Happening @ Michigan https://events.umich.edu/list/rss RSS Feed for Happening @ Michigan Events at the University of Michigan. Economic Theory: Signaling with Private Monitoring (Joint work with Aaron Kolb) (September 29, 2020 1:00pm) https://events.umich.edu/event/81675 81675-20941459@events.umich.edu Event Begins: Tuesday, September 29, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract
We study dynamic signaling when the informed party does not observe the signals generated by her actions. A long-run player signals her type continuously over time to a myopic second player who privately monitors her behavior; in turn, the myopic player transmits his private inferences back through an imperfect public signal of his actions. Preferences are linear-quadratic and the information structure is Gaussian. We construct linear Markov equilibria using belief states up to the long-run player’s second-order belief. Because of the private monitoring, this state is an explicit function of the long-run player’s past play. A novel separation effect then emerges through this second-order belief channel, altering the traditional signaling that arises when beliefs are public. Applications to models of leadership, reputation, and trading are examined.

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Workshop / Seminar Wed, 03 Feb 2021 11:30:02 -0500 2020-09-29T13:00:00-04:00 2020-09-29T14:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIPSE Seminar | Relativistic Nanophotonics: Creating Extreme Plasma Conditions and Fields with Ultrafast Lasers (September 30, 2020 3:30pm) https://events.umich.edu/event/76451 76451-19717148@events.umich.edu Event Begins: Wednesday, September 30, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

Abstract:
Ultra-high-energy-density (UHED) matter (>108 J cm-3, >109 bar) is encountered in the center of stars but is difficult to create in the lab. We show that irradiation of high aspect-ratio aligned nanowire arrays with ultra-high contrast Joule-level fs laser pulses provides nearly complete absorption and enhanced light penetration into near-solid density targets, and allows volumetric heating into the UHED regime. Using ALEPH (Advance Laser for Extreme Photonics), a PW laser at CSU, we demonstrate that fs laser pulses of relativistic intensity volumetrically heat near-solid density plasmas to multi-keV temperatures, with pressures surpassed in the lab only in the hotspot of fusion plasmas. The physics of relativistic laser pulse interactions with nanostructures and promising applications will be reviewed. Electron densities >100x that of the critical density are achieved. Extraordinarily high degrees of ionization (e.g., Au+72) occurs at solid densities using laser pulses of <10 J, producing return currents through the nanowires that create giga-Gauss magnetic fields. The large electron density and plasma volume produce 20% energy conversion into ps x-ray pulses. Acceleration of deuterons from nanowire arrays to multi-MeV resulted in quasi-monochromatic fusion neutron production 500x that of irradiating flat sold targets. 3-D PIC simulations of relativistic laser pulse interactions with nanostructures will be discussed.

About the Speaker:
Dr. Jorge Rocca is a University Distinguished Professor in the Electrical and Computer Engineering and Physics Departments at Colorado State University. His research interests are in the physics and development of compact X-ray lasers and their applications; the development of high power lasers, and the study of high power laser interactions with matter. His group is known for the development of the first bright table-top soft X-ray lasers, and their applications to nanotechnology and the diagnostics of dense plasmas. His group has developed a multi-Hz PW-class laser, and kW-level average power, high pulse energy picosecond solid state lasers. Prof. Rocca has 270 peer review journal papers. He received the Arthur L. Schawlow Prize in Laser Science from the APS, and the Willis E. Lamb Award for Laser Science and Quantum Optics. He is Fellow of APS, OSA, and IEEE. He received an IEEE LEOS Distinguished Lecturer Award. Early in his career, he was a National Science Foundation Presidential Young Investigator.

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Livestream / Virtual Tue, 01 Sep 2020 10:31:50 -0400 2020-09-30T15:30:00-04:00 2020-09-30T16:30:00-04:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Livestream / Virtual Prof. Jorge Rocca
DCMB / CCMB Weekly Virtual Seminar - Xiaotian Zhang, Ph.D. (September 30, 2020 4:00pm) https://events.umich.edu/event/77549 77549-19883820@events.umich.edu Event Begins: Wednesday, September 30, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The human genome is organized into small compartments to allow for the proper gene expression regulation in the physiological process. With the advance of next-generation sequencing and imaging technologies, we can now investigate how the genome is folded into 3D space and how the 3D genomic organization regulates gene expression in development and disease. Currently, most of the studies are focusing on CTCF and cohesion complex which partner together to facilitate the formation of topological associated domains (TAD). The presenter will mainly discuss his recently published work on the DNA methylation -3D genomics cross-talk. Unpublished work on the 3D genomics in AML will be discussed as well.

Short bio: Xiaotian Zhang obtained his Ph.D. at Baylor College of Medicine with Dr. Margaret Goodell on the role of DNA methylation synergy in leukemia development. He was previously the Van Andel special postdoc fellow in Gerd Pfeifer lab working on the 3D genomics in normal hematopoietic stem cell and leukemia. He is now a Research track faculty (Research Investigator) in Pathology Department under Tomek Cierpicki working on the HOXA regulation in leukemia development. Xiaotian's research focuses on the epigenetic regulation of key pathogenic genes in leukemia, particularly on high order chromatin structure in disease. He published on Nature Genetics, Molecular Cell and Blood as the first author and corresponding authors.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Tue, 22 Sep 2020 09:31:31 -0400 2020-09-30T16:00:00-04:00 2020-09-30T17:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Xiaotian Zhang, Ph.D., Research Investigator in the Department of Pathology at the University of Michigan
How shall we drug the MAPK pathway in Head and Neck Cancer? From exceptional responses to Immunogenomics (October 1, 2020 12:00pm) https://events.umich.edu/event/77492 77492-19875790@events.umich.edu Event Begins: Thursday, October 1, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Vivian Wai Yan Lui, PhD
Associate Professor and Deputy Chief
(Cancer Biology and Experimental Therapeutics)
Pharmacogenomics Working Group,
National Society of Genetic Counselors (NSGC), USA
Joint CUHK-NTEC Clinical Research Ethics Committee, CUHK
SBS College Coordinator, United College, CUHK
School of Biomedical Sciences
Faculty of Medicine
The Chinese University of Hong Kong

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Presentation Mon, 21 Sep 2020 11:49:50 -0400 2020-10-01T12:00:00-04:00 2020-10-01T13:00:00-04:00 Off Campus Location Office of Research School of Dentistry Presentation seminar flyer
BME Seminar Series: Gautam Parthasarathy (October 1, 2020 4:00pm) https://events.umich.edu/event/75905 75905-19623823@events.umich.edu Event Begins: Thursday, October 1, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 13:56:48 -0400 2020-10-01T16:00:00-04:00 2020-10-01T17:00:00-04:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Statistics Department Seminar Series: Laura Kubatko, Professor, Departments of Statistics and Evolution, Ecology, and Organismal Biology, The Ohio State University (October 2, 2020 10:00am) https://events.umich.edu/event/77451 77451-19854034@events.umich.edu Event Begins: Friday, October 2, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: The advent of rapid and inexpensive DNA sequencing technologies has necessitated the development of computationally efficient methods for analyzing sequence data for many genes simultaneously in an evolutionary framework. The coalescent process is the most commonly used model for linking the underlying genealogies of individual genes with the global species-level phylogenetic tree, but inference under the coalescent model is computationally daunting in the typical inference frameworks (e.g., the likelihood and Bayesian frameworks) due to the dimensionality of the space of both gene trees and species trees. By viewing the data arising under the phylogenetic coalescent model as a collection of site patterns, the algebraic structure associated with the probability distribution on the site patterns can be used to develop computationally efficient methods for inference via phylogenetic invariants. In this talk, I will describe how identifiability results for four-taxon species trees based on site pattern probabilities can be used to build a quartet-based inference algorithm for trees of arbitrary size. I will also show how a composite likelihood approach based on quartets can be developed to obtain estimators of the branch lengths within the tree that are consistent and asymptotically normal. I will demonstrate the performance of the methods by applying them to both simulated and empirical data. Because these methods are derived in a fully model-based framework (i.e., the coalescent process is used to model the relationship between gene trees and the species tree, and standard nucleotide substitution models (GTR+I+G and all submodels) are used for sequence-level evolution), they are promising approaches for computationally efficient, model-based inference for the large-scale sequence data available today.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow.

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Workshop / Seminar Fri, 18 Sep 2020 15:26:22 -0400 2020-10-02T10:00:00-04:00 2020-10-02T11:00:00-04:00 Off Campus Location Department of Statistics Workshop / Seminar Laura Kubatko
Biophysics Virtual Seminar Series (October 2, 2020 12:00pm) https://events.umich.edu/event/77871 77871-19939555@events.umich.edu Event Begins: Friday, October 2, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

*Please see below for link to join the Zoom event. Passcode: Biophysics*

The Biophysics Virtual Seminar Series Presents:

Nirupama Sumangala - Biophysics Ph.D. Candidate (Ramamoorthy Group)

"Lipid Membrane Plays an Important Role for Facilitating Electron Transfer in Cytochrome P450"

Abstract: Cytochrome P450s (CYP450s) are a ubiquitous superfamily of enzymes that play a vital role in the metabolism of many exogenous and endogenous substrates including over 70% of the drugs on the market. For the catalytic reaction, CYP450 requires two electrons to be subsequently delivered, with the first one coming from cytochrome P450 reductase (CPR) and the second one from either CPR or cytochrome b5 (cytb5). We are interested in understanding the role of membrane in mediating the electron transfer from redox partners to CYP450. Our findings reveal that the lipid membrane is crucial to mediate a productive CYP450-CPR complex for electron transfer. Our data emphasizes the importance of studying the structure, dynamics and kinetics of CYP450 metabolon in a biologically relevant membrane mimetic system.

Keanu Guardiola Flores - Biophysics Ph.D. Candidate (Wood Group)

"Drug Effects on *Enterococcus Faecalis* Biofilms: Growth, Topology, and Population Dynamics"

Abstract: The emergence of antibiotic resistance poses a growing threat to public health and increasingly limits our ability to treat and control infections. Recently, researchers have shifted their focus to length scales where ecological and evolutionary dynamics of bacterial communities highlight new approaches for slowing resistance with currently available drugs. By combining confocal microscopy with simple mathematical models I will show how antibiotics shape the composition of biofilms as well as their spatial architecture at the single-cell level. Our results suggest that in spatially structured populations, which may more accurately reflect natural bacterial communities, the selection of resistance is not a simple result of homogenous selections but depends critically on the spatial arrangement of cells.

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Livestream / Virtual Tue, 29 Sep 2020 08:47:28 -0400 2020-10-02T12:00:00-04:00 2020-10-02T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual
MCDB Virtual Seminar: Neural basis of host seeking in skin-penetrating nematodes (October 2, 2020 12:00pm) https://events.umich.edu/event/77385 77385-19846072@events.umich.edu Event Begins: Friday, October 2, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Monica Dus

Seminar: 12 pm - 1 pm
Q&A: 1:15 pm-2:00 pm

https://umich.zoom.us/j/92994136746

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Workshop / Seminar Fri, 25 Sep 2020 14:19:06 -0400 2020-10-02T12:00:00-04:00 2020-10-02T14:00:00-04:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Elissa Hallem
Economics at Work (October 2, 2020 1:00pm) https://events.umich.edu/event/78076 78076-19957575@events.umich.edu Event Begins: Friday, October 2, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/k5yhSQDcPPmUupVXA

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Workshop / Seminar Thu, 01 Oct 2020 17:14:11 -0400 2020-10-02T13:00:00-04:00 2020-10-02T14:30:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economic Theory: Robust Monopoly Regulation (Joint work with Eran Shmaya) (October 2, 2020 2:30pm) https://events.umich.edu/event/81676 81676-20941460@events.umich.edu Event Begins: Friday, October 2, 2020 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract
We study the regulation of a monopolistic firm using a non-Bayesian approach. We derive the policy that minimizes the regulator’s worst-case regret, where regret is the difference between the regulator’s complete-information payoff and his realized payoff. When the regulator’s payoff is consumers’ surplus, he imposes a price cap. When his payoff is the total surplus of both consumers and the firm, he offers a capped piece-rate subsidy. For intermediate cases, the regulator uses both a price cap and a capped piece-rate subsidy. The optimal policy balances three goals: giving more surplus to consumers, mitigating underproduction, and mitigating overproduction.

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Workshop / Seminar Wed, 03 Feb 2021 11:32:35 -0500 2020-10-02T14:30:00-04:00 2020-10-02T15:50:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Cognitive Science Seminar Series (October 5, 2020 2:30pm) https://events.umich.edu/event/77842 77842-19933640@events.umich.edu Event Begins: Monday, October 5, 2020 2:30pm
Location: Off Campus Location
Organized By: Weinberg Institute for Cognitive Science

Research fellow Elisa Felsche (U-M Psychology) will give a talk on "The origins of inference: A hierarchical Bayesian modelling approach to imitation and abstraction in children and primates."

NOTE: If you would like to attend this meeting, please send an email to cogsi-seminar@umich.edu to receive the passcode.

ABSTRACT

Humans have an immense behavioural and cognitive repertoire that has been shaped by cumulative cultural evolution. In my PhD project I investigated two cognitive abilities that crucially enlarge the efficiency of skill and knowledge acquisition: 1) the capability for abstraction that enables powerful generalization of information to make wide ranging predictions in new situations and 2) the ability to imitate others which allows the quick and low-risk adoption of new behavioural strategies. Despite decades of accumulating data in both domains, it is still debated to what extent other species share these abilities and how they develop in humans. Solving these persisting disagreements requires an alteration of how data are generated and analysed.
In my dissertation project, I introduced the approach of hierarchical Bayesian modelling to the field of comparative psychology to investigate abstract rule formation and action copying in capuchin monkeys, chimpanzees (only abstract rule formation) and children. In the first two studies participants had to use sampled evidence to infer abstract rules about the item distributions in containers and efficiently guide behaviour in novel test situations. In a third study, we investigated children's and capuchin monkeys' ability to integrate causal and social information when copying a goal-directed behaviour. Whereas children’s performance was mostly in line with the predictions of the computational models, showing that they are capable of abstraction and consider causal information when imitating, capuchin monkeys performed in all experiments at chance and chimpanzees showed some understanding of abstract rules.

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Workshop / Seminar Fri, 02 Oct 2020 15:51:03 -0400 2020-10-05T14:30:00-04:00 2020-10-05T15:30:00-04:00 Off Campus Location Weinberg Institute for Cognitive Science Workshop / Seminar
Honors Seminar Series: Julie Boland (October 7, 2020 2:00pm) https://events.umich.edu/event/76512 76512-19719173@events.umich.edu Event Begins: Wednesday, October 7, 2020 2:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

Conversation usually seems effortless, but the rapid transitions between speakers entail multi-tasking that challenges our understanding of attention and working memory. In my lab, we've been conducting experiments to better understand this puzzle and I will describe some of our recent results

Please join us by registering for this event here: https://myumi.ch/0W1Op

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Workshop / Seminar Tue, 29 Sep 2020 14:18:04 -0400 2020-10-07T14:00:00-04:00 2020-10-07T15:00:00-04:00 Off Campus Location LSA Honors Program Workshop / Seminar Photo of Julie Boland
DCMB / CCMB Weekly Seminar (October 7, 2020 4:00pm) https://events.umich.edu/event/78232 78232-19996937@events.umich.edu Event Begins: Wednesday, October 7, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The chromosomes of the human genome are organized in three-dimensions by compartmentalizing the cell nucleus and different genomic loci also interact with each other. However, the principles underlying such nuclear genome organization and its functional impact remain poorly understood. In this talk, I will introduce some of our recent work in developing machine learning methods by utilizing whole-genome mapping data to study the higher-order genome organization. Our methods reveal the spatial localization of chromosome regions and exploit chromatin interactome patterns within the cell nucleus in different cellular conditions, across mammalian species, and also in single-cell resolution. We hope that these algorithms will provide new insights into the principles of nuclear spatial organization.

Bio: Jian Ma is an Associate Professor in the Computational Biology Department within the School of Computer Science at Carnegie Mellon University. He was previously on the faculty of the University of Illinois at Urbana-Champaign. His lab develops algorithms to study the structure and function of the human genome with a focus on nuclear organization, gene regulation, comparative genomics, and single cell biology. He received several awards, including an NSF CAREER award and a Guggenheim Fellowship. He is the Contact PI of a UM1 Center project in the NIH 4D Nucleome Program (Phase 2; 2020-2025). https://www.cs.cmu.edu/~jianma/

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 06 Oct 2020 12:47:39 -0400 2020-10-07T16:00:00-04:00 2020-10-07T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Engineering an immunological niche for early detection of immune dysfunction (October 8, 2020 12:00pm) https://events.umich.edu/event/77515 77515-19877791@events.umich.edu Event Begins: Thursday, October 8, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Lonnie Shea, PhD
William and Valerie Hall Chair
Steven A. Goldstein Collegiate Professor
Biomedical Engineering
University of Michigan

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Presentation Mon, 21 Sep 2020 13:40:07 -0400 2020-10-08T12:00:00-04:00 2020-10-08T13:00:00-04:00 Off Campus Location Office of Research School of Dentistry Presentation flyer
BME Seminar Series: Nathan Price (October 8, 2020 4:00pm) https://events.umich.edu/event/75906 75906-19623824@events.umich.edu Event Begins: Thursday, October 8, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:01:08 -0400 2020-10-08T16:00:00-04:00 2020-10-08T17:00:00-04:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Biophysics Virtual Seminar Series (October 9, 2020 12:00pm) https://events.umich.edu/event/76961 76961-19782523@events.umich.edu Event Begins: Friday, October 9, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

*Please see below for the link to join the Zoom livestream*

The Biophysics Virtual Seminar Series Presents:

Hong Qian - Olga Jung Wan Endowed Professor of Applied Mathematics, Department of Applied Mathematics, University of Washington

“A Mathematical Principle of Stochastic Chemical Kinetics and
Emergent Chemical Thermodynamics that Applies to Living Cells”

Abstract: In contrast to featureless point masses in Mechanics, a macromolecule in biochemistry has a large number of internal degrees of freedom in terms of atoms. The behavior of even a single protein in an aqueous environment, is often so complex that the mathematical representation of biochemical kinetics has to be statistical. In this talk, I present a stochastic formulation of general chemical reaction systems, with *N* species and *M* stochastic elementary reactions in solution and show how J. W. Gibbs’ macroscopic equilibrium chemical thermodynamics can be derived as a mathematical result, with an entropic force as its center piece. Our theory is actually applicable to mesoscopic open chemical systems with a chemostat, such as a single living cell. I then discuss the application of this theory to understand the notion of non-genetic phenotype switching, in terms of a landscape, in cell differentiation and cancer heterogeneity.

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Livestream / Virtual Fri, 09 Oct 2020 10:27:08 -0400 2020-10-09T12:00:00-04:00 2020-10-09T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual Zoom Passcode: Biophysics
MCDB Virtual Seminar: Structural Insights into TRP channels gating (October 9, 2020 12:00pm) https://events.umich.edu/event/77386 77386-19846073@events.umich.edu Event Begins: Friday, October 9, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Randy Stockbridge

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Workshop / Seminar Thu, 08 Oct 2020 16:06:20 -0400 2020-10-09T12:00:00-04:00 2020-10-09T14:00:00-04:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB-initials-and-microscope-in yellow on a blue square
Economic Theory: Scoring Strategic Agents (October 9, 2020 2:30pm) https://events.umich.edu/event/81677 81677-20941461@events.umich.edu Event Begins: Friday, October 9, 2020 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract
I introduce a model of predictive scoring. A receiver wants to predict a sender’s quality. An intermediary observes multiple features of the sender and aggregates them into a score. Based on the score, the receiver takes a decision. The sender wants the most favorable decision, and she can distort each feature at a privately known cost. I characterize the most accurate scoring rule. This rule underweights some features to deter sender distortion, and overweights other features so that the score is correct on average. The receiver prefers this score to full disclosure because the aggregated information mitigates his commitment problem.

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Workshop / Seminar Wed, 03 Feb 2021 11:42:44 -0500 2020-10-09T14:30:00-04:00 2020-10-09T15:50:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Hands-on Workshop: Creating a Hybrid Simulation System Using the Simple Run Time Infrastructure Software (October 9, 2020 4:00pm) https://events.umich.edu/event/76684 76684-19735053@events.umich.edu Event Begins: Friday, October 9, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Computational Discovery and Engineering

The goal of this hands-on workshop is to introduce the Simple Run-Time Infrastructure software toolkit (SRTI) to the participants, and provide a template project consisting of multiple simulators, each with a specialized purpose, relating to a natural-disaster scenario. It will take place after the feature talks.

The SRTI is a free, open-source solution developed at the University of Michigan, and enables researchers to connect computer programs and simulators written in different languages, to share data during execution, and to design hybrid systems using disparate simulator modules, with a primary goal of being user friendly. This hands-on workshop will explain what the SRTI is, and provide an example on how to use it.

The Java Runtime Environment (JRE) is required to run the SRTI. Please install it prior to the workshop. Refer to icor.engin.umich.edu for more information on supported operating systems and languages. Participants will need to use their own computer systems at home to take part. Basic coding skills in any programming language are required.

Open to the general public. Please register if you wish to participate.

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Workshop / Seminar Thu, 03 Sep 2020 16:10:17 -0400 2020-10-09T16:00:00-04:00 2020-10-09T18:00:00-04:00 Off Campus Location Michigan Institute for Computational Discovery and Engineering Workshop / Seminar Creating a Hybrid Simulation System Using the Simple Run Time Infrastructure Software
Honors Seminar Series: Sara Fitzgerald (October 12, 2020 2:00pm) https://events.umich.edu/event/75960 75960-19629761@events.umich.edu Event Begins: Monday, October 12, 2020 2:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

In 1970, as Michigan prepared to celebrate the 100th anniversary of the admission of women, women faculty at U.S. colleges were exempted from the protections of the major civil rights laws and the U-M admissions office was enforcing a 55:45 quota on male-female admissions to ensure that there would not be an “overbalance” of women in the freshman class. But a small group of Ann Arbor women developed a strategy to unleash the power of the federal government to demand change at U-M by threatening to withhold millions of dollars in federal contracts. The settlement provided the model for resolving similar complaints at dozens of other universities in the years immediately before the passage of Title IX. Sara Fitzgerald, then an Honors history major, covered the controversy for The Michigan Daily, and a half-century later, reflects on how that time on campus shaped her own career aspirations and writing interests.

Author of "Conquering Heroines", and Honors alumna, Sara Fitzgerald is a former editor and new-media developer for the Washington Post and was the first woman to serve as editor-in-chief of the Michigan Daily. She is the author of Elly Peterson: “Mother” of the Moderates (University of Michigan Press, 2012) and The Poet’s Girl (Thought Catalog Books, 2020).

Please register for this event here: https://myumi.ch/0W1Op

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Workshop / Seminar Tue, 29 Sep 2020 14:26:32 -0400 2020-10-12T14:00:00-04:00 2020-10-12T15:00:00-04:00 Off Campus Location LSA Honors Program Workshop / Seminar Photo of Sara Fitzgerald
The Evolution of Basketball with Data Science (October 12, 2020 4:00pm) https://events.umich.edu/event/78271 78271-20002854@events.umich.edu Event Begins: Monday, October 12, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

For the last couple of decades, most industries have grown to take advantage of the information gained from data collection. As that happened, professional sports teams started to catch on. Baseball took the lead thanks to the amount of data collected over the years, which dates to the 1800s, but a lot of other professional sports followed and put more attention to their data collection. With technological advancements, particularly high-speed cameras, storage capacities and image recognition, more dynamic sports started to collect richer and richer data. The insights derived from this data started shifting the way the game is played and the way players are evaluated. This talk will take you through the evolution of data science in basketball and give examples of how data is shifting the way teams make decisions on and off the court.

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Presentation Wed, 07 Oct 2020 09:55:02 -0400 2020-10-12T16:00:00-04:00 2020-10-12T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation https://umich.zoom.us/j/94496488704
How Lean Culture is Fighting Against the Coronavirus (October 12, 2020 4:30pm) https://events.umich.edu/event/78063 78063-19957560@events.umich.edu Event Begins: Monday, October 12, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

We’ve all been impacted by the COVID-19 pandemic in different ways. For me, one of the ways was receiving a call to “deploy” to our ventilator manufacturing facility to help make an unprecedented volume of ventilators as fast as possible. The world needed ventilators to fight COVID-19 and we needed to ramp production using our best manufacturing methodologies.Using Lean techniques was once described by one of its founding leaders, Taiichi Ohno, as “looking at the timeline, from the moment the customer gives us an order to the point when we collect the cash. And we are reducing the timeline by reducing the non-value adding wastes.” GE Healthcare has incorporated Lean into its operational fabric just as described in the quote to delivery reliable daily output as well as to take on new manufacturing challenges. In this presentation, I will describe the challenge that COVID-19 presented to our company, to the production process & to the cross-functional group of people involved in supporting production. To tell this story, I will be sharing some basics about Lean Methodologies and how it influenced our approach, communications & the execution of an unprecedented ventilator output. Finally, I will discuss how these same methodologies and approach can be used to positively impact your business, career, or challenge you’re facing.

Passion: My passion is serving the Healthcare community by educating eager learners, utilizing Lean-6 Sigma methodologies & incorporating Advanced Technologies to challenge the status quo & bring about meaningful improvement.

Experience: I’ve been with GE Healthcare for 15 years in a variety of roles from a manufacturing engineer, to a site & national Lean Leader to a multi-state field service director. These roles have including manufacturing, service & commercial elements to them and always included a primary focus on healthcare. Additionally, I have worked within the aviation, energy & financial industries through cross-business projects. With my experience, I was recently called on by GE to help during the COVID-19 response to drive increased output, improved quality & to build a supportive culture in our ventilator manufacturing business. Additionally, I have used this knowledge to start an education & consulting group focused on Lean methodologies called ripple Solutions LLC. My small business has allowed me to expand outside of healthcare & connect with the printing, distribution, university & non-healthcare manufacturing industries.

Education: I have a degree in Industrial Engineering with additional courses in Medical Sciences from University of Michigan, class of 2007. I am a GE Healthcare Operations Management Leadership Program graduate, I’m a certified Black Belt in DMAIC Lean Six Sigma and I’m Green Belt certified in DFSS Six Sigma. I have also received extensive GE Healthcare & Shingijtsu Lean training.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 01 Oct 2020 14:52:38 -0400 2020-10-12T16:30:00-04:00 2020-10-12T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion photo of speaker with event information
DCMB / CCMB Weekly Seminar (October 14, 2020 4:00pm) https://events.umich.edu/event/78234 78234-19996940@events.umich.edu Event Begins: Wednesday, October 14, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Gaussian processes provide flexible non-parametric models of data and we are using them to model temporal and spatial patterns in gene expression. Single-cell omics measurements are destructive and one cannot follow the high-dimensional dynamics of genes across time in one cell. Similarly, the spatial context of cells is often lost or only known with reduced resolution. Computational methods are widely used to infer pseudo-temporal orderings of cells or to infer spatial locations. We show how Gaussian processes (GPs) can be used to model temporal and spatial relationships between genes and cells in these datasets. As examples I will show how we use Bayesian GPLVMs with informative priors to infer pseudo-temporal orderings for single-cell time course data [1] and branching GPs to identify gene-specific bifurcation points across pseudotime [2]. Gene expression data are often summarized as counts and there may be many zero values in the data due to limited sequencing depth. We therefore recently extended these methods to use negative binomial or zero-inflated negative binomial likelihoods and we show that this can lead to much improved performance over standard Gaussian noise models when identifying spatially varying genes from spatial transcriptomics data [3].

[1] Ahmed, S., Rattray, M., & Boukouvalas, A. (2019). GrandPrix: scaling up the Bayesian GPLVM for single-cell data. Bioinformatics, 35(1), 47-54.

[2] Boukouvalas, A., Hensman, J., & Rattray, M. (2018). BGP: identifying gene-specific branching dynamics from single-cell data with a branching Gaussian process. Genome biology, 19(1), 65.

[3] BinTayyash, N., Georgaka, S., John, S. T., Ahmed, S., Boukouvalas, A., Hensman, J., & Rattray, M. (2020). Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments. Bioarxiv https://doi.org/10.1101/2020.07.29.227207

Short bio: Magnus Rattray is Professor of Computational and Systems Biology at the University of Manchester and Director of the Institute for Data Science & AI. He works on the development of methods for machine learning and Bayesian inference with applications to large-scale biological and medical datasets. He has a long-standing interest in longitudinal data analysis and a more recent interest in modelling single-cell, spatial omics and live cell imaging microscopy data. He is a Fellow of the ELLIS Health Programme and the Alan Turing Institute and his research is funded by a Wellcome Trust Investigator Award.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 06 Oct 2020 13:35:21 -0400 2020-10-14T16:00:00-04:00 2020-10-14T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Magnus Rattray, PhD (Professor of Computational and Systems Biology, University of Manchester)
Michael Beauregard Seminar in Macroeconomics: The Global Financial Resource Curse (October 14, 2020 4:00pm) https://events.umich.edu/event/78087 78087-19963473@events.umich.edu Event Begins: Wednesday, October 14, 2020 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Since the late 1990s, the United States has received large capital flows from developing countries - a phenomenon known as the global saving glut - and experienced a productivity growth slowdown. Motivated by these facts, we provide a model connecting international financial integration and global productivity growth. The key feature is that the tradable sector is the engine of growth of the economy. Capital flows from developing countries to the United States boost demand for U.S. non-tradable goods, inducing a reallocation of U.S. economic activity from the tradable sector to the non-tradable one. In turn, lower profits in the tradable sector lead firms to cut back investment in innovation. Since innovation in the United States determines the evolution of the world technological frontier, the result is a drop in global productivity growth. This effect, which we dub the global financial resource curse,
can help explain why the global saving glut has been accompanied by subdued investment and growth, in spite of low global interest rates.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Fri, 02 Oct 2020 08:42:47 -0400 2020-10-14T16:00:00-04:00 2020-10-14T17:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
3D organization of human genome in development and disease – A perspective from 3D genome engineering (October 15, 2020 12:00pm) https://events.umich.edu/event/78431 78431-20044394@events.umich.edu Event Begins: Thursday, October 15, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Xiaotian Zhang, PhD
Research Investigator
Department of Pathology
Tomasz Cierpicki/Jolanta Grembecka lab
University of Michigan

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Lecture / Discussion Mon, 12 Oct 2020 12:04:51 -0400 2020-10-15T12:00:00-04:00 2020-10-15T13:00:00-04:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Zhang
Biophysics Seminar Series (October 16, 2020 12:00pm) https://events.umich.edu/event/77916 77916-19941582@events.umich.edu Event Begins: Friday, October 16, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

*Please see below for the link to join the Zoom event.*

The Biophysics Virtual Seminar Series presents:

Dr. Jamie Cate - Professor of Molecular & Cell Biology, and Chemistry,
University of California - Berkeley

“Selective modulation of human translation: potential for new therapeutics”

ABSTRACT: Small molecules that target the ribosome such as antibiotics generally impact a substantial fraction of the proteome. We recently identified a class of small molecules that bind the human ribosome and selectively stall the translation of a small subset of proteins. I will present biochemical and cell-based experiments, along with structures of human ribosome nascent chain complexes (RNCs) stalled by these compounds, determined by cryo-electron microscopy (cryo-EM). These small molecules bind in the ribosome exit tunnel in a eukaryotic-specific pocket formed by the 28S ribosomal RNA (rRNA) and arrest the translating ribosome through their interactions with the growing polypeptide chain. Intriguingly, a given compound can either inhibit or enhance translation, depending on the sequence of the protein nascent chain. These results begin to reveal how small molecules can be made to control human translation and suggest a new strategy for developing small molecules that selectively inhibit or enhance the production of proteins previously considered “undruggable.”

