My research interest is centered on a very reliable organic reaction - the copper-catalyzed cycloaddition of sulfonyl azides and terminal alkynes (CuAAC). Differential fragmentation of the resulting 1,2,3-triazole generates ketenimines or rhodium carbenoids which readily engage with a variety of nucleophiles to provide access to heterocycles of interest to the synthetic community. We’ve demonstrated the utility of click chemistry in the synthesis of N-Heterocycles such as indolizines, dihydroisoquinolines and as an approach to beta-lactams.