Happening @ Michigan https://events.umich.edu/list/rss RSS Feed for Happening @ Michigan Events at the University of Michigan. CANCELLED: SAVE THE DATE 11th INTERNATIONAL SYMPOSIUM (October 25, 2021 10:00am) https://events.umich.edu/event/84621 84621-21631581@events.umich.edu Event Begins: Monday, October 25, 2021 10:00am
Location:
Organized By: Center for Cell Plasticity and Organ Design

With the current state of things we have decide to cancel the Save the Date for the CPOD International Symposium.

We will update you with the new details as soon as we have a new date.

Thank you for your understanding as we work to make adjustments with the safety of all participants in mind.

Questions/Comments please contact us at: organogenesis@umich.edu

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Conference / Symposium Wed, 01 Sep 2021 10:40:09 -0400 2021-10-25T10:00:00-04:00 2021-10-25T11:00:00-04:00 Center for Cell Plasticity and Organ Design Conference / Symposium CPOD Center for Cell Plasticity and Organ Design
Social, Behavioral and Experimental Economics (SBEE) Seminar: A Lot of Diversity is Good. A Little Diversity..... On the Possibility of Collectively Accurate Classifications: A Cognitive/Computational Unpacking of Condorcet (October 25, 2021 11:30am) https://events.umich.edu/event/88314 88314-21652403@events.umich.edu Event Begins: Monday, October 25, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
In this talk, I will provide a cognitive/computational unpacking of the Condorcet Jury Theorem. The core of the talk will focus on a paper co-authored with Lu Hong, in which we construct a formal framework to study group accuracy on classification tasks. In the paper, we derive necessary and sufficient conditions for perfect accuracy and then characterize a group’s ability to make accurate classifications as a function of its diversity, size, and the accuracy of its members. For groups relying on the majority rule, we show that increasing individual accuracy produces a setwise increase in collective accuracy, but that, contrary to intuition, increases in group size do not. We further show that increasing diversity, as measured by pairwise disagreement, only guarantees increased accuracy for highly diverse groups. Finally, we derive a general condition for increasing group size to raise or lower expected accuracy assuming individuals drawn from a population. In addition to the paper, I will reframe the model using disciplinary lenses to discuss the potential for making good decision in complex environments.

(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Mon, 18 Oct 2021 11:48:45 -0400 2021-10-25T11:30:00-04:00 2021-10-25T12:45:00-04:00 Off Campus Location Department of Economics Workshop / Seminar SBEE seminar series
Public Finance: (October 25, 2021 12:00pm) https://events.umich.edu/event/87978 87978-21648128@events.umich.edu Event Begins: Monday, October 25, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Wed, 06 Oct 2021 11:11:39 -0400 2021-10-25T12:00:00-04:00 2021-10-25T13:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Alejandro Sánchez Alvarado, PhD-Variations In Biology Seminar Series (October 26, 2021 3:00pm) https://events.umich.edu/event/87459 87459-21642270@events.umich.edu Event Begins: Tuesday, October 26, 2021 3:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design alongside The Molecular, Cellular, and Developmental Biology, Ecology and Evolutionary Biology departments and the Cell and Molecular Biology CMB/Genetics Training Programs are proud to present:

Alejandro Sánchez Alvarado, PhD
Executive Director and Chief Scientific Officer
Stowers Institute

Faculty Host(s):
Carole Parent, PhD, CMB Faculty Coordinator
Trainee Host(s):
Hannah Bell, Wesley Huang, Ansley Semack, and Yi-Ju Lulu Tseng

For more information/questions email:
Laura Buttitta, PhD buttitta@umich.edu

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Workshop / Seminar Thu, 23 Sep 2021 12:44:46 -0400 2021-10-26T15:00:00-04:00 2021-10-26T16:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Workshop / Seminar Variations In Biology
Interdisciplinary Workshop on Politics and Policy (October 27, 2021 12:00pm) https://events.umich.edu/event/87822 87822-21647042@events.umich.edu Event Begins: Wednesday, October 27, 2021 12:00pm
Location: Off Campus Location
Organized By: Center for Political Studies - Institute for Social Research

Speaker: Wendy Pearlman (Northwestern University)
Join via Zoom: https://umich.zoom.us/j/91429736051

Interdisciplinary Workshops on Politics and Policy are regular seminars hosted by the Center for Political Studies. Speakers present current research on a wide range of topics. See the full schedule of talks at https://cps.isr.umich.edu/events/

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Workshop / Seminar Mon, 04 Oct 2021 10:24:50 -0400 2021-10-27T12:00:00-04:00 2021-10-27T13:00:00-04:00 Off Campus Location Center for Political Studies - Institute for Social Research Workshop / Seminar Dark blue background with text "Interdisciplinary Workshops on Politics and Policy" and Center for Political Studies logo.
Cycling Safety: From Crash Data Analysis to a Naturalistic Cycling Study (October 27, 2021 2:30pm) https://events.umich.edu/event/88208 88208-21651370@events.umich.edu Event Begins: Wednesday, October 27, 2021 2:30pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

The safety issues of cycling have become an increasing concern. This presentation, led by Drs. Shan Bao and Fred Feng, describes two unique studies related to cycling safety, from crash data analysis to a recent naturalistic cycling study in Ann Arbor, Michigan. The Crash Report Sampling System data was used in this study to identify significant factors that impact cyclists’ crash injury levels. In the naturalistic cycling study, a fleet of four electric bikes was instrumented with cameras and GPS and was given to study participants as a substitute for their own bicycle. A total of over 5,000 miles of riding data from 77 subjects were collected over two years. The dataset could be used for studying the interactions between motorists and cyclists on real-world roadways.

More about this research: https://myumi.ch/jxl0N

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About the speakers:
Dr. Bao is an Associate Professor in the Industrial and Manufacturing Systems Engineering Department, University of Michigan-Dearborn, with a joint appointment as Associate Research Scientist in the University of Michigan Transportation Research Institute’s Human Factors Group. She is also an affiliated faculty member with UM Civil and Environmental Engineering department, MIDAS and UM Robotics Institute. Dr. Bao received her Ph.D. in mechanical and industrial engineering from the University of Iowa in 2009. Her research interests focus on human factors issues related to connected and automated vehicle technologies, ADAS system evaluation, and big data analysis. She has served as the PI or co-PI of 54 research projects. She has published 72 technical publications, including 40 refereed journals articles. Shan is a member of the Human Factors and Ergonomics Society and has served as the chair of the Surface Transportation Technical Group of Human Factors and Ergonomics Society. She is a also member of the TRB Vehicle User Characteristics committee and the TRB Human Factors in Road Vehicle Automation subcommittee.

Dr. Fred Feng is an Assistant Professor in the Department of Industrial and Manufacturing Systems Engineering at the University of Michigan-Dearborn. He is also an affiliate faculty of Michigan Institute for Data Science (MIDAS). Dr. Feng's research focuses on advancing the safety of environmentally sustainable, healthy, and equitable modes of transportation, such as cycling, walking, and public transit, through the development of data-driven insights, strategies & tactics, and technologies. To this end, we use a variety of quantitative methodologies including behavioral data analysis, statistical learning, computational human performance modeling, and human factors. Dr. Feng earned his B.E. (2006) and M.S. (2009) at Tsinghua University in China, and his PhD (2015) in Industrial and Operations Engineering from the University of Michigan, Ann Arbor. Before joining UM-Dearborn, he was a postdoctoral research fellow at the University of Michigan Transportation Research Institute (UMTRI). Dr. Feng serves on the Scientific Committee of the International Cycling Safety Conference and on the Board of directors of Washtenaw Bicycling and Walking Coalition.

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Presentation Wed, 13 Oct 2021 09:51:04 -0400 2021-10-27T14:30:00-04:00 2021-10-27T15:30:00-04:00 Off Campus Location Center for Connected and Automated Transportation Presentation Decorative Image for the CCAT Research Review with Drs. Shan Bao and Fred Feng. It features the presentation title 'Cycling Safety: From Crash Data Analysis to a Naturalistic Cycling Study' and an image of a person riding in a bicycle lane.
ISR-Zwerdling Seminar in Labor Economics: Do Female Role Models Reduce the Gender Gap in Science? Evidence from French High Schools (October 27, 2021 2:30pm) https://events.umich.edu/event/87928 87928-21647709@events.umich.edu Event Begins: Wednesday, October 27, 2021 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:
We show in a large-scale field experiment that a brief exposure to female role models working in scientific fields affects high school students’ perceptions and choice of undergraduate major. While the classroom interventions generally reduce the prevalence of stereotypical views on jobs in science and gender differences in abilities, the effects on educational choices are concentrated among high-achieving girls in Grade 12. They are more likely to enroll in selective and male-dominated STEM programs in college. The most effective role model interventions are those that improved students’ perceptions of STEM careers without overemphasizing women’s underrepresentation in science.

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Workshop / Seminar Tue, 19 Oct 2021 16:34:15 -0400 2021-10-27T14:30:00-04:00 2021-10-27T16:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Department of Computational Medicine & Bioinformatics Weekly Seminar (October 27, 2021 4:00pm) https://events.umich.edu/event/88276 88276-21652019@events.umich.edu Event Begins: Wednesday, October 27, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:
Molecular classification has transformed the diagnosis and treatment of diffuse gliomas, creating targets for precision therapies. However, timely and efficient access to molecular diagnostic methods remains difficult, causing a significant barrier to deliver molecularly-targeted therapies. We aim to develop an innovative point-of-care diagnostic screening method that provides rapid and accurate molecular classification of diffuse gliomas through artificial intelligence and optical imaging in order to improve the comprehensive care of brain tumor patients.

Bio:
Dr. Todd Hollon is a neurosurgeon and research scientist who specializes in brain tumors. He is an Assistant Professor of Neurosurgery. He completed his postdoctoral training in the UM Translational Molecular Imaging Laboratory under the supervision of Drs. Daniel Orringer and Honglak Lee. His postdoctoral work focused on the application of deep neural networks to advanced imaging methods to improve the speed and accuracy of intraoperative brain tumor diagnosis. He hopes to be part of the next generation of young scientists that uses computation and machine learning to make scientific breakthroughs.

Host: Josh Welch, PhD

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

In-Person: Forum Hall, Palmer Commons

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Livestream / Virtual Thu, 14 Oct 2021 14:26:31 -0400 2021-10-27T16:00:00-04:00 2021-10-27T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual
Michael Beauregard Seminar in Macroeconomics: (October 27, 2021 4:00pm) https://events.umich.edu/event/87931 87931-21647720@events.umich.edu Event Begins: Wednesday, October 27, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract: We develop a new dataset to study asset specificity among non-financial firms. The data covers the liquidation values of all major types of assets across industries. For the determinants of asset specificity, we show that assets’ physical attributes (e.g., mobility, durability, and customization) play a crucial role; macroeconomic and industry conditions have the most impact when assets are not custom designed. We then investigate three implications of asset specificity. First, consistent with theories of investment irreversibility, high asset specificity is associated with less disinvestment, stronger investment response to uncertainty, and greater sensitivity of capital formation across countries to macroeconomic volatility. Second, the increasing prevalence of intangible assets has not significantly reduced firms’ liquidation values, but intangibles appear more scalable. Third, firms have more vertical integration in countries with weaker rule of law when asset specificity is high.

To join the seminar, please contact econ.events@umich.edu

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Workshop / Seminar Tue, 26 Oct 2021 16:34:08 -0400 2021-10-27T16:00:00-04:00 2021-10-27T17:30:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
International Economics: (October 28, 2021 11:30am) https://events.umich.edu/event/87925 87925-21647706@events.umich.edu Event Begins: Thursday, October 28, 2021 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 05 Oct 2021 16:48:45 -0400 2021-10-28T11:30:00-04:00 2021-10-28T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Econometrics: (October 28, 2021 2:30pm) https://events.umich.edu/event/87974 87974-21648124@events.umich.edu Event Begins: Thursday, October 28, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact: econometrics-seminar-requests@umich.edu

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Workshop / Seminar Wed, 06 Oct 2021 10:37:31 -0400 2021-10-28T14:30:00-04:00 2021-10-28T16:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Economic Theory: Random versus Directed Search for Scarce Resources (October 29, 2021 9:00am) https://events.umich.edu/event/88680 88680-21656601@events.umich.edu Event Begins: Friday, October 29, 2021 9:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract: This paper studies how different search protocols affect social welfare in a search market with scarcity. Agents search for objects that differ in quality either through a random or a directed search protocol. Random search protocol, in which agents are randomly paired to an object of any quality, gives rise to adversely selected markets. Directed search protocol, in which agents choose with which quality types to pair, gives rise to congestion. When utility is either non-transferable or transferable through Nash bargaining, I show that random search dominates directed search in terms of welfare, even though each agent would prefer to be able to direct her search.

To join the seminar, please contact at econ.theory-requests@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 13:40:27 -0400 2021-10-29T09:00:00-04:00 2021-10-29T10:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: Christina Knudson, Assistant Professor of Statistics, Department of Mathematics, University of St. Thomas (October 29, 2021 10:00am) https://events.umich.edu/event/84422 84422-21623924@events.umich.edu Event Begins: Friday, October 29, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Gelman and Rubin’s (Statist. Sci. 7 (1992) 457–472) convergence diagnostic is one of the most popular methods for terminating a Markov chain Monte Carlo (MCMC) sampler. Since the seminal paper, researchers have developed sophisticated methods for estimating variance of Monte Carlo averages. We show that these estimators find immediate use in the Gelman–Rubin statistic, a connection not previously established in the literature. We incorporate these estimators to upgrade both the univariate and multivariate Gelman–Rubin statistics, leading to improved stability in MCMC termination time. An immediate advantage is that our new Gelman–Rubin statistic can be calculated for a single chain. In addition, we establish a one-to-one relationship between the Gelman–Rubin statistic and effective sample size. Leveraging this relationship, we develop a principled termination criterion for the Gelman–Rubin statistic. Finally, we demonstrate the utility of our improved diagnostic via examples.


Christina Knudson is an assistant professor at the University of St. Thomas, an alumna of the University of Minnesota School of Statistics, and an organizer of the Twin Cities chapter of R Ladies. She researches likelihood-based inference for generalized linear mixed models and termination rules for Markov chain Monte Carlo. She is the creator and author of R packages glmm and stableGR.

https://cknudson.com/

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Workshop / Seminar Tue, 19 Oct 2021 13:45:06 -0400 2021-10-29T10:00:00-04:00 2021-10-29T11:00:00-04:00 Off Campus Location Department of Statistics Workshop / Seminar Christina Knudson
Division of Labor and Mechanism of Translocation in a Ring ATPase (October 29, 2021 12:00pm) https://events.umich.edu/event/84687 84687-21624427@events.umich.edu Event Begins: Friday, October 29, 2021 12:00pm
Location: Chemistry Dow Lab
Organized By: LSA Biophysics

Many transport processes in the cell are performed by a diverse but structurally and functionally related family of proteins. These proteins, which belong to the ASCE (Additional Strand, Conserved E) superfamily of ATPases, often form mutimeric rings. Despite their importance, a number of fundamental questions remain as to the coordination of the various subunits in these rings. Bacteriophage phi29 packages its 6.6 mm long double-stranded DNA using a pentameric ring nano motor Using optical tweezers, we find that this motor can work against loads of up to ~55 picoNewtons on average, making it one of the strongest molecular motors ever reported. Interestingly, the packaging rate decreases as the prohead fills, indicating that an internal pressure builds up due to DNA compression attaining the value of ~3 MegaPascals at the end of packaging, a pressure that is used as part of the mechanism of DNA injection in the next infection cycle. We have used high-resolution optical tweezers to show that the motor packages the DNA in alternating phases of dwells and bursts. During the dwell the motor exchanges nucleotide, whereas during the burst, the motor packages 10 bps of DNA per cycle. We have also characterized the steps and intersubunit coordination of this ATPase. By using non-hydrolyzable ATP analogs and stabilizers of the ADP bound to the motor, we establish where DNA binding, hydrolysis, and phosphate and ADP release occur relative to translocation during the motor’s cycle. Surprisingly, a division of labor exists among the subunits: while only 4 of the subunits translocate DNA, all 5 bind and hydrolyze ATP, suggesting that the fifth subunit fulfills a regulatory function. Furthermore, we show that the motor not only can generate force but also torque. We characterize the role played by the special subunit in this process and identify the symmetry-breaking mechanism in the motor. Finally, we use dsRNA, and RNA/DNA hybrids to establish what factor determines the size of the motor burst, which together with recent structural data, allows us to propose a novel mechanism of translocation for this motor.

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Workshop / Seminar Mon, 18 Oct 2021 09:28:00 -0400 2021-10-29T12:00:00-04:00 2021-10-29T13:00:00-04:00 Chemistry Dow Lab LSA Biophysics Workshop / Seminar Chemistry Dow Lab
MCDB Seminar > Regulation of oogenesis by nuclear receptor signaling (October 29, 2021 12:00pm) https://events.umich.edu/event/85323 85323-21626226@events.umich.edu Event Begins: Friday, October 29, 2021 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

The coupling of organism physiology and reproduction is essential for species survival. Nuclear receptors (NRs) are widely expressed transcription factors that mediate the effects of many circulating factors to modulate physiology and reproduction. My research focuses on an understudied aspect of nuclear receptor signaling in the control of oogenesis. Specifically, I am investigating how the functions of two nuclear receptors (Svp and Hr4, the homologs of COUP-TFs and GCNF) in various somatic tissues are integrated to regulate the germline stem cell (GSC) lineage in the Drosophila ovary. In contrast to many studies focused on the intrinsic roles of nuclear receptor signaling within specific cell types, my lab will investigate the circulating factors downstream of Svp and Hr4 that remotely regulate various steps of the GSC lineage. For example, my postdoctoral work revealed that global reduction of Hr4 activity in somatic cells leads to a reduction in egg laying, GSC maintenance and proliferation, egg chamber growth, and survival of early germline cysts and vitellogenic egg chambers. Interestingly, I found that Hr4 is required in distinct tissues and cell types to control different processes of oogenesis. These results suggest that NRs can have multiple parallel roles in controlling reproduction and that secreted molecules from peripheral tissues can communicate with the ovary to influence oogenesis. As an independent investigator, my lab has continued to address how communication between the ovary and various endocrine organs regulates oogenesis to ensure reproductive fitness.

Host: Laura Buttitta

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Workshop / Seminar Wed, 06 Oct 2021 17:43:00 -0400 2021-10-29T12:00:00-04:00 2021-10-29T13:00:00-04:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar microscope image of Drosophila ovary tissue
Special Physics Presentation | Journey into the World of Particle Physics and the Cosmos — and a Call for a More Just Practice of Science (October 29, 2021 12:00pm) https://events.umich.edu/event/84413 84413-21623899@events.umich.edu Event Begins: Friday, October 29, 2021 12:00pm
Location: Off Campus Location
Organized By: Department Colloquia

This presentation will live stream on the U-M Poverty Solutions Youtube: https://www.youtube.com/watch?v=Eaca6llnjhs

Chanda Prescod-Weinstein's research focuses on theoretical work at the intersection of particle physics, cosmology, and astrophysics. She is interested in scalar dark matter candidates such as axions and axion-like particles, as well as neutron stars and inflationary cosmology. She is a member of the LSST Dark Matter Group and the STROBE-X Science Working Group, where she leads Team STROBE-Ax. Before coming to the University of New Hampshire, she held a NASA Postdoctoral Program Fellowship at Goddard Space Flight Center, a Martin Luther King Postdoctoral Fellowship in Physics at MIT, and was a research associate at the University of Washington.

In her book, "The Disordered Cosmos", Dr. Chanda Prescod-Weinstein shares her love for physics, from the Standard Model of Particle Physics and what lies beyond it, to the physics of melanin in skin, to the latest theories of dark matter — all with a new spin informed by history, politics, and the wisdom of Star Trek.

One of the leading physicists of her generation, Dr. Chanda Prescod-Weinstein is also one of fewer than one hundred Black American women to earn a Ph.D. from a department of physics. Her vision of the cosmos is vibrant, buoyantly non-traditional, and grounded in Black feminist traditions.

Prescod-Weinstein urges us to recognize how science, like most fields, is rife with racism, sexism, and other dehumanizing systems. She lays out a bold new approach to science and society that begins with the belief that we all have a fundamental right to know and love the night sky. The Disordered Cosmos dreams into existence a world that allows everyone to experience and understand the wonders of the universe.

This presentation is co-sponsored by the Poverty Solutions of the U-M and the U-M Department of Physics.

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Livestream / Virtual Thu, 08 Jul 2021 15:20:30 -0400 2021-10-29T12:00:00-04:00 2021-10-29T13:00:00-04:00 Off Campus Location Department Colloquia Livestream / Virtual Dr. Chanda Prescod-Weinstein's new book!
Economics at Work (October 29, 2021 1:00pm) https://events.umich.edu/event/87789 87789-21645951@events.umich.edu Event Begins: Friday, October 29, 2021 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Tue, 26 Oct 2021 16:39:44 -0400 2021-10-29T13:00:00-04:00 2021-10-29T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar Economics at Work
Social, Behavioral & Experimental Economics (SBEE): The Common-Probability Auction Puzzle (joint with Andy Schotter) (November 1, 2021 11:30am) https://events.umich.edu/event/88151 88151-21650731@events.umich.edu Event Begins: Monday, November 1, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract: "This paper presents a puzzle in the behavior of experimental subjects in what we call common-probability auctions. In common-value auctions, uncertainty is defined over values while, in common-probability auctions, uncertainty is defined over probabilities. We find that in contrast to the substantial overbidding found in common-value auctions, bidding in strategically equivalent common-probability auctions is consistent with Nash-equilibrium. This difference between the two uncertain environments originates in subjects' strategic valuations of the object."

(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Wed, 13 Oct 2021 09:07:17 -0400 2021-11-01T11:30:00-04:00 2021-11-01T12:45:00-04:00 Off Campus Location Department of Economics Workshop / Seminar SBEE seminar series
How Can We Make a Real Difference in Healthcare? The Challenges of Implementation (November 1, 2021 4:30pm) https://events.umich.edu/event/88632 88632-21656227@events.umich.edu Event Begins: Monday, November 1, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Most of us who work in OR applications in healthcare are frustrated by the fact that planners, managers and decision makers do not seem to be suitably impressed with the mathematical beauty of our models. The literature abounds with hundreds of application papers; but when we take a closer look, few of them describe implementation. The problems in the healthcare industry are generally very similar to corresponding problems in any other sector. Hospitals have staffing issues, budget constraints, purchasing decisions, scheduling, planning, etc. The differences are subtle and often related to the culture. Over the years, I have encountered many challenges and I have been able to design approaches to deal with many of them. A few years ago, I was asked to pick the five top challenges. I can easily rattle off thirty, but selecting five was itself a challenge. In this talk, I will outline my perception of the major hurdles, provide a few examples and discuss strategies for overcoming them.

Michael Carter is a Professor in the Department of Mechanical and Industrial Engineering at the University of Toronto and Founding Director of the Centre for Healthcare Engineering (in 2009). Since 1989, his research focus has been in the area of health care resource modeling. He is on the editorial board for the journals “Health Care Management Science”, “Operations Research for Health Care”, “Health Systems” and “IISE Transactions on Healthcare Systems”. In 2012, he was inducted as a Fellow of the Canadian Academy of Engineering and in 2013, he was inducted as a Fellow of INFORMS, the international society for Operations Research and Management Science. In 2018, he became a Fellow of the Canadian Academy of Health Sciences. In 2019, he won the Northrup Frye Award for Teaching Excellence from the University of Toronto Alumni Association and in 2021, he was awarded the University of Toronto “President’s Impact Award” for his contributions to improving healthcare in Canada.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Mon, 25 Oct 2021 15:17:49 -0400 2021-11-01T16:30:00-04:00 2021-11-01T17:30:00-04:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Michael W. Carter, Ph.D., LEL, FCAE
Bayesian models for mercury effects on multiple outcomes in the Seychelles Child Development Study (November 2, 2021 12:00pm) https://events.umich.edu/event/88561 88561-21655084@events.umich.edu Event Begins: Tuesday, November 2, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Sally W. Thurston, PhD is an Associate Professor of Biostatistics and Environmental Medicine, University of Rochester, Dept of Biostatistics and Computational Biology.

ABSTRACT: The Seychelles Child Development Study (SCDS) Main Cohort was recruited to investigate the association between prenatal mercury (Hg) exposure from maternal fish consumption and the children’s subsequent development. Multiple neurodevelopmental outcomes were measured at several discrete ages. These outcomes can be grouped into different classes or "domains", such as cognition, motor, or memory. Associations of Hg and covariates may differ across outcomes and domains. Motivated by the SCDS, I will first discuss a model for multiple outcomes at a single age under the assumption that each outcome belongs to one domain and domain memberships are known. I will then briefly describe two extensions: a model in which outcomes may have partial domain membership in more than one domain, and a longitudinal multiple outcomes model for cognition when the tests of cognition change with the age of the child.

The goal of Environmental Statistics Week is to disseminate knowledge of advanced statistical methods most relevant to environmental health research with expert-led discussions on statistical concepts.

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Lecture / Discussion Fri, 22 Oct 2021 16:34:57 -0400 2021-11-02T12:00:00-04:00 2021-11-02T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion 2021 Environmental Statistics Week
How close and how much? Linking health outcomes to spatial distributions of built environment features (November 3, 2021 12:00pm) https://events.umich.edu/event/88562 88562-21655085@events.umich.edu Event Begins: Wednesday, November 3, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Veronica Berrocal, PhD, is an Associate Professor in the Department of Statistics, University of California at Irvine.

Built environment features (BEFs) refer to aspects of the human constructed environment, which may in turn support or restrict health related behaviors and thus impact health. In this talk we are interested in understanding whether the spatial distribution and quantity of fast food restaurants (FFRs) influence the risk of obesity in schoolchildren. Our analysis on the influence of patterns of FFR occurrence on obesity among Californian schoolchildren has indicated that, in 2010, among schools that are consistently assigned to a cluster, there is a lower odds of obesity amongst 9th graders who attend schools with most distant FFR occurrences in a 1-mile radius as compared to others.

The goal of Environmental Statistics Week is to disseminate knowledge of advanced statistical methods most relevant to environmental health research with expert-led discussions on statistical concepts.

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Lecture / Discussion Fri, 22 Oct 2021 16:42:53 -0400 2021-11-03T12:00:00-04:00 2021-11-03T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion 2021 Environmental Statistics Week
Rod Little - On the Definition of Response Propensity – MPSM JPSM Seminar Series (November 3, 2021 12:00pm) https://events.umich.edu/event/88318 88318-21652407@events.umich.edu Event Begins: Wednesday, November 3, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

Rod Little is Richard D. Remington Distinguished University Professor of Biostatistics at the University of Michigan, where he also holds appointments in the Department of Statistics and the Institute for Social Research. He has over 250 publications, notably on methods for the analysis of data with missing values and model-based survey inference, and the application of statistics to diverse scientific areas, including medicine, demography, economics, psychiatry, aging and the environment. Little is an elected member of the International Statistical Institute, a Fellow of the American Statistical Association and the American Academy of Arts and Sciences, and a member of the National Academy of Medicine. In 2005, Little was awarded the American Statistical Association’s Wilks Medal for research contributions, and he gave the President’s Invited Address at the Joint Statistical Meetings. He was the COPSS Fisher Lecturer at the 2012 Joint Statistics Meetings.

On the Definition of Response Propensity

Nonresponse propensities play a central role in unit nonresponse adjustments from both design and model-based perspectives, but are often not clearly defined because of lack of clarity about the variables on which the propensities are conditioned. I propose a definition of response propensity for the purpose of nonresponse adjustments, where the conditioning is restricted to include the variables measured in the survey as well as design and auxiliary variables measured for respondents and nonrespondents. The proposed definition is justified from both design-based and model-based perspectives. The role of the missing at random assumption is discussed for both perspectives, for cross-sectional surveys and longitudinal surveys with attrition.

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Lecture / Discussion Mon, 18 Oct 2021 17:53:30 -0400 2021-11-03T12:00:00-04:00 2021-11-03T13:00:00-04:00 Off Campus Location Michigan Program in Survey and Data Science Lecture / Discussion Rod Little - On the Definition of Response Propensity – MPSM JPSM Seminar Series
ISR-Zwerdling Seminar in Labor Economics: (November 3, 2021 2:30pm) https://events.umich.edu/event/88427 88427-21653873@events.umich.edu Event Begins: Wednesday, November 3, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 19 Oct 2021 16:39:28 -0400 2021-11-03T14:30:00-04:00 2021-11-03T16:00:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
MIPSE Seminar | Physics Impacts to Plasma Wave Thruster Design (November 3, 2021 3:30pm) https://events.umich.edu/event/86296 86296-21632604@events.umich.edu Event Begins: Wednesday, November 3, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The allure of electrodeless, rf based thrusters is fairly obvious in the abstract: long life due to no electrode sputtering, multi-propellant operation (in some cases), higher plasma density. Examples include capacitive, inductive, and wave-based thrusters. Generally, the fundamental application of these concepts is an rf heated plasma, expanded through a divergent magnetic nozzle. When a wave is proposed as the plasma generation mechanism, certain physical parameters are proscribed by the dispersion relation, which serves to relate plasma parameters to the thruster design. Some considerations of these impacts on plasma sources can be examined in basic models of the wave dispersion, absorption, and coupling. The conservation laws in these sources provide additional constraints. The interaction of these phenomena will be discussed from a modeling and experimental perspective for a helicon source in terms of the scaling of density with power, geometry, and coupling, with implications for wave-based thrusters.

About the Speaker:
Dr. James Gilland is a Senior Scientist at the Ohio Aerospace Institute, specializing in advanced plasma propulsion (300 W to 300 MW), including Hall thrusters (HTs), magnetoplasmadynamic thrusters, and plasma wave thrusters. He currently supports NASA Solar Electric Propulsion HT development for the NASA Gateway. Dr. Gilland has performed system and mission analyses of a range of nuclear and solar electric propulsion systems; and served as the Lead Nuclear Electric Propulsion (NEP) Engineer in NASA’s Nuclear Propulsion Office, performing analysis of multimegawatt NEP power and propulsion systems for human space exploration. He is a past NASA Innovative and Advanced Concepts Fellow for his work on propellantless propulsion using Alfven plasma waves. He served on the NASEM panel for Space Nuclear Propulsion Technologies in 2020, and on several NASA advisory panels, including the High Energy Power & Propulsion Capabilities Roadmap Team. Dr. Gilland has an MS in Aerospace Engr. from Princeton U. and a PhD in Nuclear Engr. & Engr. Physics from U. of Wisconsin.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:36:48 -0400 2021-11-03T15:30:00-04:00 2021-11-03T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Dr. James Gilland
Department of Computational Medicine & Bioinformatics Weekly Seminar (November 3, 2021 4:00pm) https://events.umich.edu/event/88449 88449-21654119@events.umich.edu Event Begins: Wednesday, November 3, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract
My research group works in the area of mathematical oncology, where we use mathematical models to decipher the complex networks of reactions inside of cancer cells and interactions between cells. Immune cells use hundreds of biochemical reactions to respond to their environment, become activated, and kill cancer cells. Understanding the complexity of these reaction networks requires computational tools and mathematical models. We combine detailed, mechanistic modeling with machine learning to study these networks, better understand cancer and immune cells, and predict ways to control tumor growth. In this talk, I will present our recent work aimed at predicting the dynamics of immune cell behaviors across three scales: intracellular signaling pathways in CAR T cells, the collective behavior of a heterogeneous population of immune cells, and tumor-immune interactions at the tissue scale. Our models generate novel mechanistic insight into immune cell activation and predict the effects of immunotherapeutic strategies.


Biography
Stacey D. Finley is the Gordon S. Marshall Early Career Chair and Associate Professor of Biomedical Engineering at the University of Southern California. Dr. Finley received her B.S. in Chemical Engineering from Florida A & M University and obtained her Ph.D. in Chemical Engineering from Northwestern University. She completed postdoctoral training at Johns Hopkins University in the Department of Biomedical Engineering. Dr. Finley joined the faculty at USC in 2013, and she leads the Computational Systems Biology Laboratory. Dr. Finley has joint appointments in the Departments of Chemical Engineering and Materials Science and Quantitative and Computational Biology, and she is a member of the USC Norris Comprehensive Cancer Center. Dr. Finley is also the Founding Director of the Center for Computational Modeling of Cancer at USC. Her research is supported by grants from NSF, NIH, and the American Cancer Society.

Selected honors. 2016 NSF Faculty Early CAREER Award; 2016 Young Innovator by the Cellular and Molecular Bioengineering journal; Leah Edelstein-Keshet Prize from the Society of Mathematical Biology; Junior Research Award from the USC Viterbi School of Engineering; the Hanna Reisler Mentorship Award; 2018 AACR NextGen Star; 2018 Orange County Engineering Council Outstanding Young Engineer; Elected Fellow of the American Institute for Medical and Biological Engineering (2021)

Hosted by: Alan Boyle, PhD

https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Wed, 20 Oct 2021 09:54:50 -0400 2021-11-03T16:00:00-04:00 2021-11-03T17:00:00-04:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Stacey D. Finley, Ph.D. (USC)
Michael Beauregard Seminar in Macroeconomics: Liquidity Traps, Prudential Policies, and International Spillovers (November 3, 2021 4:00pm) https://events.umich.edu/event/87745 87745-21645516@events.umich.edu Event Begins: Wednesday, November 3, 2021 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:
We present a simple open economy framework to study the transmission channels of monetary and macroprudential policies and evaluate the implications for international spillovers and global welfare. Using an analytical decomposition, we first identify three transmission channels: intertemporal substitution, expenditure switching, and aggregate income. Quantitatively, expenditure switching plays a prominent role for monetary policy, while macroprudential policy operates almost entirely through intertemporal substitution. Turning to the normative analysis, we show that the risk of a liquidity trap generates a monetary policy tradeoff between stabilizing output today and reducing capital flows to lower the likelihood of a future recession. However, leaning against the wind is not necessarily optimal, even in the absence of capital controls. Finally, we argue that contrary to emerging policy concerns, capital controls are not beggar-thy-neighbor and can enhance global macroeconomic stability.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Thu, 30 Sep 2021 15:15:03 -0400 2021-11-03T16:00:00-04:00 2021-11-03T17:20:00-04:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
International Economics: (November 4, 2021 11:30am) https://events.umich.edu/event/88453 88453-21654122@events.umich.edu Event Begins: Thursday, November 4, 2021 11:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Wed, 20 Oct 2021 10:11:03 -0400 2021-11-04T11:30:00-04:00 2021-11-04T13:00:00-04:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
What do we learn from the environmental surveillance of SARS-CoV-2 on and off campus? (November 4, 2021 12:00pm) https://events.umich.edu/event/88563 88563-21655086@events.umich.edu Event Begins: Thursday, November 4, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Chuanwu Xi, PhD, is a Professor of Environmental Health Sciences and Global Public Health in the School of Public Health, University of Michigan.

The goal of Environmental Statistics Week is to disseminate knowledge of advanced statistical methods most relevant to environmental health research with expert-led discussions on statistical concepts.

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Lecture / Discussion Fri, 22 Oct 2021 16:48:21 -0400 2021-11-04T12:00:00-04:00 2021-11-04T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion 2021 Environmental Statistics Week
Economic Theory: (November 5, 2021 9:00am) https://events.umich.edu/event/88903 88903-21658894@events.umich.edu Event Begins: Friday, November 5, 2021 9:00am
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 13:42:59 -0400 2021-11-05T09:00:00-04:00 2021-11-05T10:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Applied Microeconomics | Industrial Organization: Regulation and Service Provision in Dynamic Oligopoly: Evidence from Mobile Telecommunications. (November 5, 2021 10:00am) https://events.umich.edu/event/87326 87326-21641154@events.umich.edu Event Begins: Friday, November 5, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
I study coverage requirements, a common regulation in the mobile telecommunications industry that intends to accelerate the roll-out of new mobile telecommunications technologies to disadvantaged areas. I argue that the regulation may engender entry deterrence effects that limit its efficacy and lead to technology introduction patterns that are not cost-efficient. To quantify the impact of coverage requirements on market structure and the speed and cost of technology roll-out, I develop and estimate a dynamic game of entry and technology upgrade under regulation. I estimate the model using panel data on mobile technology availability at the municipality level in Brazil. In counterfactual simulations, I find that coverage requirements accelerate the introduction of 3G technology by just over 1 year, on average, and reduce firms' profits by 24% relative to a scenario with no regulation. I find the entry deterrence effects to be small. Moreover, an alternative subsidization policy leads to a similar acceleration in the roll-out of 3G and substantially higher aggregate profits, likely increasing aggregate welfare relative to coverage requirements.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 21 Sep 2021 12:11:59 -0400 2021-11-05T10:00:00-04:00 2021-11-05T11:20:00-04:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: Ning Ning, Postdoctoral Research Fellow, Department of Statistics, University of Michigan. (November 5, 2021 10:00am) https://events.umich.edu/event/88820 88820-21658554@events.umich.edu Event Begins: Friday, November 5, 2021 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Disease transmission systems are highly nonlinear and stochastic and are imperfectly observable. However, conducting high-dimensional parameter learning for partially observed, nonlinear, and stochastic spatiotemporal processes is a methodological challenge and is an open problem so far. We propose the iterated block particle filter (IBPF) algorithm for learning high-dimensional parameters over graphical state space models with general state spaces, measures, transition densities, and graph structure. Theoretical performance guarantees are obtained on beating the curse of dimensionality (COD), algorithm convergence, and likelihood maximization. Experiments on a highly nonlinear and non-Gaussian spatiotemporal model for measles transmission reveal that the iterated ensemble Kalman filter algorithm (Li et al. (2020), Science) is ineffective and the iterated filtering algorithm (Ionides et al. (2015), PNAS) suffers from the COD, while our IBPF algorithm beats COD consistently across various experiments with different metrics.