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Livestream / Virtual Thu, 08 Oct 2020 12:47:14 -0400 2020-10-16T12:00:00-04:00 2020-10-16T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Jamie Cate
MCDB Virtual Seminar: Neural circuit mechanisms and technology for pain and social touch (October 16, 2020 12:00pm) https://events.umich.edu/event/77404 77404-19848066@events.umich.edu Event Begins: Friday, October 16, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Behaar Chawla

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Workshop / Seminar Thu, 08 Oct 2020 16:10:22 -0400 2020-10-16T12:00:00-04:00 2020-10-16T14:00:00-04:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Ishmail with books background
Economic Theory: Selling two identical objects (Joint work with Sushil Bikhchandani) (October 16, 2020 1:00pm) https://events.umich.edu/event/81678 81678-20941462@events.umich.edu Event Begins: Friday, October 16, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract
It is well-known that optimal (i.e., revenue-maximizing) selling mechanisms in multidimensional type spaces may involve randomization. We study mechanisms for selling two identical, indivisible objects to a single buyer. We analyze two settings: (i) decreasing marginal values (DMV) and (ii) increasing marginal values (IMV). Thus, the two marginal values of the buyer are not independent. We obtain sufficient conditions on the distribution of buyer values for the existence of an optimal mechanism that is deterministic.
In the DMV model, we show that under a well-known condition, it is optimal to sell the first unit deterministically. Under the same sufficient condition, a bundling mechanism (which is deterministic) is optimal in the IMV model. Under a stronger sufficient condition, a deterministic mechanism is optimal in the DMV model.
Our results apply to heterogenous objects when there is a specified sequence in which the two objects must be sold.

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Workshop / Seminar Wed, 03 Feb 2021 11:46:18 -0500 2020-10-16T13:00:00-04:00 2020-10-16T14:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economics at Work (October 16, 2020 1:00pm) https://events.umich.edu/event/78077 78077-19957576@events.umich.edu Event Begins: Friday, October 16, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/wAegqGt6tqkWaXdx9

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Workshop / Seminar Thu, 01 Oct 2020 17:18:23 -0400 2020-10-16T13:00:00-04:00 2020-10-16T14:30:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Towards an Artificial Intuition: Conversational Markers of (Anti)Social Dynamics (October 19, 2020 4:00pm) https://events.umich.edu/event/78274 78274-20002858@events.umich.edu Event Begins: Monday, October 19, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Can conversational dynamics—the nature of the back and forth between people—predict outcomes of social interactions? This talk will describe efforts on developing an artificial intuition about ongoing conversations, by modeling the subtle pragmatic and rhetorical choices of the participants.
The resulting framework distills emerging conversational patterns that can point to the nature of the social relation between interlocutors, as well as to the future trajectory of this relation. For example, I will discuss how interactional dynamics can be used to foretell whether an online conversation will stay on track or eventually derail into personal attacks, providing community moderators several hours of prior notice before an anti-social event is likely to occur.
The data and code are available through the Cornell Conversational Analysis Toolkit (ConvoKit): http://convokit.cornell.edu
This talk includes joint work with Jonathan P. Chang, Lucas Dixon, Liye Fu, Yiqing Hua, Dan Jurafsky, Lillian Lee, Jure Leskovec, Vlad Niculae, Chris Potts, Arthur Spirling, Dario Taraborelli, Nithum Thain, and Justine Zhang.

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Presentation Wed, 07 Oct 2020 10:03:41 -0400 2020-10-19T16:00:00-04:00 2020-10-19T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation https://umich.zoom.us/j/95443347994
Tracking A Pandemic: An Analytical View of the COVID-19 Progression and Implications for Business Plans to Re-Engage in the Economy (October 19, 2020 4:30pm) https://events.umich.edu/event/78333 78333-20010773@events.umich.edu Event Begins: Monday, October 19, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

The SARS-CoV-2 virus caused widespread disruption across the globe, affecting literally every aspect of human life. The business environment was not spared in this disruption, as customers, the workforce, workplace environments and supply chains were each turned upside-down, almost overnight. Operating practices needed to be challenged, re-engineered and re-adopted – at the speed of business. That is akin to replacing the aircraft engine while the plane is mid-flight.

The challenge faced by business leaders from the outset of the pandemic, and remains true today, is that objective, analytical information on the state of the virus was and remains woefully inadequate. Further, every organization operating in multiple geographical and political jurisdictions has to navigate different and every-changing rules governing the ability to conduct operations.

In mid-March, I launched an effort to build a repository of critical virus-related information (tests, positives, infections, recoveries, fatalities) at various levels of granularity – world, country, state or province, and metropolitan area. From this, I established a daily reporting mechanism and underlying analyses, designed to equip business leaders, economic and investment advisors and clinicians with insight about the state of the virus spread and underlying trends. My intent was to inform these leaders with actionable intelligence, free of both the fearmongering and denial perspectives that were dominating the general and social media.

These efforts have resulted in my direct engagement with four organizations’ operational planning efforts around the pandemic: two for-profit organizations involved in the manufacture and distribution of critical medical/life sciences products to consumers around the globe, a not-for-profit agency supporting families of critically-ill children and a governmental agency charged with administering a state-wide pandemic response effort. Additionally, I provide daily reports on the state of the virus to an estimated 2,000 clinicians, health organization managers, economists and investment managers.

These lessons provide strong insight for the analytical practitioner. Through this effort, I have discovered the challenges of making actionable sense of data from a novel virus . . . in real-time. Data sources and definitions are in constant flux, external reporting lacks analytical rigor, and, new knowledge frequently trumps previously held scientific beliefs. More profoundly, models reported on and used extensively by government officials are often accepted as dogma but, may be nothing more than assumptions built upon several more layers of assumptions.

Mark currently serves as the Board Chair of Crown Healthcare Laundry Inc., a Quilvest Private Equity-portfolio company and as Strategic Advisor to Terso Solutions Inc., a subsidiary of Promega that provides Real Time Location Services (RTLS) for field-based inventory of leading medical implant and biotech companies.

He previously served as chief strategist and business intelligence officer for Owens & Minor, Inc.; as a Partner in the healthcare consulting practice at Ernst & Young, where he launched the firm’s health care supply chain practice; and as a Management Engineer at the Detroit Medical Center.

Mark also serves on the National Advisory Board of the Congenital Heart Center at C.S. Mott Children’s Hospital at the University of Michigan, and on the Advisory Board of the Medical Device Supply Chain Council. He recently completed two terms on the Board of the Bellwether League Inc.

In the midst of the COVID-19 situation, Mark is producing an objective and analytical daily report on the virus progression in the US and worldwide. This report has become a go-to source for nearly 2,000 physicians, scientists, health system and supplier executives, economists, investment bankers and, one former head of the Centers for Medicare and Medicaid Services.

Mark holds an MBA from the Ross School of Business at the University of Michigan and a Bachelor of Science in Industrial & Operations Engineering, also from the University of Michigan.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 08 Oct 2020 11:38:55 -0400 2020-10-19T16:30:00-04:00 2020-10-19T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion photo of speaker with event information
CSCS/MIDAS/MICDE Seminar | Predicting the second wave of COVID-19 in Washtenaw County, MI (October 20, 2020 11:30am) https://events.umich.edu/event/76629 76629-19733025@events.umich.edu Event Begins: Tuesday, October 20, 2020 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

This seminar is co-sponsored by the Michigan Institute for Computational Discovery & Engineering (MICDE) and the Michigan Institute for Data Science (MIDAS)

VIRTUAL SEMINAR LINK: myumi.ch/v2ZYv

In this work, we study and predict the spread of COVID-19 in Washtenaw County, MI through applying a discrete and stochastic network-based modeling framework. In this framework, we construct contact networks based on synthetic population datasets specific for Washtenaw County that are derived from US Census datasets. We assign individuals to households, workplaces, schools, and group quarters (such as prisons or long term care facilities). In addition, we assign casual contacts to each individual at random. Using this framework, we explicitly simulate Michigan-specific government-mandated workplace and school closures as well as social distancing measures. We perform sensitivity analyses to identify key model parameters and mechanisms contributing to the observed disease burden in the three months following the first observed cases of COVID-19 in Michigan. We then consider several scenarios for relaxing restrictions and reopening workplaces to predict what actions would be most prudent. In particular, we consider the effects of 1) different timings for reopening, and 2) different levels of workplace vs. casual contact re-engagement. Through simulations and sensitivity analyses, we explore mechanisms driving the magnitude and timing of a second wave of infections upon re-opening.

This work is based on Dr. Renardy's *paper in press* in the *Journal of Theoretical Biology* with coauthors:
Marisa Eisenberg, UM Complex Systems & Math (LSA) and Epidemiology (Public Health)
Denise Kirschner, UM Department of Microbiology & Immunology (Medical School)

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Livestream / Virtual Mon, 28 Sep 2020 14:00:42 -0400 2020-10-20T11:30:00-04:00 2020-10-20T13:00:00-04:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Photo of Marissa Renardy
Human Capital, History, Demography & Development (H2D2): Structural Change, Inequality, and Capital Flows (October 20, 2020 11:30am) https://events.umich.edu/event/78689 78689-20105425@events.umich.edu Event Begins: Tuesday, October 20, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Tue, 20 Oct 2020 11:31:14 -0400 2020-10-20T11:30:00-04:00 2020-10-20T12:50:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
LHS Collaboratory-LHS as a Driver of Diversity, Equity, and Inclusion (October 20, 2020 11:30am) https://events.umich.edu/event/77545 77545-19879862@events.umich.edu Event Begins: Tuesday, October 20, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Healthcare and health remain unconscionably inequitable. This year, the disproportionate toll the COVID-19 pandemic has taken on those historically least well-served by our health system, has highlighted the pressing societal challenge of health disparities.

Beyond simply striving to do no harm, Learning Health Systems (LHSs) have the potential to serve as forces for justice in healthcare and health; indeed, they can be powerful drivers of diversity, equity, and inclusion. LHSs are anchored in multi-stakeholder consensus Core Values that explicitly incorporate principles such as inclusiveness, transparency, and accessibility. Their proximal goal is "to efficiently and equitably serve the learning needs of all participants, as well as the overall public good."

The October 2020 LHS Collaboratory will share lessons from health advocates working on the front lines to make healthcare and health more equitable. These thought leaders and do-ers will illuminate the transformative power of LHSs - and the diverse and inclusive communities of interest that are collaborating to realize them.

Moderator:
Joshua C. Rubin, JD, MBA, MPP, MPH
Program Officer, Learning Health System Initiatives, Department of Learning Health Sciences, University of Michigan

Panelists:
Luis Belén
Chief Executive Officer of the National Health IT Collaborative for the Underserved (NHIT Collaborative)

Danielle Brooks, JD
Director of Health Equity, Amerihealth Caritas

Melissa S. Creary, PhD, MPH, Assistant Professor
Department of Health Management and Policy
School of Public Health, University of Michigan

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Lecture / Discussion Sun, 27 Sep 2020 21:18:37 -0400 2020-10-20T11:30:00-04:00 2020-10-20T13:00:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory Logo puzzle pieces
CCAT Distinguished Lecture Series (October 21, 2020 1:00pm) https://events.umich.edu/event/78174 78174-19989054@events.umich.edu Event Begins: Wednesday, October 21, 2020 1:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

After a long hiatus due to the COVID-19 pandemic, the CCAT Distinguished Lecture Series returns virtually this October with Trevor Pawl!

On July 2nd, Michigan Governor Gretchen Whitmer formally announced the launch of the Office of Future Mobility and Electrification (OFME) with Trevor Pawl named as Chief Mobility Officer. Trevor will provide insight into the creation of OFME, its vision, and its use as a tool for all key mobility stakeholders in Michigan. This webinar will include a Q&A session.
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About the speaker: Trevor Pawl is the Chief Mobility Officer for the State of Michigan, and leads Michigan’s Office of Future Mobility and Electrification. In this position, Pawl is responsible for working across state government, academia and private industry to grow Michigan’s mobility ecosystem through strategic policy recommendations and new support services for companies focused on the future of transportation. Prior to this position, Pawl served as the Senior Vice President of Business Innovation at the MEDC, where he led the official state programs for mobility (PlanetM), supply chain assistance (Pure Michigan Business Connect), export assistance (Michigan International Trade program) and entrepreneurial assistance (Michigan Entrepreneurship and Innovation Program). Before joining the MEDC, Pawl brought with him experience in supply chain matchmaking, having led the creation of the economic development program, Connection Point, at the Detroit Regional Chamber, which later became Pure Michigan Business Connect. Trevor has been named Crain’s Detroit Business’s “40 Under 40” and “50 Names to Know in Government”. He’s also been named Development Counsellors International’s “40 Under 40 Rising Stars of Economic Development” and the Great Lakes Women’s Business Council’s “Government Advocate of the Year”. Pawl holds a Bachelor’s degree in Economics and Marketing from Grand Valley State University and a Master of Business Administration from the University of Detroit Mercy.

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Lecture / Discussion Mon, 05 Oct 2020 16:35:03 -0400 2020-10-21T13:00:00-04:00 2020-10-21T14:00:00-04:00 Off Campus Location Center for Connected and Automated Transportation Lecture / Discussion Decorative Image
Data Science Coast to Coast Presents: Talitha Washington (October 21, 2020 3:00pm) https://events.umich.edu/event/78280 78280-20002864@events.umich.edu Event Begins: Wednesday, October 21, 2020 3:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

The DS C2C seminar series, hosted jointly by six academic data science institutes, provides a unique opportunity to foster a broad-reaching data science community.

Speakers include faculty members and postdoctoral fellows at the six institutes whose research spans the theory and methodology of data science, and their application in arts and humanities, engineering, biomedical, natural, physical and social sciences.

In addition, the series features some of the most important figures in data science, who will provide insight on the transformative use of data science in traditional research disciplines, future breakthroughs in data science research, data science entrepreneurship, and advocacy and national policies for a data-enabled and just society.

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Presentation Wed, 07 Oct 2020 11:23:52 -0400 2020-10-21T15:00:00-04:00 2020-10-21T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation https://umich.zoom.us/j/93769972428
MIPSE Seminar | Bringing Cosmic Shock Waves Down to Earth (October 21, 2020 3:30pm) https://events.umich.edu/event/76462 76462-19717156@events.umich.edu Event Begins: Wednesday, October 21, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

Abstract:
As a fundamental process for converting kinetic to thermal energy, collisionless shocks are ubiquitous throughout the heliosphere and astrophysical systems, from Earth’s magneto-sphere to supernova remnants. While these shocks have been studied for decades by spacecraft, telescopes, and numerical simulations, there remain key open questions in shock physics, such as: How do shocks accelerate particles to extremely high energies? or How are particles heated across a shock? Laboratory experiments thus provide a significant opportunity to both complement spacecraft and remote sensing observations with well-controlled and well-diagnosed datasets, and to help benchmark numerical simulations that bridge laboratory and astrophysical systems.

In this talk, I will discuss recent results from experiments and simulations on the formation and evolution of collision-less shocks created through the interaction of a supersonic laser-driven magnetic piston and magnetized ambient plasma. Through advanced diagnostics a fast, high-Mach-number shock is observed. Direct probing of particle velocity distributions reveals the coupling between the piston and ambient plasmas that is a key step in forming magnetized collisionless shocks. Particle-in-cell simulations further detail the shock formation process, the role of collisionality, and the dynamics of multi-ion-species ambient plasmas. I will also discuss how this experimental platform complements spacecraft missions and can allow novel investigations of shock heating and particle acceleration.

About the Speaker:
Dr. Schaeffer is an Associate Research Scholar in the Department of Astrophysical Sciences at Princeton University. He received his BA in Physics at Cornell University and his PhD in Physics from UCLA, and did his postdoctoral work at Princeton in high-energy-density laboratory astrophysics. Dr. Schaeffer has extensive experience in experiments involving magnetized laser plasmas, collisionless shocks, and magnetic reconnection, and a keen interest in bridging laboratory and astronomical observations. He also has expertise in a wide range of diagnostics, including Thomson scattering, refractive imaging, proton radiography, and x-ray imaging. He has authored dozens of papers and has presented at numerous conferences around the world.

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Livestream / Virtual Tue, 01 Sep 2020 10:51:04 -0400 2020-10-21T15:30:00-04:00 2020-10-21T16:30:00-04:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Livestream / Virtual Dr. Derek Schaeffer
DCMB / CCMB Weekly Seminar (October 21, 2020 4:00pm) https://events.umich.edu/event/78531 78531-20058232@events.umich.edu Event Begins: Wednesday, October 21, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract
Although machine learning applications are now pervasive to every industry, adoption into healthcare remains a challenging and arduous process. Barriers to implementation include clinician trust, algorithm credibility and actionability, promoting clinician literacy in machine learning methods, and mitigating unintended consequences.

In the high-risk operating room setting, anesthesiologists are recognized leaders in patient safety, and manage uncertainty through careful considerations of risk and benefit based upon a thorough understanding of disease processes and treatment mechanisms. In this talk, the speaker highlights how obstacles to implementation of machine-learning based healthcare applications can be mitigated, and how an understanding of such applications can be promoted among clinically-minded anesthesiologists who may not necessarily be expert data scientists.

Short Bio:
Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Associate Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 14 Oct 2020 11:43:15 -0400 2020-10-21T16:00:00-04:00 2020-10-21T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Image which promotes the content of Dr. Mathis' talk (https://jamanetwork.com/collections/5584/critical-care-medicine)
BME Seminar Series: Tyrone Porter (October 22, 2020 4:00pm) https://events.umich.edu/event/75907 75907-19623825@events.umich.edu Event Begins: Thursday, October 22, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:06:51 -0400 2020-10-22T16:00:00-04:00 2020-10-22T17:00:00-04:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Dr. Nahum Melamed on Asteroid Interception (October 22, 2020 7:00pm) https://events.umich.edu/event/78685 78685-20105421@events.umich.edu Event Begins: Thursday, October 22, 2020 7:00pm
Location: Off Campus Location
Organized By: American Institute of Aeronautics and Astronautics

Join the American Institute of Aeronautics and Astronautics this Thursday, October 22nd, for a lecture by Dr. Nahum Melamed on Applying Guidance, Navigation, and Controls Solutions to the Problem of Asteroid Interception for Planetary Defense.

Dr. Melamed is a project leader in the Embedded Control Systems Department in the Guidance and Control Subdivision at The Aerospace Corporation who validates and certifies the flight software and mission parameters for the Delta IV launch vehicles, and conducts planetary defense technical and policy studies. He earned a PhD in Aerospace Engineering from Georgia Tech.

If you're interested please add your name to the spreadsheet linked below.

When: Thursday, 22 October 2020 at 7pm ET (4pm PT)
Where: Zoom (see link below, passcode 424378)

We hope to see you there!!

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Lecture / Discussion Tue, 20 Oct 2020 10:08:36 -0400 2020-10-22T19:00:00-04:00 2020-10-22T20:15:00-04:00 Off Campus Location American Institute of Aeronautics and Astronautics Lecture / Discussion lecture flyer
Biophysics Seminar Series (October 23, 2020 12:00pm) https://events.umich.edu/event/77918 77918-19941583@events.umich.edu Event Begins: Friday, October 23, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

*Please see below for the link to join the Zoom event.*

The Biophysics Virtual Seminar Series presents:

Dr. Sandra Schmid - Chief Scientific Officer, Chan Zuckerberg Biohub

“Dynamin: A catalyst for fission, collaboration and controversy”

ABSTRACT: Kazuo Ikeda’s beautiful electron micrographs of neuromuscular junctions of Drosophila *shibire* mutants revealed the presence of collar-like structures around the necks of trapped endocytic intermediates. They inspired my 30 year-long obsession with dynamin, the mammalian homologue of *shibire.* Our subsequent studies of dynamin, which began in the early 90s provide benefitted from the development of new technologies and from interdisciplinary collaboration. I’ll describe the twists and turns of our efforts to understand the mechanisms underlying dynamin-catalyzed fission, the value of interdisciplinary collaborations, and the importance of taking all data into account when formulating models. I’ll detail our current understanding of dynamin-catalyzed fission, now supported by independent studies of others, and briefly describe the many remaining unanswered questions, keeping in mind (in the words of George Box) that, *“All models are wrong, but some are useful."*

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Livestream / Virtual Mon, 19 Oct 2020 15:12:59 -0400 2020-10-23T12:00:00-04:00 2020-10-23T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Sandra Schmid
Special Joint Seminar - Hosted by DCMB, Department of Mathematics, and the Smale Institute (October 26, 2020 12:00pm) https://events.umich.edu/event/78673 78673-20099541@events.umich.edu Event Begins: Monday, October 26, 2020 12:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Dr. Leland Hartwell won the Nobel Prize in Physiology or Medicine in 2001 for the discoveries of key regulators of the cell cycle.

“We want our students to have an authentic experience of science. Nearly all science activities designed for schools require the students to demonstrate an established scientific principle by getting the right answer. Getting the “right” answer is not authentic science. Science is the exploration of the unknown – the answer cannot be known.“
- Leland Hartwell

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Livestream / Virtual Mon, 19 Oct 2020 13:04:27 -0400 2020-10-26T12:00:00-04:00 2020-10-26T13:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Dr. Leland Hartwell, Nobel Laureate
Fair Ranking with Biased Data (October 26, 2020 4:00pm) https://events.umich.edu/event/78276 78276-20002859@events.umich.edu Event Begins: Monday, October 26, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Search engines and recommender systems have become the dominant matchmaker for a wide range of human endeavors — from online retail to finding romantic partners. Consequently, they carry immense power in shaping markets and allocating opportunity to the participants. In this talk, I will discuss how the machine learning algorithms underlying these systems can produce unfair ranking policies for both exogenous and endogenous reasons. Exogenous reasons often manifest themselves as biases in the training data, which then get reflected in the learned ranking policy and lead to rich-get-richer dynamics. But even when trained with unbiased data, reasons endogenous to the algorithms can lead to unfair or undesirable allocation of opportunity. To overcome these challenges, I will present new machine learning algorithms that directly address both endogenous and exogenous unfairness.

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Presentation Wed, 07 Oct 2020 10:09:21 -0400 2020-10-26T16:00:00-04:00 2020-10-26T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation https://umich.zoom.us/j/93790126046
Analyzing the Value of Flexibility in Design & Operations of Outpatient Health Centers (October 26, 2020 4:30pm) https://events.umich.edu/event/78742 78742-20115266@events.umich.edu Event Begins: Monday, October 26, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Although it is understood that healthcare systems are complex and dynamic systems, many times the operations of these systems, particularly around the allocation of fixed resources and physical space, is treated as fixed or static. As such policies regarding (i) the flow of patients, (ii) allocation of exam rooms, or (iii) the assignment of medical assistants to physicians are set at the beginning of the day, week or month, and remain unchanged across that duration. While the static nature of these schemes are meant to support stability and reduced complexity in the operations, this fixed mindset can hinder the ability to drive quality improvement. This presentation will review applications of simulation modeling in support of assessing the value that can be obtained from integrating flexibility into operational policies. We will review dynamic room allocation policies and staffing policies as applied to a crowded cardiovascular clinic. Additionally, we will explore similar concepts in multiple orthopedic clinics. Finally, we will present how these concepts can be similarly examined with a continuous-time Markov model.

Jackie Griffin is an Associate Professor in the Mechanical and Industrial Engineering Department at Northeastern University. Her research focuses on applications of Operations Research, Optimization, and Simulation methodologies in designing, managing and operating resilient healthcare delivery systems, ranging from outpatient clinics to regional emergency response networks to global pharmaceutical supply chains. Currently she leads a National Science Foundation funded project focused on tackling the ongoing challenge of drug shortages in the United States through the analysis of analytical models of pharmaceutical supply chains. Additionally, she has partnered with many prominent healthcare organizations to examine new strategies for improving the design and operation of health care systems while accounting for the need to balance multiple system objectives in ensuring delivery of high quality health care services. Her recent collaborations include organizations such as Massachusetts General Hospital, Tufts Medical Center, Boston Children’s Hospital, Beth Israel Hospital, Brigham and Women’s Hospital, and the IQVIA Institute for Human Data Science. Other past collaborators include the Centers for Disease Control and Prevention (CDC), Children’s Healthcare of Atlanta, DeKalb Medical Women’s Center, Emory University Hospital, Grady Memorial Hospital, and World Vision International. She received her PhD from the H. Milton Stewart School of Industrial and Systems Engineering at Georgia Institute of Technology. Additionally, she completed her MS and BS degrees in the Industrial and Systems Engineering department at Lehigh University.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 21 Oct 2020 17:19:55 -0400 2020-10-26T16:30:00-04:00 2020-10-26T17:30:00-04:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Jackie Griffin, Ph.D.
Human Capital, History, Demography & Development (H2D2): Black Economic Progress in the Jim Crow South: Evidence from Rosenwald Schools (October 27, 2020 11:30am) https://events.umich.edu/event/78911 78911-20152765@events.umich.edu Event Begins: Tuesday, October 27, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Mon, 26 Oct 2020 11:56:07 -0400 2020-10-27T11:30:00-04:00 2020-10-27T12:50:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
DCMB / CCMB Seminar (October 28, 2020 4:00pm) https://events.umich.edu/event/78528 78528-20058229@events.umich.edu Event Begins: Wednesday, October 28, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Single-cell RNA sequencing (scRNA-seq) allows researchers to examine the transcriptome at the single-cell resolution and has been increasingly employed as technologies continue to advance. Due to technical and biological reasons unique to scRNA-seq data, clustering and batch effect correction are almost indispensable to ensure valid and powerful data analysis. Multiple methods have been proposed for these two important tasks. For clustering, we have found that different methods, including state-of-the-art methods such as Seurat, SC3, CIDR, SIMLR, t-SNE + k-means, yield varying results in terms of both the number of clusters and actual cluster assignments. We have developed ensemble methods, SAFE-clustering and SAME-clustering, that leverages hyper-graph partitioning algorithms and a mixture model-based approach respectively to produce more robust and accurate ensemble solution on top of clustering results from individual methods. For batch effect correction, we have developed methods based on supervised mutual nearest neighbor detection to harness the power of known cell type labels for certain single cells. We benchmarked all methods in various scRNA-seq datasets to demonstrate their utilities.

Short bio: Yun Li, PhD is an Associate professor of Genetics and Biostatistics at the University of North Carolina, Chapel Hill. Dr. Li is a statistical geneticist with extensive experiences with method development and application on genotype imputation (developer of MaCH and MaCH-admix), genetic studies of recently admixed population, design and analysis of sequencing-based studies, analyses of multi-omics data including mRNA expression, DNA methylation and chromatin three dimensional organization. Dr. Li has been playing an active role in genetic studies of complex human traits resulting many GWAS and meta-analysis publications, including >30 in Nature, Science, Cell, and Nature Genetics. Dr. Li has been leading multiple R01 projects on statistical method development for complex trait genetics. Dr. Li has also been the Director for the Data Science Core of IDDRC (Intellectual and Developmental Disabilities Research Center). Dr. Li has received many awards and became the Thomson Reuters Highly Cited Researcher due to her high impact scientific work. Specifically, her work has been cited >60,000 times with h-index of 64 and i10-index of 113.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 14 Oct 2020 10:41:20 -0400 2020-10-28T16:00:00-04:00 2020-10-28T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Yun Li, PhD (Associate Professor of Genetics & Biostatistics; Adjunct Associate Professor, Applied Physical Sciences at School of Medicine, Genetics at University of North Carolina)
BME Seminar Series: Sudin Bhattacharya (October 29, 2020 4:00pm) https://events.umich.edu/event/75908 75908-19623826@events.umich.edu Event Begins: Thursday, October 29, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:09:37 -0400 2020-10-29T16:00:00-04:00 2020-10-29T17:00:00-04:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Biophysics Seminar Series (October 30, 2020 12:00pm) https://events.umich.edu/event/77919 77919-19941584@events.umich.edu Event Begins: Friday, October 30, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

Join us on Zoom: https://umich.zoom.us/j/91037518250

The Biophysics Virtual Seminar Series presents:

Dr. Ido Golding - Professor of Physics, School of Molecular & Cellular Biology, University of Illinois Urbana-Champaign

"Illuminating bacterial individuality"

ABSTRACT: Single-cell measurements of mRNA copy numbers inform our understanding of stochastic gene expression, but these measurements coarse-grain over the individual copies of the gene, where transcription and its regulation take place stochastically. We recently combined single-molecule quantification of mRNA and gene loci to measure the transcriptional activity of an endogenous gene in
individual Escherichia coli bacteria. When interpreted using a theoretical model for mRNA dynamics, the single-cell data allowed us to obtain the probabilistic rates of promoter switching, transcription initiation and elongation, mRNA release and degradation. Unexpectedly, we found that gene activity can be strongly coupled to the transcriptional state of another copy of the same gene present in the cell, and to the event of gene replication during the bacterial cell cycle. These gene-copy and cell-cycle correlations demonstrate the limits of mapping whole-cell mRNA numbers to the underlying stochastic gene activity and highlight the contribution of previously hidden variables to the observed population heterogeneity.

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Livestream / Virtual Mon, 26 Oct 2020 09:26:15 -0400 2020-10-30T12:00:00-04:00 2020-10-30T13:00:00-04:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Ido Golding
Economics at Work (October 30, 2020 1:00pm) https://events.umich.edu/event/78078 78078-19957577@events.umich.edu Event Begins: Friday, October 30, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/nCQSPmbG9in5xSoN8

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Workshop / Seminar Thu, 01 Oct 2020 17:22:28 -0400 2020-10-30T13:00:00-04:00 2020-10-30T14:30:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Rightsizing Prenatal Care: Tailoring Prenatal Services to Match Patients’ Needs (November 2, 2020 5:30pm) https://events.umich.edu/event/78743 78743-20115267@events.umich.edu Event Begins: Monday, November 2, 2020 5:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Please note the seminar starts at 5:30 PM EST, an hour later than our usual seminar time.

