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Presented By: Biomedical Engineering

Zhen Xu, PhD: Histotripsy Webinar

Histotripsy for Treatment of Cancer and Neurological Diseases

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NOTICE: This will be held online. Click the link below to register.

https://fusfoundation.zoom.us/webinar/register/WN_Hj_R2DMOT8SlOAp0WRLV3A

Oftentimes when we think of focused ultrasound, we imagine using it to heat and kill tissue. Unlike thermal ablation, histotripsy uses focused ultrasound to mechanically disrupt the target tissue without heating. Histotripsy turns the tissue into liquid-appearing acellular debris – which is absorbed by the body over one to two months – resulting in effective tissue removal.

Histotripsy has been shown to stimulate a powerful immune response in cancer treatment studies. In the treatment of neurological diseases, transcranial histotripsy can produce well-confined focal treatment in a wide range of locations and volumes in the brain, offering the potential to increase the treatment envelope while decreasing treatment time.

Please register to join us at 10:00 AM Eastern on Wednesday, March 25, when Zhen Xu, PhD, will discuss the basic mechanism, instrumentation, bioeffects, and applications of histotripsy. She will also cover the latest preclinical and clinical trial results of developing histotripsy for the treatment of cancer and neurological diseases.

About the Speaker

Zhen Xu, PhD, is a tenured Associate Professor in the Department of Biomedical Engineering at the University of Michigan and a primary inventor and pioneer in histotripsy.

She has received many notable awards, including:
IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society Outstanding Paper Award (2006)
American Heart Association Outstanding Research in Pediatric Cardiology (2010)
National Institutes of Health (NIH) New Investigator Award at the First National Institute of Biomedical Imaging and Bioengineering (NIBIB) Edward C. Nagy New Investigator Symposium (2011)
The Federic Lizzi Early Career Award from The International Society of Therapeutic Ultrasound (ISTU) (2015)
Fellow of the American Institute of Medical and Biological Engineering (2019)
Dr. Xu is currently an associate editor for three notable journals: IEEE Transactions on Ultrasound, Ferroelectrics, and Frequency Control (UFFC); Frontiers in Bioengineering; and BME Frontiers. She is an elected board member of ISTU, a charter member of the US NIH study section, and a principal investigator of grants funded by the Focused Ultrasound Foundation, NIH, American Cancer Association, Office of Naval Research, The Hartwell Foundation, and The Coulter Foundation.

She received her PhD from the University of Michigan in 2005.
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