Talk based on paper: "Iterated Block Particle Filter for High-dimensional Parameter Learning: Beating the Curse of Dimensionality'', Ning Ning and Edward Ionides, ArXiv: https://arxiv.org/abs/2110.10745, 2021.

Ning Ning is currently a Postdoctoral Research Fellow in the Dept. of Statistics at the University of Michigan, Ann Arbor. Her research interests are stochastic processes, Markov chains, time series, networks, and machine learning. She received her PhD in Statistics and Applied Probability at UCSB. Prior to joining University of Michigan, she was holding a position as Postdoctoral Research Associate in the Dept. of Applied Math at the Univ. of Washington, Seattle. Her personal website is https://sites.google.com/site/patricianing/

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Workshop / Seminar Mon, 01 Nov 2021 12:29:22 -0400 2021-11-05T10:00:00-04:00 2021-11-05T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Ning Ning
How much evidence do you need? Data Science to Inform Environmental Policy During the COVID-19 Pandemic (November 5, 2021 12:00pm) https://events.umich.edu/event/88564 88564-21655087@events.umich.edu Event Begins: Friday, November 5, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Francesca Dominici, PhD, is Professor of Biostatistics at the Harvard T.H. Chan School of Public Health and Co-Director of the Data Science Initiative at Harvard University.

The goal of Environmental Statistics Week is to disseminate knowledge of advanced statistical methods most relevant to environmental health research with expert-led discussions on statistical concepts.

Registration required. https://umich.zoom.us/s/96276431694

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Lecture / Discussion Thu, 04 Nov 2021 13:50:04 -0400 2021-11-05T12:00:00-04:00 2021-11-05T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion 2021 Environmental Statistics Week
MCDB Seminar > Structure, biogenesis, and engineering of the pyrenoid (November 5, 2021 12:00pm) https://events.umich.edu/event/85324 85324-21626227@events.umich.edu Event Begins: Friday, November 5, 2021 12:00pm
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Anthony Vecchiarelli

This seminar will now be virtual.
Zoom link/password available in the MCDB Weekly update or
email: mcdb.seminar.info@umich.edu

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Workshop / Seminar Fri, 29 Oct 2021 10:29:41 -0400 2021-11-05T12:00:00-04:00 2021-11-05T13:00:00-04:00 Off Campus Location Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Yellow MCDB initials and cartoon of microscope on blue
RNA Diffusion Behavior Changes Under Hyperosmotic Phase Separation & Coupled Oscillators in Developmental Patterning and Growth (November 5, 2021 12:00pm) https://events.umich.edu/event/84770 84770-21624926@events.umich.edu Event Begins: Friday, November 5, 2021 12:00pm
Location: Chemistry Dow Lab
Organized By: LSA Biophysics

Proteins and RNAs can form functional biological condensates, also known as me braneless organelles, via liquid-liquid phase separation (LLPS). The partitioning of different proteins and RNAs between the dilute phase and the condensed phase provides delicate regulation over their functions, from promoting biochemical reactions and specific intermolecular interactions, to sequestering key molecules from downstream processing or signaling. Hyperosmotic phase separation (HOPS) is a recently discovered LLPS triggered by the hyperosmotic compression of cell volume. A majority of homo-multimeric proteins are shown to undergo HOPS in several cell types, including kidney cells that experience osmolarity fluctuations daily. Moreover, HOPS is much faster than most cellular LLPS processes (within ~10 s versus over minutes to hours), and thus HOPS condensates could be first responders sensing cell volume change and priming other stress responses. However, it was unclear whether RNAs contribute to HOPS and how HOPS impacts the diffusion behaviors and functions of different RNAs. Here, I used both fixed-cell super-resolution imaging and live-cell single molecule RNA tracking to quantify the interaction of mRNAs, lncRNAs, and miRNAs with HOPS condensates, and measure the change in their diffusion behaviors in the presence of HOPS. The preliminary results suggest that different RNAs have distinctive partitioning behaviors among HOPS condensates, and long-range active transport of RNAs are diminished under hyperosmotic conditions, presumably due to the compartmentalization by HOPS condensates.
&
Coordinated regulation of cell proliferation and differentiation is fundamental to the growth and patterning of multicellular structures. To understand how growth and patterning are coupled during vertebrate development, we designed both in-vivo and in-vitro systems to study the interactions between the cell cycle and the segmentation clock across different scales. We use a 3D zebrafish embryonic tissue model to demonstrate that the phase dynamics of the cell cycle and segmentation clock are spatially dependent. To further study the spatiotemporal dynamics of the two clocks, we designed a microfluidic oscillator device to show that fine tuning kinetic parameters allows control of morphogen gradients, laying preliminary work towards constructing an artificial segmentation clock

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Workshop / Seminar Mon, 01 Nov 2021 13:44:12 -0400 2021-11-05T12:00:00-04:00 2021-11-05T13:00:00-04:00 Chemistry Dow Lab LSA Biophysics Workshop / Seminar Chemistry Dow Lab
Economics at Work (November 5, 2021 1:00pm) https://events.umich.edu/event/87790 87790-21645952@events.umich.edu Event Begins: Friday, November 5, 2021 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Fri, 01 Oct 2021 16:35:45 -0400 2021-11-05T13:00:00-04:00 2021-11-05T14:30:00-04:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Social, Behavioral and Experimental Economics (SBEE) Seminar: On Fooling Yourself: The Mechanics of Motivated Reasoning (November 8, 2021 11:30am) https://events.umich.edu/event/85648 85648-21627920@events.umich.edu Event Begins: Monday, November 8, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

ABSTRACT: People have a remarkable talent for reaching conclusions about themselves, the world, and their place in it that flatter themselves. The tendency has many names: rationalization, wishful thinking, self-deception, defensive processing—but the main overarching term is motivated reasoning. In this talk, I discuss psychological perspectives on motivated reasoning. I touch on the variety of motivations that underlie people’s judgments (or whether any motivation does at all), the reach of motivated reasoning, and finally potential psychological mechanics that support it.

(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Tue, 14 Sep 2021 16:15:31 -0400 2021-11-08T11:30:00-05:00 2021-11-08T12:45:00-05:00 Off Campus Location Department of Economics Workshop / Seminar SBEE seminar series
Cognitive Science Seminar Series: Inner Speech and Conscious Reasoning (November 8, 2021 2:30pm) https://events.umich.edu/event/88796 88796-21657770@events.umich.edu Event Begins: Monday, November 8, 2021 2:30pm
Location: Off Campus Location
Organized By: Weinberg Institute for Cognitive Science

The Cognitive Science Seminar Series welcomes guest presenter Wade Munroe, postdoctoral research fellow, Weinberg Institute for Cognitive Science. Wade will present "Thinking Through Talking to Yourself: Inner Speech as a Vehicle of Conscious Reasoning."

ABSTRACT
Our conscious thought, at least at times, seems suffused with language. We may experience deliberation as if we were ‘talking in our head’, thus using inner speech to verbalize our premises, lemmas, and conclusions without employing our vocal tract to generate explicit utterances. The claim that we can consciously reason through inner speech—that is, that inner speech can serve as the representational vehicle for conscious reasoning—is, prima facie, intuitively compelling. Even those who are dubious of the claim offer explanations for why it may erroneously appear as if inner speech ‘utterances’ can constitute occurrent propositional attitudes, like occurrent judgements, suppositions, etc. (cf. Carruthers 2011). However, intuitions notwithstanding, the claim that we can consciously reason through inner speech takes considerable work to defend.

Peter Langland-Hassan (2014) has forcefully argued that, insofar as inner speech possesses a sensory, vocal character, it cannot carry the sort of propositional contents required to function as, say, an occurrent judgment in conscious deliberation. In this talk, I argue that, pace Langland-Hassan, an inner speech utterance can be the bearer of propositional contents such that it can function as an occurrent judgment. As I demonstrate, the functional role a mental state plays in working memory is determined in a flexible and context sensitive manner by metacognitive monitoring and control procedures. An inner speech utterance functions as an occurrent judgment (and can, thus, function as a premise, lemma, or conclusion in a line of conscious reasoning) when it is experienced with a level of certainty that exceeds one’s threshold of confidence for acceptance. In virtue of an agent experiencing an inner speech utterance with a sufficient level of certainty, the utterance plays the functional role of an occurrent judgment through, e.g., terminating inquiry and causing overt actions (like overtly asserting the words rehearsed in inner speech) and further mental states (like further inner speech utterances).

All cognitive science seminars this semester are virtual. For Zoom passcode information, or to be added to the seminar distribution list, please email cogsci-seminar-requests@umich.edu.

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Lecture / Discussion Fri, 05 Nov 2021 09:09:22 -0400 2021-11-08T14:30:00-05:00 2021-11-08T15:50:00-05:00 Off Campus Location Weinberg Institute for Cognitive Science Lecture / Discussion
Public Finance: (November 8, 2021 4:00pm) https://events.umich.edu/event/88900 88900-21658886@events.umich.edu Event Begins: Monday, November 8, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 12:11:24 -0400 2021-11-08T16:00:00-05:00 2021-11-08T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Engineering Solutions to Surgical Pain Management (November 8, 2021 4:30pm) https://events.umich.edu/event/88705 88705-21656857@events.umich.edu Event Begins: Monday, November 8, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Opioid prescribing for pain after surgery is a common practice in western medicine. These medications are an important tool for pain management, however excessive opioid prescribing, especially after surgery, can lead to long-term dependence and medication diversion in our communities. This is a dangerous trend that has contributed to the rise of the opioid epidemic in the United States. Dr. Englesbe and Alex Hallway have spent the last 5 years studying these trends and developing solutions to reduce excessive opioid prescribing in acute care. This talk details their efforts to improve practice at a local and state level through policy, innovation, and interdisciplinary collaboration.

Alex Hallway is a Research Area Specialist affiliated with the Michigan Opioid Prescribing Engagement Network and the Michigan Surgical Quality Collaborative (MSQC). Alex studied Human Biology and Supply Chain Management at Michigan State University. He has worked on patient care and quality improvement initiatives at Michigan Medicine since 2017. As the Pain-control Optimization Pathway Lead, Alex works with Blue Cross Blue Shield of Michigan and the MSQC to promote surgical pain control innovation in Michigan hospitals. Alex also leads the MSQC Prehabilitation program, which aims to collect novel preoperative data elements and optimize patient health prior to surgery. Alex is passionate about surgical process optimization using technology and lean thinking. He enjoys working at the intersection of quality improvement and research and has published his work in journals such as JAMA Surgery, The Journal of the American College of Surgeons, and JAMA Network OPEN.

Michael Englesbe, MD, FACS is the Cyrenus G. Darling Sr., MD and Cyrenus G. Darling Jr., MD Professor of Surgery at the University of Michigan in the Section of Transplantation Surgery. Dr. Englesbe received his undergraduate degree at Yale University in New Haven, Connecticut in 1993. He went on to obtain his medical degree in 1997 from the Robert Wood Johnson Medical School and completed his general surgery residency at the University of Michigan Health System in 2004. From 2000 to 2002, Dr. Englesbe did a surgical research post-doctoral fellowship at the University of Washington Medical Center in Seattle, Washington. Dr. Englesbe specializes in kidney and liver transplantation in adults and children. He has a specific expertise in portal hypertension in children and adults.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 27 Oct 2021 11:44:51 -0400 2021-11-08T16:30:00-05:00 2021-11-08T17:30:00-05:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Alexander K. Hallway and Mike Englesbe, MD
Economic History: (November 9, 2021 2:30am) https://events.umich.edu/event/88448 88448-21654117@events.umich.edu Event Begins: Tuesday, November 9, 2021 2:30am
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Wed, 20 Oct 2021 09:50:04 -0400 2021-11-09T02:30:00-05:00 2021-11-09T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Per- and Polyfluoroalkyl Substances (PFAS) and Women’s Reproductive Health: Findings from the Study of Women’s Health Across the Nation (SWAN) (November 9, 2021 12:00pm) https://events.umich.edu/event/88884 88884-21658815@events.umich.edu Event Begins: Tuesday, November 9, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

https://umich.zoom.us/s/97831201308

Dr. Ding is a postdoctoral research fellow focusing on environmental epidemiology in the Department of Epidemiology, School of Public Health, University of Michigan.

The goal of the environmental research seminar/webinar is to provide an interdisciplinary forum for sharing and critiquing research proposals and preliminary study results.

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Lecture / Discussion Tue, 02 Nov 2021 10:04:20 -0400 2021-11-09T12:00:00-05:00 2021-11-09T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Ning Ding ER Seminar (11-09-2021)
Department of Computational Medicine & Bioinformatics Weekly Seminar (November 10, 2021 4:00pm) https://events.umich.edu/event/88540 88540-21654960@events.umich.edu Event Begins: Wednesday, November 10, 2021 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

Subspace classifiers have been around for a long time, beginning with feature selection, which in essence was a subspace selection technique. This talk will discuss the kind of subspace classifiers that Bledsoe and Browning presented in their 1959 paper and from which there have been a variety of extensions which we will discuss.

The Bledsoe and Browning subspace classifier quantizes measurement space. Each quantized observation tuple corresponds to a cell in measurement space. A collection of subspaces are selected at random. In the original form the subspaces were mutually exclusive. For each class, each cell of a subspace contained a number dependent on the number of observations of the training data that fell into that cell. For each class those numbers were combined in ways not dissimilar to random forests. For a given observation tuple, the class with the highest vote count was selected as the assigned class.

We will discuss a variety of principled extensions of the technique and make some comparisons with Neural Networks.

Research Interests:

High-dimensional space clustering, pattern recognition, knowledge discovery and artificial intelligence

Professor Haralick began his work as one of the principal investigators of the NASA ERTS satellite data doing remote sensing image analysis.

He has made a series of contributions in the field of computer vision. In the high-level vision area, he has worked on inferring 3D geometry from one or more perspective projection views.] He has also identified a variety of vision problems which are special cases of the consistent labeling problem. His papers on consistent labeling, arrangements, relation homomorphism, matching, and tree search translate some specific computer vision problems to the more general combinatorial consistent labeling problem and then discuss the theory of the look-ahead operators that speed up the tree search. The most basic of these is called Forward Checking. This gives a framework for the control structure required in high-level vision problems. He has also extended the forward-checking tree search technique to propositional logic.

Zoom: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Livestream / Virtual Fri, 22 Oct 2021 09:28:27 -0400 2021-11-10T16:00:00-05:00 2021-11-10T17:00:00-05:00 Off Campus Location DCMB Seminar Series Livestream / Virtual Robert M. Haralick, PhD (City University of New York)
Michael Beauregard Seminar in Macroeconomics: Capital Heterogeneity and Investment Prices: How much (November 10, 2021 4:00pm) https://events.umich.edu/event/87746 87746-21645517@events.umich.edu Event Begins: Wednesday, November 10, 2021 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Abstract:
Investment-specific technological change (ISTC), reflected in the declining price of new investment goods, has been recognized as an important potential driver of economic growth, business cycles, the labor share, and the equilibrium real rate. However, the changes in investment prices are heavily concentrated in a few capital categories, most notably computers, while most categories exhibit little change. How one aggregates these price changes is hence critical to evaluating the aggregate importance of ISTC. We demonstrate theoretically the correct aggregation approach using a simple standard neoclassical model with multiple capital goods. Importantly, the correct aggregation depends on the question at stake. Second, empirically, we evaluate the quantitative impact of using the correct aggregation procedure. We find that the contribution of ISTC to long-run growth, to business cycles, and to the labor share is smaller than if one ignores aggregation issues.

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Workshop / Seminar Thu, 30 Sep 2021 15:28:16 -0400 2021-11-10T16:00:00-05:00 2021-11-10T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Economic Development and International Economics: (November 11, 2021 4:00pm) https://events.umich.edu/event/88455 88455-21654141@events.umich.edu Event Begins: Thursday, November 11, 2021 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Wed, 20 Oct 2021 10:20:46 -0400 2021-11-11T16:00:00-05:00 2021-11-11T17:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Economic Theory: (November 12, 2021 9:00am) https://events.umich.edu/event/88904 88904-21658895@events.umich.edu Event Begins: Friday, November 12, 2021 9:00am
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 13:44:50 -0400 2021-11-12T09:00:00-05:00 2021-11-12T10:20:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Applied Microeconomics Industrial Organization and Labor Economics: Aftermarket Frictions and the Cost of Off-Platform Options in Centralized Assignment Mechanisms (November 12, 2021 10:00am) https://events.umich.edu/event/88895 88895-21658831@events.umich.edu Event Begins: Friday, November 12, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
In many settings, market designers must contend with the presence of firms who participate in the broader game surrounding a market but do not participate in the portion under the designer’s control. In this paper, we study the empirical relevance of the configuration of on- and off-platform options in the context of a centralized college-major choice system. We quantify significant negative externalities generated by off-platform options and measure the aftermarket frictions that contribute to generating them in practice. Our empirical application uses administrative data from the centralized assignment system for higher education in Chile and leverages a recent policy change that increased the number of on-platform slots by approximately 40%. We first present a policy analysis which shows that expanding the centralized platform leads students to start college sooner and raises the share of students who graduate within six years. We develop an empirical model of college applications, aftermarket waitlists, and matriculation choices. We estimate the model using students’ ranked-ordered applications, on- and off-platform enrollment, and on-time graduation outcomes. We use the estimated model to quantify welfare impacts, decompose different mechanisms and to conduct counterfactual exercises. We find that when more programs are available on the centralized platform, welfare increases substantially. These externalities are driven by students who receive and decline on-platform offers, and are amplified by substantial frictions in waitlists. Our results indicate that expanding the scope of a higher education platform can have real impacts on welfare and human capital. Importantly, the effects are larger for students from lower SES backgrounds, suggesting the design of platforms can have effects on both efficiency and equity.
* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 09 Nov 2021 09:25:34 -0500 2021-11-12T10:00:00-05:00 2021-11-12T11:20:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: Chun Wang, Associate Professor of Measurement and Statistics, College of Education, University of Washington (November 12, 2021 10:00am) https://events.umich.edu/event/84424 84424-21647193@events.umich.edu Event Begins: Friday, November 12, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Measurement invariance (MI) is a statistical property of measurement which implies that the same construct is measured across different groups, or over time. In high-stakes assessments that measure students’ understanding and mastery of disciplinary concepts, measurement invariance is also regarded as an important facet of test fairness. Statistical methods for evaluating measurement invariance originate from Mantel-Haenszel chi-square statistics and flourish within the item response theory (IRT) framework. In this talk, I will introduce a latent regression with regularization method as an emerging approach for evaluating MI. This new method is particularly tuned for two scenarios: (1) a test measures multiple correlated domains, and (2) a digital-first adaptive assessment with automatic item generation. It will be shown that the new method can simultaneously detect measurement non-invariance in multiple items caused by multiple factors in both scenarios.


Chun Wang is an Associate Professor of measurement and statistics in the College of Education at the University of Washington (UW). She is also an affiliated faculty of the Center for Statistics and the Social Sciences at UW. Her research focuses on psychometric models and methods around educational and psychological measurement, including multidimensional and multilevel item response theory models and applications, cognitive diagnostic modeling and computerized adaptive testing. She is the Associate Editor of the Applied Psychological Measurement, British Journal of Mathematical and Statistical Psychology, and the Journal of Educational and Behavioral Statistics.

https://stat.uw.edu/about-us/people/chun-wang

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Workshop / Seminar Mon, 25 Oct 2021 08:42:25 -0400 2021-11-12T10:00:00-05:00 2021-11-12T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Chun Wang
Economics at Work (November 12, 2021 1:00pm) https://events.umich.edu/event/87791 87791-21645953@events.umich.edu Event Begins: Friday, November 12, 2021 1:00pm
Location: Lorch Hall
Organized By: Department of Economics

Economics@Work is intended for any student who is interested in learning about a variety of career opportunities for economics majors. Early students of economics may use this class to explore whether an economics major best suits their interests and goals. Advanced students in economics will benefit from the information and networking opportunities.

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Workshop / Seminar Wed, 10 Nov 2021 10:58:18 -0500 2021-11-12T13:00:00-05:00 2021-11-12T14:30:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Social, Behavioral and Experimental Economics (SBEE) Seminar: Earnings, Fertility and Gender Differences in Choice of Field: Evidence from a Large-Scale Survey and National Administrative Data (November 15, 2021 11:30am) https://events.umich.edu/event/88954 88954-21659304@events.umich.edu Event Begins: Monday, November 15, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
A large literature documents a gender gap in earnings. One area of this literature examines the role of gender differences in choice of field. More recent work argues that a large share of the earnings gap is due to women’s reduced earnings after they have a child. We bring these strands of the literature together by linking gender differences in choice of educational field to differences by field in both expected and realized earnings and fertility. We conduct a large-scale survey experiment among a national sample of college applicants in Denmark. In Denmark, college applicants submit their rank ordered choices of college degree programs to a national clearinghouse that matches students to programs using a strategy proof mechanism based on high school GPA. We survey students about their top-ranked choices after they have submitted their applications but before they learn the results. We elicit beliefs about their experience while studying as well as their labor market and family outcomes ten years after graduation. We then incorporate national administrative data on labor market and family outcomes by degree program from prior cohorts. We use the combined experimental and administrative data to address the following questions: (1) To what extent is there an earnings-fertility tradeoff in more heavily female fields (i.e., lower earnings and higher fertility)? (2) How much of the gender earnings gap is explained by gender differences in choice of degree; and how much by gender differences in the child penalty? And, (3) To what extent do applicants' expectations align with the realized outcomes of prior cohorts?

(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Thu, 04 Nov 2021 13:37:04 -0400 2021-11-15T11:30:00-05:00 2021-11-15T12:45:00-05:00 Off Campus Location Department of Economics Workshop / Seminar SBEE seminar series
Public Finance: (November 15, 2021 4:00pm) https://events.umich.edu/event/88902 88902-21658893@events.umich.edu Event Begins: Monday, November 15, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 13:37:01 -0400 2021-11-15T16:00:00-05:00 2021-11-15T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Disabusing Disability™: Demonstrating That DISability Doesn’t Mean INability (November 15, 2021 4:30pm) https://events.umich.edu/event/89183 89183-21660946@events.umich.edu Event Begins: Monday, November 15, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Disability is regularly neglected in conversations about diversity, equity, and inclusion, yet it is the one demographic that we may all identify with one day. Therefore, disability should serve as a means of demonstrating that we are all much more similar than we are different. As a disabled, black, Nigerian, immigrant, cis-gender heterosexual, male, physician, athlete this presentation will talk about the intersectionality between all of those identities, striving to demonstrate that disability is not inability, and encouraging us to allow people to demonstrate what they can do, rather than attempting to limit them based on what they cant. It will also hope to engage you all in conversation about what each of us can do, within our own spheres of influence to make sure we are not perpetuating ableism in our personal, academic, and professional lives.

Dr. Oluwaferanmi Okanlami is an Assistant Professor of Family Medicine, Physical Medicine & Rehabilitation, and Urology at Michigan Medicine, an Adjunct Assistant Professor of Orthopaedic Surgery at David Geffen School of Medicine at UCLA, and the Director of Student Accessibility and Accommodation Services at the University of Michigan, where he oversees the office of Services for Students with Disabilities, two Testing Accommodation Centers, and the Adaptive Sports & Fitness Program. He also serves as the Spokesperson for Guardian Life in their Equal & Able Partnership.

“Dr. O” was born in Nigeria before immigrating to the US at a young age. He attended High School at Deerfield Academy and college at Stanford University where he also ran Track & Field, serving as captain his last two seasons and achieving Academic All American recognition.

He then earned his MD from the University of Michigan before matching into Orthopedic Surgery at Yale. At the beginning of his 3rd year, he experienced a spinal cord injury, paralyzing him from the chest down. After two surgeries and intense rehabilitation, he was blessed with some return of motor function, and navigates the world as a proud wheelchair user, managing the other long-term sequelae of an incomplete cervical spinal cord injury.

He went on to earn a Master’s in Engineering, Science, and Technology Entrepreneurship from The University of Notre Dame, and completed his Family Medicine Residency at Memorial Hospital in South Bend, Indiana. He served on the St. Joseph County Board of Health, appointed by (former South Bend Mayor, and current Secretary of the Department of Transportation) Pete Buttigieg; and is on the board of the River City Challenged Athletes, a non-profit supporting the area adaptive sports teams. He was featured on Robin Robert’s Good Morning America Series “Thriver Thursday,” and has a catchphrase, “Disabusing Disability®,” hoping to demonstrate that DISability doesn’t mean INability. He is a member of the Alpha Omega Alpha Medical Honors Society, received Michigan Medicine’s Distinguished Early Career Alumni Award in 2020, and was given the “A Teacher’s Teacher Award’’ by the Academy of Medical Educators.

Nationally, he serves as the Disability Issues representative on the Steering Committee for the Group on Diversity and Inclusion at the AAMC, and sits on the National Medical Association’s Council on Medical Legislation. He speaks around the country on topics related to Diversity, Equity, and Inclusion, including, but not limited to creating a health system that is accessible to and inclusive of both patients and providers with disabilities, and providing reasonable and appropriate accommodations for students with disabilities in higher education. He has been featured on CBS News, PBS News Hour, and MSNBC’s Morning Joe, and is passionate about adaptive sports and fitness, striving to provide access to physical fitness and inclusive recreational and competitive sports for all.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 11 Nov 2021 16:13:02 -0500 2021-11-15T16:30:00-05:00 2021-11-15T17:30:00-05:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Oluwaferanmi O. Okanlami, M.D., M.S.
Economic History: (November 16, 2021 2:30pm) https://events.umich.edu/event/88450 88450-21654120@events.umich.edu Event Begins: Tuesday, November 16, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Wed, 20 Oct 2021 09:58:52 -0400 2021-11-16T14:30:00-05:00 2021-11-16T16:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
ISR-Zwerdling Seminar in Labor Economics: (November 17, 2021 2:30pm) https://events.umich.edu/event/88428 88428-21653874@events.umich.edu Event Begins: Wednesday, November 17, 2021 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come

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Workshop / Seminar Tue, 19 Oct 2021 16:42:07 -0400 2021-11-17T14:30:00-05:00 2021-11-17T15:50:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
MIPSE Seminar | The Plasma-Water Interface: Modern Challenges and New Software Tools (November 17, 2021 3:30pm) https://events.umich.edu/event/86297 86297-21632605@events.umich.edu Event Begins: Wednesday, November 17, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The interaction of low-temperature plasmas with liquid water is a fundamental problem in many applications, from plasma medicine to chemical processing, and more generally where the generation of reactive oxygen and nitrogen species and/or of solvated electrons is of utmost importance. However, characterization of the plasma-liquid interface presents several challenges, both experimentally and computationally, due to the multiscale and multiphysics nature of the problem. In this seminar we provide an overview of recent modeling developments on plasma-liquid interfaces, presenting the new software package Zapdos-CRANE, based on the MOOSE finite-element framework. We provide a brief overview of the software, showing few case studies of interest. The model was used to study a humid argon DC plasma over a water surface, operated in both cathodic and anodic modes. In this system, one of the reactions of interest is the formation and dissolution of hydroxide (OH) radicals, which subsequently produce hydrogen peroxide. The model allows the investigation of the main plasma-chemistry reaction mechanisms for peroxide production with the plasma. The analysis reveals that hydrogen peroxide is increased during anodic plasma treatment due to elevated water vapor dissociation reactions near the interface. Finally, the role of solvated electrons generated during cathodic plasma operations is discussed, showing how they directly degrade hydrogen peroxide in the aqueous phase, inhibiting its accumulation.

About the Speaker:
Davide Curreli is Associate Professor in the Department of Nuclear, Plasma, and Radiological Engineering at the University of Illinois Urbana-Champaign, and at the National Center for Supercomputing Applications. Dr. Curreli leads the Laboratory for Computational Plasma Physics at Illinois. His research activities focus on computational modeling of plasma material interactions and plasma chemistry of low-temperature plasmas for fusion and nuclear applications. Among his current research activities, Dr. Curreli is coordinator of the Nuclear Fireball Plasma Chemistry activities within the University Research Alliance funded by DOD DTRA. His group actively works on multiple projects in Fusion Energy Sciences. Dr. Curreli is Donald Biggar Willett Faculty Scholar at the University of Illinois.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:44:13 -0400 2021-11-17T15:30:00-05:00 2021-11-17T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Davide Curreli
DCMB / CCMB Weekly Seminar Series (November 17, 2021 4:00pm) https://events.umich.edu/event/89137 89137-21660643@events.umich.edu Event Begins: Wednesday, November 17, 2021 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Talk title: Clinical Trajectory analysis to determine risk-factors of Copd: A COPDGene Study

Abstract:

Background

Chronic obstructive pulmonary disease (COPD) presents significant clinical heterogeneity and a wide variety of progression trajectories [1]. Clinical trajectory analysis (ClinTrajAn) is a powerful tool based on elastic principal graphs for the calculation of trajectories from large cross-sectional clinical data sets [2].

Aims and objectives

Our objective was to determine potential risk-factors by evaluate progression trajectories in COPD using ClinTrajAn on the COPDGene Phase I (baseline visit) dataset.

Methods

7883 participants, current and former smokers with GOLD 0 thru 4 COPD, from Phase I of the COPDGene study, were utilized for this work. 55 features were obtained for each subject, including demographics, spirometry, smoking history and computed tomography (CT), which included Parametric Response Mapping (PRM). Developed by our group, PRM is capable of simultaneously measuring small airways disease and emphysema which are the main contributors of airflow limitations in COPD. The resulting data matrix was analyzed with ClinTrajAn.

Results

A principal tree, with 13 branch segments and 8 termini, was generated (Figure 1). There was a clearly recognized trajectory from healthier subjects through decreasing lung function and increasing age (Figure 1 A), increasing in GOLD (Figure 1 B), to an emphysema high terminus (Figure 1 C). Notably this method illustrated numerous branching points along this trajectory.

Conclusions

In this study we used ClinTrajAn to obtain a map of disease progression trajectories in COPD including clinically recognized pathogenesis. Our next steps will be to further validate this approach using longitudinal data from the COPDGene follow-up visits.

References

1. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, MacNee W, Make BJ. Chronic obstructive pulmonary disease phenotypes: the future of COPD. American journal of respiratory and critical care medicine. 2010 Sep 1;182(5):598-604.

2. Golovenkin SE, Bac J, Chervov A, Mirkes EM, Orlova YV, Barillot E, Gorban AN, Zinovyev A. Trajectories, bifurcations, and pseudo-time in large clinical datasets: applications to myocardial infarction and diabetes data. GigaScience. 2020 Nov;9(11):giaa128.

Zoom link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Wed, 10 Nov 2021 09:47:40 -0500 2021-11-17T16:00:00-05:00 2021-11-17T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion
Michael Beauregard Seminar in Macroeconomics: (November 17, 2021 4:00pm) https://events.umich.edu/event/88898 88898-21658834@events.umich.edu Event Begins: Wednesday, November 17, 2021 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 11:54:23 -0400 2021-11-17T16:00:00-05:00 2021-11-17T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Econometrics: (November 18, 2021 2:30pm) https://events.umich.edu/event/88896 88896-21658832@events.umich.edu Event Begins: Thursday, November 18, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

*To join the seminar, please contact: econometrics-seminar-requests@umich.edu

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Workshop / Seminar Tue, 02 Nov 2021 11:45:25 -0400 2021-11-18T14:30:00-05:00 2021-11-18T16:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: John Paisley, Associate Professor, Department of Electrical Engineering, Columbia University (November 19, 2021 10:00am) https://events.umich.edu/event/84425 84425-21623927@events.umich.edu Event Begins: Friday, November 19, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Models of sequential data such as the recurrent neural network (RNN) often implicitly treat a sequence as having a fixed time interval between observations and do not account for group-level effects when multiple sequences are observed. We propose a model for grouped sequential data based on the RNN that accounts for varying time intervals between observations in a sequence by learning a group-level parameter to which each sequence reverts as more time passes between observations. Our approach is motivated by the mixed membership framework, and can be used for dynamic topic modeling-type problems in which the distribution on topics (not the topics themselves) are evolving in time. We demonstrate our approach on two datasets: The Instacart set of 3.4 million online grocery orders made by 206K customers, and a UK retail set consisting of over 500K orders.

Bio: John Paisley is an Associate Professor in the Department of Electrical Engineering at Columbia University, where he is also a member of the Data Science Institute. He received his Ph.D. in Electrical and Computer Engineering from Duke University. His research interests include Bayesian modeling and inference techniques, Bayesian nonparametric methods, and their applications to a variety of machine learning problems.

http://www.columbia.edu/~jwp2128/

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Workshop / Seminar Fri, 12 Nov 2021 16:26:49 -0500 2021-11-19T10:00:00-05:00 2021-11-19T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Paisley
Process Mining Approaches to Identify System-Level Factors in Maternal Health Disparities (November 22, 2021 4:30pm) https://events.umich.edu/event/88862 88862-21658653@events.umich.edu Event Begins: Monday, November 22, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

The US has one of the highest maternal mortality and morbidity rates among all developed countries despite spending the most on maternity care. Half of all maternal deaths, Severe Maternal Morbidity (SMM), and near-misses are preventable with timely and appropriate care. Maternal mortality and SMM from several specific conditions, such as hemorrhage and preeclampsia, have much higher rates of preventability. Socioeconomic factors have been shown to impact maternal outcomes, however, there is little research explicitly examining system-level factors such as delays, missed or late diagnoses, inadequate teamwork, delays, and poor coordination within the health system that contribute to these adverse outcomes and disparities. National and state level efforts to improve maternal care has led to the development of best practices in maternity care pathways however many challenges still exist. Examining patients’ journey through the health system will also enable us to identify, and ultimately predict, specific system features associated with adverse outcomes. This research approaches the care pathway analysis within the lens of process mining. Process mining evaluates the processes using event logs. The patient cohort consists of medical records for maternal patients who have initiated prenatal care and postpartum women with normal birth outcomes and adverse maternal outcomes. We used NIH’s “AllofUS” dataset to develop a conceptual model to map maternal patients’ interactions with the healthcare system. Process mining algorithms help us identify variability in these captured care pathways that are associated with adverse maternal outcomes. Preliminary data analysis using visualization and decision tree techniques offer insights about disparities in maternal care.

Dr. Sreenath Chalil Madathil is an Assistant Professor in the Industrial Manufacturing and Systems Engineering (IMSE) at The University of Texas at El Paso (UTEP). Before joining UTEP, he worked as research scientist at the Watson Institute of Systems Excellence at The Research Foundation of the State University of New York at Binghamton. Dr. Chalil Madathil received his Ph.D. and MS in Industrial Engineering from Clemson University. His current research interest is in applying operations research and data analytics to healthcare and supply chain domains. He is a member of the Institute of Industrial & Systems Engineers (IISE), and serves as chair for the IISE Health Systems Track. He is also a member of INFORMS, and Alpha Pi Mu.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Mon, 01 Nov 2021 14:58:16 -0400 2021-11-22T16:30:00-05:00 2021-11-22T17:30:00-05:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Sreenath Chalil Madathil, Ph.D.
Sustaining a Healthy Nail Salon Workforce in Michigan (November 23, 2021 12:00pm) https://events.umich.edu/event/89270 89270-21661657@events.umich.edu Event Begins: Tuesday, November 23, 2021 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Registration required
https://umich.zoom.us/s/98595068138

Aurora Le, PhD, MPH, CPH, CSP (John G. Searle Assistant Professor of Environmental Health Sciences, School of Public Health, University of Michigan) and Marie-Anne Rosemberg, PhD, MN, RN, FAAOHN (Assistant Professor, Dept. of Systems, Populations and Leadership, School of Nursing, University of Michigan), co-lead the Michigan Healthy Nail Salon Cooperative. The goal of the environmental research seminar/webinar is to provide an interdisciplinary forum for sharing and critiquing research proposals and preliminary study results.

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Lecture / Discussion Mon, 15 Nov 2021 13:38:28 -0500 2021-11-23T12:00:00-05:00 2021-11-23T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Nov 30 Environmental Research Webinar
Social, Behavioral and Experimental Economics (SBEE) Seminar: The Supply of Motivated Beliefs (November 29, 2021 11:30am) https://events.umich.edu/event/88956 88956-21659307@events.umich.edu Event Begins: Monday, November 29, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Thu, 04 Nov 2021 08:59:24 -0400 2021-11-29T11:30:00-05:00 2021-11-29T12:45:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Social, Behavioral and Experimental Economics (SBEE) Seminar: The Supply of Motivated Beliefs (November 29, 2021 11:30am) https://events.umich.edu/event/89140 89140-21660645@events.umich.edu Event Begins: Monday, November 29, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
When people choose what messages to send to others, they often consider how others will interpret the messages. In many environments, particularly in politics, message receivers engage in motivated reasoning, distorting how they process information in directions they find more attractive. This paper uses two online experiments to study what information senders choose to send to receivers on topics that evoke politically-motivated beliefs. Experiment 1, conducted using a sample of social media users, studies the effect of incentivizing senders to be perceived as truthful. These incentives cause senders to send less truthful messages. With these incentives, senders send more false information when it aligns with receivers' motivated beliefs, even controlling for receivers' current beliefs. Receivers do not anticipate the adverse effects of senders' incentives. Experiment 2 isolates the role that motivated reasoning plays by constructing an environment in which receivers assess the truthfulness of messages from a computer and senders choose which message to be paid for. Senders predict that politically-motivated reasoning impacts receivers' inference, they demand information about receivers' political preferences, and they use the receivers' politics to strategically choose less truthful computer messages.
(To attend this online event, please complete the form to receive email instructions and announcements for this and future SBEE Seminars.)

