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Presented By: Department of Molecular, Cellular, and Developmental Biology

Taste Perception and Internal Nutrient Sensing in Drosophila

Hubert Amrein, Texas A&M Health Science College of Medicine

graphic showing micro image and chart of intercellular glucose levels over time graphic showing micro image and chart of intercellular glucose levels over time
graphic showing micro image and chart of intercellular glucose levels over time
The fly brain harbors a small subset of neurons capable of gluconeogenesis. These neurons express the critically important enzyme Glucose­6­Phosphatase (green), and a subset of them also express NPY, a neuropeptide implicated in feeding regulation, fat metabolism, and numerous other processes. Neural gluconeogenesis regulates glucose and glycogen levels in flies that experience starvation, revealing an novel mechanism of metabolic regulation of energy carriers.

Host: Monica Dus
graphic showing micro image and chart of intercellular glucose levels over time graphic showing micro image and chart of intercellular glucose levels over time
graphic showing micro image and chart of intercellular glucose levels over time

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