Presented By: Ecology and Evolutionary Biology
EEB Thursday Seminar Series - Immune System Optimization in a Variable World
Ann T. Tate, Vanderbilt University, Assistant Professor of Biological Sciences
This event is part of our ongoing Thursday seminar series!
About: A maximal immune response is not always an optimal one. Immune responses are energetically costly and prone to causing collateral damage to the host. Moreover, arms of the immune response effective against a parasite may render hosts more susceptible to others, and constraints at the genetic level could limit a response or force trade-offs with other life-history traits. In this talk, Tate will present experimental and theoretical work that takes advantage of natural immunological variation among flour beetle populations and other insect species to examine the roles of coinfection, metamorphosis, and genetic pleiotropy in shaping the evolution of innate immune systems and host susceptibility to infection.
website: https://my.vanderbilt.edu/tatelab/
About: A maximal immune response is not always an optimal one. Immune responses are energetically costly and prone to causing collateral damage to the host. Moreover, arms of the immune response effective against a parasite may render hosts more susceptible to others, and constraints at the genetic level could limit a response or force trade-offs with other life-history traits. In this talk, Tate will present experimental and theoretical work that takes advantage of natural immunological variation among flour beetle populations and other insect species to examine the roles of coinfection, metamorphosis, and genetic pleiotropy in shaping the evolution of innate immune systems and host susceptibility to infection.
website: https://my.vanderbilt.edu/tatelab/
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