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Workshop / Seminar Wed, 10 Nov 2021 11:03:11 -0500 2021-11-29T11:30:00-05:00 2021-11-29T12:45:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Cognitive Science Seminar Series: Computational models of classical conditioning (November 29, 2021 2:30pm) https://events.umich.edu/event/88994 88994-21659581@events.umich.edu Event Begins: Monday, November 29, 2021 2:30pm
Location: Off Campus Location
Organized By: Weinberg Institute for Cognitive Science

The Cognitive Science Seminar Series welcomes guest presenter Shreya Karippurathu Rajagopal, who will give a talk titled "Towards Building a Comprehensive Computational Model of Classical Conditioning."

All cognitive science seminars will be virtual this semester. For Zoom passcode information, or to be added to the seminar distribution list, please email cogsci-seminar-requests@umich.edu.

ABSTRACT
Classical conditioning is a way of learning about one’s environment wherein a previously neutral stimulus (conditioned stimulus - CS) gets associated with another stimulus that evokes natural reward (unconditioned stimulus - US). Over several trials informing this pairing, the animal begins to generate a response (Conditioned response - CR) when only the CS is present. Classical Conditioning as a field encompasses a host of known phenomena about how the CR is affected by manipulating a range of factors in an experiment - the interstimulus interval, the number of CS-s, the order in which CS-s appear, etc. A key challenge in the field is to build a comprehensive computational model that can explain all these phenomena.

We approached this problem by familiarizing ourselves with some of the most prominent models of classical conditioning as of today so as to understand their shortcomings and build on them. The talk will go into the details of the temporal difference model of classical conditioning (Ludvig et. al 2012) and our attempts in replicating this model. It will also briefly touch upon other well-accepted models and our tentative plan for the project going forward.

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Lecture / Discussion Mon, 29 Nov 2021 09:22:20 -0500 2021-11-29T14:30:00-05:00 2021-11-29T15:50:00-05:00 Off Campus Location Weinberg Institute for Cognitive Science Lecture / Discussion
Public Finance: Optimal Paternalistic Savings Policies (November 29, 2021 4:00pm) https://events.umich.edu/event/87991 87991-21648231@events.umich.edu Event Begins: Monday, November 29, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We study optimal savings policies when there is a dual concern about undersaving for retirement and income inequality. Agents differ in present bias and earnings ability, both unobservable to a planner with paternalistic and redistributive motives. We characterize the solution to this two-dimensional screening problem and provide a decentralization using realistic policy instruments: mandatory savings at low incomes but a choice between subsidized savings vehicles at high incomes--resembling Social Security, 401(k) and IRA accounts in the US. Offering more savings choice at higher incomes facilitates redistribution. To solve large-scale versions of this problem numerically, we propose a general, computationally stable, and efficient active-set algorithm. Relative to the current US retirement system, we find significant welfare gains from increasing mandatory savings and limiting savings choice at low incomes.

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Workshop / Seminar Wed, 06 Oct 2021 15:20:25 -0400 2021-11-29T16:00:00-05:00 2021-11-29T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
The Role of Command Centers in Health System Operations (November 29, 2021 4:30pm) https://events.umich.edu/event/89361 89361-21662306@events.umich.edu Event Begins: Monday, November 29, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Hospitals nationally have struggled with the challenges of increasing demand and limited overall capacity leading to bottlenecks in care and inefficient patient flow through the hospital. Given constraints on expanding bed capacity including both high costs and regulatory barriers, hospitals have increasingly focused on improving operational efficiency as a method to improve patient flow. Michigan Medicine and UM Health have been on a journey to improve patient flow over several years through the application of engineering principles, analytics, improved management of variation, and creation of a system-wide playbook for how we approach capacity management and patient flow in our hospitals. This work has culminated in a current project to develop and implement a hospital command center as the next step in creating reliable system-wide processes to manage patient flow and safety. In this talk, I will describe our journey in hospital capacity management, walk through our playbook and principles and finish with an update on how we are planning to integrate all these lessons learned into our new hospital command center that will go live in late 2022.

Vikas I. Parekh, MD is Professor of Medicine at the University of Michigan where he is the Associate Chief Medical Officer for UM Health. As Associate Chief Medical officer, he guides the health system’s work on capacity management, readmissions and leads an operational analytics team working to optimize patient flow and operational challenges throughout the health system as lead for the multi-million-dollar Command Center project. He has published and presented nationally in the fields of hospital medicine, residency education and hospital operations and capacity management. Dr. Parekh is a graduate of the Harvard Medical School and completed his residency training at the University of Michigan. Dr. Parekh has won several awards including the Provost’s Teaching Innovation Prize, the Special Recognition Award for Contributions to the House Officer Teaching Program, the H. Marvin Pollard Award, the Department of Medicine’s highest award for resident teaching and the Chair’s Impact Award for his work during COVID-19 and was inducted into the Medical School’s League of Educational Excellence.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Thu, 18 Nov 2021 10:24:55 -0500 2021-11-29T16:30:00-05:00 2021-11-29T17:30:00-05:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Vikas Parekh, MD
Autonomous and Connected Vehicle Safety (November 30, 2021 2:00pm) https://events.umich.edu/event/89138 89138-21660642@events.umich.edu Event Begins: Tuesday, November 30, 2021 2:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

A significant, persisting challenge in transportation is traffic safety which, despite a decrease in vehicle miles traveled (VMT), led to 38,680 deaths and over 2.8 million injuries in the United States last year. Traffic crashes also result in an estimated economic loss of over $230 billion annually. Integrated vehicle passive and active safety systems and connectivity are required to mitigate crashes or avoid collisions.

For the final Distinguished Lecture Series of 2021, the Center for Connected and Automated Transportation (CCAT) is pleased to welcome Dr. Azim Eskandarian to review some timely research areas on vehicle control systems, signal processing, and communication-enabled connectivity to address the pervasive vehicle safety problem. Dr. Eskandarian will also discuss a holistic approach to vehicular safety and its advanced research challenges, including connectivity, ranging from partial to full autonomy and collision avoidance implications. Attendees will see a critical perspective on personal mobility and the future of driving that ensures safety and congestion mitigation while minimizing energy consumption.

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Livestream / Virtual Wed, 10 Nov 2021 09:40:57 -0500 2021-11-30T14:00:00-05:00 2021-11-30T15:00:00-05:00 Off Campus Location Center for Connected and Automated Transportation Livestream / Virtual Decorative Image for the CCAT Distinguished Lecture Series with Professor Azim Eskandiarian. It features the presentation title 'Autonomous and Connected Vehicle Safety', Professor Eskandarian's headshot, and an animated image of a smart intersection.
Economic History: (November 30, 2021 2:30pm) https://events.umich.edu/event/88897 88897-21658833@events.umich.edu Event Begins: Tuesday, November 30, 2021 2:30pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 02 Nov 2021 11:50:18 -0400 2021-11-30T14:30:00-05:00 2021-11-30T16:00:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Department of Computational Medicine & Bioinformatics Weekly Seminar (December 1, 2021 4:00pm) https://events.umich.edu/event/88514 88514-21654664@events.umich.edu Event Begins: Wednesday, December 1, 2021 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract:

Epigenetic control of gene expression is highly cell-type- and context-specific. Yet, despite its complexity, gene regulatory logic can be broken down into modular components consisting of a transcription factor (TF) activating or repressing the expression of a target gene through its binding to a cis-regulatory region. Recent advances in joint profiling of transcription and chromatin accessibility with single-cell resolution offer unprecedented opportunities to interrogate such regulatory logic. Here, we propose a nonparametric approach, TRIPOD, to detect and characterize three-way relationships between a TF, its target gene, and the accessibility of the TF’s binding site, using single-cell RNA and ATAC multiomic data. We apply TRIPOD to interrogate cell-type-specific regulatory logic in peripheral blood mononuclear cells and contrast our results to detections from enhancer databases, cis-eQTL studies, ChIP-seq experiments, and TF knockdown/knockout studies. We then apply TRIPOD to mouse embryonic brain data during neurogenesis and gliogenesis and identified known and novel putative regulatory relationships, validated by ChIP-seq and PLAC-seq. Finally, we demonstrate TRIPOD on SHARE-seq data of differentiating mouse hair follicle cells and identify lineage-specific regulation supported by histone marks for gene activation and super-enhancer annotations.

Hosted by: Joshua Welch, PhD

Speaker will be in-person and the seminar will be live-streamed via Zoom.

Zoom: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Thu, 21 Oct 2021 14:55:35 -0400 2021-12-01T16:00:00-05:00 2021-12-01T17:00:00-05:00 Palmer Commons DCMB Seminar Series Lecture / Discussion Yuchao Jiang (Assistant Professor in the Departments of Biostatistics and Genetics at UNC)
Macroeconomics and Labor Joint Seminar: (December 1, 2021 4:00pm) https://events.umich.edu/event/89618 89618-21664566@events.umich.edu Event Begins: Wednesday, December 1, 2021 4:00pm
Location: Lorch Hall
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 30 Nov 2021 13:23:25 -0500 2021-12-01T16:00:00-05:00 2021-12-01T17:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Michigan Program in Survey and Data Science Information Session (December 2, 2021 11:00am) https://events.umich.edu/event/89094 89094-21660472@events.umich.edu Event Begins: Thursday, December 2, 2021 11:00am
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

Michigan Program in Survey and Data Science (MPSDS) offers graduate degrees that combine ideas and techniques for producing and analyzing data about humans and our society. Join us to launch your career in this exciting and rewarding field in which scientists interpret the world through data.
Visit our website: https://surveydatascience.isr.umich.edu/ for detailed information.

Advance registration is required, https://umich.zoom.us/webinar/register/4716359688195/WN_MSEcVDFwQT2eQhNyK0sw8Q

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Presentation Tue, 09 Nov 2021 10:41:54 -0500 2021-12-02T11:00:00-05:00 2021-12-02T12:00:00-05:00 Off Campus Location Michigan Program in Survey and Data Science Presentation info session flyer
Econometrics: Adversarial machine learning and instrumental variables for flexible causal modeling (December 2, 2021 2:30pm) https://events.umich.edu/event/89547 89547-21664067@events.umich.edu Event Begins: Thursday, December 2, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
Machine learning models are increasingly being used to automate decision-making in a multitude of domains. Making good decisions requires uncovering causal relationships from data. Many causal estimation problems reduce to estimating a model that satisfies a set of conditional moment restrictions. We develop an approach for estimating flexible models defined via conditional moment restrictions, with a prototypical application being non-parametric instrumental variable regression. We introduce a min-max criterion function, under which the estimation problem can be thought of as solving a zero-sum game between a modeler who is optimizing over the hypothesis space of the target causal model and an adversary who identifies violating moments over a test function space. We analyze the statistical estimation rate of the resulting estimator for arbitrary hypothesis spaces, with respect to an appropriate analogue of the mean squared error metric, for ill-posed inverse problems. We show that when the minimax criterion is regularized with a second moment penalty on the test function and the test function space is sufficiently rich, then the estimation rate scales with the critical radius of the hypothesis and test function spaces, a quantity which typically gives tight fast rates. Our main result follows from a novel localized Rademacher analysis of statistical learning problems defined via minimax objectives. We provide applications of our main results for several hypothesis spaces used in practice such as: reproducing kernel Hilbert spaces, high dimensional sparse linear functions, spaces defined via shape constraints, ensemble estimators such as random forests, and neural networks. For each of these applications we provide computationally efficient optimization methods for solving the corresponding minimax problem and stochastic first-order heuristics for neural networks.
Based on joint works with: Nishanth Dikkala, Greg Lewis and Lester Mackey

*To join the seminar, please contact: econometrics-seminar-requests@umich.edu

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Workshop / Seminar Mon, 29 Nov 2021 12:03:35 -0500 2021-12-02T14:30:00-05:00 2021-12-02T15:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: Lester Mackey, Machine Learning Researcher, Microsoft Research New England, Adjunct Professor, Department of Statistics, Stanford University (December 3, 2021 10:00am) https://events.umich.edu/event/84426 84426-21623928@events.umich.edu Event Begins: Friday, December 3, 2021 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: This talk will introduce two new tools for summarizing a probability distribution more effectively than independent sampling or standard Markov chain Monte Carlo thinning:

1) Given an initial n point summary (for example, from independent sampling or a Markov chain), kernel thinning finds a subset of only square-root n points with comparable worst-case integration error across a reproducing kernel Hilbert space.

2) If the initial summary suffers from biases due to off-target sampling, tempering, or burn-in, Stein thinning simultaneously compresses the summary and improves the accuracy by correcting for these biases.

These tools are especially well-suited for tasks that incur substantial downstream computation costs per summary point like organ and tissue modeling in which each simulation consumes 1000s of CPU hours.


Lester Mackey is a statistical machine learning researcher at Microsoft Research New England and an adjunct professor at Stanford University. His current research interests include statistical machine learning, scalable algorithms, high-dimensional statistics, approximate inference, and probability. Lately, he has been developing and analyzing scalable learning algorithms for healthcare, climate forecasting, approximate posterior inference, high-energy physics, recommender systems, and the social good.

https://web.stanford.edu/~lmackey/

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Workshop / Seminar Mon, 29 Nov 2021 14:47:05 -0500 2021-12-03T10:00:00-05:00 2021-12-03T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Lester Mackey
NMR and bioinformatic approaches to understanding how intrinsically disordered proteins modulate biomolecular condensates (December 3, 2021 12:00pm) https://events.umich.edu/event/84690 84690-21624430@events.umich.edu Event Begins: Friday, December 3, 2021 12:00pm
Location:
Organized By: LSA Biophysics

The role of biomolecular condensates in regulating biological function and the importance of dynamic interactions involving intrinsically disordered protein regions (IDRs) in their assembly are increasingly appreciated. Elucidating the critical interactions that govern condensation via phase separation is challenging due to the lack of applicability of standard structural biological tools to study these highly dynamic large-scale associated states and the lack of applicability of standard bioinformatic tools to study low complexity sequences that are not easily alignable. Using the C-terminal IDR (607 to 709) of CAPRIN1, an RNA-binding protein found in cytoplasmic biomolecular condensates, we have applied NMR methods developed by Lewis Kay to obtain site-specific information on key interactions that control phase separation and on the modulation of phase separation by post-translational modifications and ATP. We have developed, with Alan Moses, a bioinformatics approach for IDRs that does not require alignments and that identifies conserved molecular features (such as biophysical properties), termed “evolutionary signatures.” Groups of IDRs with similar evolutionary signatures are highly enriched for functional annotations and phenotypes, including clusters that are strongly linked to particular biomolecular condensates. We can utilize a feature-based approach to understand the types of interactions within specific condensates and how disease mutations that perturb conserved features may drive pathology. We also developed a new phase separation predictive tool based on sequence statistics for different physicochemical interactions within the folded protein database that provides insights into the key interactions underlying condensates. These experimental and computational methods should enable deeper understanding of how IDRs contribute to biological regulation via biomolecular condensates.

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Workshop / Seminar Fri, 05 Nov 2021 14:11:26 -0400 2021-12-03T12:00:00-05:00 2021-12-03T13:00:00-05:00 LSA Biophysics Workshop / Seminar
Social, Behavioral and Experimental Economics (SBEE) Seminar: Cognitive Endurance as Human Capital (December 6, 2021 11:30am) https://events.umich.edu/event/87358 87358-21641514@events.umich.edu Event Begins: Monday, December 6, 2021 11:30am
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We examine the possibility that schooling may build human capital not only by teaching academic content, but by expanding the mind's capacity for cognition itself. We hypothesize that one feature of formal schooling---engaging in effortful thinking for sustained periods---could increase sustained attention: the ability to maintain focus over time. To motivate this idea, we document that globally and in the US, the poor exhibit worse sustained attention than the rich across a variety of field behaviors; they also attend schools that are less likely to require them to engage in concentration. We test our hypothesis using a field experiment with 1,650 low-income Indian primary school students. We assign students to engage in cognitive activity for sustained periods during the school day, using either math content (mimicking good schooling) or non-academic content (providing a pure test of our mechanism). Each approach markedly improves sustained attention across disparate domains: academics, listening, IQ tests, and traditional psychology measures. Moreover, the treatments increase students' regular school performance in Hindi, English, and math. This indicates that simply spending time in effortful thinking---without learning any subject content---substantively improves traditional measures of human capital. Our findings support a broader view of how schooling shapes general human capital, and suggest that worse environments may disadvantage poor children by hampering the development of core cognitive capacity.

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Workshop / Seminar Wed, 22 Sep 2021 10:32:43 -0400 2021-12-06T11:30:00-05:00 2021-12-06T12:45:00-05:00 Off Campus Location Department of Economics Workshop / Seminar SBEE seminar series
Great Lakes Seminar Series (December 6, 2021 2:00pm) https://events.umich.edu/event/89700 89700-21665015@events.umich.edu Event Begins: Monday, December 6, 2021 2:00pm
Location: Off Campus Location
Organized By: Cooperative Institute for Great Lakes Research (CIGLR)

Please join us for a Great Lakes Seminar Series presentation:
Time: 2:00-3:00 pm EST
Location: Virtual
Presenter: Michael McKay – Executive Director and Professor; Great Lakes Institute for Environmental Research; University of Windsor
Title: Life under ice: The rise and fall of Lake Erie’s winter algal bloom

Webinar Registration: https://register.gotowebinar.com/register/1935127688355002379

About the presentation: Ice cover presents a logistical obstacle to our full understanding of function of north temperate ecosystems. Reflecting this, ecosystem models frequently underestimate, or even neglect biological parameters associated with ice cover. Despite the perceived inhospitable environment imposed by cold temperatures and ice cover during winter in Lake Erie, work over the past decade has revealed numerous examples of high biological activity with abundant phytoplankton biomass dominated by psychrophilic, filamentous diatoms. The diatoms are physiologically robust and the diatom bloom persists through early spring, eventually contributing to carbon export in Lake Erie’s central basin. During mild winters, the bloom is reduced, likely due to light limitation coincident with deep wind-aided mixing. These surveys have demonstrated that diatom assemblages possess ice nucleating abilities, a characteristic promoting ice formation and which enables the winter diatoms to maintain a favorable position in the photic zone when the lake is ice covered. Our recent efforts have focused on mechanisms of bloom decline where chytrid parasites and other pathogens are implicated. Broadening the impact of this research has been a unique partnership with the U.S. Coast Guard promoting citizen science in support of winter data collection.

About the speaker: In 2019, Mike McKay joined the University of Windsor where he serves as the Executive Director of the Great Lakes Institute for Environmental Research and Professor in the School of the Environment. Mike received undergraduate- and graduate degrees in Biology from Queen’s University at Kingston and McGill University (Montréal), respectively. Upon completion of his doctoral work, he held postdoctoral fellowships at the University of Alaska Fairbanks and with the University of Delaware where he served concurrently at the Department of Energy’s Brookhaven National Laboratory on Long Island, NY. It was during this period that Mike became active in research on aquatic nutrient cycling through his involvement with the ecosystem-scale ocean iron fertilization projects being conducted by scientific personnel from Brookhaven at that time. Mike’s research expanded to include large lakes on his arrival to Bowling Green State University where he served on the faculty for over 21 years studying the biogeochemical cycling of nutrients, phytoplankton and bacterial community dynamics and more recently, winter limnology involving research coordination with icebreaking programs of Canadian- and U.S. Coast Guards.

Among Mike’s research honors, he was awarded an Alexander von Humboldt Foundation Research Fellowship in 2005 where he was resident at the Helmholtz Centre for Ocean Research Kiel (Germany) and in 2013, was named Visiting Scholar at the Large Lakes Observatory of the University of Minnesota. He is the author of over 95 peer-reviewed manuscripts, is a co-recipient of the 2019 John Martin award from ASLO and currently serves as an Associate Editor for the Journal of Great Lakes Research.

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Lecture / Discussion Thu, 02 Dec 2021 09:35:31 -0500 2021-12-06T14:00:00-05:00 2021-12-06T15:00:00-05:00 Off Campus Location Cooperative Institute for Great Lakes Research (CIGLR) Lecture / Discussion Seminar series flyer
Public Finance: (December 6, 2021 4:00pm) https://events.umich.edu/event/89630 89630-21664581@events.umich.edu Event Begins: Monday, December 6, 2021 4:00pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Tue, 30 Nov 2021 15:53:02 -0500 2021-12-06T16:00:00-05:00 2021-12-06T17:00:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Data Analytics for Public Health Systems (December 6, 2021 4:30pm) https://events.umich.edu/event/89669 89669-21664760@events.umich.edu Event Begins: Monday, December 6, 2021 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: Center for Healthcare Engineering & Patient Safety (CHEPS)

Data collected within the public health system can be used to advance personalized medicine, target interventions, and evaluate guidelines and practices among many others. It can provide opportunities to set up “policy” labs where policies and interventions can be tested without their direct deployment to the public. In this presentation, I will overview data analytics in healthcare within the paradigm of data science, integrating all data processes from data acquisition and processing to data translation, to data modeling and finally decision making. The overarching message is that data science is at the core of informed decisions, interventions, and ultimately at the core of system’s transformations.

Nicoleta Serban is Virginia C. and Joseph C. Mello Professor in the H. Milton Stewart School of Industrial and Systems Engineering at the Georgia Institute of Technology. Her research record is quite diverse, from mathematical statistics to modeling to data analysis to statistical learning, with recent contributions on drawing principled inferences on healthcare delivery and health policy. She has also been involved in broad impact research activities; the most noteworthy is the leadership of the Health Analytics initiative (http://www.healthanalytics.gatech.edu). This is a collaborative effort anchored in partnership with a varied network of clinicians, healthcare providers, and public health entities. To date, she has published more than 60 journal articles, and a collaborative (with Dr. William B. Rouse) book titled Understanding and Managing the Complexity of Healthcare published by MIT Press and single-authored book titled Healthcare System Access: Measurement, Inference and Intervention published by Wiley. She is the editor for physical sciences, engineering, and the environment for the Annals of Applied Statistics Journal. She has reviewed for multiple funding agencies and she has served in multiple workshops and meetings organized by the National Academies.

This seminar series is presented by the U-M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi-disciplinary, systems-engineering approach. For the Zoom link and password and to be added to the weekly e-mail for the series, please RSVP. For additional questions, contact CHEPSseminar@umich.edu. Photographs and video taken at this event may be used to promote CHEPS, College of Engineering, and the University.

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Lecture / Discussion Wed, 01 Dec 2021 11:54:43 -0500 2021-12-06T16:30:00-05:00 2021-12-06T17:30:00-05:00 Industrial and Operations Engineering Building Center for Healthcare Engineering & Patient Safety (CHEPS) Lecture / Discussion Nicoleta Serban, Ph.D.
Getting Started with Slack (December 7, 2021 12:00pm) https://events.umich.edu/event/85915 85915-21665274@events.umich.edu Event Begins: Tuesday, December 7, 2021 12:00pm
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

Canvas Workshop | Level: Beginner

Slack at U-M is a collaboration tool that enhances workgroup communications. It provides a searchable platform for individuals and groups to chat in real-time, share content, and keep conversations organized and accessible from anywhere, anytime. U-M Slack accounts are available to all active faculty, staff, students, and Type one sponsored affiliates on the Ann Arbor, Dearborn, and Flint campuses and Michigan Medicine.

WORKSHOP AGENDA
- Overview of Slack at U-M
- Getting started with Slack (demo)
- Slack for Teaching (demo)
- Q&A Opportunity

The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Zoom join URL for all workshops: https://umich.zoom.us/j/96810579762

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Workshop / Seminar Fri, 03 Dec 2021 17:00:19 -0500 2021-12-07T12:00:00-05:00 2021-12-07T13:30:00-05:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar Getting Started with Slack
LHS Collaboratory (December 7, 2021 12:30pm) https://events.umich.edu/event/88230 88230-21651558@events.umich.edu Event Begins: Tuesday, December 7, 2021 12:30pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Julia Adler-Milstein, PhD
Professor of Medicine and Director of the Center for Clinical Informatics and Improvement Research (CLIIR)
University of California San Francisco

Interoperability is considered a key capability of a high-performing healthcare system and has been a top policy priority for more than a decade. Implementing interoperability is, however, a complex undertaking – requiring stakeholder coordination that tackles incentives, governance, technology, standards, and more. In this talk, Dr. Adler-Milstein will describe current approaches to interoperability and where we stand with respect to current levels of national adoption. She will then discuss the implications for Learning Health System efforts at different levels of scale.

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Livestream / Virtual Wed, 13 Oct 2021 13:59:31 -0400 2021-12-07T12:30:00-05:00 2021-12-07T14:00:00-05:00 Off Campus Location Department of Learning Health Sciences Livestream / Virtual Collaboratory logo
Statistics Department Seminar Series: Michael Law, Ph.D. Candidate, Department of Statistics, University of Michigan. (December 7, 2021 4:00pm) https://events.umich.edu/event/89208 89208-21661122@events.umich.edu Event Begins: Tuesday, December 7, 2021 4:00pm
Location: West Hall
Organized By: Department of Statistics

To be announced

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Workshop / Seminar Fri, 12 Nov 2021 16:38:25 -0500 2021-12-07T16:00:00-05:00 2021-12-07T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar West Hall
ISR-Zwerdling Seminar in Labor Economics: (December 8, 2021 2:30pm) https://events.umich.edu/event/89619 89619-21664567@events.umich.edu Event Begins: Wednesday, December 8, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Details to come.

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Workshop / Seminar Tue, 30 Nov 2021 13:26:47 -0500 2021-12-08T14:30:00-05:00 2021-12-08T15:50:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
MIPSE Seminar | Dynamics of Low Temperature Magnetized Plasmas: Self-Organization and Anomalous Electron Transport (December 8, 2021 3:30pm) https://events.umich.edu/event/86298 86298-21632606@events.umich.edu Event Begins: Wednesday, December 8, 2021 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Low-temperature magnetized plasmas are found in many systems, including plasma processing, space weather, and spacecraft propulsion. Two phenomena that are poorly understood in cross-electric and magnetic field plasma sources, such as magnetrons and Hall effect thrusters, are: (i) self-organized structures and (ii) anomalous electron transport across the magnetic field lines. In this talk, I will present the development of physics-based modeling, including fluid moment models and high-fidelity kinetic models, to address these processes. The fluid moment model coupled with improved boundary condition treatments is applied to low-temperature magnetized plasmas. The particle-based kinetic models are used to investigate multidimensional plasma turbulence initiated by a combination of kinetic instabilities in cross-field configurations. I will also introduce data-driven modeling using optimization and state estimation techniques applied to dynamical plasma systems.

About the Speaker:
Ken Hara is an Assistant Professor of Aeronautics and Astronautics at Stanford University. He received his Ph.D. in Aerospace Engineering and Graduate Certificate in Plasma Science and Engineering from the University of Michigan in 2015, and B.S. and M.S. in Aeronautics and Astronautics from the University of Tokyo in 2008 and 2010, respectively. He was a Visiting Research Physicist at Princeton Plasma Physics Laboratory as a Japan Society for the Promotion of Science Postdoctoral Fellow. He is a recipient of several awards, including the Air Force Young Investigator Program Award, the Department of Energy Early Career Award, and the Office of Naval Research Young Investigator Program Award.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Fri, 03 Sep 2021 11:49:26 -0400 2021-12-08T15:30:00-05:00 2021-12-08T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Ken Hara
Econometrics: Optimal Multi-Dimensional Mechanisms. (December 9, 2021 9:00am) https://events.umich.edu/event/89883 89883-21666278@events.umich.edu Event Begins: Thursday, December 9, 2021 9:00am
Location: Off Campus Location
Organized By: Department of Economics

Abstract: We characterize the properties of optimal selling mechanisms for the multiple-good auction and monopoly problems. In particular, for the uniform distribution of agent types, we show that the participation region is the same for auction and monopoly problems. We also compute the allocation in the optimal selling mechanism in the auction setting. Analytically, we derive the optimal selling mechanism for several other examples of the monopolistic screening model.

* To join the seminar, please contact at econ.events@umich.edu

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Workshop / Seminar Wed, 08 Dec 2021 09:13:26 -0500 2021-12-09T09:00:00-05:00 2021-12-09T10:20:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
Econometrics: Existence and Uniqueness in Matching Function Equilibria with Full Assignment (December 9, 2021 2:30pm) https://events.umich.edu/event/89548 89548-21664068@events.umich.edu Event Begins: Thursday, December 9, 2021 2:30pm
Location: Off Campus Location
Organized By: Department of Economics

Abstract:
We propose novel results for the existence of a competitive equilibrium with gross substitutes, and apply them to a class of matching problems with general transfers and without allowing for unassigned agents. An algorithm is provided. Several applications are reviewed.

*To join the seminar, please contact: econometrics-seminar-requests@umich.edu

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Workshop / Seminar Mon, 06 Dec 2021 11:13:45 -0500 2021-12-09T14:30:00-05:00 2021-12-09T15:30:00-05:00 Off Campus Location Department of Economics Workshop / Seminar econ umich
ISR-Zwerdling Seminar in Labor Economics: Increasing the Demand for Workers with a Criminal Record (joint with Zoe Cullen and Will Dobbie) (December 10, 2021 10:00am) https://events.umich.edu/event/89620 89620-21664568@events.umich.edu Event Begins: Friday, December 10, 2021 10:00am
Location: Lorch Hall
Organized By: Department of Economics

Abstract:
State and local policies increasingly restrict employers' access to criminal records, but without addressing the underlying reasons that employers may conduct criminal background checks. Employers may thus still want to ask about a job applicant's criminal record later in the hiring process or make inaccurate judgments based on an applicant's demographic characteristics. In this paper, we use a field experiment conducted in partnership with a nationwide staffing platform to test policies that more directly address the reasons that employers may conduct criminal background checks. The experiment asked hiring managers at nearly a thousand U.S. businesses to make actual hiring decisions under different randomized conditions. We find that 39% of businesses in our sample are willing to work with individuals with a criminal record at baseline, which rises to over 50% when businesses are offered crime and safety insurance, a single performance review, a background check covering just the past year, or objective information on the productivity of these individuals. Wage subsidies can achieve similar increases but at a substantially higher cost. Based on our findings, the staffing platform relaxed the criminal background check requirement and offered crime and safety insurance to interested businesses.

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Workshop / Seminar Thu, 02 Dec 2021 10:07:33 -0500 2021-12-10T10:00:00-05:00 2021-12-10T11:20:00-05:00 Lorch Hall Department of Economics Workshop / Seminar econ umich
Statistics Department Seminar Series: Weijing Tang, Ph.D. Candidate, Department of Statistics, University of Michigan. (December 10, 2021 10:00am) https://events.umich.edu/event/84427 84427-21623929@events.umich.edu Event Begins: Friday, December 10, 2021 10:00am
Location: West Hall
Organized By: Department of Statistics

To be announced

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Workshop / Seminar Fri, 12 Nov 2021 16:36:02 -0500 2021-12-10T10:00:00-05:00 2021-12-10T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar West Hall
MCDB Seminar> Flattening the Curve: Mechanosensitive Ion Channels in Plant Cell and Developmental Biology (December 10, 2021 12:00pm) https://events.umich.edu/event/85325 85325-21626228@events.umich.edu Event Begins: Friday, December 10, 2021 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Host: Erik Nielsen

* Note the new date for this event.

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Workshop / Seminar Fri, 29 Oct 2021 10:45:15 -0400 2021-12-10T12:00:00-05:00 2021-12-10T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Yellow MCDB initials and cartoon of microscope on blue
TBA (December 10, 2021 12:00pm) https://events.umich.edu/event/84691 84691-21624431@events.umich.edu Event Begins: Friday, December 10, 2021 12:00pm
Location:
Organized By: LSA Biophysics

TBA

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Workshop / Seminar Wed, 21 Jul 2021 14:51:46 -0400 2021-12-10T12:00:00-05:00 2021-12-10T13:00:00-05:00 LSA Biophysics Workshop / Seminar
M-LEEaD Fall Seminar: The Multifaceted Challenges with Microplastics and Nanoplastics (December 10, 2021 2:00pm) https://events.umich.edu/event/89047 89047-21660330@events.umich.edu Event Begins: Friday, December 10, 2021 2:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

It is all around us; micro-and nanoplastics (MNPs) are ubiquitous in the environment and are of increasing global concern. Join this M-LEEaD seminar with our Guest Speaker Dr. Elvis Genbo Xu from the University of Southern Denmark as he details the multifaceted challenges in understanding the environmental and biological fates of these small plastic particles. Meaningful ecological and human health risk assessments of MNP are only possible when we have comprehensive data around their environmental behavior, exposure levels, and toxic effects. Dr. Xu will share his recent findings on the environmental occurrence, exposures, biological effects, and toxicity mechanisms of MNPs.

About the Presenter: Dr. Elvis Genbo Xu is a tenure-track Assistant Professor of Environmental Toxicology and Sapere Aude Research Leader at the University of Southern Denmark. Xu’s research combines state-of-the-art techniques from toxicology, aquatic biology, and omics to understand the impacts of emerging pollutants. His findings of micro-and nanoplastics are featured by Nature, Science, and 200+ global media. He has secured national and international grants of over 1.3 million Euro, and published 70+ peer-reviewed articles in Acc Chem Res, PNAS, ES&T, ES&T Lett, ES Nano, J Hazard Mater, etc., with 3 ESI Highly Cited Papers and 1 Hot Paper. He is also an editorial board member of Environ Syst Res, Eco-Environ Health, J Hazard Mater, and Managing Guest Editor of Environ Inter.

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Lecture / Discussion Mon, 08 Nov 2021 14:18:20 -0500 2021-12-10T14:00:00-05:00 2021-12-10T15:00:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Image showing event title and depiction of a fish swimming with plastic
M-LEEaD Virtual Meet and Greet with Elvis Genbo Xu, PhD, University of Southern Denmark (December 10, 2021 3:00pm) https://events.umich.edu/event/89046 89046-21660328@events.umich.edu Event Begins: Friday, December 10, 2021 3:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Join U of M School of Public Health Research Assistant Professor Sean Harris, PhD, as he hosts M-LEEaD’s virtual meet and greet with, Elvis Genbo Xu, PhD, University of Southern Denmark following his fall seminar. Questions on Dr. Xu’s research, including follow up from his presentation “The Multifaceted Challenges with Microplastics and Nanoplastics”, are encouraged.
About the Presenter: Dr. Elvis Genbo Xu is a tenure-track Assistant Professor of Environmental Toxicology and Sapere Aude Research Leader at the University of Southern Denmark. Xu’s research combines state-of-the-art techniques from toxicology, aquatic biology, and omics to understand the impacts of emerging pollutants. His findings of micro-and nanoplastics are featured by Nature, Science, and 200+ global media. He has secured national and international grants of over 1.3 million Euro, and published 70+ peer-reviewed articles in Acc Chem Res, PNAS, ES&T, ES&T Lett, ES Nano, J Hazard Mater, etc., with 3 ESI Highly Cited Papers and 1 Hot Paper. He is also an editorial board member of Environ Syst Res, Eco-Environ Health, J Hazard Mater, and Managing Guest Editor of Environ Inter.

