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Presented By: Ecology and Evolutionary Biology

EEB Thursday Seminar Series - Using gene genealogies to understand complex traits

Doc Edge, University of Southern California

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This event is part of our weekly Thursday Seminar Series.

About: Ancestral recombination graphs (ARGs) use trees to relate variation in a sample of genomes to the genealogical sources of that variation. Recent computational advances have enabled the largest-scale ARG estimates to date, raising the possibility of ARG-based approaches to any data analysis that takes genetic variation as input. In this talk, I will discuss ways in which estimated ARGs can interface with the study of complex traits. These projects highlight the ARG---and the marginal trees it encodes---as a common language for relating evolutionary and statistical genetics.


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