several projects for one of the country’s largest health insurance providers within their IT Infrastructure, Information Security, Government Health Programs, Corporate Services, and Finance divisions.

Within Trexin, she is a senior member of the strategy execution practice and manages the cybersecurity practice. Prior to Trexin, Ridhi worked in strategic sourcing and implemented massive non-labor cost-reduction initiatives for healthcare providers. Her first foray into consulting was with American Express where she worked with Fortune 500 clients and implemented cost-saving strategies.
Economics@Work (Econ 208) is an invited alumni speaker series that allows students to discover the wide array of career paths available to economics majors and the role economics could play in their careers. In Economics@Work, undergraduates are offered a regular opportunity to network and interact with alumni from the Department of Economics. You’ll discover that economists are engaged in a wide array of professions from investment banking, finance and government, to legislation, advocacy, and online sales and marketing, among many others. This one-credit (credit/no credit) course meets eight (possibly nine) times during the semester. Sessions include a presentation and time for questions. They are followed by a reception in the Foster Library, allowing time to network with speakers.



Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Wed, 16 Oct 2019 14:09:48 -0400 2019-10-18T13:00:00-04:00 2019-10-18T14:30:00-04:00 Department of Economics Workshop / Seminar economics
Economic Theory: Steady-State Equilibria in Anonymous Repeated Games, I: Trigger Strategies in General Stage Games (October 18, 2019 2:30pm) https://events.umich.edu/event/66217 66217-16719599@events.umich.edu Event Begins: Friday, October 18, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

We introduce a new model of repeated games in large populations with random matching, overlapping generations, and limited records of past play. We prove that steady-state equilibria exist under general conditions on records. We then focus on “trigger-strategy” equilibria. When the updating of a player’s record can depend on the actions of both players in a match, steady-state equilibria in trigger strategies can support the play of a wide range of actions, including any action that Pareto-dominates a static Nash equilibrium. When updates can depend only on a player’s own actions, fewer actions can be supported by steady-state equilibria. We provide sufficient conditions for trigger equilibria to support a given action, along with somewhat more permissive necessary conditions. When players have access to a form of decentralized public randomization, the sufficient conditions expand to match the necessary conditions.
joint with Daniel Clark and Drew Fudenberg

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Workshop / Seminar Fri, 18 Oct 2019 14:20:35 -0400 2019-10-18T14:30:00-04:00 2019-10-18T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Exploration in Teams and the Encouragement Effect: Theory and Experimental Evidence (October 21, 2019 11:45am) https://events.umich.edu/event/68301 68301-17043868@events.umich.edu Event Begins: Monday, October 21, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

This paper analyzes a two-person, two-stage model of sequential exploration, where both information and payoff externalities exist, and tests the derived hypotheses in the laboratory. We theoretically show that even when agents are self-interested and perfectly rational, the information externality induces an encouragement effect: a positive effect of first-player exploration on the optimality of the second-player exploring as well. When agents have other-regarding preferences and imperfectly optimize, the encouragement effect is strongest. The explorative nature of the game raises the expected surplus compared to a payoff equivalent public goods game. We empirically confirm our main theoretical predictions using a novel experimental paradigm. Our findings are relevant for motivating and managing groups and teams innovating not only for private but also, and especially so, for public goods.

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Workshop / Seminar Fri, 11 Oct 2019 11:43:13 -0400 2019-10-21T11:45:00-04:00 2019-10-21T12:45:00-04:00 North Quad Department of Economics Workshop / Seminar economics
Public Finance: Measuring Racial Discrimination in Pretrial Bail Decisions (October 21, 2019 4:00pm) https://events.umich.edu/event/66761 66761-16776774@events.umich.edu Event Begins: Monday, October 21, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

Large racial disparities exist in many settings, including criminal justice and healthcare delivery systems, but it is unclear whether these disparities reflect omitted variables or racial discrimination. We develop a quasi-experimental approach to measure and characterize discrimination in the context of pretrial bail decisions. Race-specific average treatment effects (of pretrial release on subsequent misconduct) are used to purge omitted variables bias from conventional benchmarking regressions, isolating legally-unwarranted release rate disparities among black and white defendants with the same potential for pretrial misconduct. Leveraging the quasi-random assignment of bail judges in New York City, we find that approximately 70 percent of the average release rate disparity between observationally-equivalent white and black defendants is due to discrimination. Nearly all judges discriminate against black defendants, with higher levels of discrimination among judges who are older, more stringent, and less exposed to black cases. To explore the form that this discrimination takes, we develop and estimate a hierarchical marginal treatment effects model in which judges can differ in their rankings of defendant misconduct risk (in violation of the conventional monotonicity assumption). We find evidence of both racial bias and statistical discrimination, with the latter arising from both lower mean risk and more precise risk signals for white defendants.

joint with David Arnold and Will Dobbie

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Workshop / Seminar Tue, 08 Oct 2019 09:20:39 -0400 2019-10-21T16:00:00-04:00 2019-10-21T17:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Health, History, Demography & Development (H2D2) (October 22, 2019 11:30am) https://events.umich.edu/event/68621 68621-17105387@events.umich.edu Event Begins: Tuesday, October 22, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Hannah will be presenting Abandoning Obsolete Technologies in Medicine: Preliminary Evidence.

Abstract: The extent that medical practice relies on evidence varies by specialty. Practices that become popular based on promising case studies are especially susceptible to evidence reversal. Medical reversal occurs when a procedure that is common in clinical practice is shown to be ineffective or even harmful. Failure to quickly abandon reversed practices dampens productivity in the medical sector and results in wasteful spending. I present preliminary evidence about the speed of de-adoption, using the procedures of vertebroplasy and percutaneous coronary interventions as case studies.

Marlous will be presenting The Great Convergence: Skill Accumulation and Mass Education in Africa and Asia, 1870-2010.

Abstract: While human capital has gained prominence in new vintages of growth theory, economists have struggled to find the positive externalities of mass education in developing economies. We shed new light on the economic significance of the global ‘schooling revolution’ by looking at a different indicator of human capital accumulation – the relative price of skilled labor – and placing it in a long-term global perspective. Based on a new wage dataset we constructed for various blue- and white-collar occupations in 50 African and Asian countries between 1870-2010, we reveal that skill-premiums have fallen dramatically everywhere in the course of the 20th century, and that they have now converged with levels that dominated in the West already for centuries. While such a ‘great convergence’ in skill-premiums is not a sufficient condition for Schumpeterian growth by itself, the growing availability of affordable skills is a necessary condition. Our findings therefore shed a more optimistic light on the long-term economic gains of mass education in the global South than standard growth regressions have hitherto done.

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Workshop / Seminar Fri, 18 Oct 2019 16:16:51 -0400 2019-10-22T11:30:00-04:00 2019-10-22T12:50:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Prediction Error & Model Evaluation for Space-Time Downscaling: case studies in air pollution during wildfires (October 22, 2019 1:00pm) https://events.umich.edu/event/68191 68191-17026797@events.umich.edu Event Begins: Tuesday, October 22, 2019 1:00pm
Location: Public Health I (Vaughan Building)
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

ABSTRACT:
Public Health Scientists use prediction models to downscale (i.e., interpolate) air pollution exposure where monitoring data is insufficient. This exercise aims to obtain estimates at fine resolutions, so that exposure data may reliably be related to health outcomes. In this setting, substantial research efforts have been dedicated to the development of statistical models capable of integrating heterogenous information to obtain accurate prediction: statistical downscaling models, land use regression, as well as machine learning strategies. However, when presented with the tasks of choosing between models, or averaging models, we find that our understanding of model performance in the absence of independent statistical replications remains insufficient. This lecture is motivated by several studies of air pollution (PM 2.5 and ground-level ozone) during wildfires. We review the basis for cross validation as a strategy for the estimation of the expected prediction error. As these performance measure play a crucial role in model selection and averaging we present a formal characterization of the estimands targeted by different data subsetting strategies, and explore their performance in engineered data settings. A final analysis and a warning about preference inversion is presented in relation to the a 2008 wildfire event in Northern California.

BIO:
Dr. Telesca is Associate Professor of Biostatistics at the University of California Los Angeles. He received a Ph.D. in Statistics from the University of Washington and spent two years at the University of Texas M.D. Anderson Cancer Center as a postdoctoral fellow. His research interests include Bayesian methods in multivariate statistics, functional data analysis, statistical methods in bio- and nano-informatics. Dr. Telesca is a member of the California NanoSystems Institute, the UCLA Jonsson Comprehensive Cancer Center and principal data scientist at Lucid Circuit Inc.

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Lecture / Discussion Wed, 09 Oct 2019 09:51:07 -0400 2019-10-22T13:00:00-04:00 2019-10-22T14:30:00-04:00 Public Health I (Vaughan Building) Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Donatello Telesca Environmental Statistics Day Lecture
ChE Seminar Series: Eric Shusta (October 22, 2019 1:30pm) https://events.umich.edu/event/65576 65576-16615783@events.umich.edu Event Begins: Tuesday, October 22, 2019 1:30pm
Location:
Organized By: Chemical Engineering

>This Seminar will be held in the North Campus Research Complex, Building 32, Auditorium

ABSTRACT

Antibody Engineering Strategies to Overcome the Blood-brain barrier

Millions of people worldwide are afflicted with neurological diseases such as Parkinson's disease, Alzheimer's disease, brain cancer, and cerebral AIDS. Although many new drugs are being developed to combat these and other brain diseases, few new treatments have made it to the clinic.  The impermeable nature of the brain vasculature, also known as the blood-brain barrier (BBB), is at least partially responsible for the paucity of new brain therapeutics.  As examples, approximately 98% of small molecule pharmaceuticals do not enter the brain after intravenous administration, and the BBB prevents nearly all protein and gene medicines from entering the brain.  Our research group is therefore focused on developing tools for the analysis of the brain drug delivery process and identifying novel strategies for circumventing this transport barrier.  This presentation will detail our recent work focused on overcoming BBB restrictions on brain drug delivery. To this end, we are mining large antibody libraries to identify antibodies that can target and act as artificial substrates for endogenous receptor-mediated BBB nutrient transport systems and ferry drug cargo into the brain. In addition, the BBB can be disrupted in certain disease conditions such as brain tumors. For these applications, we are identifying antibodies capable of targeting brain extracellular matrix to leverage this pathological BBB disruption for drug accumulation.   After conjugation to drug payloads that can include small molecules or biologics, we have demonstrated that both classes of antibodies have the potential to deliver medicines to the brain.

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Lecture / Discussion Wed, 21 Aug 2019 18:03:38 -0400 2019-10-22T13:30:00-04:00 2019-10-22T14:30:00-04:00 Chemical Engineering Lecture / Discussion
Department of Computational Medicine & Bioinformatics Weekly Seminar Series (October 23, 2019 4:00pm) https://events.umich.edu/event/68168 68168-17020453@events.umich.edu Event Begins: Wednesday, October 23, 2019 4:00pm
Location:
Organized By: DCMB Seminar Series

Talk Title: "Chromatin accessibility signatures of immune system aging"

Abstract: Aging is linked to deficiencies in immune responses and increased systemic inflammation. To unravel regulatory programs behind these changes, we profiled peripheral blood mononuclear cells (PBMCs) from young and old individuals (n=77) using ATAC-seq and RNA-seq technologies and analyzed these data via systems immunology tools. First, we described an epigenomic signature of immune system aging, with simultaneous systematic chromatin closing at promoters and enhancers associated with T cell signaling. This signature was primarily borne by memory CD8+ T cells, which exhibited an aging-related loss in IL7R activity and IL7 responsiveness. More recently to uncover the impact of sex on immune system aging, we studied PBMCs from 194 healthy adults (100 women, 94 men) ranging from 22-93 years old using ATAC-seq, RNA-seq, and flow cytometry technologies. These data revealed a shared epigenomic signature of aging between sexes composed of declines in naïve T cell functions and increases in monocyte and cytotoxic cell functions. Despite similarities, these changes were greater in magnitude in men. Additionally, we uncovered male-specific decreases in expression/accessibility of B-cell associated loci. Trajectory analyses revealed that age-related epigenomic changes were more abrupt at two timepoints in the human lifespan. The first timepoint was similar between sexes in terms of timing (early forties) and magnitude. In contrast, the latter timepoint was earlier (~5 years) and more pronounced in men (mid-sixties versus late-sixties). Unexpectedly, differences between men and women PBMCs increased with aging, with men having higher monocyte and pro-inflammatory activity and lower B/T cell activity compared to women after 65 years of age. Our study uncovered which immune cell functions and molecules are differentially affected with age between sexes, including the differences in timing and magnitude of changes, which is an important step towards precision medicine in older adults.

3:45 pm - Light refreshments served
4:00 pm - Lecture

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Lecture / Discussion Tue, 08 Oct 2019 15:12:18 -0400 2019-10-23T16:00:00-04:00 2019-10-23T17:00:00-04:00 DCMB Seminar Series Lecture / Discussion
Macroeconomics (October 23, 2019 4:00pm) https://events.umich.edu/event/68255 68255-17037409@events.umich.edu Event Begins: Wednesday, October 23, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 22 Oct 2019 14:40:24 -0400 2019-10-23T16:00:00-04:00 2019-10-23T17:20:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
International Economics & Labor Economics Seminar (October 24, 2019 11:30am) https://events.umich.edu/event/68302 68302-17043869@events.umich.edu Event Begins: Thursday, October 24, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:38:06 -0400 2019-10-24T11:30:00-04:00 2019-10-24T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Applied Microeconomics/IO Seminar: Bidding for Firms: Subsidy Competition in the U.S. (October 25, 2019 10:00am) https://events.umich.edu/event/66702 66702-16770287@events.umich.edu Event Begins: Friday, October 25, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

In the U.S., states compete to attract firms by offering discretionary subsidies, but little is known about how states choose their subsidy offers, and whether such subsidies affect firms' location choices. In this paper, I use an oral ascending (English) auction to model the subsidy ``bidding" process and estimate the efficiency of subsidy competition. The model allows state governments to value both the direct and indirect (spillover) job creation of firms when submitting bids, and firms to take both subsidies offered and state characteristics into account when choosing their location. To estimate my model, I hand-collect a new and unique dataset on state incentive spending and subsidy deals from 2002-2016. I estimate both the distribution of states' (revealed) valuations for firms that rationalizes observed subsidies, and firms' valuations for state characteristics. In order to allow states to value potential spillovers, I estimate the effect of subsidy-winning firms' locations on the entry decision of smaller firms, using a discrete choice entry model. I provide the first empirical evidence that states use subsidies to help large firms internalize the positive spillovers, in the form of indirect job creation, they have on the states. Moreover, subsidies have a sizable effect on firm locations. In particular, I find that without subsidies approximately 68% of firms would locate in a different state, and the number of anticipated indirect jobs created would decrease by 32%. With subsidies, total welfare (the sum of state valuations and firm profits) increases by 22%, but this welfare gain is captured entirely by the firms.

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Workshop / Seminar Mon, 09 Sep 2019 15:43:03 -0400 2019-10-25T10:00:00-04:00 2019-10-25T11:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Jie Peng, Professor, Department of Statistics, UC Davis (October 25, 2019 10:00am) https://events.umich.edu/event/63886 63886-15977788@events.umich.edu Event Begins: Friday, October 25, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Diffusion MRI is an in vivo and non invasive imaging technology that uses water diffusion as a proxy to probe architecture of biological tissues. Diffusion MRI technology has been widely used for white matter fiber tracts reconstruction. It also has many clinical applications in neurodegenerative diseases such as Alzheimer's.
In this talk, We discuss various statistical models for analyzing diffusion MRI data. These models aim to elucidate local (voxel-level) neuronal fiber organizations based on D-MRI measurements, which are in turn used as inputs in tracking algorithms to reconstruct white matter fiber tracts. We focus on their capability in resolving crossing fibers -- a major challenge in diffusion MRI data analysis, and their computational scalability. We also discuss spatial smoothing schemes that leverage information from neighboring brain voxels. These methods are applied to both synthetic experiments and to real D-MRI data from large imaging consortium.

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Workshop / Seminar Wed, 16 Oct 2019 15:19:27 -0400 2019-10-25T10:00:00-04:00 2019-10-25T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Jie Peng
Macroeconomics (October 25, 2019 11:30am) https://events.umich.edu/event/68263 68263-17037419@events.umich.edu Event Begins: Friday, October 25, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Thu, 10 Oct 2019 13:20:05 -0400 2019-10-25T11:30:00-04:00 2019-10-25T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
MCDB Seminar: Telomerase RNA Biogenesis: Human Genetics to Therapeutic Prospects (October 25, 2019 12:00pm) https://events.umich.edu/event/67357 67357-16839925@events.umich.edu Event Begins: Friday, October 25, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: JK Nandakumar

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Workshop / Seminar Tue, 17 Sep 2019 16:28:46 -0400 2019-10-25T12:00:00-04:00 2019-10-25T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar micrograph of teleomeres
Economics at Work (October 25, 2019 1:00pm) https://events.umich.edu/event/68592 68592-17105348@events.umich.edu Event Begins: Friday, October 25, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

avid Saferstein is the co-founder, co-owner and Chief Executive Officer of Titan Capital ID, LLC (“Titan”), one of the largest private real estate lenders in the New York City metropolitan area. Since becoming CEO of Titan Capital in January of 2005, Mr. Saferstein has helped Titan originate over $3 Billion in bridge loans. Titan has offices in New York City, Connecticut and Miami. Mr. Saferstein oversees all aspects of the business including but not limited to loan origination, loan servicing, asset allocation, investor relations, credit facility relations with FDIC banks and property management of real estate owned.

Prior to joining Titan Capital, Mr. Saferstein founded G&D Trading Company, a broker/dealer specializing in derivatives trading with seats on the American Stock Exchange, Pacific Coast Exchange, Philadelphia Stock Exchange, COMEX, & CBOE. Mr. Saferstein is also the founder of the Saferstein Family Charitable Foundation which provides annual grants, research awards and educational support for Masters level programs for 5th year fellowship and other young investigators in the field of IBD and other gastrointestinal diseases.

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Tue, 22 Oct 2019 13:55:05 -0400 2019-10-25T13:00:00-04:00 2019-10-25T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory (October 25, 2019 2:30pm) https://events.umich.edu/event/68618 68618-17105384@events.umich.edu Event Begins: Friday, October 25, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 14:15:30 -0400 2019-10-25T14:30:00-04:00 2019-10-25T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Equity Concerns are Narrowly Framed (October 28, 2019 11:45am) https://events.umich.edu/event/68303 68303-17043871@events.umich.edu Event Begins: Monday, October 28, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract
We show that individuals narrowly bracket their equity concerns. Across six experiments including 2,360 subjects, individuals equalize components of payoffs rather than overall payoffs. When earnings are comprised of “small tokens” worth 1 cent and “large tokens” worth 2 cents, subjects frequently equalize the distribution of small (or large) tokens rather than equalizing total earnings. When payoffs are comprised of time and money, subjects similarly equalize the distribution of time (or money) rather than total payoffs. In addition, subjects are more likely to equalize time than money. These findings can help explain a variety of behavioral phenomena including the structure of social insurance programs, patterns of public good provision, and why transactions that turn money into time are often deemed repugnant.

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Workshop / Seminar Fri, 11 Oct 2019 11:50:54 -0400 2019-10-28T11:45:00-04:00 2019-10-28T12:45:00-04:00 North Quad Department of Economics Workshop / Seminar economics
Public Finance & Labor Economics: A Unified Welfare Analysis of Government Policies (October 28, 2019 4:00pm) https://events.umich.edu/event/66768 66768-16776775@events.umich.edu Event Begins: Monday, October 28, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

We conduct a comparative welfare analysis of 133 historical policy changes over the past half-century in the United States, focusing on policies in social insurance, education and job training, taxes and cash transfers, and in-kind transfers. For each policy, we use existing causal estimates to calculate both the benefit that each policy provides its recipients (measured as their willingness to pay) and the policy’s net cost, inclusive of long-term impacts on the government’s budget. We divide the willingness to pay by the net cost to the government to form each policy’s Marginal Value of Public Funds, or its “MVPF”. Comparing MVPFs across policies provides a unified method of assessing their impact on social welfare. Our results suggest that direct investments in low-income children’s health and education have historically had the highest MVPFs, on average exceeding 5. Many such policies have paid for themselves as governments recouped the cost of their initial expenditures through additional taxes collected and reduced transfers. We find large MVPFs for education and health policies amongst children of all ages, rather than observing diminishing marginal returns throughout childhood. We find smaller MVPFs for policies targeting adults, generally between 0.5 and 2. Expenditures on adults have exceeded this MVPF range in particular if they induced large spillovers on children. We relate our estimates to existing theories of optimal government policy and we discuss how the MVPF provides lessons for the design of future research. All estimates can be also viewed in our interactive web tool at www.policyinsights.org.