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Lecture / Discussion Mon, 08 Nov 2021 14:14:39 -0500 2021-12-10T15:00:00-05:00 2021-12-10T15:45:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Image showing Dr. Xu from the University of Southern Denmark
Issue Digital Credentials in your Course with Badgr (December 13, 2021 12:00pm) https://events.umich.edu/event/89736 89736-21665282@events.umich.edu Event Begins: Monday, December 13, 2021 12:00pm
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

Canvas Workshop | Level: Beginner

WORKSHOP TOPICS
- What is digital credentialing and competency-based learning?
- Learn how to award badges in your Canvas Course based on the learning objectives.
- Learn how badge earners can share their accomplishment on social media


The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Zoom join URL for all workshops: https://umich.zoom.us/j/96810579762

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Workshop / Seminar Fri, 03 Dec 2021 17:42:54 -0500 2021-12-13T12:00:00-05:00 2021-12-13T13:30:00-05:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar Issue Digital Credentials in your Course with Badgr
Statistics Department Seminar Series: Ian Laga, PhD Candidate, Department of Statistics, Penn State University (January 4, 2022 4:00pm) https://events.umich.edu/event/90155 90155-21668489@events.umich.edu Event Begins: Tuesday, January 4, 2022 4:00pm
Location: West Hall
Organized By: Department of Statistics

Abstract: Key populations are populations that due to higher-risk behaviors, are more likely to live with and transmit infectious diseases like HIV. These populations include female sex workers, men who have sex with men, and drug users. In order to implement efficient HIV and infectious disease prevention programs, organizations need to understand both how large these key populations are and where they live. Aggregated relational data (ARD), formed from "How many X's do you know?" questions, is a powerful tool for learning important network characters with incomplete network data. Compared to traditional survey methods, ARD is attractive as it does not require a sample from the target population and does not ask respondents to self-reveal their own status. This is helpful for studying key populations who may be hesitant to reveal their status. The Kiev International Institute of Sociology (KIIS) collected ARD to estimate the size of HIV-related subpopulations in Ukraine. To analyze this data, we propose a new ARD model which incorporates respondent and subpopulation covariates in a regression framework and adds a correlation structure to the responses. The resulting size estimates of those most-at-risk of HIV infection can improve the HIV response efficiency in Ukraine. Additionally, the proposed model allows us to better understand two network features: 1. What characteristics affect who respondents know, and 2. How is knowing someone from one group related to knowing people from other groups. These features can allow researchers to better recruit marginalized individuals into the prevention and treatment programs.

https://ilaga.github.io/

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Workshop / Seminar Tue, 21 Dec 2021 07:31:05 -0500 2022-01-04T16:00:00-05:00 2022-01-04T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Ian Laga
Statistics Department Seminar Series: Nabarun Deb, PhD Candidate, Department of Statistics, Columbia University (January 7, 2022 10:00am) https://events.umich.edu/event/90156 90156-21668490@events.umich.edu Event Begins: Friday, January 7, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: In recent years, the problem of optimal transport (see e.g., Villani (2003)) has received significant attention in statistics and machine learning due to its powerful geometric properties. In this talk, we introduce the optimal transport problem and present concrete applications of this theory in statistics. In particular, we will propose a general framework for distribution-free nonparametric testing in multi-dimensions, based on a notion of "multivariate ranks" defined using the theory of optimal transport. We demonstrate the applicability of this approach by constructing exactly distribution-free tests for two classical nonparametric problems: (i) testing for the equality of two multivariate distributions, and (ii) testing for mutual independence between two random vectors. We investigate the consistency and asymptotic distributions of these tests, both under the null and local contiguous alternatives. We further study their local power and asymptotic (Pitman) efficiency, and show that a subclass of these tests achieve attractive efficiency lower bounds that mimic the remarkable efficiency results of Hodges
and Lehmann (1956) and Chernoff and Savage (1958). To the best of our knowledge, these are the first collection of multivariate exactly distribution-free tests that provably achieve such attractive efficiency lower bounds.

Finally, we also study the rates of convergence of the estimated optimal transport maps, which are of pivotal importance in generative modeling, domain adaptation, etc. We will show that the natural plugin estimators for these maps achieve minimax optimal rates of convergence without any tuning parameters.

https://nabarund.github.io/

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Workshop / Seminar Tue, 21 Dec 2021 08:31:03 -0500 2022-01-07T10:00:00-05:00 2022-01-07T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Nabarun Deb
Hybrid self-assembled nanomaterials from proteins, peptides, and DNA (January 7, 2022 12:00pm) https://events.umich.edu/event/84772 84772-21624927@events.umich.edu Event Begins: Friday, January 7, 2022 12:00pm
Location: Chemistry Dow Lab
Organized By: LSA Biophysics

The ability to design materials that mimic the complexity and functionality of biological systems is a long standing goal of nanotechnology, with applications in medicine, energy, and fundamental science. Biological molecules such as proteins, peptides, and DNA possess a rich palette of self-assembly motifs and chemical functional diversity, and are attractive building blocks for the synthesis of such nanomaterials. In this talk, we will describe research in creating hybrid materials that incorporate proteins and peptides with DNA nanotechnology to create cages, nanofibers, and 3D crystals with a high degree of programmability and nanoscale resolution. Key to these endeavors will be (bio)molecular design, organic chemistry for linking components in a site-specific fashion, and the tuning of multiple self-assembly "modes" to create hybrid structures. Although the talk will focus on the fundamental chemistry and self-assembly of these systems, we will also discuss potential applications in areas such as targeted cargo delivery, biomaterials for regenerative medicine, biophysical devices, and synthesis of virus- and antibody-mimetic nanostructures.

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Workshop / Seminar Mon, 03 Jan 2022 09:09:21 -0500 2022-01-07T12:00:00-05:00 2022-01-07T13:00:00-05:00 Chemistry Dow Lab LSA Biophysics Workshop / Seminar Chemistry Dow Lab
New Quizzes - Join the future of quizzing in Canvas! (January 10, 2022 3:00pm) https://events.umich.edu/event/89734 89734-21665284@events.umich.edu Event Begins: Monday, January 10, 2022 3:00pm
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

Canvas Workshop | Level: Beginner

Instructure has set a timeline for New Quizzes to become the native quizzing engine, within U-M’s Canvas LMS instance, and retire Classic Quizzes by summer 2023. Beginning in July 2022 Classic Quizzes will no longer allow users to create or edit quizzes. This is a significant change and we want to keep U-M faculty and staff informed as we prepare for the transition from Classic Quizzes to New Quizzes, to ensure a seamless migration experience.

WORKSHOP TOPICS
- Overview of the Migration from Classic Quizzes to New Quizzes
- Setup of Quizzes
- Quiz options
- Previewing Quizzes
- Moderating Quizzes

The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Zoom join URL for all workshops: https://umich.zoom.us/j/96810579762

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The New Quizzes Workshop has been rescheduled from the previously scheduled date of January 6. If the new date listed does not meet your needs, please visit the on-demand recording of this workshop. https://www.mivideo.it.umich.edu/playlist/dedicated/137537371/1_zj8epx1q/1_mdczk1q4

We apologize for any inconvenience this change may cause.

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Workshop / Seminar Wed, 05 Jan 2022 09:00:29 -0500 2022-01-10T15:00:00-05:00 2022-01-10T16:30:00-05:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar New Quizzes - Join the future of quizzing in Canvas!
Freshen Up Your Canvas Assignments (January 11, 2022 12:00pm) https://events.umich.edu/event/90407 90407-21670712@events.umich.edu Event Begins: Tuesday, January 11, 2022 12:00pm
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

Canvas Workshop | Level: Beginner

WORKSHOP TOPICS
Consider two new ways to set up assignments in Canvas:
- New Google Assignments: Streamline the distribution of assignment templates with Google docs and provide instant feedback within student submissions
- Student Annotation assignment type: Allow students to directly annotate on uploads and submit as a Canvas assignment

The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Zoom join URL for all workshops: https://umich.zoom.us/j/96810579762

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Workshop / Seminar Mon, 10 Jan 2022 15:22:53 -0500 2022-01-11T12:00:00-05:00 2022-01-11T13:30:00-05:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar Freshen Up Your Canvas Assignments
Statistics Department Seminar Series: Xiaowu Dai, Postdoctoral Research Fellow, Department of Economics, University of California, Berkeley (January 11, 2022 4:00pm) https://events.umich.edu/event/90158 90158-21668491@events.umich.edu Event Begins: Tuesday, January 11, 2022 4:00pm
Location: West Hall
Organized By: Department of Statistics

Abstract: We study the problem of decision-making in the setting of a scarcity of shared resources when the preferences of agents are unknown a priori and must be learned from data. Taking the two-sided matching market as a running example, we focus on the decentralized setting, where agents do not share their learned preferences with a central authority. Our approach is based on the representation of preferences in a reproducing kernel Hilbert space, and a learning algorithm for preferences that accounts for uncertainty due to the competition among the agents in the market. Under regularity conditions, we show that our estimator of preferences converges at a minimax optimal rate. Given this result, we derive optimal strategies that maximize agents' expected payoffs and we calibrate the uncertain state by taking opportunity costs into account. We also derive an incentive-compatibility property and show that the outcome from the learned strategies has a stability property. Finally, we prove a fairness property that asserts that there exists no justified envy according to the learned strategies.

This is a joint work with Michael I. Jordan.

https://www.xiaowudai.org/

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Workshop / Seminar Tue, 21 Dec 2021 07:42:19 -0500 2022-01-11T16:00:00-05:00 2022-01-11T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Xiaowu Dai
Spark Engagement with Adobe Creative Cloud Express! (January 13, 2022 12:00pm) https://events.umich.edu/event/89735 89735-21670704@events.umich.edu Event Begins: Thursday, January 13, 2022 12:00pm
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

Canvas Workshop | Level: Beginner

WORKSHOP TOPICS
- Explore Adobe Creative Cloud Express, an integrated suite of media creation applications for mobile and web. Users can create Creative Cloud Express Web Pages (presentations), Creative Cloud Express Posts, and Creative Cloud Express Videos
- Learn the 3 types of Student Interactions (student-content, student-student, student-instructor) and how you can use Adobe Creative Cloud Express with these interactions
- Review of the 4 Principles of Engagement and how to apply these principles with Adobe Creative Cloud Express
- Learn strategies to keep students engaged online
Create your own engagement plan

The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Zoom join URL for all workshops: https://umich.zoom.us/j/96810579762
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NOTE: The Adobe Creative Cloud Express Workshop has been rescheduled to Thursday, January 13 at noon from the previous date of January 6. If this new date does not meet your needs, please visit the on-demand recording of this workshop.
https://www.mivideo.it.umich.edu/playlist/dedicated/137537371/1_zj8epx1q/1_4x8oli6e

We apologize for any inconvenience this change may cause.

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Workshop / Seminar Wed, 05 Jan 2022 09:03:07 -0500 2022-01-13T12:00:00-05:00 2022-01-13T13:30:00-05:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar Spark Engagement with Adobe Creative Cloud Express!
A Truly Subject-Specific, Shared Model of the Human Tricuspid Valve (January 13, 2022 3:30pm) https://events.umich.edu/event/90763 90763-21673517@events.umich.edu Event Begins: Thursday, January 13, 2022 3:30pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Abstract: Computer simulations have become critical elements of the medical device design and regulatory approval process. Naturally, the predictability and therefore value of such simulations depends highly on their accuracy. Especially for the design of heart valve replacements and repair technologies computer simulations have become a critical tool. While much progress has been made in modeling the aortic valve and the mitral valve, much less effort has been spent on modeling the tricuspid valve. The reasons are multi-fold, but include the general neglect of the valve as well as the high complexity of the valve in comparison to the three other valves. In our most recent work, we are beginning to fulfill this gap. Specifically, our objective is to develop, validate, and then publicly provide a truly subject-specific, shared model of the human tricuspid valve. To this end, we combine multi imaging-modality based measurements in beating human hearts that have been prepared in an organ preservation system, with in-vitro measurements of heart valve geometric, structural, and mechanical properties. Once built, we conduct finite element simulations with this valve and validate dynamic simulations throughout the cardiac cycle against in-situ measurements. Finally, we show case our model by first mimicking a diseased valve, which we then repair using a surgical and an interventional approach.

Bio: Dr. Rausch is an assistant professor at the University of Texas at Austin where he directs the soft tissue biomechanics laboratory. His laboratory's objective is to use complimentary imaging modalities, mechanical testing, and numerical methods to understand and predict soft tissue disease. The specific problems he studies include pressure ulcers, right heart heart failure, tricuspid valve regurgitation, and thrombotic disease. Check out his work on www.manuelrausch.com and follow him on Twitter under @ManuelKRausch1.

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Workshop / Seminar Mon, 10 Jan 2022 16:14:23 -0500 2022-01-13T15:30:00-05:00 2022-01-13T16:30:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME Seminar
Statistics Department Seminar Series: Colin Fogarty, Assistant Professor, Department of Operations Research and Statistics, Sloan School of Management, Massachusetts Institute of Technology (January 14, 2022 10:00am) https://events.umich.edu/event/90159 90159-21668492@events.umich.edu Event Begins: Friday, January 14, 2022 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Competing approaches to inference in randomized experiments differ primarily in (1) which notion of ``no treatment effect’’ being tested; and (2) whether or not a superpopulation model is posited for the potential outcomes. Recommended hypothesis tests in a given paradigm may be invalid even asymptotically when applied in other frameworks, creating the risk of misinterpretation by practitioners when a given method is deployed. For a large class of test statistics common in practice, we develop a general framework for ensuring validity across competing modes of inference. To do this, we employ permutation tests based upon prepivoted test statistics, wherein a test statistic is first transformed by a suitably constructed cumulative distribution function and its permutation distribution is then enumerated. In essence, the approach uses the permutation distribution of a p-value for a large-sample test known to be valid under the null hypothesis of no average treatment effect as a reference distribution. The framework readily accommodates regression-adjusted estimators of average treatment effects, and the corresponding tests are never less powerful asymptotically than a test based upon the unadjusted estimator and maintain asymptotic validity even if the regression model is misspecified. The tests retain finite-sample exactness under stricter definitions of no treatment effect such as Fisher’s sharp null by virtue of being permutation tests, and validity across different superpopulation models can be ensured through the choice of the estimated CDF used when prepivoting.

http://www.mit.edu/~cfogarty/

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Workshop / Seminar Thu, 06 Jan 2022 15:53:53 -0500 2022-01-14T10:00:00-05:00 2022-01-14T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Colin Fogarty
Advancing Climate Justice & Environmental Health: people-centered approaches to transformational research (January 18, 2022 12:00pm) https://events.umich.edu/event/90764 90764-21673518@events.umich.edu Event Begins: Tuesday, January 18, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

REGISTRATION REQUIRED
https://umich.zoom.us/webinar/register/WN_qa4rv9J3SZehApoPqRPIVw
A life-long learner and advocate, Dr. Jalonne L. White-Newsome founded Empowering a Green Environment and Economy, LLC, a strategic consulting firm, with the mission of transforming communities through the development of people-centered solutions. She serves a diverse set of clients with forward-thinking and intersectional approaches to tackle issues such as climate change, public health, environmental injustice, and advancing racial equity.

Dr. White-Newsome ha has multi-sector experience having worked in environmental philanthropy, state government, non-profit, grassroots, academia and private industry. Most notably, she created and implemented the transformational Climate Resilient and Equitable Water Systems (CREWS) Initiative at the Kresge Foundation as a Senior Program Officer; she was the first Director of WE ACT for Environmental Justice’s federal policy office in Washington, DC; and, her doctoral research illuminated the impact of climate change & extreme heat on the low-income, elderly in Detroit, and is still referenced to drive public health interventions.

A native of Detroit, Jalonne earned a Ph.D. in environmental health sciences from the University of Michigan School of Public Health, a master’s degree in environmental engineering from Southern Methodist University, a bachelor’s degree in chemical engineering from Northwestern University, and her certificate in Diversity and Inclusion from Cornell University.

Jalonne serves on multiple national and local academic, non-profit and for-profit Boards. She is a Lecturer at The George Washington University Milken Institute School of Public Health, a lifetime member of Delta Sigma Theta Sorority, Inc., and the proud mom of Arielle and Jeannelyn.

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Lecture / Discussion Mon, 10 Jan 2022 16:24:08 -0500 2022-01-18T12:00:00-05:00 2022-01-18T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Jan 18 Advancing Climate Justice & Environmental Health
LHS Collaboratory (January 18, 2022 12:00pm) https://events.umich.edu/event/89940 89940-21666535@events.umich.edu Event Begins: Tuesday, January 18, 2022 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

This presentation will explore how Big Data Science and Informatics research can overcome deficiencies within the electronic health record and optimize real world data collection. We will discuss examples of how standardized nomenclature integrated into clinical workflow can enable statistical AI methods to advance clinical decision support and improve outcome models. Our successes in radiation oncology come from single multi-institutional, multi-national and multi-professional society collaboration.

Presenters:
Charles Mayo, PhD
Professor
Director of Radiation Oncology Informatics and Analytics
Department of Radiation Oncology
University of Michigan Medical School

Michelle Mierzwa, MD
Associate Professor
Associate Chair of Clinical Research
Co-Chair of Head and Neck Clinical Trials
Department of Radiation Oncology
University of Michigan Medical School

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Lecture / Discussion Tue, 11 Jan 2022 15:56:37 -0500 2022-01-18T12:00:00-05:00 2022-01-18T13:30:00-05:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Collaboratory logo
"Lessons learned from a tumor suppressor gene and its effects in stratified epithelia" (January 18, 2022 4:00pm) https://events.umich.edu/event/90539 90539-21671506@events.umich.edu Event Begins: Tuesday, January 18, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following seminar with speaker Cristiane Squarize DDS, MS, PhD. Dr. Squarize works at the Department of Periodontics and Oral Medicine focusing on the Division of Oral Pathology, Radiology and Medicine at the University of Michigan School of Dentistry.

Her talk is entitled, "Lessons learned from a tumor suppressor gene and its effects in stratified epithelia".

Faculty Host: Linda Samuelson, PhD, Molecular & Integrative Physiology

For more info email:Organogenesis@umich.edu

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Lecture / Discussion Thu, 06 Jan 2022 10:32:51 -0500 2022-01-18T16:00:00-05:00 2022-01-18T17:00:00-05:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion Flyer for the Event
Statistics Department Seminar Series: Marie-Christine Düker, Postdoctoral Research Fellow, Department of Statistics and Data Science, Cornell University (January 18, 2022 4:00pm) https://events.umich.edu/event/90161 90161-21668493@events.umich.edu Event Begins: Tuesday, January 18, 2022 4:00pm
Location: West Hall
Organized By: Department of Statistics

Abstract: The long-run variance matrix and its inverse, the so-called precision matrix, give, respectively, information about correlations and partial correlations between dependent component series of multivariate time series around zero frequency. This talk will present non-asymptotic theory for estimation of the long-run variance and precision matrices for high-dimensional time series under general assumptions on the dependence structure including long-range dependence. The presented results for thresholding and penalizing versions of the classical local Whittle estimator ensure consistent estimation in a possibly high-dimensional regime. The highlight of this talk is a concentration inequality of the local Whittle estimator for the long-run variance matrix around the true model parameters. In particular, it handles simultaneously the estimation of the memory parameters which enter the underlying model. A simulation study and an application will also be presented. 

https://mariedueker.github.io/

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Workshop / Seminar Fri, 07 Jan 2022 16:35:50 -0500 2022-01-18T16:00:00-05:00 2022-01-18T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Marie Duker
Statistics Department Seminar Series: Yongyi Guo, PhD Candidate, Department of Operations Research & Financial Engineering, Princeton University (January 21, 2022 10:00am) https://events.umich.edu/event/90162 90162-21668495@events.umich.edu Event Begins: Friday, January 21, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Dynamic pricing is one of the most common examples of online decision problems. With the development of e-commerce and the massive real-time data in online platforms today, feature-based pricing has become increasingly important. Semi-parametric feedback structure is a natural formulation in such problems, and benefits from tools from non-parametric statistical estimation.

In this work, we study feature-based pricing with semi-parametric feedback structure. We propose a dynamic learning and decision algorithm that makes use of the classical idea of the tradeoff between exploration (statistical estimation) and exploitation (reward optimization). Under mild conditions, our proposed algorithm achieves near-optimal regret in terms of dependence on the time horizon. This result offers a new perspective on combining statistical learning and decision-making in the online decision context.

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Workshop / Seminar Mon, 10 Jan 2022 13:53:43 -0500 2022-01-21T10:00:00-05:00 2022-01-21T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar West Hall
Statistics Department Seminar Series: Koulik Khamaru, PhD Candidate, Department of Statistics, University Of California, Berkeley (January 25, 2022 4:00pm) https://events.umich.edu/event/90163 90163-21668497@events.umich.edu Event Begins: Tuesday, January 25, 2022 4:00pm
Location: West Hall
Organized By: Department of Statistics

Abstract: In recent years, there has been tremendous progress in the field of reinforcement learning (RL), especially on the empirical side. But it is fair to say that there is a considerable gap between theory and practice: many RL methods behave far better than existing worst-case theory would suggest, and often they work in settings where the current worst-case guarantees are completely prohibitive. In this talk, we will discuss why worst-case guarantees can severely overestimate the difficulty of reinforcement learning problems in presence of favorable structure. This motivates us to consider an instance-dependent difficulty measure that is responsive to the problem structure. Next, we discuss how we can construct estimators that adapt to this instance-dependent difficulty. We show that for problems with favorable structures our proposed estimators and associated confidence regions are significantly better than those obtained from the worst-case theory. Finally, we show that the techniques that we developed for constructing instance-dependent estimators are not specific to RL problems, and they can be applied to a broad class of other problems.

https://www.stat.berkeley.edu/~koulik/

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Workshop / Seminar Tue, 18 Jan 2022 09:59:48 -0500 2022-01-25T16:00:00-05:00 2022-01-25T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Koulik Khamaru
MIPSE Seminar | A Cocktail of Active Ingredients - Benefits and Challenges for Plasma Medicine (January 26, 2022 3:30pm) https://events.umich.edu/event/90464 90464-21671090@events.umich.edu Event Begins: Wednesday, January 26, 2022 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Low-temperature plasmas in or in contact with air produce a variety of reactive oxygen and nitrogen species (RONS) – some being the same molecules that the human body generates for signaling or antimicrobial effects. Plasma treatment of eukaryotic cells can therefore cause similar effects as an innate immune system oxidative burst. Plasma exposure can mimic an immune response to tissue damage which could initiate a natural healing response. Utilizing plasma-generated RONS for plasma-aided wound healing or plasma oncology is a promising alternative to conventional treatments. Yet, the mechanisms of action and the delivery of RONS to the target are currently still under investigation. In this talk we will explore the cocktail of active ingredients produced by plasmas; the generation and transport of the reactive species O and OH from the gas phase through a liquid to a biological sample and investigate the role that the biological sample plays as part of the reaction pathway. Using the model biological sample cysteine, the results indicate that OH/H2O2-dominated chemistry is similar to that found in redox biology, whereas modifications caused by O-dominated chemistry differ significantly. Atomic oxygen is unknown in nature whereas OH and H2O2 are well known and produced by organisms. The cocktail of RONS and variety plasma sources make it difficult generalize the impact of plasma on cells. However, the tunability of plasma and the ability to tailor RONS to desired outcomes provides a promising tool for the healing of wounds and new strategies in cancer treatment.

About the Speaker:
Katharina Stapelmann is an assistant professor of nuclear engineering at North Carolina State University. She received her Ph.D. in electrical engineering from Ruhr University Bochum, Germany, in 2013, where she continued as postdoc (2014) and assistant professor of electrical engineering (2015-2017) before she joined NC State in 2017. Stapelmann’s research interests lie in the experimental investigation of generation and transport of reactive species for life science applications, e.g., plasma medicine and plasma agriculture. The focus of her research program is on plasma device development, plasma diagnostics, and the interaction of plasmas with biological substrates and systems. Stapelmann is Mercator Fellow (DFG), speaker of the board of trustees of the German national center of plasma medicine and serves on the International Advisory Board of the Journal Plasma Processes and Polymers. In 2021 she was identified as “Emerging Leader” by the IOP Journal of Physics D: Applied Physics.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Wed, 05 Jan 2022 09:24:21 -0500 2022-01-26T15:30:00-05:00 2022-01-26T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Katharina Stapelmann
Elasticity Imaging: From Fibrosis and Tumor Pressure to Mechanotransduction and Visualizing Primary Neuronal Activity (January 27, 2022 3:30pm) https://events.umich.edu/event/91489 91489-21680069@events.umich.edu Event Begins: Thursday, January 27, 2022 3:30pm
Location: Off Campus Location
Organized By: Biomedical Engineering

Abstract:
Only recently have we understood the importance of mechanical forces between cells to generate tissue homeostasis. This translates equally to the organ level with tissue biomechanics an excellent proxy for pathological alterations.

In this lecture we will review the current method of quantifying tissue biomechanics via MRI using mechanical shear waves elicitated at the surface of the patient, new ways to quantify non-invasively tumour pressure via non-linear mechanics, and look into mechanical changes induced by neuronal activities. Finally, we will change our position from being a passive bystander quantifying tissue mechanics to an active player altering cellular fate via shear waves.
Bio:
Professor Ralph Sinkus is a physicist with a background in high energy physics, nuclear physics and MRI. He has dual labs at King’s College London’s School of Biomedical Engineering and Imaging Sciences as well as at INSERM (University Paris Diderot, Sorbonne Paris Cité, Hôpital Bichat/Beaujon, Paris, France). After a PhD in high energy physics (DESY, Deutsches Elektronen Synchrotron, Hamburg, Germany), Professor Sinkus took a position at Philips Medical Systems Research Laboratories (Hamburg, Germany) focusing on magnetic resonance imaging (MRI) and elastography. Moving back to academia, Professor Sinkus worked for the Laboratoire Ondes et Acoustique (ESPCI) in Paris, France as a research director until accepting a chair position at King’s College London. Professor Sinkus is an expert in MRI and MR-elastography, and works with a diverse range of clinicians, biomedical engineers, physists and mathematicians for the translation of these technologies to address clinical diagnostics through imaging.
Organized by:
Dr. Brendon Baker,
Assistant Professor, Biomedical Engineering

Dr. David Nordsletten,
Associate Professor, Department of Biomedical Engineering and Cardiac Surgery

Zoom Link: https://umich.zoom.us/j/96508834308

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Workshop / Seminar Tue, 25 Jan 2022 13:56:46 -0500 2022-01-27T15:30:00-05:00 2022-01-27T16:30:00-05:00 Off Campus Location Biomedical Engineering Workshop / Seminar BME Seminar
Statistics Department Seminar Series: Zijun Gao, PhD Candidate, Department of Statistics, Stanford University (January 28, 2022 10:00am) https://events.umich.edu/event/90164 90164-21668498@events.umich.edu Event Begins: Friday, January 28, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: "Heterogeneous treatment effect models allow us to compare treatments at subgroup and individual levels, and are of increasing popularity in applications like personalized medicine, advertising, and education. In this talk, we first survey different causal estimands used in practice, which focus on estimating the difference in conditional means. We then propose DINA — the difference in natural parameters — to quantify heterogeneous treatment effect in exponential families and the Cox model. For binary outcomes and survival times, DINA is both convenient and more practical for modeling the influence of covariates on the treatment effect. Second, we introduce a meta-algorithm for DINA, which allows practitioners to use powerful off-the-shelf machine learning tools for the estimation of nuisance functions, and which is also statistically robust to errors in inaccurate nuisance function estimation. We demonstrate the efficacy of our method combined with various machine learning base-learners on simulated and real datasets."

https://zijungao.github.io/

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Workshop / Seminar Tue, 18 Jan 2022 09:53:01 -0500 2022-01-28T10:00:00-05:00 2022-01-28T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Zijun Gao
Noncoding RNA structure and recognition in stress response and immunity (January 28, 2022 12:00pm) https://events.umich.edu/event/84689 84689-21624429@events.umich.edu Event Begins: Friday, January 28, 2022 12:00pm
Location: Off Campus Location
Organized By: LSA Biophysics

The goal of our research is to gain a detailed structural and mechanistic understanding of cellular and viral noncoding RNAs (ncRNAs). Our recent work has focused on investigating how two archetypes of ncRNAs — the tRNA and the double-stranded RNA (dsRNA), as well as RNAs that mimic them, mediate cellular responses to stress, regulate HIV-1 replication, and modulate host innate immunity.

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Workshop / Seminar Wed, 12 Jan 2022 13:30:19 -0500 2022-01-28T12:00:00-05:00 2022-01-28T13:00:00-05:00 Off Campus Location LSA Biophysics Workshop / Seminar
MCDB Dissertation Defense > Investigating the proliferation-quiescence decision in tissues and in cancer cells (January 31, 2022 12:00pm) https://events.umich.edu/event/91611 91611-21681029@events.umich.edu Event Begins: Monday, January 31, 2022 12:00pm
Location: Biological Sciences Building
Organized By: Department of Molecular, Cellular, and Developmental Biology

Mentor: Laura Buttitta

Hybrid event
check the Weekly Update or email: mcdb.seminar.info@umich.edu for zoom link and password

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Workshop / Seminar Thu, 27 Jan 2022 12:44:07 -0500 2022-01-31T12:00:00-05:00 2022-01-31T13:00:00-05:00 Biological Sciences Building Department of Molecular, Cellular, and Developmental Biology Workshop / Seminar Yellow MCDB initials Microscope cartoon on blue
"Hepato-Biliary-Pancreatic Organogenesis in a Dish" (February 1, 2022 4:00pm) https://events.umich.edu/event/90540 90540-21671507@events.umich.edu Event Begins: Tuesday, February 1, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following seminar with speaker Takanori Takebe, MD, PhD. Dr. Takebe is the Chair of Organoid Medicine, member of the Center for Stem Cell and Organoid Medicine (CuSTOM), and within the Divisions of Gastroenterology, Hepatology and Nutrition and Developmental Biology at the Cincinnati Children's Hospital Medical Center.

His talk is entitled, "Hepato-Biliary-Pancreatic Organogenesis in a Dish"

Faculty Host: Idse Heemskerk, PhD, Cell and Developmental Biology

For more info, email Organogenesis@umich.edu

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Livestream / Virtual Thu, 06 Jan 2022 10:53:07 -0500 2022-02-01T16:00:00-05:00 2022-02-01T17:00:00-05:00 Off Campus Location Center for Cell Plasticity and Organ Design Livestream / Virtual Flyer for the Event
Statistics Department Seminar Series: Weibin Mo, Applied Scientist, Supply Chain Optimization and Technologies, Amazon (February 1, 2022 4:00pm) https://events.umich.edu/event/90165 90165-21668499@events.umich.edu Event Begins: Tuesday, February 1, 2022 4:00pm
Location: West Hall
Organized By: Department of Statistics

Abstract: Recent development in data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, researchers can search for the optimal individualized treatment rule (ITR) that maximizes the expected outcome. Existing methods typically require initial estimation of some nuisance models. The double robustness property that can protect from misspecification of either the treatment-free effect or the propensity score has been widely advocated. However, when model misspecification exists, a doubly robust estimate can be consistent but may suffer from downgraded efficiency. Other than potential misspecified nuisance models, most existing methods do not account for the potential problem when the variance of outcome is heterogeneous among covariates and treatment. We observe that such heteroscedasticity can greatly affect the estimation efficiency of the optimal ITR. In this presentation, we demonstrate that the consequences of misspecified treatment-free effect and heteroscedasticity can be unified as a covariate-treatment dependent variance of residuals. To improve efficiency of the estimated ITR, we propose an Efficient Learning (E-Learning) framework for finding an optimal ITR in the multi-armed treatment setting. We show that the proposed E-Learning is optimal among a regular class of semiparametric estimates that can allow treatment-free effect misspecification. In our simulation study, E-Learning demonstrates its effectiveness if one of or both misspecified treatment-free effect and heteroscedasticity exist. Our analysis of aType 2 Diabetes Mellitus observational study also suggests the improved efficiency of E-Learning.

https://sites.google.com/view/weibin-mo

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Workshop / Seminar Mon, 10 Jan 2022 13:49:42 -0500 2022-02-01T16:00:00-05:00 2022-02-01T17:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Weibin Mo
Learning Health Systems: A Pathway to Sustainable Health Improvement (February 3, 2022 12:00pm) https://events.umich.edu/event/91725 91725-21682582@events.umich.edu Event Begins: Thursday, February 3, 2022 12:00pm
Location:
Organized By: Office of Research School of Dentistry

Charles Friedman is the Josiah Macy Jr. Professor of Medical Education and Chair of the Department of Learning Health Sciences at the University of Michigan Medical School. In recent years, he has focused his academic interests and activities on the concept of Learning Health Systems, and the socio-technical infrastructure required to sustain them. He is editor-in-chief of the open-access journal Learning Health Systems and co-chair of the movement to Mobilize Computable Biomedical Knowledge.

He was recently awarded an honorary doctorate by the University of Lucerne in Switzerland for his contributions to the science of Learning Health Systems.
Prior to coming to Michigan, Friedman held executive positions at the Office of the National Coordinator for Health IT (ONC) in the U.S. Department of Health and Human Services. Immediately prior to his work in the government, Dr. Friedman was Associate Vice Chancellor for Biomedical Informatics, and Founding Director of the Center for Biomedical Informatics at the University of Pittsburgh.

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Presentation Mon, 31 Jan 2022 11:39:40 -0500 2022-02-03T12:00:00-05:00 2022-02-03T13:00:00-05:00 Office of Research School of Dentistry Presentation Charles P. Friedman, PhD
Statistics Department Seminar Series: Ziwei Zhu, Assistant Professor, Department of Statistics, University of Michigan (February 4, 2022 10:00am) https://events.umich.edu/event/90166 90166-21668500@events.umich.edu Event Begins: Friday, February 4, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: In this talk, I will present two recent works on rank-constrained least squares and distributed statistical learning respectively. The first part of the talk highlights a near optimal in-sample prediction error bound for the rank-constrained least squares estimator with no assumption on the design matrix. Lying at the heart of the proof is a covering number bound for the family of projection operators corresponding to the subspaces spanned by the design. By leveraging this complexity result, we perform a power analysis for a permutation test on the existence of a low-rank signal under the high-dimensional trace regression model. The second part of the talk proposes a new one-shot distributed learning algorithm through refitting Bootstrap samples from local models, which we refer to as ReBoot. Given that the full sample is split into m subsamples of size n, we show that ReBoot yields bias of order (1 / n ^ 2) under generalized linear models. This bias rate is sharper than that of vanilla or subsampled averaging of the local MLEs. Simulation and real data analysis both demonstrate the superior statistical accuracy of ReBoot over competing methods including Communication-efficient Surrogate Likelihood (CSL) and Federated Averaging (FedAvg).


Ziwei Zhu is an Assistant Professor at the Department of Statistics at the University of Michigan, Ann Arbor. His research interests are federated/distributed statistical learning, high-dimensional statistics, robust statistics, and missing data.

Prior to UMich, he was a research associate at the Statistical Laboratory at the University of Cambridge, hosted by Professor Richard Samworth. He obtained his Ph.D. at the Department of Operations Research and Financial Engineering (ORFE) at Princeton University, advised by Professor Jianqing Fan, and did his undergraduate study at the Special Class of Gifted Young at the University of Science and Technology of China (USTC).

His recent research focus is on best subset selection and communication-efficient statistical learning algorithms.

https://purplebamboo1993.github.io/personal_web/

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Workshop / Seminar Thu, 27 Jan 2022 11:36:25 -0500 2022-02-04T10:00:00-05:00 2022-02-04T11:00:00-05:00 West Hall Department of Statistics Workshop / Seminar Ziwei Zhu
Long-term Air Pollution and Incident Dementia in U.S. (February 8, 2022 12:00pm) https://events.umich.edu/event/91240 91240-21677512@events.umich.edu Event Begins: Tuesday, February 8, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

REGISTRATION REQUIRED
https://umich.zoom.us/webinar/register/WN_d_LFab2xTmmTjHuJsfZLmg

Liuhua Shi, ScD, is Assistant Professor of Environmental Health in the Rollins School of Public Health at Emory University.

Dr. Shi's research focuses on employing massive datasets, including satellite-retrieved high resolution exposures and health data, to investigate how climate change and air pollution influence seniors' health.

More specifically, her research is focused on:
1. application of remote sensing in environmental exposure modeling (e.g., predicting high-resolution PM2.5, ozone, NO2, and temperature);
2. estimating the health consequences of exposure to air pollution and climate change;
3. estimating the link between climate change and air quality, and the mediated health impacts;
4. estimating the joint and independent health effects of air pollutant mixtures;
5. statistical modeling, e.g., causal modeling and big data approach.

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Lecture / Discussion Wed, 19 Jan 2022 13:12:34 -0500 2022-02-08T12:00:00-05:00 2022-02-08T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Air pollution and dementia
CBSSM Seminar- Laila Gharzai, MD, LLM (February 9, 2022 2:00am) https://events.umich.edu/event/91947 91947-21684286@events.umich.edu Event Begins: Wednesday, February 9, 2022 2:00am
Location: Off Campus Location
Organized By: Center for Bioethics and Social Sciences in Medicine (CBSSM)

Financial toxicity has a substantial impact on patients undergoing cancer treatment. Strategies to mitigate this complex problem have found challenges in facing its multifaceted nature. As a postdoctoral research fellow at CBSSM, I performed a qualitative study of patients who experienced financial toxicity during cancer treatment in order to contextualize their experience within an existing framework for understanding financial toxicity. This enabled identification of a novel theme impacting the experience of financial toxicity, and led us to identify four major areas where additional work is needed to mitigate financial toxicity. This work will be placed in context of drivers and other mitigation efforts in financial toxicity.

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Lecture / Discussion Thu, 03 Feb 2022 15:42:36 -0500 2022-02-09T02:00:00-05:00 2022-02-09T15:00:00-05:00 Off Campus Location Center for Bioethics and Social Sciences in Medicine (CBSSM) Lecture / Discussion Laila Gharzai, MD Feb 9 Seminar
Brian M. Wells and Hani Zainulbhai - Using a Web Diary Survey to Measure Out-of-Home Media Consumption and Engagement (February 9, 2022 12:00pm) https://events.umich.edu/event/90980 90980-21675125@events.umich.edu Event Begins: Wednesday, February 9, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

Brian M. Wells is a Senior Data Scientist at Nielsen where he works on a variety of quantitative projects to evaluate, improve, and expand Nielsen panels. Previously he served as the Data Quality and Survey Methodology Manager for the California Health Interview Survey (CHIS) where he evaluated the need for and implemented a new data collection methodology. Brian received his PhD in Survey Methodology from the University of Michigan.