Each year, nearly 4 million women who give birth in the United States receive prenatal care—a crucial preventive service that improves pregnancy outcomes for mothers and their children. National guidelines currently recommend 12 to 14 in-person prenatal visits for all patients regardless of medical or social needs. This schedule recommends more care for low-risk women than peer countries with better outcomes that the U.S., and has remained unchanged since 1930, failing to adapt to the needs of modern patients. Current prenatal care has also failed to address significant inequities in maternity care: low-income and black patients less likely to receive recommended services before delivery, and are more likely to suffer from severe maternal morbidity and mortality in pregnancy.

Although we know that prenatal care services (e.g. laboratory tests and vaccinations) are evidence based, these evidence-based services can be delivered in fewer than 14 visits. There is also evidence that patients do not need to visit clinics in person to receive all maternity services. This schedule results in overutilization of care for low-risk pregnant patients, and potential access issues for patients with more intense needs in pregnancy. In this talk, we will review the evidence supporting prenatal care and new delivery models. We will then introduce a new conceptual model for redesigning prenatal care to meet patients’ diverse medical and social needs, and demonstrate how this model can be used to test new models of prenatal care to drive appropriate resource allocation. We will conclude with early findings from new models that were launched during the COVID-19 pandemic with a focus on ensuring new prenatal care delivery is effective, efficient and equitable.

Dr. Alex Peahl is an Obstetrician Gynecologist and physician-investigator in the Department of Obstetrics and Gynecology at the University of Michigan. Her research focuses on how to improve the effectiveness, efficiency and equity of reproductive health care through developing, studying and disseminating high-quality maternity care interventions. She is a nationally recognized expert on prenatal care redesign and innovation and has completed seminal studies and thought pieces on how to best incorporate patients’ preferences and needs into rightsized prenatal care plans: plans that match patients’ needs to services delivered. She is the research lead for prenatal care redesign at the University of Michigan, and new guidelines driven by her team were recognized by the American College of Obstetricians and Gynecologists as the example for nationwide practice during the COVID-19 pandemic. She is currently leading the Michigan Plan for Appropriate, Tailored Healthcare in Pregnancy, a national consensus process to develop new prenatal care guidelines in pregnancy.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 21 Oct 2020 17:28:03 -0400 2020-11-02T17:30:00-05:00 2020-11-02T18:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Alex Peahl, MD, MSc
Human Capital, History, Demography & Development (H2D2): Demand Shocks, Staffing Decisions, and Firm Performance: Evidence from the Introduction of a Food Delivery Platform in Colombia (November 3, 2020 11:30am) https://events.umich.edu/event/78920 78920-20154730@events.umich.edu Event Begins: Tuesday, November 3, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Mon, 26 Oct 2020 13:59:09 -0400 2020-11-03T11:30:00-05:00 2020-11-03T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIPSE Seminar | Quantum Hydrodynamics and Rayleigh-Taylor Instability (November 4, 2020 3:30pm) https://events.umich.edu/event/76466 76466-19717159@events.umich.edu Event Begins: Wednesday, November 4, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

Abstract:
Matter at extreme pressures, temperatures, and densities characterizes a wide variety of natural and man-made phenomena, including interiors of Jovian size planets, hyper-velocity meteor impacts, the burning core of stars, thermonuclear burning inertial confinement fusion capsules. Matter at these conditions defines the exciting and challenging field of High Energy Density Physics (HEDP). Besides vast experimental resources, there exists a rich set of computational tools that model the micro to macro regimes of HEDP. Recently, there has been a resurgence in interest in using a “simpler” approach to investigating HEDP based on quantum hydrodynamics. Quantum Hydrodynamics (QHD) has a long and interesting history, dating back to the first developments by Madelung and Bohm. In this talk, we discuss the historical and recent developments in QHD, including pitfalls, as applied to quantum many-body systems relevant to HEDP regimes. We will present three different approaches to deriving the QHD equations-Madelung, Bloch, and Wigner and discuss their pros and cons. Finally, the role that Rayleigh-Taylor hydrodynamic instabilities play is discussed within the QHD formalism.

About the Speaker:
Frank Graziani received a BS in physics from Santa Clara U., and a PhD in physics from UCLA. He was a postdoctoral fellow at U. Colorado and U. Minnesota working in cosmology and particle physics; and worked with NASA on exoplanet dynamics and star formation. Dr. Graziani joined Lawrence Livermore National Lab. in 1989 where he worked in radiation transport and plasma physics. He has held many leadership positions at LLNL, including group leader, V&V Leader, PI for LDRD-Strategic Initiatives, lead for the National Boost Initiative and Assoc. Division Leader for computational physics. He now directs the High Energy Density Sciences Center. He has won four DOE Defense Program Awards of Excellence, the LLNL Director’s S&T Award and is a Distinguished Member of the Technical Staff. His research interests include the micro-physics of dense plasmas and HED education. Dr. Graziani is editor of two books on computational methods and a book on warm dense matter physics.

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Livestream / Virtual Tue, 01 Sep 2020 10:59:54 -0400 2020-11-04T15:30:00-05:00 2020-11-04T16:30:00-05:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Livestream / Virtual Dr. Frank Graziani
DCMB / CCMB Weekly Seminar (November 4, 2020 4:00pm) https://events.umich.edu/event/78770 78770-20121164@events.umich.edu Event Begins: Wednesday, November 4, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Metabolomics is a powerful approach to characterize small molecules produced in cells, tissues, and other biological systems. Metabolites are direct products of enzymatic reactions and provide a snapshot of cellular activities. Metabolomics-based research has already had a profound impact on biomarker discovery, nutritional analysis, and other biomedical and biological discoveries. The most pressing problem in metabolomics however is identifying compounds in the sample-under-study from the metabolomics measurements. Current analysis tools are capable of annotating only a small portion of sample measurements.

In this talk, we present machine learning solutions to three challenges related to the interpretation of metabolomics data. To mimic the function of a mass spectrometer in generating a mass spectrum, we use graph neural networks to translate a molecular structure into its respective spectral signature. To interpret the biological measurements in the context of the biological sample, we use Bayesan learning to deduce the likelihood of pathway activities. To suggest putative candidate molecules that are biologically relevant matches to the measured spectra, we explore several methods for predicting possible enzymatic products. We discuss several results, highlighting the value of using machine learning for advancing metabolomics analysis.

Short bio: Soha Hassoun is Professor and Past Chair of the Department of Computer Science at Tufts University. Soha received her undergraduate degree in Electrical Engineering from South Dakota State University, the Master's degree from MIT, and the Ph.D. degree from the Department of Computer Science and Engineering, University of Washington in Seattle. Soha’s lab uses Machine Learning to develop analysis and discovery tools for synthetic and systems biology, with a focus on enzyme promiscuity prediction and metabolomics analysis. Soha was a recipient of the NSF CAREER Award, and several technical and service awards from various professional societies. She provided technical leadership for several conferences including ICCAD and DAC. She co-founded the International Workshop on Bio-Design Automation in 2009. Soha serves on the board of the Computing Research Association's Committee on Widening Participation in Computing Research.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 22 Oct 2020 11:33:23 -0400 2020-11-04T16:00:00-05:00 2020-11-04T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics (November 4, 2020 4:00pm) https://events.umich.edu/event/79058 79058-20184340@events.umich.edu Event Begins: Wednesday, November 4, 2020 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Details to Come.

* To join the seminar, please contact at econ.events@umich.edu

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Other Fri, 30 Oct 2020 09:22:57 -0400 2020-11-04T16:00:00-05:00 2020-11-04T17:00:00-05:00 Off Campus Location Department of Economics Other Econ Umich
BME Seminar Series: Lori Setton (November 5, 2020 4:00pm) https://events.umich.edu/event/75909 75909-19623827@events.umich.edu Event Begins: Thursday, November 5, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:14:30 -0400 2020-11-05T16:00:00-05:00 2020-11-05T17:00:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Biophysics Seminar Series (November 6, 2020 12:00pm) https://events.umich.edu/event/77920 77920-19941585@events.umich.edu Event Begins: Friday, November 6, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Nozomi Ando - Assistant Professor of Chemistry & Chemical Biology, Cornell University

*"Protein Allostery: Evolution and Correlated Motions"*

Join us on Zoom: https://umich.zoom.us/j/99976448506

ABSTRACT: Understanding the relationship between protein sequence, structure, dynamics, and function is the ultimate goal of structural biology. For this reason, my lab studies protein allostery - a special property of macromolecules that connects molecular motion and action. In this talk, I'll present two stories. First, I'll talk about how the evolution of allosteric mechanisms and the tools of structural biology can teach us about the relationship between protein sequence and function. In the second story, I'll talk about how one can learn about correlated motions that give rise to allostery.

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Livestream / Virtual Mon, 02 Nov 2020 09:56:44 -0500 2020-11-06T12:00:00-05:00 2020-11-06T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Nozomi Ando
MCDB Virtual: Olfactory Navigation in Drosophila--Algorithms and Circuits (November 6, 2020 12:00pm) https://events.umich.edu/event/77405 77405-19848067@events.umich.edu Event Begins: Friday, November 6, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Josie Clowney

Abstract: Olfactory navigation provides a tractable model for studying the circuit basis of sensori-motor transformations and goal-directed behavior. Macroscopic organisms typically navigate in odor plumes that provide a noisy and uncertain signal about the location of an odor source. Work in many species has suggested that animals accomplish this task by combining temporal processing of dynamic odor information with an estimate of wind direction.

Our lab has been using adult walking Drosophila to understand both the computational algorithms and the neural circuits that support navigation in a plume of attractive food odor. We developed a high-throughput paradigm to study behavioral responses to temporally-controlled odor and wind stimuli. Using this paradigm we found that flies respond to a food odor (apple cider vinegar) with two behaviors: during the odor they run upwind, while after odor loss they perform a local search. A simple computational model based one these two responses is sufficient to replicate many aspects of fly behavior in a natural turbulent plume.

In on-going work, we are seeking to identify the neural circuits and biophysical mechanisms that perform the computations delineated by our model. Using electrophysiology, we have identified mechanosensory neurons that compute wind direction from movements of the two antennae, and central mechanosensory neurons that encode wind direction are involved in generating a stable downwind orientation. Using optogenetic activation, we have traced olfactory circuits capable of evoking upwind orientation and offset search from the periphery, through the mushroom body and lateral horn, to the central complex. Most recently, connectomic analysis has suggested a plausible model for how wind and odor information might be integrated in the central complex to allow flies to flexibly alter their orientation to wind. Our work illustrates how the tools available in fruit fly can be applied to dissect the mechanisms underlying a complex goal-directed behavior.

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Workshop / Seminar Mon, 26 Oct 2020 15:53:06 -0400 2020-11-06T12:00:00-05:00 2020-11-06T13:00:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Katherine Nagel with lab view behind her
Economics at Work (November 6, 2020 1:00pm) https://events.umich.edu/event/78079 78079-19957578@events.umich.edu Event Begins: Friday, November 6, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/QYre9DYYtmq8Wpe89

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Workshop / Seminar Thu, 01 Oct 2020 17:25:52 -0400 2020-11-06T13:00:00-05:00 2020-11-06T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economic Theory: Persuading Statisticians (November 6, 2020 2:30pm) https://events.umich.edu/event/81680 81680-20941464@events.umich.edu Event Begins: Friday, November 6, 2020 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
A decision maker (DM) contemplates whether to take a costly action. The DM does not know the action's value and relies on data and unbiased statistical inference to estimate it. The data are Bernoulli experiments governed by the action's value. A designer, who wishes the DM to take the action, controls the size of the data, i.e., the sample size, available to the DM. We establish that in many environments the designer's optimal sample size is the largest one satisfying that either a single --- or a simple majority --- of favorable realizations would persuade the DM to take the action.

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Workshop / Seminar Wed, 03 Feb 2021 11:53:54 -0500 2020-11-06T14:30:00-05:00 2020-11-06T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Social, Behavioral & Experimental Economics (SBEE): Disguising Prejudice: Popular Rationales as Excuses for Intolerant Expression (November 10, 2020 10:00am) https://events.umich.edu/event/79006 79006-20170600@events.umich.edu Event Begins: Tuesday, November 10, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We study the use of popular rationales to justify public anti-minority actions. Rationales to oppose minorities change some people's private opinions, leading them to take anti-minority actions even if they are not prejudiced against minorities. When these rationales become widespread, prejudiced people can pool with unprejudiced people who are persuaded, decreasing the stigma associated with anti-minority expression and enabling greater public opposition to minority groups. In a first experiment, subjects learn that a previous respondent authorized a donation to an anti-immigrant organization and then make an inference about the respondent's underlying motivations. Subjects informed that their matched respondent learned about a study claiming that immigrants increase crime rates before authorizing the donation see the respondent as less intolerant and more easily persuadable. In a second experiment, subjects learn about that same study and then choose whether to authorize a publicly observable donation to the anti-immigrant organization. Subjects who are informed that their exposure to the rationale will be publicly observable are substantially more likely to make the donation than subjects who believe that their exposure will remain anonymous. Our findings suggest that prominent public figures can lower the social cost of intolerant expression by popularizing rationales, contributing to waves of anti-minority behavior.

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Workshop / Seminar Wed, 28 Oct 2020 15:23:25 -0400 2020-11-10T10:00:00-05:00 2020-11-10T11:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Students’ mobility patterns on campus and the implications for the recovery of campus activities post-pandemic (November 10, 2020 10:30am) https://events.umich.edu/event/79204 79204-20231445@events.umich.edu Event Begins: Tuesday, November 10, 2020 10:30am
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

This research project uses location data gathered from WiFi access points on campus to model the mobility patterns of students in order to inform the planning of educational activities that can minimize the transmission risk.
The first aim is to understand the general mobility patterns of students on campus to identify physical spaces associating with a high-risk of transmission. For example, we can extract insights from WiFi data about which locations are the busiest during which time of the day, how much time was typically spent at each location, and how do these mobility patterns change over time. The second aim is to understand how students share the same physical spaces on campus (e.g. attending a lecture, meeting in the same room, sharing the same dorm). Students are presumably in a close proximity when they are connected to the same WiFi access point. We model a student-to-student network from their co-location activities and use its network centrality measures as proxies of transmission risk (i.e. students in the center of a network would have a higher chance of getting exposed to COVID-19 than those in the periphery). We then correlate network centrality measures with academic information (e.g. class schedule, course enrollment, study major, year of study, gender, ethnicity) to determine whether certain features of the academic record are related to transmission risk. For example, we can identify which groups of students are more vulnerable to potential infections by associating with a high network centrality. Insights from this research project will inform the University of Michigan’s strategies for the recovery of educational activities post-pandemic with empirical evidence of students’ mobility pattern on campus as well as factors that associate with a high-risk of transmission.

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Presentation Thu, 05 Nov 2020 09:35:37 -0500 2020-11-10T10:30:00-05:00 2020-11-10T10:50:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Quan Nguyen
Human Capital, History, Demography & Development (H2D2): Legacies of Colonial Rule and the HIV Epidemic in Africa: Evidence from the Mozambique Company Concession (November 10, 2020 11:30am) https://events.umich.edu/event/78921 78921-20154731@events.umich.edu Event Begins: Tuesday, November 10, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Mon, 26 Oct 2020 14:02:42 -0400 2020-11-10T11:30:00-05:00 2020-11-10T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Of Moms and Microbes: Pregnancy and the Microbiome (November 10, 2020 12:00pm) https://events.umich.edu/event/79039 79039-20178452@events.umich.edu Event Begins: Tuesday, November 10, 2020 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Kimberly McKee, PhD, Assistant Professor of Family Medicine at the UM Medical School will present a seminar, with Q&A, on "Of Moms and Microbes: Pregnancy and the Microbiome".

ZOOM link:
https://umich.zoom.us/j/97328685723

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Lecture / Discussion Thu, 29 Oct 2020 13:13:13 -0400 2020-11-10T12:00:00-05:00 2020-11-10T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Environmental Research Seminar
DCMB / CCMB Weekly Seminar (November 11, 2020 4:00pm) https://events.umich.edu/event/79286 79286-20264787@events.umich.edu Event Begins: Wednesday, November 11, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: There is a growing understanding that stress and depression during the process of training to become physicians is high. In this talk, we will discuss how we have used mobile and wearable data as well as genomics to understand the prevalence in the US and China, drivers and possible solutions about training physician depression and how the COVID-19 pandemic has affected them in the two countries.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 09 Nov 2020 14:13:58 -0500 2020-11-11T16:00:00-05:00 2020-11-11T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Drs. Margit Burmeister and Srijan Sen
Michael Beauregard Seminar in Macroeconomics: Scalable Expertise (November 11, 2020 4:00pm) https://events.umich.edu/event/79059 79059-20184343@events.umich.edu Event Begins: Wednesday, November 11, 2020 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We document that aggregate or sectoral demand shocks have disproportionately bigger effects on larger firms. Changes in scope, the number of products/locations, plays a significant role in this heterogeneity. Motivated by these facts, we present a theory of firm size, where both scope and expertise (which determines revenues and profits) are chosen endogenously. The extent to which expertise is scalable (applicable to multiple products), as opposed to local (specific to a particular product), is also chosen by the firm. The model predicts rich heterogeneity in responses to a sector-wide demand shock: firms with higher revenue per product (conditional on scope) adjust their scope by less, while those with higher scope (conditional on revenue per peroduct) adjust by more. Using data on multi-product and multi-establishment firms, we provide empirical evidence in support of these predictions. We also construct a proxy for the scalability of the firm’s expertise and show that the predictions of the model with respect to the scalability of firm-level expertise, both in the cross-section and in response to shocks, are also consistent with the patterns observed in the data.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 09 Nov 2020 17:22:03 -0500 2020-11-11T16:00:00-05:00 2020-11-11T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
A New Perspective on Amelogenesis and Dental Diagnoses (November 12, 2020 12:00pm) https://events.umich.edu/event/79191 79191-20225570@events.umich.edu Event Begins: Thursday, November 12, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

James P. Simmer, DDS, PhD Professor of Dentistry
Biologic and Materials Sciences & Prosthodontics
University of Michigan School of Dentistry

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Lecture / Discussion Wed, 04 Nov 2020 15:24:08 -0500 2020-11-12T12:00:00-05:00 2020-11-12T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Simmer
BME Seminar Series: Eytan Ruppin (November 12, 2020 4:00pm) https://events.umich.edu/event/75910 75910-19623828@events.umich.edu Event Begins: Thursday, November 12, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:22:54 -0400 2020-11-12T16:00:00-05:00 2020-11-12T17:00:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Michael Woodroofe Lecture Series: Emery Brown, Director of the Harvard–MIT Program of Health Sciences and Technology (November 13, 2020 10:00am) https://events.umich.edu/event/76734 76734-19741053@events.umich.edu Event Begins: Friday, November 13, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: General anesthesia is a drug-induced, reversible condition comprised of five behavioral states: unconsciousness, amnesia (loss of memory), antinociception (loss of pain sensation), akinesia (immobility), and hemodynamic stability with control of the stress response. Our work shows that a primary mechanism through which anesthetics create these altered states of arousal is by initiating and maintaining highly structured oscillations. These oscillations impair communication among brain regions. We illustrate this effect by presenting findings from our human studies of general anesthesia using high-density EEG recordings and intracranial recordings. These studies have allowed us to give a detailed characterization of the neurophysiology of loss and recovery of consciousness due to propofol. We show how these dynamics change systematically with different anesthetic classes and with age. We have developed a principled, neuroscience-based paradigm for using the EEG to monitor the brain states of patients receiving general anesthesia. We demonstrate that the state of general anesthesia can be rapidly reversed by activating specific brain circuits. Finally, we demonstrate that the state of general anesthesia can be controlled using closed loop feedback control systems. The success of our research has depended critically on tight coupling of experiments, signal processing research and mathematical modeling.

Biography: Emery N. Brown, M.D., Ph.D. is the Warren M. Zapol Professor of Anaesthesia at Harvard Medical School; an anesthesiologist at Massachusetts General Hospital; and the Edward Hood Taplin Professor of Medical Engineering and Computational Neuroscience at MIT. Brown is an anesthesiologist-statistician whose research is defining the neuroscience of how anesthetics produce general anesthesia. He also develops statistical methods for neuroscience data analysis. Dr. Brown has received the American Society of Anesthesiologists Excellence in Research Award and the Dickson Prize in Science and the Swartz Prize for Computational and Theoretical Neuroscience. He is a fellow of the American Academy of Arts Sciences and the National Academy of Inventors. Dr. Brown is a member of the National Academy of Medicine, National Academy of Sciences and the National Academy of Engineering.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow.

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Workshop / Seminar Tue, 10 Nov 2020 14:47:46 -0500 2020-11-13T10:00:00-05:00 2020-11-13T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Emery Brown
Biophysics Seminar Series (November 13, 2020 12:00pm) https://events.umich.edu/event/77921 77921-19941586@events.umich.edu Event Begins: Friday, November 13, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Nancy Forde - Department of Physics, Simon Fraser University

*“Collagen: a fascinating responsive material building block from Nature”*

Join us on Zoom: https://umich.zoom.us/j/96009492561

Abstract: Multicellular life is scaffolded by structures that maintain cells in the desired locations and organizations. Conventionally these extracellular scaffolds have been viewed as rigid, unchanging supports laid down during development and unaltered except by injury or disease. Recent scientific advances are revealing instead that these matrices are highly dynamic and respond to changes in their local microenvironment, in turn affecting cells. The collagen family of proteins has been selected via evolution as the preferred building block of these extracellular structures.

In this talk, I will introduce some of the fascinating physical properties of the unique triple-helix structure of collagen, and will highlight the results of our investigations into its mechanical properties. Our single-molecule approaches include centrifuge force microscopy, optical tweezers and atomic force microscopy, and many parallels can be drawn with the mechanics of DNA. Our work is revealing clues as to how stability is encoded within collagen’s sequence, and how collagen’s triple helix balances structural stability with responsiveness to applied force and chemical environment.

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Livestream / Virtual Wed, 04 Nov 2020 11:44:26 -0500 2020-11-13T12:00:00-05:00 2020-11-13T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Nancy Forde
Economics at Work (November 13, 2020 1:00pm) https://events.umich.edu/event/78080 78080-19957579@events.umich.edu Event Begins: Friday, November 13, 2020 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/eLwgQ3wda3DmtZ6eA

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Workshop / Seminar Thu, 01 Oct 2020 17:28:58 -0400 2020-11-13T13:00:00-05:00 2020-11-13T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Honors Seminar Series: Ethan Kross (November 13, 2020 2:00pm) https://events.umich.edu/event/76513 76513-19719174@events.umich.edu Event Begins: Friday, November 13, 2020 2:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

On October 8, 2013 Malala Yousafzai appeared on the Daily Show to talk about her harrowing experience surviving the Taliban’s attempt to assassinate her. At one point during the interview she described how she reacted when she discovered that the Taliban were planning to kill her. “I used to think that the Tali[ban] would come and he would just kill me,” she told to Stewart. “But then I said, if he comes, what would you do Malala? Then I would reply to myself, Malala just take a shoe and hit him…”

Malala’s interview provides a window into the at times curious ways that we reflect on our lives. Although we all have an inner monologue that we engage in from time to time, an inner voice that guides our moment-to-moment reflections, people often report referring to themselves in strikingly different ways when they introspect. Whereas people typically use 1st person singular pronouns (e.g., I, me, my) to refer to themselves during introspection, they at times also use their own name and other non-1st-person pronouns to refer to themselves as well.

In this talk, Professor Ethan Kross will review findings from a growing body of psychological and neuroscience research, which suggests that far from representing a simple quirk of speech, engaging in such distanced self-talk enhances people’s ability to control their thoughts, feelings and behavior under stress.

You can register here: https://myumi.ch/0W1Op

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Workshop / Seminar Thu, 29 Oct 2020 09:47:52 -0400 2020-11-13T14:00:00-05:00 2020-11-13T15:00:00-05:00 Off Campus Location LSA Honors Program Workshop / Seminar Professor Ethan Kross
Economic Theory: Caution and Reference Effects (oint with Simone Cerreia-Vioglio and David Dillenberger) (November 13, 2020 2:30pm) https://events.umich.edu/event/81681 81681-20941465@events.umich.edu Event Begins: Friday, November 13, 2020 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We establish a theoretical link between three phenomena at the core of behavioral economics: the Endowment Effect, Loss Aversion, and violations of Expected Utility as in the Certainty Effect. In our model, all jointly stem from one single force: uncertainty about the utility function to use and caution. Behaviorally, we show that our model is derived from positing a form of the certainty effect, that we show implies both Loss Aversion and the Endowment Effect. We analyze further implications of our model and demonstrate how it can organize existing empirical evidence of the Endowment Effect, and how it is conceptually and behaviorally distinct from other popular approaches, e.g., Cumulative Prospect Theory.

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Workshop / Seminar Wed, 03 Feb 2021 11:56:40 -0500 2020-11-13T14:30:00-05:00 2020-11-13T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Optimal Influenza Vaccine Distribution With Equity (November 16, 2020 4:30pm) https://events.umich.edu/event/79331 79331-20272794@events.umich.edu Event Begins: Monday, November 16, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Influenza is a serious public health concern. Each year 5-15% of the world’s population is infected with influenza resulting in 3-5 million severe cases and 250,000-500,000 deaths. This presentation is concerned with the optimal influenza vaccine distribution in a heterogeneous population consisting of multiple subgroups. In our experiments, each subgroup corresponds to a set of people within an age group living in a certain geographic area, however the definition of subgroup is flexible. For example, healthcare workers or nursing home residents can be considered as subgroups in real life policy decisions. To characterize the spread of influenza through interacting subgroups, we employ an epidemic model that incorporates transmission dynamics and social distancing. The epidemic model is then coupled with a nonlinear mathematical program to find the critical vaccine allocation that minimizes vaccine usage. We also include an equity constraint to help public health authorities find a balanced vaccine allocation policy with respect to equity and effectiveness. Several detailed epidemic simulation models are developed in the literature to evaluate vaccination policies before their implementation so as to efficiently allocate resources. This study goes beyond evaluating a given vaccine allocation policy. The proposed approach can be utilized as a decision support tool to prescribe an equitable vaccine allocation policy to extinguish an emerging outbreak in its early stages. Furthermore, the optimal objective function value of our model can inform public health authorities about the amount of vaccine stockpiles needed to stop future outbreaks. Our results indicate that consideration of group-specific transmission dynamics is paramount to the optimal distribution of influenza vaccines.

Shakiba Enayati is an Assistant Professor in Supply Chain and Analytics Department in the College of Business Administration at the University of Missouri- Saint Louis. She earned her Ph.D. in Operations Research Program from North Carolina State University in May 2017. She also holds a Master of Science and a Bachelor in Industrial Engineering from Tarbiat Modares University and Iran University of Science and Technology in Tehran, Iran. She was previously employed as Assistant Professor of Analytics in Management, Information Systems, and Analytics Department at State University of New York, Plattsburgh. Shakiba’s primary research interests are in analytical modeling and optimization of stochastic/dynamic complex systems as applied to healthcare and service systems. Her goal is to address computational and operational aspects of problems arising in public health policy making, health systems management, and medical decision making via incorporating individual patient data. She is also interested in predictive analytics to evaluate, anticipate, and recommend actions for health outcomes at both individual and system levels. Her Ph.D. dissertation focused on service quality improvement and optimally allocating resources in the dynamic and stochastic environment of Emergency Medical Service systems under realistic operational restrictions.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Tue, 10 Nov 2020 16:00:42 -0500 2020-11-16T16:30:00-05:00 2020-11-16T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Shakiba Enayati, Ph.D.
Human Capital, History, Demography & Development (H2D2): Wage Inequality and the Rise in Labor Force Exit: The Case of US Prime-Age Men (November 17, 2020 11:30am) https://events.umich.edu/event/78922 78922-20154732@events.umich.edu Event Begins: Tuesday, November 17, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Mon, 26 Oct 2020 14:05:47 -0400 2020-11-17T11:30:00-05:00 2020-11-17T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Deploying CV2X Infrastructure - CCAT Research Review (November 17, 2020 2:00pm) https://events.umich.edu/event/78766 78766-20121156@events.umich.edu Event Begins: Tuesday, November 17, 2020 2:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

The final CCAT Research Review of 2020 will feature Associate Professor, Gabor Orosz, of the University of Michigan.

The focus of this research is the deployment of connected smart infrastructure on highway I-275 in SE Michigan. Researchers will collect and aggregate traffic information that can be used by connected vehicles traveling the corridor to improve their efficiency. The system consists of a set of road side units (RSU) which collect traffic data via vehicle-to-everything (CV2X) communication. Vehicles of different levels of automation may utilize the collected data when selecting their lane and controlling their longitudinal motion in order to maximize their fuel economy and minimize their travel time. The impact of these vehicles on the rest of the traffic flow is also being evaluated.

About the speaker: Gabor Orosz received the MSc degree in Engineering Physics from the Budapest University of Technology, Hungary, in 2002 and the PhD degree in Engineering Mathematics from the University of Bristol, UK, in 2006. He held postdoctoral positions at the University of Exeter, UK and at the University of California, Santa Barbara. In 2010, he joined the University of Michigan, Ann Arbor where he is currently an Associate Professor in Mechanical Engineering and in Civil and Environmental Engineering. During 2017-2018 he was a Visiting Professor in Control and Dynamical Systems at the California Institute of Technology. His research interests include nonlinear dynamics and control, time delay systems, and reinforcement learning with applications to connected and automated vehicles, traffic flow, and biological networks. He served as the Program Chair of the 2015 IFAC Workshop on Time Delay Systems and served as the General Chair of the 2019 IAVSD Workshop on Dynamics of Road Vehicles: Connected and Automated Vehicles. Since 2018 he has been serving as an editor for the journal Transportation Research Part C.

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Livestream / Virtual Thu, 22 Oct 2020 10:09:41 -0400 2020-11-17T14:00:00-05:00 2020-11-17T15:00:00-05:00 Off Campus Location Center for Connected and Automated Transportation Livestream / Virtual Decorative Image
From Sky Surveys to Cancer: Spatial Data Everywhere (November 18, 2020 3:00pm) https://events.umich.edu/event/78283 78283-20002866@events.umich.edu Event Begins: Wednesday, November 18, 2020 3:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

The talk describes a 25 year journey leading from the Sloan Digital Sky Survey to a wide range of projects in data science. There are many common threads: the need for extreme interactivity, the need for flexible data aggregation and the commonality of spatial data. The size of data sets have grown almost a million fold, but user expectations for almost instant results has not changed. The talk will describe the gradual evolution of the SciServer, and how new interactive metaphors to interact with hundreds of terabytes of turbulence simulations emerged. We will discuss how machine learning and AI tools are transforming science, from simulations to how large experiments are designed and executed. We will also emphasize that much of these new developments still rely on having unique high value data sets at our fingertips, and how the long term survival of these is entering a critical, endangered phase.

