Skip to Content

Sponsors

No results

Tags

No results

Types

No results

Search Results

Events

No results
Search events using: keywords, sponsors, locations or event type
When / Where
All occurrences of this event have passed.
This listing is displayed for historical purposes.

Presented By: Department of Chemistry

Single protein dynamics at soft interfaces: Can physical chemistry solve a $100,000,000,000 problem?

Christy Landes (Rice University)

Understanding nanoscale protein dynamics at interfaces is crucial for topics ranging from disease inception and drug delivery to separations science. Recent efforts by our group and others have shown the promise of applying single molecule methods to link mechanistic detail about protein adsorptions to macroscale observables. When we study one molecule at a time, we eliminate ensemble averaging, thereby accessing any underlying complexity. However, we must develop new methods to increase information content in the resulting low density and low signal-to-noise data and to improve space and time resolution.

I will highlight recent advances in super-resolution microscopy for quantifying the physics and chemistry that occur between target proteins and stationary phase supports during chromatographic separations. My discussion will concentrate on the newfound ability of super-resolved single protein spectroscopy to inform theoretical parameters via quantification of adsorption-desorption dynamics, protein unfolding, and nano-confined transport.

















Christy Landes (Rice University)

Explore Similar Events

  •  Loading Similar Events...

Back to Main Content