Hani Zainulbhai is a Senior Data Scientist at Nielsen and a 2018 MPSM graduate. At Nielsen, she has been involved in developing alternative recruitment methods for the TV audience measurement panel.

Using a Web Diary Survey to Measure Out-of-Home Media Consumption and Engagement

Dimensions of out-of-home (OOH) media measurement rely on human input and cannot be fully captured through passive data collection via smart devices or portable meters. To better understand OOH TV consumption, we designed a web-based diary survey to capture the various components of OOH TV consumption while trying to minimize recall bias, especially for brief, unanticipated viewings. The study consisted of two parts: a Recruitment phase and a Diary phase. During the Recruitment phase, selected panelists from a nationally representative sample completed a short survey and were asked to participate in the 7-day diary. Those who agreed were enrolled in the Diary and were asked to complete a once-daily diary, logging all their OOH activity and TV consumption. The surveys were conducted over four weeks from mid-October to mid-November 2021, with each week having an independent and representative sample covering a different 7-day period. This presentation will provide an overview of the methodology and process used to administer the Recruitment and Diary surveys, including sample design, recruitment procedures, web-based diary survey design, and participation and response rates for each survey. In addition, we will discuss the results of a questionnaire experiment exploring differences between the concepts of attention to and engagement with media. A random half-sample was assigned questions about either “attention” or “engagement” to each program viewed. Within each half-sample, we also randomly assigned each respondent to an ascending or a descending response order condition to observe if there is any primacy effect due to collection in a self-administered mode. Preliminary results show differences in the distributions for attention and engagement implying some differentiation in how respondents perceive these two measures. In addition, the direction of the response order seems to alter the response distribution for attention but not for engagement.

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Lecture / Discussion Thu, 27 Jan 2022 14:44:56 -0500 2022-02-09T12:00:00-05:00 2022-02-09T13:00:00-05:00 Off Campus Location Michigan Program in Survey and Data Science Lecture / Discussion Brian M. Wells and Hani Zainulbhai - Using a Web Diary Survey to Measure Out-of-Home Media Consumption and Engagement
Craniofacial Regeneration, Stem Cells, and Clinical Cell Therapy...Where are we now? (February 10, 2022 12:00pm) https://events.umich.edu/event/91853 91853-21683555@events.umich.edu Event Begins: Thursday, February 10, 2022 12:00pm
Location:
Organized By: Office of Research School of Dentistry

Major M. Ash Collegiate Professor of Periodontics
Department of Periodontics and Oral Medicine
University of Michigan

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Presentation Wed, 02 Feb 2022 08:43:33 -0500 2022-02-10T12:00:00-05:00 2022-02-10T13:00:00-05:00 Office of Research School of Dentistry Presentation Darnell Kaigler, Jr., D.D.S, M.S., Ph.D.
Statistics Department Seminar Series: Elizabeth Ogburn, Associate Professor, Department of Biostatistics, Johns Hopkins University (February 11, 2022 10:00am) https://events.umich.edu/event/90167 90167-21668501@events.umich.edu Event Begins: Friday, February 11, 2022 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Nonsense associations can arise when an exposure and an outcome of interest exhibit similar patterns of dependence. Confounding is present when potential outcomes are not independent of treatment. This talk will describe how confusion about these two phenomena results in shortcomings in popular methods in three areas: causal and statistical inference with social network data; causal inference with multiple treatments and unmeasured confounding; and causal inference with spatial data. For each of these three areas I will demonstrate shortcomings of existing methods and describe new methods that were inspired by careful consideration of dependence and confounding.


Betsy Ogburn is an Associate Professor in the Department of Biostatistics at Johns Hopkins University and founder of the COVID-19 Collaboration Platform.

https://www.eogburn.com/

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Workshop / Seminar Wed, 02 Feb 2022 14:09:05 -0500 2022-02-11T10:00:00-05:00 2022-02-11T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Betsy Ogburn
RNA Faculty Candidate Seminar (February 14, 2022 4:00pm) https://events.umich.edu/event/89617 89617-21664565@events.umich.edu Event Begins: Monday, February 14, 2022 4:00pm
Location: Taubman Biomedical Science Research Building
Organized By: Center for RNA Biomedicine

In-person/Hybrid seminar co-hosted by the Center for RNA Biomedicine, the Department of Biological Chemistry and the Department of Biophysics

Talk title: “Mechanisms of co-transcriptional ribonucleoprotein assembly”

Keywords: RNA, RNP, ribosome assembly, transcription, single-molecule fluorescence

If you are having trouble registering, please contact Martina Jerant at mjerant@umich.edu

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Lecture / Discussion Thu, 02 Dec 2021 15:28:59 -0500 2022-02-14T16:00:00-05:00 2022-02-14T17:00:00-05:00 Taubman Biomedical Science Research Building Center for RNA Biomedicine Lecture / Discussion Margaret (Maggie) Rodgers, Johns Hopkins University
Complex Systems Seminar | Markov genealogy processes for exact phylodynamic inference (February 15, 2022 11:30am) https://events.umich.edu/event/92259 92259-21688751@events.umich.edu Event Begins: Tuesday, February 15, 2022 11:30am
Location: Weiser Hall
Organized By: The Center for the Study of Complex Systems

THIS WILL BE A HYBRID SEMINAR
WEISER HALL ROOM 747 (limit 30, mask required)
https://umich.zoom.us/j/96616169868 Passcode: CSCS

Abstract: We describe an approach to phylodynamics that unifies and extends existing likelihood-based methods for extracting information from virus genealogies to parameterize pathogen transmission models. While existing methods rely on approximations that are often violated in practice, our approach yields exact expressions for the likelihood. Specifically, we introduce a class of genealogy-valued Markov processes, induced by population-scale transmission models and show how these lead to a nonlinear filtering equation. The theory is mathematically rigorous and leads directly to computationally efficient inference algorithms.

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Workshop / Seminar Mon, 14 Feb 2022 14:55:28 -0500 2022-02-15T11:30:00-05:00 2022-02-15T13:00:00-05:00 Weiser Hall The Center for the Study of Complex Systems Workshop / Seminar Aaron King
CANCELLED - Laura Lindberg - Quality of Abortion Reporting in the US and Pathways to Improvement (February 16, 2022 12:00pm) https://events.umich.edu/event/91431 91431-21679571@events.umich.edu Event Begins: Wednesday, February 16, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

Laura Lindberg
Principal Research Scientist, Guttmacher Institute

Dr. Laura Lindberg is a Principal Research Scientist at the Guttmacher Institute, where she has worked for nearly two decades. As a social demographer, Dr. Lindberg focuses on measuring the trends, determinants and consequences of sexual and reproductive health in the U.S. population and working to improve the quality of survey data on sexual and reproductive behaviors. She currently has two NICHD grants on measurement of core demographic constructs, abortion and contraceptive failure rates. Over the course of her career, she has conducted policy-related research on adolescent sexual behaviors, sex education, adolescent preventive services, unintended pregnancy and contraceptive use. Dr. Lindberg received her undergraduate degree from Princeton University; she earned her MA and PhD in sociology at the University of Michigan, where her favorite class was on survey research methods with Bob Groves.

Quality of Abortion Reporting in the US and Pathways to Improvement

Despite the fact that an estimated one in five pregnancies in the United States end in induced abortion, abortion remains a highly sensitive, stigmatized and thus difficult-to-measure behavior. I will present on a body of recent research designed to help to develop new techniques and improve existing methodologies for measuring abortion reporting. First, I share a series of quantitative analyses to identify the scope and correlates of abortion underreporting for three of the most commonly used national fertility surveys in the United States: the National Survey of Family Growth, the National Longitudinal Survey of Youth 1997, and the National Longitudinal Study of Adolescent to Adult Health. These analyses informed the development of new question designs were explored in cognitive interviews and experimentally tested and evaluated in a national survey. Abortion underreporting in population surveys has far-reaching implications for research in sexual and reproductive health and maternal and child health.

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Lecture / Discussion Mon, 14 Feb 2022 09:50:07 -0500 2022-02-16T12:00:00-05:00 2022-02-16T13:00:00-05:00 Off Campus Location Michigan Program in Survey and Data Science Lecture / Discussion February 16th Seminar Cancelled
MIPSE Seminar | Fundamental Tests with Antihydrogen Atoms (February 16, 2022 3:30pm) https://events.umich.edu/event/90465 90465-21671092@events.umich.edu Event Begins: Wednesday, February 16, 2022 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Motivated by the baryogenesis problem (the scarcity of antimatter in the University), CERN's ALPHA collaboration has been studying the properties of antihydrogen atoms. Since first trapping antiatoms in 2010, we have learned to routinely trap over 1000 antiatoms simultaneously, and keep the antiatoms trapped for many tens of thousands of seconds. We have been able to measure the 1S-2S and hyperfine bandwidths to the 10kHz level, which, on some scales, exceeds the accuracy of the best CPT tests. We have been able to laser cool the antiatoms, which should lead to better spectral measurement, and we have also measured the antihydrogen charge to 0.7ppb. We are constructing a new apparatus designed to measure the antimatter g to 1%, which will be a test of the weak equivalence principle. Antihydrogen is created by mixing positron and antiproton single species plasmas. The plasmas must be very cold (~10K) and, for single species plasmas, dense (~108 cm-3). Arguably, the most difficult problems in these experiments stem from achieving these parameters as all the other issues, though complex, can be solved with standard techniques of atomic and laser physics. This talk will describe some of these plasma issues and some of our physics results.

About the Speaker:
Dr. Joel Fajans is a Professor of Physics at U.C. Berkeley. He received his PhD in experimental plasma physics under George Bekefi at MIT studying free electron lasers before assuming a post-doc at the University of California at San Diego with John Malmberg and Tom O'Neil on nonneutral plasmas. Since then, his career has concentrated on basic plasma physics and nonlinear dynamics experiments, most recently aimed towards the creation and trapping of antihydrogen. He is a fellow of the American Physical Society and a recipient of the APS 2011 John Dawson Award for Excellence in Plasma Physics Research.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Wed, 05 Jan 2022 09:29:12 -0500 2022-02-16T15:30:00-05:00 2022-02-16T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Joel Fajans
Oral Health for All: Opportunities for Improvement and Understanding (February 17, 2022 1:00pm) https://events.umich.edu/event/91753 91753-21683050@events.umich.edu Event Begins: Thursday, February 17, 2022 1:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

Dr. Jennifer Webster-Cyriaque is the deputy director of National Institute of Dental and Craniofacial Research, National Institutes of Health. An accomplished clinician, researcher, and leader, Dr. Webster-Cyriaque had previously served as a faculty member at the University of North Carolina (UNC) schools of dentistry and medicine for more than two decades.

As a tenured full professor at UNC, Dr. Webster-Cyriaque also served as the attending on clinical service at the UNC Hospital’s dental clinic. While there, she led research into a potential etiologic agent for salivary gland disease in patients living with HIV, assessed the oral microbiome and its implications for cancer-causing viruses, and studied the impact of the oral microbiome and oral health on HIV outcomes.

In addition to her research, Dr. Webster-Cyriaque has held leadership roles as the chair/vice chair of the Oral HIV/AIDS Research Alliance, as research director at the National Dental Association Foundation, as director of postdoctoral CTSA training, along with multiple roles within the American Association for Dental, Oral, and Craniofacial Research and the International Association for Dental Research. Since 2004, she has led the UNC Malawi project and provided assistance in founding Malawi’s first dental school in 2019. Dr. Webster-Cyriaque earned her PhD in microbiology/immunology from the University of North Carolina-Chapel Hill in 1998, her DDS from SUNY Buffalo in 1992, and her BA in biology and interdisciplinary social science from SUNY Buffalo in 1988.

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Presentation Tue, 01 Feb 2022 08:51:49 -0500 2022-02-17T13:00:00-05:00 2022-02-17T14:00:00-05:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Presentation Jennifer Webster-Cyriaque, DDS, PhD
Statistics Department Seminar Series: Peter Ralph, Associate Professor, Department of Mathematics, University of Oregon (February 18, 2022 10:00am) https://events.umich.edu/event/90168 90168-21668502@events.umich.edu Event Begins: Friday, February 18, 2022 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: Computer simulations of evolving populations are a crucial tool for exploration, inference, and validation with population genomic data. However, due to the size of the genome, simulation of large, sexual populations - especially across geography - has been a major challenge. I will discuss how efforts to make these simulations feasible has led to development of a new data structure, the succinct tree sequence, that stores genetic variation data orders of magnitude more efficiently as usual methods, while at the same time encoding the entire genealogical history of every genome and making computation with these genomes orders of magnitude more efficient. I will also discuss some applications


Peter Ralph is an Associate Professor in the Department of Mathematics at the University of Oregon. He completed his Ph.D. in Statistics at UC Berkeley, advised by Steve Evans.

https://math.uoregon.edu/profile/plr

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Workshop / Seminar Fri, 11 Feb 2022 15:58:19 -0500 2022-02-18T10:00:00-05:00 2022-02-18T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Peter Ralph
TEDxUofM 2022 Conference: SHATTERPROOF (February 18, 2022 6:00pm) https://events.umich.edu/event/90984 90984-21675132@events.umich.edu Event Begins: Friday, February 18, 2022 6:00pm
Location: Power Center for the Performing Arts
Organized By: TEDxUofM

TEDxUofM is a university-wide initiative to galvanize the community for an event like no other; filled with inspiration, discovery, and excitement. Borrowing the template from the world-renowned TED conference, TEDxUofM aims to bring a TED-like experience to the University of Michigan. Our vision is to showcase the most fascinating thinkers and doers, the “leaders and best” in Michigan terms, for a stimulating day of presentations, discussions, entertainment, and art that will spark new ideas and opportunities across all disciplines. Our conference will feature 8 speakers, 3 performing groups, and interactive labs/activities for attendees!

Our theme for this year’s conference is SHATTERPROOF. Through a time of fragmentation and dissonance, individuals and communities have showcased an incredible ability to withstand adversity. Resilience is found in all of us despite the size of the challenge. We use our voices to empower each other. We use ideas to drive us forward. We refuse to crack under pressure. We are shatterproof. As we set the stage with this spirit, our goal is for attendees to discover what being shatterproof means to them.

Visit www.tedxuofm.com to get tickets to our Conference!

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Conference / Symposium Thu, 13 Jan 2022 17:56:24 -0500 2022-02-18T18:00:00-05:00 2022-02-18T21:30:00-05:00 Power Center for the Performing Arts TEDxUofM Conference / Symposium TEDxUofM Conference Flyer
Activities & Experiences of the Climate Hazards, Housing, & Health (CHHH) Community-Academic Partnership (February 22, 2022 12:00pm) https://events.umich.edu/event/92173 92173-21687628@events.umich.edu Event Begins: Tuesday, February 22, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Registration Required https://umich.zoom.us/webinar/register/WN_di5aDB3VTAa8U8sLrsOJtA

Zachary Rowe (Friends of Parkside, Detroit) and Carina Gronlund (Institute for Social Research, University of Michigan) will discuss issues of climate and health in Detroit.

Moderated by Marie O’Neill (School of Public Health, University of Michigan).

Recordings of the webinar series are posted to the M-LEEaD YouTube Channel https://www.youtube.com/channel/UC2MD-2fqFHTU3ODB8BHEDTg.

Organized by the Community Engagement Core and Integrated Health Sciences Core of the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD).

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Lecture / Discussion Wed, 09 Feb 2022 12:39:50 -0500 2022-02-22T12:00:00-05:00 2022-02-22T12:50:00-05:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion R&R: Residents and Researchers Tuesday Talks at 12 on environment, health, and community
Weekly Seminar for DCMB / CCMB (February 23, 2022 4:00pm) https://events.umich.edu/event/92060 92060-21686457@events.umich.edu Event Begins: Wednesday, February 23, 2022 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

In the Peixoto lab we use genomic approaches to understand gene expression and its epigenetic regulation in response to learning and sleep deprivation, and its alteration in autism spectrum disorders. This requires combining behavioral paradigms in mice, molecular biology and the analysis of high-throughput data in the brain in vivo. It also requires using the right data analysis tools to be able to capture the effect of learning or sleep in the context of an ever-active brain. In this talk we will discuss the effects of learning on chromatin accessibility and the effects of sleep loss in gene expression, with an emphasis on how data analysis influences our ability to detect novel and reproducible biology.

Short bio:

Lucia Peixoto received her bachelor’s degree in Biochemistry from the Universidad de la Republica in her native Uruguay in 2002. She subsequently earned her Ph.D. at The University of Pennsylvania under the mentorship of Dr. David S. Roos, using genomic and computational biology approaches to understand host-pathogen interactions. She completed her postdoctoral training in Neuroscience with Dr. Ted Abel at The University of Pennsylvania in 2015. During her fellowship, she was also a trainee at the Training Program in Neurodevelopmental disabilities at the Children’s Hospital of Philadelphia. As a trainee at CHOP, she completed a clinical internship at the Center for Autism Research under the supervision of Dr. Robert Schultz. She became an Assistant Professor at Washington State University in 2015 and has since been recognized with a K01 Early Career Faculty award from NIH/NINDS and a pilot award from the Simons Foundation Autism Research Initiative. She is also a member of the board of directors of the International Society of computational biology (ISCB) and cochair the Equity, Diversity and Inclusion committee of ISCB. Her lab uses behavior, electrophysiology, molecular biology and genomic approaches to understand how sleep and learning modulate transcription and how this may be altered in Autism Spectrum Disorders.

Zoom livestream link: https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Workshop / Seminar Mon, 07 Feb 2022 14:54:44 -0500 2022-02-23T16:00:00-05:00 2022-02-23T17:00:00-05:00 Off Campus Location DCMB Seminar Series Workshop / Seminar
LHS Collaboratory (February 24, 2022 12:00pm) https://events.umich.edu/event/90079 90079-21667713@events.umich.edu Event Begins: Thursday, February 24, 2022 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

The session will describe the landscape history, current status, and future of federated health data networks that are used to support a Learning Health System. Dr. Brown will describe the creation, infrastructure, operation, and uses of several networks from the perspective of a network coordinating center. Dr. Harris will describe insights from participating in multiple networks as a network partner, including infrastructure, governance, and operational lessons learned.

Presenters:
Jeffrey Brown, PhD
Dr. Brown is the inventor of PopMedNet, an open-source software platform that facilitates creation and operation of distributed health data networks.

Marcelline Harris, Ph.D., RN, FACMI
Associate Professor Emerita
Department of Systems, Populations and Leadership
University of Michigan School of Nursing

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Lecture / Discussion Sat, 29 Jan 2022 11:26:41 -0500 2022-02-24T12:00:00-05:00 2022-02-24T13:30:00-05:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Collaboratory logo
Statistics Department Seminar Series: Jacob Bien, Associate Professor, Data Sciences and Operations, Marshall School of Business, University of Southern California (February 25, 2022 10:00am) https://events.umich.edu/event/90169 90169-21668503@events.umich.edu Event Begins: Friday, February 25, 2022 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In many fields, data are routinely being collected at finer resolutions than would previously have been possible. While in principle higher resolution data should always be preferred, it can lead to a mismatch between the level of measurement and the level of scientific relevance. Researchers are therefore confronted with the challenge of choosing the appropriate resolution level for data analysis. On the one hand, naively applying data analysis methods at the fine scale of measurement may make it hard to detect scientifically relevant phenomena if they occur at coarser levels. On the other hand, coarsening the data before data analysis risks missing out on fine-scale phenomena should they exist.

In this talk, we propose data-adaptive tree-structured aggregation as a framework for addressing this challenge. We consider this problem in multiple contexts, including regression, Gaussian graphical models, and multiple hypothesis testing. The works described include collaborations with Xiaohan Yan, Christian Müller, Ines Wilms, Adel Javanmard, Simeng Shao, and Léo Simpson.

http://faculty.marshall.usc.edu/Jacob-Bien/

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Workshop / Seminar Fri, 18 Feb 2022 15:37:45 -0500 2022-02-25T10:00:00-05:00 2022-02-25T11:00:00-05:00 Off Campus Location Department of Statistics Workshop / Seminar Jacob Bien
Complex Systems Seminar: Promoting the use of agent-based modeling in scientific inquiry: a Learning Sciences approach (March 8, 2022 11:30am) https://events.umich.edu/event/92858 92858-21697300@events.umich.edu Event Begins: Tuesday, March 8, 2022 11:30am
Location: Off Campus Location
Organized By: The Center for the Study of Complex Systems

Virtual Seminar
https://umich.zoom.us/j/96616169868
Password: CSCS (all caps)

Abstract: Agent-based modeling provides a powerful computational infrastructure to construct dynamic representations of scientific phenomena that can augment analytical models in unique and meaningful ways. However, although it is used extensively in the field of complex systems and embraced by social scientists, only a handful of researchers in natural sciences incorporate agent-based modeling components into their theoretical investigations. In this talk, I will present findings from two of my prior studies on reconstructing existing theoretical models through agent-based modeling and I will argue that the tools and methods of Learning Sciences can help us cultivate productive ways of augmenting existing theoretical studies with agent-based components in a manner that is commensurate with scientists’ ways of thinking, which would in turn accelerate adoption of the complexity lens by more and more natural scientists.

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Workshop / Seminar Tue, 08 Mar 2022 11:04:29 -0500 2022-03-08T11:30:00-05:00 2022-03-08T13:00:00-05:00 Off Campus Location The Center for the Study of Complex Systems Workshop / Seminar Ümit Aslan
"Using Epigenome Actuation to Advance Epigenetic Therapy for Triple Negative Breast Cancer" (March 8, 2022 4:00pm) https://events.umich.edu/event/91191 91191-21677135@events.umich.edu Event Begins: Tuesday, March 8, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following seminar with guest speaker Karmella A. Haynes, PhD. Dr. Haynes is an Assistant Professor of Biomedical Engineering at Emory University.

Her talk is entitled, "Using Epigenome Actuation to Advance Epigenetic Therapy for Triple Negative Breast Cancer".

Faculty Host: Laura Buttitta, PhD, LSA-Molecular, Cellular, & Developmental Biology

For more information, please email Organogenesis@umich.edu(link

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Lecture / Discussion Tue, 18 Jan 2022 14:08:23 -0500 2022-03-08T16:00:00-05:00 2022-03-08T17:00:00-05:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion Flyer for the Event
Ipek Bilgen and Amelia Burke-Garcia - The Use of Advanced Social Media Targeting Methodology During Recruitment of Hard-to-Reach Audiences (March 9, 2022 12:00pm) https://events.umich.edu/event/91859 91859-21683564@events.umich.edu Event Begins: Wednesday, March 9, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

The Use of Advanced Social Media Targeting Methodology During Recruitment of Hard-to-Reach Audiences
Ipek Bilgen and Amelia Burke-Garcia

One of the major benefits of social media ad-based survey recruitment is the use of various types of data to target ads to users of these platforms. To target users of social media, researchers can use the basic demographic and geographic that social media platforms currently provide, or they can use enhanced data that can be embedded within the social media platforms supplied by third party providers based on external data sources, e.g., historical purchase data. We will examine whether and how much this enhanced data can impact ad based social media recruitment capabilities to reach niche and hard-to-reach audiences.

To investigate the targeting efficiency, quality, and cost differences among these two approaches that can be used to target audiences within social media platforms, NORC piloted a strategic initiative research study in 2020. A web survey was constructed using existing items from national surveys on individual’s health and online habits, as well as new items related to life changes during the pandemic. Two main audience groups that are generally hard to recruit through probability-based studies were targeted – young adults, ages 18-24, and people with low education (defined as anyone who has completed high school as the highest level of education or lower). Five sets of tailored ads with unique URLs that linked to a web-based survey were designed and launched via Facebook and Instagram. Two sets used basic targeting to recruit the sample and the other three used the enhanced targeting. This brown bag will present the design of the study, our approach to the ads and targeting, and what we learned through our examination of the differences between the samples obtained from basic and advanced targeting on the dimensions of recruited sample composition, survey estimates, and recruitment costs.

Dr. Ipek Bilgen is a Senior Research Methodologist in the Methodology and Quantitative Social Sciences (MQSS) Department at NORC at the University of Chicago. Bilgen is AmeriSpeak Panel’s lead research methodologist. She also directs web and emerging technologies strategic initiative at NORC. She has over a decade of experience in applied survey methods and received both her Ph.D. and M.S. from the Survey Research and Methodology (SRAM) Program at the University of Nebraska-Lincoln.

Bilgen has published and co-authored articles in Journal of Official Statistics, Public Opinion Quarterly, Survey Practice, Social Currents, Social Science Computer Review, Field Methods, SAGE Research Methods, and Quality and Quantity on issues related to interviewing methodology, web surveys, internet sampling and recruitment approaches, cognition and communication, and measurement error in surveys. Her current research investigates panel recruitment and retention, total survey error sources in probability-based online panels, the use of web and emerging technologies in surveys, and questionnaire design and survey implementation issues. Her research also examines studies related to the use of auxiliary data for improved efficiency in surveys that use address-based sampling (ABS) and active survey recruitment through social media and search engines.

Bilgen is currently serving as Associate Editor of Public Opinion Quarterly (POQ). In the past, she has served as an elected member of American Association for Public Opinion Research (AAPOR)’s Executive Council as Membership and Chapter Relations Chair. She has also served on Midwest Association for Public Opinion Research (MAPOR)’s Executive Council as President, Vice President, Conference Chair, and Secretary Treasurer.

Dr. Amelia Burke-Garcia is a seasoned health communications professional with nearly 20 years of experience in health communication program planning, implementation and evaluation, with specific expertise in developing and evaluating digital and social media communication and research. At NORC, she leads the organization's Digital Strategy and Outreach Program Area, where she designs, develops, and implements new digital and mobile data collection methodologies and communication solutions. Most recently, she acted as director for the award-winning How Right Now/Que Hacer Ahora campaign, which is aimed at increasing people’s ability to cope and be resilient amidst the COVID-19 pandemic. She currently leads two grants focused on exploring vaccine hesitancy amongst communities of color which build on her earlier work exploring messages and motivations of vaccine hesitant or refusing social media influencers (findings from which were published in Vaccine in 2020). Over the course of her career, Dr. Burke-Garcia has spearheaded some of the most innovative communication programs and studies on a variety of health topics including designing a targeted social media intervention with mommy bloggers to help social media users lower their risk for breast cancer and leveraging MeetUp groups and the Waze mobile application to move people to action around flu vaccination and HIV testing, respectively. She is the author of the book entitled, Influencing Health: A Comprehensive Guide to Working with Online Influencers and has been named to VeryWellHealth.com’s list of 10 Modern Female Innovators Shaking Up Health Care. She holds a PhD in Communication from George Mason University, a Master’s degree in Communication, Culture, and Technology from Georgetown University, and a joint honours Bachelor’s degree in International Development Studies and Humanistic Studies from McGill University.

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Lecture / Discussion Mon, 07 Feb 2022 12:19:11 -0500 2022-03-09T12:00:00-05:00 2022-03-09T13:00:00-05:00 Off Campus Location Michigan Program in Survey and Data Science Lecture / Discussion The Use of Advanced Social Media Targeting Methodology During Recruitment of Hard-to-Reach Audiences
Physiological Sensing to Indicate Driver Takeover Abilities — CCAT Research Review (March 9, 2022 2:00pm) https://events.umich.edu/event/92203 92203-21688056@events.umich.edu Event Begins: Wednesday, March 9, 2022 2:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

The emerging level 3 autonomous vehicle (L3AV) can perform all aspects of the driving task and allow for complete disengagement of drivers (e.g., sit back and relax) under certain driving scenarios including immediate response (e.g., emergency braking). However, this still requires the driver to be prepared for takeover within a few seconds of warning. Being able to measure and predict the takeover performance (TOP) ahead of time and issue adequate warnings is critical to ensure driver comfort, trust, and safety in the system and acceptance of the technology.

A necessary undertaking in this process is to develop a robust approach to understand the drivers’ capabilities to take over the vehicle safely and promptly in L3 AV under different driving and disengagement scenarios. In this project, we propose an integrated treatment of the drivers’ TOP measured through multimodal physiological features and driving environment data in L3 AVs. We will present the results of data collected from 20 drivers. The drivers were presented with different secondary tasks and driving scenarios in a simulator and their physiological responses were collected using different sensing devices such as electroencephalogram (EEG), galvanic skin response (GSR), and heart rate (HR). The presentation will highlight the relationship between the driver's physiological state such as level of engagement with the secondary task and their TOP.

More about this research: https://myumi.ch/Axbod

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Livestream / Virtual Thu, 10 Feb 2022 11:47:19 -0500 2022-03-09T14:00:00-05:00 2022-03-09T15:00:00-05:00 Off Campus Location Center for Connected and Automated Transportation Livestream / Virtual Decorative Image for the CCAT Research Review with Carol Menassa, Vineet Kamat, Da Li, and Julian Brinkley. It features the presentation title 'Can Physiological Sensing Indicate Driver Takeover Abilities in Lvl 3 Automation?' and a test subject using a driving simulator.
MIPSE Seminar | Z-pinch Research at UC San Diego (March 9, 2022 3:30pm) https://events.umich.edu/event/90466 90466-21671093@events.umich.edu Event Begins: Wednesday, March 9, 2022 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The Z-pinch is one of the most well-studied methods for high energy density plasma generation. Z-pinches have been used for applications such as thermonuclear fusion and as intense x-ray sources. The High Energy Density Physics Group at UC San Diego has an extensive experimental and modeling program across a variety of Z-pinch devices. The focus in this presentation is on gas puff Z-pinches and Dense Plasma Focus (DPF). These devices are highly susceptible to the Magneto Rayleigh-Taylor Instability during the implosion which can disrupt the plasma column. Experiments were conducted on the CESZAR linear transformer driver (LTD) with ~500 kA, 160 ns current pulses in a gas puff configuration. The effect of varying gas species was studied using metrics like instability amplitude and energy coupling. We demonstrate that low-impedance LTDs can implode a variety of gas puff loads with an energy coupling efficiency of ~10%. 2-D magnetohydrodynamic simulations of Ne-liner, deuterium-target gas-puff loads show that the tradeoff between stability and yield can be reduced by density profile tailoring – adding a second liner. Work on DPFs has focused on a 4.4 kJ, 280 kA DPF at UCSD and the 2 MJ, 2-3 MA Gemini DPF at the Nevada Test Site. Experiments on the UCSD DPF have shown a significant effect of insulator surface conditioning on x-ray production. The Gemini experiments focused on rare gas additions to deuterium. MHD simulations of the Gemini DPF provide evidence of an increasing fusion yield and tighter current sheaths with increased dopant concentration.

About the Speaker:
Farhat Beg is a Professor of Engineering Physics at the Department of Mechanical and Aerospace Engineering at the University of California, San Diego. He received his Ph.D. from Imperial College London. His expertise is in the field of laser plasma interaction, pulsed power-driven X- and Z-pinches, and neutron sources. He has published over 250 papers in refereed journals, including Nature, Nature Physics, Nature Photonics and Physical Review Letters, with total citations exceeding 9000 and with an H-index of 50, according to the ISI Web of Knowledge. He is the fellow of the American Physical Society, the Institute of Electrical and Electronics Engineers (IEEE) and the American Association for the Advancement of Science (AAAS). He has been a winner of the Department of Junior Faculty Award (2005) and IEEE Early Career Award (2008). This year he received IEEE Plasma Science and Applications Award. He has served as the Chair of the High-Energy Density Science Association (HEDSA) in 2009/10 and in 2017/2019 and NIF/Jupiter User group in 2017/2019.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Wed, 05 Jan 2022 09:40:04 -0500 2022-03-09T15:30:00-05:00 2022-03-09T16:30:00-05:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Farhat Beg
Data Science in Health Disparities Research Symposium (March 11, 2022 9:00am) https://events.umich.edu/event/91976 91976-21684826@events.umich.edu Event Begins: Friday, March 11, 2022 9:00am
Location: Palmer Commons
Organized By: DCMB Seminar Series

Additional speakers on the topics of:

How data science can be used to understand racial health disparities

How data science with biased data exacerbates health disparities

Lunch and discussion sessions following the talks.

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Workshop / Seminar Mon, 07 Feb 2022 10:37:38 -0500 2022-03-11T09:00:00-05:00 2022-03-11T15:00:00-05:00 Palmer Commons DCMB Seminar Series Workshop / Seminar
Fourth Annual Likert Workshop - Intersections between Cross-Cultural Survey Research and Cross-Cultural Psychology (March 11, 2022 11:00am) https://events.umich.edu/event/92407 92407-21691038@events.umich.edu Event Begins: Friday, March 11, 2022 11:00am
Location: Off Campus Location
Organized By: Michigan Program in Survey and Data Science

Fourth Annual Likert Workshop
Intersections between Cross-Cultural Survey Research and Cross-Cultural Psychology

ONLINE REGISTRATION REQUIRED (Free Virtual Workshop)

 11:00-11:10 - Welcome. Fred Conrad, Director, Program in Survey and Data Science, University of Michigan.

 11:10-11:30 - Introduction. Tim Johnson, Professor Emeritus, University of Illinois at Chicago, Senior Fellow, Center of Excellence in Survey Research, NORC.

 11:30-12:00 - Moving a cross-national general survey from face-to-face to self-completion data collection: a discussion of the cross-national and cross-cultural challenges. Rory Fitzgerald, Director, European Social Survey, City, University of London, U.K.

 12:00-12:10 - Break

 12:10-12:40 - Assessing measurement invariance: Can we make a dead-end road into a highway? Jan Cieciuch, Professor, Psychology, Cardinal Wyszynski University in Warsaw, Poland, URPP Social Networks, University of Zurich, Switzerland Eldad Davidov, Professor, Sociology, University of Cologne, Germany, Sociology and URPP Social Networks, University of Zurich, Switzerland Peter Schmidt, Professor Emeritus, ZEU, University of Giessen, Germany, Psychosomatics, University of Mainz, Germany Daniel Seddig, Professor, Sociology, University of Passau, Germany, University of Cologne, Germany.

 12:40-1:10 - Culture, language and measurement of health. Sunghee Lee, Research Associate Professor, Program in Survey and Data Science, University of Michigan.

 1:10-1:20 - Break

 1:20-1:50 - Voicing politics: How language shapes public opinion. Efrén O. Pérez, Professor, Political Science and Psychology, Director, Race, Ethnicity, Politics & Society (REPS) Lab, UCLA.

 1:50-2:20 - What may this mean? How cultural mindsets influence conversational inferences. Daphna Oyserman, Dean’s Professor, Psychology, University of Southern California, Norbert Schwarz, Provost Professor, Psychology and Marketing, University of Southern California.

 2:20-2:30 - Closing Discussion, Q&A.

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Workshop / Seminar Wed, 16 Feb 2022 08:54:13 -0500 2022-03-11T11:00:00-05:00 2022-03-11T14:30:00-05:00 Off Campus Location Michigan Program in Survey and Data Science Workshop / Seminar Fourth Annual Likert Workshop
New generation of neurophotonics for multiscale access of mammalian brain (March 11, 2022 12:00pm) https://events.umich.edu/event/93013 93013-21699104@events.umich.edu Event Begins: Friday, March 11, 2022 12:00pm
Location: Chemistry Dow Lab
Organized By: LSA Biophysics

Human brain as the center of the nervous system controls our physiology, consciousness, and behavior. The function of the brain relies on the interactions of tens of billions of neurons through tens of trillions of synapses. Gaining precise knowledge of neural circuits relies on innovative and transformative tools for quantitative measurement of cellular dynamics and signaling in the live brain. Our lab works at the interface of optical engineering, device fabrication, image processing, and neuroscience to deliver enabling tools for neuroscience research. Specifically, we are working on three frontiers. First, the major challenge of cellular resolution function recording is the superficial access depth. Current methods are limited to ~ 1 mm depth, insufficient to access deep brain regions. We have developed Clear Optically Matched Panoramic Access Channel Technique (COMPACT) for deep-brain large-scale neurophotonic interface. I will present the results of applying COMPACT for deep-brain calcium imaging. Second, high-performance glutamate sensors and voltage indicators are on the horizon. Seeing information flow at millisecond time scale with subcellular resolution among neural circuits in the live mammalian brain is about to become a reality. However, currently available imaging tools are insufficient to keep up with the sensor response. We have developed an optical gearbox that can convert existing scopes for such high-speed measurement. I will present the results of in vivo kHz imaging. Third, cellular resolution recording has been limited to animal models. In comparison, fMRI and ultrasound can be applied to human brain. Can we leverage the advance of cellular resolution recording to address the key challenges of human brain measurement modalities? I will discuss the latest progress on the multimodal imaging of mammalian brain.

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Workshop / Seminar Fri, 04 Mar 2022 12:57:07 -0500 2022-03-11T12:00:00-05:00 2022-03-11T13:30:00-05:00 Chemistry Dow Lab LSA Biophysics Workshop / Seminar Chemistry Dow Lab
Integrating intersectionality into Environmental Health Sciences (March 15, 2022 12:00pm) https://events.umich.edu/event/92997 92997-21698985@events.umich.edu Event Begins: Tuesday, March 15, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

*Registered required.

Ami Zota, ScD, MS, is an Associate Professor in the Department of Environmental & Occupational Health at George Washington University's Milken School of Public Health. Dr. Zota’s work seeks to secure environmental justice and improve health equity through advancements in science, policy, and clinical practice. Her research identifies novel pathways linking social disparities, environmental exposures, and reproductive and children’s health.