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Presentation Fri, 13 Nov 2020 12:16:36 -0500 2020-11-18T15:00:00-05:00 2020-11-18T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation https://umich.zoom.us/j/96874360760
MIPSE Seminar | Lasers, Z Pinches, and Nuclear Weapons: The Importance of Plasma Physics to the NNSA (November 18, 2020 3:30pm) https://events.umich.edu/event/76470 76470-19717163@events.umich.edu Event Begins: Wednesday, November 18, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

About the Speaker:
Dr. Sarah Nelson, a nuclear and radiochemist, is Deputy Director of the Office of Experimental Science for the NNSA Office of Defense Programs. Sarah earned her BS from U. California Santa Barbara and doctorate from U. California Berkeley studying odd-Z transactinide compound nucleus reactions including the discovery of the new isotope 260Bh. Prior to joining NNSA, Sarah was the Roger Batzel Fellow at Lawrence Livermore National Laboratory in nuclear chemistry diagnostic development for NIF and analysis of nuclear systems for domestic counterterrorism applications, co-discovering 14 new transactinide isotopes. Sarah also was selected as a Christine Mirzayan Science & Technology Policy Fellow of The National Academies in 2012. Prior to NNSA, Sarah was also with Pacific Northwest National Laboratory on assignment with the Defense Threat Reduction Agency. She has received numerous awards including the DTRA/US STRATCOM Center for Combatting Weapons of Mass Destruction Director’s Award, LLNL’s Excellence in Publication Award in Basic Science, and the Gordon Battelle Prize for Scientific Discovery.

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Livestream / Virtual Tue, 01 Sep 2020 11:12:17 -0400 2020-11-18T15:30:00-05:00 2020-11-18T16:30:00-05:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Livestream / Virtual Dr. Sarah Nelson
DCMB / CCMB Weekly Seminar (November 18, 2020 4:00pm) https://events.umich.edu/event/79290 79290-20264791@events.umich.edu Event Begins: Wednesday, November 18, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Genetic variation affecting gene expression is wide-spread within and among species. This variation reflects the combined actions of mutation introducing new genetic variants and selection eliminating deleterious ones. Comparative studies of gene expression in fruit flies, yeast, plants, and mice have shown that the relative contributions of cis- and trans-acting variants to expression differences change over evolutionary time, indicating that selection has different effects on cis- and trans-regulatory variants. To better understand the reasons for this now widely observed pattern, we have been systematically studying the effects of mutation and selection on expression of the TDH3 gene of the baker’s yeast Saccharomyces cerevisiae. This work has revealed differences between cis- and trans-regulatory mutations in their frequency, effects, and dominance. Differences in pleiotropy are also generally assumed to exist between cis- and trans-regulatory that affect their evolutionary fate, but have been difficult to measure. In this talk, I will discuss how newly arising cis- and trans-regulatory mutations affecting expression of this focal gene are structured within the regulatory network, their pleiotropic effects on expression of all other genes in the genome, and how these pleiotropic effects influence fitness. A computational model of regulatory evolution integrating empirically observed differences in properties of cis- and trans-regulatory mutations will also be presented and discussed.

Patricia Wittkopp received a BS from the University of Michigan, a PhD from the University of Wisconsin, and did postdoctoral work at Cornell University. In 2005, she began a faculty position at the University of Michigan, where she is now the Sally L. Allen Collegiate Professor and Arthur F Thurnau Professor in the Department of Ecology and Evolutionary Biology and the Department of Molecular, Cellular, and Developmental Biology, and is a member of the Center for Computational Medicine and Bioinformatics. Her research investigates the genetic basis of phenotypic evolution, with an emphasis on the evolution of gene expression. She was a Damon Runyon Cancer Research Fellow, an Alfred P Sloan Research Fellow, Guggenheim Fellow, and a recipient of a March of Dimes Starter Scholar Award, the Margaret Dayhoff Mid-Career Award from the Society of Molecular Biology and Evolution, and the Friedrich Wilhelm Bessel Research Award from the Alexander von Humboldt Foundation.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 09 Nov 2020 15:12:34 -0500 2020-11-18T16:00:00-05:00 2020-11-18T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics: Why does capital flow from equal to unequal countries? (November 18, 2020 4:00pm) https://events.umich.edu/event/79060 79060-20184344@events.umich.edu Event Begins: Wednesday, November 18, 2020 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Capital flows from equal to unequal countries. We document this empirical regularity in a large sample of advanced economies. The capital flows are largely driven by private savings. We propose a theory that can rationalize these findings: more unequal countries endogenously develop deeper financial markets. Households in unequal counties, in turn, borrow more, driving the observed direction of capital flows.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 16 Nov 2020 12:12:16 -0500 2020-11-18T16:00:00-05:00 2020-11-18T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Chemosensory pathways involved in periodontitis and odontogenic pain (November 19, 2020 12:00pm) https://events.umich.edu/event/79190 79190-20225569@events.umich.edu Event Begins: Thursday, November 19, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Marco Tizzano, PhD
Assistant Member, Monell Chemical Senses Center
Adjunct Assistant Professor, Basic & Translational Sciences - Penn Dental Medicine

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Lecture / Discussion Wed, 04 Nov 2020 15:19:42 -0500 2020-11-19T12:00:00-05:00 2020-11-19T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Lecture / Discussion Tizzano
Women + Data Science (November 19, 2020 3:30pm) https://events.umich.edu/event/78621 78621-20075975@events.umich.edu Event Begins: Thursday, November 19, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Michigan State University & University of Michigan invite you to their joint monthly webinar & meetup series for Fall 2020! Please register for access to the Zoom link.

Keynote speaker - Maria Chikina
Lightning talk speakers - Anna Yannakopoulos, MSU | Kayla Johnson, MSU | Stephanie Hickey, MSU

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Presentation Fri, 16 Oct 2020 15:47:06 -0400 2020-11-19T15:30:00-05:00 2020-11-19T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Women + Data Science
BME Seminar Series: Maciek Antoniewicz (November 19, 2020 4:00pm) https://events.umich.edu/event/75911 75911-19623829@events.umich.edu Event Begins: Thursday, November 19, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:25:40 -0400 2020-11-19T16:00:00-05:00 2020-11-19T17:00:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Biophysics Seminar Series (November 20, 2020 12:00pm) https://events.umich.edu/event/77922 77922-20319908@events.umich.edu Event Begins: Friday, November 20, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Gabriele Varani - Department of Chemistry, University of Washington

*"Small drug-like molecules targeting RNA with nanomolar affinity and cellular activityon"*

Join us on Zoom: https://umich.zoom.us/j/99793210061

ABSTRACT: The ever expanding appreciation of the role of RNA in healthy and disease cellular states has created ever increasing opportunities to redress human disease by targeting RNA with small molecules. However, the chemistry of small molecules targeting RNA remains a challenge. The academic literature has been littered since the mid-1990s with reports of small molecules binding to RNA that, in most cases, did not have the pharmaceutical properties of successful drug candidates and did not bind to RNA potently nor specifically. Screening protein-directed chemical libraries allows the discovery of drug-like molecules that bind to RNA, but success rates are low, typically 1/10,000, and affinity typically in the low to mid-uM range. We have discovered RNA-binding small molecules that obey Lipinski and RO5 rules and bind to RNA potently (low to mid nM) and specifically (discriminate single nucleotide changes). These molecules target RNAs considered 'undruggable' with low nM affinity. Their size (<400 Da), absence of charge, and in vitro pharmacological properties (ADME and in vitro pharmacology) are those of favorable drug candidates. We will illustrate two examples of the application of this chemistry by reporting 10 nM ligands for HIV TAR and 100 nM ligands for pre-miR-21 with specific biochemical and cellular activity against this potent oncogene.

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Livestream / Virtual Mon, 16 Nov 2020 13:13:38 -0500 2020-11-20T12:00:00-05:00 2020-11-20T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Gabriele Varani
MCDB Virtual Seminar: Building Functional Neurons with Motors & Microtubules (November 20, 2020 12:00pm) https://events.umich.edu/event/77423 77423-19848085@events.umich.edu Event Begins: Friday, November 20, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Morgan DeSantis

Neurons display an amazing diversity of shapes, sizes and activities. Underlying neuron structure and function is the microtubule cytoskeleton. Microtubules can be stable or highly dynamic, undergoing bouts of growth and shrinkage. We have uncovered a novel a-tubulin mutation that regulates microtubule dynamics, potentially through an effect on acetylation on an uncharacterized site in a-tubulin, and differentially affects the morphology of two distinct neuron types.

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Workshop / Seminar Mon, 16 Nov 2020 15:00:39 -0500 2020-11-20T12:00:00-05:00 2020-11-20T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar drawing of microscope and initials on blue background
Economic Theory: Outside Options and Optimal Bargaining Dynamics (November 20, 2020 2:30pm) https://events.umich.edu/event/81682 81682-20941466@events.umich.edu Event Begins: Friday, November 20, 2020 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We study how to design optimal bargaining strategies in a bargaining model with two players, P and A, when A’s outside option changes over time. We solve for P’s optimal strategy and find a new, but intuitive, set of bargaining dynamics. When A’s outside option increases, A is tempted to cease bargaining, leading P to increase A’s continuation by gradually promising A a larger share of the surplus (decreasing demands) and giving A more time to explore his outside option before being forced to make a decision (decreasing pressure). We explore comparative statics and show that although P ’s value of bargaining is decreasing in A’s outside option, it increases when the expected value of A’s outside option tomorrow rises. We show P’s optimal strategy can be implemented without commitment.

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Workshop / Seminar Wed, 03 Feb 2021 11:59:53 -0500 2020-11-20T14:30:00-05:00 2020-11-20T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Impact of COVID-19 on Service Workers: Work Experiences & Concerns of food retail, food services, and hospitality workers (November 24, 2020 12:00pm) https://events.umich.edu/event/79384 79384-20288598@events.umich.edu Event Begins: Tuesday, November 24, 2020 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Marie-Anne Rosemberg is an assistant professor in UM's School of Nursing.
ABSTRACT
Objectives: COVID-19 presents a unique burden specifically for workers in service industries not only because they are disproportionately at risk for contracting the virus but also because of their work-related burdens. We aimed to understand the impact of COVID-19 on these workers.
Methods: This was a mixed-method study with a congruent triangulation design. Participants were recruited through social media. Each interview lasted up to 20 minutes. The survey data included demographic questions along with items from the CAGE and PC-PTSD questionnaires.
Results: Twenty-seven individuals completed audio-recorded phone interviews and 28 completed the survey. Participants were mostly women with an age range between 19 and 65. Participants worked in food retail (n=23), restaurant (n=25), and hospitality (n=7) industries. Length of time on the job ranged from two months to 25 years and 60% of the participants worked full time. Participants reported experiencing symptoms of depression and maladaptive coping. Job insecurity, change of job tasks, and work hours were the most common ways that COVID-19 affected the workers. Themes that emerged about participant’s concerns included being infected and/or unknowingly infecting others, the unknown, isolation, and work and customer demands. Constant changes relating to communication and protection measures were a major source of stress. There was discordance in the perceived level of threat of COVID-19. Most participants reported that their workplace complied with their state’s mandates for protection measures. While others reported lacking basic supplies such as soap, hand sanitizer, and masks.
Conclusions: In addition to their work experiences, COVID-19 has affected service workers at the financial, physical and mental levels. This study has implications of employers, occupational health and safety professionals and policy stakeholders.

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Lecture / Discussion Thu, 12 Nov 2020 16:33:42 -0500 2020-11-24T12:00:00-05:00 2020-11-24T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Impact of COVID-19 on Service Workers
An Industrial Engineering-Based Approach to Designing and Evaluating Healthcare Systems to Improve Veteran Access to Care (November 30, 2020 4:30pm) https://events.umich.edu/event/79527 79527-20351367@events.umich.edu Event Begins: Monday, November 30, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Access to healthcare is a critical public health issue in the United States, especially for veterans. Veterans are older on average than the general U.S. population and are thus at higher risk for chronic disease. Further, veterans report more delays when seeking healthcare. The Veterans Affairs (VA) Healthcare System continuously works to develop policies and technologies that aim to improve veteran access to care. Industrial engineering methods can be effective in analyzing the impact of such policies, as well as designing or modifying systems to better align veteran patients’ needs with providers and resources.

In the talk, I will focus on veteran access to chronic eye disease screening. Ophthalmologists in the VA have developed a platform in which ophthalmic technicians screen patients for major chronic eye diseases during primary care visits. We use mixed-integer programming-based facility location models to understand how the VA can determine which clinics should offer eye screenings, which provider type(s) should staff those clinics, and how to distribute patients among clinics. The results of this work show how the VA can achieve various objectives including minimizing the cost of treating a given population or maximizing the number of patients receiving care given a fixed budget.

Adam VanDeusen is a PhD candidate in Industrial and Operations Engineering at the University of Michigan working under Dr. Amy Cohn. His work applies operations research and systems engineering methods to public health policy and access to healthcare. As part of his graduate training, Adam works with the University of Michigan Center for Healthcare Engineering & Patient Safety (CHEPS). Adam completed his undergraduate degree in Industrial and Operations Engineering at the University of Michigan and his Master of Public Health in Chronic Disease Epidemiology from Yale School of Public Health. Prior to beginning his PhD, Adam worked as the Senior Director of Clinical Programs at the Health Management Academy and as a Health Systems Engineer at Mayo Clinic.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Fri, 20 Nov 2020 15:23:50 -0500 2020-11-30T16:30:00-05:00 2020-11-30T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Adam VanDeusen
Social, Behavioral & Experimental Economics (SBEE): Loss Attitudes in the U.S. Population: Evidence from Dynamically Optimized Sequential Experimentation (DOSE) (December 1, 2020 10:00am) https://events.umich.edu/event/78715 78715-20107423@events.umich.edu Event Begins: Tuesday, December 1, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
To measure individual-level loss aversion in a representative sample of the U.S. population (N = 2,000), we introduce DOSE—Dynamically Optimized Sequential Experimentation. We find that around 50% of the U.S. population is loss tolerant. This is
counter to earlier findings, which mostly come from lab/student samples, that a strong majority of participants are loss averse. Loss attitudes are correlated with cognitive ability: loss aversion is more prevalent in people with high cognitive ability, and loss tolerance is more common in those with low cognitive ability. We also use DOSE to document facts about risk and time preferences, and demonstrate that DOSE elicitations are more accurate, more stable across time, and faster to administer than standard methods.

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Workshop / Seminar Tue, 20 Oct 2020 17:29:10 -0400 2020-12-01T10:00:00-05:00 2020-12-01T11:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CSCS Seminar | Developing a systematic approach to modulate the emergence of consciousness from pharmacologically-and pathologically induced unconsciousness (December 1, 2020 11:30am) https://events.umich.edu/event/76220 76220-19677552@events.umich.edu Event Begins: Tuesday, December 1, 2020 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

ZOOM MEETING LINK: myumi.ch/v2ZYv

Re-scheduled from earlier this fall.

ABSTRACT:
Why is it so difficult to develop a systematic approach to modulate the recovery of consciousness from pharmacologically and pathologically induced unconsciousness? Three things are required to develop a systematic approach; a reliable neural activity that corresponds to consciousness, a reliable brain stimulation to induce the target neural activity, and a mechanism to guarantee the induced neural activity results in consciousness. However, no single neural activity or a mechanism has been identified yet as a neural correlate of consciousness, suggesting that consciousness might emerge through complex interactions of spatially and temporally distributed brain functions. Accumulating evidence from computational model and empirical studies suggest that brain criticality – a balanced state between order and disorder, stability and instability, incoherent and synchronized connectivity at a global network level, is a necessary condition for the emergence of consciousness. Thus, in our research project, we hypothesized that with modulating brain network criticality, we may be able to control the state transition during the loss and recovery of consciousness in general anesthesia and coma. In this talk, I will introduce our current project that aims to develop a systematic method to precisely evaluate a brain state in altered states of consciousness and to control the emergence from unconsciousness, which is based on highly advanced methods in physics, network science, and neurobiology of consciousness.

Please join us 15 minutes before and after the seminar for a social coffee hangout. Put your speakers and video on and say hi to old friends or go to the 'lounge' and chat with an acquaintance

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Livestream / Virtual Mon, 23 Nov 2020 16:33:23 -0500 2020-12-01T11:30:00-05:00 2020-12-01T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Photo of UnCheol Lee
Human Capital, History, Demography & Development (H2D2): Combating COVID-19: Measuring and Changing Beliefs, Knowledge, and Behaviors - Part 2 (December 1, 2020 11:30am) https://events.umich.edu/event/78925 78925-20154734@events.umich.edu Event Begins: Tuesday, December 1, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Tue, 17 Nov 2020 17:23:48 -0500 2020-12-01T11:30:00-05:00 2020-12-01T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIPSE Seminar | Exploring Transformative Startup Solutions for Magnetically Confined Fusion Plasmas (December 2, 2020 3:30pm) https://events.umich.edu/event/76473 76473-19717165@events.umich.edu Event Begins: Wednesday, December 2, 2020 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

Abstract:
The potential to use fusion as a carbon-free, fuel-abundant energy source to meet the world’s growing energy demands has motivated significant US and international research. One research path to realize fusion energy involves tokamaks that magnetically confine hot plasmas in the shape of a torus. Almost every tokamak fusion reactor in the world relies on magnetic induction from a central solenoid to drive the current necessary to create a fusion grade plasma. Minimizing or eliminating the need for a central solenoid in a tokamak would greatly simplify the construction and reduce the cost of these devices, increasing their viability for commercial energy production. Solenoid-free startup techniques such as helicity injection (HI) and radiofrequency (RF) wave injection offer the potential of reducing the technical requirements of, or possibly the need for, a central solenoid. A major upgrade is underway for the spherical tokamak, Pegasus-III at the U of Wisconsin. The new facility will be a dedicated US platform to study innovations in plasma startup techniques, allowing for studies of both HI and RF during plasma initiation, ramp-up and sustainment. Experimental plans for RF heating and current drive in the microwave regime will be presented. The new capabilities of Pegasus-III will provide a bold test of the viability of a non-solenoidal compact tokamak using reactor relevant techniques.

About the Speaker:
Prof. Diem’s research interests are in experimental plasma physics for fusion energy development with emphasis on validating numerical models with experimental data. She focuses on utilizing radio frequency (RF) waves to heat and drive current in magnetically confined plasmas. Prof. Diem’s current research is focused on electron Bernstein wave and electron cyclotron heating and current drive experiments on Pegasus-III at UW-Madison as well as collaborations domestically and internationally on RF injection in magnetically confined fusion plasmas. Prof. Diem received her PhD in Plasma Physics from Princeton U. where she developed diagnostics to study electron Bernstein wave emission and mode conversion on the National Spherical Tokamak at the Princeton Plasma Physics Lab. She received a BS in Nuclear Engineering & Engineering Physics from UW-Madison. Prior to joining the faculty at UW-Madison, Prof. Diem was a Research and Development Staff Scientist in the Fusion Energy Division at Oak Ridge National Lab. and was on long-term assignment at the DIII-D National Fusion Facility at General Atomics in San Diego, CA.

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Livestream / Virtual Tue, 01 Sep 2020 11:32:57 -0400 2020-12-02T15:30:00-05:00 2020-12-02T16:30:00-05:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Livestream / Virtual Prof. Stephanie Diem
DCMB / CCMB Weekly Seminar (December 2, 2020 4:00pm) https://events.umich.edu/event/79631 79631-20436379@events.umich.edu Event Begins: Wednesday, December 2, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

ABSTRACT: The brain is made of networks of neurons that send information to each other via spikes. Sleep and wake are the most clearly definable brain states and each exerts unique effects upon neural network spiking activity. We used large-scale recordings in the frontal cortex of mice and rats to examine the activity of neurons during wake/sleep cycles and found that a novel form of homeostatic action is taken by sleep: homogenization of firing rates. Whereas it was previously believed that sleep simple decreased firing rates, we found that this was much more true of the most active neurons only, thereby reducing the variance of the population.

To extend this observation of homeostatic forced during sleep we also examine how sleep and wake states interact with learning and performance, which is also facilitated by sleep. We have therefore begun to record before, during and after learning sessions to determine how learning interacts with the usual homeostatic effects of sleep. Further we can also record how waking changes in brain states such as motivation and attention modulate firing and information processing by neurons during behavior itself.

Finally, our end-goal to translate these kinds of basic neurobiologic observations in healthy rodents to states of stress or treatments of stress. Unfortunately the chronic stress states of relevance to psychiatric disease do not last seconds but days and weeks. We have therefore begun to build new long-term recording environments to enable future experiments over these time-spans.

BIOGRAPHY:
Dr. Watson is an assistant professor in psychiatry at the University of Michigan. He grew up in Ann Arbor and then obtained his BA from Cornell University and his M.D. and Ph.D. degrees from Columbia University. During his Ph.D. he used two-photon microscopy to study the behavior of neurons in local cortical microcircuits. During his doctoral work he also participated in technical development of multi-beam two photon imaging techniques. Upon graduation from medical school, Dr. Watson pursued a residency in Psychiatry at Weill Cornell Medical College as well postdoctoral work at New York University. He received the National Institute for Mental Health’s Outstanding Resident Award, the American Psychiatric Association’s Lilly Research Fellowship and the Leon Levy Neuroscience Fellowship. He did a fellowship with Dr. Gyorgy Buzsaki at NYU to record ongoing activity in naturally behaving and sleeping animals wherein he showed that sleep reorganizes neuronal firing architecture in the neocortex in previously unknown ways. He is now combining his electrical recordings with behavioral tools to deepen his understanding of both use and regulation of cortical brain circuits.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Tue, 01 Dec 2020 09:45:44 -0500 2020-12-02T16:00:00-05:00 2020-12-02T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics (December 2, 2020 4:00pm) https://events.umich.edu/event/79061 79061-20184345@events.umich.edu Event Begins: Wednesday, December 2, 2020 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 09 Nov 2020 17:19:16 -0500 2020-12-02T16:00:00-05:00 2020-12-02T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
“Mesenchymal Regulation of Tooth Root Formation and Eruption” (December 3, 2020 12:00pm) https://events.umich.edu/event/79611 79611-20430435@events.umich.edu Event Begins: Thursday, December 3, 2020 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Wanida Ono, PhD
Assistant Professor, Orthodontics and Pediatric Dentistry
University of Michigan School of Dentistry

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Workshop / Seminar Mon, 30 Nov 2020 14:32:33 -0500 2020-12-03T12:00:00-05:00 2020-12-03T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Workshop / Seminar Ono
BME Seminar Series: Jae-Won Shin (December 3, 2020 4:00pm) https://events.umich.edu/event/75912 75912-19623830@events.umich.edu Event Begins: Thursday, December 3, 2020 4:00pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Join us for our virtual seminar series on Thursdays from 4-5pm!
These events will take place on BlueJeans at this link: https://bluejeans.com/628109990

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Workshop / Seminar Thu, 20 Aug 2020 14:28:28 -0400 2020-12-03T16:00:00-05:00 2020-12-03T17:00:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME
Statistics Department Seminar Series: Yinqiu He, PhD Candidate, Department of Statistics, University of Michigan (December 4, 2020 10:00am) https://events.umich.edu/event/79568 79568-20382970@events.umich.edu Event Begins: Friday, December 4, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract:
In scientific research that involves large-scale data, researchers often start with questions regarding the global properties of a large set of measurements. For instance, are a group of related genes in the same functional pathway jointly associated with a trait of interest? Such questions can be formulated as hypothesis testing problems that globally examine a large number of parameters in a high-dimensional joint distribution. Examples include hypothesis testing on mean vectors, covariance matrices and regression coefficients. To extract informative scientific knowledge from abundant data, reliability and efficiency are among the major concerns in statistical inference.

In this talk, I will address particular reliability and efficiency issues arising from jointly testing a large number of parameters. First, I will discuss how reliable the popular likelihood ratio tests (LRTs) are in terms of the type I error control for high-dimensional data. I will present statistically principled guidelines on the reliability of the LRTs in a variety of problems, which are based on phase transition results of the foundational Wilk’s theorem. Next, to improve efficiency of the existing testing procedures under high-dimensional settings, I will introduce a new adaptive testing framework that can maintain high statistical power against a wide range of alternative hypotheses. The proposed framework is based on a family of U-statistics that are constructed to capture the information in different directions in high-dimensional spaces. For a broad class of problems, we establish high-dimensional asymptotic theory for the U-statistics and develop adaptive testing procedures that are statistically powerful in a wide variety of scenarios.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow.

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Workshop / Seminar Tue, 24 Nov 2020 15:18:56 -0500 2020-12-04T10:00:00-05:00 2020-12-04T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Yinqiu He
Biophysics Seminar Series (December 4, 2020 12:00pm) https://events.umich.edu/event/77923 77923-19941588@events.umich.edu Event Begins: Friday, December 4, 2020 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Oleg Igoshin - Professor of Bioengineering & BioSciences, Associate Chair of Bioengineering, Rice University

*“Understanding Trade-offs in Biological Error Correction”*

Join us on Zoom: https://umich.zoom.us/j/96475935279

Abstract: High accuracy of major biological processes relies on the ability of the participating enzymatic molecules to preferentially select the correct substrate from a pool of chemically similar substrates by activating the so-called proofreading mechanisms. While the importance of such mechanisms is widely accepted, it is still unclear how evolution has optimized the biological systems with respect to their characteristic properties. We developed a comprehensive first-passage theoretical framework that allowed us to quantitatively investigate the trade-offs between four properties of enzymatic systems namely, error, speed, noise and energy dissipation. Within this framework, we simultaneously analyzed speed and accuracy of several fundamental biological processes, including DNA replication, tRNA charging, and tRNA selection during the translation. The results indicate that contrary to typical assumptions speed-accuracy trade-off is not always observed. However, when the trade-off is present, the biological systems tend to optimize the speed rather than the accuracy of the processes, as long as the error level is tolerable. When systems function in the regime where no speed-accuracy trade-off is observed, constraints due to energy dissipation in the proofreading play a key role. Our theory demonstrates a universal Pareto front in error-dissipation trade-off and shows how naturally selected kinetic parameters position their system close to this boundary. Our findings, therefore, provide a new system-level picture of how complex biological processes are able to function so fast with a high accuracy and low dissipation.

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Livestream / Virtual Tue, 01 Dec 2020 08:40:21 -0500 2020-12-04T12:00:00-05:00 2020-12-04T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Igoshin
MCDB Virtual Seminar: Receptors, channels and animal behavior (December 4, 2020 12:00pm) https://events.umich.edu/event/72767 72767-19848086@events.umich.edu Event Begins: Friday, December 4, 2020 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Bo Duan

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Workshop / Seminar Mon, 26 Oct 2020 14:45:08 -0400 2020-12-04T12:00:00-05:00 2020-12-04T14:00:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar MCDB initials & microscope drawing in yellow on a blue square
Cognitive Science Seminar: "Cognitive Tools for Learning and Communication" (virtual) (December 7, 2020 2:30pm) https://events.umich.edu/event/76965 76965-19782527@events.umich.edu Event Begins: Monday, December 7, 2020 2:30pm
Location: Off Campus Location
Organized By: Weinberg Institute for Cognitive Science

Dr. Judith Fan, Assistant Professor in the Department of Psychology, UC San Diego, will give a talk titled "Cognitive Tools for Learning and Communication."

ABSTRACT

How does the human mind transform a cascade of sensory information into meaningful knowledge? While traditional approaches to learning focus on how people process the data provided to them by the world, this approach leaves aside all of the powerful tools people have to actively reformat their experiences and generate new ones. For example, we choose what to look at, bring certain memories to mind, produce pictures to share, and compose stories to tell. The goal of our lab’s research is to “reverse engineer” the core mechanisms by which employing such cognitive tools enable humans to learn and communicate more effectively. Our recent work focuses on visual communication, one of our most basic and versatile tools, because it also represents a key challenge for understanding how multiple cognitive systems interact to support complex, natural behaviors. This talk will highlight our recent progress, as well as open research questions in this domain.

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Livestream / Virtual Mon, 07 Dec 2020 11:22:51 -0500 2020-12-07T14:30:00-05:00 2020-12-07T16:00:00-05:00 Off Campus Location Weinberg Institute for Cognitive Science Livestream / Virtual Judith Fan
Forecasting and Stochastic Programming Models to Address Uncertainty in the Trauma System Configuration Problem (December 7, 2020 4:30pm) https://events.umich.edu/event/79689 79689-20454252@events.umich.edu Event Begins: Monday, December 7, 2020 4:30pm
Location: Off Campus Location
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Trauma care services are a vital part of all healthcare-based network as timely accessibility is important for citizens. Trauma care access is even more relevant when unexpected events such as the COVID-19 pandemic overload the capacity of the hospitals. Research literature has highlighted that access to trauma care is not even for all populations, especially when comparing rural and urban groups. Historically, the configuration of a trauma system was often not considered as a whole but instead hinged on the designation and verification of individual hospitals as trauma care centers. Recognition of the benefits of an inclusive trauma system has precipitated a more holistic approach. The optimal geographic configuration of trauma care centers is key to maximizing accessibility while promoting the efficient use of resources. This talk focuses on analyzing and forecasting physical trauma sustained from accidents, in environments both personal and work related, pertaining to individual injuries and to formulate a stochastic programming model that utilizes recorded injuries as demands to place trauma centers in the most optimal location. The first part of the talk discusses the limitations faced by the existing trauma healthcare infrastructure by forecasting the expected number of people requiring the services of trauma facilities for both rural and urban locations in Texas. Five types of forecasting methods were analyzed to determine the best option to utilize for forecasting for individual data sets. The aim is to identify which forecasting model performs the best for given data sets that can be used to forecast patient demand for a given location and determine the optimal locations for trauma network expansion. The second part of the talk reports on the development of a two-stage stochastic optimization model for geospatial expansion of a trauma network in the state of Texas. The stochastic optimization model recommends the siting of new trauma care centers according to the geographic distribution of the injured population. The model has the potential to benefit both patients and institutions, by facilitating prompt access and promoting the efficient use of resources.

