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Presented By: LSA Biophysics

Super-resolution imaging of intracellular transport along the microtubule cytoskeleton

Melike Lakadamyali (University of Pennsylvania)

Microtubules play important roles as highways for intracellular transport. I will highlight how super-resolution microscopy and single molecule tracking tools have enabled us to map the mobility of organelles moving along individual microtubules and study how microtubule post translational modifications impact cellular processes like autophagy. Finally, I will talk about recent work determining the mechanisms by which specific post translational modifications become enriched on microtubule subsets.

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