Presented By: DCMB Seminar Series
CCMB/DCMB Weekly Seminar Series featuring Ting Wang, PhD (Professor of Medicine and Head, Department of Genetics WashU Medicine)
CCMB/DCMB Seminar by Ting Wang, PhD
"Unmasked: transposable elements as drivers and targets in cancer"
Abstract
Transposable elements (TEs) represent almost half of the human genome. Historically deemed ‘junk DNA’, recent technological advancements have stimulated a wave of research into the functional impact of TEs on gene-regulatory networks in evolution and development, as well as in diseases including cancer. The genetic and epigenetic evolution of cancer involves the exploitation of TEs, whereby TEs contribute directly to cancer-specific gene activities. I will provide a perspective on the role of TEs in cancer as being a ‘double-edged sword’, both promoting cancer evolution and representing a vulnerability that could be exploited in cancer therapy.
The CCMB Seminar Series (Sponsored by DCMB) is held at Medical Science Building 1 (MS1), Room 4B700, each Wednesday, at 4:00 pm EST, on bioinformatics-related topics.Each seminar is presented by an invited guest speaker. These seminars are live-streamed on Zoom.
"Unmasked: transposable elements as drivers and targets in cancer"
Abstract
Transposable elements (TEs) represent almost half of the human genome. Historically deemed ‘junk DNA’, recent technological advancements have stimulated a wave of research into the functional impact of TEs on gene-regulatory networks in evolution and development, as well as in diseases including cancer. The genetic and epigenetic evolution of cancer involves the exploitation of TEs, whereby TEs contribute directly to cancer-specific gene activities. I will provide a perspective on the role of TEs in cancer as being a ‘double-edged sword’, both promoting cancer evolution and representing a vulnerability that could be exploited in cancer therapy.
The CCMB Seminar Series (Sponsored by DCMB) is held at Medical Science Building 1 (MS1), Room 4B700, each Wednesday, at 4:00 pm EST, on bioinformatics-related topics.Each seminar is presented by an invited guest speaker. These seminars are live-streamed on Zoom.
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