The ChE Seminar Series features guest speakers from various research backgrounds throughout the year. ChE faculty and graduate students are especially encouraged to attend.

Abstract:
T cell-based therapies are revolutionizing the treatment of some types of cancer, but currently suffer from a number of limitations. To address these challenges, we are developing biomaterials capable of concentrating, interrogating, and manipulating stem and immune cells ex vivo and in the body by controlling, in space and time, the interaction of the cells with various immunomodulatory cues. Therapeutic cancer vaccines and the development of artificial antigen presenting cells for the manufacturing and in vivo boosting of adaptive T cell-based therapies will be highlighted.

Speaker Bio:
David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and immunotherapy. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors. His inventions have been licensed by over 20 companies, leading to commercialized products. He has founded companies and is active on industrial scientific advisory boards.