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Workshop / Seminar Tue, 08 Oct 2019 09:23:30 -0400 2019-10-28T16:00:00-04:00 2019-10-28T17:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Katie Esper, MPH, MHCDS (October 28, 2019 4:30pm) https://events.umich.edu/event/68702 68702-17138822@events.umich.edu Event Begins: Monday, October 28, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Katie joined the Johns Hopkins University Applied Physics Laboratory (JHU/APL) in 2010 as a health systems engineer after a few years with a healthcare software company. She has worked directly with the military health system implementing multi-site healthcare delivery initiatives and data driven management systems. Katie’s interests are in population need assessments, practice variation studies, and system design for enterprise wide application. Katie is currently the Program Manager of Force Health and Readiness, overseeing the mission of ensuring a ready medical force, a medically ready force, and the delivery of safe reliable care across all operational settings. In this position, Katie is a strategic thought partner for military leaders and oversees a Warfighter Readiness Performance Improvement portfolio of work.

Katie holds a Bachelor’s degree in Industrial and Operations Engineering from the University of Michigan, a Master’s of Public Health from Johns Hopkins Bloomberg School of Public Health (with a focus in Quality, Patient Safety, and Outcomes Research), and a Master’s in Healthcare Delivery Science from Dartmouth College.

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Lecture / Discussion Tue, 22 Oct 2019 15:03:56 -0400 2019-10-28T16:30:00-04:00 2019-10-28T18:00:00-04:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Katie Esper
Complex Systems Seminar | Stephanie Forrest 'The Biology of Software: Evolution, Robustness, Diversity' (October 29, 2019 11:30am) https://events.umich.edu/event/68316 68316-17045998@events.umich.edu Event Begins: Tuesday, October 29, 2019 11:30am
Location: Weiser Hall
Organized By: The Center for the Study of Complex Systems

**Please note, if this room's capacity is exceeded, there will be a simulcast into the next room of talk slides and audio**

Stephanie Forrest is Professor of Computer Science at Arizona State University, where she directs the Biodesign Center for Biocomputation, Security and Society. Her research focuses on the intersection of biology and computation, including cybersecurity, software engineering, and biological modeling.

Abstract:
Software today is a complex adaptive system. Although we think of computer programs as the products of intelligent design, they also evolve inadvertently through the actions of many individual programmers, often leading to unanticipated consequences. Similarly, economic and political incentives produce arms races between competitors and adversaries, which in turn have shaped the cyber landscape.

The talk will give examples of evolution, robustness and diversity in the context of software, describing how these concepts provide new insights and suggest new approaches to problems such as repairing software bugs and cybersecurity. It will present recent results on the mutational robustness of software and describe a new algorithm for bug repair that leverages neutral mutations.


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Prior to joining ASU in 2017, Professor Forrest was at the University of New Mexico and served as Dept. Chair 2006-2011. She is a member of the Santa Fe Institute External Faculty and 2013-2014 served at the U.S. Dept. of State as a Senior Science Advisor for cyberpolicy. She was educated at St. John's College (B.A.) and the University of Michigan (M.S. and Ph.D. in Computer Science).

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Workshop / Seminar Mon, 28 Oct 2019 13:11:45 -0400 2019-10-29T11:30:00-04:00 2019-10-29T13:00:00-04:00 Weiser Hall The Center for the Study of Complex Systems Workshop / Seminar Stephanie Forrest
Health, History, Demography & Development (H2D2) (October 29, 2019 11:30am) https://events.umich.edu/event/68831 68831-17161711@events.umich.edu Event Begins: Tuesday, October 29, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Shooshan will be presenting Office Visits Preventing Emergency Room Visits: Evidence from the Flint Water Switch.

Abstract: Emergency department visits are costly to providers and to patients. We use the Flint water crisis to test if an exogenous increase in office visits reduced avoidable emergency room visits. In September 2015, citizens in Flint became aware of increased lead levels in their drinking water, resulting from the switch from Lake Huron to the Flint River. Using Medicaid claims for 2013-2016, we find that this information shock increased the share of enrollees with lead tests by 1.7 percentage points. Additionally, it increased office visits immediately following the information shock, then decreased them afterwards. This led to a reduction of 4.9 preventable, non-emergent, and primary care treatable emergency room visits per 1000 eligible children (8.2%). This decrease is present in shifts from emergency room visits to office visits across several common conditions. Our results suggest following lead tests, children were more likely to receive care from the same clinic and that establishing care reduces the likelihood a parent will take their child to receive care at the emergency room for conditions treatable in an office setting. Our results are potentially applicable to any situation in which individuals are induced to seek more care in an office visit setting.

Martha will be presenting Reducing Out-of-Pocket Costs for Contraceptives Increases Use among Low-Income Women.

Abstract: In the U.S., nearly half of pregnancies are unintended, and unintended pregnancies occur twice as often among poor relative than in the U.S. population overall. The cost of effective contraception may be among the most important drivers of unintended pregnancies. Even with generous subsidies under Title X of the Public Health Services Act, the insertion of an IUD at Planned Parenthood costs $223 for uninsured women earning between 100 and 150% of the poverty line. To examine the role of costs in determining the use of contraception, the Michigan Contraceptive Access, Research, and Evaluation Study (M-CARES) has randomized over 1,800 women at Michigan Planned Parenthood (PPMI) clinics to receive vouchers that reduce out-of-pocket costs for contraceptives. Using follow-up surveys and administrative records, we report on how vouchers for contraceptives impacted the use of any birth control the use of long-run acting contraceptives.

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Workshop / Seminar Fri, 25 Oct 2019 10:13:33 -0400 2019-10-29T11:30:00-04:00 2019-10-29T12:50:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
9th Annual Thomas D. Gelehrter M.D. Lecture in Medical Genetics (October 29, 2019 2:00pm) https://events.umich.edu/event/65874 65874-16662158@events.umich.edu Event Begins: Tuesday, October 29, 2019 2:00pm
Location: Taubman Biomedical Science Research Building
Organized By: Department of Human Genetics

Helen H. Hobbs, M.D., is an Investigator of the Howard Hughes Medical Institute and a Professor of Internal Medicine and Molecular Genetics at the University of Texas Southwestern Medical Center. Among Dr. Hobbs’ honors was her election to the National Academy of Medicine in 2004 and National Academy of Sciences in 2007. She received the Breakthrough Prize in Life Sciences and Passano Award (with Jonathan Cohen) in 2016 and the Harrington Prize for Innovation in Medicine in 2018. Dr. Hobbs is recognized for her contributions to the development of new lipid-lowering strategies by identifying genetic variants of large effect in humans. Importantly, her work created a new strategy using human genetics to identify new therapeutic targets for the treatment of complex cardiovascular and metabolic disorders.

This lecture honors Thomas D. Gelehrter, M.D., active emeritus professor and former Chair of the Department of Human Genetics at the University of Michigan.

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Lecture / Discussion Tue, 27 Aug 2019 16:59:30 -0400 2019-10-29T14:00:00-04:00 2019-10-29T17:00:00-04:00 Taubman Biomedical Science Research Building Department of Human Genetics Lecture / Discussion Dr. Helen H. Hobbs
Economic History: Intergenerational Mobility in American History: Accounting for Race and Measurement Error (October 29, 2019 2:30pm) https://events.umich.edu/event/68313 68313-17045991@events.umich.edu Event Begins: Tuesday, October 29, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

A growing body of evidence suggests that intergenerational mobility in the United States has declined over the past 150 years. However, research that finds high relative mobility in America’s past is based on data with few or no black families, and therefore does not account for the limited opportunities available for African Americans. Moreover, historical studies often measure the father’s economic status with error, which biases estimates towards higher mobility. Using new early 20th century data, I show that the persistence of economic status from father to son is over twice as strong after accounting for racial disparities and for measurement error. After addressing these two issues, I estimate that relative mobility has increased over the 20th century. The results imply that there is greater equality of opportunity today than in the early 20th century, mostly because opportunity in the past was never that equal.

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Workshop / Seminar Thu, 17 Oct 2019 09:51:40 -0400 2019-10-29T14:30:00-04:00 2019-10-29T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Macroeconomics (October 30, 2019 4:00pm) https://events.umich.edu/event/68840 68840-17163791@events.umich.edu Event Begins: Wednesday, October 30, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 25 Oct 2019 12:30:13 -0400 2019-10-30T16:00:00-04:00 2019-10-30T17:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
BME Seminar: Raj Kothapalli, Ph.D. (October 31, 2019 9:00am) https://events.umich.edu/event/68891 68891-17188750@events.umich.edu Event Begins: Thursday, October 31, 2019 9:00am
Location: Chrysler Center
Organized By: Biomedical Engineering

Photoacoustic imaging (PAI) gained significant attention of biomedical community as it provides optical
absorption contrast based functional and molecular information of very deep biological tissue at ultrasonic
resolution. In the last two decades, PAI evolved as a multi-scale imaging technology, enabling in vivo imaging from organelles to organs, and translated to several clinical applications such as breast and thyroid imaging. Nevertheless, the development of PAI systems for internal organs (e.g., prostate and ovaries) in the clinic has its challenges. In the first part of my talk, I will present the development of a transrectal ultrasound and photoacoustic (TRUSPA) human prostate imaging system, and its validation in various phantoms, surgically removed human prostates, in vivo mouse models of prostate cancer, all the way to the first-in-human multispectral photoacoustic human prostate imaging results. In the second part of my talk, I will introduce some new research developments in my lab. This includes results from a multimodal thermoacoustic simulation platform, novel ultrasound transducers for high throughput and wearable
photoacoustic imaging, and low-cost portable photoacoustic imaging systems.

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Lecture / Discussion Mon, 28 Oct 2019 15:51:53 -0400 2019-10-31T09:00:00-04:00 2019-10-31T10:00:00-04:00 Chrysler Center Biomedical Engineering Lecture / Discussion BME Logo
International Economics (October 31, 2019 11:30am) https://events.umich.edu/event/68608 68608-17105368@events.umich.edu Event Begins: Thursday, October 31, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:38:38 -0400 2019-10-31T11:30:00-04:00 2019-10-31T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Law and Economics (October 31, 2019 4:30pm) https://events.umich.edu/event/68323 68323-17046000@events.umich.edu Event Begins: Thursday, October 31, 2019 4:30pm
Location: Jeffries Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 15:20:14 -0400 2019-10-31T16:30:00-04:00 2019-10-31T18:30:00-04:00 Jeffries Hall Department of Economics Workshop / Seminar economics
Applied Microeconomics/IO Seminar: Time-Varying Risk Aversion? Evidence from Near-Miss Accidents (November 1, 2019 10:00am) https://events.umich.edu/event/68382 68382-17071652@events.umich.edu Event Begins: Friday, November 1, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract

We present evidence consistent with time-varying risk preferences among automobile drivers. Exploiting a unique dataset of agents’ high-frequency driving behavior collected by a mobile phone application, we show that driving behavior changes after driving mishaps. Following “near-miss” accidents (measured by hard brakes or hard turns), drivers drive more conservatively, which is consistent with increased risk aversion following such mishaps. In a preferred specification, a near-miss triggers a reduction in driving distance of 8.12 kilometers, in-car cellphone use by 88.80%, and highway use by 34.88%. Calibration results indicate that such changes in behavior are consistent with an increase in risk aversion of [???]% and a reduction in annual insurance cost amounting to about 0.05–1.54% of the average car insurance premium.

Paper joint with Yi Xin, Caltech

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Workshop / Seminar Tue, 29 Oct 2019 16:20:15 -0400 2019-11-01T10:00:00-04:00 2019-11-01T11:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Heping Zhang, Susan Dwight Bliss Professor of Biostatistics, Professor in the Child Study Center and Professor of Statistics and Data Science, Yale University (November 1, 2019 10:00am) https://events.umich.edu/event/63887 63887-15977789@events.umich.edu Event Begins: Friday, November 1, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Ordinal outcomes are common in scientific research and everyday practice, and we often rely on regression models to make inference. A long-standing problem with such regression analyses is the lack of effective diagnostic tools for validating model assumptions. The difficulty arises from the fact that an ordinal variable has discrete values that are labeled with, but not, numerical values. The values merely represent ordered categories. In this paper, we propose a surrogate approach to defining residuals for an ordinal outcome Y. The idea is to define a continuous variable S as a ``surrogate'' of Y and then obtain residuals based on S. For the general class of cumulative link regression models, we study the residual's theoretical and graphical properties. We show that the residual has null properties similar to those of the common residuals for continuous outcomes. Our numerical studies demonstrate that the residual has power to detect misspecification with respect to 1) mean structures; 2) link functions; 3) heteroscedasticity; 4) proportionality; and 5) mixed populations. The proposed residual also enables us to develop numeric measures for goodness-of-fit using classical distance notions. Our results suggest that compared to a previously defined residual, our residual can reveal deeper insights into model diagnostics. We stress that this work focuses on residual analysis, rather than hypothesis testing. The latter has limited utility as it only provides a single p-value, whereas our residual can reveal what components of the model are misspecified and advise how to make improvements.

This is a joint work with Dungang Liu, University of Cincinnati Lindner College of Business.

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Workshop / Seminar Wed, 23 Oct 2019 12:43:56 -0400 2019-11-01T10:00:00-04:00 2019-11-01T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Heping Zhang
ISD Manufacturing Seminar Series (November 1, 2019 10:30am) https://events.umich.edu/event/68798 68798-17153401@events.umich.edu Event Begins: Friday, November 1, 2019 10:30am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, November 8, 2019 from 11:00am-12:00pm in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Manufacturing Seminar Series Speaker, with Xun Huan, Ph.D. Professor Huan is an Assistant Professor of Mechanical Engineering at the University of Michigan.

In this presentation, Dr. Huan will talk about finding the most useful data and how using a careful design of limited data acquisition opportunities can lead to substantial resource savings.
RSVP here: https://forms.gle/b94JCeg23jJwu3Li9

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Workshop / Seminar Tue, 05 Nov 2019 12:25:41 -0500 2019-11-01T10:30:00-04:00 2019-11-01T11:30:00-04:00 Chrysler Center Integrative Systems + Design Workshop / Seminar MFG Seminar
MCDB Seminar: UTI Pathogenesis, Host-Pathogen Interface, Antibiotic-sparing therapeutics (November 1, 2019 12:00pm) https://events.umich.edu/event/67348 67348-16839904@events.umich.edu Event Begins: Friday, November 1, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Matt Chapman

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Workshop / Seminar Tue, 17 Sep 2019 15:23:11 -0400 2019-11-01T12:00:00-04:00 2019-11-01T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar high resolution micrograph of pathogenic bacteria binding to tissue
Economics at Work (November 1, 2019 1:00pm) https://events.umich.edu/event/68594 68594-17105353@events.umich.edu Event Begins: Friday, November 1, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Rachel is currently the Head of Business Development at One Rockwell, a full-service ecommerce agency.
Her career is powered by a passion for helping brands grow their business, and in a belief that an exceptional brand story and the right technology are the foundational elements to sustained success. At One Rockwell she leads a team to generate leads, expand agency verticals, and collaborate with product to constantly evolve their offerings. Previously, over three years at Lyst, she co-led US partnerships generating industry buy-in for their proprietary technology and helping the site to amass over 2.5 million live products in their largest market.
Strengths include creative problem solving, industry alignment, a deep understanding of the ecommerce ecosystem, and creating a superior retail experience. Rachel has worked with brands including Dior, COTY, Vera Bradley, Schiaparelli Haute Couture, Farm Rio, American Eagle/aerie, and more. She carries an Economics degree from the University of Michigan and is on the Board of Advisors for the Michigan Fashion Media Summit (MFMS).


Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Mon, 28 Oct 2019 09:10:18 -0400 2019-11-01T13:00:00-04:00 2019-11-01T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory (November 1, 2019 2:30pm) https://events.umich.edu/event/68619 68619-17105385@events.umich.edu Event Begins: Friday, November 1, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 14:17:30 -0400 2019-11-01T14:30:00-04:00 2019-11-01T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar economics
Applied Microeconomics/IO & Public Finance Seminar: Targeting In-Kind Transfers Through Market Design: A Revealed Preference Analysis of Public Housing Allocation (November 4, 2019 10:00am) https://events.umich.edu/event/66770 66770-16776783@events.umich.edu Event Begins: Monday, November 4, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

Public housing benefits are rationed through waitlists. This paper argues that the range of allocation policies used across U.S. cities involves a trade-off between two policy objectives: maximizing welfare gains for tenants, and targeting the most economically disadvantaged applicants. Using waitlist data from Cambridge, MA, I develop and estimate a model of public housing preferences in a setting where heterogeneous apartments are rationed through waiting time. Counterfactual simulations show that the preferred mechanism depends on social preferences for redistribution. However, many cities use systems that would be suboptimal in Cambridge for any value of redistribution.

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Workshop / Seminar Tue, 10 Sep 2019 10:12:55 -0400 2019-11-04T10:00:00-05:00 2019-11-04T11:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Complexity and shrouded attributes in incentive schemes: The case of the ratchet effect (November 4, 2019 11:45am) https://events.umich.edu/event/68614 68614-17105375@events.umich.edu Event Begins: Monday, November 4, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

This paper shows that the impact of workplace incentive schemes can depend on the complexity of the scheme, and also the cognitive ability of the worker population, because these matter for whether certain features of the scheme are shrouded attributes. Specifically, the findings indicate that complexity and bounded rationality can cause workers to overlook a dynamic aspect of workplace incentive contracts that would otherwise create perverse incentives to reduce effort, the so-called ratchet effect. The findings are based on a combination of large-scale, long-term field experiments within a warehouse, online experiments conducted with the same worker population, and online experiments conducted with workers on Amazon Mechanical Turk. The field experiments find only a weak ratchet effect. The online experiments build the case that for many workers, particularly those with lower cognitive ability, ratchet effects may be weak because in the relatively complex scheme, the dynamic aspect of incentives is a shrouded attribute. Making the scheme simpler causes the ratchet effect to emerge. The evidence suggests that there may be an optimal degree of complexity that allows firms to harness static incentives while avoiding perverse dynamic incentives. A systematic analysis of what types of changes to the contract make the ratchet effect stronger or weaker provides findings with implications for incentive design as well as shedding light on the nature of complexity in general.

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Workshop / Seminar Fri, 18 Oct 2019 13:15:37 -0400 2019-11-04T11:45:00-05:00 2019-11-04T12:45:00-05:00 North Quad Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Michael Krautmann, MSE (November 4, 2019 4:30pm) https://events.umich.edu/event/68998 68998-17211731@events.umich.edu Event Begins: Monday, November 4, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Proven medicines and technologies already exist to address many of the world's biggest health challenges. But these products are only effective when they can be reliably delivered to the patients who need them, and in many low- and middle-income countries (LMICs), health product supply chains are not as efficient or reliable as they need to be. Patients and providers often lack access to quality, affordable medicines, and health outcomes suffer as a result.
 
Governments, businesses, multilateral agencies, and nonprofits are all play a critical role in LMIC health supply chains, but each have their own unique perspectives, processes, and goals. Improving supply chain performance in this context requires a systems thinking approach, one that combines traditional logistics management and optimization techniques with a more holistic understanding of how to incentivize and align the actions of diverse organizations.
 
In this session we will explore the William Davidson Institute's work in improving LMIC health supply chain performance, and will highlight lessons and experiences that are applicable in any complex health system environment.

Michael Krautmann joined the William Davidson Institute's Healthcare Initiative in 2015. His research and consulting work focuses on modeling, investment decisionmaking, and strategy development to improve the operational efficiency and service levels of public health supply chains. While at WDI Michael has helped develop several Excel tools and white papers that inform key elements of the supply chain design and strategy development process. He has also conducted strategic evaluations of ongoing supply chain programs in several countries, helping client organizations improve their approach for providing technical assistance and delivering health products.
 
