Three Keynote Speakers: 1) Franz-Ulrich Hartl, Ph.D., Managing Director of the Max Planck Institute of Biochemistry, Germany, “Mechanisms of Aggregate Toxicity and Their Modulation by Molecular Chaperones,” 2) Judith Frydman, Ph.D., Professor, Biology and Genetics, Stanford University, "Chaperone Mediated Proteostasis in Health and Disease," 3) Tom A. Rapoport, Ph.D., Professor of Cell Biology, Howard Hughes Medical Institute Investigator, Harvard Medical School, "How the ER Gets Into Shape"