The environmental research seminar series is organized by the Integrated Health Sciences Core of the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD). More information about M-LEEaD and upcoming events can be found here: http://mleead.umich.edu/index.php

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Lecture / Discussion Fri, 04 Mar 2022 09:34:10 -0500 2022-03-15T12:00:00-04:00 2022-03-15T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Integrating intersectionality into Environmental Health Sciences
“Mechanobiology of vertebrate gut morphogenesis" (March 15, 2022 4:00pm) https://events.umich.edu/event/92788 92788-21695466@events.umich.edu Event Begins: Tuesday, March 15, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following seminar with guest speaker Nandan L. Nerurkar, PhD, Assistant Professor of Biomedical Engineering at Columbia University.

The talk is entitled, "Mechanobiology of vertebrate gut morphogenesis."

Faculty Host: Brendon Baker, PhD, Biomedical Engineering

For more information, please email Organogenesis@umich.edu

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Lecture / Discussion Thu, 24 Feb 2022 21:22:04 -0500 2022-03-15T16:00:00-04:00 2022-03-15T17:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion Nerurkar Flyer
“The Salivary Glands: Robust Sites for Infection and Transmission of SARS-CoV-2” (March 17, 2022 12:00pm) https://events.umich.edu/event/92751 92751-21695193@events.umich.edu Event Begins: Thursday, March 17, 2022 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

BIOGRAPHY
Born: August 3rd, 1981, Defiance, Ohio, United States of America

LICENSES & CERTIFICATIONS
Diplomate, Oral and Maxillofacial Pathology – American Board of Oral and Maxillofacial Pathology
Dental License(s) – Unrestricted Dental License, Commonwealth of Pennsylvania, DS039850
DEA Registration – US Department of Justice
CPR Certification – American Red Cross

HONORS, AWARDS, & NOTEWORTHY INVITED TALKS.
2021 American College of Rheumatology Convergence, Invited Speaker, “Epigenetics of Sjogren’s Syndrome.” November 2021. >600 Attendees/Views.

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Lecture / Discussion Tue, 01 Mar 2022 11:08:51 -0500 2022-03-17T12:00:00-04:00 2022-03-17T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Lecture / Discussion Blake Warner, DDS, PhD, MPH Assistant Clinical Investigator Chief of the Salivary Disorders Unit and the Sjogren’s Syndrome Clinic NIH National Institute of Dental and Craniofacial Research
Infusing Human Factors and Systems Approach into Health Care: Examples, Opportunities, and the Future (March 17, 2022 3:00pm) https://events.umich.edu/event/92822 92822-21702630@events.umich.edu Event Begins: Thursday, March 17, 2022 3:00pm
Location: Off Campus Location
Organized By: U-M Industrial & Operations Engineering

Seminar Abstract:
Within the last two decades, there has been an increasing emphasis on the use of human factors engineering to improve health care quality and safety. In this presentation, Dr. Gurses will describe how human factors and systems engineering principles and approaches can be used (1) to systematically identify hazards to patient safety and health care worker safety given the complex, adaptive, nonlinear nature of health care work systems; and (2) to develop effective interventions with the purpose of eliminating and/or mitigating these hazards and improving adaptive capacity and resilience of the frontline care work. Application examples will be from a variety of health care settings (i.e., emergency department, operating rooms, home care), and focus areas (e.g., safety of care transitions/ handoffs, COVID-19 personal protective equipment use, and the safety of air flow management in clinical settings).

The Departmental Seminar Series is open to all. U-M Industrial and Operations Engineering graduate students and faculty are especially encouraged to attend.

Presenter Bio:
Ayse P. Gurses, Ph.D., MS, MPH

Director, Center for Health Care Human Factors, Armstrong Institute, Johns Hopkins Medicine

Professor, Schools of Medicine, Bloomberg Public Health, Whiting Engineering, Johns Hopkins University

Dr. Gurses is a globally recognized researcher, educator, and thought leader in infusing human factors engineering principles and methods into health care with the goal to design better and safer work environments and systems for improving patient safety and health care worker safety. She is the Founding Director of the Center for Health Care Human Factors at the Johns Hopkins Armstrong Institute and Professor in the Johns Hopkins University Schools of Medicine, Bloomberg Public Health and Whiting Engineering. She is the author of more than 100 peer-reviewed publications on human factors engineering, patient safety and quality of care, and health care worker safety.
Dr. Gurses has conducted research in a variety of care settings, including hospitals, ambulatory care, long-term care, and home care, as well as transitions of care between these settings. Her current research efforts include, but not limited to, re-engineering complex work systems to reduce healthcare-associated infections, improving safe management air flow and aerosol generating procedures in the operating rooms to reduce infection transmission, modeling cognitive and team work to improve diagnostic safety in emergency departments, improving safety care transitions/ handoffs, and improving medication safety among older adults using human-centered design approaches. Her research program has been funded by the CDC, AHRQ, NIH, NSF, multiple foundations and private institutions. Dr. Gurses served as a member of an ad-hoc National Academies Committee on a 2-year effort that produced the 2022 report titled “Frameworks for Protecting Workers and the Public from Inhalation Hazards.” She also served as an Editor/ Scientific Editor for several journals in her field of expertise and currently is an Executive Committee Member of the Human Factors and Ergonomics Society. Dr. Gurses received multiple awards for her contributions to the science of safety, including the Federation of Associations in Behavioral and Brain Sciences Foundation Award, Liberty Mutual Award on Safety, and the International Ergonomics Association Best Paper Award in Occupational Safety and Ergonomics.
In addition to advancing the science of safety, Dr. Gurses’s health care human factors program has had a wide practical impact in the frontline clinical work. For example, when the Ebola epidemic hit in 2014, she led the Armstrong Institute’s efforts in partnering with the CDC to develop a web-based training to prepare health care professionals for potential Ebola cases by integrating human factors and industrial engineering, implementation science, and public health principles and methods with infection control and prevention and clinical expertise. Currently, as part of the CDC’s Project Firstline Initiative, and in collaboration with the JHU Applied Physics Laboratory, Dr. Gurses is leading a large-scale, multidisciplinary, innovative project aimed at improving infection prevention and control in the operating rooms across the nation.

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Presentation Fri, 11 Mar 2022 13:59:39 -0500 2022-03-17T15:00:00-04:00 2022-03-17T16:00:00-04:00 Off Campus Location U-M Industrial & Operations Engineering Presentation Ayse Gurse
Statistics Department Seminar Series: Kean Ming Tan, Assistant Professor, Department of Statistics, University of Michigan (March 18, 2022 10:00am) https://events.umich.edu/event/90170 90170-21668504@events.umich.edu Event Begins: Friday, March 18, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Quantile regression is a powerful tool for learning the relationship between a response variable and a multivariate predictor while exploring heterogeneous effects. However, the non-smooth piecewise linear loss function introduces challenges to the computational aspect when the number of covariates is large. To address the aforementioned challenge, we propose a convolution-type smoothing approach that turns the non-differentiable quantile piecewise linear loss function into a twice- differentiable, globally convex, and locally strongly convex surrogate, which admits a fast and scalable gradient-based algorithm to perform optimization. In the low-dimensional setting, we establish nonasymptotic error bounds for the resulting smoothed estimator. In the high-dimensional setting, we propose the concave regularized smoothed quantile regression estimator, which we solve using a multi-stage convex relaxation algorithm. Theoretically, we characterize both the algorithmic error due to non-convexity and statistical error for the resulting estimator simultaneously. We show that running the multi-stage algorithm for a few iterations will yield an estimator that achieves the oracle property. Our results suggest that the smoothing approach leads to a significant computational gain without a loss in statistical accuracy.

http://www.keanmingtan.com/

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Workshop / Seminar Thu, 10 Mar 2022 11:14:03 -0500 2022-03-18T10:00:00-04:00 2022-03-18T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Kean Ming Tan
LHS Collaboratory (March 22, 2022 12:00pm) https://events.umich.edu/event/90095 90095-21667763@events.umich.edu Event Begins: Tuesday, March 22, 2022 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Presentation 1: PCORNet and the PaTH subnetwork

Kathleen McTigue, MD, MPH, MS

In this talk, Kathleen McTigue describes the vision of PCORNet, its organization, and its value to the field of clinical research. PCORNet is divided into regional subnetworks one of which is PaTH. The organization of PaTH along with its priories will be discussed.

Presentation 2: UM’s site within PCORNet/PaTH

David Williams, PhD

The University of Michigan is an institutional member of PaTH/PCORNet.
In this talk, David Williams describes the organization and processes of the UM site within PCORNet/PaTH, studies in which UM participates, and resources for UM investigators interested in participating in PCORNet studies.

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Lecture / Discussion Wed, 15 Dec 2021 22:38:45 -0500 2022-03-22T12:00:00-04:00 2022-03-22T13:30:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Collaboratory logo
Operationalizing the exposome through chemical surveillance & bioeffect monitoring with high-resolution mass spectrometry (March 22, 2022 12:00pm) https://events.umich.edu/event/93450 93450-21704620@events.umich.edu Event Begins: Tuesday, March 22, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Registration required https://umich.zoom.us/webinar/register/WN_wum4p_pdRMKIixVZJAlicg

Douglas Walker is assistant professor in the Dept of Environmental Medicine & Public Health, Icahn School of Medicine, Mount Sinai. Dr. Walker's research is focused on using untargeted metabolomics to measure environmental exposures, and how exposures lead to biological changes that cause diseases. During his postdoctoral fellowship at Emory University, he acted as Director of Exposome Research for the Clinical Biomarkers Laboratory and was a member of the HERCULES Exposome Research Center. Through application of high-resolution mass spectrometry platforms, Dr. Walker has shown it is possible to provide measures of 10,000-100,000 chemical signals in a cost-effective manner using a single human blood sample, providing a key advance for nutritional assessment, precision medicine and exposome research. At Mount Sinai, his research will be focus on continued development and application of advanced analytical strategies for measuring the occurrence, distribution and magnitude of previously unidentified environmental exposures and assist in delineating the mechanisms underlying environment-related diseases in humans.

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Lecture / Discussion Tue, 15 Mar 2022 13:21:33 -0400 2022-03-22T12:00:00-04:00 2022-03-22T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion Dr. Douglas Walker (Mt. Sinai) presents the M-LEEaD Environmental Research Seminar
PODS Grant Showcase (March 23, 2022 12:00pm) https://events.umich.edu/event/92610 92610-21693587@events.umich.edu Event Begins: Wednesday, March 23, 2022 12:00pm
Location: Weiser Hall
Organized By: Michigan Institute for Data Science

The PODS Grant Showcase will bring together all of the 2021 awarded teams to present on their proposals and the work accomplished so far in the projects. Lightning talks will be given by most teams with deeper dives on certain projects.

Please RSVP if you plan to attend.

Click here for more information about the 2021 PODS Awardees.

Schedule:
- 12:00pm - Light Lunch
- 12:30pm - Introduction, Opening remarks
- 12:36pm - IPODS: Innovative and Powerful Optimization methods for Data science with Statistical guarantees, Albert Berahas (Industrial & Operations Engineering)
- 12:42pm - Supporting decision-making for a vital waterway in the Great lakes by machine learning model-based lake ice forecasting, Ayumi Fujisaki-Manome (CIGLR in SEAS, CLASP)
- 12:48pm - Robust machine learning under distribution shifts and shocks: Application to sustainable air quality, Paramveer Dhillon (School of Information)
- 12:54pm - Data science approach towards a socio-ecological framework for the investigation of continental urban stream water quality pattern, Runzi Wang (School for Environment and Sustainability)
- 1:00pm - Using Geospatial Data Science to Identify Vulnerable Communities to Climate Change, Joshua Newell (School for Environment and Sustainability)
- 1:17pm - Break
- 1:27pm - Ensuring FAIRness in Social Media Archives, Libby Hemphill (School of Information, ICPSR)
- 1:33pm - Images to Integrated Data: Piloting new methods to digitize, parse, and link historical records, Joseph Alexander (ICPSR, Population Studies Center)
- 1:39pm - Measuring Racial Disparity in the Language of Physician-Patient Interactions, David Jurgens (School of Information, Computer Science and Engineering)
- 1:56pm - Classifying the Content of Undergraduate Course-taking at Scale, Kevin Stange (Ford School of Public Policy)
- 2:02pm - Exploring attention-based deep learning methods for improving students’ ability to engage with scientific literature, Kevyn Collins-Thompson (School of Information, Electrical Engineering and Computer Science)
- 2:19pm - Break
- 2:29pm - Coordinated Multi-building Modeling and Management for Flexible Grid Service Innovation, Eunshin Byon (Industrial and Operations Engineering, Civil and Environmental Engineering)
- 2:35pm - Interpretable Machine Learning for Identifying Descriptors of Catalysts for Chemical Conversion, Bryan Goldsmith (Chemical Engineering)
- 2:41pm - Equitable Models for Persistent Opioid Use Prediction and Personalization, Rahul Ladhania (Health Management & Policy, Biostatistics)
- 2:47pm - Machine learning augmented system for continuous fetal monitoring, Kathleen Sienko (Mechanical Engineering)
- 2:53pm - Scientifically-Structured Latent Variable Methods for High-Dimensional Data to Individualize Healthcare, Zhenke Wu (Biostatistics, School of Public Health)
- 3:00pm - End

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Workshop / Seminar Sun, 20 Feb 2022 22:15:17 -0500 2022-03-23T12:00:00-04:00 2022-03-23T15:00:00-04:00 Weiser Hall Michigan Institute for Data Science Workshop / Seminar MIDAS Events
MIPSE Seminar | Plasma Irregularities in the Earth’s Ionosphere and Plasmasphere (March 23, 2022 3:30pm) https://events.umich.edu/event/90467 90467-21671094@events.umich.edu Event Begins: Wednesday, March 23, 2022 3:30pm
Location: Electrical Engineering and Computer Science Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
Plasma irregularities in the ionosphere and plasmasphere can adversely affect space-based communication and navigation systems. Even with research for over 50 years to understand the generation mechanism(s) of these irregularities, uncertainties remain. Plasma irregularities often occur in the post-sunset, ionosphere equatorial F region broadening in altitude over tens of kilometers due to formation of ‘electron clouds with scale sizes of 30 meters’ – equatorial spread F (ESF). Subsequent observational data find ESF to be a complex phenomenon that involves a wide range of spatial and temporal scales: from 10s km to 10s cm and from 10s min to 10s msec producing large-scale electron density ‘bubbles’ or ‘plumes’ that develop in nighttime equatorial ionosphere. We will use the first-principles whole atmosphere models WACCM-X and HIAMCM coupled to the ionosphere/plasmasphere model SAMI3 to investigate the onset and evolution of equatorial spread F on a global scale. The earth’s plasmasphere is a cold, relatively dense plasma on closed magnetic field lines extending from ~ 1000 km to several earth radii. Although this region has often been considered to be quiescent, observations suggest that it is often times structured with plasma ducts. The underlying mechanism(s) to generate these ducts is unclear. Again, we will use WACCM-X and HIAMCM coupled SAMI3 to investigate the development of plasmasphere ducts and longitudinal corrugations in the plasmasphere density.

About the Speaker:
Dr. Joseph Huba is a Vice President at Syntek Technologies. Dr. Huba was at the Naval Research Laboratory as a NRC/NRL post-doc (1975 - 1977), contractor (1977 - 1981), and federal employee (1981 - 2018). He was Head of the Space Plasma Physics Section of the Beam Physics Branch at the Naval Research Laboratory (1995-2018) and Head of the Geophysical and Plasma Dynamics Branch at the Naval Research Laboratory from 1983 until 1989. His current research interests include the study of ionospheric and magnetospheric processes and modeling the earth’s ionosphere/plasmasphere system. He has performed numerous linear and nonlinear studies of a wide variety of plasma instabilities (most notably the lower-hybrid-drift instability). He has written a 3D Hall MHD code (VooDoo) based upon a novel algorithm that he developed to study 2D and 3D Hall magnetic reconnection physics. He has developed (with Dr. G. Joyce) the NRL ionosphere/plasmasphere models SAMI2 and SAMI3 and promoted the SAMI2 Open Source Project. Dr. Huba has over 240 publications in refereed journals in these areas.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for additional information and requirements for in-person and remote attendance: https://mipse.umich.edu/seminars_2122.php

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Lecture / Discussion Thu, 06 Jan 2022 10:41:11 -0500 2022-03-23T15:30:00-04:00 2022-03-23T16:30:00-04:00 Electrical Engineering and Computer Science Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Dr. Joseph Huba
6th Annual RNA Symposium (March 25, 2022 8:00am) https://events.umich.edu/event/93125 93125-21700908@events.umich.edu Event Begins: Friday, March 25, 2022 8:00am
Location: Taubman Biomedical Science Research Building
Organized By: Center for RNA Biomedicine

Symposium Agenda

8:30 / Morning Welcome: President Mary Sue Coleman
8:40 / Jack Szostak "The emergence of RNA from heterogeneous prebiotic chemistry"
9:35 / Gigi Storz "RNA-mediated regulation within protein-coding sequences"
10:30 / coffee break
10:55 / Chris Burge "Impact of RNA-Binding Proteins on Human Genomic Variation"
12:00 / Lunch - please register for free box lunch
1:00 / Afternoon Welcome: Rebecca Cunningham, Vice President for Research
1:10 / Wendy Gilbert “Decoding the untranslated”
2:05 / Michelle Hastings "Splice-Modulating Antisense Oligonucleotides for the Treatment of Disease"
2:55 / Panel discussion with keynote speakers
Topic: Future of RNA Therapeutics, moderated by John Androsavich, Pfizer Global Lead, RNA Medicine

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Lecture / Discussion Wed, 16 Mar 2022 15:43:32 -0400 2022-03-25T08:00:00-04:00 2022-03-25T16:00:00-04:00 Taubman Biomedical Science Research Building Center for RNA Biomedicine Lecture / Discussion 6th Annual RNA Symposium
Statistics Department Seminar Series: Jeff Regier, Assistant Professor, Department of Statistics, University of Michigan (March 25, 2022 10:00am) https://events.umich.edu/event/90171 90171-21668505@events.umich.edu Event Begins: Friday, March 25, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Bayesian statistics provides an elegant formalism for interpreting astronomical images: scientifically interesting but unknown properties of imaged stars and galaxies are treated as latent random variables and pixel intensities are treated as observed random variables. It is challenging, however, to efficiently infer the posterior distribution for realistic Bayesian models of astronomical images. In this talk, I present the Bayesian Light Source Separator (BLISS), which overcomes this challenge through the judicious use of modern variational inference techniques. BLISS embeds a flexible galaxy model that is encoded by a neural network within an interpretable generative model of astronomical images, and employs neural networks, stochastic optimization, and a novel variational bound to facilitate posterior inference. In comparison to a recently published method based on MCMC for detecting astronomical objects in crowded fields, BLISS performs posterior inference 10,000 times faster while achieving substantially higher accuracy.

https://regier.stat.lsa.umich.edu/

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Workshop / Seminar Wed, 16 Mar 2022 12:57:52 -0400 2022-03-25T10:00:00-04:00 2022-03-25T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Jeff Regier
Python Workshop Session 2 - Gurobi (March 29, 2022 3:00pm) https://events.umich.edu/event/93877 93877-21709210@events.umich.edu Event Begins: Tuesday, March 29, 2022 3:00pm
Location: Off Campus Location
Organized By: U-M Industrial & Operations Engineering

> We will be going through how to use Gurobi (optimization solver) and include syntax, tips, and tricks when using it to solve your optimization problems. This is a great tool that can help your classwork and research.
> This is a great session if you understand the basics of Python, but want to learn how to use this powerful optimization solver!!

We kindly ask you install Gurobi prior to the session.

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Workshop / Seminar Wed, 23 Mar 2022 14:58:30 -0400 2022-03-29T15:00:00-04:00 2022-03-29T16:00:00-04:00 Off Campus Location U-M Industrial & Operations Engineering Workshop / Seminar
DCMB / CCMB Weekly Seminar presents Rehan Akbani, PhD (Associate Professor, University of Texas, MD Anderson Cancer Center) (March 30, 2022 4:00pm) https://events.umich.edu/event/93933 93933-21711327@events.umich.edu Event Begins: Wednesday, March 30, 2022 4:00pm
Location: Off Campus Location
Organized By: DCMB Seminar Series

Abstract:

The TP53 tumor suppressor gene is frequently mutated in human cancers. We illustrate the “omics” landscape of the TP53 pathway across five data platforms in 10,225 patient samples from 33 cancers reported by The Cancer Genome Atlas (TCGA). More than 91% of TP53-mutant cancers exhibit second allele loss by mutation, chromosomal deletion, or copy-neutral loss of heterozygosity. TP53 mutations are associated with enhanced chromosomal instability, including increased amplification of oncogenes and deep deletion of tumor suppressor genes. Tumors with TP53 mutations differ from their non-mutated counterparts in RNA, miRNA, and protein expression patterns, with mutant TP53 tumors displaying enhanced expression of cell cycle progression genes and proteins. A mutant TP53 RNA expression signature shows significant correlation with reduced survival in 11 cancer types. Pathway activity scores were computed for all the samples using mRNA expression levels of ten TP53 pathway member genes. Gynecologic cancers show high activity of the pathway. The pathway is correlated with immune infiltration and EMT, and anti-correlated with RTK and RAS/MAPK pathways. In particular, a strong correlation with immune infiltration is observed in breast cancer. ATAC-seq data also show high chromatin accessibility of the pathway genes in breast cancer. Thus, the TP53 pathway has profound effects on tumor cell genomic structure, expression, and clinical outlook depending on tumor type.

Short Bio
Dr. Rehan Akbani is an Associate Professor at the University of Texas MD Anderson Cancer Center in Houston, Texas, in the Department of Bioinformatics and Computational Biology. He has worked at MD Anderson since 2009. He has played many leadership roles in major enterprises, including as PI on TCGA’s MD Anderson Genome Data Analysis Center (GDAC) grant. Within the TCGA consortium, he led four of TCGA’s analysis working groups and he’s been a co-author on each one of TCGA’s 33 marker papers and 27 pan-cancer papers since 2009. His primary contributions have been leading the analysis of proteomics data, and batch effects and quality control of omics data. He won the AACR “Team Science Award” in 2020 for his work in TCGA. He was conferred the “Highly Cited Researchers 2019” award by Web of Science for co-authoring the most highly cited papers in the past decade. He has over 87,700 citations and an h-index of 78 on Google Scholar. In 2014, he won the “Test of Time” award from the European Conference on Machine Learning (ECML) for publishing the most highly cited paper in ECML a decade ago. Currently, Dr. Akbani is the Co-Director of MD Anderson’s proteomics core and Co-Director of the metabolomics core, where he’s led the development of software pipelines for normalizing raw data and generating customer reports semi-automatically. He’s also contributed proteomics data analysis for projects including the Cancer Cell Line Encyclopedia (CCLE) and the MD Anderson Cell Line Project (MCLP).

Host: Veera Baladandayuthapani, Ph.D.
https://umich-health.zoom.us/j/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09

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Lecture / Discussion Thu, 24 Mar 2022 12:32:18 -0400 2022-03-30T16:00:00-04:00 2022-03-30T17:00:00-04:00 Off Campus Location DCMB Seminar Series Lecture / Discussion Rehan Akbani, PhD (Associate Professor, University of TX MD Anderson Cancer Center)
“Bioengineered Synthetic Hydrogels for Regenerative Medicine" (March 31, 2022 12:00pm) https://events.umich.edu/event/92752 92752-21695194@events.umich.edu Event Begins: Thursday, March 31, 2022 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

Andrés J. García is the Executive Director of the Petit Institute for Bioengineering and Bioscience and Regents’ Professor at the Georgia Institute of Technology. Dr. García’s research program integrates innovative engineering, materials science, and cell biology concepts and technologies to create cell-instructive biomaterials for regenerative medicine and generate new knowledge in mechanobiology. This cross-disciplinary effort has resulted in new biomaterial platforms that elicit targeted cellular responses and tissue repair in various biomedical applications, innovative technologies to study and exploit cell adhesive interactions, and new mechanistic insights into the interplay of mechanics and cell biology.

In addition, his research has generated intellectual property and licensing agreements with start-up and multi-national companies. He is a co-founder of 3 start-up companies (CellectCell, CorAmi Therapeutics, iTolerance). He has received several distinctions, including the NSF CAREER Award, Young Investigator Award from the Society for Biomaterials, Georgia Tech’s Outstanding Interdisciplinary Activities Award, the Clemson Award for Basic Science from the Society for Biomaterials, the International Award from the European Society for Biomaterials, and Georgia Tech’s Class of 1934 Distinguished Professor Award.

He is an elected Fellow of Biomaterials Science and Engineering (by the International Union of Societies of Biomaterials Science and Engineering), Fellow of the American Association for the Advancement of Science, Fellow of the American Society of Mechanical Engineers, and Fellow of the American Institute for Medical and Biological Engineering. He served as President for the Society for Biomaterials in 2018-2019. He is an elected member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors.

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Lecture / Discussion Fri, 18 Mar 2022 10:06:32 -0400 2022-03-31T12:00:00-04:00 2022-03-31T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Lecture / Discussion Andrés J. García, Ph.D.
Michael Woodroofe Lecture Series: Peter Bickel, Professor Emeritus, and Professor of the Graduate School, Department of Statistics, University of California, Berkeley (April 1, 2022 10:00am) https://events.umich.edu/event/90172 90172-21668506@events.umich.edu Event Begins: Friday, April 1, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Chatterjee (2019) (see also Dette et al, 2013) introduced a novel rank based measure of dependence between X and Y real, which is 0 iff X and Y are independent, and 1 iff Y=h(X) for some h. Subsequent work by Cao and Bickel (2020) and Shi, Drton and Han (2020) pointed to poor local power properties for testing independence of this statistic as compared to classical procedures, such as those of Spearman, Blum, Kiefer and Rosenblatt and others. In many cases we show that statistics such as Chatteejee’s locally always lead to no power or misleading results. Measuring functional dependence is a different matter and we show, using some of Chatterjee’s ideas, how to construct simple rank based measures which have whatever local power properties we wish for independence testing and point to functional dependence with the same reliability as Chatterjee’s statistic.

Peter Bickel is a Professor Emeritus, and Professor of the Graduate School in the Department of Statistics at University of California, Berkeley. He is past President of the Bernoulli Society and of the Institute of Mathematical Statistics, a MacArthur Fellow, a COPSS prize winner, and a member of the American Academy of Arts and Sciences and of the National Academy of Sciences. He was awarded an honorary Doctorate degree from Hebrew University, Jerusalem in 1986, and from ETH, Zurich in 2014.

https://statistics.berkeley.edu/people/peter-bickel

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Workshop / Seminar Tue, 22 Mar 2022 13:28:51 -0400 2022-04-01T10:00:00-04:00 2022-04-01T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Peter Bickel
Social, Behavioral and Experimental Economics (SBEE) Seminar: Long ties: Formation, social contagion, and economic outcomes (April 4, 2022 11:30am) https://events.umich.edu/event/94240 94240-21726187@events.umich.edu Event Begins: Monday, April 4, 2022 11:30am
Location: North Quad
Organized By: Department of Economics Seminars

Network structure can affect when, where, and how widely new ideas, products, and behaviors are adopted. Classic work in the social sciences has emphasized that "long ties" provide access to novel and advantageous information. In our empirical work, we show how particular life events (migration, education) are associated with forming long ties and how having long ties is associated with beneficial economic outcomes. Counties in the United States with more long ties (and more strong long ties) have higher incomes, lower unemployment, and more economic mobility, even after adjusting for other measures of social connections.
These stylized facts are consistent with some models of contagion. In widely-used models of biological contagion, interventions that randomly rewire edges (generally making them "longer") accelerate spread. However, there are other models relevant to social contagion, such as those motivated by myopic best-response in games with strategic complements, in which individuals adopt if and only if the number of adopting neighbors exceeds a threshold. Recent work has argued that highly clustered, rather than random, networks facilitate spread of these "complex contagions". Here we show that minor modifications to this model, which make it more realistic, reverse this result: we allow very rare below-threshold adoption, i.e., rarely adoption occurs when there is only one adopting neighbor. In a version of "small world" networks, allowing adoptions below threshold to occur with order 1/√n probability — even only along some "short" cycle edges — is enough to ensure that random rewiring accelerates spread. Hypothetical interventions that randomly rewire existing edges or add random edges (versus adding "short", triad-closing edges) in hundreds of empirical social networks reduce time to spread.
In summary, we provide an empirical and theoretical view of the outsized role of long ties in the spread of valuable information and behaviors, even when those behaviors spread via threshold-based contagions.
This is joint work based on two papers: one on threshold-based contagions with Elchanan Mossel, M. Amin Rahimian, Subhabrata Sen, and one on formation of long ties and economic outcomes with Eaman Jahani, Samuel Fraiberger, and Michael Bailey.

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Workshop / Seminar Thu, 31 Mar 2022 14:20:39 -0400 2022-04-04T11:30:00-04:00 2022-04-04T12:45:00-04:00 North Quad Department of Economics Seminars Workshop / Seminar Long ties: Formation, social contagion, and economic outcomes
Environmental Injustice in the Southend of Dearborn (April 5, 2022 12:00pm) https://events.umich.edu/event/93452 93452-21704623@events.umich.edu Event Begins: Tuesday, April 5, 2022 12:00pm
Location: Off Campus Location
Organized By: Michigan Lifestage Environmental Exposures and Disease Center

Registration required https://umich.zoom.us/webinar/register/WN_YhR24FAcQUm3sDY3FZmfwg

The next in the R&R series of talks featuring residents and researchers discussing the environment, health and community is "Environmental Injustice in the Southend of Dearborn".

Panelists include Samra'a Luqman, and environmental activist in the Southend of Dearborn and Zeina Reda, a University of Michigan student. Moderated by Natalie Sampson, Associate Professor of Health and Human Services, University of Michigan-Dearborn.

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Lecture / Discussion Tue, 15 Mar 2022 13:53:19 -0400 2022-04-05T12:00:00-04:00 2022-04-05T12:50:00-04:00 Off Campus Location Michigan Lifestage Environmental Exposures and Disease Center Lecture / Discussion R&R: Residents and Researchers Tuesday Talks at 12 on environment, health, and community
‘Genetic mechanisms of pediatric renovascular hypertension’ (April 5, 2022 4:00pm) https://events.umich.edu/event/91188 91188-21677134@events.umich.edu Event Begins: Tuesday, April 5, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following Cross Talk seminar with:

Dawn Marie Coleman, MD, FACS
Handleman Research Professor Associate Professor, Surgery and Pediatrics & Communicable Diseases
and
Santhi K. Ganesh, MD
Associate Professor, Cardiovascular Medicine,
Department of Internal Medicine, Department of Human Genetics

The Cross Talk is entitled, ‘Genetic mechanisms of pediatric renovascular hypertension.'

Moderator: Filip Bednar, MD, PhD, Surgery

For more information, please email: Organogenesis@umich.edu

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Lecture / Discussion Sun, 20 Mar 2022 16:23:49 -0400 2022-04-05T16:00:00-04:00 2022-04-05T17:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion flyer
Responsible Data Science and AI mini-symposium (April 6, 2022 1:15pm) https://events.umich.edu/event/93987 93987-21713513@events.umich.edu Event Begins: Wednesday, April 6, 2022 1:15pm
Location: Palmer Commons
Organized By: Michigan Institute for Data Science

Data science and AI are having a significant impact on society in uncountable ways, leading to huge benefits in many cases. Yet, increasingly complex analytical pipelines working with poorly understood heterogeneous data sets can give rise to harms in many ways. Furthermore, there could be deleterious systemic effects such as the magnification of disinformation or surveillance capitalism. There has been tremendous recent interest in understanding and managing these concerns.
The Mini-Symposium is a part of the Future Leaders Summit two day event and is open to the public. Below is the event schedule:
1:15 PM - Opening Remarks, Jing Liu (Managing Director, MIDAS, University of Michigan)
1:20 PM - Why Data Scientists Should Care About Data Equity, H.V. Jagadish (Director, MIDAS, University of Michigan)
2:00 PM - Responsible data science is equitable, informed, and secure, David Mongeau (University of Texas San Antonio)
2:40 PM – GeoAI and Spatial Data Science: with Great Power comes Great Responsibility, Shashi Shekhar (University of Minnesota)
3:20 PM - Break
3:40 PM – When Algorithms Trade: Modeling AI in Financial Markets, Michael Wellman (University of Michigan)
4:20 PM – Who Decides What Counts? AI and Big Data: Applications in Economic and Social Science Research, Frauke Kreuter (University of Maryland)
5:00 PM – Panel: Research directions and future breakthroughs, All speakers

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Conference / Symposium Fri, 25 Mar 2022 14:37:52 -0400 2022-04-06T13:15:00-04:00 2022-04-06T17:30:00-04:00 Palmer Commons Michigan Institute for Data Science Conference / Symposium Responsible Data Science and AI Mini Symposium Flyer
Social, Behavioral and Experimental Economics (SBEE) Seminar: Availability of the Gig Economy and Long Run Labor Supply Effects for the Unemployed (April 7, 2022 12:00pm) https://events.umich.edu/event/93557 93557-21705647@events.umich.edu Event Begins: Thursday, April 7, 2022 12:00pm
Location:
Organized By: Department of Economics

A growing number of American workers earn income through platforms in the gig economy which provide access to flexible work (e.g. Uber, Lyft, TaskRabbit). This major labor market innovation presents individuals with a new set of income smoothing opportunities when they lose their job. I use US administrative tax records to measure take up of gig employment following unemployment spells and to evaluate the effect of working in the gig economy on workers' overall labor supply, skill acquisition, and earnings trajectory. To do so, I utilize penetration of gig platforms across counties over time, along with variation in individual-level predicted propensities for gig work based on pre-unemployment characteristics. In the short run, I show an increase in gig work following an unemployment spell and that individuals are correspondingly better able to smooth the resulting drop in income. However, individuals stay in these positions and are less likely to return to traditional wage jobs. Thus, several years later, prime-age (25-54) workers' income lags significantly behind comparable individuals who did not have gig work available. Among older workers (55+), I find an increase in gig work corresponds to a postponement of Social Security retirement benefits and a reduction in receipt of Social Security Disability Insurance (SSDI).

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Workshop / Seminar Wed, 06 Apr 2022 10:54:52 -0400 2022-04-07T12:00:00-04:00 2022-04-07T13:00:00-04:00 Department of Economics Workshop / Seminar Availability of the Gig Economy and Long Run Labor Supply Effects for the Unemployed
Low Back Disorder Causality? (April 7, 2022 3:00pm) https://events.umich.edu/event/92931 92931-21698084@events.umich.edu Event Begins: Thursday, April 7, 2022 3:00pm
Location: Off Campus Location
Organized By: U-M Industrial & Operations Engineering

Seminar Abstract:
Low back disorders (LBDs) are a common world-wide problem that leads to disability, pain and excessive medical costs. While one can find volumes of information relating to the casual pathways associated with LBDs, our rates of LBDs have been increasing over the decades and the treatment costs have increased by over 300 percent in recent years. This situation begs the question: What do we really know about LBD causality? This presentation will review the efforts that have been underway at the Spine Research Institute over the past several decades to unravel the casual pathway puzzle. These efforts involve observational field studies, biomechanical laboratory studies, modeling and more recent attempts to phenotype patients using patient-centered studies. These efforts will be presented as a pattern of evidence to better appreciate the casual pathways associated with LBD that can be used to inform prevention as well as treatment efforts.

Presenter Bio:
William S. Marras, Ph.D.

William S. Marras holds the Honda Chair in Integrated Systems Engineering at the Ohio State University and serves as the Director of the Spine Research Institute at the Ohio State University where he leads NIH, NSF, DoD and privately funded research efforts. Dr. Marras holds joint academic appointments in the Department of Orthopaedic Surgery, the Department of Neurosurgery, and the Department of Physical Medicine & Rehabilitation. His research is focused on understanding multidimensional causal pathways for spine disorders through quantitative epidemiologic evaluations, laboratory biomechanical studies, personalized mathematical modeling, and clinical studies of the lumbar and cervical spines. His findings have been published in over 300 peer-reviewed journal articles, hundreds of refereed proceedings, and numerous books and book chapters including a book entitled The Working Back: A Systems View. Professor Marras has been active in the National Research Council (NRC) having served on over a dozen boards and committees and has served as Chair of the Board on Human Systems Integration for multiple terms. He has also served as Editor-in-Chief of Human Factors and is currently Deputy Editor of Spine. Dr. Marras holds Fellow status in six professional societies and is an elected member of the National Academy of Engineering (the National Academy of Science, Engineering and Medicine), recorded a TEDx talk entitled “Back Pain and your Brain” and has been featured on NPR’s All Things Considered.