Eduardo Pérez is an Associate Professor in the Ingram School of Engineering at Texas State University. He was a Postdoctoral Research Associate in the Department of Industrial and Systems Engineering at Texas A&M University from 2010 to 2012. He received his PhD in Industrial and Systems Engineering from Texas A&M University in 2010 and his B.S. in Industrial Engineering from the University of Puerto Rico at Mayagüez, Puerto Rico in 2004. Dr. Pérez’s research interests are in the use of methodologies and theories in operations research, systems engineering, discrete-event simulation, algorithms and software design, and decision theory analysis to solve problems in service systems. Some of his research project sponsors include the National Science Foundation (NSF), the Department of Homeland Security (DHS), the Robert Wood Johnson Foundation, Baylor Scott & White Health System, Adventist Health System, and the NEC Corporation. Dr. Eduardo Pérez is a member of the Institute of Industrial Engineers (IIE), the Institute for Operations Research and Management Sciences (INFORMS), and the Society for Computer Simulation International (SCS). He received his Engineering-In-Training (EIT) certification in 2004. He is the director of the Integrated Modeling and Optimization for Service Systems (iMOSS) research laboratory.

For a full listing of our Fall 2020 seminars, see https://cheps.engin.umich.edu/seminar-series/2020-seminar/

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach.
For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP.
For additional questions, contact CHEPSseminar@umich.edu.
Photographs, screen captures, and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 03 Dec 2020 15:50:46 -0500 2020-12-07T16:30:00-05:00 2020-12-07T17:30:00-05:00 Off Campus Location Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Eduardo Pérez, Ph.D.
Social, Behavioral & Experimental Economics (SBEE): Collaborative Dishonesty: A Meta-Study (December 8, 2020 10:00am) https://events.umich.edu/event/78687 78687-20105422@events.umich.edu Event Begins: Tuesday, December 8, 2020 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Whereas dishonesty is often a result of collaborative efforts, it is commonly studied in individual settings. We present the first meta-study on collaborative dishonesty, reviewing 51,640 decisions, made by 3,264 individuals. Results reveal that people are influenced by their partners’ lies: They lie more (i) in collaborative than in individual settings, (ii) when their partners lie, and (iii) in later stages of the interaction.

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Workshop / Seminar Tue, 20 Oct 2020 11:04:37 -0400 2020-12-08T10:00:00-05:00 2020-12-08T11:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Human Capital, History, Demography & Development (H2D2): The Impact of Trade on Development: Evidence from Pastoralist Practices on the Ancient Silk Road/ Effects of Paid Family Leave on Older Adults (December 8, 2020 11:30am) https://events.umich.edu/event/78923 78923-20154733@events.umich.edu Event Begins: Tuesday, December 8, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Tue, 17 Nov 2020 17:25:09 -0500 2020-12-08T11:30:00-05:00 2020-12-08T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Department of Computational Medicine & Bioinformatics Weekly Wednesday Seminar (December 9, 2020 4:00pm) https://events.umich.edu/event/79756 79756-20484062@events.umich.edu Event Begins: Wednesday, December 9, 2020 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Learning objectives:

1. Discuss the conceptual distinction and clinical utility of self-reported race/ethnicity and genetic ancestry in childhood asthma.
2. Discuss the role of genetic ancestry and socio-environmental exposures in childhood asthma.
3. Discuss ancestry-specific polygenic risk scores, precision medicine and childhood asthma disparities.

Short bio: Dr. Mersha is currently an Associate Professor in the Division of Asthma Research and leads the Population Genetics, Ancestry, and Bioinformatics (pGAB) Laboratory (https://research.cchmc.org/mershalab/Home.php).
Dr. Mersha’s research combines quantitative, ancestry and statistical genomics to unravel genetic and non-genetic contributions to complex diseases and racial disparities in human populations, particularly asthma and asthma-related allergic disorders. Much of his research is at the interface of genetic ancestry, statistics, bioinformatics, and functional genomics, and he is interested in cross-line disciplines to unravel the interplay between genome and envirome underlying asthma risk. His long-term research goal is to understand and dissect how biologic predisposition and environmental exposures interact to shape racial disparities in complex disorders.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 07 Dec 2020 11:27:42 -0500 2020-12-09T16:00:00-05:00 2020-12-09T17:15:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Tesfaye ("Tes") Mersha, PhD (Associate Professor, Division of Asthma Research at Cincinnati Children's Hospital Medical Center)
Human Capital, History, Demography & Development (H2D2): Income Effects in Early Childhood/ Do Urgent Care Centers Increase Access to Care and Decrease Healthcare Costs? (December 15, 2020 11:30am) https://events.umich.edu/event/78926 78926-20154735@events.umich.edu Event Begins: Tuesday, December 15, 2020 11:30am
Location: Off Campus Location
Organized By: Department of Economics

To join the seminar, please visit the following webpage.
https://sites.google.com/view/h2d2/seminars

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Workshop / Seminar Mon, 26 Oct 2020 14:17:39 -0400 2020-12-15T11:30:00-05:00 2020-12-15T12:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Data Science Coast to Coast Presents: Dr. Jeanne Holm (December 15, 2020 3:00pm) https://events.umich.edu/event/78800 78800-20125167@events.umich.edu Event Begins: Tuesday, December 15, 2020 3:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

The DS C2C seminar series, hosted jointly by six academic data science institutes, provides a unique opportunity to foster a broad-reaching data science community.

This fall, the series features important figures in data science, who will provide insight on the transformative use of data science in traditional research disciplines, future breakthroughs in data science research, data science entrepreneurship, and advocacy and national policies for a data-enabled and just society.

Speakers throughout the winter and spring will include faculty members and postdoctoral fellows at the six universities whose research spans the theory and methodology of data science, and their application in arts and humanities, engineering, biomedical, natural, physical and social sciences.

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Presentation Thu, 22 Oct 2020 23:08:05 -0400 2020-12-15T15:00:00-05:00 2020-12-15T16:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Data Science: Coast 2 Coast
THE CHANGING LANDSCAPE OF BIOMEDICAL DATA COLLECTIONS (December 21, 2020 4:00pm) https://events.umich.edu/event/79454 79454-20327789@events.umich.edu Event Begins: Monday, December 21, 2020 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Abstract:

The landscape of biomedical data is incredibly complex, rich, and rapidly changing, especially as we navigate the influx of data from the COVID-19 pandemic. More and more data is moving to the cloud, both existing and newly generated, with multiple cloud providers adding to the complexity. The data includes Electronic Health Records (EHRs), genomic data, and imaging/sensed data (e.g., pictures of tumors, lungs, cells, gas chromatographs), and all this data is enabling us to delve much deeper into complex biological concepts, for example, the relationship between phenotypes and genotypes. The NHLBI BioData Catalyst project is one example of a coordinated effort to move vast amounts of data into the cloud, navigating the complexities of data ingestion, diverse and widespread teams, and multiple cloud providers/environments.

On top of the massive shift to being able to apply huge amounts of data to better understand individuals, populations and, ultimately, life itself, we need a way to organize all this information. The activities in the NCATS Biomedical Data Translator project can be viewed as a constantly evolving analysis of the relationships of disparate data sets. In a sense, Translator is like Google for searching biomedical data.

My talk will introduce both projects and their respective impacts on biomedical research.

Bio:

Dr. Stan Ahalt is the Director of the Renaissance Computing Institute (RENCI) at UNC-Chapel Hill. As Director, he leads a team of research scientists, software and network engineers, data science specialists, and visualization experts who work closely with faculty research teams at UNC, Duke, NCSU, and partners across the country. Dr. Ahalt is also a Professor in UNC’s Department of Computer Science and the Associate Director of Informatics and Data Science (IDSci) in the North Carolina Translational and Clinical Sciences Institute (NC TraCS), UNC’s CTSA award; in this role, Dr. Ahalt leverages the expertise and resources of RENCI to foster clinical and translational research across UNC’s campus. Dr. Ahalt earned his Ph.D. in Electrical and Computer Engineering from Clemson University and has over 30 years of experience in data science, signal and image processing, and pattern recognition/ML.

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Presentation Mon, 23 Nov 2020 12:01:11 -0500 2020-12-21T16:00:00-05:00 2020-12-21T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Stan Ahalt
Social, Behavioral & Experimental Economics (SBEE): Social Learning in Groups: an Experimental Study (January 13, 2021 1:00pm) https://events.umich.edu/event/79776 79776-20491896@events.umich.edu Event Begins: Wednesday, January 13, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
A large literature in economics and finance has shown the dangers associated with — and the inefficiencies that arise from — the imitation of others’ actions, and from herd behavior in particular. We contribute to this literature by providing empirical evidence of the benefits of imitation in repeated social learning environments. We show experimentally that observing the actions of others improves the quality of decisions and leads to higher information aggregation rates, even in settings where the actions of others do not provide additional information, beyond the private information available to agents.
Specifically, we conduct a series of controlled laboratory experiments, in which subjects repeatedly try to estimate an unknown state of nature while observing private information that arrives sequentially, and, depending on the treatment, additional observations of others. There are no direct externalities in this setting, and each subject is rewarded independently of others for estimating correctly. Between treatments, we vary the information available to subjects at the time they make their guesses. This simple setting allows us to address two questions. First, we document whether at all and to what extent people are capable of extracting the information contained in their peers’ private signals by observing their actions, in a repeated setting. Second, we study the usefulness of observing other people’s decisions when private signals of others are also available, and, thus, others' actions should be irrelevant.

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Workshop / Seminar Tue, 08 Dec 2020 09:10:32 -0500 2021-01-13T13:00:00-05:00 2021-01-13T14:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Biophysics Seminar Series (January 15, 2021 12:00pm) https://events.umich.edu/event/80417 80417-20719670@events.umich.edu Event Begins: Friday, January 15, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Michele Vendruscolo - Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge

*“Activity Relationship by Kinetics for Drug Discovery in Protein Misfolding Diseases”*

ABSTRACT: Protein oligomers are increasingly recognized as the most cytotoxic forms of protein aggregates. It has been very challenging, however, to target these oligomers with therapeutic compounds, because of their dynamic and transient nature. To overcome this problem, I will describe a 'structure kinetic-activity relationship' (SKAR) approach, which enables the discovery and systematic optimization of compounds that reduce the number of oligomers produced during an aggregation reaction. I will illustrate this strategy for the amyloid beta peptide, which is closely associated with Alzheimer's disease, by developing a rhodanine compound capable of dramatically reducing the production of amyloid beta oligomers. As this strategy is general, it can be applied to oligomers of any protein.

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Livestream / Virtual Wed, 06 Jan 2021 10:17:32 -0500 2021-01-15T12:00:00-05:00 2021-01-15T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Michele Vendruscolo
U-M Health Sciences 2021 MLK Keynote (January 18, 2021 12:00pm) https://events.umich.edu/event/79757 79757-20484063@events.umich.edu Event Begins: Monday, January 18, 2021 12:00pm
Location: Off Campus Location
Organized By: School of Kinesiology

Bodies represent the sites of socially constructed differences and power relations. As such, the personal is political, and bodies are subject to political interpretations. Body politics based on racial (and/or ethnic) ascriptions (along with other intersecting elements such as sex, gender, sexuality, age, social class, ability, etc.) have adversely affected the overall health and wellness of bodies of Color in general, and Black bodies in particular - impacting their abilities, opportunities, access (inclusion/exclusion), care/treatment, and the overall nature of their lived experiences. Consequently, racialed body politics have contributed to an array of health disparities being more pronounced in communities of Color. However, movement offers a variety of health benefits and is therefore, a source of empowerment for racially politicized bodies.

This event will feature a keynote presentation by Dr. Monique Butler, U-M Kinesiology alumna and Chief Medical Officer for HCA Healthcare North Florida Division. She will address the theme "Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment."

This event is sponsored by the U-M Health Sciences units and hosted by the School of Kinesiology.

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Lecture / Discussion Tue, 05 Jan 2021 16:27:06 -0500 2021-01-18T12:00:00-05:00 2021-01-18T13:30:00-05:00 Off Campus Location School of Kinesiology Lecture / Discussion U-M Health Sciences 2021 MLK Keynote - Where Do We Go From Here: Body Politics and Movement Towards Racial Empowerment - with Dr. Monique Butler, MD
Social, Behavioral & Experimental Economics (SBEE): The Misallocation of Women’s Talent Across Countries: Evidence from Personnel Data (Ashraf, Bandiera, Minni, Quintas-Martinez) (January 20, 2021 1:00pm) https://events.umich.edu/event/80593 80593-20759751@events.umich.edu Event Begins: Wednesday, January 20, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Women labor force participation varies widely: in Pakistan one worker in five is a woman, in Sweden every other worker is. We study the effect of these differences on the misallocation of talent. To do so we first show that selection into the labor force is positive, namely, the hgiher the barrier the more able the women who work and then use personnel data of a global MNE to estimate a structural model of pay setting within the firm, allowing the parameters to respond to local conditions. We show that the average ability of women in the workforce is higher than men’s and the ratio is largest where LFP is lower. We quantify the role of social norms and discuss policy alternatives

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Fri, 15 Jan 2021 09:17:03 -0500 2021-01-20T13:00:00-05:00 2021-01-20T14:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Statistics Department Seminar Series: Ying Cheng, Professor of Psychology, University of Notre Dame (January 22, 2021 10:00am) https://events.umich.edu/event/80504 80504-20730284@events.umich.edu Event Begins: Friday, January 22, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Quality control in assessment is of critical importance to ensure the reliability and validity of the scores produced by assessments, and the replicability and reproducibility of research findings. In this talk I will cover various aspects of quality control in high-stakes and low-stakes assessment scenarios. One specific problem will be discussed in detail, i.e., the detection of unintended intra-individual change during the assessment process, such as test speededness and item pre-knowledge in the high-stakes context and respondent disengagement in the low-stakes context. By bringing the traditional statistical quality control methods including change point analysis and CUSUM control chart into the framework of item response theory (IRT) modeling, new methods are developed to detect such response anomalies and protect validity of assessment scores.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow

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Workshop / Seminar Wed, 20 Jan 2021 14:25:47 -0500 2021-01-22T10:00:00-05:00 2021-01-22T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Ying Cheng
Biophysics Seminar Series (January 22, 2021 12:00pm) https://events.umich.edu/event/80727 80727-20777543@events.umich.edu Event Begins: Friday, January 22, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Katrin Heinze - Rudolf Virchow Center for Integrative and
Translational Bioimaging, Universität Würzburg

*“Boosting high-resolution fluorescence by tunable nano-coatings"*

ABSTRACT: The “Resolution Revolution" in fluorescence microscopy over the last decades has given rise to a variety of techniques that allow imaging beyond the diffraction limit with resolution up to the nanometer range. One particularly powerful technique is direct stochastic optical
reconstruction microscopy (dSTORM), a widely-used type of single molecule localization microscopy (SMLM), which is based on the temporal separation of the emission of individual fluorophores
and subsequent localization analysis. This eventually allows to reconstruct a super-resolved image revealing details down to typically 20 nm in a cellular setting. The key point here is the achievable localization precision, which mainly depends on the image contrast generated by the individual fluorophore’s emission. We found that reflective metal-dielectric nano-coatings represent a tunable nanomirror that can do both quenching and boosting fluorescence for high-contrast imaging on the nanoscale. Such mirror-enhanced fluorescence is very different from other surface effects based on total internal reflection microscopy or optoplasmonics. While surface-plasmon supported fluorescence methods provide much higher enhancement factors, mirror-enhanced approaches are more versatile and thus highly suitable for modern bio-imaging. The resolution improvement achieved with such mirror-enhanced STORM (meSTORM) is both spectrally and spatially tunable and thus allows for dual-color approaches on the one hand, and selectively highlighting region above the cover glass on the other hand. Even if the resulting resolution boost is based on a near-field effect and thus restricted to imaging near surfaces, a large variety of membrane fluorescence approaches even beyond SMLM benefit. Thus, live-cell
Fluorescence Correlation Spectroscopy and Fluorescence Resonance Energy Transfer are as well perfect candidates to be pushed to the next level.

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Livestream / Virtual Wed, 13 Jan 2021 15:37:36 -0500 2021-01-22T12:00:00-05:00 2021-01-22T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Katrin Heinze
Environmental Health Priorities in Southeast Michigan (January 26, 2021 12:00pm) https://events.umich.edu/event/80220 80220-20601996@events.umich.edu Event Begins: Tuesday, January 26, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

The Integrated Health Sciences Core (IHSC) of M-LEEaD kicks off the first in a series on community engaged research with a presentation by the Community Engagement Core (CEC) and its Stakeholder Advocacy Board (SAB). Members of the CEC and SAB will share an overview of environmental health priorities in Southeast Michigan, ongoing efforts to address them, and new opportunities for M-LEEaD affiliated researchers. This "Meet and Learn" will focus on the purpose and objective of the CEC and how these relate to the NIEHS core objectives. Please join us!

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Lecture / Discussion Tue, 22 Dec 2020 10:12:52 -0500 2021-01-26T12:00:00-05:00 2021-01-26T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Jan 26 Environmental Priorities in SE Michigan
Social, Behavioral & Experimental Economics (SBEE): Identity and Underrepresentation: Interactions between Race and Gender (with Bary Pradelski) (January 27, 2021 1:00pm) https://events.umich.edu/event/80368 80368-20711697@events.umich.edu Event Begins: Wednesday, January 27, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Economic outcomes vary significantly across socio-demographic groups. In a model
of multi-dimensional identity, we show how economic underrepresentation can evolve
through identity-specific norms. Whereas standard approaches treat identity dimensions as independent, our analysis reveals deep connections between inequality and underrepresentation based on race, gender and other characteristics. `Sterilized interventions' along a single identity dimension are impossible. Interventions that aim to reduce underrepresentation along one identity dimension can increase underrepresentation along another. We show how underrepresentation can be eliminated along every dimension, through a system of (a) self- financing subsidies or (b) role models, where interventions are connected across identity dimensions.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Fri, 15 Jan 2021 09:23:41 -0500 2021-01-27T13:00:00-05:00 2021-01-27T14:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Department of Computational Medicine & Bioinformatics Seminar (January 27, 2021 4:00pm) https://events.umich.edu/event/80722 80722-20777538@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Massively parallel single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened the way to systematic tissue atlases in health and disease, but as the scale of data generation is growing, so is the need for computational pipelines for scaled analysis. We developed Cumulus, the first comprehensive cloud-based framework, to address the big data challenge arising from sc/snRNA-seq analysis. Cumulus combines the power of cloud computing with improvements in algorithm and implementation to achieve high scalability, low cost, user-friendliness and integrated support for a comprehensive set of features. We benchmark Cumulus on the Human Cell Atlas Census of Immune Cells dataset of bone marrow cells and show that it substantially improves efficiency over conventional frameworks, while maintaining or improving the quality of results, enabling large-scale studies.

In recent years, biologists have found that sc/snRNA-seq alone is not enough to reveal the full picture of how cells function and coordinate with each other in a complex tissue. They begin to couple sc/snRNA-seq with other common data modalities, such as single-cell ATAC-seq (scATAC-seq), single-cell Immune Repertoire sequencing (scIR-seq), spatial transcriptomics and mass cytometry. This data coupling is called single-cell multimodal omics. As it is becoming a new common practice, new analysis needs emerge along with two major computational challenges: big data challenge and integration challenge. The big data challenge requires us to develop scalable computational infrastructure and algorithms to deal with the ever-growing large datasets produced from the community. The integration challenge requires us to design new algorithms to enable holistic integration of heterogeneous data from different modalities. In the last part of my talk, I will discuss my team’s efforts and plans to develop Cumulus as an integrated data analysis framework for scaled single-cell multimodal omics.

Single-cell multimodal omics has the potential to provide a more comprehensive characterization of complex multicellular systems than the sum of its parts. As the datasets produced from the community keep growing substantially, the enhanced Cumulus will continue playing an important role in the effort to build atlases of complex tissues and organs at higher cellular resolution, and in leveraging them to understand the human body in health and disease.

Short bio: Dr. Bo Li is an assistant professor of medicine at Harvard Medical School, the director of Bioinformatics and Computational Biology at Center for Immunology Inflammatory Diseases, Massachusetts General Hospital, and an associate member of the Broad Institute of MIT and Harvard. His research focuses on large-scale single-cell and single-nucleus genomics data analysis. He received his Ph.D. in computer science from UW-Madison and completed two postdoctoral trainings with Dr. Lior Pachter at UC Berkeley and Dr. Aviv Regev at Broad Institute. He is best known for developing RSEM, an impactful RNA-seq transcript quantification software. RSEM is cited 9,384 times (Google Scholar) and adopted by several big consortia such as TCGA, ENCODE, GTEx and TOPMed.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 13 Jan 2021 14:32:34 -0500 2021-01-27T16:00:00-05:00 2021-01-27T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Bo Li, PhD (Assistant Professor at Harvard Medical School in Boston, MA)
Michael Beauregard Seminar in Macroeconomics: Regulating Conglomerates: Evidence from an Energy Conservation Problem in China (January 27, 2021 4:00pm) https://events.umich.edu/event/81233 81233-20877905@events.umich.edu Event Begins: Wednesday, January 27, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
How does energy regulation affect production and energy use within conglomerates? We study the effects of a prominent program aimed at reducing the energy use of large Chinese companies. Difference-in-differences analyses show that regulated firms significantly reduce their energy consumption and output but do not increase their energy efficiency. Using detailed business registration data, we link regulated firms to non-regulated firms that are part of the same conglomerate. We estimate large spillovers on cross-owned non-regulated firms, which increase both output and energy use. We then specify and calibrate a model of conglomerate production that fits our setting and the estimated effects of the regulation. The model quantifies the importance of conglomerate reallocation for aggregate outcomes, the shadow cost of the regulation, and the efficiency gains from using public information on business networks to improve the design of energy regulation.


* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 26 Jan 2021 08:34:31 -0500 2021-01-27T16:00:00-05:00 2021-01-27T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
A human-environment systems approach to prioritizing COVID-19 vaccination (January 28, 2021 11:30am) https://events.umich.edu/event/80709 80709-20777524@events.umich.edu Event Begins: Thursday, January 28, 2021 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

SEMINAR LINK: https://umich.zoom.us/s/96616169868

Madhur Anand - School of Environmental Sciences
Chris Bauch - Department of Math, Applied Math

Join us THURSDAY January 28 at 11:30 am for our first VIRTUAL SEMINAR of 2021.

Abstract:
During the COVID-19 pandemic, authorities must decide which groups to prioritize for vaccination in an evolving landscape where infection dynamics and population mitigating behavior are mutually connected in a feedback loop (i.e., human-environment interactions). Moreover, if we discover that vaccines prevent not only disease but also transmission, authorities must factor vaccine indirect protection (vaccine-generated herd immunity) into their considerations, which sometimes suggest a strategy of targeting groups that cause the most transmission. In this talk we will use a mathematical model to address the question: which age group should be prioritized for COVID-19 vaccination in order to prevent the most deaths? We developed an age-structured human-environment mathematical model for Ontario, Canada, where evolutionary game theory describes how population adherence to non-pharmaceutical interventions (NPIs) responds to case incidence. Schools and workplaces are also closed and re-opened based on reported cases. We compared strategies of vaccinating 60+ year-olds first; <20 year-olds first; uniformly by age; and a novel contact-based strategy. The last three strategies interrupt transmission while the first targets a vulnerable group. The model shows realistic dynamics whereby case notifications, NPI adherence, and lockdown undergo successive waves that interact with timing of the vaccine program to determine the relative effectiveness of the four strategies. We identify a parameter regime where transmission-interrupting strategies are more effective in preventing deaths than prioritizing older age groups. We conclude that using SARS-CoV-2 vaccines to interrupt transmission may prevent more deaths than prioritizing vulnerable age groups, depending on the time course of the pandemic in a given population.

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Livestream / Virtual Thu, 28 Jan 2021 11:30:21 -0500 2021-01-28T11:30:00-05:00 2021-01-28T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Livestream / Virtual Anand, Bauch
Statistics Department Seminar Series: Weijie Su, Assistant Professor, Wharton Statistics Department, University of Pennsylvania (January 29, 2021 10:00am) https://events.umich.edu/event/80541 80541-20738138@events.umich.edu Event Begins: Friday, January 29, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Privacy-preserving data analysis has been put on a firm mathematical foundation since the introduction of differential privacy (DP) in 2006. This privacy definition, however, has some well-known weaknesses: notably, it does not tightly handle composition. In this talk, we propose a relaxation of DP that we term "f-DP", which has a number of appealing properties and avoids some of the difficulties associated with prior relaxations. First, f-DP preserves the hypothesis testing interpretation of differential privacy, which makes its guarantees easily interpretable. It allows for lossless reasoning about composition and post-processing, and notably, a direct way to analyze privacy amplification by subsampling. We define a canonical single-parameter family of definitions within our class that is termed "Gaussian Differential Privacy", based on hypothesis testing of two shifted normal distributions. We prove that this family is focal to f-DP by introducing a central limit theorem, which shows that the privacy guarantees of any hypothesis-testing based definition of privacy (including differential privacy) converge to Gaussian differential privacy in the limit under composition. This central limit theorem also gives a tractable analysis tool. We demonstrate the use of the tools we develop by giving an improved analysis of the privacy guarantees of noisy stochastic gradient descent.

This is joint work with Jinshuo Dong and Aaron Roth.

http://www-stat.wharton.upenn.edu/~suw/

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow

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Workshop / Seminar Wed, 20 Jan 2021 14:26:36 -0500 2021-01-29T10:00:00-05:00 2021-01-29T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Weijie Su
Biophysics Seminar Series (January 29, 2021 12:00pm) https://events.umich.edu/event/81244 81244-20877916@events.umich.edu Event Begins: Friday, January 29, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

*“Ultrafast 2D IR Spectroscopy of Membrane Peptide Systems”*

Plasma membranes are the main liaisons between the intercellular and extracellular environment, playing a critical role in numerous biological processes. Recent research has challenged the long-standing “fluid mosaic model,” representing membranes as densely packed, heterogeneous environments. Within these complex membranes are transmembrane proteins which comprise up to 50% of the membrane mass, and are themselves diverse in sequence, structure, and function. Combining two-dimensional infrared spectroscopy (2D IR) and molecular dynamics simulations (MD), we have explored membrane complexity from two perspectives: first, we address the sequence heterogeneity in transmembrane peptides; and second, we explore the effect this crowded environment has on the lipids themselves and the implications this has on future membrane studies.

Site-specific 2D IR has been used to directly study localized hydration effects in a lipid membrane upon insertion of pH (Low) Insertion Peptide (pHLIP), a model membrane peptide. Semi-quantitative results indicate enhanced water penetration in the membrane core concurrent with peptide insertion, suggesting the abundance of hydrophilic residues in the pHLIP sequence drives membrane hydration. Further, crowding experiments have probed ultrafast dynamics at the lipid-water interface of model membranes as a function of transmembrane peptide concentration, revealing a non-monotonic dependence on peptide concentration linked to interfacial water structure.

Zoom link: https://umich.zoom.us/j/99088330811

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Livestream / Virtual Tue, 26 Jan 2021 10:51:35 -0500 2021-01-29T12:00:00-05:00 2021-01-29T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Jennifer Flanagan
Drosophila clock cells use multiple mechanisms to transmit time-of-day signals in the brain (January 29, 2021 12:00pm) https://events.umich.edu/event/80067 80067-20550966@events.umich.edu Event Begins: Friday, January 29, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Monica Dus

Abstract: Regulation of circadian behavior and physiology by the *Drosophila* brain clock requires communication from central clock neurons to downstream output regions, but the mechanism by which clock cells regulate downstream targets is not known. We show here that the pars intercerebralis (PI), previously identified as a target of the morning cells in the clock network, also receives input from evening cells. We determined that morning and evening clock neurons have time of day dependent connectivity to the PI, which is regulated by specific peptides as well as by fast neurotransmitters. Interestingly, PI cells that secrete the peptide DH44, and control rest:activity rhythms, are inhibited by clock inputs while insulin-producing cells (IPCs) are activated, indicating that the same clock cells can use different mechanisms to drive cycling in output neurons. Inputs of morning cells to IPCs are relevant for the circadian rhythm of feeding, reinforcing the role of the PI as a circadian relay that controls multiple behavioral outputs. Our findings provide mechanisms by which clock neurons signal to non-clock cells to drive rhythms of behavior.

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Workshop / Seminar Mon, 25 Jan 2021 19:01:07 -0500 2021-01-29T12:00:00-05:00 2021-01-29T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Annika Barber
Social, Behavioral & Experimental Economics (SBEE): Homophily, Peer Effects and Dishonesty (with Liza Charroin and Bernard Fortin) (February 3, 2021 1:00pm) https://events.umich.edu/event/80199 80199-20596097@events.umich.edu Event Begins: Wednesday, February 3, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
If individuals tend to behave like their peers, is it because of conformity, that is, the preference of people to align behavior with the behavior of their peers, homophily, that is, the tendency of people to bond with similar others, or both? We address this question in the context of ethical dilemmas. Using a peer effects model, we designed a real-effort laboratory experiment in which individuals could misreport their performance to earn more. Participants initially worked in isolation and then, depending on the condition, they were assigned peers at random or they could select their peers based on a signal on their past (dis-)honesty. This allowed us to estimate i) the effect of conformity on lying behavior, ii) the presence of homophily, and iii) whether the endogenous choice of peers generates a self-selection bias in the estimation of conformity. Our results reveal the presence of conformity on lying and homophily in the selection of peers but only among participants who were already behaving dishonestly in isolation. Participants who behaved honestly in isolation are indifferent to the information received about peers and thus, do not exhibit any preference for homophily. Conditional on the absence of a self-selection bias due to homophily, the size of peer effects is similar when peers are assigned exogenously and when they are selected by individuals.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Fri, 15 Jan 2021 09:27:46 -0500 2021-02-03T13:00:00-05:00 2021-02-03T14:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CCMB / DCMB Weekly Seminar Series (February 3, 2021 4:00pm) https://events.umich.edu/event/81571 81571-20927558@events.umich.edu Event Begins: Wednesday, February 3, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
Understanding intra-tumour heterogeneity (ITH), in particular identifying the presence of subclonal populations of cancer cells that may respond differently to treatments, is key to support precision medicine approaches. Capturing ITH from genomic measures raises however a number of computational challenges. In this talk I will present CloneSig, a method to infer ITH from "bulk" genomic data, in particular whole-exome sequencing data, and capture changes in mutational processes active in different subclones. I will then discuss the promises of single-cell genomics and some challenges it raises, in particular to transform raw count data into useful representations, integrate heterogeneous modalities, and learn gene regulation.