Michael holds master’s and bachelor’s degrees in Industrial and Operations Engineering from the University of Michigan.  Prior to joining WDI, he worked for Lean Care Solutions, a healthcare technology startup that uses predictive analytics to help hospitals improve patient scheduling and postoperative care. He also served as a Peace Corps Volunteer in Zambia, where he helped evaluate clinic-level supply chain practices for a United States Agency for International Development-funded health project.

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Lecture / Discussion Thu, 31 Oct 2019 09:26:56 -0400 2019-11-04T16:30:00-05:00 2019-11-04T18:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Michael Krautmann, MSE
Health, History, Demography & Development (H2D2) (November 5, 2019 11:30am) https://events.umich.edu/event/68832 68832-17161712@events.umich.edu Event Begins: Tuesday, November 5, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 25 Oct 2019 10:19:09 -0400 2019-11-05T11:30:00-05:00 2019-11-05T12:50:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Mechanisms of Ribosome-Associated Quality Control- Biological Chemistry Seminar (November 5, 2019 12:00pm) https://events.umich.edu/event/68247 68247-17035290@events.umich.edu Event Begins: Tuesday, November 5, 2019 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Sichen Shao, Assistant Professor of Cell Biology at Harvard Medical School, will deliver the weekly Department of Biological Chemistry Seminar on Tuesday November 5th, 2019. Please join us in North Lecture Hall, MS II for this seminar.

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Lecture / Discussion Thu, 10 Oct 2019 07:46:26 -0400 2019-11-05T12:00:00-05:00 2019-11-05T13:00:00-05:00 Medical Science Unit II Biological Chemistry Lecture / Discussion Sichen Shao
Labor Economics & Economic History: Can you move to opportunity? Evidence from the Great Migration (November 5, 2019 2:30pm) https://events.umich.edu/event/68314 68314-17045992@events.umich.edu Event Begins: Tuesday, November 5, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

The northern United States long served as a land of opportunity for black Americans, but today the region's racial gap in intergenerational mobility rivals that of the South. I show that racial composition changes during the peak of the Great Migration (1940-1970) reduced upward mobility in northern cities in the long run, with the largest effects on black men. I identify urban black population increases during the Migration at the commuting zone level using a shift-share instrument, interacting pre-1940 black southern migration patterns with predicted out-migration from southern counties. The Migration's negative effects on children's adult outcomes appear driven by neighborhood factors, not changes in the characteristics of the average child. As early as the 1960s, the Migration led to greater white enrollment in private schools, increased spending on policing, and higher crime and incarceration rates. I estimate that the overall change in childhood environment induced by the Great Migration explains 28% of the upward mobility gap between black and white households in the region today.

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Workshop / Seminar Mon, 28 Oct 2019 09:11:17 -0400 2019-11-05T14:30:00-05:00 2019-11-05T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Department of Computational Medicine & Bioinformatics Weekly Seminar (November 6, 2019 4:00pm) https://events.umich.edu/event/68926 68926-17197024@events.umich.edu Event Begins: Wednesday, November 6, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract: Although central architectures drive robust oscillations, biological clock networks containing the same core vary drastically in their potential to oscillate. What peripheral structures contribute to the variation of oscillation behaviors remains elusive. We computationally generated an atlas of oscillators and found that, while certain core topologies are essential for robust oscillations, local structures substantially modulate the degree of robustness. Strikingly, two key local structures, incoherent inputs and coherent inputs, can modify a core topology to promote and attenuate its robustness, additively. These findings underscore the importance of local modifications besides robust cores, which explain why auxiliary structures not required for oscillation are evolutionarily conserved. We further apply this computational framework to search for structures underlying tunability, another crucial property shared by many biological timing systems to adapt their frequencies to environmental changes.

Experimentally, we developed an artificial cell system to reconstitute mitotic oscillatory processes in water-in-oil microemulsions. With a multi-inlet pressure-driven microfluidic setup, these artificial cells are flexibly adjustable in sizes, periods, various molecular and drug concentrations, energy, and subcellular compartments. Using long-term time-lapse fluorescence microscopy, this system enables high-throughput, single-cell analysis of clock dynamics, functions, and stochasticity, key to elucidating the topology-function relation of biological clocks.

We also investigate how multiple clocks coordinate via biochemical and mechanical signals in the essential developmental processes of early zebrafish embryos (e.g., mitotic wave propagation, synchronous embryo cleavages, and somitogenesis). To pin down the physical mechanisms that give rise to these complex collective phenomena, we integrate mathematical modeling, live embryo and explant imaging, nanofabrication, micro-contact printing, and systems and synthetic biology approaches.

BlueJeans livestream: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc
Qiong Yang: https://medicine.umich.edu/dept/dcmb/qiong-yang-phd

3:45 pm to 4:00 pm - Light refreshments
4:00 pm - Lecture

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Lecture / Discussion Tue, 29 Oct 2019 12:56:42 -0400 2019-11-06T16:00:00-05:00 2019-11-06T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Macroeconomics (November 6, 2019 4:00pm) https://events.umich.edu/event/68257 68257-17037411@events.umich.edu Event Begins: Wednesday, November 6, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Thu, 10 Oct 2019 13:03:09 -0400 2019-11-06T16:00:00-05:00 2019-11-06T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
International Economics (November 7, 2019 11:30am) https://events.umich.edu/event/68609 68609-17105369@events.umich.edu Event Begins: Thursday, November 7, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:35:21 -0400 2019-11-07T11:30:00-05:00 2019-11-07T13:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Law and Economics (November 7, 2019 4:30pm) https://events.umich.edu/event/68324 68324-17046001@events.umich.edu Event Begins: Thursday, November 7, 2019 4:30pm
Location: Jeffries Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 15:21:55 -0400 2019-11-07T16:30:00-05:00 2019-11-07T18:30:00-05:00 Jeffries Hall Department of Economics Workshop / Seminar economics
ISD Design Science Seminar (November 8, 2019 9:30am) https://events.umich.edu/event/69144 69144-17252909@events.umich.edu Event Begins: Friday, November 8, 2019 9:30am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, November 8, 2019 from 9:30-11:00 am in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Design Science Seminar Series with speaker Malcolm McCullough, Ph.D. Dr. McCullough is a Professor of Architecture, Taubman Architecture and Urban Planning at the University of Michigan. He is the author of the books Downtime on the Microgrid (forthcoming 2020), Ambient Commons (2013), Digital Ground (2005), and Abstracting Craft (1997) all with the MIT Press.

Whereas “the smart city” has most often been understood as a totality, top-down and always-on, in today’s climate-altered reality more agendas instead need to advance a more locally clustered, adaptive resilience. Otherwise, the most salient aspect of any future smart city is its fragility. While not a report on complexity simulations, this talk reexamines some perhaps-familiar principles of adaptive clustering from three less conventional perspectives.

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Workshop / Seminar Tue, 05 Nov 2019 14:37:09 -0500 2019-11-08T09:30:00-05:00 2019-11-08T11:00:00-05:00 Chrysler Center Integrative Systems + Design Workshop / Seminar DESCI Seminar
ROOM CHANGE: Statistics Department Seminar Series: Matthew Stephens, Professor, Departments of Statistics and Human Genetics, University of Chicago (November 8, 2019 10:00am) https://events.umich.edu/event/63888 63888-15977790@events.umich.edu Event Begins: Friday, November 8, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Ever since the pioneering work of James and Stein, the normal means model has been the canonical model for illustrating the ideas and benefits of shrinkage estimation, and has been the subject of considerable theoretical study. By comparison, practical applications of the normal means model are relatively rare, and it has generally been overshadowed by methods like L1-regularization as a way of inducing sparsity. Here we argue that this should change: we describe some recently-developed Empirical Bayes ways to solve the normal means model, and describe how they can be applied to induce shrinkage, sparsity and smoothness in a range of practical applications, including False Discovery Rates, non-parametric regression, sparse regression, and sparse principal components analysis or factor analysis.

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Workshop / Seminar Mon, 04 Nov 2019 09:59:05 -0500 2019-11-08T10:00:00-05:00 2019-11-08T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Matthew Stephens
ISD Manufacturing Seminar Series (November 8, 2019 11:00am) https://events.umich.edu/event/68798 68798-17252891@events.umich.edu Event Begins: Friday, November 8, 2019 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, November 8, 2019 from 11:00am-12:00pm in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Manufacturing Seminar Series Speaker, with Xun Huan, Ph.D. Professor Huan is an Assistant Professor of Mechanical Engineering at the University of Michigan.

In this presentation, Dr. Huan will talk about finding the most useful data and how using a careful design of limited data acquisition opportunities can lead to substantial resource savings.
RSVP here: https://forms.gle/b94JCeg23jJwu3Li9

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Workshop / Seminar Tue, 05 Nov 2019 12:25:41 -0500 2019-11-08T11:00:00-05:00 2019-11-08T12:00:00-05:00 Chrysler Center Integrative Systems + Design Workshop / Seminar MFG Seminar
MCDB Seminar: Cellular Pathways Regulating Early Pollen-Pistil Interactions and Self-Fertility (November 8, 2019 12:00pm) https://events.umich.edu/event/67360 67360-16839926@events.umich.edu Event Begins: Friday, November 8, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Cora MacAlister

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Workshop / Seminar Tue, 17 Sep 2019 16:38:38 -0400 2019-11-08T12:00:00-05:00 2019-11-08T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar close up photo of flower with parts labelled
Economics at Work (November 8, 2019 1:00pm) https://events.umich.edu/event/68597 68597-17105355@events.umich.edu Event Begins: Friday, November 8, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Fri, 18 Oct 2019 12:20:41 -0400 2019-11-08T13:00:00-05:00 2019-11-08T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory: Bargaining with Persistent Private Information (November 8, 2019 2:30pm) https://events.umich.edu/event/69030 69030-17220011@events.umich.edu Event Begins: Friday, November 8, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

I study a bargaining game in which a seller makes offers to a buyer. The buyer is privately informed about her valuation, and the seller privately observes her stochastically changing production cost. The seller's time-varying private information gives rise to new dynamics. Prices fall gradually at the early stages of negotiations, and trade is inefficiently delayed. Inefficiencies persist even when gains from trade are common knowledge. Privately observed costs lead to lower welfare, higher seller revenue and lower buyer surplus (especially for high-value buyers) relative to a setting with publicly-observed costs.

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Workshop / Seminar Wed, 06 Nov 2019 09:38:01 -0500 2019-11-08T14:30:00-05:00 2019-11-08T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
UMMA Pop Up: Warren & Flick (November 9, 2019 1:00pm) https://events.umich.edu/event/68741 68741-17147129@events.umich.edu Event Begins: Saturday, November 9, 2019 1:00pm
Location: Museum of Art
Organized By: University of Michigan Museum of Art (UMMA)

Warren & Flick explore the nuanced textures of a two person ensemble. Using both original material and arranged standards from many genres, this ensemble finds new depth in the simplicity of a duo. Jacob Warren plays double bass, while Grant Flick plays violin, tenor guitar and nyckelharpa. Currently based out of Ann Arbor, Michigan, the two met at the 2015 Acoustic Music Seminar (AMS), a program accepting only sixteen young string players from around the world to participate in a week of intense, improvisation, composition and performance training. They released their debut album "Kestrel" in September 2019.

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Other Sat, 09 Nov 2019 18:16:57 -0500 2019-11-09T13:00:00-05:00 2019-11-09T14:00:00-05:00 Museum of Art University of Michigan Museum of Art (UMMA) Other Museum of Art
Public Finance (November 11, 2019 4:00pm) https://events.umich.edu/event/67503 67503-16866609@events.umich.edu Event Begins: Monday, November 11, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come

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Workshop / Seminar Fri, 20 Sep 2019 17:11:03 -0400 2019-11-11T16:00:00-05:00 2019-11-11T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Lavanya Marla, PhD (November 11, 2019 4:30pm) https://events.umich.edu/event/69237 69237-17269241@events.umich.edu Event Begins: Monday, November 11, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

We present an efficient data-driven computational solution and bounding approach for static allocation of an ambulance fleet and its dynamic redeployment, where the goal is to position (or re-position) ambulances to bases to maximize the system's service level. Central to our approach is a discrete-event simulator to evaluate the impact of ambulance deployments to logs of emergency requests. We first model ambulance allocation as an approximately-submodular-maximization problem, and devise a simple and efficient greedy algorithm that produces both static allocations and dynamic repositioning policies. In parallel, we find data-driven information-relaxation bounds for both static and dynamic cases. We build even tighter information-relaxation bounds by penalizing the previous relaxations. Our approach allows the computation of tight bounds without incurring the curse of dimensionality common to such approaches. Our bounding methods help inform policymakers about the viability of proposed fleet sizes and policies being adopted by the contracted EMS agencies. Our computational experiments on an Asian city's EMS demonstrate the tractability and efficiency of our greedy algorithm and our bounding methods.

The first part of this work is with Ramayya Krishnan and Yisong Yue, and the latter part with Achal Bassamboo.

Lavanya Marla is an Assistant Professor in Industrial and Enterprise Systems Engineering at the University of Illinois at Urbana-Champaign. Prior to her current position, she was a Systems Scientist with the Heinz College at Carnegie Mellon University; and earned her PhD in Transportation Systems from MIT and Bachelors degree from IIT Madras. Her research interests are in robust and dynamic decision-making under uncertainty and game theoretic analysis for large-scale transportation and logistics systems; combining tools from data-driven optimization, statistics, simulation and machine learning. Her research is funded by an integrative National Science Foundation grant, a Department of Homeland Security cyber-security grant, the Department of Transportation, the US-India Educational Foundation, the INFORMS Transportation and Logistics Society and aviation companies. Her work has received an Honorable mention for the Anna Valicek award from AGIFORS, a best presentation award from AGIFORS, a KDD Startup Research award, and a Top-10 cited paper recognition from Transportation Research – Part A.

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: https://bme.umich.edu/about/maps-directions/.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 07 Nov 2019 15:23:33 -0500 2019-11-11T16:30:00-05:00 2019-11-11T18:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Lavanya Marla, PhD
Health, History, Demography & Development (H2D2) (November 12, 2019 11:30am) https://events.umich.edu/event/68833 68833-17161713@events.umich.edu Event Begins: Tuesday, November 12, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 25 Oct 2019 10:20:58 -0400 2019-11-12T11:30:00-05:00 2019-11-12T12:50:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic History: Freeway Revolts! The Quality of Life Effects of Highways (November 12, 2019 2:30pm) https://events.umich.edu/event/68315 68315-17045993@events.umich.edu Event Begins: Tuesday, November 12, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

Why do freeways affect the spatial organization of the economy? We identify freeway disameni-ties in urban areas and quantify their effects. First, freeways had negative effects on central neighborhoods but positive effects on suburban neighborhoods. These diverging patterns iden-tify freeway disamenities in a theory where disamenities outweigh minimal access benefits near downtown, but superior access benefits outweigh disamenities on the periphery. Second, in a quantitative spatial general equilibrium model, the welfare costs of freeway disamenities are large, and one-third of the causal effect of freeways on central-city decline can be attributed to quality of life effects. Third, barrier effects are significant and a major factor in the dis-amenity value of living near a freeway. Disamenities from freeways, as opposed to their regional accessibility benefits, had large effects on the spatial structure of cities, suburbanization, and welfare.

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Workshop / Seminar Fri, 25 Oct 2019 13:14:08 -0400 2019-11-12T14:30:00-05:00 2019-11-12T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
MIPSE Seminar | Substorms, Dipolarization, and Particle Acceleration in the Magnetosphere (November 13, 2019 3:30pm) https://events.umich.edu/event/65976 65976-16678379@events.umich.edu Event Begins: Wednesday, November 13, 2019 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Magnetosphere plasma dynamics continue to challenge our understanding of energy release in the near-earth environment. Magneto-hydrodynamics (MHD), particle-in-Cell (PIC), and test particle simulations are used to describe the dynamic evolution of the magnetotail, associated with substorms (energy releases from the magnetotail) and other dipolarization events. Simulations show the formation of thin current sheets embedded in the wider plasma sheet due to solar wind interactions. PIC then demonstrates the onset of tearing instabilities and magnetic reconnection, causing fast plasma flows and dipolarization. These phenomena are then followed by MHD simulations which form the basis of test particle simulations, which pro-vide details on acceleration mechanisms, and phase space distributions. Results compare favorably with THEMIS and MMS observations.

About the Speaker:
Joachim Birn received his PhD. in 1973 at the Technical Univ. Berlin studying the Stability of the Planetary System. From 1973-82 he was at Ruhr-University Bochum working on equilibrium modeling and magnetohydrodynamic (MHD) simulations of the Earth’s magnetotail. In 1980 he was a visitor at Los Alamos National Lab. (LANL), where he extended his 2D MHD code to 3D, simulating substorm dynamics of the magnetotail. From 1982 to 2012 he was at LANL continuing his simulation work, working on satellite data interpretation and studying acceleration of ions and electrons in magnetospheric substorms. Since 2012 he is a Senior Research Scientist at the Space Science Institute in Boulder. Birn’s research experience includes 3D equilibrium theory, development of 3D MHD codes with applications to magnetotail and solar corona dynamics; and MHD stability theory on which he has published 260 refereed papers. Birn is a Fellow of the American Geophysical Union and LANL Fellow.

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Lecture / Discussion Thu, 29 Aug 2019 12:35:07 -0400 2019-11-13T15:30:00-05:00 2019-11-13T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Joachim Birn
Department of Computational Medicine & Bioinformatics Seminar (November 13, 2019 4:00pm) https://events.umich.edu/event/68641 68641-17128443@events.umich.edu Event Begins: Wednesday, November 13, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk Title: Reproducibility with high-dimensional data

Abstract: With the expanding generation of large-scale biological datasets, there has been an ever-greater concern in understanding the reproducibility of discoveries and findings in a statistically reliable manner. We review several concepts in reproducibility and describe how one can adopt a multiple testing perspective on the problem. This leads to an intuitive procedure for assessing reproducibility. We demonstrate application of the methodology using RNA-sequencing data as well as metabolomics datasets. We will also outline some further problems in the field.

This is joint work with Daisy Philtron, Yafei Lyu and Qunhua Li (Penn State) and Tusharkanti Ghosh, Weiming Zhang and Katerina Kechris (University of Colorado).

DCMB Faculty Host: Alla Karnovsky, PhD

3:45 p.m. - Light Refreshments
4:00 p.m. - Lecture

BlueJeans Live Streaming: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc

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Lecture / Discussion Mon, 21 Oct 2019 11:05:22 -0400 2019-11-13T16:00:00-05:00 2019-11-13T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Macroeconomics (November 13, 2019 4:00pm) https://events.umich.edu/event/68259 68259-17037413@events.umich.edu Event Begins: Wednesday, November 13, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Thu, 10 Oct 2019 13:05:58 -0400 2019-11-13T16:00:00-05:00 2019-11-13T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
BME 500 Seminar: Stephanie Seidelits (November 14, 2019 9:00am) https://events.umich.edu/event/69387 69387-17316493@events.umich.edu Event Begins: Thursday, November 14, 2019 9:00am
Location: Chrysler Center
Organized By: Biomedical Engineering

Stephanie Seidelits, University of California Los Angeles
Details TBD

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Workshop / Seminar Wed, 13 Nov 2019 09:34:12 -0500 2019-11-14T09:00:00-05:00 2019-11-14T10:00:00-05:00 Chrysler Center Biomedical Engineering Workshop / Seminar BME Event
International Economics (November 14, 2019 11:30am) https://events.umich.edu/event/68610 68610-17105370@events.umich.edu Event Begins: Thursday, November 14, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:37:25 -0400 2019-11-14T11:30:00-05:00 2019-11-14T13:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Ben Hansen, Associate Professor, Department of Statistics, University of Michigan (November 15, 2019 10:00am) https://events.umich.edu/event/63889 63889-15977791@events.umich.edu Event Begins: Friday, November 15, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

To estimate intervention effects without the benefit of random assignment, an often useful beginning is to pair intervention group members to ostensibly similar counterparts receiving a control condition. In practice exact matches are rare, particularly if there are many measured covariates. Instead, matches may be made within calipers (Althauser & Rubin, 1970) of a unidimensional index. Modern indices arise by modeling specific aspects of the data. The most widely used matching indices are propensity scores (Rosenbaum & Rubin, 1983), followed by risk or prognostic scores (Miettinen, 1976; Hansen, 2008).

