We study optimal estimation when the likelihood may be misspecified. Building on tools from the theory of decision-making under uncertainty, we analyze a class of axiomatically grounded optimality criteria which nests several existing misspecification-robust objectives. Within this class, we introduce the constrained multiplier criterion, which allows for flexible misspecification attitudes. We prove a local asymptotic minimax theorem for this criterion, extending a classical efficiency bound to a limit experiment which incorporates both misspecification concerns and moment constraints. We characterize asymptotically optimal estimators as Bayes decision rules under a flat prior and an exponentially tilted likelihood that incorporates the moment constraints, and show that feasible plug-in analogs are asymptotically optimal.