The effects of physical activity and sleep on mental and physical well-being have long been studied. More recently, there has also been an effort to understand how one’s environment impacts daily health behaviors and related outcomes. However, much of this work has been limited to subjective measures and correlational data. The current study leverages data from a prospective cohort study of medical residents as they transition from medical school to internship to address these identified gaps. This talk will discuss findings regarding the effect of changes in specific neighborhood characteristics on physical activity and sleep outcomes, as well as future projects designed to expand upon this work and explore clinical outcomes.