Adjudicating how close is close enough for matching is the murkiest aspect of the undertaking. Heuristics in wide use today pre-date the use of model-based matching indices, fail to adapt to the size of the model and sample, and lack theoretical support. In some cases these heuristics allow pairings of demonstrably dissimilar subjects; in others they declare wide swaths of the sample to be unmatchable, needlessly wasting data.

This talk presents a new way to determine calipers. Compatible with common index model specifications, its widths diminish as n increases, toward an asymptote of 0. If the index model is consistently estimated, then matched contrast-based impact estimates will be consistent as well, provided matches are made within these diminishing calipers. This result assumes no hidden bias, an untestable condition, alongside of additional conditions that can be enforced. In particular, it restricts growth of the index parameter's dimension relative to n, to a rate intermediate to those required for ordinary M-estimates to be consistent or root-n consistent (He & Shao, 2000).

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Workshop / Seminar Fri, 08 Nov 2019 14:37:06 -0500 2019-11-15T10:00:00-05:00 2019-11-15T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Hansen,Ben
MCDB Seminar: Maps and Neural Codes in Whisker Somatosensory Cortex (November 15, 2019 12:00pm) https://events.umich.edu/event/67361 67361-16839927@events.umich.edu Event Begins: Friday, November 15, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Sam Kwon

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Workshop / Seminar Tue, 17 Sep 2019 16:45:08 -0400 2019-11-15T12:00:00-05:00 2019-11-15T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar collage: rat whisker, micrograph, signals
Economics at Work (November 15, 2019 1:00pm) https://events.umich.edu/event/68599 68599-17105356@events.umich.edu Event Begins: Friday, November 15, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Fri, 18 Oct 2019 12:22:32 -0400 2019-11-15T13:00:00-05:00 2019-11-15T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Labor Economics (November 15, 2019 1:00pm) https://events.umich.edu/event/68422 68422-17080055@events.umich.edu Event Begins: Friday, November 15, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 15 Oct 2019 15:16:17 -0400 2019-11-15T13:00:00-05:00 2019-11-15T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Using micro-randomized trials to study processes underlying response to mobile health interventions (November 18, 2019 11:45am) https://events.umich.edu/event/68615 68615-17105376@events.umich.edu Event Begins: Monday, November 18, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

Micro-randomized trials (MRTs) are a new experimental design for optimizing just-in-time adaptive interventions. In addition to informing intervention design, however, MRTs can also provide insights into the underlying psychosocial processes that mediate intervention response. In this talk, I will describe some of the recent findings from the HeartSteps project which show that mHealth interventions provided in the exact same way (in our case, as push notifications suggesting to individuals how they can be active in their current context) can have different dynamics, suggesting that the response to them is mediated by different underlying processes. I suggest that, in addition to supporting intervention design, MRTs can be a powerful tool for studying human behavior in a granular way in the midst of messiness of day-to-day life.

Bio

Predrag "Pedja" Klasnja is an Assistant Professor in the School of Information at the University of Michigan. He works at the intersection of human-computer interaction and behavioral science, and he studies how mobile technologies can help individuals make and sustain health-protective lifestyle changes. He is particularly interested in the design and evaluation of just-in-time adaptive interventions, technologies that continuously adapt their functioning to provide optimal support to individuals as their needs and circumstances change.

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Workshop / Seminar Mon, 11 Nov 2019 14:31:01 -0500 2019-11-18T11:45:00-05:00 2019-11-18T12:45:00-05:00 North Quad Department of Economics Workshop / Seminar economics
Cognitive Science Seminar Series (November 18, 2019 3:00pm) https://events.umich.edu/event/67489 67489-16864388@events.umich.edu Event Begins: Monday, November 18, 2019 3:00pm
Location: Weiser Hall
Organized By: Weinberg Institute for Cognitive Science

Graduate student Stella Hao (Cognition and Cognitive Neuroscience) will give a talk on "Bounded Rationality of Moral Cognition."

ABSTRACT

My work investigates moral cognition (i.e., moral decisions, moral judgments, and moral inferences, Yu, Siegel, \& Crockett, 2011) in the framework of bounded rationality. Moral cognition is not only a reflection of personal values and a gateway for explaining human behaviors, but also a field of work that provides insights relevant to the dynamics of human society and the development of artificial intelligence. Thus, it is extremely important to bridge the gap between morality and human rationality while taking into account the ecology of the environment and the agent. Bounded rationality provides a way to approach decision making research by taking into account how rationality is constrained by the characteristics of the environment and the cognitive limitation of the mind. In this talk, I will provide an overview of the current research on bounded moral cognition and present some empirical results of finding context effects in ethical decision making. Finally, I will present some research goals of my dissertation work.

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Lecture / Discussion Fri, 15 Nov 2019 10:25:02 -0500 2019-11-18T15:00:00-05:00 2019-11-18T16:30:00-05:00 Weiser Hall Weinberg Institute for Cognitive Science Lecture / Discussion Weiser Hall
Public Finance: Audits as Evidence: Experiments, Ensembles, and Enforcement (November 18, 2019 4:00pm) https://events.umich.edu/event/67504 67504-16866610@events.umich.edu Event Begins: Monday, November 18, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

We develop tools for utilizing correspondence experiments to detect illegal discrimination by individual employers. Employers violate US employment law if their propensity to contact applicants depends on protected characteristics such as race or sex. We establish identification of higher moments of the causal effects of protected characteristics on callback rates as a function of the number of fictitious applications sent to each job ad. These moments are used to bound the fraction of jobs that illegally discriminate. Applying our results to three experimental datasets, we find evidence of significant employer heterogeneity in discriminatory behavior, with the standard deviation of gaps in job-specific callback probabilities across protected groups averaging roughly twice the mean gap. In a recent experiment manipulating racially distinctive names, we estimate that at least 85% of jobs that contact both of two white applications and neither of two black applications are engaged in illegal discrimination. To assess more carefully the tradeoff between type I and II errors presented by these behavioral patterns, we consider the performance of a series of decision rules for investigating suspicious callback behavior under a simple two-type model that rationalizes the experimental data. Though, in our preferred specification, only 17% of employers are estimated to discriminate on the basis of race, we find that an experiment sending 10 applications to each job would enable accurate detection of 7-10% of discriminators while falsely accusing fewer than 0.2% of non-discriminators. A minimax decision rule acknowledging partial identification of the joint distribution of callback rates yields higher error rates but more investigations than our baseline two-type model. Our results suggest illegal labor market discrimination can be reliably monitored with relatively small modifications to existing audit designs. (joint with Patrick Kline)

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Workshop / Seminar Thu, 31 Oct 2019 09:22:15 -0400 2019-11-18T16:00:00-05:00 2019-11-18T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Health, History, Demography & Development (H2D2) (November 19, 2019 11:30am) https://events.umich.edu/event/68835 68835-17161715@events.umich.edu Event Begins: Tuesday, November 19, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details come

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Workshop / Seminar Fri, 25 Oct 2019 10:24:46 -0400 2019-11-19T11:30:00-05:00 2019-11-19T12:50:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
How to Make RNA Polymerase Processive- Department of Biological Chemistry Seminar (November 19, 2019 12:00pm) https://events.umich.edu/event/68248 68248-17035291@events.umich.edu Event Begins: Tuesday, November 19, 2019 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Irina Artsimovitch, Professor of Microbiology at Ohio State University, will be delivering the weekly Department of Biological Chemistry Seminar on Tuesday 11/19/19 at 12 noon in North Lecture Hall, MS II.

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Lecture / Discussion Thu, 10 Oct 2019 07:54:20 -0400 2019-11-19T12:00:00-05:00 2019-11-19T13:00:00-05:00 Medical Science Unit II Biological Chemistry Lecture / Discussion Artsimovitch
Economic History: Marriage and the Intergenerational Mobility of Women: Evidence from Marriage Certificates 1850-1910 (November 19, 2019 2:30pm) https://events.umich.edu/event/69013 69013-17213805@events.umich.edu Event Begins: Tuesday, November 19, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

The literature finds a high degree of economic mobility for men in the 19th century in comparison to today. However, due to data limitations, changes in female economic mobility over time are not well understood. Using a set of marriage certificates from Massachusetts over the period of 1850-1910, we link men and women to their childhood and adult census records to obtain a measure of occupational standing across two generations. Intergenerational mobility for women is higher than for men during 1850-1880. Between 1880-1910, men’s mobility increases to converge with that of women. We also find evidence of assortative mating based on the correlation in occupational income score and real estate wealth between the husband’s and wife’s fathers.

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Workshop / Seminar Wed, 06 Nov 2019 12:33:10 -0500 2019-11-19T14:30:00-05:00 2019-11-19T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar Economics
DCMB Weekly Seminar (November 20, 2019 4:00pm) https://events.umich.edu/event/68972 68972-17205312@events.umich.edu Event Begins: Wednesday, November 20, 2019 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract: GWAS of neuropsychiatric diseases have identified many loci, however, causal variants often remain unknown. We performed ATAC-seq in human iPSC-derived neurons, and identified thousands of variants affecting chromatin accessibility. Such variants are highly enriched with risk variants of a range of brain disorders. We computationally fine-mapped causal variants and experimentally tested their activities using CRISPRi followed by single cell RNA-seq. Our work provides a framework for prioritizing noncoding disease variants.

The second part of my talk will be focused on genetics of N6-methyladenosine (m6A), a common form of mRNA modification. m6A plays an important role in regulating various aspects of mRNA metabolism in eukaryotes. However, little is known about how DNA sequence variations may affect the m6A modification and the role of m6A in common diseases. We mapped genetic variants associated with m6A levels in 60 Yoruba lymphoblast cell lines. By leveraging these variants, our analysis provides novel insights of mechanisms regulating m6A installation, and downstream effects of m6A on other molecular traits such as translation rate. Integrated analysis with GWAS data reveals m6A variation as an important mechanism linking genetic variations to complex diseases.

BlueJeans livestreaming link: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc

3:45 p.m. - Light Refreshments
4:00 p.m. - Lecture

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Lecture / Discussion Wed, 30 Oct 2019 12:51:34 -0400 2019-11-20T16:00:00-05:00 2019-11-20T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
International Economics, Macroeconomics (November 20, 2019 4:00pm) https://events.umich.edu/event/68260 68260-17037414@events.umich.edu Event Begins: Wednesday, November 20, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:40:33 -0400 2019-11-20T16:00:00-05:00 2019-11-20T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
BME 500 Seminar: Alexander Opitz (November 21, 2019 9:00am) https://events.umich.edu/event/69388 69388-17316494@events.umich.edu Event Begins: Thursday, November 21, 2019 9:00am
Location: Chrysler Center
Organized By: Biomedical Engineering

Alexander Opitz, University of Minnesota.
Details TBD

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Workshop / Seminar Wed, 13 Nov 2019 09:33:21 -0500 2019-11-21T09:00:00-05:00 2019-11-21T10:00:00-05:00 Chrysler Center Biomedical Engineering Workshop / Seminar BME Event
Law and Economics (November 21, 2019 4:30pm) https://events.umich.edu/event/68325 68325-17046002@events.umich.edu Event Begins: Thursday, November 21, 2019 4:30pm
Location: Jeffries Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 15:23:35 -0400 2019-11-21T16:30:00-05:00 2019-11-21T18:30:00-05:00 Jeffries Hall Department of Economics Workshop / Seminar economics
ISD Design Science Seminar (November 22, 2019 9:30am) https://events.umich.edu/event/69368 69368-17310322@events.umich.edu Event Begins: Friday, November 22, 2019 9:30am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, November 22, 2019 from 9:30-11:00 am in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Design Science Seminar Series with speaker Mario Štorga, Ph.D. Dr. Štorga is the Head of the Chair of Design and Product Development in the Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia. He has led research in numerous national and international research and development projects, serves on the editorial boards of five journals, and has published more than 100 journal and conference papers.
In his talk, a research framework for experimental studies of engineering teams (both face-to-face and virtual) will be presented.

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Lecture / Discussion Tue, 12 Nov 2019 16:56:34 -0500 2019-11-22T09:30:00-05:00 2019-11-22T11:00:00-05:00 Chrysler Center Integrative Systems + Design Lecture / Discussion DESCI Seminar
Applied Microeconomics/IO Seminar: Network Formation and Bargaining in Vertical Markets: The Case of Narrow Networks in Health Insurance (November 22, 2019 10:00am) https://events.umich.edu/event/68280 68280-17037507@events.umich.edu Event Begins: Friday, November 22, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract

“Network Adequacy Regulations” intend to help consumers by forcing “narrow-network” insurance plans to include more hospitals. But they can also give hospitals excessive bargaining leverage, leading to increased reimbursement rates and premiums. To study this, I develop and estimate a model of network formation and bargaining between hospitals and insurers. Crucially, my bargaining formulation allows insurers to threaten to replace an in-network hospital with an out-of-network one. Applied to a health insurance market in Massachusetts, my model predicts that regulations mandating large minimum network sizes can raise prices substantially. Also, surprisingly, network adequacy regulations can cause “broad-network” plans to downsize.

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Workshop / Seminar Thu, 14 Nov 2019 14:31:13 -0500 2019-11-22T10:00:00-05:00 2019-11-22T11:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Sebastien Roch, Professor, Department of Mathematics, University of Wisconsin-Madison (November 22, 2019 10:00am) https://events.umich.edu/event/63890 63890-15977792@events.umich.edu Event Begins: Friday, November 22, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

Phylogenomics, the estimation of species phylogenies from genome-scale datasets, is a common step in many biological studies. This estimation is complicated by the fact that genes can evolve under processes, including incomplete lineage sorting (ILS), gene duplication and loss (GDL) and horizontal gene transfer (HGT), that make their trees conflict with the species history. I will survey recent progress on some statistical questions that arise in this context. Specifically, the identifiability of standard probabilistic models of phylogenomic data will be discussed, as well as the large-sample properties of computationally efficient methods for species tree estimation.

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Workshop / Seminar Fri, 15 Nov 2019 10:57:30 -0500 2019-11-22T10:00:00-05:00 2019-11-22T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Roch
ISD Manufacturing Seminar Series (November 22, 2019 11:00am) https://events.umich.edu/event/69420 69420-17318586@events.umich.edu Event Begins: Friday, November 22, 2019 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, November 22, 2019 from 11:00am-12:00pm in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Manufacturing Seminar Series Speaker, with Zhimin Xi , Ph.D. Professor Xi is an Assistant Professor in the Department of Industrial and Systems Engineering at the Rutgers University – New Brunswick. His research interests include reliability and safety for lithium-ion batteries, design for reliable engineering systems, model validation under uncertainty, and prognostics and health management for engineering systems.

This talk presents the integration of FE and data-driven modeling with systematic calibration and validation framework for the SLM process based on limited experiment data.

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Lecture / Discussion Wed, 13 Nov 2019 15:47:15 -0500 2019-11-22T11:00:00-05:00 2019-11-22T12:00:00-05:00 Chrysler Center Integrative Systems + Design Lecture / Discussion MFG Seminar
MCDB: Probing Golgi Apparatus Organization a Rab at a Time (November 22, 2019 12:00pm) https://events.umich.edu/event/67362 67362-16839928@events.umich.edu Event Begins: Friday, November 22, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Yanzhuang Wang

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Workshop / Seminar Mon, 11 Nov 2019 15:31:00 -0500 2019-11-22T12:00:00-05:00 2019-11-22T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar micrograph of golgi apparatus
Labor Economics: Revealing Stereotypes: Evidence from Immigrants in Schools (November 22, 2019 1:00pm) https://events.umich.edu/event/68423 68423-17080056@events.umich.edu Event Begins: Friday, November 22, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

We investigate whether individuals who are made aware of their stereotypes change their behavior, studying teacher bias in Italian schools. Teachers give lower grades to immigrant students compared to natives with the same performance in standardized tests. Differences in grading are bigger for teachers with stronger stereotypes, elicited through an Implicit Associa-tion Test (IAT). We reveal teachers their own IAT score, randomizing the timing of disclosure. Teachers informed before grading increase grades assigned to immigrants. This result is driven by teachers who do not report explicit views against immigrants and who receive a more precise signal of their implicit bias.

Alberto Alesina, Michela Carlana, Eliana La Ferrara, Paolo Pinotti

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Workshop / Seminar Thu, 31 Oct 2019 10:34:37 -0400 2019-11-22T13:00:00-05:00 2019-11-22T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Public Finance: Optimal Noise in Second Best (November 25, 2019 4:00pm) https://events.umich.edu/event/67505 67505-16866611@events.umich.edu Event Begins: Monday, November 25, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

Noise can be efficiently introduced by a decision-maker into data to protect identity (differential privacy) or to reduce gaming between a decision-maker and an agent who can the manipulate data. We present a new benefit of noise: to efficiently reduce distortions in a second-best setting. We derive a condition---which quickly converges to standard DARA preferences in the number of agents---where the introduction of noise in the private provision of public goods is Pareto improving. Despite producing a risk cost, noise reduces free-riding, which is more valuable under our condition. The effect is large: total Nash giving, while still less than first best, now diverges in the number of donors instead of converges (the standard result). A second application relates to tax.

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Workshop / Seminar Mon, 25 Nov 2019 08:30:08 -0500 2019-11-25T16:00:00-05:00 2019-11-25T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Armagan Bayram, PhD (November 25, 2019 4:30pm) https://events.umich.edu/event/69641 69641-17374460@events.umich.edu Event Begins: Monday, November 25, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Virtual appointments between patients and healthcare providers can offer a cost-effective alternative to traditional office appointments for managing chronic conditions. Virtual appointments increase contact with the physician by either substituting or complementing office appointments, leading to improved health outcomes. The true value of virtual appointments cannot be realized until they are truly integrated with the office appointment systems. In this study, we introduce a capacity allocation model to study the use of virtual appointments in a chronic care setting. Specifically, we develop a finite horizon stochastic dynamic program to determine which patients to schedule for office and virtual appointments that maximizes aggregate health benefits across a cohort of patients. Optimal policy characterization for this problem is challenging. We find that under certain conditions, a myopic heuristic, where the sickest patients are scheduled for office appointments and the next sickest patients are scheduled for virtual appointments, is optimal. We show that the myopic heuristic performs well even in more general settings. Our findings further show that virtual appointments serve a dual purpose: they may reduce the number of office appointments and may trigger follow-up office appointments.

Dr. Armagan Bayram is an assistant professor in the Department of Industrial and Manufacturing Systems Engineering at University of Michigan – Dearborn. She worked as a postdoctoral fellow in the Department of Industrial Engineering and Management Sciences at Northwestern University. She received her Ph.D. in Management Science from the University of Massachusetts Amherst and M.S. and B.S. degrees in Industrial Engineering from Istanbul Technical University. Dr. Bayram’s research interests include the development of stochastic models and solution methods for capacity and resource allocation problems. Of particular interest are stochastic optimization and dynamic programming models that involve nonprofit and healthcare applications.

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: http://www.bme.umich.edu/about/directions.php.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 20 Nov 2019 10:45:52 -0500 2019-11-25T16:30:00-05:00 2019-11-25T18:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Center for Healthcare Engineering & Patient Safety
Health, History, Demography & Development (H2D2) (November 26, 2019 11:30am) https://events.umich.edu/event/68834 68834-17161714@events.umich.edu Event Begins: Tuesday, November 26, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 25 Oct 2019 10:22:54 -0400 2019-11-26T11:30:00-05:00 2019-11-26T12:50:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Primate patience: from foraging to cooperation (December 2, 2019 11:45am) https://events.umich.edu/event/68616 68616-17105377@events.umich.edu Event Begins: Monday, December 2, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

Intertemporal choices involving tradeoffs between benefits and time costs are ubiquitous in both human and animal lives. Several proposals argue that nonhumans are stuck in the ‘now’, whereas future-orienting cognition allows humans to think ahead and make adaptive decisions. What is the ultimate function of high levels of patience, and why do such abilities emerge? I will argue that a suite of decision-making capacities including inter-temporal choice and future planning evolved in the context of foraging behaviors, and vary with ecological complexity across species. Then, I will examine how these capacities for self-control can be generalized from foraging contexts to solve new but evolutionarily-important problems, like cooking food. Finally, I will present work testing the hypothesis that low levels of self-control constrain cooperation in primates, and therefore may explain human-unique forms of ultra-sociality.