Short bio: Jean-Philippe Vert has been a research scientist at Google Brain in Paris and adjunct researcher at PSL University Mines ParisTech since 2018. He graduated from Ecole Polytechnique and holds a PhD in mathematics from Paris University. He was research professor and the founding director of the Centre for Computational Biology at Mines ParisTech from 2006 to 2018, team leader at the Curie Institute on computational biology of cancer (2008-2018), visiting scholar at UC Berkeley (2015-2016), and professor at the department of mathematics of Ecole normale supérieure in Paris (2016-2018).
His research interest concerns the development of statistical and machine learning methods, particularly to model complex, high-dimensional and structured data, with an application focus on computational biology, genomics and precision medicine. His recent contributions include new methods to embed structured data such as strings, graphs or permutations to vector spaces, regularization techniques to learn from limited amounts of data, and computationally efficient techniques for pattern detection and feature selection.
He is also working on several medical applications in cancer research, including quantifying and modeling cancer heterogeneity, predicting response to therapy, and modeling the genome and epigenome of cancer cells at the single-cell level.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Mon, 01 Feb 2021 14:12:04 -0500 2021-02-03T16:00:00-05:00 2021-02-03T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Jean-Philippe Vert, PhD (Research Scientist at Google Brain in Paris, Adjunct Researcher at PSL University Mines ParisTech)
Michael Beauregard Seminar in Macroeconomics (February 3, 2021 4:00pm) https://events.umich.edu/event/81270 81270-20879909@events.umich.edu Event Begins: Wednesday, February 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 26 Jan 2021 15:17:13 -0500 2021-02-03T16:00:00-05:00 2021-02-03T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Statistics Department Seminar Series: Laura Balzano, Associate Professor, Electrical Engineering and Computer Science, University of Michigan (February 5, 2021 10:00am) https://events.umich.edu/event/80542 80542-20738139@events.umich.edu Event Begins: Friday, February 5, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In order to draw inferences from large, high-dimensional datasets, we often seek simple structure that model the phenomena represented in those data. Low-rank linear structure is one of the most flexible and efficient such models, allowing efficient prediction, inference, and anomaly detection. However, classical techniques for learning low-rank models assume your data have only minor corruptions that are uniform over samples. Modern research in optimization has begun to develop new techniques to handle realistic messy data — where data are missing, have wide variations in quality, and/or are observed through nonlinear measurement systems.

In this talk we will focus on two problems. In the first, our data are heteroscedastic, ie, corrupted by one of several noise variances. This is common in problems like sensor networks or medical imaging, where different measurements of the same phenomenon are taken with different quality sensing (eg high or low radiation). In this context, learning the low-rank structure via PCA suffers from treating all data samples as if they are equally informative. We will discuss our theoretical results on weighted PCA and new algorithms for the non-convex probabilistic PCA formulation of this problem. In the second part of the talk we will extend the matrix completion problem to cases where the columns are points on low-dimensional nonlinear algebraic varieties. We discuss two optimization approaches to this problem, one kernelized algorithm and one that leverages existing LRMC techniques on a tensorized representation of the data. We also provide a formal mathematical justification for the success of our method and experimental results showing that the new approach outperforms existing state-of-the-art methods for matrix completion in many situations.

https://web.eecs.umich.edu/~girasole/?page_id=10

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow

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Workshop / Seminar Fri, 29 Jan 2021 12:53:34 -0500 2021-02-05T10:00:00-05:00 2021-02-05T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Laura Balzano
Microbiota Coordinates Diurnal Rhythms, Intestinal Innate Immunity w/ Host Circadian Clock (February 5, 2021 12:00pm) https://events.umich.edu/event/80105 80105-20558837@events.umich.edu Event Begins: Friday, February 5, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Morgan DeSantis
Abstract: Environmental light cycles entrain circadian feeding behaviors in animals that produce rhythms in exposure to foodborne bacteria. It remains unclear whether there are corresponding immunological rhythms that anticipate this microbial exposure. Here, we show that the intestinal microbiota generates diurnal rhythms in innate immunity that synchronize with host feeding rhythms. Rhythmic expression of select antimicrobial proteins was driven by daily rhythms in epithelial attachment by segmented filamentous bacteria (SFB), a member of the mouse intestinal microbiota. Rhythmic SFB attachment was driven by the circadian clock through control of host feeding rhythms. Mechanistically, rhythmic SFB attachment activated an immunological circuit involving type 3 innate lymphoid cells (ILC3). This circuit triggered oscillations in epithelial STAT3 expression that produced rhythmic antimicrobial protein expression and caused resistance to intestinal bacterial infection to vary across the day-night cycle. Thus, host feeding rhythms are synchronized with rhythms in intestinal innate immunity that anticipate exogenous microbial exposure.

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Workshop / Seminar Mon, 25 Jan 2021 18:53:39 -0500 2021-02-05T12:00:00-05:00 2021-02-05T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar John Brooks
Economics at Work (February 5, 2021 1:00pm) https://events.umich.edu/event/80969 80969-20824900@events.umich.edu Event Begins: Friday, February 5, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/qsxyePpgCqa7Vuyt7

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Workshop / Seminar Mon, 01 Feb 2021 09:50:33 -0500 2021-02-05T13:00:00-05:00 2021-02-05T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Economics@Work
HSSP 2021 Virtual Health and Wellness Conference (February 6, 2021 1:00pm) https://events.umich.edu/event/81822 81822-20961282@events.umich.edu Event Begins: Saturday, February 6, 2021 1:00pm
Location: Off Campus Location
Organized By: HSSP

The Health Sciences Scholars Program (HSSP) will be hosting the 2021 virtual Health and Wellness Conference. The conference offers sessions to help students release academic pressures and stress, study well, and incorporate wellness into your everyday life. Explore and promote the health of your mind, body, and spirit. Get expert advice from HSSP alum who have "been there" and "done that."

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Conference / Symposium Fri, 05 Feb 2021 19:49:18 -0500 2021-02-06T13:00:00-05:00 2021-02-06T17:00:00-05:00 Off Campus Location HSSP Conference / Symposium conference flyer
MIDAS Seminar Series and ICPSR Co-present: Misty Heggeness, Research Economist, US Census Bureau (February 8, 2021 4:00pm) https://events.umich.edu/event/81038 81038-20838680@events.umich.edu Event Begins: Monday, February 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

I examine the impact of the COVID-19 shock on parents’ labor supply during the initial stages of the pandemic. Using difference-in-difference estimation and monthly panel data from the Current Population Survey (CPS), I compare labor market attachment, non-work activity, hours worked, and earnings and wages of those in areas with early school closures and stay-in-place orders with those in areas with delayed or no pandemic closures. While there was no immediate impact on detachment or unemployment, mothers with jobs in early closure states were 68.8 percent more likely than mothers in late closure states to have a job but not be working as a result of early shutdowns. There was no effect on working fathers or working women without school age children. Mothers who continued working increased their work hours relative to comparable fathers; this effect, however, appears entirely driven by a reduction in fathers’ hours worked. Overall, the pandemic appears to have induced a unique immediate juggling act for working parents of school age children. Mothers took a week of leave from formal work; fathers working fulltime, for example, reduced their hours worked by 0.53 hours over the week. While experiences were different for mothers and fathers, each are vulnerable to scarring and stunted opportunities for career growth and advancement due to the pandemic.

Misty Heggeness is Principal Economist and Senior Advisor for Evaluations and Experiments at the U.S. Census Bureau. Dr. Heggeness has a PhD from the University of Minnesota. She has worked as a research economist in the U.S. federal government since 2010 and also held positions at the National Institutes of Health and the US Department of Labor. She teaches a course on policy analysis and evaluation at the University of Maryland. Her research focuses on survey response quality, poverty & inequality, gender, and the high skilled workforce and has appeared in outlets like The New York Times, Wall Street Journal, The Economist, Nature, and Science. At the Census Bureau, she leads a high-profile initiative to integrate the Census Bureau’s major frames and co-leads a 2020 administrative records census project.

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Presentation Thu, 21 Jan 2021 09:38:52 -0500 2021-02-08T16:00:00-05:00 2021-02-08T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Misty Heggeness
Community Action to Promote Healthy Environments: Research to Improve Air Quality & Health in Detroit (February 9, 2021 12:00pm) https://events.umich.edu/event/81709 81709-20943461@events.umich.edu Event Begins: Tuesday, February 9, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

With Amy Schulz (HBHE UM SPH), Stuart Batterman (EHS UM SPH), and Angela Reyes (Detroit Hispanic Development Corporation) speaking on "Community Action to Promote Healthy Environments: Research to Improve Air Quality & Health in Detroit".

ZOOM LINK: HTTPS://UMICH.ZOOM.US/J/96155698295

Organized by the Community Engagement Core & Integrated Health Sciences Core of M-LEEaD (Michigan Center on Lifestage Environmental Exposures and Disease)

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Livestream / Virtual Wed, 03 Feb 2021 16:27:30 -0500 2021-02-09T12:00:00-05:00 2021-02-09T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Livestream / Virtual Feb 9 Air Quality & Health in Detroit
Social, Behavioral & Experimental Economics (SBEE): Costly information acquisition in centralized matching markets (February 10, 2021 3:00pm) https://events.umich.edu/event/80355 80355-20705820@events.umich.edu Event Begins: Wednesday, February 10, 2021 3:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Every year during school and college admissions, students and their parents devote considerable time and effort to acquiring costly information about their own preferences. In a market where students are ranked by universities based on exam scores, we use a market design approach to explore ways to reduce wasteful information acquisition, that is, to help students avoid acquiring information about their out-of-reach schools or universities. We find that, both theoretically and experimentally, a sequential serial dictatorship mechanism leads to less wasteful information acquisition and higher student welfare than a direct serial dictatorship mechanism. This is because the sequential mechanism informs students about which universities are willing to admit them, thereby directing their search. Additionally, our experiments show that the sequential mechanism has behavioral advantages because subjects deviate from the optimal search strategy less frequently under the sequential than under the direct mechanism. We also investigate the effects of providing historical cutoff scores under the direct mechanism. We find that the provision of cutoffs can increase student welfare especially when the information costs are high, although the effect is smaller than that of a sequential mechanism.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Fri, 15 Jan 2021 09:28:32 -0500 2021-02-10T15:00:00-05:00 2021-02-10T16:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIPSE Seminar | Powering the Future: Fusion & Plasmas, the FESAC Long Range Planning Report (February 10, 2021 3:30pm) https://events.umich.edu/event/81665 81665-20941450@events.umich.edu Event Begins: Wednesday, February 10, 2021 3:30pm
Location: Off Campus Location
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

The seminar is free and open to the public.
To request the Zoom link, please send an email to:
mipse-central@umich.edu

Abstract:
A long-range plan for DOE Fusion Energy Sciences has been created to accelerate the development of fusion energy and advance plasma science. This plan is based on substantial input from the re-search community, which conveyed a wealth of creative ideas and its passion to accelerate fusion energy development and advance plasma science over an intensive two-year process. The FESAC Long Range Planning Report provides a decade-long vision for the field of fusion energy and plasma science, presenting a path to a promising future of new scientific discoveries, industrial applications, and ultimately the delivery of fusion energy.

About the Speaker:
Troy Carter is a Professor of Physics at the University of California, Los Angeles. Prof. Carter is the Director of the Basic Plasma Science Facility (BaPSF), a collaborative research facility for plasma science supported by DOE and NSF. He is also the Director of the Plasma Science at Technology Institute (PSTI) at UCLA. His research focuses on experimental studies of fundamental processes in magnetized plasmas and is motivated by current issues in magnetic confinement fusion energy research and in space and astrophysical plasmas including magnetic reconnection, turbulence and transport in magnetized plasmas, and the nonlinear physics of Alfvén waves. He was a co-recipient of the 2002 APS DPP Excellence in Plasma Physics Research Award and is a Fellow of the APS. Prof. Carter received BS degrees in Physics and Nuclear Engineering from North Carolina State University in 1995 and a PhD in Astrophysical Sciences from Princeton University in 2001.

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Lecture / Discussion Wed, 03 Feb 2021 10:23:51 -0500 2021-02-10T15:30:00-05:00 2021-02-10T16:30:00-05:00 Off Campus Location Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Troy Carter
CCMB / DCMB Weekly Seminar (February 10, 2021 4:00pm) https://events.umich.edu/event/81413 81413-20893777@events.umich.edu Event Begins: Wednesday, February 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The increasing omics data and advanced AI technology present a great opportunity for novel biomarker-driven cancer therapies. My talk will cover two parts. First, I will introduce DrBioRight, a natural language-oriented and AI-driven analytic platform for omic data analysis. This platform allows users to perform analysis directly through human languages and it improves the performance through adaptive learning. Armed with NLP and AI technologies, this analytic will maximize the utility of omics data and lead to a new paradigm for biomedical research. Second, I will discuss our recent work on enhancer RNAs. We show that the eRNAs provide explanatory power for cancer phenotypes beyond that provided by mRNA expression through resolving intratumoral heterogeneity with enhancer cell-type specificity. Our study provides a high-resolution map of eRNA loci through which enhancer activities can be quantified by RNA-seq, enabling a broad range of biomedical investigations.

Bio: Dr. Liang is a Barnhart Family Distinguished Professor in Targeted Therapies and the Deputy Chair of Department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center. He is also a professor in the Department of Systems Biology. He received his B.S. in chemistry from Peking University (China) in 2001 and Ph.D. in quantitative and computational biology from Princeton University (NJ, USA) in 2006. Dr. Liang then finished his postdoctoral training in evolutionary and computational genomics at the University of Chicago. He joined MD Anderson Cancer Center as Assistant Professor and started his own group in 2009.
At MD Anderson, Dr. Liang’s group focuses on bioinformatics tool development, integrated cancer genomic analysis, regulatory RNA regulation/modification, and cancer systems biology. His systematic studies on enhancer regulation, RNA editing, functional proteomics, sex effects, and driver mutations in cancer have generated profound impacts on the biomedical research community and attracted wide attention such as The Wall Street Journal and Newsweek. The bioinformatics tools his group developed (such as TCPA, TANRIC, FASMIC, DrBioRight) collectively have >110,000 active users worldwide. Since 2010, he has published >140 papers total citation >25,000 times), including 41 corresponding-author papers in top journals such as Cell, Cancer Cell, Nature Genetics, Nature Biotechnology, and Nature Methods.
Dr. Liang has taken leadership roles in large cancer consortium projects, including chair of The Cancer Genome Atlas (TCGA) PanCanAtlas working groups, one co-leader of International Cancer Genome Consortium (ICGC) Pan-Cancer Whole Genome Analysis Project, and one co-chair of NCI Genomic Data Commons (GDC) QC working group. He won several awards including MD Anderson R. Lee Clark Fellow Award (2014), the University of Texas System STARS Award (2015), MD Anderson Faculty Scholar Award (2018), and AACR Team Science Award (2020). He is an elected Fellow of American Association for the Advancement of Science (AAAS).

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 28 Jan 2021 11:33:05 -0500 2021-02-10T16:00:00-05:00 2021-02-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Han Liang, PhD Professor and Deputy Chair, Department of Bioinformatics and Computational Biology Professor, Department of Systems Biology Barnhart Family Distinguished Professor in Targeted Therapies The University of Texas MD Anderson Cancer Center
Michael Beauregard Seminar in Macroeconomics: Owning Up: Closely Held Firms and Wealth Inequality (February 10, 2021 4:00pm) https://events.umich.edu/event/81271 81271-20879910@events.umich.edu Event Begins: Wednesday, February 10, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

This paper studies how wealth inequality is shaped by frictions in debt and equity markets. Using micro data on households and firms for a set of Eurozone countries, I document that in countries with greater wealth inequality, there are more privately held firms and ownership of publicly traded firms is more concentrated. I develop a dynamic general equilibrium model in which entrepreneurs have the option to run a private firm and issue debt, or go public and also issue outside equity. Both forms of external finance are subject to country-specific frictions. More access to debt increases output as well as inequality. More access to outside equity also increases output, but reduces inequality. When parameters are chosen to match the facts I document on firm ownership and financing, the model predicts differences in wealth concentration across countries that closely fit the data. Quantitatively, I find that frictions in equity markets are the key driver of these differences in inequality -- they are nearly six times as important as frictions in debt markets.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 08:34:35 -0500 2021-02-10T16:00:00-05:00 2021-02-10T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Oral Health Sciences Seminar Series (February 11, 2021 12:00pm) https://events.umich.edu/event/81688 81688-20943436@events.umich.edu Event Begins: Thursday, February 11, 2021 12:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Lola Eniola-Adefeso, Ph.D.
University Diversity and Social Transformation Professor of Chemical Engineering
Vice-Chair for Graduate Studies in Chemical Engineering
Professor of Biomedical Engineering
Professor of Macromolecular Science and Engineering
Miller Faculty Scholar
Director, Cell Adhesion and Drug Delivery Lab
Associate Director, NIH Cellular Biotechnology Training Grant
University of Michigan

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Presentation Mon, 31 Jan 2022 10:25:38 -0500 2021-02-11T12:00:00-05:00 2021-02-11T13:00:00-05:00 Off Campus Location Office of Research School of Dentistry Presentation Lola Eniola-Adefeso, Ph.D.
Racial Justice in the Age of Data and AI - A Community Forum (February 11, 2021 4:00pm) https://events.umich.edu/event/81549 81549-20925393@events.umich.edu Event Begins: Thursday, February 11, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

This community forum is a follow-up event of Timnit Gebru’s recent seminar, “Computer vision: who is helped and who is harmed?” (watch video). The record-breaking attendance of the seminar and the active participation of the audience reflected the significance of this topic to our data science community. Three faculty members will moderate the forum, where attendees can share their observations and insights, and thoughts on how data scientists can be part of the solution for racial justice in the age of data and AI.

Moderators:
Dr. H. V. Jagadish, Director of the Michigan Institute for Data Science, and Professor of Computer Science and Engineering
Dr. Shobita Parthasarathy, Professor of Public Policy and Women’s Studies, Director of Science, Technology, and Public Policy Program
Dr. Sarita Schoenebeck, Associate Professor, School of Information
Dr. Apryl Williams, Assistant Professor, Communication & Media

For more information and a reading/watch list for a deeping understanding, please visit the calendar listing on the MIDAS website. (link to the right)

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Lecture / Discussion Mon, 01 Feb 2021 20:33:03 -0500 2021-02-11T16:00:00-05:00 2021-02-11T17:30:00-05:00 Off Campus Location Michigan Institute for Data Science Lecture / Discussion is AI racist?
Statistics Department Seminar Series: Alex Bouchard-Côté, Associate Professor, Department of Statistics, University of British Columbia (February 12, 2021 10:00am) https://events.umich.edu/event/80564 80564-20740177@events.umich.edu Event Begins: Friday, February 12, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In the first part of the talk, I will present an adaptive, non-reversible Parallel Tempering (PT) allowing MCMC exploration of challenging problems such as single cell phylogenetic trees. A sharp divide emerges in the behaviour and performance of reversible versus non-reversible PT schemes: the performance of the former eventually collapses as the number of parallel cores used increases whereas non-reversible benefits from arbitrarily many available parallel cores. These theoretical results are exploited to develop an adaptive scheme to efficiently optimize over annealing schedules.

In the second half, I will talk about the global communication barrier, a fundamental limit shared by both reversible and non-reversible PT methods, and on our recent work that leverage non-linear annealing paths to provably and practically break that barrier.

My group is also interested in making these advanced non-reversible Monte Carlo methods easily available to data scientists. To do so, we have designed a Bayesian modelling language to perform inference over arbitrary data types using non-reversible, highly parallel algorithms.

References:

- Non-Reversible Parallel Tempering: a Scalable Highly Parallel MCMC Scheme.
Saifuddin Syed, Alexandre Bouchard-Côté, George Deligiannidis, Arnaud Doucet.
https://arxiv.org/pdf/1905.02939.pdf
- Software: https://www.stat.ubc.ca/~bouchard/blang/

https://www.stat.ubc.ca/~bouchard/

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow

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Workshop / Seminar Fri, 05 Feb 2021 15:13:56 -0500 2021-02-12T10:00:00-05:00 2021-02-12T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Alex Bouchard-Côté
Chytrid fungi and the functional specification of actin networks (February 12, 2021 12:00pm) https://events.umich.edu/event/80068 80068-20550967@events.umich.edu Event Begins: Friday, February 12, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Hosts: Laura Buttitta & Tim James

Abstract: Eukaryotic cells often use their actin cytoskeleton for multiple functions at the same time. For example, the actin networks of human epithelial cells can *simultaneously* control cell migration, endocytosis, vesicular trafficking, cell polarity, and other actin functions important for human health. Despite having distinct functions, individual actin networks share structural components and regulators, including polymerization factors, polymer bundlers, and proteins that promote network turnover. Determining how cells control different subsets of actin functions, and how these functions change over time, are difficult questions to address given the large amount of molecular overlap and spatial proximity between functionally distinct actin networks in animal cells. Budding and fission yeasts—the other most commonly-used model systems to study actin—have spatially separated actin networks, a property that has made them powerful for determining precise molecular mechanisms underlying actin-dependent functions like endocytosis. Yeast, however, have lost important actin structures including an actin cortex and protrusions used for cell motility. Yeasts are also missing many important regulators of human actin networks, making it difficult to determine to what extent the rules of actin network specification of yeast can be applied to animal cells. To bridge this gap, my lab uses chytrid fungi as a system to study the functional specification of animal-like and yeast-like actin networks because: (a) chytrids are early-branching fungi and have retained actin regulators found in human cells that have been lost by yeast and other fungi as well as fungal-specific actin network components (1), and (b) chytrids undergo natural developmental transitions between motile, animal-like cell types with an actin cortex and sessile, yeast-like cell types with cell walls and physically separated actin networks. In this seminar, I will explain how we came to study these fascinating fungi and how we are now using chytrid fungi as a system to study the functional specification of animal-like and yeast-like actin networks and the developmental transitions between them.

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Workshop / Seminar Mon, 25 Jan 2021 19:14:40 -0500 2021-02-12T12:00:00-05:00 2021-02-12T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Lillian Fritz-Laylin
Innovations in Relating Real Life Exposures to Chemicals and Chemical Mixtures to Health Outcomes (February 12, 2021 1:00pm) https://events.umich.edu/event/79684 79684-20454248@events.umich.edu Event Begins: Friday, February 12, 2021 1:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Tentative Symposium Schedule

1:00-1:05 - Introduction
1:05-1:30 - Dr. Andreas Kortenkamp, Brunel University: “Male reproductive health – a bad cocktail of endocrine disruptors”
1:30-1:55 - Dr. Jodi Flaws, University of Illinois at Urbana-Champaign: “Applying real life phthalate mixtures from an Illinois pregnancy cohort to toxicological models”
1:55-2:20 - Dr. Laura Vandenberg, University of Massachusetts Amherst: “The mammary gland is a sensitive organ: lessons learned from fracking chemical mixtures”
2:00-2:55 - Dr. Paul Fowler, University of Aberdeen: “Exposure to the complex mixture of environmental chemicals found in human biosolids”
2:55-3:20 - Dr. Jyotsna Jagai, University of Illinois at Chicago: “Cumulative environmental quality and diabetes rates and control”
3:20-3.35 - Questions
3:35-4:00 - Panel Discussion, featuring: Dr. Jennifer McPartland, Environmental Defense Fund, Dr. Natalie Sampson, University of Michigan, Dr. Zorimar Rivera-Núñez, Rutgers University

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Workshop / Seminar Mon, 11 Jan 2021 09:15:50 -0500 2021-02-12T13:00:00-05:00 2021-02-12T16:00:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Workshop / Seminar FLYER_20210212_Symposium
"Truth, Lies, and Style: Writing and Publishing Historical Fiction" (February 16, 2021 2:00pm) https://events.umich.edu/event/80583 80583-20759736@events.umich.edu Event Begins: Tuesday, February 16, 2021 2:00pm
Location: Off Campus Location
Organized By: LSA Honors Program

For Honors creative writing alum Allison Epstein ('14), the journey between "inspiration" and "publication" was a long one—seven years long, to be exact. After drafting a novel for her senior honors thesis, Allison went on to pitch, sell, and publish that thesis as her debut novel: A Tip for the Hangman (Doubleday, Feb. 2021). Hangman is a historical thriller that follows the life of the 16th-century poet Christopher Marlowe and his secret career in service of Queen Elizabeth I's spymaster. (Her agent refers to the novel as "the Dirtbag Kit Marlowe book," a tagline Allison endorses.)

Allison will share the inspiration and historical context behind her novel, along with a behind-the-scenes look into the world of literary publishing. From the ins and outs of historical research to the white whale of signing with a literary agent, she'll explain the lesser-known aspects of how a book makes it to print. She'll also answer any questions you care to ask about Early Modern spies, a subject she delights in.


Allison Epstein is a historical fiction author based in Chicago. By day, she works as a marketing copywriter for a firm serving higher education and not-for-profit institutions. She earned her B.A. in English and creative writing from the University of Michigan in 2014 and her MFA in fiction from Northwestern University in 2020. When not writing, she enjoys good theater and terrible puns. Find her at allisonepstein.com, or on Instagram and Twitter @rapscallison.

Register on Sessions: https://myumi.ch/zxoVD

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Workshop / Seminar Mon, 11 Jan 2021 09:50:52 -0500 2021-02-16T14:00:00-05:00 2021-02-16T15:00:00-05:00 Off Campus Location LSA Honors Program Workshop / Seminar "A Tip for the Hangman" by Allison Epstein
Labor Economics: Segregation, Capital, and the Persistence of Racial Inequality (February 17, 2021 2:30pm) https://events.umich.edu/event/81195 81195-20872021@events.umich.edu Event Begins: Wednesday, February 17, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 25 Jan 2021 14:51:34 -0500 2021-02-17T14:30:00-05:00 2021-02-17T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Michael Beauregard Seminar in Macroeconomics: How do firms build market share? (with David Argente, Doireann Fitzgerald, and Anthony Priolo) (February 17, 2021 4:00pm) https://events.umich.edu/event/81274 81274-20879911@events.umich.edu Event Begins: Wednesday, February 17, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Firms are born small, grow, and die. We investigate an explanation for this process based on frictions in the accumulation of customers, across and within markets segmented by geography. We use matched retail scanner and TV advertising data on consumer food to show that entrants grow both by adding customers in new markets and by reaching new customers in continuing markets. Growth in market share within markets is not associated with changes in markups, but is associated with advertising. We use these facts to motivate and estimate a structural model of customer accumulation within and across markets. This allows us to estimate both the distribution of intrinsic heterogeneity across firms, and frictions in the accumulation of customers. We find that these frictions contribute substantially to heterogeneity in firm size, and to the gradual process of firm growth.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 15 Feb 2021 09:16:22 -0500 2021-02-17T16:00:00-05:00 2021-02-17T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Special Joint Seminar between our Department and the Genome Science Training Program (February 17, 2021 4:00pm) https://events.umich.edu/event/80415 80415-20719669@events.umich.edu Event Begins: Wednesday, February 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: The human genome sequence folds in three dimensions (3D) into a rich variety of locus-specific contact patterns. Despite growing appreciation for the importance of 3D genome folding in evolution and disease, we lack models for relating mutations in genome sequences to changes in genome structure and function. Towards that goal, we discovered that the organization of gene regulatory domains within chromosomes and the specific sequences that sit at boundaries between domains are under strong negative selection in the human population and over primate evolution. Motivated by this signature of functional importance, we developed a deep convolutional neural network, called Akita, that accurately predicts genome folding from DNA sequence alone. Representations learned by Akita underscore the importance of the structural protein CTCF but also reveal a complex grammar beyond CTCF binding sites that underlies genome folding. Akita enabled rapid in silico predictions for effects of sequence mutagenesis on the 3D genome, including differences in genome folding across species and in disease cohorts, which we are validating with CRISPR-edited genomes. This prediction-first strategy exemplifies my vision for a more proactive, rather than reactive, role for data science in biomedical research.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

Short bio: Dr. Katherine S. Pollard is Director of the Gladstone Institute of Data Science & Biotechnology, Investigator at the Chan Zuckerberg Biohub, Professor in the Department of Epidemiology & Biostatistics and Bioinformatics Graduate Program at UCSF. Her lab develops statistical models and open source bioinformatics software for the analysis of massive genomic datasets. Previously, Dr. Pollard was an assistant professor in the University of California, Davis Genome Center and Department of Statistics. She earned her PhD in Biostatistics from the University of California, Berkeley and was a comparative genomics postdoctoral fellow at the University of California, Santa Cruz. She was awarded the Thomas J. Watson Fellowship, the Sloan Research Fellowship, and the Alumna of the Year from UC Berkeley. She is a Fellow of the International Society for Computational Biology and of the California Academy of Sciences.

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Livestream / Virtual Wed, 06 Jan 2021 09:24:05 -0500 2021-02-17T16:00:00-05:00 2021-02-17T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Katherine S. Pollard, PhD (Director, Gladstone Institute of Data Science & Biotechnology; Professor, UCSF; Investigator, Chan Zuckerberg Biohub)
Powering through Uncertainty (February 18, 2021 1:00pm) https://events.umich.edu/event/80885 80885-20816994@events.umich.edu Event Begins: Thursday, February 18, 2021 1:00pm
Location: Off Campus Location
Organized By: Office of Research School of Dentistry

Platform Architect, Intel & Founder, Timouns

Dr. Simon is a biomedical engineer, author and inventor who graduated from the University of Michigan Biomedical Engineering PhD program and was a School of Dentistry T32-TEAM Training Grant trainee. Her keynote seminar titled "Powering through Uncertainty" will encourage and inspire our students, faculty and staff as we strive to meet our mission of advancing health through education, service, research and discovery.

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Livestream / Virtual Mon, 18 Jan 2021 14:05:48 -0500 2021-02-18T13:00:00-05:00 2021-02-18T14:00:00-05:00 Off Campus Location Office of Research School of Dentistry Livestream / Virtual Keynote Speaker, Arlyne Simon
Statistics Department Seminar Series: Jing Lei, Associate Professor, Department of Statistics and Data Science, Carnegie Mellon University (February 19, 2021 10:00am) https://events.umich.edu/event/80565 80565-20740178@events.umich.edu Event Begins: Friday, February 19, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: We consider the problem of testing the equality of the conditional distribution of a response variable given a set of covariates between two populations. Such a testing problem is related to transfer learning and causal inference. We develop a nonparametric procedure by combining recent advances in conformal prediction with some new ingredients such as a novel choice of conformity score and data-driven choices of weight and score functions. To our knowledge, this is the first successful attempt of using conformal prediction for testing statistical hypotheses beyond exchangeability. Our method is suitable for modern machine learning scenarios where the data has high dimensionality and large sample sizes, and can be effectively combined with existing classification algorithms to find good weight and score functions. The performance of the proposed method is demonstrated in synthetic and real data examples.

http://www.stat.cmu.edu/people/faculty/jingle/

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow

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Workshop / Seminar Mon, 08 Feb 2021 16:31:19 -0500 2021-02-19T10:00:00-05:00 2021-02-19T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Jing Lei
New roles for inter-organelle contacts in metabolism and cell fate (February 19, 2021 12:00pm) https://events.umich.edu/event/80069 80069-20550968@events.umich.edu Event Begins: Friday, February 19, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

To persist in uncertain environments, cells store excess energy as lipids in unusual organelles called lipid droplets (LDs). Ignored for decades as inert fat globules, LDs are now appreciated as specialized platforms for metabolic reactions, with key roles in cellular energetics, lipid homeostasis, stress response, signaling, and development. I will discuss how LD spatial positioning and organization within cells also influences LD function.