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Presentation Fri, 04 Mar 2022 13:32:49 -0500 2022-04-07T15:00:00-04:00 2022-04-07T16:00:00-04:00 Off Campus Location U-M Industrial & Operations Engineering Presentation William Marras
Statistics Department Seminar Series: Alex Belloni, John D. Forsyth Professor of Business Administration, Professor of Decision Sciences and Statistical Science, Fuqua School of Business, Duke University (April 8, 2022 10:00am) https://events.umich.edu/event/90189 90189-21668633@events.umich.edu Event Begins: Friday, April 8, 2022 10:00am
Location: Off Campus Location
Organized By: Department of Statistics

Abstract: In this work we consider bootstrap-based inference methods for functions of the parameter vector in the presence of many moment inequalities where the number of moment inequalities, denoted by p, is possibly much larger than the sample size n. In particular this covers the case of subvector inference, such as the inference on a single component associated with a treatment/policy variable of interest. We consider a min-max of (centered and non-centered) Studentized statistics and study the properties of the associated critical values. In order to establish that we provide a new finite sample analysis that does not rely on Donsker's properties and establish new central limit theorems for the min-max of the components of random matrices. Furthermore, we consider the anti-concentration properties of the min-max of the components of a Gaussian matrix and propose bootstrap based methods to estimate them. In turn this provides a valid data-driven to set the tuning parameters of the bootstrap-based inference methods. Importantly, the tuning parameters generalize choices of literature for Donsker's classes (and showing why those would not be appropriate in our setting) which might better characterize finite sample behavior. This is co-authored with Federico Bugni and Victor Chernozhukov.


https://www.fuqua.duke.edu/faculty/alexandre-belloni

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Workshop / Seminar Mon, 14 Mar 2022 14:45:31 -0400 2022-04-08T10:00:00-04:00 2022-04-08T11:00:00-04:00 Off Campus Location Department of Statistics Workshop / Seminar Alex Belloni
Chaperoning Protein Folding with RNA, and Fun with Foldit (April 8, 2022 12:00pm) https://events.umich.edu/event/94317 94317-21733895@events.umich.edu Event Begins: Friday, April 8, 2022 12:00pm
Location: Chemistry Dow Lab
Organized By: LSA Biophysics

Maintaining the folding health of the proteome is a critical cellular task. It has recently become appreciated that RNAs and RNA:protein complexes play important roles in maintenance of proteomic health. Here, we investigate the role of RNAs in direct modulation of protein aggregation and folding. To begin, an in vitro screen identified that G-quadruplexes are highly efficient general molecular chaperones. Testing these G-quadruplexes in E. coli demonstrated that these RNAs improve the protein folding environment in the cell. Protein folding experiments showed that some G-quadruplexes directly accelerate protein folding. In-cell experiments then found that this acceleration of protein folding drives better quality protein folding in E. coli. Finally, fast protein:RNA oligomerization was discovered for several G-quadruplexes, providing a biophysical explanation for the outsized role of G-quadruplexes in protein aggregation diseases such as Alzheimer’s Disease and ALS. Together, these studies provide a striking example of how RNA structure impacts protein folding and misfolding disease. We will additionally discuss the use of citizen science both to improve structural biology research and biochemistry education using the biochemistry video game Foldit.

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Workshop / Seminar Mon, 04 Apr 2022 08:56:09 -0400 2022-04-08T12:00:00-04:00 2022-04-08T13:00:00-04:00 Chemistry Dow Lab LSA Biophysics Workshop / Seminar Chemistry Dow Lab
2022 CCAT Global Symposium on Connected and Automated Vehicles and Infrastructure (April 12, 2022 8:00am) https://events.umich.edu/event/93055 93055-21700218@events.umich.edu Event Begins: Tuesday, April 12, 2022 8:00am
Location: Michigan Union
Organized By: Center for Connected and Automated Transportation

The 5th annual CCAT Global Symposium returns this year on April 12th and 13th! The conference will be hosted at the Michigan Union in Ann Arbor, MI with both in-person and virtual registration options available to attendees. The two-day, two-track event will continue discussions on cybersecurity, infrastructure, shared mobility, and more.

The 2022 CCAT Global Symposium on Connected and Automated Vehicles and Infrastructure is sponsored by Michigan Engineering, the University of Michigan Transportation Research Institute, and WSP. Women in Autonomy serves as our conference partner.

For complete details and hotel room blocks, please visit the Symposium page on the CCAT website: https://ccat.umtri.umich.edu/symposium/

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Conference / Symposium Mon, 07 Mar 2022 08:14:47 -0500 2022-04-12T08:00:00-04:00 2022-04-12T16:00:00-04:00 Michigan Union Center for Connected and Automated Transportation Conference / Symposium Decorative Image for the 2022 CCAT Global Symposium. It features a 3-D animated city with several forms of transportation and text that reads '2022 Global Symposium' with the CCAT logo in the bottom right.
2022 CCAT Global Symposium on Connected and Automated Vehicles and Infrastructure (April 13, 2022 8:00am) https://events.umich.edu/event/93055 93055-21700219@events.umich.edu Event Begins: Wednesday, April 13, 2022 8:00am
Location: Michigan Union
Organized By: Center for Connected and Automated Transportation

The 5th annual CCAT Global Symposium returns this year on April 12th and 13th! The conference will be hosted at the Michigan Union in Ann Arbor, MI with both in-person and virtual registration options available to attendees. The two-day, two-track event will continue discussions on cybersecurity, infrastructure, shared mobility, and more.

The 2022 CCAT Global Symposium on Connected and Automated Vehicles and Infrastructure is sponsored by Michigan Engineering, the University of Michigan Transportation Research Institute, and WSP. Women in Autonomy serves as our conference partner.

For complete details and hotel room blocks, please visit the Symposium page on the CCAT website: https://ccat.umtri.umich.edu/symposium/

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Conference / Symposium Mon, 07 Mar 2022 08:14:47 -0500 2022-04-13T08:00:00-04:00 2022-04-13T16:00:00-04:00 Michigan Union Center for Connected and Automated Transportation Conference / Symposium Decorative Image for the 2022 CCAT Global Symposium. It features a 3-D animated city with several forms of transportation and text that reads '2022 Global Symposium' with the CCAT logo in the bottom right.
Cellular Mechanisms of Lip and Primary Palate Fusion (April 14, 2022 12:00pm) https://events.umich.edu/event/94366 94366-21735840@events.umich.edu Event Begins: Thursday, April 14, 2022 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

A. Personal Statement

Highlighted publications:

Lewis A.E., Kuwahara A., Franzosi J., Bush, J.O.* (2022) Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Reports, 38(11):110510

Kindberg A.A., Srivastava, V., Muncie, J.M., Weaver V.M., Gartner, Z.J. and Bush, J.O.* (2021). EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts Journal of Cell Biology 220 (6): e202005216 PMCID: PMC8025214

Kuwahara, A., Lewis, A., Coombes, C., Leung, F.S., Percharde M., Bush J.O.* (2020) Delineating the early transcriptional specification of the mammalian trachea and esophagus. eLife, 9:e55526 PMCID: PMC7282815

Niethamer, T. K., Teng, T., Franco, M., Du, Y. X., Percival, C. J., Bush, J.O.* (2020). Aberrant cell segregation in the craniofacial primordium and the emergence of facial dysmorphology in craniofrontonasal syndrome. PLoS Genet. 16, e1008300.

Highlighted projects:
R35 DE031926-01 (PI: Bush) 4/1/2022-3/31/2030
NIH/NIDCR
Signaling control and cellular basis of craniofacial morphogenesis and congenital disease

R01 DE023337 (PI: Bush) 7/9/2013-3/31/2022
NIH/NIDCR
Mechanisms of Eph/Ephrin signaling in craniofacial morphogenesis and craniofrontonasal syndrome

R01DE028753 (PI: Selleri) 4/1/2019-3/31/2024
NIH/NIDCR
Phenotype-driven approach to understanding the function of craniofacial regulators using IMPC-generated mouse strains

UG3DE028872 (PI: Klein) 7/1/2019-6/30/2024
NIH/NIDCR
“Enamel atlas: systems-level amelogenesis tools at multiple scales”

B. Positions, Scientific Appointments and Honors
Positions and Employment:
2019-present Vice Chair, Department of Cell and Tissue Biology
2021-present Professor, Department of Cell and Tissue Biology and Program in Craniofacial Biology, University of California at San Francisco
2017-2021 Associate Professor, Department of Cell and Tissue Biology and Program in Craniofacial
Biology, University of California at San Francisco
2011-2017 Assistant Professor, Department of Cell and Tissue Biology and Program in
Craniofacial Biology, University of California at San Francisco
2005-2011 Postdoctoral research at FHCRC/MSSM
Advisor: Dr. Philippe Soriano
1999-2005 Graduate and postdoctoral research at University of Rochester
Advisor: Dr. Rulang Jiang

Awards and Honors:
2021 Marylou Buyse Distinguished Scientist in Craniofacial Research award from the Society for Craniofacial Genetics and Developmental Biology
2019 F1000 Faculty member for Developmental Biology
2019 David W. Smith workshop on malformations and morphogenesis keynote
2014 American Association of Anatomists Young Faculty Travel Award
2010-present F1000/F1000Prime has featured and highly ranked five of our publications
2010 NIH pathway to independence award from NIH/NIDCR K99/R00 (DE020855)
2006-2008 Ruth L Kirschstein NRSA Individual Fellowship from NIH/NIDCR F32 (DE17506)
2005 Basil Bibby award from the AADR
2004 Michael G. Buonocore award from the AADR

Other Experience and Professional Memberships
2021-2025 Member NIH Skeletal Biology Development and Disease (SBDD)
2021 Cold Spring Harbor Labs Mouse Engineering Course lecturer and workshop leader
2021 American Association of Anatomists Program Committee
2020 Ad hoc reviewer NIH/NIDCR SEP ZDE1 Endogenous Regeneration of Dental, Oral and Craniofacial Tissue
2020 Ad hoc reviewer NIH CSR ZRG1 Fellowships: Cell Biology, Developmental Biology and Bioengineering
2020 Ad hoc reviewer Czech Science Foundation
2019 Ad hoc reviewer for NIH Skeletal Biology Development and Disease (SBDD)
2017 Ad hoc reviewer for NIH on Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing (UG3/UH3) “Tissue Chips and Disease Modeling”
2017-present International Association for Dental Research
2017 Guest Editor, Developmental Biology, special issue on signaling in development
2014 Ad hoc reviewer for NIH on SEP ZRG1 MOSS-D (02), “Bone, Cartilage and Tendon”
2013, 2014 Invited peer reviewer for UK MRC
2012 Ad hoc reviewer for NIH on Council ZES1, “Environmental influences on stem cells in development, health and disease”
2012 Organizer, session chair, Society of Craniofacial Genetics Annual Meeting, San Francisco, CA
2012-present Member, Society for Craniofacial Genetics and Development
2010-present Member, American Association of Anatomists
2000-present Member, Society for Developmental Biology
Ad hoc Reviewer for Development, Developmental Biology, Developmental Dynamics, Journal of Dental Research, Genesis, Immunobiology, Journal of Cell Biology, Science, PLOS Genetics, Immunobiology, PLOS One, Developmental Cell, PLOS Biology, Human Molecular Genetics, JOVE

C. Contributions to Science
1. Identified Eph/ephrin cellular mechanisms in morphogenesis
We have made major contributions to understanding EPH/EPHRIN signaling mechanisms in development in multiple contexts including the craniofacial, neural and neural crest systems. The EPHs compose the largest family of receptor tyrosine kinases in the vertebrate genome constituting one quarter of the total number. Though extensively studied in the nervous system, the signaling mechanisms utilized by this family in other contexts are complex and modestly understood, particularly in vivo. We have learned that a large number of these molecules exhibit distinct expression patterns in the developing craniofacial region. In a novel “conditional-rescue” approach we discovered that EPHRIN-B2 is required in the vascular endothelium for normal NCC development. EPH/EPHRIN signaling is widely known to regulate cellular organization, but the signaling mechanisms by which it does so are unclear. By studying a series of targeted and signaling mutations in EPHRIN-B1 and its receptors EPHB2 and EPHB3 in mice, we determined that EPH/EPHRIN cell segregation involves unidirectional forward signaling from EPHRIN-B1 and relies on kinase activity of the receptors. By live cell imaging we also observe that this unidirectional signaling results in changes in cortical actomyosin accumulation and leading us to interrogate the biophysical basis for EPH/EPHRIN cell segregation. We recently discovered that EPH/EPHRIN signaling modulates the strength of cell-cell contacts by regulating cell interfacial tension through increased heterotypic cortical actomyosin contractility. The minimization of heterotypic interfacial tension also informs how EPH/EPHRIN signaling regulates tissue shape changes relevant to Contributions number 2 and 4. Current efforts in this area focus on how EPH/EPHRIN signaling regulates mesenchymal cell polarity and cell position, forming the basis for part of “Focus one” of this proposal.

Agrawal, P., Wang, M., Kim, S., Lewis, A.E., Bush, J.O.* (2014) The embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate. Developmental Dynamics, 243 (11): 1470-6. PMCID: PMC4404412
Lewis, A.E., Hwa, J., Wang, R., Soriano P., Bush, J.O.* (2015) Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Developmental Biology, 406(2): 186-95. PMCID: PMC4639416
O’Neill, A.O., Kindberg, A.A., Niethamer, T.K. Larson, A.R., Ho, H.H., Greenberg, M.E., Bush, J.O.* (2016) Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. Journal of Cell Biology, 215 (2): 217 PMCID: PMC5984648
Kindberg A.A., Srivastava, V., Muncie, J.M., Weaver V.M., Gartner, Z.J. and Bush, J.O.* (2021). EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts Journal of Cell Biology 220 (6): e202005216 PMCID: PMC8025214

2. Delineated Eph/ephrin signaling mechanisms underlying craniofrontonasal syndrome
We have focused on the role of EPH/EPHRIN signaling in craniofrontonasal syndrome (CFNS), an X-linked condition caused by mutations in EFNB1 characterized by hypertelorism, craniosynostosis, cleft lip and palate, agenesis of the corpus callosum, and particularly increased severity in female patients. By generating a series of signaling mutations in three different gene targeted mouse lines, we were able to determine the relevant modes of signaling for different EPHRIN-B1 phenotypes. We found that reverse signaling by a PDZ-dependent mechanism is critical for axon guidance, whereas it is dispensible for skeletal and craniofacial development. This work showed that different aspects of craniofrontonasal syndrome are caused by loss of function of distinct molecular EPHRIN-B1 signaling functions. Further, by integrating mouse genetics, phosphoproteomic and transcriptomic approaches we have investigated downstream signaling pathways utilized by EPHRIN-B1 in craniofacial development and disease. In this context, we were the first to show that EPH receptor expression is regulated by endocytosis in vivo, and that EPHRIN-B1 controls cell proliferation by the Ras/MAPK signaling pathway. We have also generated an hiPSC model for CFNS, which to our knowledge is the first hiPSC model of a congenital craniofacial syndrome, and used to it ask key questions about the cellular etiology underlying this perplexing disease. Recently, we coupled geometric morphometric techniques with temporal and spatial manipulation of EPHRIN-B1 signaling to elucidate how Efnb1 mutations result in stereotyped dysmorphology in CFNS. Current efforts in this area focus on delineating the proximal signal transduction mechanisms employed by EPH/EPHRIN-B1 signaling in craniofacial morphogenesis using CRISPR/CAS9 based methods.

Bush, J. O. and Soriano, P. (2010). Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev. 24, 2048-60. PMCID: PMC2939368
Niethamer, T.K., Larson, A.R., O’Neill A.K., Bershteyn, M., Hsiao, E.C., Klein, O.D., Pomerantz, J.H., Bush J.O.* (2017) EPHRIN-B1 mosaicism drives cell segregation in craniofrontonasal syndrome hiPSC-derived neuroepithelial cells. Stem Cell Reports, 8(3): 529-537. PMCID: PMC5355632
Niethamer, T. K. and Bush, J. O.* (2019). Getting direction(s): The Eph/ephrin signaling system in cell positioning. Dev. Biol. 447, 42–57.
Niethamer, T. K., Teng, T., Franco, M., Du, Y. X., Percival, C. J., Bush, J. O. (2020). Aberrant cell segregation in the craniofacial primordium and the emergence of facial dysmorphology in craniofrontonasal syndrome. PLoS Genet. 16, e1008300.

3. Developed live imaging approaches to discover cellular mechanisms of craniofacial tissue fusions
Though tissue fusion is a critical final step of lip and palate development, we currently lack cellular resolution understanding of how these tissue fusion events occur, and how they are controlled. We have been examining the cellular and molecular mechanisms by which tissue fusion occurs by combining live imaging of mouse morphogenesis with mouse genetic and physical perturbations. We developed the first successful application of confocal live imaging technology to secondary palate development, and it has allowed us to make new discoveries on the cellular mechanisms at play. Our results indicate that tissue fusion proceeds by a progression of dynamic cell behaviors beginning with convergence of two independent epithelia and concomitant to orthogonal displacement of the resultant shared epithelium. Further, we have found that epithelial cell extrusion, in which cells are squeezed out of an epithelium, is a novel contributor to the removal of the midline epithelial seam (MES). A nearly completed manuscript presents a new live imaging approach to understanding secondary palate fusion, and demonstrates a unique and novel form of collective epithelial migration that is crucial for this process. Most recently, we have also established live imaging approaches for the study of upper lip/primary palate fusion, which we are using to study roles for actomyosin contractility and cell adhesion in this process.

Bush J.O.*, Jiang R.* (2012) Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development. 139(2):231-43. PMCID: PMC3243091
Kim, S., Lewis A.E., Singh V., Ma, X., Adelstein, R., Bush, J.O.,* (2015) Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLOS Biology, 13(4) PMCID: 4388528
Kim S., Prochazka, J., Bush J.O.*, (2017) Live imaging of Mouse Secondary Palate Fusion. JoVE. July 2017 (125) PMCID: In process

4. Improved mouse genetics tools for the study of craniofacial and neural crest development and disease
In the course of our studies, we discovered that the Wnt1-Cre mouse line exhibits developmental phenotypes attributable to elevated and ectopic activation of Wnt signaling. This is a standard and widely used reagent in the fields of craniofacial development and neural crest stem cell biology and our careful analysis of this reagent has already had broad-reaching effects causing labs to re-examine previously published work. To provide a reagent that is devoid of these complications, we generated a Wnt1-Cre2 transgenic mouse line that exhibits the same pattern of activity as Wnt1-Cre but does not cause ectopic activation of Wnt signaling or developmental phenotypes. Over the past five years, I have also served as the faculty advisor for the UCSF mouse inventory database, which facilitates the sharing of genetically modified mouse lines. Most recently, my lab has successfully adopted the iGONAD electroporation method for rapid generation of new mouse lines which we are employing to generate new mouse models for the study of congenital disease.

Lewis, A., Vasudevan, H., O’Neill, A., Soriano, P., Bush, J.O.* (2013) The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Developmental Biology, 379(2):229-34. PMCID: PMC3804302
Wall, E., Scoles, J., Joo, A., Klein, O., Quinonez, C., Bush, J. O., Martin, G. R. and Laird, D. J. (2020). The UCSF Mouse Inventory Database Application, an Open-Source Web App for Sharing Mutant Mice within a Research Community. G3 (Bethesda).

5. Understanding how cell fate and morphogenesis are coupled in the developing foregut
Based initially on phenotypes that we discovered in an Efnb2 mutant mouse line that we generated, we have now established a robust research focus on understanding the specification and morphogenesis of the trachea and esophagus. Classical developmental biology experiments hypothesize that two transcription factors, NKX2.1 and SOX2 act as master regulators of these fates, but this remains untested at the transcriptome level and their targets were unknown. we combine state-of-the-art transcriptomic experiments in embryonic tissues with functional mouse genetic experiments to expose the fundamental process of fate specification of the trachea and esophagus. We performed single cell RNA sequencing in mice to establish a transcriptome-wide understanding of the early steps of trachea and esophagus development and used these data, combined with RNA-sequencing of mutants and embryonic ChIP-seq to interrogate the transcriptome-wide function of NKX2.1 in tracheal and esophageal development. The results of these experiments provide a new understanding of how the trachea and esophagus are initially specified at the genome-wide level. Our studies also reveal that NKX2.1 directly represses Efnb2 to regulate the site of tracheoesophageal separation. These discoveries may be impactful to the study of tracheal, lung, and esophageal developmental biology and related structural anomalies in humans, as well as for the fields of embryonic stem cell biology and for lung and esophageal cancer for which these are keystone transcriptional pathways.

Kuwahara, A., Lewis, A., Coombes, C., Leung, F.S., Percharde M., Bush J.O.* (2020) Delineating the early transcriptional specification of the mammalian trachea and esophagus. eLife, 9:e55526 PMCID: PMC7282815
Lewis A.E., Kuwahara A., Franzosi J., Bush, J.O.* (2022) Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Reports, 38(11):110510

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Lecture / Discussion Tue, 05 Apr 2022 10:39:07 -0400 2022-04-14T12:00:00-04:00 2022-04-14T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Lecture / Discussion Jeffrey Bush Professor and Vice Chair, Department of Cell and Tissue Biology and Program in Craniofacial Biology
Department of Statistics Distinguished Alumni Speaker Series: Dave Hunter, Professor, Department of Statistics, Penn State University (April 15, 2022 10:00am) https://events.umich.edu/event/90173 90173-21668507@events.umich.edu Event Begins: Friday, April 15, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: The 2003 U.S. Supreme Court case known as Gratz v. Bollinger addresses a formula for college admissions that was created by a graduate student in statistics at the University of Michigan for a specific purpose. The method used to create this formula is considered simplistic by modern machine learning standards; yet the debate that ensued, which could not have happened if a more modern approach had been used, illustrates that science and society do not always benefit from machine learning models that achieve the best possible predictive performance. This talk discusses the history of the legal case, the admissions formula and how it was created, and the implications of the debate for how we build predictive models.


David R. Hunter is a Professor of Statistics at Penn State. He earned his Ph.D. in statistics from the University of Michigan in 1999. He has been at Penn State University since 1999, where he is Professor of Statistics and served as head of the Department of Statistics from 2012 to 2018.

Hunter has published widely on statistical models for networks and is a co-creator of the "statnet" suite of packages for network analysis in R. He co-coined the term "MM algorithms" and has written extensively on this and other EM-like algorithms. He has also extended the theory and computational practice of unsupervised clustering using nonparametric finite mixture models.

https://science.psu.edu/stat/people/drh20

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Workshop / Seminar Wed, 13 Apr 2022 19:19:12 -0400 2022-04-15T10:00:00-04:00 2022-04-15T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Dave Hunter
LHS Collaboratory (April 19, 2022 11:00am) https://events.umich.edu/event/93101 93101-21700618@events.umich.edu Event Begins: Tuesday, April 19, 2022 11:00am
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

Presentation 1:
Medical AI - Three Common Myths on the Path from Code to Clinic
Alan Karthikesalingam, MD, PhD
Research Lead, Google Health UK at Google

In this talk, Alan Karthikesalingam will discuss lessons learned in Google's experiences of taking medical AI systems from early research to clinical implementation.

Presentation 2:
Medical AI - Raising the Bar on Evidence Standards
Xiao Liu, MBChB, PhD(link is external)
Ophthalmologist and Clinical Researcher
University Hospitals Birmingham NHS Foundation Trust University of Birmingham, UK

In this talk, Xiao Liu will discuss existing and new clinical evidence standards as applied to medical AI systems. Her talk will focus on recently published standards to ensure transparency and reproducibility of clinical evidence underpinning medical AI systems, including reporting guidelines such as SPIRIT-AI and CONSORT-AI.

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Lecture / Discussion Tue, 08 Mar 2022 00:04:28 -0500 2022-04-19T11:00:00-04:00 2022-04-19T12:30:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion Collaboratory logo
Life, Death and Transformation in the Transition Zone: an Emerging Model of Endochondral Ossification (April 19, 2022 4:00pm) https://events.umich.edu/event/91157 91157-21677016@events.umich.edu Event Begins: Tuesday, April 19, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design is proud to present the following seminar with guest speaker Ralph Marcucio, PhD, Professor, School of Medicine and Director, Laboratory for Skeletal Regeneration Orthopaedic Trauma Institute at University of California, San Francisco.

The talk is entitled, "Life, Death and Transformation in the Transition Zone: an Emerging Model of Endochondral Ossification."

Faculty Host: Kurt Hankenson, PhD, Orthopaedic Surgery

For more information, please email: Organogenesis@umich.edu

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Lecture / Discussion Tue, 12 Apr 2022 10:29:34 -0400 2022-04-19T16:00:00-04:00 2022-04-19T17:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion Flyer
INFORMS Seminar Series: Path to Industry for Ph.D.s (May 3, 2022 5:30pm) https://events.umich.edu/event/94905 94905-21784743@events.umich.edu Event Begins: Tuesday, May 3, 2022 5:30pm
Location: Off Campus Location
Organized By: U-M Industrial & Operations Engineering

During this seminar, you will get to hear from experienced panelists who received their Ph.D. and are now working in diverse industry positions.

The panelists consist of U-M alums Matthew Aguirre, Weiyu Li, Donald Richardson and Anna White. The seminar will be an open discussion, so please come ready with questions and you are welcome to submit questions early when you RSVP.

If you have any additional questions, please contact Lauren Czerniak (czernL@umich.edu)

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Workshop / Seminar Mon, 02 May 2022 08:52:28 -0400 2022-05-03T17:30:00-04:00 2022-05-03T18:30:00-04:00 Off Campus Location U-M Industrial & Operations Engineering Workshop / Seminar
Mike Shapiro, PhD-Variations In Biology Seminar Series (May 10, 2022 4:00pm) https://events.umich.edu/event/87453 87453-21642263@events.umich.edu Event Begins: Tuesday, May 10, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

The Center for Cell Plasticity and Organ Design alongside
The Molecular, Cellular, and Developmental Biology,
Ecology and Evolutionary Biology departments and the
Cell and Molecular Biology CMB/Genetics Training Programs
are proud to present:

Mike Shapiro, PhD
James E. Talmage Presidential Endowed Chair in Biology
Professor, School of Biological Sciences
Adjunct Professor, Department of Human Genetics

Faculty Host: Sundeep Kalantry, PhD, Human Genetics

For more information/questions email: Organogenesis@umich.edu

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Workshop / Seminar Fri, 22 Apr 2022 12:01:42 -0400 2022-05-10T16:00:00-04:00 2022-05-10T17:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Workshop / Seminar flyer
"How To Figure Out What We Actually Know About Communicating Health Numbers: The Methodological Journey (and Some Results) of the Making Numbers Meaningful Project" (May 11, 2022 2:00pm) https://events.umich.edu/event/95028 95028-21788284@events.umich.edu Event Begins: Wednesday, May 11, 2022 2:00pm
Location: Off Campus Location
Organized By: Center for Bioethics and Social Sciences in Medicine (CBSSM)

Numbers are an essential part of many health communications and medical decision making situations. Yet, it is often unclear how best to communicate numbers to patients or the public to achieve different goals. Although there is a large and ever growing literature testing different types of risk and health number communications, both methodological and conceptual differences have made it difficult to summarize the findings from past work. In this seminar, Jessica Ancker (Vanderbilt U.) and Brian Zikmund-Fisher (U. Michigan) will provide an overview and some preliminary findings from their National Library of Medicine-funded R01 award that is systematically reviewing over 400 papers to create evidence-based guidance for health number communication. Drs. Ancker and Zikmund-Fisher will present the conceptual taxonomies from their recently published paper (Risk Analysis, 2022) and discuss how separately considering the specific goals, formats, and structures of health data communications, and the cognitive tasks required of the reader, can lead to clearer insights from the literature. They will then provide an overview of their innovative review methodology, share some of the insights learned from the review so far, and present a preliminary version of the web-based tool that will soon enable health communicators to find the evidence that most pertains to the number communications that they are designing.

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Lecture / Discussion Mon, 09 May 2022 08:29:34 -0400 2022-05-11T14:00:00-04:00 2022-05-11T15:00:00-04:00 Off Campus Location Center for Bioethics and Social Sciences in Medicine (CBSSM) Lecture / Discussion CBSSM May Seminar
EEB Special Seminar: "Insights from phenotype x genotype x environment interactions in species-specific functional traits in non-model systems" (June 2, 2022 2:00pm) https://events.umich.edu/event/95336 95336-21789190@events.umich.edu Event Begins: Thursday, June 2, 2022 2:00pm
Location: Biological Sciences Building
Organized By: Ecology and Evolutionary Biology

ABSTRACT: Untangling the interaction between genotype, environment, and phenotype represents a central goal of evolutionary biology, yet a comprehensive understanding of the relative influence of each remains elusive, especially in non-model systems. My research uses several approaches for investigating the multiple sources of variation that can impact observed phenotypic traits. I highlight how functional traits impacting dispersal ability in Caribbean mangrove species, when coupled with spatially explicit ocean current data, can lead to crucial insights about how genetic variation was shaped by the environment. Especially in periods of rapid climate change, environmental pressures can impact the adaptive nature of traits, and in some cases, adaptive variation can transcend species boundaries. Using a case of recent (i.e., Pleistocene) hybridization in montane sedges, I illustrate how genotype-environment association analyses identify adaptive loci with respect to environmental gradients that overwhelmingly correspond to loci with excess ancestry from one parental lineage. Digitized museum specimens may represent an efficient way to study the interaction of genome, phenome, and environment; I propose an analytical framework for explicitly quantifying the covariation of genomic, phenotypic, and environmental data from thousands of conspecific specimens.

SPEAKER'S WEBSITE: https://richiehodel.com/

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Lecture / Discussion Fri, 27 May 2022 11:19:37 -0400 2022-06-02T14:00:00-04:00 2022-06-02T16:00:00-04:00 Biological Sciences Building Ecology and Evolutionary Biology Lecture / Discussion EEB Special Seminar poster with images of interrelation of environment, phenotype and genotype
“Genetic regulation of epithelial homeostasis and injury” (June 7, 2022 4:00pm) https://events.umich.edu/event/95318 95318-21789154@events.umich.edu Event Begins: Tuesday, June 7, 2022 4:00pm
Location:
Organized By: Center for Cell Plasticity and Organ Design

The NIH T32 Training Program in Organogenesis trainees are please to present a Special Series, "Building and Rebuilding: Regulation of Cell Signaling in Development and Regeneration," featuring guest speaker, Adam D. Gracz, PhD.

Dr. Gracz is an Assistant Professor of Medicine-Division of Digestive Disease at Emory University.

The talk is entitled, “Genetic regulation of epithelial homeostasis
and injury.”

Trainee Host
Megan Radyk, PhD-Lyssiotis & Shah Labs

For more information email: Organogenesis@umich.edu

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Lecture / Discussion Thu, 26 May 2022 10:58:57 -0400 2022-06-07T16:00:00-04:00 2022-06-07T17:00:00-04:00 Center for Cell Plasticity and Organ Design Lecture / Discussion Gracz flyer
Modeling Autonomous Vehicle's Lane Change Decision-Making in Weaving Sections of Freeway Ramps (June 16, 2022 1:00pm) https://events.umich.edu/event/95251 95251-21789065@events.umich.edu Event Begins: Thursday, June 16, 2022 1:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

To date, no systems can recommend when lane changes should be engaged in weaving sections of limited length to ensure that traffic stays safely and smoothly separated. In this presentation, Dr. Lin will describe the naturalistic driving data mining and modeling for the driver’s lane change decision-making in freeway weaving sections. The models were further tested in automated driving with computer simulation and demonstrated in the environment of augmented reality at Mcity. This study could provide valuable insights for developing AV lane change features.

More about this research: https://myumi.ch/j26wj

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About the speakers:
Dr. Brian Lin earned his BS, MS, and Ph.D. in Industrial Engineering from National Tsing Hua University in Taiwan. Dr. Lin has 11 years of experience in automotive human factors research at UMTRI after his Ph.D. His current research is focused on mining naturalistic driving data using statistical and machine-learning methods, driver-assist-system evaluation, driver performance and behavior assessment, and driver distraction and workload mitigation. His most recent work includes human driver’s lane-change maneuvers, drivers’ decisions at intersections, and passengers’ motion discomfort in moving vehicles. Dr. Lin has much experience in conducting experiments to evaluate advanced automotive systems, including auto-braking, lane departure, driver-state monitoring, electronic head units, car-following and curve-assist systems on L2 automation, and lane-change and intersection assist on L3 automation on public roads, test tracks, or simulation. He is familiar with the methods to investigate driver distraction, workload, and human-machine interaction with in-vehicle technologies and safety features. He serves as a peer reviewer for Applied Ergonomics, IEEE Transactions on Intelligent Transportation Systems, IEEE Transactions on Intelligent Vehicles, Transportation Research Part F, and Transportation Research Record.

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Livestream / Virtual Mon, 23 May 2022 12:57:30 -0400 2022-06-16T13:00:00-04:00 2022-06-16T14:00:00-04:00 Off Campus Location Center for Connected and Automated Transportation Livestream / Virtual Promotional Image for the CCAT Research Review with Brian Lin. It features Brian's headshot and a photo of highway traffic.
LHS Collaboratory (June 21, 2022 12:00pm) https://events.umich.edu/event/95245 95245-21789057@events.umich.edu Event Begins: Tuesday, June 21, 2022 12:00pm
Location: Off Campus Location
Organized By: Department of Learning Health Sciences

"Restructuring health systems for learning: Building equity into the Learning Health System"
Learn more about ELSI-LHS (Ethical, Legal, and Social Implications of Learning Health Systems). The session will be moderated by, Jody E. Platt, MPH, PhD, Assistant Professor of Learning Health Sciences.

Speaker:
Lauren A. Taylor, PhD, MDiv, MPH
Assistant Professor
Department of Population Health
Division of Medical Ethics
NYU Grossman School of Medicine

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Lecture / Discussion Wed, 25 May 2022 00:20:49 -0400 2022-06-21T12:00:00-04:00 2022-06-21T13:00:00-04:00 Off Campus Location Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory logo
Certifiable Autonomous Systems Through Online Verification — CCAT Distinguished Lecture Series (July 21, 2022 1:00pm) https://events.umich.edu/event/95889 95889-21791378@events.umich.edu Event Begins: Thursday, July 21, 2022 1:00pm
Location: Off Campus Location
Organized By: Center for Connected and Automated Transportation

Engineers and computer scientists are currently developing autonomous systems whose entire set of behaviors in future, untested situations is unknown. For instance, how can a designer foresee all situations that an autonomous vehicle will face? Keeping in mind that many autonomous systems are safety-critical or operation-critical, it is irresponsible to deploy such systems without testing all possible situations---this, however, seems impossible since even the most important possible situations are often unmanageably many. This presentation proposes a paradigm shift that will make it possible to guarantee safety in unforeseeable situations (under mild model assumptions): Instead of verifying the correctness of a system before deployment, we propose online verification, a new verification paradigm where a system continuously checks the correctness of its next action by itself in its current environment (and only in it) in a just-in-time manner. The usefulness of this method will be demonstrated primarily for autonomous driving and robotics.

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About the speaker: Matthias Althoff received a diploma in Mechatronics and Information Technology from the Department of Mechanical Engineering at the Technical University of Munich, Germany, in 2005. He received his Ph.D. degree in Electrical Engineering from the same university under the supervision of Univ.-Prof. Dr.-Ing./Univ. Tokio Martin Buss in 2010. From 2010 - 2012 he was a postdoctoral researcher at Carnegie Mellon University, USA, with a joint appointment in electrical engineering and the Robotics Institute. He joined the Computer Science Department at Ilmenau University of Technology, Germany, in 2012 as Assistant Professor for Automation Systems. Since 2013 Matthias Althoff is a Professor in Computer Science at the Technical University of Munich.

His research interests include the design and analysis of cyber-physical systems, formal verification of continuous and hybrid systems, reachability analysis, planning algorithms, and robust and fault-tolerant control. The main applications of his research are automated vehicles, robotics, and power systems.

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Livestream / Virtual Thu, 30 Jun 2022 15:30:53 -0400 2022-07-21T13:00:00-04:00 2022-07-21T14:00:00-04:00 Off Campus Location Center for Connected and Automated Transportation Livestream / Virtual Decorative Image for the CCAT Distinguished Lecture Series with Professor Matthias Althoff. It features the presentation title 'Certifiable Autonomous Systems Through Online Verification', Professor Althoff's headshot, and an image of an Autonomous Vehicle.
Workplace Mental Health Conference (Virtual Event) (August 17, 2022 1:00pm) https://events.umich.edu/event/94892 94892-21780195@events.umich.edu Event Begins: Wednesday, August 17, 2022 1:00pm
Location: Off Campus Location
Organized By: Eisenberg Family Depression Center

From the COVID-19 pandemic to ongoing racial injustice—many factors have caused employee expectations of the workplace to evolve. Today, organizations are placing employee well-being at the top of their priorities in order to best support their workforce. This year's conference will provide actionable items employers can take to move the needle on workplace mental health.

This 3rd annual University of Michigan event will bring together key stakeholders to discuss strategies to improve employee mental health. The conference includes presentations and interactive sessions on retention of young employees, the costs of code-switching, burnout, resilience at work, and much more.