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Workshop / Seminar Fri, 18 Oct 2019 14:00:09 -0400 2019-12-02T11:45:00-05:00 2019-12-02T12:45:00-05:00 North Quad Department of Economics Workshop / Seminar economics
Cognitive Science Seminar: Task sets serve as boundaries for the congruency sequence effect (December 2, 2019 3:00pm) https://events.umich.edu/event/67488 67488-16864387@events.umich.edu Event Begins: Monday, December 2, 2019 3:00pm
Location: Weiser Hall
Organized By: Weinberg Institute for Cognitive Science

Psychology PhD student Lauren Grant will present "Task sets serve as boundaries for the congruency sequence effect."

ABSTRACT

Cognitive control processes that enable purposeful behavior are often context-specific. A teenager, for example, may inhibit the tendency to daydream at work but not in the classroom. However, the nature of contextual boundaries for cognitive control processes remains unclear. We therefore revisited an ongoing controversy over whether such boundaries reflect (1) an attentional reset that occurs whenever a context-defining (e.g., sensory) feature changes or (2) a disruption of episodic memory retrieval that occurs only when the updated context-defining feature is linked to a different task set. To distinguish between these hypotheses, we employed a cross-modal distractor-interference task to determine precisely when changing a salient context-defining feature – the sensory modality in which task stimuli appear – bounds control processes underlying the congruency sequence effect (CSE). Consistent with the task set hypothesis, but not with the attentional reset hypothesis, Experiments 1 and 2 revealed that changing the sensory modality in which task stimuli appear eliminates the CSE only when the task structure enables participants to form modality-specific task sets. Experiment 3 further revealed that such “modality-specific” CSEs are associated with orienting attention to the sensory modality in which task stimuli appear, which may facilitate the formation of a modality-specific task set. These findings support the view that task sets serve as boundaries for the CSE.

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Lecture / Discussion Mon, 25 Nov 2019 13:22:47 -0500 2019-12-02T15:00:00-05:00 2019-12-02T16:30:00-05:00 Weiser Hall Weinberg Institute for Cognitive Science Lecture / Discussion Weiser Hall
Public Finance: Anti Insurance: The Perverse Targeting of Health Insurance (December 2, 2019 4:00pm) https://events.umich.edu/event/67506 67506-16866612@events.umich.edu Event Begins: Monday, December 2, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

Health insurance typically covers not only the small probability, large loss events emphasized by theory but also routine services like regular checkups. Usage of such services responds to liquidity shocks; people cut back when times are tight, such as during an unemployment spell. As a result, coverage of such services is least valuable in the states of the world in which marginal utility is greatest---an anti-insurance effect. Whether the net effect of health insurance is to improve or worsen risk exposure depends on the insured's relative exposure to health versus non-health risks. I find that for many U.S. households, health insurance worsens risk exposure; on average it targets states of the world in which marginal utility is relatively low. This highlights an important cost of the many policies that subsidize health insurance or health care.

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Workshop / Seminar Tue, 08 Oct 2019 08:14:43 -0400 2019-12-02T16:00:00-05:00 2019-12-02T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Leia Stirling, PhD (December 2, 2019 4:30pm) https://events.umich.edu/event/69766 69766-17417431@events.umich.edu Event Begins: Monday, December 2, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Wearable sensors provide opportunity to augment occupational therapy through telemedicine. However, there are several design challenges embedded in creating an at-home telemonitoring system that can visualize the complex biomechanical data required for clinical decision making. These challenges include defining performance metrics that correspond to clinical needs and being able to robustly make these measures in a natural environment. In this talk, we describe quantified metrics of motion coordination, balance strategy, and torso compensatory motions. These metrics were informed by clinical observations and were features monitored and synthesized to adapt the selected patient activities.

Leia Stirling is an Associate Professor in Industrial and Operations Engineering at the University of Michigan. Her research quantifies human performance and human-machine fluency to assess performance augmentation, advance exoskeleton control algorithms, mitigate injury risk, and provide relevant feedback to subject matter experts across domains. She received her B.S. (2003) and M.S. (2005) in Aeronautical and Astronautical Engineering from the University of Illinois at Urbana-Champaign, and her Ph.D. (2008) in Aeronautics and Astronautics from MIT. She was a postdoctoral researcher at Boston Children’s Hospital and Harvard Medical School (2008-2009), on the Advanced Technology Team at the Wyss Institute for Biologically Inspired Engineering (2009-2012), then an Assistant Professor at MIT (2013 – 2019). She joined the faculty at the University of Michigan in 2019.

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: http://www.bme.umich.edu/about/directions.php.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Mon, 25 Nov 2019 13:25:13 -0500 2019-12-02T16:30:00-05:00 2019-12-02T18:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Leia Stirling, PhD
Department of Human Genetics 2019 Seminar Series (December 3, 2019 4:00pm) https://events.umich.edu/event/69796 69796-17425664@events.umich.edu Event Begins: Tuesday, December 3, 2019 4:00pm
Location: Buhl Res Cen for Human Genetics
Organized By: Department of Human Genetics

Dr. Dernburg will be presenting a seminar entitled, "Pairing and Patterning between Meiotic Chromosomes" on Tuesday, December 3, 2019 in the Buhl 5915 Classroom, 1241 Catherine Street, on the medical school campus. The seminar will begin at 4:00 pm, with light refreshments before the start of the seminar.

For more information, call 734-647-3149.






Presented by:





Abby Dernburg, Ph.D.
HHMI Investigator
Department of Molecular and Cell Biology
University of California, Berkeley





Tuesday, December 3, 2019
4:00-5:00 PM
5915 Buhl Classroom

Hosted by: Callie Swanepoel

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Lecture / Discussion Tue, 26 Nov 2019 14:19:16 -0500 2019-12-03T16:00:00-05:00 2019-12-03T17:00:00-05:00 Buhl Res Cen for Human Genetics Department of Human Genetics Lecture / Discussion Buhl Building, 1241 Catherine St.
MIPSE Seminar | The Schwinger Plasma: An Experimental Program to Study the Plasmas That Exist Inside the Vacuum (December 4, 2019 3:30pm) https://events.umich.edu/event/65977 65977-16678380@events.umich.edu Event Begins: Wednesday, December 4, 2019 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The most fundamental plasma is the quantum vacuum, but it remains largely inaccessible to experiments because of the energy scales involved. The minimum temperature required to “ionize” the vacuum is equivalent to the mass of an electron-positron pair, 1 MeV, or about 10^10K. One way to imagine creating an e^+e^- plasma out of “nothing” is through tunnel ionization of the vacuum by a laser; but simple scaling shows that the in-tensity required to reach the tunneling threshold must be more than 10^29 W/cm^2, which has been called the “Schwinger threshold”. This talk will introduce the experimental methods we will use to reach this regime, and what we might expect to find.

About the Speaker:
Phil Bucksbaum is the Marguerite Blake Wilbur Professor at Stanford University, with appointments in Physics, Applied Physics, and in Photon Science at SLAC. He also founded and directed the Stanford PULSE Institute (ultrafast.stanford.edu). He studies the interaction of intense coherent radiation with atoms and molecules, with emphasis on interactions induced by attosecond pulsed radiation and ultrashort x-ray lasers. Prior to Stanford, Bucksbaum was on the faculty at U. of Michigan, and on the research staff at Bell Laboratories. He received MA and PhD degrees in Physics from U. of California at Berkeley, and his AB degree in Physics, magna cum laude from Harvard College. He is Fellow of the American Physical Society and Optical Society of America and elected to the National Academy of Sciences and American Academy of Arts and Sciences. He was president of OSA in 2014 and is president-elect APS, where he will serve as president in 2020.

The seminar will be web-simulcast. To view the simulcast, please follow this link:
https://mipse.my.webex.com/mipse.my/j.php?MTID=mcece347060ae30ec7ab06503f5aa8baf
Meeting number: 623 577 400
Password: mipse19

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Lecture / Discussion Tue, 26 Nov 2019 11:06:42 -0500 2019-12-04T15:30:00-05:00 2019-12-04T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Philip Bucksbaum
Macroeconomics (December 4, 2019 4:00pm) https://events.umich.edu/event/68261 68261-17037417@events.umich.edu Event Begins: Wednesday, December 4, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Thu, 10 Oct 2019 13:11:51 -0400 2019-12-04T16:00:00-05:00 2019-12-04T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
International Economics (December 5, 2019 11:30am) https://events.umich.edu/event/68612 68612-17105372@events.umich.edu Event Begins: Thursday, December 5, 2019 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 18 Oct 2019 12:54:09 -0400 2019-12-05T11:30:00-05:00 2019-12-05T13:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Law and Economics: Tort Liability and Unawareness (December 5, 2019 4:30pm) https://events.umich.edu/event/68326 68326-17046003@events.umich.edu Event Begins: Thursday, December 5, 2019 4:30pm
Location: Jeffries Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 15:25:13 -0400 2019-12-05T16:30:00-05:00 2019-12-05T18:30:00-05:00 Jeffries Hall Department of Economics Workshop / Seminar economics
Applied Microeconomics/IO Seminar: The Equilibrium Effects of Public Provision in Education Markets: Evidence from a Public School Expansion Policy (December 6, 2019 10:00am) https://events.umich.edu/event/68281 68281-17037508@events.umich.edu Event Begins: Friday, December 6, 2019 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

In a variety of markets with private options, the optimal level of public provision may require balancing a tradeoff between reducing private options’ market power with the possibility of crowding out potentially high-quality products. These considerations are particularly relevant in many developing countries’ education systems where private schools capture high market shares while public schools are overcrowded. We study the equilibrium effects of public provision in the context of a large expansion of public schools in the Dominican Republic. Over a five-year period, the government aimed to increase the number of public school classrooms by 78%. Using an event study framework, we estimate the effect of a new public school on neighborhood outcomes and competing private schools, where we instrument for how quickly the public school construction project finished with whether the procurement lottery randomly assigned the project to a firm or an unaffiliated individual. We find that a new public increased neighborhood students’ test scores, both in the public and private sectors. As public enrollment increased, a large number of private schools closed while the surviving schools lowered prices and increased investment in school quality. To study how the provision of high quality schools varies with the level of public provision, and to compare the effects to the alternative policy of public financing, we specify an empirical model of demand (students choosing schools) and supply (schools choosing whether to stay open, how much to invest in quality, and what price to charge).

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Workshop / Seminar Mon, 02 Dec 2019 08:15:37 -0500 2019-12-06T10:00:00-05:00 2019-12-06T11:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Yuqi Gu, Ph.D. Candidate, Department of Statistics, University of Michigan (December 6, 2019 10:00am) https://events.umich.edu/event/69647 69647-17376499@events.umich.edu Event Begins: Friday, December 6, 2019 10:00am
Location: West Hall
Organized By: Department of Statistics

In modern psychological and biomedical research with diagnostic purposes, scientists often formulate the key task as inferring the fine-grained latent information under structural constraints. These structural constraints usually come from the domain experts’ prior knowledge or insight. The emerging family of Structured Latent Attribute Models (SLAMs) accommodate these modeling needs and have received substantial attention in psychology, education, and epidemiology. SLAMs bring exciting opportunities and unique challenges. In particular, with high-dimensional discrete latent attributes and structural constraints encoded by a design matrix, one needs to balance the gain in the model’s explanatory power and interpretability, against the difficulty of understanding and handling the complex model structure.

In the first part of this talk, I present identifiability results that advance the theoretical knowledge of how the design matrix influences the estimability of SLAMs. The new identifiability conditions guide real-world practices of designing cognitive diagnostic tests and also lay the foundation for drawing valid statistical conclusions. In the second part, I introduce a statistically consistent penalized likelihood approach to selecting significant latent patterns in the population. I also propose a scalable computational method. These developments explore an exponentially large model space involving many discrete latent variables, and they address the estimation and computation challenges of high-dimensional SLAMs arising in large-scale scientific measurements. The application of the proposed methodology to the data from an international educational assessment reveals meaningful knowledge structures and latent subgroups of the student populations.

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Workshop / Seminar Wed, 20 Nov 2019 13:22:35 -0500 2019-12-06T10:00:00-05:00 2019-12-06T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Yuqi Gu
ISD Manufacturing Seminar Series (December 6, 2019 11:00am) https://events.umich.edu/event/69423 69423-17480881@events.umich.edu Event Begins: Friday, December 6, 2019 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Join us Friday, December 6, 2019 from 11:00am-12:00pm in Chrysler Center, Room 151 (2121 Bonisteel Blvd, Ann Arbor) for our Manufacturing Seminar Series Speaker, with Anne Marie Habraken Ph.D. Dr. Habraken is Vice Dean of research of the Engineering School of the University of Liège since 2015. She was President of ESAFORM European Scientific Association for material FORMing from 2004 to 2008.

After a quick overview of the current state of solid, fluid or mixed type simulations of additive manufacturing processes, Dr. Habraken's lecture will be focused on the challenges of finite element predictions through 3 different cases.

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Lecture / Discussion Tue, 03 Dec 2019 11:09:32 -0500 2019-12-06T11:00:00-05:00 2019-12-06T12:00:00-05:00 Chrysler Center Integrative Systems + Design Lecture / Discussion MFG Seminar
MCDB Seminar: In Toto Imaging in Zebrafish Shows How Cells 'Build' Patterns (December 6, 2019 12:00pm) https://events.umich.edu/event/67363 67363-16839929@events.umich.edu Event Begins: Friday, December 6, 2019 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Cunming Duan

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Workshop / Seminar Tue, 17 Sep 2019 17:08:59 -0400 2019-12-06T12:00:00-05:00 2019-12-06T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar digital image fish embryo
Economics at Work (December 6, 2019 1:00pm) https://events.umich.edu/event/68600 68600-17105360@events.umich.edu Event Begins: Friday, December 6, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Fri, 18 Oct 2019 12:24:40 -0400 2019-12-06T13:00:00-05:00 2019-12-06T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Labor Economics: What is a Good School, and Can Parents Tell? Evidence on the Multidimensionality of School Output (December 6, 2019 1:00pm) https://events.umich.edu/event/68424 68424-17080057@events.umich.edu Event Begins: Friday, December 6, 2019 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract

Is a school’s impact on high-stakes test scores a good measure of its overall impact on students? Do parents value school impacts on tests, longer-run outcomes, or both? To answer the first question, we exploit quasi-random school assignments and data from Trinidad and Tobago. We construct exogenous instruments for each individual school and estimate the causal impacts of individual schools on several short- and longer-run outcomes. Schools’ impacts on high-stakes tests are weakly related to impacts on low-stakes tests, dropout, crime, teen motherhood, and formal labor market participation. To answer the second question, we link estimated school
impacts to parents’ ranked lists of schools. We propose a modified mulitnomial logit model that allows one to infer preferences for school attributes even in some settings where choices are strategic. Parents of higher-achieving students value schools that improve high-stakes test scores conditional on average outcomes, proximity, and even peer quality. Parents also value schools that reduce crime and increase formal labor market participation. Most parents’ preferences for school impacts on labor-market and crime outcomes are, as strong, or stronger than those for test scores. These results provide a potential explanation for recent findings that parent preferences are not strongly related to test-score impacts. They also suggest that evaluations based solely on test scores may be very misleading about the welfare effects of school choice.

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Workshop / Seminar Thu, 21 Nov 2019 10:09:43 -0500 2019-12-06T13:00:00-05:00 2019-12-06T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Economic Theory: Stability in Repeated Matching Markets (December 6, 2019 2:30pm) https://events.umich.edu/event/69031 69031-17220012@events.umich.edu Event Begins: Friday, December 6, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

I develop a framework for studying repeated matching markets, where in every period, a new generation of short-lived agents on one side of the market is matched to a fixed set of long-lived institutions on the other. Within this framework, I characterize self-enforcing arrangements for two types of environments. When wages are rigid, as in the matching market for hospitals and medical residents, players can be partitioned into two sets: regardless of patience level, some players can be assigned only according to a static stable matching; when institutions are patient, the other players can be assigned in ways that are unstable in one-shot interactions. I discuss these results’ implications for allocating residents to rural hospitals. When wages can be flexibly adjusted, I show that with flexible wages, repeated interaction resolves well-known non-existence issues: while static stable matchings may fail to exist with complementarities and/or peer effects, self-enforcing matching processes always exist if institutions are sufficiently patient.

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Workshop / Seminar Mon, 02 Dec 2019 09:34:45 -0500 2019-12-06T14:30:00-05:00 2019-12-06T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Social, Behavioral & Experimental Economics (SBEE): Borrowing to Save? The Impact of Automatic Enrollment on Debt (December 9, 2019 11:45am) https://events.umich.edu/event/68617 68617-17105383@events.umich.edu Event Begins: Monday, December 9, 2019 11:45am
Location: North Quad
Organized By: Department of Economics

Abstract

Does automatic enrollment into a retirement plan increase borrowing outside the plan? We study a natural experiment created when the U.S. Army began automatically enrolling newly hired civilian employees into the Thrift Savings Plan. Four years after hire, automatic enrollment causes no significant change in credit scores (point estimate 0.001 standard deviations) or debt balances excluding auto loans and first mortgages (point estimate -0.6% of annual salary). We also find no significant increase in auto loan and first mortgage balances in our main regression specification, although the estimated increases in these categories are economically and statistically significant in alternative specifications.

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Workshop / Seminar Tue, 19 Nov 2019 08:31:30 -0500 2019-12-09T11:45:00-05:00 2019-12-09T12:45:00-05:00 North Quad Department of Economics Workshop / Seminar economics
Cognitive Science Seminar Series (December 9, 2019 3:00pm) https://events.umich.edu/event/67490 67490-16864389@events.umich.edu Event Begins: Monday, December 9, 2019 3:00pm
Location: Weiser Hall
Organized By: Weinberg Institute for Cognitive Science

The biweekly Cognitive Science Seminar Series features informal presentations of work-in-progress by graduate students, post-docs, and faculty; networking and meeting other cognitive scientists and students on campus; reading groups that involve pairs of papers on the same topic from different disciplines; practice talks (especially talks that are interdisciplinary in nature or might be presented to an interdisciplinary audience); conference reports from cognitive science conferences; and occasional invited speakers of interest to the group.

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Lecture / Discussion Fri, 20 Sep 2019 11:41:52 -0400 2019-12-09T15:00:00-05:00 2019-12-09T16:30:00-05:00 Weiser Hall Weinberg Institute for Cognitive Science Lecture / Discussion Weiser Hall
Public Finance: “Does eviction cause poverty? Quasi-experimental evidence from Cook County, IL” (joint with John Eric Humphries, Nick Mader, and Daniel Tannenbaum) (December 9, 2019 4:00pm) https://events.umich.edu/event/66603 66603-16767943@events.umich.edu Event Begins: Monday, December 9, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:

Each year, more than two million U.S. households have an eviction case filed against them. Many cities have recently implemented policies aimed at reducing the number of evictions, motivated by research showing strong associations between being evicted and subsequent adverse economic outcomes. Yet it is difficult to determine to what extent those associations represent causal relationships, because eviction itself is likely to be a consequence of adverse life events. This paper addresses that challenge and offers new causal evidence on how eviction affects financial distress, residential mobility, and neighborhood quality. We collect the near-universe of Cook County court records over a period of seventeen years, and link these records to credit bureau and payday loans data. Using this data, we characterize the trajectory of financial strain in the run-up and aftermath of eviction court for both evicted and non-evicted households, finding high levels and striking increases in financial strain in the years before an eviction case is filed. Guided by this descriptive evidence, we employ two approaches to draw causal inference on the effect of eviction. The first takes advantage of the panel data through a difference-in-differences design. The second is an instrumental variables strategy, relying on the fact that court cases are randomly assigned to judges of varying leniency. We find that eviction negatively impacts credit access and durable consumption for several years. However, the effects are small relative to the financial strain experienced by both evicted and non-evicted tenants in the run-up to an eviction filing.