Secondly, I will discuss how sterol-ester lipid phase transitions within LDs can influence the
LD surface proteome, ultimately enabling LDs to adapt to specific metabolic cues.

Finally, I will discuss how inter-organelle contact sites can act as “metabolic platforms” that fine-tune metabolic pathways during nutrient stresses. I will also discuss our work examining how inter-organelle contact sites in yeast play roles in cellular decision-making
and fate.

Host: Ming Li

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Workshop / Seminar Mon, 22 Feb 2021 09:11:36 -0500 2021-02-19T12:00:00-05:00 2021-02-19T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Yellow initials MCDB and cartoon of a microscope on a blue background
Economics at Work (February 19, 2021 1:00pm) https://events.umich.edu/event/80970 80970-20824901@events.umich.edu Event Begins: Friday, February 19, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/pDtVWES5EHkqbzxC6

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Workshop / Seminar Mon, 15 Feb 2021 17:20:15 -0500 2021-02-19T13:00:00-05:00 2021-02-19T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Economics@Work Timothy Hurd
MIDAS Seminar Series, MiCHAMP, and Precision Health Co-Present: Casey Greene, School of Medicine, University of Pennsylvania (February 22, 2021 4:00pm) https://events.umich.edu/event/81040 81040-20838682@events.umich.edu Event Begins: Monday, February 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Abstract:

Biomedical research disciplines are awash in data. These data, generated by new technologies as well as old approaches, provide the opportunity to systematically extract biological patterns that were previously difficult to observe. I’ll share vignettes focusing on three areas: 1) how we can use large-scale public data to better understand data for which few observations are available; 2) some work to understand why large-scale integrative analyses are beneficial; and 3) how machine learning can help to produce more datasets suitable for integration while maintaining participant privacy.

Dr. Casey Greene is an Associate Professor of Systems Pharmacology and Translational Therapeutics in the Perelman School of Medicine at the University of Pennsylvania and the Director of the Childhood Cancer Data Lab, powered by Alex’s Lemonade Stand Foundation. His lab develops machine learning methods that integrate distinct large-scale datasets to extract the rich and intrinsic information embedded in such integrated data. This approach reveals underlying principles of genetics, cellular environments, and cellular responses to that environment. Casey’s devotion to the analysis of publicly available data doesn’t stop in the lab. In 2016, Casey established the “Research Parasite Awards” after an editorial in the New England Journal of Medicine deemed scientists who analyze other scientists’ data “research parasites.” These honors, accompanied by a cash prize, are awarded to scientists who rigorously reanalyze other people’s data to learn something new.

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Presentation Thu, 28 Jan 2021 09:51:43 -0500 2021-02-22T16:00:00-05:00 2021-02-22T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Casey Greene
Economic History: Centrality of Slavery (February 23, 2021 2:30pm) https://events.umich.edu/event/81865 81865-20982954@events.umich.edu Event Begins: Tuesday, February 23, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 14:40:20 -0500 2021-02-23T14:30:00-05:00 2021-02-23T16:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Social, Behavioral & Experimental Economics (SBEE): How Social Stratification Affects Information Processing (February 24, 2021 1:00pm) https://events.umich.edu/event/80767 80767-20785457@events.umich.edu Event Begins: Wednesday, February 24, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
The United States has long been, and continues to be, a highly segregated society. When societies separate groups of people in the ways that we do in the U.S., that separation has not only economic, political, and sociological consequences, it also affects the psychology of the people in those societies due to social cognitive processes. In this talk, I will share recent findings from my program of research that has been using the United States as a context to examine how patterns of segregation and other forms of social stratification seep into the mind and affect how people perceive and make meaning of the world around them. I will also discuss the consequences of those meaning-making processes for people’s judgments, motivations, and decisions, particularly in the domains of education, health, and environmental sustainability. I will conclude with implications of this research for social scientific theories, and the practical application of those theories.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Fri, 15 Jan 2021 09:36:39 -0500 2021-02-24T13:00:00-05:00 2021-02-24T14:15:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Labor Economics and Macroeconomics: Infrequent Wage Adjustment and Unemployment Dynamics (joint with Axel Gottfries, Pawel Krolikowski and Gary Solon) (February 24, 2021 2:30pm) https://events.umich.edu/event/81197 81197-20872024@events.umich.edu Event Begins: Wednesday, February 24, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We seek to provide a synthesis of the allocative effects of infrequent wage adjustment in long-term employment relationships subject to idiosyncratic shocks. We devise a new theory of wage dynamics that follow a “drunken walk,” whereby wages adjust minimally to satisfy participation constraints of firm and worker. The theory is amenable to analytical solution for the endogenous wage adjustment bounds, and is easily embedded into canonical models of aggregate labor market equilibrium, allowing a study of allocative implications for unemployment dynamics. A variety of extensions to accommodate an inflationary environment, on-the-job search, and costly wage cuts further allow an interpretation of recent evidence on nominal wage adjustment, base vs. non-base pay, and the possibility of inefficient separations.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 22 Feb 2021 08:44:25 -0500 2021-02-24T14:30:00-05:00 2021-02-24T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CCMB / DCMB Weekly Seminar (February 24, 2021 4:00pm) https://events.umich.edu/event/82197 82197-21052530@events.umich.edu Event Begins: Wednesday, February 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: COVID Moonshot is an international consortium aiming to discover patent-free oral antiviral against SARS-CoV-2, targeting the main protease. Operating under an open science ethos, we make all data and structures publicly available, and crowdsource molecule designs from the community. In less than a year, we went from fragment hits to nanomolar leads in biochemical and antiviral assays. In my talk, I will discuss Moonshot’s journey towards orally bioavailable, non-covalent, and non-peptidomimetic Mpro inhibitors. I will discuss how machine learning technologies have accelerated our design-make-test cycle, and the learnings we gleaned from this large-scale prospective use of algorithms.

Bio: Dr. Alpha Lee is a Group Leader in the Department of Physics, University of Cambridge. His research focuses on developing machine learning technologies that close the design-make-test cycle for small molecule drug discovery and materials discovery. He is interested in how physical and chemical insights can be integrated into the design of interpretable algorithms. Before joining Cambridge, Dr. Lee was a Fulbright Scholar at Harvard and obtained his PhD from the University of Oxford.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 17 Feb 2021 13:18:31 -0500 2021-02-24T16:00:00-05:00 2021-02-24T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Autonomous and Intelligent Cyber-Physical Systems and The Era of Big Data (February 25, 2021 1:00pm) https://events.umich.edu/event/81738 81738-20949394@events.umich.edu Event Begins: Thursday, February 25, 2021 1:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

As society enters the era of Big Data, and intelligent Cyber-Physical Systems begins to embrace it, researchers will rely more on data to train controllers or validate them from repeated simulations.

This talk will describe autonomous and intelligent Cyber-Physical Systems (CPS), and how the availability of experimental testbeds has enabled discoveries applicable for societal-scale systems - one of which is the Cognitive and Autonomous Testbed Vehicle (CAT Vehicle). It has participated in several high-profile experiments regarding heterogeneous human-driven and semi-autonomous traffic flow. Dr. Sprinkle will detail ongoing efforts that explore how collaboration with researchers in application domain fields can dramatically expand available data sets. This also provides unique opportunities for exploring the security and privacy challenges that accompany societal-scale systems.
--
About the speaker: Dr. Jonathan Sprinkle is the Litton Industries John M. Leonis Distinguished Associate Professor of Electrical and Computer Engineering at the University of Arizona and the Interim Director of the Transportation Research Institute. In 2020 he was named a Distinguished Scholar of the University of Arizona. From 2017-2019 he served as a Program Director in Cyber-Physical Systems and Smart & Connected Communities at the National Science Foundation in the CISE Directorate. In 2013 he received the NSF CAREER award, and in 2009, he received the UA's Ed and Joan Biggers Faculty Support Grant for work in autonomous systems. His work has an emphasis on industry impact, and he was recognized with the UA "Catapult Award" by Tech Launch Arizona in 2014, and in 2012 his team won the NSF I-Corps Best Team award. His research interests and experience are in model-based approaches to cyber-physical systems, and he teaches courses ranging from software modeling to mobile application development and software engineering.

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Lecture / Discussion Thu, 04 Feb 2021 10:43:23 -0500 2021-02-25T13:00:00-05:00 2021-02-25T14:00:00-05:00 Off Campus Location Center for Connected and Automated Transportation Lecture / Discussion Decorative Image
Uncovering new functions of RNA modifications in mRNA processing (February 26, 2021 12:00pm) https://events.umich.edu/event/80070 80070-20550969@events.umich.edu Event Begins: Friday, February 26, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Abstract: Emerging evidence indicates that eukaryotic messenger RNAs are extensively decorated with modified nucleosides that have the potential to regulate eukaryotic gene expression through effects on mRNA metabolism. This talk will describe the discovery that the RNA modification pseudouridine is installed co-transcriptionally to pre-mRNA at thousands of positions by multiple pseudouridine synthases, revealing an endogenous function of pre-mRNA pseudouridylation in pre-mRNA processing. This function of pseudouridine synthases is important for our understanding of the many diseases associated with human pseudouridine synthase dysregulation.


Host: JK Nandakumar

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Workshop / Seminar Sun, 21 Feb 2021 16:21:04 -0500 2021-02-26T12:00:00-05:00 2021-02-26T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Nicole Martinez
Economics at Work (February 26, 2021 1:00pm) https://events.umich.edu/event/80973 80973-20824902@events.umich.edu Event Begins: Friday, February 26, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.

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Workshop / Seminar Mon, 22 Feb 2021 15:19:48 -0500 2021-02-26T13:00:00-05:00 2021-02-26T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Economics@Work
MIDAS Seminar Series Presents: Simine Vazire, Psychology, University of Melbourne (March 1, 2021 4:00pm) https://events.umich.edu/event/81079 81079-20846537@events.umich.edu Event Begins: Monday, March 1, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

How can we tell which scientific findings are credible? Peer-reviewed journals, even prestigious ones, do not provide much assurance regarding the credibility of any individual report. Ideally, we would read each report carefully when deciding what to trust, but this is often impossible (e.g., when we lack the expertise to evaluate the methods) or impractical (e.g., when we need to evaluate research at scale). Moreover, rather than each of us making private judgments, we would all benefit from collecting and sharing evaluations from a range of experts with different areas of expertise and different blind spots and biases. The ideal would be to validate a rubric for eliciting structured quantitative ratings of quality along a wide range of dimensions, and collect and make publicly available ratings from many different and diverse experts. These scores could be combined into a variety of metrics, or “Quality Factors” (QFs), that vary in the weight placed on different qualities. These QFs would provide easily digestible and flexible quality ratings of individual scientific papers that could be useful to other scientists, to journalists and policymakers, and to the public. QFs would also help incentivize authors to “get it right” rather than just get published in prestigious journals, because rewards and recognition could be tied to these more transparent, accountable, and valid metrics rather than to journal prestige. In this talk, I discuss what this could look like for my home discipline of psychology, and describe some progress towards producing Quality Factors for psychology papers.


Simine Vazire is an associate professor in the department of psychology at the University of Melbourne. She is the director of the Personality and Self-Knowledge laboratory. She is the co-founder and current president of the Society for the Improvement of Psychological Science, a senior editor at Collabra: Psychology, and editor in chief of Social Psychological and Personality Science. Her research is funded by the National Science Foundation, and examines accuracy and bias in people’s perceptions of their own behavior and personality. She also conducts meta-science examining how people interpret scientific findings, and tracking trends in the methods and results of published studies in psychology over time. She teaches and blogs about research methods and reproducibility.

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Presentation Fri, 22 Jan 2021 10:17:46 -0500 2021-03-01T16:00:00-05:00 2021-03-01T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Simine Vazire
In Support with Communities: Early Career Equity and Environmental Health Perspectives (March 2, 2021 12:00pm) https://events.umich.edu/event/82483 82483-21108103@events.umich.edu Event Begins: Tuesday, March 2, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

This talk will take listeners through a series of environmental health research studies that have been contextualized by early career equity experiences. Projects to be discussed include work done in the United States and Nigeria. Dr. Nwanaji-Enwerem is an MD-PhD-MPP candidate in his final year at Harvard Medical School and Harvard Kennedy School and Harvard Kennedy School, and a postdoctoral research fellow in Environmental Health Sciences in the School of Public Health, UC Berkeley. He graduated Phi Beta Kappa, Valedictorian from Morehouse College with a BS in Biology, and earned his PhD in the Harvard University Biological Sciences in Public Health program. He is an NIH National Research Service Award Principal Investigator and a Paul & Daisy Soros Fellow. His present research examines the topics of environmental exposures, health biomarkers, and science/health/environmental public policy.

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Lecture / Discussion Wed, 24 Feb 2021 16:01:40 -0500 2021-03-02T12:00:00-05:00 2021-03-02T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Jamaji Nwanaji-Enwerem: Mar 2 Early Career Equity
Economic History: Understanding Persistence (March 2, 2021 2:30pm) https://events.umich.edu/event/81490 81490-20901736@events.umich.edu Event Begins: Tuesday, March 2, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 14:31:26 -0500 2021-03-02T14:30:00-05:00 2021-03-02T16:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Labor Economics: Mortality Risk Information, Survival Expectations and Sexual Behaviors (March 3, 2021 2:30pm) https://events.umich.edu/event/82519 82519-21114094@events.umich.edu Event Begins: Wednesday, March 3, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Individuals in low-income settings are often overly pessimistic about survival risk. This paper provides evidence from a randomized experiment that provided mature adults aged 45+ in Malawi with information about population mortality risks. We find a positive treatment effect on expectations about population survival and about HIV transmission risk associated with having multiple sex partners. The latter is driven by the expectations of HIV+ people living longer, making the pool of potential partners riskier. Consistent with the change in perceived HIV transmission risk, treated individuals are less likely to engage in risky sexual practices one year after the intervention.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Thu, 25 Feb 2021 10:49:30 -0500 2021-03-03T14:30:00-05:00 2021-03-03T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Michael Beauregard Seminar in Macroeconomics (March 3, 2021 4:00pm) https://events.umich.edu/event/81275 81275-20879913@events.umich.edu Event Begins: Wednesday, March 3, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 26 Jan 2021 15:46:14 -0500 2021-03-03T16:00:00-05:00 2021-03-03T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Applied Microeconomics | Industrial Organization: Algorithmic Pricing and Competition: Empirical Evidence from the German Retail Gasoline Market (March 5, 2021 10:00am) https://events.umich.edu/event/81742 81742-20949398@events.umich.edu Event Begins: Friday, March 5, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We provide the first empirical analysis of the relationship between algorithmic pricing (AP) and competition by studying the impact of adoption in Germany's retail gasoline market, where software became widely available in 2017. Because adoption dates are unknown, we identify adopting stations by testing for structural breaks in AP markers, finding most breaks to be around the time of widespread AP introduction. Because station adoption is endogenous, we instrument using headquarter adoption. Adoption increases margins, but only for non-monopoly stations. In duopoly markets, margins increase only if both stations adopt, suggesting that AP has a significant effect on competition.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Fri, 05 Feb 2021 09:44:53 -0500 2021-03-05T10:00:00-05:00 2021-03-05T11:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Statistics Department Seminar Series: Eun Yi Chung, Assistant Professor, Department of Economics, University of Illinois at Urbana-Champaign (March 5, 2021 10:00am) https://events.umich.edu/event/80566 80566-20740179@events.umich.edu Event Begins: Friday, March 5, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Classical two-sample permutation tests for equality of distributions have exact size in finite samples, but they fail to control size for testing equality of parameters that summarize each distribution. This paper proposes permutation tests for equality of parameters that are estimated at root-n or slower rates. Our general framework applies to both parametric and nonparametric models, with two samples or one sample split into two subsamples. Our tests have correct size asymptotically while preserving exact size in finite samples when distributions are equal. They have no loss in local-asymptotic power compared to tests that use asymptotic critical values. We propose confidence sets with correct coverage in large samples that also have exact coverage in finite samples if distributions are equal up to a transformation.

We apply our theory to four commonly-used hypothesis tests of non-parametric functions evaluated at a point. Lastly, simulations show good finite sample properties of our tests.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889
There will be a virtual reception to follow


https://economics.illinois.edu/profile/eunyi

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Workshop / Seminar Thu, 25 Feb 2021 11:36:34 -0500 2021-03-05T10:00:00-05:00 2021-03-05T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Eun Yi Chung
Biophysics Seminar Series (March 5, 2021 12:00pm) https://events.umich.edu/event/79991 79991-20539092@events.umich.edu Event Begins: Friday, March 5, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Virtual Seminar Series presents:

Dr. Samuel Butcher - Steenbock Professor of Biomolecular Structure, Department of Biochemistry, University of Wisconsin-Madison

*“The epitranscriptome has been shaped by the co-evolution of RNA writer and reader proteins.”*

ABSTRACT: The epitranscriptome is characterized by dozens of post-transcriptional chemical modifications to RNA.  These chemical modifications are catalyzed by enzymes, or “writers” that chemically mark both coding and non-coding RNAs.  The post-transcriptional marks are then read by protein “readers” that bind to the RNA modifications and help direct their cognate RNAs towards different pathways in the cell. I will present our work showing how RNA writers
and readers have co-evolved to shape the epitranscriptome input and output. A series of comparative molecular structures will be described that illustrate how very subtle changes in enzyme active sites of RNA modifying enzymes result in different chemical marks that have co-
evolved with RNA reader proteins, which can adopt modular quaternary structures that are specifically tuned to read different modifications. This co-evolution of RNA writers and readers impacts nearly every step of eukaryotic gene expression.

*Join us on Zoom: https://umich.zoom.us/j/92759610297*

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Livestream / Virtual Tue, 02 Mar 2021 16:25:38 -0500 2021-03-05T12:00:00-05:00 2021-03-05T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Samuel Butcher
Viral hijacking of host molecular motors to promote nuclear entry (March 5, 2021 12:00pm) https://events.umich.edu/event/82373 82373-21084381@events.umich.edu Event Begins: Friday, March 5, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

During entry, most DNA viruses must navigate the crowded cellular environment to reach the nucleus where transcription and replication of the viral genome occur. How polyomavirus (PyV), a small, DNA tumor virus, accomplishes this essential step in infection is unclear. In mammalian cells, intracellular transport is facilitated largely by two host motors, kinesin and cytoplasmic dynein, which move cargo along microtubules towards the periphery and center of the cell, respectively. We reported that dynein motor activity is required for PyV disassembly and nuclear arrival, but the exact mechanisms by which it promotes this process were unknown. Processive dynein activity requires a three-protein complex composed of the dynein motor, dynactin activator and an adaptor that confers cargo specificity. Unexpectedly, our most recent data revealed that the BICD2 adaptor is sufficient to disassemble the virus independent of the other components within the complex revealing cargo remodeling as a novel function of dynein adaptors. As BICD2 associates with both dynein and kinesin and is involved in cargo transport to the nuclear membrane, we are now investigating the role of these factors in the subsequent nuclear arrival and import of PyV.

Host: Matt Chapman

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Workshop / Seminar Sun, 21 Feb 2021 16:28:01 -0500 2021-03-05T12:00:00-05:00 2021-03-05T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Chelsey Spriggs
Economics at Work (March 5, 2021 1:00pm) https://events.umich.edu/event/80974 80974-20824904@events.umich.edu Event Begins: Friday, March 5, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/QGLeJBnhvd4UPui38

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Workshop / Seminar Mon, 01 Mar 2021 09:46:57 -0500 2021-03-05T13:00:00-05:00 2021-03-05T14:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Economics@Work
Economic Theory: Reputation Building under Obervational Learning (March 5, 2021 2:30pm) https://events.umich.edu/event/82699 82699-21161633@events.umich.edu Event Begins: Friday, March 5, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
I study a social learning model where a sequence of myopic players observe their predecessors’ actions as well as some private signals, and then forecast the behavior of a strategic long-run player. A sequence of buyers interact with a patient seller, who is either a strategic type or a commitment type that plays the optimal commitment action in every period. When each buyer observes all previous buyers’ actions and a bounded subset of the seller’s past actions, there exist equilibria in which the patient seller receives his minmax payoff since the speed of learning goes to zero as the seller becomes patient. When each buyer observes all previous buyers’ actions and an unboundedly informative private signal about the seller’s current-period action, the speed of learning is bounded away from zero and a patient seller receives at least his optimal commitment payoff in all equilibria.

To join the seminar, please contact at econ.theory-requests@umich.edu

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Workshop / Seminar Wed, 03 Mar 2021 09:53:36 -0500 2021-03-05T14:30:00-05:00 2021-03-05T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIDAS Seminar Series and Michigan AI Initiative Co-Present: Heng Ji, University of Illinois Urbana Champaign (March 8, 2021 4:00pm) https://events.umich.edu/event/81082 81082-20846538@events.umich.edu Event Begins: Monday, March 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

To combat COVID-19, clinicians and scientists all need to digest the vast amount of relevant biomedical knowledge in literature to understand the disease mechanism and the related biological functions. The first challenge is quantity. For example, nearly 2.7K new papers are published at PubMed per day. This knowledge bottleneck causes significant delay in the development of vaccines and drugs for COVID-19. The second challenge is quality due to the rise and rapid, extensive publications of preprint manuscripts without pre-publication peer review. Many research results about coronavirus from different research labs and sources are redundant, complementary or event conflicting with each other.

Let’s consider drug repurposing as a case study. Besides the long process of clinical trial and biomedical experiments, another major cause for the long process is the complexity of the problem involved and the difficulty in drug discovery in general. The current clinical trials for drug re-purposing mainly rely on symptoms by considering drugs that can treat diseases with similar symptoms. However, there are too many drug candidates and too much misinformation published from multiple sources. In addition to a ranked list of drugs, clinicians and scientists also aim to gain new insights into the underlying molecular cellular mechanisms on Covid-19, and which pre-existing conditions may affect the mortality and severity of this disease.

To tackle these two challenges, we have developed a novel and comprehensive knowledge discovery framework, COVID-KG, to accelerate scientific discovery and build a bridge between clinicians and biology scientists. COVID-KG starts by reading existing papers to build multimedia knowledge graphs (KGs), in which nodes are entities/concepts and edges represent relations involving these entities, extracted from both text and images. Given the KGs enriched with path ranking and evidence mining, COVID-KG answers natural language questions effectively. Using drug repurposing as a case study, for 11 typical questions that human experts aim to explore, we integrate our techniques to generate a comprehensive report for each candidate drug. Preliminary assessment by expert clinicians and medical school students show our generated reports are informative and sound. I will also talk about our ongoing work to extend this framework to other domains including molecular synthesis and agriculture.

Bio:

Heng Ji is a professor at Computer Science Department, and an affiliated faculty member at Electrical and Computer Engineering Department of University of Illinois at Urbana-Champaign. She is also an Amazon Scholar. She received her B.A. and M. A. in Computational Linguistics from Tsinghua University, and her M.S. and Ph.D. in Computer Science from New York University. Her research interests focus on Natural Language Processing, especially on Multimedia Multilingual Information Extraction, Knowledge Base Population and Knowledge-driven Generation. She was selected as “Young Scientist” and a member of the Global Future Council on the Future of Computing by the World Economic Forum in 2016 and 2017. The awards she received include “AI’s 10 to Watch” Award by IEEE Intelligent Systems in 2013, NSF CAREER award in 2009, Google Research Award in 2009 and 2014, IBM Watson Faculty Award in 2012 and 2014 and Bosch Research Award in 2014-2018, and ACL2020 Best Demo Paper Award. She was invited by the Secretary of the U.S. Air Force and AFRL to join Air Force Data Analytics Expert Panel to inform the Air Force Strategy 2030. She is the lead of many multi-institution projects and tasks, including the U.S. ARL projects on information fusion and knowledge networks construction, DARPA DEFT Tinker Bell team and DARPA KAIROS RESIN team. She has coordinated the NIST TAC Knowledge Base Population task since 2010. She has served as the Program Committee Co-Chair of many conferences including NAACL-HLT2018. She is elected as the North American Chapter of the Association for Computational Linguistics (NAACL) secretary 2020-2021. Her research has been widely supported by the U.S. government agencies (DARPA, ARL, IARPA, NSF, AFRL, DHS) and industry (Amazon, Google, Bosch, IBM, Disney).

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Presentation Mon, 25 Jan 2021 17:32:08 -0500 2021-03-08T16:00:00-05:00 2021-03-08T17:00:00-05:00 Off Campus Location Michigan Institute for Data Science Presentation Heng Li
Energy Equity: Health Impact Assessment of Detroit Energy's Integrated Resource Plan (March 9, 2021 12:00pm) https://events.umich.edu/event/82482 82482-21108102@events.umich.edu Event Begins: Tuesday, March 9, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Speakers include Michelle Martinez from the Michigan Environmental Justice Coalition; Carina Gronlund from the Social Environment and Health Program, Survey Research Center, UM Institute for Social Research; and Tony Reames from UM's School for Environment & Sustainability.

Webinar Series co-sponsored by Departments of Environmental Health Sciences, & Health Behavior, Health Education DEI committees.

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Lecture / Discussion Wed, 24 Feb 2021 15:55:49 -0500 2021-03-09T12:00:00-05:00 2021-03-09T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Energy Equity (Detroit) March 9 Webinar
Economic Theory (March 9, 2021 1:00pm) https://events.umich.edu/event/81712 81712-20943465@events.umich.edu Event Begins: Tuesday, March 9, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

To join the seminar, please contact at econ.theory-requests@umich.edu

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Workshop / Seminar Wed, 03 Feb 2021 17:05:34 -0500 2021-03-09T13:00:00-05:00 2021-03-09T14:20:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economic History: Voting Rights, Deindustrialization, and Republican Ascendancy in the South (March 9, 2021 2:30pm) https://events.umich.edu/event/81494 81494-20901737@events.umich.edu Event Begins: Tuesday, March 9, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 14:32:30 -0500 2021-03-09T14:30:00-05:00 2021-03-09T16:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CCMB / DCMB Weekly Seminar Series (March 10, 2021 4:00pm) https://events.umich.edu/event/82479 82479-21108092@events.umich.edu Event Begins: Wednesday, March 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Single-cell technologies have transformed biomedical research in the last few years. With single-cell sequencing, we can now simultaneously measure thousands of genomics features in a large number of cells, which provides an ultrahigh resolution phenotypic map for each individual. However, single-cell protocols are complex. Even with the most sensitive platforms, the data are often sparse and noisy. Recent development of single-cell multi-omics and spatial transcriptomics technologies further imposed additional challenges on data integration. In this talk, I will present several machine learning methods that my group recently developed for single-cell and spatial transcriptomics data analysis. I will discuss methods for simultaneous denoising, clustering and batch effect correction, single-cell multi-omics data integration, identification of spatially variable genes, generation of super-resolution gene expression, and inference of cell type distribution in spatial transcriptomics. I will illustrate our methods by showing results from ongoing collaborations on cardiometabolic disease and applications to brain and cancer data.
* * *
Biography: Dr. Li’s research interests include statistical genetics and genomics, bioinformatics, and computational biology. The central theme of her current research is to use statistical and computational approaches to understand cellular heterogeneity in human-disease-relevant tissues, to characterize gene expression diversity across cell types, to study the patterns of cell state transition and crosstalk of various cells using data generated from single-cell and spatial transcriptomics studies, and to translate these findings to the clinics. In addition to methods development, Dr. Li is also interested in collaborating with researchers seeking to identify complex disease susceptibility genes and acting cell types. She is Director of Biostatistics for the Gene Therapy Program at Penn, where she advises biostatistics and bioinformatics analysis for various gene therapy studies. She is also Chair of the Graduate Program in Biostatistics. Dr. Li actively serves in the scientific community. She served as a regular member for the NIH Genomics, Computational Biology and Technology (GCAT) study section for 6 years, and the NHGRI Center for Inherited Disease Research (CIDR) for 3 years. She is an Associate Editor of Annals of Applied Statistics, Statistics in Biosciences, PLOS Computational Biology, and Human Genetics and Genomics Advances. She is an elected member of the International Statistical Institute and a Fellow of the American Statistical Association.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 24 Feb 2021 12:57:46 -0500 2021-03-10T16:00:00-05:00 2021-03-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics: International Spillovers and Local Credit Cycle (March 10, 2021 4:00pm) https://events.umich.edu/event/81276 81276-20879915@events.umich.edu Event Begins: Wednesday, March 10, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
This paper studies the transmission of the Global Financial Cycle (GFC) to domestic credit market conditions in a large emerging market, Turkey, over 2003-13. We use administrative data covering the universe of corporate credit transactions matched to bank balance sheets
to document four facts: (1) an easing in global financial conditions leads to lower borrowing costs and an increase in local lending; (2) domestic banks more exposed to international capital markets transmit the GFC locally; (3) the fall in local currency borrowing costs is larger than foreign currency borrowing costs due to the comovement of the uncovered interest rate parity (UIP) premium with the GFC over time; (4) data on posted collateral for new loan issuances show that collateral constraints do not relax during the boom phase of the GFC.
*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Mar 2021 09:37:31 -0500 2021-03-10T16:00:00-05:00 2021-03-10T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economic Development Seminar (March 11, 2021 4:00pm) https://events.umich.edu/event/81974 81974-20998843@events.umich.edu Event Begins: Thursday, March 11, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at fspp-ipc-questions@umich.edu

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Workshop / Seminar Wed, 10 Feb 2021 15:55:00 -0500 2021-03-11T16:00:00-05:00 2021-03-11T17:20:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
International Economics and Macroeconomics (March 11, 2021 4:00pm) https://events.umich.edu/event/82403 82403-21092286@events.umich.edu Event Begins: Thursday, March 11, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

To join the seminar, please email to dbartelm@umich.edu.

