Why do we sleep? What happens in our brain during sleep? How does synaptic activity affect our sleep and vice-versa? Scientists have been keen to answer these questions.

In this talk, I will survey through three synaptic hypotheses of sleep: 1. Synaptic Homeostasis Hypothesis(SHY) 2. Network Homeostasis Hypothesis 3. Phosphorylation Hypothesis. And I will present current computational works of a calcium plasticity model that can potentially test one or more of those three hypotheses.
Speaker(s): Guanhua Sun (University of Michigan)