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Workshop / Seminar Fri, 06 Dec 2019 11:14:28 -0500 2019-12-09T16:00:00-05:00 2019-12-09T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
IOE 813 Seminar: Amy Cohn, PhD and Krishnan Raghavendran, MBBS (December 9, 2019 4:30pm) https://events.umich.edu/event/70022 70022-17497479@events.umich.edu Event Begins: Monday, December 9, 2019 4:30pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: U-M Industrial & Operations Engineering

Specializing in trauma, burn, surgical critical care, and emergency surgery areas, the surgeons in the Division of Acute Care Surgery at Michigan Medicine care for our most critically injured patients. Ensuring that this team is able to properly staff its units at all times is essential to Michigan Medicine’s mission and role as a Level 1 Trauma Center and Burn Verified Center. However, traditional methods for scheduling healthcare providers are time-intensive and may fail to meet the needs of the providers and units they serve. For Acute Care Surgery, the task of creating the schedules, which often follows a complex set of rules and preferences, falls on the Division Chief, consuming valuable time and sometimes not satisfying each surgeon’s preferences. To improve this process, we have created a computerized decision-making tool to ease the burden of creating such schedules. We formulated an integer program to automate the creation of this department’s six-month-long schedule, which assigns 15 attending surgeons to 5 units for weekly time intervals. Users can input schedule parameters such as the attending surgeons’ time-off requests and targeted number of weeks on service. Moreover, metrics enable generating the highest-quality schedule that simultaneously meets the needs of the department, the surgeons’ preferences, and balances the schedule fairly. This scheduling tool has drastically decreased the production time of the schedule. Whereas previously creating the six-month schedule required multiple weeks of the division chief’s time, using the scheduling tool requires only a few hours of the division chief’s time. Additionally, the transparent schedule metrics defined by the tool can increase a sense of fairness among surgeons, increasing job satisfaction and reducing physician burnout.

Amy Cohn, PhD, joined the faculty in the Department of Industrial and Operations Engineering at the University of Michigan in 2002 as an Assistant Professor and was promoted to Associate Professor in 2009; in 2011, she was also named a Thurnau Professor and in 2017 was promoted to Full Professor. She currently holds the position of Associate Director for the Center for Healthcare Engineering and Patient Safety. Her primary research interest is in robust and integrated planning for large-scale systems, predominantly in healthcare and aviation applications. She also collaborates on projects in satellite communications, vehicle routing problems for hybrid fleets, and robust network design for power systems and related applications. Her primary teaching interest is in optimization techniques, at both the graduate and undergraduate level.

Dr. Raghavendran is Professor of Surgery and the Division chief of Acute Care Surgery, Section of General Surgery. He received his medical education in India and immigrated to the United States in 1991, wherein he completed his Surgical Residency and subsequent fellowship in Surgical Critical Care Dr. Raghavendran has been continuously funded by the National Institutes of Health (NIH) from both NIGMS and NHLBI for the past 14 years. The current R-01 is on the study of Hypoxia-inducible factor 1 α in the pathogenesis of acute inflammatory response following lung contusion. The focus of his clinical interest is with ARDS and ventilator-associated pneumonia.He currently serves as the director of the newly formed Michigan Center for global surgery. Additionally, he serves as the lead physician for the University of Michigan India collaborative. He has also received funding from the NIH US/India collaborative with an R-03 award examining the role of ultrasound and measurement of optic nerve sheath diameter as a surrogate marker for traumatic brain injury.

1123 LBME is room 1123 in the Ann & Robert H. Lurie Biomedical Engineering Building (LBME). The street address is 1101 Beal Avenue. A map and directions are available at: http://www.bme.umich.edu/about/directions.php.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.

For additional information and to be added to the weekly e-mail for the series, please contact genehkim@umich.edu.

Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 05 Dec 2019 11:43:02 -0500 2019-12-09T16:30:00-05:00 2019-12-09T18:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) U-M Industrial & Operations Engineering Lecture / Discussion Amy Cohn, PhD and Krishnan Raghavendran, MBBS
ChE Seminar Series: Todd Emrick (December 10, 2019 1:30pm) https://events.umich.edu/event/69736 69736-17392935@events.umich.edu Event Begins: Tuesday, December 10, 2019 1:30pm
Location:
Organized By: Chemical Engineering

>>This Seminar will be held in the North Campus Research Complex, Building 32, Auditorium

ABSTRACT
"Designer Soft Materials and Hybrid Functional Interfaces"

This lecture will apply concepts and techniques of organic and polymer chemistry to materials targets, with the objective of producing new and useful structures for fundamental studies. The topics to be presented involve translating synthetic advances to creative materials applications, including the synthesis of new polymer zwitterions (including phosphorylcholines, sulfobetaines, and sulfothetins) that have generated a surprising breadth of advances, ranging from electronic materials to medical devices to injectable therapeutics. Striking properties of these polymers at interfaces will be discussed, including in thin films and in fluids, with focus on the impact of new functional polymers as components of ‘hard-soft’ materials interfaces. In addition, mesoscale materials constructs will be described, including a new kind of “mesoscale block copolymers” (MSBCPs) that are envisaged as larger scale analogs of conventional block copolymers, as well as nanocomposite hydrogels that function as photo-induced surfers and motors at air-fluid interfaces.

BIO
Todd Emrick is a Professor of Polymer Science and Engineering at the University of Massachusetts Amherst, and adjunct faculty member at the UMass Medical School in Worcester, MA. He earned a B.S. in Chemistry from Juniata College in PA and Ph.D. in Organic Chemistry with Philip E. Eaton at the University of Chicago. Following postdoctoral work in polymer synthesis at the University of California Berkeley with Jean Fréchet, he began his independent position at UMass Amherst in 2001. While at UMass, his research has focused on the intersection of organic and polymer chemistry, with a focus on useful outlets in materials science and engineering. Advances from Todd’s laboratories have been recognized by the Carl S. Marvel Award for creative polymer chemistry (ACS Polymer Division), election to the National Academy of Inventors, and selection as the UMass Amherst College of Natural Sciences Outstanding Researcher. He is the prior Director of the NSF-supported Materials Research Science and Engineering Center (MRSEC) on Polymers at UMass Amherst (2008-2017) and is currently an investigator in the NSF Center for Chemomechanical Assembly (CCMA).

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Lecture / Discussion Fri, 22 Nov 2019 15:56:11 -0500 2019-12-10T13:30:00-05:00 2019-12-10T14:30:00-05:00 Chemical Engineering Lecture / Discussion North Campus Research Complex, Building 28
Economic History (December 10, 2019 2:30pm) https://events.umich.edu/event/68318 68318-17045994@events.umich.edu Event Begins: Tuesday, December 10, 2019 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Fri, 11 Oct 2019 14:51:33 -0400 2019-12-10T14:30:00-05:00 2019-12-10T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Statistics Department Seminar Series: Zheng Gao, Ph.D. Candidate, Department of Statistics, University of Michigan (December 10, 2019 4:00pm) https://events.umich.edu/event/69697 69697-17382665@events.umich.edu Event Begins: Tuesday, December 10, 2019 4:00pm
Location: West Hall
Organized By: Department of Statistics

We shall revisit some phase transitions in high-dimensional multiple testing problems under sparsity assumptions, and then proceed to characterize some new ones that we recently discovered. In particular, I will describe the signal sizes necessary and sufficient for statistical procedures to simultaneously control false discovery (in terms of family-wise error rate or false discovery rate) and missed detection (in terms of family-wise non-discovery rate or false non-discovery rate) in the simple but ubiquitous signal-plus-noise model

x(i) = \mu(i) + \epsilon(i), \quad i=1,2,\ldots,p

Several well-known procedures are shown to attain said boundaries. Remarkably, these phase transition phenomena continue to hold under a much wider class of models, and under extremely weak dependence assumptions. We provide point-wise, rather than minimax, results, wherever we can. Important practical implications, along with an interesting manifestation of the phase transitions in genome-wide association studies (GWAS), will be discussed.

Behind the statistical results is a probabilistic phenomenon known as relative stability. Much like how the law of large numbers describes the concentration of averages, relative stability --- or the "law of large dimensions" --- describes the concentration of maxima. We provide a complete characterization of the relative stability phenomenon for Gaussian triangular arrays in terms of their correlation structure. Its proof uses classic Sudakov-Fernique and Slepian lemma arguments along with a curious application of Ramsey's coloring theorem.

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Workshop / Seminar Tue, 26 Nov 2019 15:09:11 -0500 2019-12-10T16:00:00-05:00 2019-12-10T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Zheng Gao
BME Seminar: Alexandra Rutz (December 11, 2019 9:00am) https://events.umich.edu/event/69696 69696-17382664@events.umich.edu Event Begins: Wednesday, December 11, 2019 9:00am
Location: Electrical Engineering and Computer Science Building
Organized By: Biomedical Engineering

Remarkable advances in medicine and biology have been made possible with bioelectronics – devices that bridge and connect the worlds of living systems and electronics. Bioelectronics include wearable sensors for health monitoring, in vitro diagnostics, therapeutic implantable devices, and electrical stimulation for tissue engineering and regeneration. Despite their influence, bioelectronic devices are still limited by the fact that they are disparate and distinct from biology. The quality of the device-tissue interface is poor and diminishes with time; this is thought to be due to many factors including significant surgical trauma, an aggressive foreign body response, poor material compatibility with the biological milieu, as well as imprecise and distant connections between electronics and surrounding cells or tissues. Towards addressing these challenges, I will first present the use of slippery surfaces for mitigating the consequences of implanting bioelectronics into delicate tissues. I will demonstrate how liquid-infused elastomers reduce tissue deformation and tearing associated with the insertion of intracortical probes in rats. I will then present how, unlike typical electronic fabrication processes, additive manufacturing is compatible with biomaterials and cells. I will demonstrate that when “inks”, processing methods, and scaffold structure are engineered appropriately, extrusion-based 3D printing affords patterned, viable, and functional cell networks, and I will discuss how this can be exploited in future bioelectronic devices. To conclude, I will briefly present my vision to continue tackling the pressing challenges of biointegration that bioelectronics face in expanding their clinical and scientific impacts. The Rutz Lab will engineer “electronic tissues” that merge electronics and biology using additive manufacturing and biomaterials approaches.

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Lecture / Discussion Thu, 21 Nov 2019 10:42:20 -0500 2019-12-11T09:00:00-05:00 2019-12-11T10:00:00-05:00 Electrical Engineering and Computer Science Building Biomedical Engineering Lecture / Discussion BME Logo
Macroeconomics - CANCELLED (December 11, 2019 4:00pm) https://events.umich.edu/event/68262 68262-17037418@events.umich.edu Event Begins: Wednesday, December 11, 2019 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

*Please note that this seminar is cancelled!!

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Workshop / Seminar Tue, 03 Dec 2019 07:55:50 -0500 2019-12-11T16:00:00-05:00 2019-12-11T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar economics
Poetry & Ethnography: Expanding the Narrative (December 13, 2019 12:00pm) https://events.umich.edu/event/70194 70194-17547062@events.umich.edu Event Begins: Friday, December 13, 2019 12:00pm
Location: West Hall
Organized By: Department of Anthropology

December 13, 2019
Writing Workshop 12 - 2 pm
111 West Hall
Public Lecture 4 - 5:30 pm
Hatcher Graduate Library Gallery

Please join us for the second event of the
Anthropology & Poetry Speaker and Workshop Series. All students, faculty, and staff are welcome.

The generative writing workshop will be held in 111 West Hall from 12 - 2:00 pm. Participants are invited to bring their own materials (field notes, interview transcriptions, photos, etc.) to work with during the writing workshop, although this is not required. No prior experience with poetry is necessary. Lunch will be provided.

The public lecture will be held in the Hatcher Gallery from 4:00 - 5:30 pm.
Refreshments will be provided.

Kenzie Allen is a descendant of the Oneida Nation of Wisconsin. She is currently a lecturer at York University, and an R1-Advanced Opportunity Program Fellow and PhD Candidate in English & Creative Writing at the University of Wisconsin—Milwaukee. Her research centers on documentary and visual poetics, literary cartography, and the enactment of Indigenous sovereignties through creative works. Kenzie’s most recent project is a multimodal book of poetry which incorporates intergenerational histories and diasporic movements, Haudenosaunee traditions, and archival materials of the Carlisle Indian Boarding School. She received her MFA in Poetry from the Helen Zell Writers’ Program at the University of Michigan, and her BA in Anthropology from Washington University in St. Louis. Her poems can be found in Boston Review, Narrative Magazine, Best New Poets, and other venues, and she is the founder and managing editor of the Anthropoid collective.

Thank you to our sponsors: Department of Anthropology, Rackham Graduate School, Department of English Language and Literature, Department of American Culture, Native American Studies, Native American and Indigenous Studies Interest Group, Institute for the Humanities, LSA, Poetry & Poetics Workshop, Latina/o Studies, and the Center for Latin American and Caribbean Studies.

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Workshop / Seminar Wed, 11 Dec 2019 09:45:59 -0500 2019-12-13T12:00:00-05:00 2019-12-13T14:00:00-05:00 West Hall Department of Anthropology Workshop / Seminar Oneida Big Apple Fest
Poetry & Ethnography: Expanding the Narrative (December 13, 2019 4:00pm) https://events.umich.edu/event/70194 70194-17547063@events.umich.edu Event Begins: Friday, December 13, 2019 4:00pm
Location: Hatcher Graduate Library
Organized By: Department of Anthropology

December 13, 2019
Writing Workshop 12 - 2 pm
111 West Hall
Public Lecture 4 - 5:30 pm
Hatcher Graduate Library Gallery

Please join us for the second event of the
Anthropology & Poetry Speaker and Workshop Series. All students, faculty, and staff are welcome.

The generative writing workshop will be held in 111 West Hall from 12 - 2:00 pm. Participants are invited to bring their own materials (field notes, interview transcriptions, photos, etc.) to work with during the writing workshop, although this is not required. No prior experience with poetry is necessary. Lunch will be provided.

The public lecture will be held in the Hatcher Gallery from 4:00 - 5:30 pm.
Refreshments will be provided.

Kenzie Allen is a descendant of the Oneida Nation of Wisconsin. She is currently a lecturer at York University, and an R1-Advanced Opportunity Program Fellow and PhD Candidate in English & Creative Writing at the University of Wisconsin—Milwaukee. Her research centers on documentary and visual poetics, literary cartography, and the enactment of Indigenous sovereignties through creative works. Kenzie’s most recent project is a multimodal book of poetry which incorporates intergenerational histories and diasporic movements, Haudenosaunee traditions, and archival materials of the Carlisle Indian Boarding School. She received her MFA in Poetry from the Helen Zell Writers’ Program at the University of Michigan, and her BA in Anthropology from Washington University in St. Louis. Her poems can be found in Boston Review, Narrative Magazine, Best New Poets, and other venues, and she is the founder and managing editor of the Anthropoid collective.

Thank you to our sponsors: Department of Anthropology, Rackham Graduate School, Department of English Language and Literature, Department of American Culture, Native American Studies, Native American and Indigenous Studies Interest Group, Institute for the Humanities, LSA, Poetry & Poetics Workshop, Latina/o Studies, and the Center for Latin American and Caribbean Studies.

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Workshop / Seminar Wed, 11 Dec 2019 09:45:59 -0500 2019-12-13T16:00:00-05:00 2019-12-13T17:30:00-05:00 Hatcher Graduate Library Department of Anthropology Workshop / Seminar Oneida Big Apple Fest
Two stories: Insights into regulation of chromatin architecture by cryo-EM and cryo-ET (December 16, 2019 10:00am) https://events.umich.edu/event/69860 69860-17474745@events.umich.edu Event Begins: Monday, December 16, 2019 10:00am
Location: Palmer Commons
Organized By: Life Sciences Institute (LSI)

Two stories: Insights into regulation of chromatin architecture by cryo-EM and cryo-ET

Vignesh Kasinath, Ph.D.
Postdoctoral Fellow
University of California, Berkeley

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Lecture / Discussion Mon, 02 Dec 2019 15:22:24 -0500 2019-12-16T10:00:00-05:00 2019-12-16T11:00:00-05:00 Palmer Commons Life Sciences Institute (LSI) Lecture / Discussion
BME Ph.D. Defense: Amos Cao (December 19, 2019 10:00am) https://events.umich.edu/event/70078 70078-17507831@events.umich.edu Event Begins: Thursday, December 19, 2019 10:00am
Location: Lurie Robert H. Engin. Ctr
Organized By: Biomedical Engineering

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique that provides an unparalleled ability to non-invasive study brain activity. Since its inception in the early 1990s, fMRI has become a dominant tool in studying neurological responses to tasks and stimuli and has been critical in our evolving understanding of brain mapping. These achievements in neuroscience would not be possible without critical breakthroughs in MRI theory and hardware advancements, which continue to increase the speed and resolution of fMRI acquisitions. This dissertation explores a highly signal efficient fMRI imaging strategy known as Oscillating Steady-State Imaging (OSSI) and presents specialized artifact compensation strategies for addressing the practical challenges of the OSSI method.

First, we develop analytical models and simulations of OSSI, which describe how the signal magnitude varies as a function of frequency. These simulations are then used to study how respiration-induced frequency changes cause artifactual signal fluctuations to a signal timecourse. Our simulations show that the severity of respiration artifacts changes with initial off-resonance. Furthermore, we show that respiration artifacts are primarily caused by transient signal effects rather than changes to steady-state magnitude. These findings inform the two correction strategies proposed in the remainder of the dissertation.

The second portion of this work describes "OSSCOR," a retrospective method to correct timecourse magnitude changes caused by temporally varying frequency. We show how the OSSI signal exhibits a frequency-time duality that can be used to reshape structured physiological noise into a low-rank matrix. We then use principal component analysis in a data-driven correction strategy to create nuisance regressors for subsequent fMRI analysis. We also describe a variation of our method where free induction decay (FID) signals can be used to create nuisance regressors, referred to as ``F-OSSCOR.'' Both OSSCOR and F-OSSCOR were found to significantly improve the functional sensitivity and signal stability compared to polynomial detrending alone, and OSSCOR was also found to significantly outperform a standard data-driven correction method.

Finally, we present a prospective correction method which utilizes FID measurements to estimate and correct for B0 changes in real-time. Prospective correction has the potential to outperform retrospective correction methods by directly reducing perturbations to steady-state magnetization during acquisition. We first present the results of a feasibility analysis where simulation was used to determine how scan parameters would affect correction performance. We then developed a prospective correction application using the RTHawk platform to perform data analysis and parameter adjustment in real-time. Our initial fMRI proof-of-concept shows that real-time correction can increase the number of activated voxels and improve overall image stability as measured by temporal SNR.

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Workshop / Seminar Fri, 06 Dec 2019 13:00:13 -0500 2019-12-19T10:00:00-05:00 2019-12-19T10:00:00-05:00 Lurie Robert H. Engin. Ctr Biomedical Engineering Workshop / Seminar BME Event
Cryo-EM/ET, a Tool to Dissect Structural Mechanisms of Neurodegenerative Diseases (January 8, 2020 11:00am) https://events.umich.edu/event/69862 69862-17474746@events.umich.edu Event Begins: Wednesday, January 8, 2020 11:00am
Location: Palmer Commons
Organized By: Life Sciences Institute (LSI)

Cryo-EM/ET, a Tool to Dissect Structural Mechanisms of Neurodegenerative Diseases

Qiang Guo, Ph.D.
Postdoctoral Fellow
Max Planck Institute of Biochemistry

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Lecture / Discussion Mon, 02 Dec 2019 15:24:40 -0500 2020-01-08T11:00:00-05:00 2020-01-08T12:00:00-05:00 Palmer Commons Life Sciences Institute (LSI) Lecture / Discussion
Cryo-ET Seminar: Architecture of the human nuclear pore complex (January 13, 2020 10:00am) https://events.umich.edu/event/69863 69863-17474748@events.umich.edu Event Begins: Monday, January 13, 2020 10:00am
Location: Palmer Commons
Organized By: Life Sciences Institute (LSI)

Cryo-ET Seminar: Architecture of the human nuclear pore complex

Shyamal Mosalganti, Ph.D.
Postdoctoral Fellow
European Molecular Biology Laboratory

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Lecture / Discussion Mon, 02 Dec 2019 15:26:30 -0500 2020-01-13T10:00:00-05:00 2020-01-13T11:00:00-05:00 Palmer Commons Life Sciences Institute (LSI) Lecture / Discussion
Heterochromatin Organization and Dynamics- Department of Biological Chemistry Seminar (January 14, 2020 12:00pm) https://events.umich.edu/event/70990 70990-17766487@events.umich.edu Event Begins: Tuesday, January 14, 2020 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Serena Sanulli, Postdoctoral Fellow in the Department of Pharmaceutical Chemistry at UCSF, will give a seminar in the Department of Biological Chemistry on Tuesday 1/14/20 at 12:00pm in North Lecture Hall, MS II.

