Over the last few years a significant effort has been directed towards unconventional imaging techniques, such as microscopy without lenses as it can overcome some of the drawbacks associated with tradition optical microscopy, that rely on objective lenses, which results in a trade-off between the field of view and the resolution. Thus lens-less microscopy allows imaging and analysis over a wide area, enabling high throughput measurements, in addition to being cost-effective and portable. In this type of microscopy, the images are computationally reconstructed from in-line holograms, which result from the interference between the scattered optical wave from the sample and the directly transmitted wave. Here, I will present about lens-free on-chip microscopy designs, image reconstruction and its utility towards a wide range of applications related to sizing of nanoparticles, nanoparticle-aggregation, bio-sensing of pathogens and rare cancer cells, characterization of polymer degradation, material properties and rheology.











Aniruddha Ray