Skip to Content

Sponsors

No results

Tags

No results

Types

No results

Search Results

Events

No results
Search events using: keywords, sponsors, locations or event type
When / Where
All occurrences of this event have passed.
This listing is displayed for historical purposes.

Department of Chemistry pres.

Chemical Regulation of Functional RNAs

Yunsun Nam (UT Southwestern Medical Center)

We study the mechanisms of specificity and regulation of enzymes that act on RNA. We identified the molecular basis for how a small molecule, heme, affects microRNA processing enzyme Drosha. We show that heme acts as a signaling factor to switch on processing of a subset of microRNAs. Other chemicals such as S-adenosylmethioinine, and transfer of its methyl group to RNA, can also have a big role in RNA-mediated gene regulation. We show the mechanistic details of how RNA methylation is accomplished, using crystal structures and biochemical studies.








Yunsun Nam (UT Southwestern Medical Center)
Report Event As Inappropriate Contact Event Organizers
Back to Main Content