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Workshop / Seminar Tue, 07 Jan 2020 06:42:55 -0500 2020-01-14T12:00:00-05:00 2020-01-14T13:00:00-05:00 Medical Science Unit II Biological Chemistry Workshop / Seminar Sanulli
Cryo-electron tomography visualizes the ciliary complexes in action (January 15, 2020 11:00am) https://events.umich.edu/event/69864 69864-17474749@events.umich.edu Event Begins: Wednesday, January 15, 2020 11:00am
Location: Palmer Commons
Organized By: Life Sciences Institute (LSI)

Cryo-electron tomography visualizes the ciliary complexes in action

Jianfeng Lin, Ph.D.
Field Applications Scientist
Thermo Fisher Scientific, Waltham

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Lecture / Discussion Mon, 02 Dec 2019 15:28:18 -0500 2020-01-15T11:00:00-05:00 2020-01-15T12:00:00-05:00 Palmer Commons Life Sciences Institute (LSI) Lecture / Discussion
MIPSE Seminar | Will this Thruster Get Us to Europa? Modeling Ion Engine Erosion and Quantifying Lifetime Margins and Uncertainty (January 15, 2020 3:30pm) https://events.umich.edu/event/70791 70791-17644316@events.umich.edu Event Begins: Wednesday, January 15, 2020 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Solar electric propulsion (EP) is a key technology for human and robotic space missions, and is part of NASA’s vision for expanding human presence beyond low earth orbit. The high specific impulse of EP enables reductions in propellant mass, but at the price of long burn times. Deep space missions re-quire operating times of many 104 hours. Demonstrating that the thruster meets this requirement is a challenge. Multiple life tests of the full mission duration are not practical. The life capability must be demonstrated by combining physics-based modeling and short duration testing.
JPL developed the CEX2D and CEX3D codes to model erosion of ion accelerator systems in ion engines, a dominant failure mechanism. The codes model a primary ion beamlet and charge exchange (CEX) ions from the beamlet. Impingement of main, beamlet, and CEX ions on the grids then determine erosion rates. The models predict time-to-failure, but key questions include: What is the uncertainty in those estimates? How much margin is needed to account for the uncertainties? Estimating uncertainty in experiments is routine, but the modeling community is still developing techniques for estimating errors. In this talk we discuss the physical processes of ion engine grid erosion, how they are modeled, and methods for quantifying model uncertainty and required life margins.

About the speaker:
Dr. Polk is a Principal Engineer in the Propulsion, Materials, and Thermal Engineering Section at the Jet Propulsion Lab, and a lecturer in Aerospace Engr. at Caltech. He received a BS in Aero. Engr. at Georgia Tech and a PhD in Mech. & Aero. Engr. from Princeton. Dr. Polk is an expert in high-current cathode physics, EP wear processes, high power EP, and probabilistic methods to analyze engine life. He was the task manager for an 8200 hour wear test of a 2.3 kW ion engine as used on the Deep Space 1 mission, was a co-investigator in the Next Generation Ion Propulsion Program and principal investigator of the Nuclear Electric Xenon Ion System program. From 1997 to 2001 he was supervisor of the Advanced Propulsion Group at JPL. He now manages JPL’s high power EP tasks and is the Deputy Ion Propulsion System Lead for the Advanced EP System for the Lunar Gateway. He has authored over 100 papers and has received 7 best paper awards at the Intl. EP Conference and the Joint Propulsion Conference.

The seminar will be web-simulcast. To view the simulcast, please follow this link:
https://mipse.my.webex.com/mipse.my/j.php?MTID=mbd38de4eb55d697d214347b83b23fbd7
Meeting number: 621 559 684
Password: MIPSE20

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Lecture / Discussion Tue, 14 Jan 2020 08:20:47 -0500 2020-01-15T15:30:00-05:00 2020-01-15T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Jay Polk
DCMB Weekly Seminar (January 15, 2020 4:00pm) https://events.umich.edu/event/70964 70964-17760238@events.umich.edu Event Begins: Wednesday, January 15, 2020 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract: Synchronization occurs all around us. It underlies how fireflies flash as one, how human heart cells beat in unison, and how superconductors conduct electricity with no resistance. Synchronization is present in the precision of the cell cycle, and we can explore how breakdown of precision leads to disease. The many unique and fundamental functions of different cell types are achieved over and over independently, through a form of synchronization involving choreography of many proteins and genes. I will share a general historic and descriptive introduction to synchrony, including the classic work of Alan Turing. I will present some new work done jointly with Cleve Moler (MathWorks) and Steve Smale (UC Berkeley), where biology has inspired us to build new mathematical techniques to explore synchrony and its breakdown.

BlueJeans Livestream: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc

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Lecture / Discussion Mon, 06 Jan 2020 15:39:08 -0500 2020-01-15T16:00:00-05:00 2020-01-15T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Statistics Department Seminar Series: Yixin Wang, Ph.D. Candidate, Department of Statistics, Columbia University (January 17, 2020 10:00am) https://events.umich.edu/event/69914 69914-17483044@events.umich.edu Event Begins: Friday, January 17, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Causal inference from observational data is a vital problem, but it comes with strong assumptions. Most methods assume that we observe all confounders, variables that affect both the causal variables and the outcome variables. But whether we have observed all confounders is a famously untestable assumption. We describe the deconfounder, a way to do causal inference from observational data allowing for unobserved confounding.

How does the deconfounder work? The deconfounder is designed for problems of multiple causal inferences: scientific studies that involve many causes whose effects are simultaneously of interest. The deconfounder uses the correlation among causes as evidence for unobserved confounders, combining unsupervised machine learning and predictive model checking to perform causal inference. We study the theoretical requirements for the deconfounder to provide unbiased causal estimates, along with its limitations and tradeoffs. We demonstrate the deconfounder on real-world data and simulation studies.

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Workshop / Seminar Fri, 10 Jan 2020 11:21:57 -0500 2020-01-17T10:00:00-05:00 2020-01-17T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Yixin Wang
Electronics in the Brain – Literally (January 17, 2020 1:00pm) https://events.umich.edu/event/71584 71584-17842691@events.umich.edu Event Begins: Friday, January 17, 2020 1:00pm
Location: Gerald Ford Library
Organized By: Electrical and Computer Engineering

Abstract

Reading the human mind by electronic means used to be the domain of science fiction – and is still largely so. At the same time, technologies collectively labelled as brain-computer interfaces have moved forward, motivated by needs for assistive tools for neurologically impaired people and to advance our fundamental understanding of the brain. An applied example would be the use of electronic means to read out directly from the brain the intention to move an arm or a hand, and to decipher such signals to actuate an external robotic device. Another example is the
reading out brain signals produced when listening to or formulating speech. To access brain’s microcircuits at high space-time resolution requires implantation of electronic listening posts, call them nodes, at a number of nearby locations in a given functional area of the cortex. Which brings up the question of the day for neuroengineers: how many nodes might be required or are possible to implant, and how does one physically implement arrays of microscale electronic probes? What are the data rates involved in extracting brain signals and how to design a communication link to send the data onward for decoding by external computing platforms? What about reversing the direction of the process to use implanted probes to deliver signals directly into the brain (‘write-in’)? Through contemporary examples, this presentation will review recent accomplishments in the field from an electrical engineer’s viewpoint and discuss both the challenges and opportunities ahead to build next generations of brain-computer interfaces while explicitly exploiting many of the early 21st century advances in microelectronics, telecommunication, and high end computing.

Bio

Arto V. Nurmikko, a native of Finland, is a L. Herbert Ballou University Professor of Engineering and Physics at Brown. He received his degrees from University of California, Berkeley, with postdoctoral stays at MIT and Hebrew University. Professor Nurmikko conducts research in neuroengineering, brain sciences, nanophotonics and microelectronics, especially for the translation of device research to new technologies in biomedical, life science, and photonics applications. His current interests include development of implantable brain communication interfaces, microscale neural circuit sensors, compact semiconductor lasers, and high resolution acoustic microscopy. Professor Nurmikko is a Fellow of the American Physical Society, Fellow of the Institute of Electrical and Electronics Engineers, and Fellow of the Optical Society of America. He has been the recipient of a Guggenheim Fellowship, and elected to the American Academy of Arts and Sciences and to the Academy of Letters and Science of Finland. He was the co-recipient of the Israel Brain Prize in 2013.

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Lecture / Discussion Thu, 16 Jan 2020 11:10:47 -0500 2020-01-17T13:00:00-05:00 2020-01-17T14:30:00-05:00 Gerald Ford Library Electrical and Computer Engineering Lecture / Discussion Gerald Ford Library
Fluorescence Microscopy Tools to Illuminate RNA and Protein Dynamics in Live Cells (Department of Biological Chemistry Seminar) (January 21, 2020 12:00pm) https://events.umich.edu/event/71069 71069-17774925@events.umich.edu Event Begins: Tuesday, January 21, 2020 12:00pm
Location: Medical Science Unit II
Organized By: Biological Chemistry

Dr. Esther Braselmann, Postdoctoral Fellow at the University of Colorado Boulder, will be presenting the Department of Biological Chemistry Seminar on Tuesday 1/21/2020 at 12 noon in North Lecture Hall, MS II

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Workshop / Seminar Wed, 08 Jan 2020 07:18:32 -0500 2020-01-21T12:00:00-05:00 2020-01-21T13:00:00-05:00 Medical Science Unit II Biological Chemistry Workshop / Seminar
BME 500: Dr. Hua Wang (January 23, 2020 4:00pm) https://events.umich.edu/event/70066 70066-17505688@events.umich.edu Event Begins: Thursday, January 23, 2020 4:00pm
Location: Electrical Engineering and Computer Science Building
Organized By: Biomedical Engineering

Talk Overview:

Cancer immunotherapy has achieved significant clinical success in the past few years, but there remains tremendous room for the development of new-generation therapies with more robust and persistent antitumor immune responses. My research interests are largely directed towards understanding how cancer cells and immune cells can be manipulated or engineered using chemistry, material, and chemical biology approaches, in order to develop effective therapies for cancers, injured tissues, and other diseases. In this talk, I will start with my phd journey in exploring cancer-selective metabolic labeling and targeting, and then share how metabolic cell labeling can be utilized for tracking and targeted modulation of immune cells in vivo. Lastly, I will talk about a biomaterial-based antigen-free cancer vaccine for the treatment of poorly-immunogenic solid tumors.

Bio:

I am currently a Wyss Technology Development Fellow at Harvard University, aiming to integrate my research background in chemistry, materials science, and chemical biology with cancer immunotherapy and immunoengineering here. More specifically, I am exploring approaches to modulate or engineer cancer and immune cells in vivo, in order to improve and innovate current immunotherapies for cancers and other immune-related diseases. Before moving to Harvard, I earned my Ph.D. degree in Materials Science and Engineering at the University of Illinois at Urbana-Champaign (08/2012-06/2016), and my Bachelor’s degree in Polymer Science and Engineering at the University of Science and Technology of China (08/2008-06/2012).

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Workshop / Seminar Thu, 09 Jan 2020 09:54:33 -0500 2020-01-23T16:00:00-05:00 2020-01-23T17:00:00-05:00 Electrical Engineering and Computer Science Building Biomedical Engineering Workshop / Seminar Dr. Hua Wang
Statistics Department Seminar Series: Rina Foygel Barber, Associate Professor, Department of Statistics, University of Chicago (January 24, 2020 10:00am) https://events.umich.edu/event/69910 69910-17483043@events.umich.edu Event Begins: Friday, January 24, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: We introduce the jackknife+, a novel method for constructing predictive confidence intervals that is robust to the distribution of the data. The jackknife+ modifies the well-known jackknife (leave-one-out cross-validation) to account for the variability in the fitted regression function when we subsample the training data. Assuming exchangeable training samples, we prove that the jackknife+ permits rigorous coverage guarantees regardless of the distribution of the data points, for any algorithm that treats the training points symmetrically. Such guarantees are not possible for the original jackknife and we demonstrate examples where the coverage rate may actually vanish. Our theoretical and empirical analysis reveals that the jackknife and jackknife+ intervals achieve nearly exact coverage and have similar lengths whenever the fitting algorithm obeys some form of stability. We also extend to the setting of K-fold cross-validation. Our methods are related to cross-conformal prediction proposed by Vovk [2015] and we discuss connections.

This work is joint with Emmanuel Candes, Aaditya Ramdas, and Ryan Tibshirani.

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Workshop / Seminar Wed, 15 Jan 2020 10:18:08 -0500 2020-01-24T10:00:00-05:00 2020-01-24T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Rina Foygel Barber
Mfg Research, Smart Mfg Seminar Series: Dealing with streaming data for smart manufacturing (January 24, 2020 11:00am) https://events.umich.edu/event/71195 71195-17785626@events.umich.edu Event Begins: Friday, January 24, 2020 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Abstract
Recent advances in sensor arrays, imaging systems, as well as data science and AI open an exciting opportunity to rethink the way we assure and optimize performance and quality in the manufacturing industry. With the increasing availability of high-dimensional, streaming data in the industrial practice, it is now possible to predict impending anomalies and breakdowns across a manufacturing plant much earlier, and over considerably longer time horizons. Also, with the increasing availability of large time-series data, nonparametric machine learning approaches are becoming attractive for the prediction and prognosis of anomalies and breakdowns. This talk will overview three methods, each aimed at addressing a particular challenge with anomaly detection in smart manufacturing processes.
Speaker Bio
Satish T. S. Bukkapatnam received his Ph.D. and M.S. degrees in industrial and manufacturing engineering from the Pennsylvania State University. He currently serves as Rockwell International Professor with the Department of Industrial and Systems Engineering department at Texas A&M University, College Station, TX, USA. He is also the Director of Texas A&M Engineering Experimentation Station (TEES) Institute for Manufacturing Systems. His research in smart manufacturing addresses the harnessing of high-resolution nonlinear dynamic information, especially from wireless MEMS sensors, to improve the monitoring and prognostics, mainly of ultraprecision and nanomanufacturing processes and machines, and wearable sensors for cardiorespiratory processes. His research has led to over 160 peer-reviewed publications (101 published/accepted in journals and 68 in conference proceedings); five pending patents; $6 million in grants as PI/Co-PI from the National Science Foundation, the U.S. Department of Defense, and the private sector; and 14 best-paper/poster recognitions. He is a fellow of the Institute for Industrial and Systems Engineers (IISE), and the Society of Manufacturing Engineers (SME), and his work has been recognized with Oklahoma State University regents distinguished research, Halliburton outstanding college of engineering faculty, and Fulbright-Tocqueville distinguished chair awards.

Co-organized by:
Judy Jin (Program Director, ISD Manufacturing; Professor IOE)
Chinedum Okwudire (Associate Chair, ISD; Associate Professor, ME)

Contact Kathy Bishar at kbishar@umich.edu

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Workshop / Seminar Thu, 16 Jan 2020 09:19:16 -0500 2020-01-24T11:00:00-05:00 2020-01-24T12:00:00-05:00 Chrysler Center Integrative Systems + Design Workshop / Seminar Satish T.S. Bukkapatnam image
Investigating Protein Degradation at the Interface of Chemistry and Biology (January 28, 2020 11:45am) https://events.umich.edu/event/70908 70908-17735213@events.umich.edu Event Begins: Tuesday, January 28, 2020 11:45am
Location: Chemistry Dow Lab
Organized By: Department of Molecular, Cellular, and Developmental Biology

Faculty Candidate
Host: U. Jakob

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Workshop / Seminar Fri, 24 Jan 2020 13:28:03 -0500 2020-01-28T11:45:00-05:00 2020-01-28T12:45:00-05:00 Chemistry Dow Lab Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB initials on blue background
DCMB Seminar Series (January 29, 2020 4:00pm) https://events.umich.edu/event/71998 71998-17911963@events.umich.edu Event Begins: Wednesday, January 29, 2020 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk Title: Experimental and computational strategies to aid compound identification and quantitation in metabolomics

Abstract: Over the past two decades, metabolomics as a technique has moved from the primary domain of analytical chemists to more widespread acceptance by biologists, clinicians and bioinformaticians alike. Metabolomics offers systems-level insights into the critical roles small molecules play in routine cellular processes and myriad disease states. However, certain unique analytical challenges remain prominent in metabolomics as compared to the other ‘omics sciences. These include the difficulty of identifying unknown features in untargeted metabolomics data, and challenges maintaining reliable quantitation within lengthy studies that may span multiple laboratories. Unlike genomics and transcriptomics data in which nearly every quantifiable feature is confidently identified as a matter of course, in typical untargeted metabolomics studies over 80% of features are frequently not mapped to a specific chemical compound. Further, although many metabolomics studies have begun to stretch over a timeframe of years, data quantitation and normalization strategies have not always kept up with the requirements for such large studies. Fortunately, both experimental and computational strategies are emerging to tackle these long-standing challenges. We will report on several techniques in development in our laboratory, ranging from chromatographic fractionation and high-sensitivity data acquisition, to computational strategies to aid in tandem mass spectrometric spectral interpretation. These developments serve to facilitate analysis for both experts and novice users, which should ultimately help improve the biological insight and impact gained from metabolomics data.

BlueJeans livestreaming link: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc

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Lecture / Discussion Fri, 24 Jan 2020 11:07:13 -0500 2020-01-29T16:00:00-05:00 2020-01-29T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Statistics Department Seminar Series: Dylan Small, Professor, Department of Statistics, The Wharton School, University of Pennsylvania (January 31, 2020 10:00am) https://events.umich.edu/event/69915 69915-17483046@events.umich.edu Event Begins: Friday, January 31, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Gun violence is a problem in America. There are many unresolved questions about what policies would reduce gun violence. I will discuss two attempts at causal inference about gun violence prevention policies that I have worked on, and highlight some ideas about causal inference I have sought to use in this work.

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Workshop / Seminar Fri, 10 Jan 2020 12:13:43 -0500 2020-01-31T10:00:00-05:00 2020-01-31T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Dylan Small
Declare ECE! (January 31, 2020 11:30am) https://events.umich.edu/event/71415 71415-17825624@events.umich.edu Event Begins: Friday, January 31, 2020 11:30am
Location: Electrical Engineering and Computer Science Building
Organized By: Electrical and Computer Engineering

Seeking to declare your CoE major? Attend Declare ECE! and learn more about the exciting and innovative field of electrical engineering and computer engineering and how you can pursue an ECE degree!

Electrical and computer engineering is at the heart of modern technology and innovation, including computers, cars, robotics, energy and more. ECE will provide the skills you need to CHANGE THE WORLD and GET A JOB!!!

Pizza will be provided!

Visit our website to RSVP for the event.

Scheduled Activities at Event:

– Opening presentation from Professor P.C. Ku, Associate Chair of ECE Undergraduate Affairs

– Presentation on available events and activities for ECE students

– Panel of current ECE students

– Learn about Fall 2020’s EECS 200 that offers hands-on design, build, and test opportunities

– Learn about Major Design Experience (MDE) options

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Workshop / Seminar Tue, 14 Jan 2020 08:43:41 -0500 2020-01-31T11:30:00-05:00 2020-01-31T12:30:00-05:00 Electrical Engineering and Computer Science Building Electrical and Computer Engineering Workshop / Seminar Declare ECE! Photo
Economics at Work (January 31, 2020 1:00pm) https://events.umich.edu/event/70946 70946-17758141@events.umich.edu Event Begins: Friday, January 31, 2020 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Thu, 09 Jan 2020 10:58:56 -0500 2020-01-31T13:00:00-05:00 2020-01-31T14:10:00-05:00 Lorch Hall Department of Economics Workshop / Seminar Economics
BME Student Speaker: Xiaotian Tan (February 3, 2020 12:00pm) https://events.umich.edu/event/72234 72234-17963872@events.umich.edu Event Begins: Monday, February 3, 2020 12:00pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: Biomedical Engineering

Biosensors are devices or systems that can be used to detect, quantify, and analyze targets with biological activities and functions. As one of the largest subsets of biosensors, biomolecular sensors are specifically developed and programmed to detect, quantify and analyze biomolecules in liquid samples. Wide-ranging applications have made immunoassays increasingly popular for biomolecular detection and quantification. Among these, enzyme-linked immunosorbent assays (ELISA) are of particular interest due to high specificity and reproducibility. To some extent, ELISA has been regarded as a “gold standard” for quantifying analytes (especially protein analytes) in both clinical diagnostics and fundamental biological research. However, traditional (96-well plate-based) ELISA still suffers from several notable drawbacks, such as long assay time (4–6 hours), lengthy procedures, and large sample/reagent consumption (∼100 μL). These inherent disadvantages still significantly limit traditional ELISA's applicability to areas such as rapid clinical diagnosis of acute diseases (e.g., viral pneumonia, acute organ rejection), and biological research that requires accurate measurements with precious or low abundance samples (e.g., tail vein serum from a mouse). Thus, a bimolecular sensing technology that has high sensitivity, short assay time, and small sample/reagent consumption is still strongly desired. In this dissertation, we introduce the development of a multifunctional and automated optofluidic biosensing platform that can resolve the aforementioned problems. In contrast to conventional plate-based ELISA, our optofluidic ELISA platform utilizes mass-producible polystyrene microfluidic channels with a high surface-to-volume ratio as the immunoassay reactors, which greatly shortens the total assay time. We also developed a low-noise signal amplification protocol and an optical signal quantification system that was optimized for the optofluidic ELISA platform. Our optofluidic ELISA platform provides several attractive features such as small sample/reagent consumption (<8 μL), short total assay time (30-45 min), high sensitivity (~1 pg/mL for most markers), and a broad dynamic range (3-4 orders of magnitude). Using these features, we successfully quantified mouse FSH (follicle stimulating hormone) concentration with a single drop of tail vein serum. We also successfully monitored bladder cancer progression in orthotopic xenografted mice with only <50 μL of mouse urine. More excitingly, we achieved highly-sensitive exosome quantification and multiplexed immuno-profiling with <40 ng/mL of total input protein (per assay). These remarkable milestones could not be achieved with conventional plate-based ELISA but were enabled by our unique optofluidic ELISA.