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Workshop / Seminar Mon, 22 Feb 2021 16:20:28 -0500 2021-03-11T16:00:00-05:00 2021-03-11T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Labor Economics: Automation and Gender: Implications for Occupational Segregation and the Gender Skill Gap (joint with Patricia Cortes and Nicolas Guida-Johnson) (March 12, 2021 8:30am) https://events.umich.edu/event/81201 81201-20872027@events.umich.edu Event Begins: Friday, March 12, 2021 8:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract: Occupational segregation by gender, although still sizable, has decreased significantly over the last few decades. Women have also made marked gains in education relative to men, with the gender gap in college education reversing in favor of women since the early 1990s. In this paper, we examine the contribution of automation to both these phenomena. Specifically, we analyze the effects of automation on the occupational structure of men and women and overall occupational segregation as well as gender differences in skill investments. We start by documenting two facts: (1) in 1980, women were much more likely than men to be in occupations with a high risk of automation, and (2) the cross-occupational relationship between risk of automation in 1980 and the change in worker share between 1980 and 2017, though negative for both genders, is much steeper for women. Taken together, these two facts suggest that women were more likely to be displaced by automation.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Fri, 05 Mar 2021 10:44:32 -0500 2021-03-12T08:30:00-05:00 2021-03-12T09:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Applied Microeconomics | Industrial Organization: Private Monopoly and Restricted Entry – Evidence from the Notary Profession (by Frank Verboven and Biliana Yontcheva) (March 12, 2021 10:00am) https://events.umich.edu/event/81743 81743-20949399@events.umich.edu Event Begins: Friday, March 12, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Economics

ABSTRACT:

This paper studies entry and price restrictions in a private monopoly: the Latin notary system. Under this widespread system, the State appoints notaries and grants them exclusive rights to certify important economic transactions, including real estate, business registrations, and marriage and inheritance contracts. We develop an empirical framework to uncover the current policy goals behind the entry and price restrictions. We estimate a spatial demand model to infer the extent of market expansion versus business stealing from entry; a multi-output production model to infer the size of scale economies and markups; and an entry model to infer the State’s objective function (conditional on the regulated prices). We subsequently perform policy counterfactuals with welfare-maximizing and free entry. We show how policy reform would generate considerable efficiency increases, and decrease the cost of the services to consumers.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 09:03:19 -0500 2021-03-12T10:00:00-05:00 2021-03-12T11:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Statistics Department Seminar Series: Jonathan Terhorst, Assistant Professor of Statistics, University of Michigan (March 12, 2021 10:00am) https://events.umich.edu/event/80567 80567-20740180@events.umich.edu Event Begins: Friday, March 12, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In this talk, I will outline some current research challenges in statistical genetics, and describe recent progress my group has made towards solving them. First, I will introduce the sequentially Markov coalescent (SMC), which is an important class of methods for approximating the likelihood of DNA sequence data under realistic models of evolution. Examples of the types of questions we can address using SMC include: When did humans migrate out of Africa? How did polar bears fare during the last global warming event? Why did Neanderthals disappear? We derive new Bayesian and frequentist inference procedures for SMC that are faster and have less bias than existing methods. The key new insight is to establish connections between SMC and certain well-studied models in changepoint detection. In the second portion of the talk, I will discuss a new, model-based procedure we have developed for detecting signatures of natural selection in genetic data. Our estimator is adept at discovering instances of directional and balancing selection in the human genome, and has a concrete interpretation in terms of gene tree imbalance. Finally, time permitting, I will share some early results on using these and other methods to study SARS-CoV-2 biology and the ongoing global pandemic.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889 There will be a virtual reception to follow

http://www-personal.umich.edu/~jonth/

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Workshop / Seminar Fri, 05 Mar 2021 10:18:23 -0500 2021-03-12T10:00:00-05:00 2021-03-12T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Jonathan Terhorst
Biophysics Seminar Series (March 12, 2021 12:00pm) https://events.umich.edu/event/82542 82542-21116092@events.umich.edu Event Begins: Friday, March 12, 2021 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The Biophysics Seminar Series Presents:

Dr. Pratyush Tiwary - Department of Chemistry & Biochemistry and Institute for Physical Science & Technology, University of Maryland

*“Can artificial intelligence help understand and predict biomolecular dynamics?”*

ABSTRACT: The ability to rapidly learn from high-dimensional data to make reliable predictions about the future of a given system is crucial in many contexts. This could be a fly avoiding predators, or the retina processing terabytes of data almost instantaneously to guide complex human actions. In this talk we draw parallels between such tasks, and the efficient sampling of complex molecules with hundreds of thousands of atoms. Such sampling is critical for predictive computer simulations in condensed matter physics and biophysics, including but not limited to problems such as crystal nucleation, protein loop movement and drug unbinding. For this we use the Predictive Information Bottleneck (PIB) and long short-term memory (LSTM) frameworks from artificial intelligence (AI), and re-formulate them for the sampling of biomolecular structure and dynamics, especially when plagued with rare events. We demonstrate the methods on different test-pieces, where we calculate the dissociation pathway and timescales much longer than milliseconds. These include ligand dissociation from the protein lysozyme, protein kinases and and from flexible RNA. We will also discuss some generic challenges and proposed solutions regarding reliability, interpretability and extrapolative powers of AI when used in molecular simulations, drawing mutually beneficial connections between the at first glance disconnected fields of theoretical chemistry and AI.

*Join us on zoom: https://umich.zoom.us/j/92734220731*

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Livestream / Virtual Thu, 25 Feb 2021 14:10:27 -0500 2021-03-12T12:00:00-05:00 2021-03-12T13:00:00-05:00 Off Campus Location LSA Biophysics Livestream / Virtual Dr. Pratyush Tiwary
The ins and outs of bacterial organelles (March 12, 2021 12:00pm) https://events.umich.edu/event/82374 82374-21084382@events.umich.edu Event Begins: Friday, March 12, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Abstract: Open any biology textbook and you are likely to learn that, in contrast to eukaryotes, bacteria do not contain organelles to compartmentalize and facilitate cellular functions. However, numerous protein- and lipid-bounded organelles are known to exist within a diverse array of bacterial species. In my group, we aim to understand the process of compartmentalization at a molecular level in order to understand the origins and functions of bacterial organelles and exploit them for future applications. I will discuss our work on the biogenesis and subcellular organization of the magnetic magnetosome organelles of magnetotactic bacteria and our recent discovery of ferrosomes, iron-accumulating compartments that define a novel class of bacterial organelles

Host: Anthony Vecchiarelli

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Workshop / Seminar Sun, 21 Feb 2021 16:43:04 -0500 2021-03-12T12:00:00-05:00 2021-03-12T13:30:00-05:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Magnetosome chains
Economic Theory (March 12, 2021 2:30pm) https://events.umich.edu/event/81733 81733-20949387@events.umich.edu Event Begins: Friday, March 12, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

To join the seminar, please contact at econ.theory-requests@umich.edu

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Workshop / Seminar Thu, 04 Feb 2021 10:01:10 -0500 2021-03-12T14:30:00-05:00 2021-03-12T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
MIDAS Seminar Series Presents: Patricia Murrieta-Flores, Lancaster University (March 15, 2021 4:00pm) https://events.umich.edu/event/82623 82623-21147749@events.umich.edu Event Begins: Monday, March 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

The field of Digital Humanities, and particularly the increasing accessibility of digital resources, has opened a significant number of opportunities for the study of sources that can be highly relevant to history and archaeology. These opportunities include the use of methodologies from the fields of Artificial Intelligence and Computational Linguistics and the application of a diversity of techniques and methods for the large-scale analysis and exploration of collections of historical documents.

In the case of the early colonial history of Mexico, there is an enormous variety of historical documents related to the economic, social and political life at that time. An example of this is the sixteenth-century Relaciones Geográficas de Nueva España (the Geographic Reports of New Spain). Created from the responses to a questionnaire ordered by Philip II’s and obtained between 1577 and 1585, the Geographic Reports sought to compile all the information available on the American territories under Spanish rule. Due to its essential content, these reports have been the object of study by a large number of researchers, and are frequently used in the analysis of the political, social, territorial and economic situation at the time. Although numerous studies seek to understand the shifting territorial situation in New Spain, two enormous challenges have remained. The first one is the considerable size or volume of information to be analysed and compared. The second has been the precise identification of the places mentioned in these reports, especially on a large scale.

In this presentation, I will introduce the project sponsored by the Transatlantic Platform for the Humanities and Social Sciences (T-AP) called “Digging into Early Colonial Mexico: a large-scale computational analysis of historical documents”, and some of its results. Taking as a basis the historical corpus of the Geographic Reports of New Spain, the project main objectives have been: 1) to adapt and develop techniques from Artificial Intelligence, including aspects of Natural Language Processing, Text Mining and Geographic Information Systems for the extraction and analysis of historical information from this source, and 2) to design computational methodologies for the identification of possible large-scale historical patterns. This research is allowing us to clarify some of the essential geographic questions related to the period and the colonial situation in this territory. I will also present a methodology termed Geographical Text Analysis and some of the most critical outputs from this project. These include software developed to carry out this type of analysis, the first sixteenth-century digital gazetteer of Mexico and Guatemala, and the first experiments using Natural Language Processing to automatically annotate the Relaciones corpus.

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Presentation Mon, 01 Mar 2021 13:19:07 -0500 2021-03-15T16:00:00-04:00 2021-03-15T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation Patricia Murrieta-Flores
Social, Behavioral & Experimental Economics (SBEE): Wealth, Race, and Consumption Smoothing of Typical Income Shocks (March 17, 2021 1:00pm) https://events.umich.edu/event/82207 82207-21052542@events.umich.edu Event Begins: Wednesday, March 17, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We study the consumption response to typical labor income shocks and investigate how these vary by wealth and race. First, we estimate the elasticity of consumption with respect to income using an instrument based on firm-wide changes in monthly pay. While much of the consumption-smoothing literature uses variation in unusual windfall income, this instrument captures the temporary income variation that households typically experience. In addition, because it can be constructed for every worker in every month, it allows for more
precision than most previous estimates. We implement this approach in administrative bank account data and find an average elasticity of 0.23, with a standard error of 0.01. This increased precision also allows us
to address an open question about the extent of heterogeneity by wealth in the elasticity. We find a much lower consumption response for high-liquidity households, which may help discipline structural consumption
models.
Second, we use this instrument to study how wealth shapes racial inequality. An extensive body of work documents a substantial racial and ethnic wealth gap. However, less is known about how this gap translates
into differences in welfare on a month-to-month basis. We combine our instrument for typical income volatility with a new dataset linking bank account data with race and Hispanicity. We find that black (Hispanic) households cut their consumption 50 (20) percent more than white households when faced with a similarly-sized income shock. Nearly all of this differential pass-through of income to consumption is explained in a statistical sense by differences in liquid wealth. Combining our empirical estimates with a model, we show that temporary income volatility has a substantial welfare cost for all groups. Because of racial disparities in consumption smoothing, the cost is at least 50 percent higher for black households and 20 percent higher for Hispanic households than it is for white households.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Wed, 17 Feb 2021 16:31:10 -0500 2021-03-17T13:00:00-04:00 2021-03-17T14:15:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CCMB / DCMB Weekly Seminar Series featuring Sriram Chandrasekaran (Assistant Professor, Biomedical Engineering) (March 17, 2021 4:00pm) https://events.umich.edu/event/82825 82825-21179592@events.umich.edu Event Begins: Wednesday, March 17, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Drug combinations have the potential to greatly expand our pharmacopeia while reducing both cost and drug resistance. Yet the current drug-discovery approach is unable to screen the astronomical number of possible combinations in different cell types and does not account for the complex environment inside the body. We have developed AI tools - INDIGO and MAGENTA - that predict the efficacy of drug combinations based on the properties of the drugs, the pathogen, and the infection environment. We are also using modeling to identify drugs that work in synergy with the host immune system. Using INDIGO and MAGENTA, we have identified highly synergistic combinations of repurposed drugs to treat drug resistant infections including Tuberculosis, the deadliest bacterial infection. INDIGO also accurately predicts the outcome of past clinical trials of drug combinations. Our ultimate goal is to create a personalized approach to treat infections using AI.
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Biography: Chandrasekaran received his bachelor’s degree in Biotechnology from Anna University in 2008, and a PhD in Biophysics from the University of Illinois at Urbana-Champaign in 2013. He worked at Harvard University and MIT as a Harvard Junior Fellow between 2013 and 2016 and became an Assistant Professor at UM in 2017. His lab develops systems biology algorithms for drug discovery. Computer models from his lab like INDIGO and MAGENTA are being used to design effective therapies against drug resistant pathogens. His lab also develops systems biology algorithms to understand metabolic regulation. The approaches that they have created (PROM, ASTRIX, DFA, EGEM and GEMINI) perform complementary functions in modeling of metabolic and regulatory networks. Chandrasekaran’s research has been published in Cell, Genome Biology, mBio, and PNAS. For his work, Chandrasekaran previously received the 2013 Harvard Junior Fellowship, the 2011 Howard Hughes Medical Institute (HHMI) International Predoctoral Fellowship, the 2014 William Milton Fund award, 2018 UM Precision Health Investigator Award, and the 2018 Distinguished Young Investigator Award from the AICHE COBRA society.


https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 05 Mar 2021 14:44:14 -0500 2021-03-17T16:00:00-04:00 2021-03-17T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Sriram Chandrasekaran, PhD (Assistant Professor, Biomedical Engineering)
International Economics (March 18, 2021 11:30am) https://events.umich.edu/event/82404 82404-21092287@events.umich.edu Event Begins: Thursday, March 18, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

To join the seminar, please email to dbartelm@umich.edu.

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Workshop / Seminar Mon, 22 Feb 2021 16:24:34 -0500 2021-03-18T11:30:00-04:00 2021-03-18T13:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Distinguished Alumni Speaker Series: Yizao Wang, Associate Professor, Mathematical Sciences Department, University of Cincinnati (March 19, 2021 10:00am) https://events.umich.edu/event/80568 80568-20740181@events.umich.edu Event Begins: Friday, March 19, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In this talk I will go over a few recent examples of stationary sequences, of which the extremes form long-range clustering. The phenomena of clustering of extremes have been extensively investigated in the literature since 1980s. However, for most examples the extremal clustering occurs only locally. That is, the locations of extremes within each cluster are bounded and shrink to a single point at the macroscopic level after normalization. For long-range clustering, on the other hand, the locations of extremes within each cluster are unbounded, and they can be further characterized by a random closed set in the scaling limit.

There are two classes of models that recently have been shown to exhibit the phenomena of long-range clustering of extremes. One is the Karlin model, which this talk will focus on. The other is the so-called stable-regenerative model, of which if time permits I will highlight briefly some key features.

Based on joint works with Olivier Durieu (Université de Tours, France) and Gennady Samorodnitsky (Cornell University, USA).

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889 There will be a virtual reception to follow

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Workshop / Seminar Thu, 18 Mar 2021 23:22:35 -0400 2021-03-19T10:00:00-04:00 2021-03-19T11:00:00-04:00 Off Campus Location Department of Statistics Workshop / Seminar Yizao Wang
MIDAS Seminar Series and Michigan AI Initiative Co-Present: Mona Diab, Computer Science, George Washington University (March 22, 2021 4:00pm) https://events.umich.edu/event/81039 81039-20838681@events.umich.edu Event Begins: Monday, March 22, 2021 4:00pm
Location: Off Campus Location
Organized By: Michigan Institute for Data Science

Advances in machine learning have led to quite fluent natural language generation technologies. Most of our current optimizations and evaluations focus on accuracy in output. Faithful generation is considered a nice to have, a luxury. In this talk I make the argument that faithful generation is crucial to our generation technologies especially given the scale and impact NLP technologies have on people’s lives.

Mona Diab is a Full Professor of Computer Science at the George Washington University where she directs the Care4Lang NLP lab. She is also Research Scientist with Facebook AI. She conducts research in Statistical Natural Language Processing (NLP) is a rapidly growing, exciting field of research in artificial intelligence and computer science. Interdisciplinarity is inherent to NLP, drawing on the fields of computer algorithms, software engineering, statistics, machine learning, linguistics, pragmatics, information technology, etc. In NLP, researchers model language and its use, and build both analytical models and predictive ones. In Professor Diab’s NLP lab, they address problems in social media processing, building robust enabling technologies such as syntactic and semantic processing tools for written texts in different languages, information extraction tools for large data, multilingual processing, machine translation, and computational sociolinguistic processing. Professor Diab has a special interest in Arabic NLP, where the emphasis has been on investigating Arabic dialect processing where there are very few available automated resources.

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Presentation Tue, 09 Feb 2021 11:13:10 -0500 2021-03-22T16:00:00-04:00 2021-03-22T17:00:00-04:00 Off Campus Location Michigan Institute for Data Science Presentation Mona Diab
Economic History: Great Migration Book (March 23, 2021 2:30pm) https://events.umich.edu/event/81496 81496-20901739@events.umich.edu Event Begins: Tuesday, March 23, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 14:33:36 -0500 2021-03-23T14:30:00-04:00 2021-03-23T16:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Todd Barber on the Curiosity Rover (March 23, 2021 8:00pm) https://events.umich.edu/event/83025 83025-21253076@events.umich.edu Event Begins: Tuesday, March 23, 2021 8:00pm
Location: Off Campus Location
Organized By: American Institute of Aeronautics and Astronautics

Curiosity's mission to the red planet will be covered in detail by Todd Barber, a graduate of MIT and recipient of NASA's exceptional achievement award. Topics to be discussed include the history of Mars rovers at JPL, the scientific motivation for Curiosity, and the preparations for launch two days after Thanksgiving in 2011.

The science suite on board this one-ton mega rover will be presented, as well as the engineering challenges involved in getting Curiosity to the launch pad, traveling 352 million miles to Mars over 8.5 months, and ‘sticking the landing’ following the so-called ‘seven minutes of terror’ on August 5th, 2012.

Please join AIAA virtually for this event with an amazing speaker!

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Lecture / Discussion Sun, 14 Mar 2021 21:43:32 -0400 2021-03-23T20:00:00-04:00 2021-03-23T21:15:00-04:00 Off Campus Location American Institute of Aeronautics and Astronautics Lecture / Discussion Flyer
Social, Behavioral & Experimental Economics (SBEE): Bias Intolerance: Predicting Condemnation of Apologetic Perpetrators of Prejudice (March 24, 2021 1:00pm) https://events.umich.edu/event/82208 82208-21052543@events.umich.edu Event Begins: Wednesday, March 24, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
When public figures are accused of perpetrating prejudice, they often apologize. Whereas an apology may indicate to some that the perpetrator has changed and deserves forgiveness, other onlookers may continue to condemn them. What predicts condemnation, even when a perpetrator apologizes? In the present paper, we explore two factors that may jointly lead to this bias intolerance: Strong motivation to address bias coupled with beliefs that bias cannot change. Across five studies, we examined White and straight participants’ (N = 1,617) evaluations and condemnation of an apologetic ingroup perpetrator of anti-Black and anti-gay prejudice, respectively, as a function of beliefs that bias can change and motivations to address bias. Whether measured or manipulated, greater belief that bias cannot change predicted evaluating the perpetrator as currently more biased and believing they would be more biased in the future, compared to belief that bias can change. This relationship was not moderated by motivation to respond without prejudice. Believing bias cannot change did not straightforwardly predict greater condemnation. Among participants who believe bias cannot change, those who were internally motivated to respond without prejudice were particularly likely to be “bias intolerant.” We also considered additional factors that might shape evaluations and condemnation of past prejudice and found that participants’ collective guilt was related to both greater prejudice evaluations and greater condemnation. By signaling anti-prejudice norms, bias intolerance has the potential to reduce the expression of prejudice.

For information on how to watch this lecture and sign up for the SBEE mailing list to receive notice of upcoming events, please visit the SBEE website:
https://umbee.github.io/SBEE_Seminars

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Workshop / Seminar Wed, 17 Feb 2021 16:35:01 -0500 2021-03-24T13:00:00-04:00 2021-03-24T14:15:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Labor Economics: Changes in Assortative Matching: Theory and Evidence for the US (March 24, 2021 2:30pm) https://events.umich.edu/event/81203 81203-20872028@events.umich.edu Event Begins: Wednesday, March 24, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
The extent to which like-with like marry is particularly important for inequality as well as for the outcomes of children that result from the union. In this paper we discuss approaches to the measurement of changes in assortative mating. We derive two key conditions that a well-defined measure should satisfy. We argue that changes in assortativeness should be interpreted through a structural model of the marriage market; in particular, a crucial issue is how they relate to variations in the economic surplus generated by marriage. We propose a very general criterion of increase in assortativeness, and show that almost all indices used in the literature are implied by our criterion with one notable exception, that moreover violates one of our conditions. Finally, we use our approach to evaluate the evolution of assortative matching in the US over the last decades, and conclude that assortative matching has increased, particularly at the top of the education distribution.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Wed, 10 Mar 2021 11:55:49 -0500 2021-03-24T14:30:00-04:00 2021-03-24T15:50:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
CCMB / DCMB Weekly Seminar Series Featuring Duncan K. Ralph (Fred Hutchinson Cancer Research Center) (March 24, 2021 4:00pm) https://events.umich.edu/event/82733 82733-21169592@events.umich.edu Event Begins: Wednesday, March 24, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract: Antibodies are an integral part of the adaptive immune response, and are a critical component of both vaccine-induced and naturally-acquired immunity. The development of deep sequencing approaches in recent years has allowed us to sample a significant fraction of the diverse repertoire of B cell receptor sequences from which antibodies are made. These sequences encode a wealth of information on the somatic rearrangement and evolutionary processes that determine the contours of our antibody repertoires, and thus our ability to respond appropriately to pathogens and vaccines. Extracting this information, however, requires a careful inference approach across several different analysis steps. I will describe the computational approaches that we have taken to solving these problems, which constitute the partis software package, and describe their application in several projects, including HIV and Dengue data.

* * *

Biography: Duncan attended the University of California at Santa Cruz for his undergraduate studies in physics, completing his thesis on energy transport in condensed matter theory in 2005. He completed his PhD at the Massachusetts Institute of Technology in 2014, working on the Large Hadron Collider at the European particle physics laboratory (CERN). His thesis described the observation of Higgs boson decays to four leptons. Since 2014, he has worked in Frederick Matsen’s lab at the Fred Hutchinson Cancer Research Center, first as a postdoctoral researcher and more recently as a staff scientist, writing new computational methods for the analysis of B cell receptor deep sequencing data.

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Thu, 04 Mar 2021 11:20:24 -0500 2021-03-24T16:00:00-04:00 2021-03-24T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics: Consumer Bankruptcy as Aggregate Demand Management (March 24, 2021 4:00pm) https://events.umich.edu/event/81279 81279-20879919@events.umich.edu Event Begins: Wednesday, March 24, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We study the role of consumer default policy in macroeconomic stabilization. Our economy features nominal rigidities, incomplete financial markets, and heterogeneous households with access to unsecured defaultable debt. In addition to its traditional role of balancing the ex-ante cost of credit against the ex-post benefit to defaulters, the optimal bankruptcy code features an aggregate demand management objective. Consumer bankruptcy acts as an automatic stabilizer whenever the average consumption effect of default, or “ACED” (the causal effect of default on consumption, normalized by the level of debt), is larger than the marginal propensity to consume of savers. When entering a recession, the optimal policy is lenient on past debts, but promises to be harsh on future debts to encourage credit supply. We study quantitatively the extent of business cycle amplification under consumer different bankruptcy codes, and the effectiveness of bankruptcy rules that systematically respond to the business cycle.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 22 Mar 2021 09:02:32 -0400 2021-03-24T16:00:00-04:00 2021-03-24T17:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
International Economics (March 25, 2021 11:30am) https://events.umich.edu/event/82405 82405-21092288@events.umich.edu Event Begins: Thursday, March 25, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

To join the seminar, please email to dbartelm@umich.edu.

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Workshop / Seminar Mon, 22 Feb 2021 16:26:55 -0500 2021-03-25T11:30:00-04:00 2021-03-25T13:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
LHS Collaboratory March Session (March 25, 2021 12:00pm) https://events.umich.edu/event/82008 82008-21006745@events.umich.edu Event Begins: Thursday, March 25, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Speakers Stefan Boes, PhD and Sarah Mantwill, PhD from the university of Lucerne will discuss the Swiss Learning Health System.

Promoting and supporting uptake of evidence and evidence-informed decision-making in health-systems related policy and practice is a challenge. In Switzerland, the need to address this matter has been increasingly emphasized by different actors in the health system. In particular, the lack of comprehensive coordination efforts in the field of health services research, and subsequent knowledge translation activities, has been stressed. In response, the Swiss Learning Health System (SLHS) was established as a nationwide project in 2017, currently involving 10 academic partner institutions. One of the overarching objectives of the SLHS is to bridge research, policy, and practice by providing an infrastructure that supports learning cycles by: continuously identifying issues relevant to the Swiss health system, systemizing relevant evidence, presenting potential courses of action, and revising and reshaping responses. Key features of learning cycles in the SLHS include the development of policy/evidence briefs that serve as a basis for stakeholder dialogues with actors from research, policy and practice. Issues that are identified to be further pursued are monitored for potential implementation and eventually evaluated to inform new learning cycles and to support continuous learning within the system.

Dr. Boes and Dr. Mantwill will provide an overview of the SLHS and its key features, as well as its capacity building efforts to train young researchers in the field of learning health systems, and the development of a centralized metadata repository in support of creating a sufficient large evidence basis to support learning cycles in the Swiss health system. Further, they will discuss lessons learned from the past and the newest developments of the SLHS in light of a second funding phase supported by the Swiss government.

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Livestream / Virtual Thu, 25 Feb 2021 23:57:27 -0500 2021-03-25T12:00:00-04:00 2021-03-25T13:30:00-04:00 Off Campus Location Department of Learning Health Sciences Livestream / Virtual LHS Collaboratory Logo
Economic Development Seminar (March 25, 2021 4:00pm) https://events.umich.edu/event/81994 81994-21004759@events.umich.edu Event Begins: Thursday, March 25, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at fspp-ipc-questions@umich.edu

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Workshop / Seminar Thu, 11 Feb 2021 08:59:49 -0500 2021-03-25T16:00:00-04:00 2021-03-25T17:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Economic Theory: A Theory of Simplicity in Games and Mechanism Design (March 26, 2021 9:00am) https://events.umich.edu/event/81734 81734-20949388@events.umich.edu Event Begins: Friday, March 26, 2021 9:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract: We introduce a general class of simplicity standards that vary the foresight abilities required of agents in extensive-form games. Rather than planning for the entire future of a game, agents are presumed to be able to plan only for those histories they view as simple from their current perspective. Agents may update their so-called strategic plan as the game progresses, and, at any point, for the called-for action to be simply dominant, it must lead to unambiguously better outcomes, no matter what occurs at non-simple histories. We use our approach to simplicity to provide characterizations of simple mechanisms in general social choice environments both with and without trans- fers, including canonical mechanisms such as ascending auctions, posted prices, and serial dictatorship-style mechanisms. As a final application, we explain the widespread popularity of the well-known Random Priority mechanism by characterizing it as the unique mechanism that is efficient, fair, and simple to play.

To join the seminar, please contact at econ.theory-requests@umich.edu

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Workshop / Seminar Wed, 24 Mar 2021 10:18:28 -0400 2021-03-26T09:00:00-04:00 2021-03-26T10:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Applied Microeconomics | Industrial Organization: Who Benefits from Surge Pricing? (March 26, 2021 10:00am) https://events.umich.edu/event/81744 81744-20949400@events.umich.edu Event Begins: Friday, March 26, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
In the last decade, new technologies have led to a boom in real-time pricing. I analyze the most salient example, surge pricing in ride hailing. Using data from Uber, I develop an empirical model of spatial equilibrium to measure the welfare effects of surge pricing. The model is composed of demand, supply, and a matching technology. It allows for temporal and spatial heterogeneity as well as randomness in supply and demand. I find that, relative to a counterfactual with uniform pricing, surge pricing increases total welfare by 1.59% of gross revenue. Welfare effects differ substantially across sides of the market: rider surplus increases by 5.25% of gross revenue, whereas driver surplus and plat- form profits decrease by 1.81% and 1.77% of gross revenue, respectively. Riders at all income levels benefit, while disparities in driver surplus are magnified.
* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 11:41:02 -0500 2021-03-26T10:00:00-04:00 2021-03-26T11:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich
Statistics Department Seminar Series: Zachary Lipton, Assistant Professor, Departments of Machine Learning and Tepper school of Business, Carnegie Mellon University (March 26, 2021 10:00am) https://events.umich.edu/event/80569 80569-20740182@events.umich.edu Event Begins: Friday, March 26, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In this talk I will discuss distribution shift, both as an obstacle to be overcome to achieve generalization to a target distribution and as a device for establishing a guarantee that we have in fact generalized to a distribution of interest. In the first part, I will discuss the problem of label shift, where the proportion among the labels can shift but the class conditional distributions do not change, including connections to some practical problems and some theoretical results. Then I will discuss a new work in which we alter the distribution of training data in order to establish a generalization guarantee.

This seminar will be livestreamed via Zoom https://umich.zoom.us/j/94350208889. There will be a virtual reception to follow.

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Workshop / Seminar Wed, 24 Mar 2021 12:21:53 -0400 2021-03-26T10:00:00-04:00 2021-03-26T11:00:00-04:00 Off Campus Location Department of Statistics Workshop / Seminar Zachary Lipton
Economics at Work (March 26, 2021 1:00pm) https://events.umich.edu/event/82675 82675-21155689@events.umich.edu Event Begins: Friday, March 26, 2021 1:00pm
Location: Off Campus Location
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

To join the seminar, please register from the following link.
https://forms.gle/DBTkHNFtRQcexkmDA

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Workshop / Seminar Mon, 22 Mar 2021 10:21:21 -0400 2021-03-26T13:00:00-04:00 2021-03-26T14:30:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Economics@Work
TEDxUofM 2021 Conference: Ignite (March 27, 2021 3:00pm) https://events.umich.edu/event/82449 82449-21100195@events.umich.edu Event Begins: Saturday, March 27, 2021 3:00pm
Location: Off Campus Location
Organized By: TEDxUofM

SIGN UP FOR ZOOM LINK HERE: https://www.universe.com/tedxuofm2021

Ignite plays on the idea of rising from the ashes: the chance to destroy existing norms and create new ones. To us, Ignite represents our hope for a brighter future. We have the power to ignite whatever we so choose within ourselves, our loved ones, and our communities—it all starts with one idea worth spreading.

This year's conference will feature 6 amazing TEDx Talks, engaging performers, and interactive learning activities. We will be revealing our exciting lineup of speakers on tedxuofm.com and our social media links throughout February and March!

TEDxUofM: Ignite will be hosted via Zoom. Sign up for a FREE ticket through Universe! https://www.universe.com/tedxuofm2021

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Livestream / Virtual Tue, 23 Feb 2021 14:59:03 -0500 2021-03-27T15:00:00-04:00 2021-03-27T17:00:00-04:00 Off Campus Location TEDxUofM Livestream / Virtual Conference Logo
Economic History: Do You Believe in Magic? The Economic Consequences of U.S. Mobilization for the Second World War (March 30, 2021 2:30pm) https://events.umich.edu/event/81497 81497-20901740@events.umich.edu Event Begins: Tuesday, March 30, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Mon, 08 Feb 2021 14:34:44 -0500 2021-03-30T14:30:00-04:00 2021-03-30T16:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar Econ Umich