Huttenlocher will discuss her lab's research at the interface of cell biology and immunology. Their work is centered on understanding innate immune inflammation and its resolution. They seek to dissect how external cues and cell signaling networks regulate neutrophil migration during tissue damage and repair and how this is altered in human disease.

Speaker:

Anna Huttenlocher, M.D., is the Anna Ruth Brummett Professor of Pediatrics and Medical Microbiology and Immunology at the University of Wisconsin Medical School. Her laboratory is focused on understanding the basic molecular mechanisms that regulate cell migration in response to tissue damage and repair. They are particularly interested in the basic mechanisms that mediate neutrophil inflammation and its resolution. They have extensive experience with cell migration research, host pathogen interactions and live cell imaging using both organotypic models and zebrafish as a model system. The group has developed disease models of wound healing, cancer and chronic inflammation using zebrafish, and has has a strong track record in resource generation and in sharing reagents with the research community.

Huttenlocher is a member of the National Academy of Medicine, was chair of the Gordon conference on Directed cell migration, co-chaired a Banbury conference, served on council for the American Society of Cell Biology, serve as a senior editor at the Journal of Cell Biology and was Chair of a NIH study section. She has been committed to the education of Ph.D. and M.D. scientists in both basic and translational research. Many of her former trainees run independent research programs, including at RIKEN Japan, University of Colorado-Boulder, University of Connecticut, Purdue University, University of Wisconsin, University of Iowa, Rutgers University and Albert Einstein.