As an emerging member of the bimolecular sensor family, our optofluidic ELISA platform provides a high-performance and cost-effective tool for a plethora of applications, including endocrinal, cancer animal model, cellular biology, and even forensic science research. In the future, this technology platform can also be renovated for clinical applications such as personalized cancer diagnosis/prognosis and rapid point-of-care diagnostics for infectious diseases.

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Lecture / Discussion Thu, 30 Jan 2020 09:19:52 -0500 2020-02-03T12:00:00-05:00 2020-02-03T13:00:00-05:00 Lurie Biomedical Engineering (formerly ATL) Biomedical Engineering Lecture / Discussion Xiaotian Tan
MCDB Remembering the past and rewiring the future: A protein-based inheritance paradigm (February 4, 2020 11:45am) https://events.umich.edu/event/70910 70910-17735215@events.umich.edu Event Begins: Tuesday, February 4, 2020 11:45am
Location: Chemistry Dow Lab
Organized By: Department of Molecular, Cellular, and Developmental Biology

Faculty Candidate
Host: R. Stockbridge

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Workshop / Seminar Fri, 24 Jan 2020 13:31:02 -0500 2020-02-04T11:45:00-05:00 2020-02-04T12:45:00-05:00 Chemistry Dow Lab Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB initials and yellow microscope on blue background
Temporal Regulation of the Blood-Brain Barrier (February 6, 2020 11:45am) https://events.umich.edu/event/70911 70911-17735216@events.umich.edu Event Begins: Thursday, February 6, 2020 11:45am
Location: Chemistry Dow Lab
Organized By: Department of Molecular, Cellular, and Developmental Biology

Faculty Candidate
Host: G. Csankovszki & Wilinski

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Workshop / Seminar Fri, 24 Jan 2020 13:28:56 -0500 2020-02-06T11:45:00-05:00 2020-02-06T12:45:00-05:00 Chemistry Dow Lab Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB initials and yellow microscope on blue background
Statistics Department Seminar Series: David Blei, Professor, Department of Statistics and Computer Science, Columbia University (February 7, 2020 10:00am) https://events.umich.edu/event/69917 69917-17483049@events.umich.edu Event Begins: Friday, February 7, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Causal inference from observational data is a vital problem, but it comes with strong assumptions. Most methods require that we observe all confounders, variables that affect both the causal variables and the outcome variables. But whether we have observed all confounders is a famously untestable assumption. We describe the deconfounder, a way to do causal inference with weaker assumptions than the classical methods require.

How does the deconfounder work? While traditional causal methods measure the effect of a single cause on an outcome, many modern scientific studies involve multiple causes, different variables whose effects are simultaneously of interest. The deconfounder uses the correlation among multiple causes as evidence for unobserved confounders, combining unsupervised machine learning and predictive model checking to perform causal inference. We demonstrate the deconfounder on real-world data and simulation studies, and describe the theoretical requirements for the deconfounder to provide unbiased causal estimates.

This is joint work with Yixin Wang. [*] https://www.tandfonline.com/doi/full/10.1080/01621459.2019.1686987

Biography: David Blei is a Professor of Statistics and Computer Science at Columbia University, and a member of the Columbia Data Science Institute. He studies probabilistic machine learning, including its theory, algorithms, and application. David has received several awards for his research, including a Sloan Fellowship (2010), Office of Naval Research Young Investigator Award (2011), Presidential Early Career Award for Scientists and Engineers (2011), Blavatnik Faculty Award (2013), ACM-Infosys Foundation Award (2013), a Guggenheim fellowship (2017), and a Simons Investigator Award (2019). He is the co-editor-in-chief of the Journal of Machine Learning Research. He is a fellow of the ACM and the IMS.

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Workshop / Seminar Thu, 30 Jan 2020 10:19:09 -0500 2020-02-07T10:00:00-05:00 2020-02-07T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar David Blei
MFG Research-Smart Manufacturing Seminar - Human-Robot Collaboration: Current Status and Future Trends (February 7, 2020 11:00am) https://events.umich.edu/event/72189 72189-17955062@events.umich.edu Event Begins: Friday, February 7, 2020 11:00am
Location: Chrysler Center
Organized By: Integrative Systems + Design

Abstract
Human-robot collaboration has attracted increasing attention, both in academia and in industry. For example, in human-robot collaborative assembly, robots are often required to dynamically change their pre-planned tasks to collaborate with human operators in a shared workspace. However, the robots used today are controlled by pre-generated rigid codes that cannot support effective human-robot collaboration. In response to this need, multi-modal yet symbiotic communication and control methods have been developed. These methods include voice processing, gesture recognition, haptic interaction, and brainwave perception. Deep learning is used for classification, recognition and context awareness identification. Within this context, this seminar provides an overview of the current status of human-robot collaboration including its classification, definition and characteristics. At the end of the seminar, remaining challenges and future research directions will be highlighted.

Speaker Bio
Lihui Wang is a Chair Professor of Sustainable Manufacturing at KTH Royal Institute of Technology, Sweden. His research interests are focused on cyber-physical systems, human-robot collaboration, real-time monitoring and control, predictive maintenance, adaptive and sustainable manufacturing systems. Professor Wang is actively engaged in various professional activities. He is the Editor-in-Chief of Robotics and Computer-Integrated Manufacturing, Editor-in-Chief of International Journal of Manufacturing Research, and Editor-in-Chief of Journal of Manufacturing Systems. He has published 9 books and authored in excess of 500 scientific publications. Professor Wang is a Fellow of Canadian Academy of Engineering, CIRP, SME and ASME, the President-Elect of North American Manufacturing Research Institution of SME, and the Chairman of Swedish Production Academy.

Co-organized by:
Judy Jin (Program Director, ISD Manufacturing; Professor IOE)
Chinedum Okwudire (Associate Chair, ISD; Associate Professor, ME)

Contact: Kathy Bishar (kbishar@umich.edu)

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Workshop / Seminar Wed, 29 Jan 2020 08:17:52 -0500 2020-02-07T11:00:00-05:00 2020-02-07T12:00:00-05:00 Chrysler Center Integrative Systems + Design Workshop / Seminar Lihui Wang
Economics at Work (February 7, 2020 1:00pm) https://events.umich.edu/event/70947 70947-17760216@events.umich.edu Event Begins: Friday, February 7, 2020 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Thu, 09 Jan 2020 10:59:24 -0500 2020-02-07T13:00:00-05:00 2020-02-07T14:10:00-05:00 Lorch Hall Department of Economics Workshop / Seminar Economics
Department of Computational Medicine & Bioinformatics (DCMB) Weekly Seminar (February 12, 2020 4:00pm) https://events.umich.edu/event/72535 72535-18015945@events.umich.edu Event Begins: Wednesday, February 12, 2020 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract:
Normal mechanical function of the heart requires that ATP be continuously synthesized at a hydrolysis potential of roughly -60 kJ mol-1. Yet in both the aging and diseased heart the relationships between cardiac work rate and concentrations of ATP, ADP, and inorganic phosphate are altered. Important outstanding questions are: To what extent do changes in metabolite concentrations that occur in aging and heart disease affect metabolic/molecular processes in the myocardium? How are systolic and diastolic functions affected by changes in metabolite concentrations? Does metabolic energy supply represent a limiting factor in determining physiological maximal cardiac power output and exercise capacity? Does the derangement of cardiac energetics that occurs with heart failure cause exercise intolerance?

To answer these questions, we have developed a multi-physics multi-scale model of cardiac energy metabolism and cardiac mechanics that simulates the dependence of myocardial ATP demand on muscle dynamics and the dependence of muscle dynamics on cardiac energetics. Model simulations predict that the maximal rate at which ATP can be synthesized at free energies necessary to drive physiological mechanical function determine maximal heart rate, cardiac output, and cardiac power output in exercise. Furthermore, we find that reductions in cytoplasmic adenine nucleotide, creatine, and phosphate pools that occur with aging impair the myocardial capacity to synthesize ATP at physiological free energy levels, and that the resulting changes to myocardial energetic status play a causal role in contributing to reductions in maximal cardiac power output with aging. Finally, model predictions reveal that reductions in cytoplasmic metabolite pools contribute to energetic dysfunction in heart failure, which in turn contributes to causing systolic dysfunction in heart failure.

BlueJeans Livestream Link: https://primetime.bluejeans.com/a2m/live-event/rbuvycdc

3:45 p.m. - Light Refreshments served in Forum Hall Atrium
4:00 p.m. - Lecture in Forum Hall

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Lecture / Discussion Wed, 05 Feb 2020 08:41:29 -0500 2020-02-12T16:00:00-05:00 2020-02-12T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Revealing Principles of Subcellular RNA Localization (February 13, 2020 2:00pm) https://events.umich.edu/event/70912 70912-17735217@events.umich.edu Event Begins: Thursday, February 13, 2020 2:00pm
Location: Palmer Commons
Organized By: Department of Molecular, Cellular, and Developmental Biology

Faculty Candidate
Host: A. Wierzbicki and the Life Sciences Institute

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Workshop / Seminar Tue, 28 Jan 2020 11:22:53 -0500 2020-02-13T14:00:00-05:00 2020-02-13T15:00:00-05:00 Palmer Commons Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB initials and yellow microscope on blue background
Distinguished Alumni Speaker Series: Earl Lawrence, Statistical Sciences, Los Alamos National Laboratory (February 14, 2020 10:00am) https://events.umich.edu/event/69918 69918-17483050@events.umich.edu Event Begins: Friday, February 14, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract:
Inference with computationally expensive physics models is a big part of statistics at Los Alamos National Laboratory. The first part of that talk will cover some well-known background on the statistical approach computer experiments. This will take place in the context of ongoing work for ChemCam, an instrument on the Mars rover Curiosity whose goal is to determine whether Mars ever had conditions that could have supported microbial life. ChemCam uses laser-induced breakdown spectroscopy to analyze the chemical composition of Martian soil and rocks. Our goal is to use the resulting spectra and a LANL-developed predictive model to estimate the elemental abundances from surface samples. The second part of the talk will cover new work to address computer experiments from exascale supercomputers. The next generation of supercomputers are expected to have I/O limitations relative to their computing ability: they will simulate more than they can save. This requires changes to our usual post-hoc analysis scheme. To address this, we are developing approaches to in situ statistical inference, statistical modeling that gets done inside simulations as they are running. Our early work considers modeling extremes for climate and space weather.

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Workshop / Seminar Wed, 05 Feb 2020 14:37:54 -0500 2020-02-14T10:00:00-05:00 2020-02-14T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Earl Lawrence
MCIRCC Re-Imagining Critical Care Seminar Series (February 17, 2020 3:00pm) https://events.umich.edu/event/71948 71948-17903306@events.umich.edu Event Begins: Monday, February 17, 2020 3:00pm
Location: North Campus Research Complex Building 10
Organized By: Michigan Center for Integrative Research in Critical Care (MCIRCC)

“Innovation Fundamentals & Opportunities in Critical Care Biomarker Discovery”

Frederick Korley MD, PhD is an Associate Professor of Emergency Medicine.

Dr. Korley's research activities involve translation of novel diagnostics to inform clinically rational, timely, and cost-effective diagnosis of cardiac and brain injury in the emergency department. The goal of his traumatic brain injury work is to improve the acute care diagnosis, risk-stratification and treatment of TBI by identifying distinct molecular subtypes of TBI that will allow for targeted treatment and improved outcomes.

DETAILS & REGISTRATION:
http://bit.ly/FrederickKorley

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Workshop / Seminar Thu, 23 Jan 2020 12:02:33 -0500 2020-02-17T15:00:00-05:00 2020-02-17T16:00:00-05:00 North Campus Research Complex Building 10 Michigan Center for Integrative Research in Critical Care (MCIRCC) Workshop / Seminar MCIRCC Re-Imagining Critical Care Seminar Series with Dr. Frederick K. Korley Flyer
Genetics Training Program / CMB Short Course (630) (February 18, 2020 3:00pm) https://events.umich.edu/event/72320 72320-17974673@events.umich.edu Event Begins: Tuesday, February 18, 2020 3:00pm
Location: Medical Science Unit II
Organized By: Department of Human Genetics

Welcome to the Exciting World of Tandem and Interspersed DNA Repeat Elements
Presented By Jayakrishnan Nandakumar, Ph.D.
Associate Professor
Department of Molecular, Cellular, and Developmental Biology University of Michigan Medical School
Tuesday, February 18, 2020
3:00 p.m.
West Lecture Hall, Med Sci II

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Lecture / Discussion Fri, 31 Jan 2020 13:25:19 -0500 2020-02-18T15:00:00-05:00 2020-02-18T16:00:00-05:00 Medical Science Unit II Department of Human Genetics Lecture / Discussion Nandakumar GTP / CMB Short Course Flyer
DS/CSS Seminar Series: Julia Mendelsohn (February 20, 2020 12:00pm) https://events.umich.edu/event/72978 72978-18120897@events.umich.edu Event Begins: Thursday, February 20, 2020 12:00pm
Location: North Quad
Organized By: School of Information

PhD candidate Julia Mendelsohn will discuss the creation of a computational linguistic framework for analyzing dehumanizing language and the application of that framework to discussions of LGBTQ people in the New York Times from 1986 to 2015.

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Workshop / Seminar Mon, 17 Feb 2020 14:59:28 -0500 2020-02-20T12:00:00-05:00 2020-02-20T13:00:00-05:00 North Quad School of Information Workshop / Seminar Julia Mendelsohn
Microfluidics Seminar: Dr. Xufeng Xue (February 20, 2020 12:00pm) https://events.umich.edu/event/73026 73026-18129602@events.umich.edu Event Begins: Thursday, February 20, 2020 12:00pm
Location: Pierpont Commons
Organized By: Biomedical Engineering

Neurulation is a key embryonic developmental process that gives rise to neural tube (NT), the precursor structure that eventually develops into the central nervous system (CNS). Understanding the molecular mechanisms and morphogenetic events underlying human neurulation is important for the prevention and treatment of neural tube defects (NTDs) and neurodevelopmental disorders. However, animal models are limited in revealing many fundamental aspects of neurulation that are unique to human CNS development. Furthermore, the technical difficulty and ethical constraint in accessing neurulation-stage human embryos have significantly limited experimental investigations of early human CNS development.
I leveraged the developmental potential and self-organizing property of human pluripotent stem cells (hPSCs) in conjunction with 2D and 3D bioengineering tools to achieve the development of spatially patterned multicellular tissues that mimic certain aspects of human neurulation, including neuroectoderm patterning and dorsal-ventral (DV) patterning of NT.
In the first section, I report a micropatterned hPSC-based neuroectoderm model, wherein pre-patterned geometrical confinement induces emergent patterning of neuroepithelial (NE) and neural plate border (NPB) cells, mimicking neuroectoderm patterning during early neurulation. My data support the hypothesis that in this hPS cell-based neuroectoderm patterning model, two tissue-scale morphogenetic signals, cell shape and cytoskeletal contractile force, instruct NE / NPB patterning via BMP-SMAD signaling. This work provides evidence of tissue mechanics-guided neuroectoderm patterning and establishes a tractable model to study signaling crosstalk involving both biophysical and biochemical determinants in neuroectoderm patterning.
In the second section, I report a human NT development model, in which NT-like tissues, termed NE cysts, are generated in a bioengineered neurogenic environment through self-organization of hPSCs. DV patterning of NE cysts is achieved using retinoic acid and/or Sonic Hedgehog, featuring sequential emergence of the ventral floor plate, p3 and pMN domains in discrete, adjacent regions and dorsal territory that is progressively restricted to the opposite dorsal pole.

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Lecture / Discussion Tue, 18 Feb 2020 08:58:46 -0500 2020-02-20T12:00:00-05:00 2020-02-20T13:00:00-05:00 Pierpont Commons Biomedical Engineering Lecture / Discussion BME Logo
BME 500: Ruixuan Gao (February 20, 2020 4:00pm) https://events.umich.edu/event/70421 70421-17594473@events.umich.edu Event Begins: Thursday, February 20, 2020 4:00pm
Location: Electrical Engineering and Computer Science Building
Organized By: Biomedical Engineering

Investigation of the molecular basis of a complex biological system, such as the brain, can lead to fundamental understanding of its composition and function, and to a new strategy to repair it. Such investigation, however, requires a tool that can capture biological structures and their molecular constituents across multiple orders of magnitude—from nanometers to centimeters—in length. Electron microscopy offers nanoscopic resolution but lacks molecular information to differentiate endogenous biomolecules as well as imaging speed to cover millimeter-scale specimens. Light microscopy provides molecular contrast but is limited by optical diffraction and the tradeoff between imaging speed and photobleaching.

In this talk, I will first introduce an optical imaging pipeline named expansion lattice light-sheet microscopy (ExLLSM) and its application to multiplexed, volumetric imaging of molecular constituents in cells and intact tissues. Using ExLLSM, our study has revealed molecular-specific structures of organelles, synapses, myelin sheaths, and neurites in rodent and insect brains at ∼60 by 60 by 90 nm effective resolution across dimensions that span millimeters. Next, I will present two recently developed methods that further extend the resolution and throughput of ExLLSM: (1) a non-radical hydrogel chemistry that forms a homogenous polymer network and physically separates biomolecules or fluorescent labels up to 40-fold linearly, and (2) a multi-modal optical microscopy that enables rapid, high-resolution imaging of both expanded and live tissues. Lastly, I will discuss the significance of these imaging methods in the context of microanatomy and functional omics.

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Lecture / Discussion Thu, 13 Feb 2020 10:34:18 -0500 2020-02-20T16:00:00-05:00 2020-02-20T17:00:00-05:00 Electrical Engineering and Computer Science Building Biomedical Engineering Lecture / Discussion BME Logo
Statistics Department Seminar Series: Bhaswar Bhattacharya, Assistant Professor, Department of Statistics, The Wharton School, University of Pennsylvania (February 21, 2020 10:00am) https://events.umich.edu/event/69919 69919-17483051@events.umich.edu Event Begins: Friday, February 21, 2020 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Two of the fundamental problems in non-parametric statistical inference are goodness-of-fit and two-sample testing. These two problems have been extensively studied and several multivariate tests have been proposed over the last thirty years, many of which are based on geometric graphs. These include, among several others, the celebrated Friedman-Rafsky two-sample test based on the minimal spanning tree and the K-nearest neighbor graphs, and the Bickel-Breiman spacings tests for goodness-of-fit. These tests are asymptotically distribution-free, universally consistent, and computationally efficient (both in sample size and in dimension), making them particularly attractive for modern statistical applications.

In this talk, we will derive the detection thresholds and limiting local power of these tests, thus providing a way to compare and justify the performance of these tests in various applications. Several interesting properties emerge, such as a curious phase transition in dimension 8, and a remarkable blessing of dimensionality in detecting scale changes.

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Workshop / Seminar Fri, 31 Jan 2020 16:34:15 -0500 2020-02-21T10:00:00-05:00 2020-02-21T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Bhattacharya