This seminar will focus on our recent progress in developing new catalysts and strategies for chemical synthesis. Our group has a long-term interest in developing catalyst-controlled nucleophile addition processes that enable new approaches to stereoselective C–C bond construction. In this regard, the development of catalytic enantioselective reactions of boron-stabilized alkylmetals will be discussed. In addition, the design and development of electrophilic carbon(0) ligated rhodium(I) complexes for catalytic site- and enantioselective hydrofunctionalizations of olefins will be presented.
Simon Meek (University of North Carolina)