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Presented By: Quantitative Biology Seminars

Special Quantitative Biology Seminar | From Interfacial Tubulation in Alcanivorax Borkumensis Biofilms to Buckling of Liquid-Crystal Membranes

Carles Blanch Mercader (Institut Curie, Paris)

Anisotropic cells can exhibit long-range orientational order and topological defects, which often influence their dynamics during shape formation. In the first part of this talk, I will present conditions for a morphological transition between a spherical and a dendritic phase in Alcanivorax borkumensis biofilm-covered oil microdroplets. Using phase-field approaches, we studied how tubulation dynamics on 2d liquid-liquid interfaces are modified by bacteria proliferation with an homeostatic state. Experimental observations demonstrate preferential interfacial tubulation at topological defects, with bacterial assemblies on the tubes exhibiting long-range nematic order. The second part of this talk focuses on the impact of explicit order-curvature couplings on the buckling of liquid-crystal membranes at integer topological defects. We identified conditions that lead to the instability of flat membranes, highlighting the profound influence of order-curvature coupling. These results show how bacteria biofilms can utilize topological defects to facilitate membrane deformation and enhance oil access.

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