Abstract:

The microbiome represents an exciting frontier in medicine, and early successes in the field have demonstrated the dynamic interactions among individual microbial species and highlighted the crosstalk between microbiota and their hosts at the mucosal interface.  The Li research group in the Department of Bioengineering at Northeastern University focuses on the development of molecular and live cell-based therapeutics, with a major emphasis on harnessing innovative synthetic biology and drug delivery approaches for improving human health in a sustainable manner. In this talk, I will present our work from the past three years in interrogating and manipulating commensal bacteria and probiotics as therapeutic platforms to promote human health.

Bio:

Jiahe Li obtained his PhD in Biomedical Engineering at Cornell University in 2015, where he leveraged synthetic biology approaches and cell biology to engineer bacteria and platelets as platforms for treating metastatic cancer. Later, he pursued his postdoctoral training at the Koch Institute for Integrative Cancer Research at MIT from 2015-2018, where he gained complementary expertise in polymer science and gene delivery. He started a tenure-track faculty position in the Department of Bioengineering at Northeastern University in 2019, and his current research is supported by NIH, DoD, and various biotech companies.

Zoom Link: https://umich.zoom.us/j/97247012805