What to expect:
-Discover real-world strategies for your workplace
Learn tips to kick-start your workplace mental health initiative
-Hear from well-respected industry and academic experts
-Get your questions answered through interactive Q&A
-Learn from a selection of personal stories, case studies, and panel discussions

Who should join:
-Employers
-C-Suite Leaders
-Health professionals and researchers
-HR professionals
-DEI professionals
-Representatives from diverse industries (public, private, non-profit organizations)
-Anyone with an interest in supporting workplace mental health

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Conference / Symposium Fri, 29 Apr 2022 13:40:44 -0400 2022-08-17T13:00:00-04:00 2022-08-17T17:30:00-04:00 Off Campus Location Eisenberg Family Depression Center Conference / Symposium Join interactive sessions and learn action-oriented strategies to support employee mental health.
Traffic Signal Control via Decentralized Decomposition Approaches (August 24, 2022 1:00pm) https://events.umich.edu/event/96271 96271-21792217@events.umich.edu Event Begins: Wednesday, August 24, 2022 1:00pm
Location:
Organized By: Center for Connected and Automated Transportation

Traffic congestion is a global pressing issue that can be mitigated via effective traffic signal control schemes. In this presentation, based on a cell transmission model, the team from the University of Michigan coordinated the control of traffic signals at multiple intersections to maximize vehicle throughput on corridors or road networks under uncertain traffic demand and vehicle turning. They formulated a two-stage, stochastic mixed-integer linear program using finite samples of the uncertain parameter, and combined Benders decomposition with the alternating direction method of multipliers to develop spatially-temporally distributed algorithms for optimizing the problem. They then tested instances of traffic signal control on corridors and grid networks, based on synthetic and real-world traffic data. The results show that

1. considering traffic uncertainty can significantly improve the signal control quality and
2. decentralized decomposition approaches can quickly find high-quality signal plans for multiple intersections in complex road networks, and fully utilize the computation and communication technologies in smart-transportation infrastructures.
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About the speaker: Siqian Shen is an Associate Professor and Richard Wilson Faculty Scholar in the Department of Industrial and Operations Engineering at the University of Michigan. She also serves as the Associate Director at the Michigan Institute for Computational Discovery & Engineering (MICDE). She obtained a B.S. degree from Tsinghua University in 2007 and Ph.D. from the University of Florida in 2011. Her theoretical research interests are in integer programming, stochastic/robust optimization, and network optimization. Applications include optimization and risk analysis of energy, healthcare, cloud computing, and transportation systems. She is a recipient of the IIE Pritsker Doctoral Dissertation Award, IBM Smarter Planet Innovation Faculty Award, and Department of Energy (DoE) Early Career Award.

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Presentation Wed, 27 Jul 2022 12:31:10 -0400 2022-08-24T13:00:00-04:00 2022-08-24T14:00:00-04:00 Center for Connected and Automated Transportation Presentation Decorative Image for the CCAT Research Review with Dr. Siqian Shen. It includes a picture of a traffic control light, the presentation title "Traffic Signal Control Via Decentralized Decomposition Approaches", and a headshot of the Professor.
Statistics Department Seminar Series: Yuekai Sun, Assistant Professor, Department of Statistics, University of Michigan (September 9, 2022 10:00am) https://events.umich.edu/event/97646 97646-21794844@events.umich.edu Event Begins: Friday, September 9, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: Many instances of algorithmic bias are caused by distribution shifts, but most algorithmic fairness practices were not developed with distribution shifts in mind. This discrepancy between the causes of algorithmic biases and the premise of prior work on algorithmic fairness leads us to study whether enforcing fairness mitigates algorithmic biases caused by distribution shifts. On one hand, we show that there are scenarios in which enforcing fairness does not improve model performance. In fact, it may even harm performance. On the other hand, we derive sufficient conditions under which enforcing group and individual fairness successfully mitigates algorithmic biases due to distribution shifts.


Yuekai Sun is an assistant professor in the statistics department at the University of Michigan. His research is guided by the statistical and computational challenges in machine learning. Some topics of recent interest are algorithmic fairness, transfer learning, and federated learning.

https://yuekai.github.io/

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Workshop / Seminar Mon, 29 Aug 2022 14:42:09 -0400 2022-09-09T10:00:00-04:00 2022-09-09T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Yuekai Sun
The Productivity of Professions: Evidence from the Emergency Department (September 12, 2022 4:00pm) https://events.umich.edu/event/97245 97245-21794177@events.umich.edu Event Begins: Monday, September 12, 2022 4:00pm
Location: Ross School of Business
Organized By: Department of Economics

Professions play a key role in determining the division of labor and the returns to work. This paper studies the productivity difference between two distinct professions performing overlapping tasks—physicians and nurse practitioners (NPs)—but with stark differences in background, training, and pay. Using data from the Veterans Health Administration and quasi-experimental variation in patient probability of being treated by physicians versus NPs in the emergency department, we find that, compared to physicians, NPs significantly increase patient length of stay (by 11 percent) and medical costs (by 7 percent). Despite higher medical resource use, NPs achieve less favorable patient outcomes: They increase patient 30- day preventable hospitalization rate by 20 percent. We find evidence suggesting channels related to lower human capital among NPs relative to physicians. Our estimates suggest a net increase in medical costs with the use of NPs, even when accounting for NP salaries that are half as much as physician salaries. Despite large productivity differences between professions, we find even larger productivity differences within professions and substantial productivity overlap between professions. We find little overlap in wages between NPs and physicians and, within professions, no significant correlation between productivity and wages.

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Workshop / Seminar Tue, 23 Aug 2022 10:39:15 -0400 2022-09-12T16:00:00-04:00 2022-09-12T17:20:00-04:00 Ross School of Business Department of Economics Workshop / Seminar The Productivity of Professions: Evidence from the Emergency Department
IOE 813 Seminar Series (September 12, 2022 4:30pm) https://events.umich.edu/event/98304 98304-21796465@events.umich.edu Event Begins: Monday, September 12, 2022 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: U-M Industrial & Operations Engineering

Speaker: Amy Cohn, PhD, U-M IOE, CHEPS, MM

Description: There are many similarities between airline and healthcare systems. Both exhibit tremendous complexity, dependence on expensive and constrained resources, reliance on a highly‐trained workforce, a direct connection from quality to safety, and a significant and immediate impact on the lives of a vast population of individuals. In this talk, I will draw parallels between healthcare and passenger aviation, identifying areas, where lessons learned in one, can be applied to the other, as well as highlighting critical differences that must be considered when attempting to transfer knowledge from one domain to the other.

Bio: Dr. Amy Cohn is an Arthur F. Thurnau Professor in the Department of Industrial and Operations Engineering at the University of Michigan, where she also holds an appointment in the Department of Health Management and Policy in the School of Public Health. Dr. Cohn is the Faculty Director of the Center for Healthcare Engineering and PaƟent Safety (CHEPS) and the Chief Transformation Officer at Michigan Medicine. She holds an A.B. in applied mathematics, magna cum laude, from Harvard University and a PhD in operaƟons research from the Massachusetts institute of Technology. Her primary research interest is in the application of operaƟons research tools to solving operational problems in healthcare, including paƟent access, staff scheduling, and provider wellness. She values teaching, mentoring, having a positive impact on society through her work, and helping to foster a vibrant, diverse, nurturing community of scholars. She and her husband Jonathan are the proud parents of two sons, Tommy and Peter.

The seminar series “Providing Better Healthcare through Systems Engineering” is presented by the U‐M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi‐disciplinary, systems‐engineering approach.

For the Zoom link and password, and to be added to the weekly e‐mail for the series, please RSVP or contact genehkim@umich.edu

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Workshop / Seminar Thu, 08 Sep 2022 11:09:11 -0400 2022-09-12T16:30:00-04:00 2022-09-12T17:30:00-04:00 Industrial and Operations Engineering Building U-M Industrial & Operations Engineering Workshop / Seminar Amy Cohn
MIPSE Seminar | Turbulence and Transport Research Beyond the Burning Plasma Era (September 14, 2022 1:30pm) https://events.umich.edu/event/97908 97908-21795308@events.umich.edu Event Begins: Wednesday, September 14, 2022 1:30pm
Location: Herbert H. Dow Building
Organized By: Michigan Institute for Plasma Science and Engineering (MIPSE)

Abstract:
The prospect of near-term fusion electricity opens new doors for university-based plasma physics research. Even after the grand societal challenge of putting fusion on the grid is achieved, research addressing grand intellectual challenges in plasma transport will remain vibrant. University groups will engage with sponsors and collaborators including not only governments and national labs around the world, but also private companies and utilities. In this talk I present side-by-side examples of recent research results on turbulence and transport measurements, as well as predictive simulation and modeling, carried out by researchers at MIT in support of both the nascent fusion industry and the established fission industry. I will share my perspective, as an academic department head, on the future of fusion research in universities as we move through and beyond the era of burning plasmas.

About the Speaker:
Anne E. White is the head of the Nuclear Science and Engineering Department at MIT and MIT School of Engineering Distinguished Professor of Engineering. She received her PhD in experimental plasma physics in 2008 from UCLA and was a DOE Fusion Energy Sciences ORISE post-doctoral fellow before becoming an assistant professor at MIT in 2009. White performs fusion energy research at the Plasma Science and Fusion Center (PSFC) at MIT and in involved in research collaborations at tokamaks in the US and around the world. Prof. White is active in the fusion community, is a member of American Physical Society and American Nuclear Society, and has served on the executive committees and program committees of many workshops and conferences. She currently serves on the US DOE Fusion Energy Sciences Advisory Committee (FESAC). She has won numerous awards for her research, teaching and service to MIT and to the fusion community, and is an APS Fellow.

The seminar will be conducted in person and simulcast via Zoom; it is free and open to the public. Please check the MIPSE website for information about in-person and remote attendance: https://mipse.umich.edu/seminars_2223.php.

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Lecture / Discussion Thu, 01 Sep 2022 10:13:50 -0400 2022-09-14T13:30:00-04:00 2022-09-14T14:30:00-04:00 Herbert H. Dow Building Michigan Institute for Plasma Science and Engineering (MIPSE) Lecture / Discussion Prof. Anne White
Using Annoto with Video Content (September 15, 2022 10:00am) https://events.umich.edu/event/98158 98158-21795658@events.umich.edu Event Begins: Thursday, September 15, 2022 10:00am
Location: Off Campus Location
Organized By: Information and Technology Services (ITS)

ABOUT THIS WORKSHOP

Canvas Workshop

Workshop Agenda: * Background * Product Overview * In-Video discussion widget * Insights Dashboard * Kaltura & Canvas Support * Product Demonstration * Hands-on experience * Customer Use Cases * Value proposition and Key Impacts * Q&A

- Annoto is available as free trial tool for Fall 2022.
- Annoto provides in-video discussion tools in Canvas and is used within MiVideo/Kaltura.
Watch a two-minute video demo of Annoto. [https://youtu.be/1T9EZi7KJcc]
- Annoto enables your course participants to add time-based annotations as an overlay to any video content, turning passive video watching into an active and collaborative learning experience, while providing you actionable insights on the students and the video content delivered.
- Annoto covers all your different use cases when using video content and is used for student assignments, skills development, collaborative learning, guided watching, peer review, and many more.

Level: Beginner
Trainer: Gili Cohen

The ITS Teaching Online Technique Training Workshops are available to help you prepare for teaching online, in person, hybrid, or HyFlex.

Find detailed training information on this and additional workshops, including on-demand recordings, on the ITS Training website: https://its.umich.edu/training/canvas

Join all ITS training sessions in this series via the following Zoom URL for all workshops: https://umich.zoom.us/j/96810579762

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Workshop / Seminar Tue, 06 Sep 2022 16:46:11 -0400 2022-09-15T10:00:00-04:00 2022-09-15T11:30:00-04:00 Off Campus Location Information and Technology Services (ITS) Workshop / Seminar Using Annoto with Video Content
Navigation Pain: Drip Pricing and Personalization in Two-Sided Digital Markets (September 16, 2022 10:00am) https://events.umich.edu/event/98792 98792-21797189@events.umich.edu Event Begins: Friday, September 16, 2022 10:00am
Location: Lorch Hall
Organized By: Department of Economics

This paper considers two critical issues of platform design: personalized recommendations and drip pricing. In many online markets, consumers often have little ex-ante knowledge of product features. In these markets, how does platform design impact consumer welfare, seller outcomes, and platform profits? I answer this question in the context of the online market for hotel rooms using data from Expedia Group, an online travel agency (OTA). I present evidence that in this market, consumers do not ex-ante know product features, including price. On the demand side, this paper proposes an optimal sequential search model where consumers have rational expectations of the joint distribution of product features, form consideration sets through page turns and clicks, and make a final purchase decision from their consideration set. As for the platform, I use LambdaMART, a machine learning algorithm, to create a mirror of the platform’s recommendation system. The search engine mirror allows for the supply side model where profit-maximizing firms consider how changes in price impact position on the page in search results. The proposed model and estimation strategies allow for platform design counterfactuals, including changes to the order of search results and feature emphasis. The paper concludes by evaluating the welfare effects of personalized recommendations and drip pricing.

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Workshop / Seminar Mon, 19 Sep 2022 11:01:32 -0400 2022-09-16T10:00:00-04:00 2022-09-16T11:20:00-04:00 Lorch Hall Department of Economics Workshop / Seminar Navigation Pain: Drip Pricing and Personalization in Two-Sided Digital Markets
Statistics Department Seminar Series: Patrick Flaherty, Associate Professor, Department of Mathematics and Statistics, University of Massachusetts, Amherst (September 16, 2022 10:00am) https://events.umich.edu/event/97647 97647-21794845@events.umich.edu Event Begins: Friday, September 16, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: We consider the problem of sequential multiple hypothesis testing with nontrivial data collection cost. This problem appears, for example, when conducting biological experiments to identify differentially expressed genes in a disease process. This work builds on the generalized alpha-investing framework that enables control of the false discovery rate in a sequential testing setting. We make a theoretical analysis of the long-term asymptotic behavior of alpha-wealth which motivates a consideration of sample size in the alpha-investing decision rule. Using the game theoretic principle of indifference, we construct a decision rule that optimizes the expected return (ERO) of alpha-wealth and provides an optimal sample size for the test. We show empirical results that a cost-aware ERO decision rule correctly rejects more false null hypotheses than other methods. We extend cost-aware ERO investing to finite-horizon testing which enables the decision rule to hedge against the risk of unproductive tests. Finally, empirical tests on a real data set from a biological experiment show that cost-aware ERO produces actionable decisions as to which tests to conduct and if so at what sample size.

Patrick Flaherty is an Associate Professor in the Department of Mathematics and Statistics at the University of Massachusetts, Amherst. His research includes large-scale genomic data, hierarchical Bayesian models, variational inference, robust experiment design.

https://www.math.umass.edu/directory/faculty/patrick-flaherty

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Workshop / Seminar Mon, 12 Sep 2022 15:49:31 -0400 2022-09-16T10:00:00-04:00 2022-09-16T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Patrick Flaherty
IOE 101 Career Seminar Series: Applied Safety (September 16, 2022 12:00pm) https://events.umich.edu/event/97904 97904-21795708@events.umich.edu Event Begins: Friday, September 16, 2022 12:00pm
Location: Industrial and Operations Engineering Building
Organized By: U-M Industrial & Operations Engineering

Bio: Mr. Frantz is a Certified Human Factors Professional specializing in human factors/ergonomics, warnings, and product, occupational, and premises safety. He holds a B.S.E. and M.S.E. from the University of Michigan in Industrial and Operations Engineering and continuing product safety training through St. Louis University.
Mr. Frantz teaches a safety management course in the College of Engineering at the University of Michigan. His research and teaching include product and occupational safety, risk assessment and communication, human factors in accident causation, and assessment of walking surfaces.

Mr. Frantz has extensive experience developing and evaluating warnings and safety symbols for a wide variety of consumer and commercial products. He has been involved in the development of national standards for product warnings. He is a member of the American National Standards Institute (ANSI) Z535.4 Subcommittee on Product Safety Signs and Labels and Z535.7 Subcommittee on Product Safety Information in Electronic Media.

This seminar series exposes students to a wide-ranging of potential careers in industrial and operations engineering such as consulting, data science, healthcare, finance, supply chain management, energy, transportation, and others. Students will learn from industry affiliates about the nature of different careers and how to prepare for success after graduation.

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Workshop / Seminar Wed, 07 Sep 2022 09:13:30 -0400 2022-09-16T12:00:00-04:00 2022-09-16T13:00:00-04:00 Industrial and Operations Engineering Building U-M Industrial & Operations Engineering Workshop / Seminar Jared Frantz
Opiates of the Masses? Deaths of Despair and the Decline of American Religion (September 19, 2022 4:00pm) https://events.umich.edu/event/97247 97247-21794193@events.umich.edu Event Begins: Monday, September 19, 2022 4:00pm
Location: Ross School of Business
Organized By: Department of Economics

In recent decades, death rates from poisonings, suicides, and alcoholic liver disease have dramatically increased in the United States. We show that these “deaths of despair” began to increase relative to trend in the early 1990s, that this increase was preceded by a decline in religious participation, and that both trends were driven by middle-aged white Americans. Using repeals of blue laws as an exogenous shock to religiosity, we confirm that religious practice has significant effects on these mortality rates. Our findings show that social factors such as organized religion can play an important role in understanding deaths of despair.

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Workshop / Seminar Tue, 23 Aug 2022 10:48:46 -0400 2022-09-19T16:00:00-04:00 2022-09-19T17:20:00-04:00 Ross School of Business Department of Economics Workshop / Seminar Opiates of the Masses? Deaths of Despair and the Decline of American Religion
IOE 813 Seminar Series (September 19, 2022 4:30pm) https://events.umich.edu/event/98312 98312-21796477@events.umich.edu Event Begins: Monday, September 19, 2022 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: U-M Industrial & Operations Engineering

Speaker: Siqian Shen, PhD, U-M IOE, MICDE

Description: The outbreak of coronavirus disease 2019 (COVID‐19) has created a global health crisis and the response to the COVID‐19 pandemic is deeply influenced by local, national, and global policies and decisions. In this talk, we present a few examples to demonstrate (i) how infection status dynamically affects mobility patterns and travel behavior, (ii) how to strategize and dynamically perform lockdown and reopening, and (iii) how to redesign public transit systems to reduce passengers’ infection risk. In particular, we show the use of data analytics tools and optimization models for solving these problems, validated using real data of COVID‐19 infection, business economy, and local mobility.

Bio: Siqian Shen is an Associate Professor and Richard Wilson Faculty Scholar in the Department of Industrial and OperaƟons Engineering at the University of Michigan. She also serves Associate Director in the Michigan Institute for Computational Discovery & Engineering (MICDE). She obtained a B.S. degree from Tsinghua University in 2007 and Ph.D. from the University of Florida in 2011. Her theoretical research interests are in integer programming, stochastic/robust optimization, and network optimization. Applications include optimization and risk analysis of energy, healthcare, cloud computing, and transportation systems. She is a recipient of the IIE Pritsker Doctoral Dissertation Award, IBM Smarter Planet Innovation Faculty Award, and Department of Energy (DoE) Early Career Award.

The seminar series “Providing Better Healthcare through Systems Engineering” is presented by the U‐M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi‐disciplinary, systems‐engineering approach.

For the Zoom link and password, and to be added to the weekly e‐mail for the series, please RSVP or contact genehkim@umich.edu

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Workshop / Seminar Thu, 08 Sep 2022 11:18:21 -0400 2022-09-19T16:30:00-04:00 2022-09-19T17:30:00-04:00 Industrial and Operations Engineering Building U-M Industrial & Operations Engineering Workshop / Seminar Siqian Shen
CPOD Seminar Talk: Brian Capell, MD, PhD, (UPenn) Chromatin at the nexus of epithelial development, differentiation, and cancer (September 20, 2022 4:00pm) https://events.umich.edu/event/98510 98510-21796732@events.umich.edu Event Begins: Tuesday, September 20, 2022 4:00pm
Location: Off Campus Location
Organized By: Center for Cell Plasticity and Organ Design

Center for Cell Plasticity and Organ Design with UM-Skin Biology and Disease Resource based Center presents:

Brian Capell, MD, PhD
University of Pennsylvania
Chromatin at the nexus of epithelial development, differentiation, and cancer
In-Person: BSRB ABC Seminar Rooms
Zoom Meeting Option ID: 932 944 30678

Faculty Host: Rajesh Rao, MD
Leonard G. Miller Professor of Ophthalmology and Visual Sciences

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Lecture / Discussion Mon, 12 Sep 2022 11:52:11 -0400 2022-09-20T16:00:00-04:00 2022-09-20T17:00:00-04:00 Off Campus Location Center for Cell Plasticity and Organ Design Lecture / Discussion Capell
DCMB Weekly Seminar (September 21, 2022 4:00pm) https://events.umich.edu/event/98815 98815-21797218@events.umich.edu Event Begins: Wednesday, September 21, 2022 4:00pm
Location: Palmer Commons
Organized By: DCMB Seminar Series

Abstract:
The intersect between the life sciences (cells, tissues, organs) and engineered materials (polymers, biomacromolecules, semiconductors) is crucial for a wide range of medical and biotechnological applications. Hence, the precise control of biotic/abiotic interfaces has been one of the main obstacles of past decades. The Lahann Lab designs polymers for a range of different medical applications. In particular, we have developed a class of protein nanoparticles for targeting of glioblastoma. In addition, I will summarize our efforts related to sheet-like 3D organoid systems and will address recent advances with morphologically designed interfaces.

Research Interests:
Designer surfaces, advanced polymers, biomimetic materials, microfluidic devices, engineered microenvironments, nano-scale self-assembly.

Joerg Lahann’s research is broadly related to surface engineering with strong ties to biomedical engineering and nanotechnology. His research on reversibly switching surfaces was featured in an article in Science (J. Lahann, et al., A Reversibly Switching Surface, January 17, 2003, 299, 371-374.) These “smart surfaces” can reversibly switch properties in response to an external stimulus. To demonstrate these findings, a surface design was developed that can be changed from water-attracting to water-repelling with the application of a weak electric field. Designed as a switch, single-layered molecular-level machines are aligned on a surface using self-assembly and then are flipped between defined microscopic states. This type of surface design may offer a new paradigm for interfacial engineering as it amplifies reversible conformational transitions at a molecular level to macroscopic changes in surface properties without altering the chemical identity of the surface.

Joerg has also developed a novel class of polymers with potential for biomimetic and spatially directed surface engineering. This “reactive coating” technology uses chemical vapor deposition (CVD) polymerization to deposit a wide range of chemical signatures on various substrate materials. Its simplicity in providing chemically reactive groups and its applicability to three-dimensional geometries (e.g., for microfluidics) enables the exact tailoring of surface properties and the preparation of biologically relevant microenvironments. Reactive coatings are compatible with soft lithographic processes, allowing for patterning of proteins, DNA, cytokines, and mammalian cells.

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Lecture / Discussion Thu, 15 Sep 2022 11:36:52 -0400 2022-09-21T16:00:00-04:00 2022-09-21T17:00:00-04:00 Palmer Commons DCMB Seminar Series Lecture / Discussion (Protein pattern deposited on a polymer surface, artistic rendering, credit: Bahar Dadfar)
LHS Collaboratory (September 22, 2022 12:00pm) https://events.umich.edu/event/96027 96027-21791723@events.umich.edu Event Begins: Thursday, September 22, 2022 12:00pm
Location: Palmer Commons
Organized By: Department of Learning Health Sciences

LHS Collaboratory Kickoff Poster Session Showcasing LHS Work at the University of Michigan

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Lecture / Discussion Tue, 12 Jul 2022 10:55:57 -0400 2022-09-22T12:00:00-04:00 2022-09-22T14:00:00-04:00 Palmer Commons Department of Learning Health Sciences Lecture / Discussion LHS Collaboratory logo
OHS Seminar Series Schedule (September 22, 2022 12:00pm) https://events.umich.edu/event/98131 98131-21795615@events.umich.edu Event Begins: Thursday, September 22, 2022 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

OHS Seminar Series Schedule Fall 2022 - Stay tuned for more updates!

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Presentation Tue, 06 Sep 2022 13:16:28 -0400 2022-09-22T12:00:00-04:00 2022-09-22T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Presentation OHS Seminar Series Schedule Fall 2022
Postdoc Appreciation Week – Special Presentations (September 22, 2022 12:00pm) https://events.umich.edu/event/98318 98318-21796492@events.umich.edu Event Begins: Thursday, September 22, 2022 12:00pm
Location: Dental & W.K. Kellogg Institute
Organized By: Office of Research School of Dentistry

Felicia Miranda, DDS, MS, PhD
Postdoctoral Fellow
Department of Orthodontics
University of Michigan School of Dentistry
Mentor: Lucia Cevidanes

Amanda Rodriguez, DDS, MS
Research Fellow & PiMA Program Assistant Director
Department of Periodontics and Oral Medicine
University of Michigan School of Dentistry
Mentors: Drs. Hsun-Liang Chan, DDS, MS and
Oliver Kripfgans, PhD

Hiroki Ueharu, Ph.D.
Department of Biologic & Materials Sciences and Prosthodontics, University of Michigan School of Dentistry
Mentor: Dr. Yuji Mishina

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Presentation Thu, 08 Sep 2022 12:20:48 -0400 2022-09-22T12:00:00-04:00 2022-09-22T13:00:00-04:00 Dental & W.K. Kellogg Institute Office of Research School of Dentistry Presentation Postdoc Appreciation Week – Special Presentations
Departmental Seminar (899): Frank Curtis (September 22, 2022 3:00pm) https://events.umich.edu/event/96923 96923-21793572@events.umich.edu Event Begins: Thursday, September 22, 2022 3:00pm
Location: Industrial and Operations Engineering Building
Organized By: U-M Industrial & Operations Engineering

Speaker: Frank Curtis, Professor at Lehigh University

Title: "Deterministically Constrained Stochastic Optimization"

Abstract: Curtis will present the recent work by his research group on the design, analysis, and implementation of algorithms for solving continuous nonlinear optimization problems that involve a stochastic objective function and deterministic constraints. The talk will focus on sequential quadratic optimization (commonly known as SQP) methods for cases when the constraints are defined by nonlinear systems of equations and inequalities. These methods are applicable for solving various types of problems, such as for training machine learning (e.g., deep learning) models with constraints. His work focuses on the "fully stochastic" regime in which only stochastic gradient estimates are employed, for which we have derived convergence-in-expectation results and worst-case iteration complexity bounds that are on par with stochastic gradient methods for the unconstrained setting. Curtis will also discuss the various extensions that his group is exploring.

Bio: Frank E. Curtis is a Professor in the Department of Industrial and Systems Engineering at Lehigh University. Prior to joining Lehigh, he received his bachelor's degree from the College of William and Mary, received his master's and doctoral degrees from the Department of Industrial Engineering and Management Science at Northwestern University, and worked as a Postdoctoral Researcher in the Courant Institute of Mathematical Sciences at New York University. His research focuses on the design, analysis, and implementation of numerical methods for solving large-scale nonlinear optimization problems. He received an Early Career Award from the Advanced Scientific Computing Research program of the U.S. Department of Energy, and has had other funded projects with the U.S. National Science Foundation, Office of Naval Research, and Advanced Research Projects Agency - Energy. He received, along with Leon Bottou (Facebook AI Research) and Jorge Nocedal (Northwestern), the 2021 SIAM/MOS Lagrange Prize in Continuous Optimization. He was awarded, with James V. Burke (U. of Washington), Adrian Lewis (Cornell), and Michael Overton (NYU), the 2018 INFORMS Computing Society Prize. He and team members Daniel Molzahn (Georgia Tech), Andreas Waechter (Northwestern), Ermin Wei (Northwestern), and Elizabeth Wong (UC San Diego) were awarded second place in the ARPA-E Grid Optimization Competition in 2020. He currently serves as an Associate Editor for Mathematical Programming, SIAM Journal on Optimization, Mathematics of Operations Research, IMA Journal of Numerical Analysis, and Mathematical Programming Computation. He previously served as the Vice Chair for Nonlinear Programming for the INFORMS Optimization Society and is currently very active in professional societies and groups related to mathematical optimization, including INFORMS, the Mathematics Optimization Society, and the SIAM Activity Group on Optimization.

The Departmental Seminar Series is open to all. U-M Industrial and Operations Engineering graduate students and faculty are especially encouraged to attend. There will be a reception to follow the seminar in the IOE commons from 4 -5 p.m

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Workshop / Seminar Mon, 19 Sep 2022 11:55:34 -0400 2022-09-22T15:00:00-04:00 2022-09-22T16:00:00-04:00 Industrial and Operations Engineering Building U-M Industrial & Operations Engineering Workshop / Seminar Hacker binary attack code. Made with Canon 5d Mark III and analog vintage lens, Leica APO Macro Elmarit-R 2.8 100mm (Year: 1993)
Statistics Department Seminar Series: Florian Gunsilius, Assistant Professor, Department of Economics, University of Michigan (September 23, 2022 10:00am) https://events.umich.edu/event/98097 98097-21795583@events.umich.edu Event Begins: Friday, September 23, 2022 10:00am
Location: West Hall
Organized By: Department of Statistics

Abstract: We develop a notion of projections between sets of probability measures using the geometric properties of the 2-Wasserstein space. It is designed for general multivariate probability measures, is computationally efficient to implement, and provides a unique solution in regular settings. The idea is to work on regular tangent cones of the Wasserstein space using generalized geodesics. Its structure and computational properties make the method applicable in a variety of settings, from causal inference to the analysis of object data. An application to estimating causal effects yields a generalization of the notion of synthetic controls to multivariate data with individual-level heterogeneity, as well as a way to estimate optimal weights jointly over all time periods.

Florian Gunsilius is an Assistant Professor of Economics (Econometrics) at the University of Michigan. His research interests are nonparametric approaches for statistical identification, estimation, and inference. His current focus is on developing geometric methods for causal inference and statistical optimal transport theory.

https://www.floriangunsilius.com/

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Workshop / Seminar Wed, 14 Sep 2022 14:06:17 -0400 2022-09-23T10:00:00-04:00 2022-09-23T11:00:00-04:00 West Hall Department of Statistics Workshop / Seminar Florian Gunsilius
"How to Turn Your Time Into Your Legacy." (September 23, 2022 12:30pm) https://events.umich.edu/event/99084 99084-21797549@events.umich.edu Event Begins: Friday, September 23, 2022 12:30pm
Location: GG Brown Laboratory
Organized By: Civil and Environmental Engineering

The 2022 CEE Alumni Merit recipient Mr. Larry Brinker, Jr. is the chief executive officer of Brinker, a family of five companies and a leader in commercial construction in southeast Michigan. The company is a significant contributor to the transformation of Detroit, with more than $4 billion dollars of construction projects in the past 30 years. Mr. Brinker has been widely recognized for his leadership and contributions. He was named the 2018 Entrepreneur of The Year in the Michigan and Northwest Ohio Region, and was a national finalist. He was also named a 2015 recipient of the Crain’s Detroit Business 40 Under 40 and Detroit Business Magazine 30 In Their 30’s awards.

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Lecture / Discussion Tue, 20 Sep 2022 14:00:43 -0400 2022-09-23T12:30:00-04:00 2022-09-23T14:00:00-04:00 GG Brown Laboratory Civil and Environmental Engineering Lecture / Discussion Mr. Larry Brinker, Jr.
My Journey in electrifying the world’s most popular truck (September 23, 2022 3:00pm) https://events.umich.edu/event/98392 98392-21796600@events.umich.edu Event Begins: Friday, September 23, 2022 3:00pm
Location: Chrysler Center
Organized By: Electrical and Computer Engineering

Linda Zhang is the 2022 ECE Alumni Merit Award Recipient.

Linda Zhang, chief program engineer for the F-150 Lightning, Ford’s first electric truck, will talk about her experience leading the team behind this game-changing vehicle, including the challenges and successes of shifting America’s perception of what an EV can be.

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Lecture / Discussion Fri, 09 Sep 2022 12:02:30 -0400 2022-09-23T15:00:00-04:00 2022-09-23T16:00:00-04:00 Chrysler Center Electrical and Computer Engineering Lecture / Discussion Chrysler Center
Evaluation of Phosphate Treatment and Long-Term RUNX2 Suppression On Adult Human MSC Chondrogenesis and Neo-Cartilage Formation (September 26, 2022 3:15pm) https://events.umich.edu/event/99026 99026-21797474@events.umich.edu Event Begins: Monday, September 26, 2022 3:15pm
Location: Lurie Biomedical Engineering (formerly ATL)
Organized By: Biomedical Engineering

Abstract:
Clinical repair strategies for articular cartilage defects are limited by the inability of the tissue to self-repair, often resulting in post-traumatic osteoarthritis (PTOA). PTOA arises from the degradation of structural cartilage extracellular matrix (ECM) proteins responsible for maintaining articular cartilage mechanics, such as aggrecan and collagen. Current cartilage tissue engineering strategies aim to utilize human-derived cells to regenerate cartilage prior to the onset of PTOA. Limited availability of chondrocytes – the primary cell type in articular cartilage – imposes a need for alternatives. Human mesenchymal stem cells (hMSCs) are a promising solution as they can be found in a variety of tissues and can differentiate into MSC-derived chondrocytes (MdChs). However, MSCs are limited by their inability to produce a stable chondrogenic phenotype and deposit and maintain ECM in long-term culture due to maturation, (hypertrophy) where metalloproteinases cleave collagen II and aggrecan. As a result, MSC-derived cartilage regeneration techniques are not yet suitable for clinical use. The central objective of this thesis is to increase cartilage matrix accumulation for more clinically functional cartilage tissue by increasing matrix deposition and stabilizing the chondrogenic phenotype of MSCs.

We investigated two approaches to increase cartilage ECM accumulation and improve MdCh-based cartilage tissue engineering functional outcomes: inorganic phosphate (Pi) treatment and RUNX2 suppression. First, we found that Pi increased cartilage ECM production, but also increased MdCh hypertrophy, while RUNX2 suppression increased stiffness of neo-cartilage tissues long-term. Finally, we showed that combined treatment of Pi and RUNX2 suppression exhibited reduced MdCh hypertrophy but did not significantly increase matrix accumulation. Overall, this dissertation explores methodologies that promote both cartilage matrix accumulation and reduces cartilage matrix loss during long-term culture to better support the use of MdChs in cartilage defect repair strategies.

Zoom Link: https://umich.zoom.us/j/98189564171 Password: cartilage

Committee Chair: Dr. Rhima Coleman

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Lecture / Discussion Mon, 19 Sep 2022 15:31:39 -0400 2022-09-26T15:15:00-04:00 2022-09-26T16:15:00-04:00 Lurie Biomedical Engineering (formerly ATL) Biomedical Engineering Lecture / Discussion BME PhD Defense
Taking from Charity? Political Contributions and the Market for Charitable Funds. (September 26, 2022 4:00pm) https://events.umich.edu/event/97248 97248-21794227@events.umich.edu Event Begins: Monday, September 26, 2022 4:00pm
Location: Ross School of Business
Organized By: Department of Economics

This paper estimates the effects of large donors’ political contributions on charitable contributions and fundraising. Political contributions reduce the effectiveness of charitable fundraising, particularly in the Health and Other sectors. Charities therefore reduce fundraising, which contributes to an overall elasticity of private charitable contributions to political contributions of -0.07. This aggregate effect combines large political donors’ charitable contribution behavior with spillover effects of their political giving on the charitable giving patterns of the remainder of the population. Subsequent analysis allows for heterogeneity in the ideologies of both political and charitable recipients.

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Workshop / Seminar Tue, 23 Aug 2022 10:58:16 -0400 2022-09-26T16:00:00-04:00 2022-09-26T17:30:00-04:00 Ross School of Business Department of Economics Workshop / Seminar Taking from Charity? Political Contributions and the Market for Charitable Funds.
IOE 813 Seminar Series (September 26, 2022 4:30pm) https://events.umich.edu/event/98313 98313-21796478@events.umich.edu Event Begins: Monday, September 26, 2022 4:30pm
Location: Industrial and Operations Engineering Building
Organized By: U-M Industrial & Operations Engineering

Speaker: Kevin Smith, PhD Candidate, U-M IOE

Description: Social Inequality can be defined by unequal outcomes that occur as a result of uneven distribution of resources. Many of the disparities that are observed across income quantiles occur in concentrated United States communities. Within these concentrated areas, unique social and behavioral responses exist to healthcare, health policy, and public health policy. While the US collects an enormous amount of demographic, health, and economic data at various community levels, there still exists a gap in how decision-makers can leverage these data to design appropriate community policy initiatives whose outcomes are intended to reduce the observed disparities nationwide. In this seminar, we will discuss applications of machine learning models in public health and healthcare policy and challenges in their respective outcome predictions.

Bio: Kevin B. Smith is a PhD candidate in the department of Industrial and Operations Engineering (IOE) at the University of Michigan and is co-advised by Dr. Brian Denton and Dr. Siqian Shen of IOE. His research is focused on applying industrial engineering and operations research tools to improve outcomes resulting from problems of social inequality. The mission of his research is to inform policymakers and the public of the critical factors that impact decisions with particular applications in organ allocation, pandemic risk planning, and clinical kidney stone care thus far. Additionally, he is motivated to allocate resources equitably and improve decision-making outcomes in these settings. His work aims to highlight systemic shortcomings of current healthcare and public health policies and create models that derive equitable outcomes using interpretable and accessible results.

The seminar series “Providing Better Healthcare through Systems Engineering” is presented by the U‐M Center for Healthcare Engineering and Patient Safety (CHEPS): Our mission is to improve the safety and quality of healthcare delivery through a multi‐disciplinary, systems‐engineering approach.

For the Zoom link and password, and to be added to the weekly e‐mail for the series, please RSVP or contact genehkim@umich.edu

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Workshop / Seminar Thu, 08 Sep 2022 11:27:41 -0400 2022-09-26T16:30:00-04:00 2022-09-26T17:30:00-04:00 Industrial and Operations Engineering Building U-M Industrial & Operations Engineering Workshop / Seminar Industrial and Operations Engineering Building