The discovery of graphene has stimulated not only the field of carbon nanoelectronics, but also studies of novel electronic phenomena in a wide range of 2D van der Waals’ materials. In this talk, I will discuss our recent studies on two seemingly unrelated 2D materials: non-centrosymmetric superconducting NbSe_2 and magnetic CrI_3. As a result of the crystal symmetry and spin-orbit interactions, the electron spins in both of these materials become Ising-like (i.e. spins locked to the out-of-plane direction), giving rise to unique magnetic properties. First I will discuss how the Ising spins in 2D NbSe_2 protect superconductivity under very high magnetic fields and experimental signatures of spin-triplet pairing correlations through tunneling measurements. I will then discuss our recent efforts in studying 2D magnetism in CrI_3 by electric fields. If time allows, I will briefly discuss interesting future directions by combining these two materials to form heterostructures.